| 哺乳动物前脑中谷氨酸能突触的分子结构 |
Peukes, J. |
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N/A |
The molecular infrastructure of glutamatergic synapses in the mammalian forebrain |
| 基于物种独立性假设的随机群落模型中的Jaccard相异度 |
Iritani, R. |
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N/A |
Jaccard dissimilarity in stochastic community models based on the species-independence assumption |
| 婴儿的大脑中视觉类别表征何时出现？ |
Yan, X. |
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N/A |
When Do Visual Category Representations Emerge in Infants' Brains? |
| 用于分析光纤光度实验中试验级时间动态的统计框架 |
Loewinger, G. |
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N/A |
A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments |
| 物种共存边缘距离的分布 |
DESALLAIS, M. |
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N/A |
The distribution of distances to the edge of species coexistence |
| 资源可用性与亲本觅食策略对幼年麻雀个体特化作用的影响 |
Ricote, N. |
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N/A |
The Interplay of Resource Availability and Parent Foraging Strategies on Juvenile Sparrow Individual Specialization |
| Pannexin 1 和 Pannexin 3 在皮肤鳞状细胞癌的肿瘤发生特性中发挥不同的调控作用。 |
O'Donnell, B. L. |
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N/A |
Pannexin 1 and Pannexin 3 differentially regulate the tumorigenic properties of cutaneous squamous cell carcinoma |
| 训练有素的跑步者中长距离跑步表现指标受先进跑鞋技术钉的影响 |
Rodrigo-Carranza, V. |
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N/A |
Influence of advanced footwear technology spikes on middle- and long-distance running performance measures in trained runners |
| 通过蛋白质结构扩散实现精确构象采样 |
Fan, J. |
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N/A |
Accurate Conformation Sampling via Protein Structural Diffusion |
| 莱姆病螺旋体伯氏疏螺旋体外表面蛋白C（OspC）的精细人源B细胞表位图谱 |
Freeman-Gallant, G. |
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N/A |
A refined human linear B cell epitope map of Outer surface protein C (OspC) from the Lyme disease spirochete, Borreliella burgdorferi |
| 脂质-siRNA偶联物进入血管周运输机制，并在中枢神经系统中实现广泛而持久的敲低效果。 |
Sorets, A. |
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N/A |
Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system |
| 量化为向量场的神经网络 |
Szeier, S. |
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N/A |
Neuronal networks quantified as vector fields |
| 鸟类白蛋白糖基化速率的变异表明其对相对高血糖的抵抗力，而非符合生命节奏综合征假说。 |
Moreno Borrallo, A. |
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N/A |
Variation in albumin glycation rates in birds suggests resistance to relative hyperglycaemia rather than conformity to the pace of life syndrome hypothesis |
| 有袋类动物的免疫保护机制受到抗菌肽cathelicidin增强子共享和基因簇重复的影响。 |
Park, J. |
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N/A |
Marsupial immune protection is shaped by enhancer sharing and gene cluster duplication of cathelicidin antimicrobial peptides |
| 组蛋白去甲基酶LSD1在隐球菌感染期间调节脂质稳态 |
Lohia, G. K. |
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N/A |
Histone demethylase LSD1 regulates lipid homeostasis duringCryptococcus neoformans infection |
| 食品污染物脱氧雪腐镰刀菌烯醇的低浓度可引发凋亡并损害促性腺激素释放激素诱导的垂体类促性腺细胞中黄体生成素分泌。 |
Cai, G. |
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N/A |
Low concentrations of the food contaminant Deoxynivalenol trigger apoptosis and impair GnRH-induced LH secretion in pituitary gonadotrope-like cells |
| 葡萄藤细胞对生理剂量乙醇的反应，其中包括诱导对热应激的抗性。 |
Diot, A. |
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N/A |
Responses of grapevine cells to physiological doses of ethanol, among which induced resistance to heat stress |
| 在不对称细胞分裂过程中，线粒体的非随机分离有助于子细胞命运的分化。 |
Segos, I. |
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N/A |
Non-random segregation of mitochondria during asymmetric cell division contributes to cell fate divergence in daughter cells |
| 巨噬细胞内在的MDA5-IRF5轴驱动HIV-1 icRNA诱导的炎症反应 |
Ramaswamy, S. |
