| 局部矿物稳态的变化促进了良性和恶性睾丸微钙化的形成。 |
Boisen, I. M. |
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N/A |
Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications |
| 在概率奖励学习过程中，通过小鼠内侧前额叶皮层进行的变化点估计 |
Murphy, C. E. |
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N/A |
Change point estimation by the mouse medial frontal cortex during probabilistic reward learning |
| 基于大肠杆菌的细胞无细胞系统中的代谢扰动揭示了转录与翻译之间的权衡关系 |
Kapasiawala, M. |
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N/A |
Metabolic perturbations to an E. coli-based cell-free system reveal a trade-off between transcription and translation |
| 贝阿特丽斯：使用深度变分推断从摘要数据进行贝叶斯精细定位 |
Ghosal, S. |
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N/A |
BEATRICE: Bayesian Fine-mapping from Summary Datausing Deep Variational Inference |
| 如果……会怎样？小脑皮质颗粒层的计算解剖学 |
Gilbert, M. |
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N/A |
What if...? Computational anatomy in the granular layer of the cerebellar cortex |
| 对费氏弧菌中环二鸟苷酸调节蛋白的功能分析 |
Isenberg, R. Y. |
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N/A |
Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri |
| 大脑在多步骤预测过程中，会分层次地表征过去和未来。 |
Tarder-Stoll, H. |
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N/A |
The brain hierarchically represents the past and future during multistep anticipation |
| 体质人类学研究中主成分分析（PCA）的偏见需要重新评估进化见解 |
Mohseni, N. |
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N/A |
Biases of Principal Component Analysis (PCA) in Physical Anthropology Studies Require a Reevaluation of Evolutionary Insights |
| 早期生活逆境对压力反应性的性别特异性和发育影响可通过出生后敲低5-HT1A自身受体得到挽救 |
Dixon, R. |
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Sex-specific and Developmental Effects of Early Life Adversity on Stress Reactivity are Rescued by Postnatal Knockdown of 5-HT1A Autoreceptors |
| APP调控因子RHBDL4的丢失在阿尔茨海默病小鼠模型中保护了记忆。 |
Penalva, Y. C. M. |
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Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model. |
| 膜泡可以通过船蛆的可培养胞内共生体Teredinibacter turnerae促进纤维素降解。 |
Gasser, M. T. |
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Membrane vesicles can contribute to cellulose degradation by Teredinibacter turnerae, a cultivable intracellular endosymbiont of shipworms |
| 虚拟现实课堂中的选择性注意与听觉干扰敏感性：AD(H)D成人与非AD(H)D成人的比较 |
Levy, O. |
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N/A |
Selective attention and sensitivity to auditory disturbances in a virtually-real Classroom: Comparison of adults with and without AD(H)D |
| 藤蔓衰退病对西瓜果实氨基酸代谢的影响 |
Santo, H. |
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N/A |
Influence of vine decline disease on the amino acid metabolism of watermelon fruit |
| 先前未测量的遗传多样性解释了基于k-mer的112种植物物种元分析中莱文廷悖论的部分内容 |
Roberts, M. D. |
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Previously unmeasured genetic diversity explains part of Lewontin's paradox in a k-mer-based meta-analysis of 112 plant species |
| 发育中的高级皮层中，相关自发性活动建立了多感官整合 |
Dwulet, J. M. |
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Correlated spontaneous activity sets up multi-sensory integration in the developing higher-order cortex |
| 组胺干扰了小鼠的早期视觉处理 |
Tripodi, M. |
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N/A |
Histamine interferes with the early visual processing in mice |
| 大型齿鲸种内体型变异的总结 |
McClure, J. |
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N/A |
A summary of intraspecific size variation for large odontocetes |
| 结构蛋白质组学揭示了孕酮受体的顺序启动机制 |
Mann, M. D. |
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N/A |
Structural proteomics defines a sequential priming mechanism for the progesterone receptor |