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N/A |
Macrophage-intrinsic MDA5-IRF5 axis drives HIV-1 icRNA-induced inflammatory responses |
| 赖氨酸82的乙酰化通过破坏其核输入，启动TDP-43的核功能丧失。 |
Zhang, S. |
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Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import |
| 几何推导的动作电位标记用于模型开发：一种有原则的方法？ |
Clerx, M. |
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N/A |
Geometrically-derived action potential markers for model development: a principled approach? |
| 依赖于压电效应（PIEZO）的微环境机械感应对于肠道干细胞命运决定和维持至关重要。 |
Baghdadi, M. B. |
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N/A |
PIEZO-dependent mechano-sensing of the niche is essential for intestinal stem cell fate decision and maintenance |
| 在表皮发育过程中，隔膜连接成分在信号通路调控和细胞极性方面具有独特的非封闭功能 |
Holtwick, V. |
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N/A |
Distinct Non-occluding Functions of Septate Junction Components in Signaling Pathway Regulation and Cell Polarity During Epithelial Development |
| α-连环蛋白的磷酸化在有丝分裂期间升高，以抵抗顶端圆化和上皮屏障泄漏。 |
Le, P. M. |
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N/A |
α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak |
| PI3K/AKT信号通路通过c-myc介导应激诱导的淀粉样蛋白聚集 |
Lacroix, E. |
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N/A |
PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc |
| 白色念珠菌中的五EF-手蛋白Pef1在膜扰动位点发挥作用，以支持极性生长和膜完整性。 |
Weichert, M. |
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N/A |
The penta-EF-hand protein Pef1 of Candida albicans functions at sites of membrane perturbation to support polarized growth and membrane integrity |
| 节点调制器（NOMO）是一种承载力的跨膜蛋白，对于肌肉分化是必需的。 |
Naughton, B. |
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N/A |
Nodal Modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation |
| GDF11分泌细胞移植能有效改善与年龄相关的肺纤维化 |
Nagy, A. |
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N/A |
GDF11 secreting cell transplant efficiently ameliorates age-related pulmonary fibrosis |
| Pax转录因子EGL-38将EGFR信号传导与秀丽隐杆线虫阴门中特定细胞类型的顶端细胞外基质的组装联系起来。 |
Schmidt, H. F. |
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N/A |
The Pax transcription factor EGL-38 links EGFR signaling to assembly of a cell-type specific apical extracellular matrix in the Caenorhabditis elegans vulva |
| 发育中的人类视网膜的睫状缘区在妊娠晚期之前一直维持着视网膜祖细胞。 |
Eldred, K. C. |
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N/A |
Ciliary marginal zone of the developing human retina maintains retinal progenitor cells until late gestational stages |
| Wnt/β-连环蛋白信号传导支撑了肝片吸虫幼虫的生长和发育。 |
Armstrong, R. |
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N/A |
Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development |
| RNA结合调控级联控制果蝇雄性生殖系干细胞谱系中从增殖到分化的转变 |
Harris, D. E. |
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N/A |
An RNA binding regulatory cascade controls the switch from proliferation to differentiation in the Drosophila male germ line stem cell lineage |
| 盐诱导激酶对牙槽骨发育、稳态及牙槽窝愈合的调控作用 |
Tokavanich, N. |
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N/A |
Control of alveolar bone development, homeostasis, and socket healing by salt inducible kinases |
| 一种简单的围产期哺乳动物卵巢免疫组织化学方法揭示了由DNA损伤和非联会引起的卵母细胞凋亡的不同动力学。 |
Kogo, H. |
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N/A |
A simple immunohistochemical method for perinatal mammalian ovaries revealed different kinetics of oocyte apoptosis caused by DNA damage and asynapsis. |
| 胰岛初级纤毛中轴丝动力蛋白的扩展显微镜观察 |
Dong, X. |
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N/A |
Expansion microscopy of axonemal dyneins in islet primary cilia |
| 单细胞转录组分析揭示CD34作为人类窦房结起搏细胞的新型标志物 |
Lim, A. A. |
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Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes |
| 钙蛋白酶在膜修复过程中调控含有膜联蛋白的微囊泡的分泌 |
Williams, J. K. |
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N/A |
Calpains Orchestrate Secretion of Annexin-containing Microvesicles during Membrane Repair |
| 果蝇肌生成抑制因子Him基因对于成年肌肉功能和肌肉干细胞的维持至关重要。 |
Mitchell-Gee, R. |
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N/A |
The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance |
| 刺胞动物胚胎中的平面细胞极性协调为动物体轴的进化提供了线索。 |
Uveira, J. |
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N/A |
Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution |
| 中等剂量砷暴露会损害小鼠肾单位的形成 |
Alonso, C. A. I. |
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N/A |
Mouse nephron formation is impaired by moderate-dose arsenical exposure |
| 计算机靶点识别揭示IL12B为小分子药物开发的候选靶点 |
Tanner, T. J. |
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In Silico Target Identification Reveals IL12B as a Candidate for Small Molecule Drug Development |
| 腺样囊性癌中HLA I类分子的可逆性下调 |
Li, A. |
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N/A |
Reversible Downregulation of HLA Class I in Adenoid Cystic Carcinoma |
| 利用作物模型引导的机器学习方法，从数据稀疏的田间试验中估算土壤矿质氮 |
Gupta, R. |
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N/A |
Estimating soil mineral nitrogen from data-sparse field experiments using crop model-guided machine learning approach |
| 在莱茵衣藻中敲除羧基转移酶互作蛋白1（CTI1）使其油脂含量提高了五倍，同时不影响细胞生长。 |
Li, Z. |
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N/A |
Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth |
| 远程缺血预处理通过CD36介导的吞噬作用减轻跨神经元退化并促进中风恢复。 |
Ju, H. |
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N/A |
Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis. |
| 寡聚原花青素对中性粒细胞胞外陷阱的抑制作用通过肠-肾轴减轻化疗诱导的慢性肾损伤 |
Luan, Y. |
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N/A |
Inhibition on neutrophil extracellular traps by oligomeric procyanidins alleviate chemotherapy-induced chronic kidney injury via gut-kidney axis |
| 高效多重非病毒工程化及扩增多克隆γδ CAR-T细胞用于免疫治疗 |
Bridge, J. |
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N/A |
Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy |
| 副粘病毒基质蛋白通过与细胞质中的外显子连接复合体相互作用，调节宿主细胞的翻译过程。 |
Hung, C.-T. |
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N/A |
Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm |
| 澳大利亚犬钩虫（Ancylostoma caninum）中广泛存在苯并咪唑抗性单核苷酸多态性（SNPs） |
Abdullah, S. |
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N/A |
Widespread occurrence of benzimidazole resistance SNPs in the canine hookworm, Ancylostoma caninum, in Australia |
| 数据发布：使用FIB-SEM和机器学习对P7小鼠组织微观结构进行高分辨率成像和分割 |
Ackerman, D. |
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N/A |
Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning |
| 基因型和年龄对无菌SCID猪仔体内特定微生物群的影响 |
Widmer, K. M. |
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N/A |
Effect of Genotype and Age on a Defined Microbiota in Gnotobiotic SCID Piglets |
| 鬣蜥属（Chamaeleo calyptratus，又称面纱变色龙）染色体规模的基因组组装和注释为爬行动物的进化和发育机制提供了深入见解。 |
Shylo, N. |
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N/A |
Chamaeleo calyptratus (veiled chameleon) chromosome-scale genome assembly and annotation provides insights into the evolution of reptiles and developmental mechanisms. |
| 老年小鼠表现出更快的静脉注射阿片类药物自我给药获取速度，但对摄入量的影响不一。 |
Sharpe, A. L. |
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N/A |
Aged mice exhibit faster acquisition of intravenous opioid self-administration with variable effects on intake |
| 为体外膜氧化治疗期间的医疗设备进行计算机模拟临床试验生成虚拟患者数据 |
Landoll, M. |
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N/A |
Generating virtual patient data for in-silico clinical trials of medical devices during extracorporeal membrane oxygenationtreatment |
| 全原子连续恒定pH分子动力学中的力场限制 |
Peeples, C. |
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N/A |
Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics |
| 人诱导多能干细胞衍生的心肌细胞的激发计算研究 |
Shetty, R. |
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N/A |