| 结构稳定性决定了互利共生模型生态系统中的进化稳定性 |
Lurgi, M. |
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N/A |
Structural stability determines evolutionary stability in mutualistic model ecosystems |
| 连接牙冠：分析现代人类后臼齿的形态协变 |
Simkova, P. G. |
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N/A |
Connecting crowns: Analyzing morphological covariation in the modern human postcanine dentition |
| 每个速率类别独立碱基组成的改进似然性系统发育估计：5rf模型 |
Waddell, P. J. |
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An independent base composition of each rate class for improved likelihood-based phylogeny estimation: The 5rf model |
| 穴样蛋白-1和机械应力调控具有促转移作用的小型细胞外囊泡亚群的释放 |
Saquel, C. |
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Caveolin-1 and mechanical stress control the release of a pro-metastatic subpopulation of small extracellular vesicles |
| 单核多组学揭示了皮克氏病和阿尔茨海默病中共享及独特的通路 |
Shi, Z. |
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N/A |
Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease |
| 在小鼠生命全程中，对少突胶质细胞组织和少突胶质细胞生成的全脑图谱分析 |
Xu, Y. K. T. |
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N/A |
Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan |
| 在癫痫和智力障碍的人脑类器官模型中模拟皮层与海马网络功能障碍 |
McCrimmon, C. M. |
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N/A |
Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability |
| 内吞素A1促进GABA能突触后机制的组织，以维持兴奋-抑制平衡 |
Chen, X. |
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Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance |
| 一种依赖于多巴胺的机制，用于奖励诱导的恐惧记忆的修改 |
Kong, M.-S. |
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N/A |
A dopamine-dependent mechanism for reward-induced modification of fear memories |
| 典型的突触和神经元特性的发育可以在没有小胶质细胞的情况下进行。 |
O'Keeffe, M. |
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Typical development of synaptic and neuronal properties can proceed without microglia |
| 从Cercis canadensis和Chamaecrista fasciculata基因组推断出的豆科基因组结构和历史 |
Lee, H.-o. |
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N/A |
Legume genome structures and histories inferred from Cercis canadensis and Chamaecrista fasciculata genomes |
| 在100 keV能量下通过单颗粒冷冻电镜确定亚3 Å分辨率的蛋白质结构 |
Karia, D. |
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Sub-3 A resolution protein structure determination by single-particle cryo-EM at 100 keV |
| 未管理蜜蜂群落（Apis mellifera carnica）在森林环境中的蜂群活动率和活动时间 |
Rutschmann, B. |
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N/A |
Swarming rate and timing of unmanaged honeybee colonies (Apis mellifera carnica) in a forest environment |
| 按蚊属物种复合体内味觉受体的分子进化 |
Popkin-Hall, Z. R. |
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N/A |
Molecular Evolution of Gustatory Receptors in the Anopheles gambiae Species Complex |
| detectEVE：在基因组数据中快速、灵敏且精确地检测内源性病毒元素 |
Brait, N. |
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N/A |
detectEVE: fast, sensitive and precise detection of endogenous viral elements in genomic data |
| NetMedPy：一个用于大规模网络医学筛选的Python包 |
Aldana, A. |
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N/A |
NetMedPy: A Python package for Large-Scale Network Medicine Screening |
| 质子结合的变构调节赋予囊泡谷氨酸转运蛋白氯离子活化和谷氨酸选择性 |
Borghans, B. |
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Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters |
| TCV的衣壳蛋白通过泛素化和自噬途径抑制RNA降解，从而促进病毒感染。 |
Wu, K. |
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Coat protein of TCV suppresses RNA decay via ubiquitination and autophagy pathways to facilitate viral infection |
| 全面表征BTK抑制剂的特异性、效力和生物效应：对共价和非共价机制特征的深入见解 |
Darragh, A. C. |