Computational Study of the Excitation of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes |
| T1D患者和进展者的性别特异性细胞因子、趋化因子和生长因子特征 |
Girdhar, K. |
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N/A |
Sex-Specific Cytokine, Chemokine, and Growth Factor Signatures in T1D Patients and Progressors |
| 城市化的生态和进化影响：应用因果建模框架 |
Borden, J. B. |
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N/A |
Ecological and evolutionary impacts of urbanization: applying a causal modeling framework |
| CD4+Foxp3E2+调节性T细胞频率可预测乳腺癌的预后和复发。 |
Fusco, C. |
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N/A |
CD4+Foxp3E2+ regulatory T cell frequency predicts breast cancer prognosis and recurrence |
| 在乳头状病毒感染后两周，侵袭性癌症和自发性消退 |
Bilger, A. |
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N/A |
Invasive cancer and spontaneous regression two weeks after papillomavirus infection |
| 探索辣椒素对胃癌细胞基因表达及化疗增敏作用的影响 |
Meng, W. |
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N/A |
Exploring the effect of capsaicin on gene expression and chemotherapy sensitization in gastric cancer cells |
| 特定于脑桥的轴突微环境支持新发的胶质瘤生成 |
Xie, Z. |
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N/A |
A pontine-specific axonal niche supports de novo gliomagenesis |
| 铁死亡与细胞凋亡的相互作用及其通过BH3模拟物的调节 |
Qiu, Y. |
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N/A |
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics |
| Claudin-4 对细胞核-细胞周期交叉对话的重塑维持了卵巢肿瘤基因组的稳定性，并推动了对诱导基因组不稳定性药物的抗性。 |
Bitler, B. G. |
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N/A |
Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents. |
| 肾母细胞瘤中亚型特异性的进化模式及与临床相关的基因组不稳定性 |
Cresswell, G. D. |
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N/A |
Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour |
| 温度敏感的谷氨酸门控AMPA亚型iGluRs |
Kumar Mondal, A. |
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N/A |
Temperature Sensitive Glutamate Gating of AMPA-subtype iGluRs |
| 将细菌素合成多重化以杀灭和预防抗菌药物耐药性 |
Quintero-Yanes, A. |
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N/A |
Multiplexing bacteriocin synthesis to kill and prevent antimicrobial resistance |
| C7取代的喹啉作为鲍曼不动杆菌中AdeG外排泵的有效抑制剂 |
Zhu, Y. |
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N/A |
C7-substituted Quinolines as Potent Inhibitors of AdeG Efflux Pumps in Acinetobacter baumannii |
| 人转铁蛋白和乳铁蛋白协同支持脑膜炎奈瑟菌在小鼠鼻咽部的定殖 |
Lee, I. S. |
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N/A |
Human transferrin and lactoferrin cooperatively support Neisseria meningitidis colonization in the murine nasopharynx |
| 优化数字PCR检测方法以实现地表水中多重微生物来源追踪 |
Ghosh, S. |
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N/A |
Optimizing Digital PCR Assays for Multiplexed Microbial Source Tracking in Surface Waters |
| 社区范围内的相互作用维持了地热泉生境中的生命 |
Stephens, T. G. |
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N/A |
Community-wide interactions sustain life in geothermal spring habitats |
| 工程改造亚洲象TP53：TP53逆转录基因敲除激活了常见且独特的与癌症相关的通路 |
Karpinski, E. |
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N/A |
Engineering Asian elephant TP53: TP53 retrogene knockouts activate common and unique cancer-relevant pathways |
| 使用CycloneSEQ高效构建完整基因组以填补细菌草图组装中的空缺 |
Liang, H. |
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N/A |
Efficiently Constructing Complete Genomes with CycloneSEQ to Fill Gaps in Bacterial Draft Assemblies |
| 来自Thermotoga naphthophila的GH10家族热稳定木聚糖酶的3D建模：重组木聚糖酶的特性研究 |
Waris, A. |
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N/A |
3D modeling of thermostable xylanase from Thermotoga naphthophila a member of GH10 family: characterization studies of recombinant xylanase |
| Vps4底物结合及其耦合机制：Vps4p底物招募与从自抑制中释放 |
Wienkers, H. |
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N/A |
Vps4 substrate binding and coupled mechanisms of Vps4p substrate recruitment and release from autoinhibition |
| H/ACA snoRNP在加入核心90S前体核糖体之前，引导核糖体RNA亚域在卫星颗粒中进行折叠。 |
Fischer, P. |
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N/A |
H/ACA snoRNP guides ribosomal RNA subdomain folding in a satellite particle before joining the core 90S pre-ribosome |
| 人类DNA复制起始位点通过5-甲基脱氧胞苷的氧化作用在表观遗传学上被指定。 |
Krude, T. |
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N/A |
Human DNA replication initiation sites are specified epigenetically by oxidation of 5-methyl-deoxycytidine |
| 抑制特定Zn2+依赖性DUB活性及炎症的分子胶 |
Chandler, F. |
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N/A |
Molecular glues that inhibit specific Zn2+-dependent DUB activity and inflammation |
| 通过部分酶解植物细胞壁实现活体植物蛋白质的直接核递送 |
Gu, Q. |
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N/A |
Direct Nuclear Delivery of Proteins on Living Plant via Partial Enzymatic Cell Wall Digestion |
| 选择性激动肝脏和肠道FXR可预防肠外喂养新生猪的胆汁淤积和肠道萎缩 |
Jiang, Y. |
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N/A |
Selective Agonism of Liver and Gut FXR Prevents Cholestasis and Intestinal Atrophy in Parenterally Fed Neonatal Pigs |
| 不同吸湿性肥料颗粒的离散元模型构建及施肥排放验证 |
Chen, X. F. |
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N/A |
Construction of Discrete Element Model of Different Moisture Hygroscopic Fertilizer Particles and Fertilizer Discharging Verification |
| 高粱通过根系分泌物进行的邻近感知影响植物生理和生产力 |
Ben-Zeev, S. |
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N/A |
Neighbor sensing through rhizodeposits in sorghum affects plant physiology and productivity |
| 哺乳动物类胚胎发育的蛋白质组图谱及时间动态变化 |
Garge, R. K. |
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N/A |
The proteomic landscape and temporal dynamics of mammalian gastruloid development |
| AxonFinder：肿瘤侵袭神经纤维的自动分割 |
Ait-Ahmad, K. |
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N/A |
AxonFinder: Automated segmentation of tumor innervating neuronal fibers |
| 大型齿鲸种内体型变异的总结 |
McClure, J. |
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N/A |
A summary of intraspecific size variation for large odontocetes |
| 羊角中CASP14基因的组织特异性及功能位点分析 |
Lu, X. |
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N/A |
Tissue-specific and functional loci analysis of CASP14 gene in the sheep horn |
| 离开补丁的决定和与学生相关的唤醒系统 |
Marzecova, A. |
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N/A |
Patch-leaving decisions and pupil-linked arousal systems |
| 英国版爱荷华辅音感知测试 |
Guo, X. |
PDF |
N/A |
British Version of the Iowa Test of Consonant Perception |
| 星形胶质细胞对EcoHIV感染小鼠可卡因运动性敏感化的调控 |
Xie, Q. |
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N/A |
Astrocytic Regulation of Cocaine Locomotor Sensitization in EcoHIV Infected Mice |
| 酒精饮用、焦虑及BNST神经元兴奋性的CRF神经元中食欲素受体信号传导的性别特异性作用 |
Ma, Y. |
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N/A |
Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability |
| 历史驱动的干扰抑制和目标增强的空间参考框架 |
Ilksoy, Y. |
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N/A |
The spatial reference frame of history-driven distractor suppression and target enhancement |
| 肌球蛋白XVA异构体参与了听觉毛细胞中依赖于机械转导的肌动蛋白细胞骨架重塑过程。 |
Lopez-Porras, A. I. |
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N/A |
Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia |
| 通过模拟肿瘤微环境的共培养实验鉴定增强NK细胞肿瘤杀伤活性的小分子 |
Binici, A. |
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Identification of small molecule enhancers of NK cell tumoricidal activity via a tumor microenvironment-mimicking co-culture assay |
| 针对结核分枝杆菌持久菌的DNA疫苗可缩短治愈结核病所需的治疗时间。 |
Karanika, S. |
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N/A |
Therapeutic DNA Vaccine Targeting Mycobacterium tuberculosis Persisters Shortens Curative Tuberculosis Treatment |
| 线粒体超活性和活性氧驱动对黄热病病毒-17D减毒活疫苗的先天免疫 |
Muccilli, S. G. |
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Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine |