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N/A |
Comprehensive Characterization of BTK Inhibitor Specificity, Potency, and Biological Effects: Insights into Covalent and Non-covalent Mechanistic Signatures |
| 基因组组成预测多倍体蝾螈对环境变化的生理反应 |
Burger, I. |
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Genome composition predicts physiological response to environmental change in polyploid salamanders |
| 叶绿体中磷脂酰肌醇（PPIs）的存在与功能的最新证据 |
Sedaghatmehr, M. |
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New evidence for the presence and function of phosphoinositides (PPIs) in the chloroplast |
| 特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了不同的运动障碍行为 |
Alcacer, C. |
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Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering |
| 使用潜在类线性混合模型改进了间歇性获取两瓶选择大鼠模型中酒精摄入组的分类 |
Angeles-Valdez, D. |
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N/A |
Improved classification of alcohol intake groups in the Intermittent-Access Two-Bottle choice rat model using a latent class linear mixed model |
| 特定特征的区分归一化改进了深度感知中自然图像的编码 |
Ni, L. |
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N/A |
Feature-specific divisive normalization improves natural image encoding for depth perception |
| 通过表观遗传调控与免疫检查点抑制的联合作用增强HBV特异性T细胞反应 |
Urbanek-Quaing, M. |
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N/A |
Enhancing HBV-specific T cell responses through a combination of epigenetic modulation and immune checkpoint inhibition |
| 野生动物的供给选择使宿主中不完全免疫的病原体毒性更高。 |
Walsman, J. C. |
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Wildlife provisioning selects for higher pathogen virulence in hosts with incomplete immunity |
| 杀伤性病毒感染对野生酿酒酵母的适应性影响 |
Unni, R. |
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N/A |
Fitness effects of killer virus infection on wild Saccharomyces paradoxus |
| 利用单粒近红外光谱技术和基因组选择进行表型组选择，以改进玉米育种 |
Prado Graciano, R. |
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N/A |
Integrating Phenomic Selection Using Single-Kernel Near-Infrared Spectroscopy and Genomic Selection for Corn Breeding Improvement |
| 探索破裂的人类股四头肌肌腱在单细胞分辨率下的细胞变化 |
Mimpen, J. Y. |
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N/A |
Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution |
| 模块化光稳定荧光DNA块剖析病原体突变驱动蛋白对集体运输的影响 |
Kita, T. |
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N/A |
Modular photostable fluorescent DNA blocks dissect the effects of pathogenic mutant kinesin on collective transport |
| mRNA密码子序列的深度生成优化，以提高蛋白质产量和治疗效果 |
Li, Y. |
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N/A |
Deep Generative Optimization of mRNA Codon Sequences for Enhanced Protein Production and Therapeutic Efficacy |
| 在蛋白质约束模型中整合混杂酶活性，揭示了地下代谢在代谢表型稳健性中的作用 |
de Moura Ferreira, M. A. |
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N/A |
Integrating promiscuous enzyme activities in protein-constrained models pinpoints the role of underground metabolism in robustness of metabolic phenotypes |
| 二光子驱动的虾青素功能化橙色类胡萝卜素蛋白光保护机制 |
Nizinski, S. |
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N/A |
Two-photon driven photoprotection mechanism in echinenone-functionalized Orange Carotenoid Protein |
| 葡萄糖限制对癌症细胞收缩性的影响：U-87胶质瘤中的阈值反应 |
Kong, A. |
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N/A |
The effect of glucose restriction on cancer cell contractility: A threshold response in U-87 glioma |
| 利用非扩散性邻近标记系统在活细胞和生物体内鉴定目标蛋白质 |
Sun, Y. |
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N/A |
Target protein identification in live cells and organisms with a non-diffusive proximity tagging system |