| 来自海洋缺氧区的蓝细菌同时编码I型和II型核酮糖-1,5-二磷酸羧化酶/加氧酶（Rubisco）。 |
Jaffe, A. L. |
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N/A |
Cyanobacteria from marine oxygen deficient zones encode both form I and form II rubiscos |
| 多菌株噬菌体诱导的细菌感染清除 |
Marchi, J. |
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N/A |
Multi-strain phage induced clearance of bacterial infections |
| T型电压门控钙通道CaV3.1作为多杀性巴氏杆菌毒素的候选受体，并参与了该毒素引起的呼吸上皮屏障破坏。 |
Bi, H. |
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The T-type voltage-gated Ca2+ channel CaV3.1 as a candidate receptor for Pasteurella multocida toxin and contributes to the disruption of respiratory epithelial barrier induced by the toxin |
| 合理选择TbpB变体阐明了针对淋病奈瑟菌的广谱覆盖双价疫苗配方 |
Fegan, J. E. |
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Rational selection of TbpB variants elucidates a bivalent vaccine formulation with broad spectrum coverage against Neisseria gonorrhoeae |
| 磷酸戊糖途径保护大肠杆菌免受抗生素致死性影响 |
Seregina, T. |
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N/A |
Pentose Phosphate Pathway Protects E. coli from Antibiotic Lethality |
| 通过小标签人工细菌E3连接酶进行蛋白质降解 |
Warming, S. |
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N/A |
Protein degradation by small tag artificial bacterial E3 ligase |
| 欧洲森林虫害爆发概率：基于六种森林昆虫特征校准的通用模型 |
COLLOT, D. |
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Probability of outbreaks of forest insects in Europe: a generic model calibrated on six forest insect profiles |
| 地中海中的海蜇（Rhopilema nomadica）：分子证据支持其迁移，并提出关于其扩散的生态假说 |
Kuplik, Z. |
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Rhopilema nomadica in the Mediterranean: molecular evidence for migration and ecological hypothesis regarding its proliferation |
| 重组塑造了wtf减数分裂驱动因子的多样化 |
Wang, Y. |
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Recombination shapes the diversification of the wtf meiotic drivers |
| 探索新天地：印度谷子苋的成功适应与基因组完整性 |
Singh, A. |
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Going New Places: Successful Adaptation and Genomic Integrity of Grain Amaranth in India |
| 雾化及静脉注射酶替代疗法对黏多糖贮积症II型小鼠的治疗效果 |
Shamoun, A. J. |
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N/A |
Nebulized and intravenous enzyme replacement therapy in mice with mucopolysaccharidosis type II |
| 通过HiCapR技术映射HIV-1 RNA结构、同源二聚体、长程相互作用及持久性结构域 |
Zhang, Y. |
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N/A |
Mapping HIV-1 RNA Structure, Homodimers, Long-Range Interactions and persistent domains by HiCapR |
| 在鼠属中，TCRα和TCRβ位点的独特进化 |
Peters, M. A. |
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Distinct evolution at TCRα and TCRβ loci in the genus Mus |
| 在Lachenalia植物中发现的新型Phenuivirus种揭示了5'和3' RNA序列基序之间可能的共同进化 |
Dekker, R. J. |
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Discovery of a new Phenuivirus species in Lachenalia plants reveals possible co-evolution between 5' and 3' RNA sequence motifs |
| 早期生活中肠道移动组的动态变化及决定因素 |
Fernandez-Pato, A. |
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N/A |
Dynamics and determinants of the gut mobilome in early life |
| 一种新型机制：胞内铁载体结合的铁离子被线粒体摄取，并在其内部还原为亚铁离子 |
Dutta, A. |
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A novel mechanism for the uptake of enterobactin-chelated ferric ions by the mitochondria and subsequent reduction to ferrous ions inside |
| 结构蛋白质组学揭示了孕酮受体的顺序启动机制 |
Mann, M. D. |
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Structural proteomics defines a sequential priming mechanism for the progesterone receptor |
| 呼吸复合物I中喹啉阴离子的催化相关性在生物能量转换中的作用 |
Zdorevskyi, O. |
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Catalytic relevance of quinol anion in biological energy conversion by respiratory complex I |
| RepeatParam：重复蛋白质参数化算法及重复蛋白质结构分析 |
Pretorius, D. |
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RepeatParam: Algorithm for Parameterising Repeat Proteins and Analysis of Repeat Protein Architectures |
| sTREM2的柔性茎域调节其与大脑中磷脂的相互作用 |
Saeb, D. |
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The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain |
| 优化合成血管移植物力学行为的计算框架 |
Jiang, D. |
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N/A |
A Computational Framework to Optimize the Mechanical Behavior of Synthetic Vascular Grafts |
| 乙酸和优化硝酸盐水平对Chlorella Sorokiniana混合营养生长及蛋白质动态的影响 |
Chen, S. |
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Impact of Acetate and Optimized Nitrate Levels on Mixotrophic Growth and Protein Dynamics in Chlorella Sorokiniana |
| 使用多维逆运动学与平均分段形态学评估临床评估中的关节角度数据。 |
Taitano, R. I. |
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Evaluating Joint Angle Data for Clinical Assessment Using Multidimensional Inverse Kinematics with Average Segment Morphometry. |
| 非侵入性细胞膜电位测量的建模：LTSpice仿真与机器学习分析 |
Ma, X. |
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Modeling of Non-invasive Cell Membrane Potential Measurement: LTSpice Simulation and Machine Learning Analysis |
| 通过整合小角散射与AlphaFold解析膜蛋白的构象集合 |
Lidbrink, S. E. |
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N/A |
Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold |
| 表达、纯化及表征大肠杆菌中的二酰化Lipo-YcjN |
Trevino, M. A. |
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Expression, purification, and characterization of diacylated Lipo-YcjN from Escherichia coli |
| 协调端粒脱氧核苷酸转移酶dUTP缺口末端标记（TUNEL）与多重迭代免疫荧光技术，能够丰富细胞死亡的空间背景信息。 |
Sherman, M. S. |
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Harmonizing terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) with multiplexed iterative immunofluorescence enriches spatial contextualization of cell death |
| 根际细菌能促进防御和营养反应的激活，从而抑制大麦上的蚜虫种群。 |
Mbaluto, C. |
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Rhizobacteria prime the activation of defence and nutritional responses to suppress aphid populations on barley |
| 使用综合多组学方法识别的产科综合征之间的胎盘网络差异 |
Piekos, S. N. |
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N/A |
Placental Network Differences Among Obstetric Syndromes Identified With An Integrated Multiomics Approach |
| 通过数学模型理解药物诱导的耐药性 |
Sontag, E. D. |
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N/A |
Understanding therapeutic tolerance through a mathematical model of drug-induced resistance |
| 一种可推广的脑形态异常检测规范深度自编码器：应用于双相情感障碍多站点StratiBip数据集的外部验证框架。 |
Sampaio, I. W. |
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A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework. |
| 识别分子梯度塑造视觉运动转换的突触特异性 |
Dombrovski, M. |
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Gradients of Recognition Molecules Shape Synaptic Specificity of a Visuomotor Transformation |
| 多发性硬化症中克隆扩增的CD8+ T细胞的抗原特异性 |
Mittl, K. |
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Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis |
| 基于病毒样颗粒的疫苗，针对按蚊唾液蛋白TRIO |
Francian, A. |
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N/A |
Virus-like particle-based vaccines targeting the Anopheles mosquito salivary protein, TRIO |
| 异种花粉转移如何影响两种密切相关植物物种的协同进化和共存？ |
Morita, K. |
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How can interspecific pollen transfer affect the coevolution and coexistence of two closely related plant species? |
| 在白面卷尾猴（Cebus imitator）中，MHC异质性可能提高从属雄性而非阿尔法雄性的生育成功率。 |
Buckner, J. C. |
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MHC heterozygosity may increase subordinate but not alpha male siring success in white-faced capuchin monkeys (Cebus imitator) |
| 端粒到端粒的非洲野生稻（Oryza longistaminata）参考基因组揭示了片段和结构变异 |
Guang, X. |
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Telomere-to-telomere African wild rice (Oryza longistaminata) reference genome reveals segmental and structural variation |
| 人类和蝙蝠基因组在COSMIC突变特征下的稳健性 |
Song, J.-H. |