| InCO的移码突变可能导致日本牵牛花的早花现象，并可能促成了其向北扩张。 |
Katsuyama, H. |
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N/A |
Frame-shift mutation of InCO might cause early flowering of Japanese morning glory and might have contributed to northward expansion |
| 解决珊瑚微生境和礁石生态位中Symbiodiniaceae多样性问题 |
Million, W. |
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N/A |
Resolving Symbiodiniaceae diversity across coral microhabitats and reef niches |
| 成对C型凝集素受体介导秀丽隐杆线虫对不同卵菌病原体的特异性识别。 |
Liu, K. |
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N/A |
Paired C-type lectin receptors mediate specific recognition of divergent oomycete pathogens in C. elegans. |
| 在大量开花期间，地中海果园中管理的熊蜂溢出对生态系统造成了轻微的短期影响。 |
Nachtom Catalan, N. |
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N/A |
Spillover of managed bumble bees from Mediterranean orchards during mass flowering causes minor short-term ecological impacts |
| 通过祖先序列重建研究酶的低温适应性 |
Cui, S. |
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N/A |
Insights into the low-temperature adaptation of an enzyme as studied through ancestral sequence reconstruction |
| DupLoss-2：在基因重复和丢失条件下改进的系统基因组物种树推断 |
Parsons, R. |
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N/A |
DupLoss-2: Improved Phylogenomic Species Tree Inference under Gene Duplication and Loss |
| 鼠标脑提取器：利用全局位置编码和SwinUNETR进行鼠标MRI的脑部分割 |
Kim, Y. |
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N/A |
Mouse Brain Extractor: Brain segmentation of mouse MRI using global positional encoding and SwinUNETR |
| 学生自我调节会调节皮层兴奋性和皮层唤醒的标志物。 |
Weijs, M. L. |
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N/A |
Pupil self-regulation modulates markers of cortical excitability and cortical arousal |
| 电极流形上睡眠慢振荡出现的预测建模：迈向个性化闭环脑刺激 |
Alipour, M. |
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N/A |
Predictive Modeling of Sleep Slow Oscillation Emergence on the electrode manifold: Toward Personalized Closed-Loop Brain Stimulation |
| 一种用于功能性免疫细胞疗法微尺度生产的数字微流控平台 |
Little, S. R. |
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N/A |
A Digital Microfluidic Platform for the Microscale Production of Functional Immune Cell Therapies |
| 一种用于在多重图像中分割细胞和细胞核的新型通道不变架构，采用InstanSeg技术。 |
Goldsborough, T. |
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N/A |
A novel channel invariant architecture for the segmentation of cells and nuclei in multiplexed images using InstanSeg |
| 作物育种中基因组预测的集成方法预测性能的改进 |
Tomura, S. |
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N/A |
Improvements in Prediction Performance of Ensemble Approaches for Genomic Prediction in Crop Breeding |
| 细菌细胞壁的非线性应力软化特性赋予了细胞形状的稳态维持能力。 |
Bardetti, P. |
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N/A |
Non-linear stress-softening of the bacterial cell wall confers cell shape homeostasis |
| 细菌转录抑制因子NrdR - 一种灵活的多因素核苷酸传感器 |
Rozman Grinberg, I. |
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N/A |
Bacterial transcriptional repressor NrdR - a flexiblemultifactorial nucleotide sensor |
| 类似自然语言处理的深度学习辅助在多种细菌中识别和验证硫代磺酸酯耐受性集群 |
Myers, B. K. |
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N/A |
Natural Language Processing-like Deep Learning Aided in Identification and Validation of Thiosulfinate Tolerance Clusters in Diverse Bacteria |
| MYO5B缺陷引起的细胞代谢途径改变和上皮细胞成熟过程可以通过LPAR5激活部分逆转。 |
Momoh, M. |
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N/A |
Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation |
| 刺激重复在初级视觉皮层中引发了一个两阶段的学习过程。 |
Cui, L. |
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N/A |
Stimulus repetition induces a two-stage learning process in primary visual cortex |