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Human and bats genome robustness under COSMIC mutational signatures |
| 信息论：评估基因组人工智能的框架 |
Robson, E. S. |
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N/A |
Enformation Theory: A Framework for Evaluating Genomic AI |
| 活体哺乳动物大脑的光学透明化 |
Talei Franzesi, G. |
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N/A |
In Vivo Optical Clearing of Mammalian Brain |
| Metapipeline-DNA：一个全面的种系与体细胞基因组学Nextflow管道 |
Patel, Y. |
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N/A |
Metapipeline-DNA: A Comprehensive Germline & Somatic Genomics Nextflow Pipeline |
| 蛋白质设计档案（PDA）：40年蛋白质设计的洞见 |
Chronowska, M. |
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N/A |
The Protein Design Archive (PDA): insights from 40 years of protein design |
| 利用深度学习预测非编码突变对单细胞DNA甲基化的影响 |
Liu, Z. |
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N/A |
Predicting the effect of non-coding mutations on single-cell DNA methylation using deep learning |
| DDGemb：利用嵌入和深度学习预测蛋白质在单点和多点变异下的稳定性变化 |
Savojardo, C. |
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N/A |
DDGemb: predicting protein stability change upon single- and multi-point variations with embeddings and deep learning |
| 建模如何由片状伪足驱动的细胞维持持续迁移并与外部障碍物相互作用 |
Sadhukhan, S. |
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N/A |
Modelling how lamellipodia-driven cells maintain persistent migration and interact with external barriers |
| 通过高分辨率原子力显微镜进行动质体DNA的多尺度拓扑分析 |
Diggines, B. |
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N/A |
Multiscale topological analysis of kinetoplast DNA via high-resolution AFM |
| 蛋白质亚基中的可切换构象：揭示二十面体病毒的组装动力学 |
Li, S. |
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N/A |
Switchable Conformation in Protein Subunits: Unveiling Assembly Dynamics of Icosahedral Viruses |
| 一种介导免疫摧毁衰老癌细胞的抗生素 |
Casagrande Raffi, G. |
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N/A |
An antibiotic that mediates immune destruction of senescent cancer cells |
| 基于代理与连续模型在细胞种群建模中的等价性。应用于微流控装置中胶质母细胞瘤的演化 |
Arroyo-Vazquez, R. B. |
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N/A |
On the equivalence between Agent-Based and Continuum models for cell population modeling. Application to glioblastoma evolution in microfluidic devices |
| 泊洛沙姆188在肌营养不良性心肌病中的差异有效性揭示了复杂的病理生理机制。 |
Heitzman, J. |
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N/A |
Differential Effectiveness of Poloxamer 188 in Dystrophic Cardiomyopathy Reveals Complex Pathophysiology. |
| 拟南芥RS2Z32和RS2Z33蛋白是动态剪接因子，其RNA识别基序（RRM）域有助于蛋白质-蛋白质和蛋白质-RNA相互作用。 |
Fanara, S. |
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N/A |
The Arabidopsis RS2Z32 and RS2Z33 proteins are dynamic splicing factors whose RNA recognition motif (RRM) domain contributes to protein-protein and protein-RNA interactions |
| 心律失常的神经表征：预测编码视角 |
Reinfeld, P. |
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N/A |
Neural Representations of Extrasystoles: A Predictive Coding Perspective |
| 机械渗透信号控制着多能干细胞中的染色质状态和命运转变 |
McCreery, K. P. |
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N/A |
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells |
| 通过田间试验欧洲网络的元分析，在春二棱大麦中发现了新的位点和候选基因 |
Montardit-Tarda, F. |
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N/A |
New loci and candidate genes in spring two-rowed barley detected through meta-analysis of a field trial European network |
| 阿米巴虫属（Amoebophrya sp.）源自卡洛迪尼姆藻（Karlodinium veneficum）的核与线粒体基因组 |
DeMontigny, W. |
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N/A |
The Nuclear and Mitochondrial Genomes of Amoebophrya sp. ex Karlodinium veneficum |
| Grb2磷酸化通过干扰凝聚物的组装，拮抗EGFR驱动的Ras激活。 |
Phan, H. T. |
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N/A |
Grb2 Phosphorylation Antagonizes EGFR-driven Ras Activation by Interfering with Condensate Assembly |