| DAR-901和BCG诱导的对抗鸟分枝杆菌的免疫 |
Abate, G. |
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N/A |
Immunity against Mycobacterium avium induced by DAR-901 and BCG |
| 在原核腺苷酸激酶的热适应过程中，灵活性的变化而非紧密性的变化是其基础。 |
Kontopoulos, D. - G. |
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N/A |
Changes in flexibility but not in compactness underlie the thermal adaptation of prokaryotic adenylate kinases |
| 作为治疗囊性纤维化的方法，子宫内全身基因编辑 |
Ricciardi, A. S. |
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N/A |
Systemic in utero gene editing as a treatment for cystic fibrosis |
| NiCo通过微环境协变分析识别细胞状态调控的外在驱动因素 |
Agrawal, A. |
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N/A |
NiCo Identifies Extrinsic Drivers of Cell State Modulation by Niche Covariation Analysis |
| 一种高度活跃的细菌肌动蛋白驱动了另一种对螺旋体游泳运动能力至关重要的同工型的聚合。 |
Takahashi, D. |
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N/A |
A highly active bacterial actin actuates the polymerization of another isoform essential for swimming motility of Spiroplasma |
| 湿度作为昆虫系统昼夜节律同步的时间信号 |
Chen, S.-C. |
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N/A |
Humidity as a zeitgeber for circadian entrainment of insect systems |
| 通过药代动力学模型测量心脏中活体和离体状态下的细胞膜和线粒体膜电位 |
Waters, E. C. |
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N/A |
Sarcolemmal and mitochondrial membrane potentials measured ex vivo and in vivo in the heart by pharmacokinetic modelling of sestamibi |
| 兴奋性氨基酸转运蛋白3底物识别的结构基础 |
Qiu, B. |
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N/A |
Structural basis of the excitatory amino acid transporter 3 substrate recognition |
| 通过时间分辨小角X射线散射捕捉到的G-四链体折叠的早期事件 |
Monsen, R. C. |
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N/A |
Early Events in G-quadruplex Folding Captured by Time-Resolved Small-Angle X-Ray Scattering |
| 平衡运动脊髓回路中的兴奋与抑制 |
Chia, R. |
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N/A |
Balancing Excitation and Inhibition in the Locomotor Spinal Circuits |
| 糖萼生成膜曲率和感知膜曲率的生物物理建模 |
Xiao, K. |
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N/A |
Biophysical modeling of membrane curvature generation and curvature sensing by the glycocalyx |
| 从旋转平均的二维X射线衍射图样中恢复昆虫飞行肌的三维结构 |
Iwamoto, H. |
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N/A |
Restoration of 3-D structure of insect flight muscle from a rotationally averaged 2-D X-ray diffraction pattern |
| 膜辅助Aβ40聚集途径 |
Muhammedkutty, F. N. K. |
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N/A |
Membrane-assisted Aβ40 aggregation pathways |
| 使用多重生物传感器条形码校准基于FRET的生物传感器 |
Wu, J.-W. |
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N/A |
Calibration of FRET-based biosensors using multiplexed biosensor barcoding |
| 利用基于模拟的推理从一维细胞轨迹中估计细胞力学参数 |
Heyn, J. |
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N/A |
Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference |
| 模拟鼻窦粘液清除：活性表面衬里的产液腔内的薄膜流动 |
Desai, N. |
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N/A |
Modelling mucus clearance in sinuses: thin-film flow inside a fluid-producing cavity lined with an active surface |
| 可再生活性物质中的分离、有限时间弹性奇异性和粗化现象 |
Roychowdhury, A. |
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N/A |
Segregation, Finite Time Elastic Singularities and Coarsening in Renewable Active Matter |
| 伴侣介导的异型相分离阻止朊蛋白病理性Y145Stop变体的淀粉样形成 |
Arora, L. |
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N/A |
Chaperone-mediated heterotypic phase separation prevents the amyloid formation of the pathological Y145Stop variant of the prion protein |
| Aquavert：用于微生物垂直游泳的成像和微流体技术 |
Obenshain, H. B. |
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N/A |
Aquavert: Imaging and Microfluidics for Vertical Swimming of Microorganisms |
| 运动持续时间影响运动后血容量增多的程度，但不影响急性高强度间歇运动中促红细胞生成素的反应 |
Tripp, T. R. |
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N/A |
Session duration affects the magnitude of post-exercise hypervolemia but not the erythropoietin response to acute high-intensity interval exercise |
| 精确而非预测：身体所有权错觉作为贝叶斯推理下在线精确适应的结果 |
Novicky, F. |
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N/A |
Precision not prediction: Body-ownership illusion as a consequence of online precision adaptation under Bayesian inference |
| 下一代Cu(II)选择性肽穿梭体可防止Cu(Aβ)诱导的毒性和同种异型海马切片中的小胶质细胞活化 |
Okafor, M. |
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N/A |
Next-generation Cu(II) selective peptide shuttles prevent Cu(Aβ)-induced toxicity and microglial activation in organotypic hippocampal slices |
| 盲人足球运动员的楔前叶/后扣带皮层灰质体积增加 |
Morita, T. |
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N/A |
Gray matter volume increase in the retrosplenial/posterior cingulate cortices of blind soccer players |
| 孟加拉国感染志贺氏菌的幼儿中，O特异性多糖（OSP）特异性功能抗体反应有限 |
Bernshtein, B. |
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Limited O-specific polysaccharide (OSP)-specific functional antibody responses in young children with Shigella infection in Bangladesh |
| 拓扑驱动法发现跨膜蛋白S-棕榈酰化 |
Forrester, M. T. |
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N/A |
Topology-Driven Discovery of Transmembrane Protein S-Palmitoylation |
| 中医药调节心脏微血管内皮细胞在多种损伤模型中的机制：一项全面的系统综述 |
Zhou, H. |
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N/A |
Mechanisms of traditional Chinese medicine in modulating cardiac microvascular endothelial cells in various injury models: A comprehensive systematic review |
| GSK-3β的错误调控通过Shot和Tau导致轴突微管卷曲 |
Voelzmann, A. |
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Mis-regulation of GSK-3β causes axonal microtubule curling through Shot and Tau |
| 损失还是重新分配？一种更好地估计由于人类活动增加而导致的动物分布和数量区域变化的途径 |
Mercker, M. |
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N/A |
Loss or redistribution? A better way of estimating regional changes in animal distribution and numbers caused by increased human activities |
| 推断蜜蜂遗传多样性的长期和短期决定因素：养蜂影响与保护策略 |
Leroy, T. |
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N/A |
Inferring long-term and short-term determinants of genetic diversity in honey bees: Beekeeping impact and conservation strategies |
| 东非和南非人群中高分辨率I类HLA-A、-B和-C的多样性 |
Ndhlovu, Z. |
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N/A |
High Resolution Class I HLA -A, -B, and -C Diversity in Eastern and Southern African Populations |
| 噬菌体L衣壳装饰蛋白的模板化三聚作用 |
Woodbury, B. M. |
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N/A |
Templated trimerization of the phage L decoration protein on capsids |
| 细菌毒素SsdA对单链DNA胞嘧啶脱氨作用的序列上下文无关的结构基础 |
Yin, L. |
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N/A |
Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA |
| 基于表面的与基于体素的有限元头部模型：应变响应的比较分析 |
Zhou, Z. |
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N/A |
Surface-Based vs. Voxel-Based Finite Element Head Models: Comparative Analyses of Strain Responses |
| 孔雀羽毛角蛋白的初步结构 |
Russ, P. |
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N/A |
Feather keratin in Pavo cristatus: A tentative structure |
| 细菌表面的直接接触会引发宿主吞噬体膜的相分离。 |
Bhausaheb, A. J. |
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N/A |
Direct contact of the bacterial surface induces phase separation in the host phagosome membrane |
| 内分泌干扰化学物质非单调剂量反应的潜在机制：系统负反馈调节的干扰 |
Shi, Z. |
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Interference with Systemic Negative Feedback Regulation as a Potential Mechanism for Nonmonotonic Dose-Responses of Endocrine-Disrupting Chemicals |
| 用餐期间进行对话所花费的时间可以预测默认网络功能：来自被动移动感知和fMRI研究的证据。 |
Bhatt, D. |
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Time spent in conversation over meals predicts default network function: Evidence from a passive mobile-sensing and fMRI study. |
| 信心评分数据的信心-噪声信心增强（CNCB）模型 |
Mamassian, P. |
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The Confidence-Noise Confidence-Boost (CNCB) model of confidence rating data |
| TGFβ使类似肺泡的巨噬细胞在TLR2激活后诱导I型干扰素 |
Thomas, S. M. |
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TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation |
| 海滨沉积物中分离放线菌的次级代谢产物生物活性分析 |
Shubhro, K. |
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Bioactivity Analysis of Secondary Metabolites from Actinomycetes' Isolated from Coastal Sediments |
| 呼吸上皮的三维纳米结构揭示了运动纤毛-根丝-线粒体之间的通信轴 |
Vijayakumaran, A. |
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N/A |
3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication |
| Pcbp1 在多能性背景下限制 Oct4 的表达 |
Bakhmet, E. I. |
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Pcbp1 constrains Oct4 expression in the context of pluripotency |
| 人类胰岛素受体外域的深度突变扫描，以指导胰岛素抵抗的精准治疗 |
Aslanzadeh, V. |
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N/A |
Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance |
| 单分子磁镊揭示了TAV2b衍生肽能够解旋并稳定双链RNA |
Rashid, Z. M. |
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Single-molecule magnetic tweezers reveals that TAV2b-derived peptides underwind and stabilize double-stranded RNA |
| 超分子酶-肽凝胶用于局部治疗性生物催化 |
Fuchs, M. |
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Supramolecular Enzyme-Peptide Gels for Localized Therapeutic Biocatalysis |
| AI驱动的耐碱性蛋白质进化及其在大规模生产中的应用 |
Kang, L. |
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N/A |
AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production |
| 基于同步加速器的质子和基于直线加速器电子的超高剂量率照射在急性胃肠道毒性方面存在不一致。 |
Liu, K. |
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N/A |
Discordance in acute gastrointestinal toxicity between synchrotron-based proton and linac-based electron ultra-high dose rate irradiation |
| 在PURE系统中从丙酮酸再生ATP |
Yadav, S. |
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N/A |
ATP Regeneration from Pyruvate in the PURE System |
| 测试免疫计算模型——一项受邀挑战，旨在预测百日咳疫苗接种结果 |
Shinde, P. |
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Putting computational models of immunity to the test - an invited challenge to predict B. pertussis vaccination outcomes |
| 邻近标记技术定义了小鼠和原代人巨噬细胞吞噬体腔的蛋白质组 |
Allsup, B. L. |
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Proximity labeling defines the phagosome lumen proteome of murine and primary human macrophages |
| 一种1型免疫-基质细胞网络介导了疾病耐受性和肠道感染的屏障保护作用 |
Westfall, S. |
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A type 1 immune-stromal cell network mediates disease tolerance and barrier protection against intestinal infection |
| 加拿大原住民传统疗法对伤口感染模拟条件下MRSA浮游和生物膜细菌的抗菌潜力 |
Rieger, C. D. |
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The antimicrobial potential of traditional remedies of Indigenous Peoples from Canada against MRSA planktonic and biofilm bacteria in wound-infection mimetic conditions |
| 对美国犬钩虫感染相关风险因素及苯并咪唑F167Y抗药性标记多态性的研究 |
Jimenez Castro, P. D. |
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Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States |
| 白纹夜蛾（鳞翅目：Hyles lineata）的性别特异性化学感觉基因表达表明气味结合蛋白在寄主植物选择中发挥作用 |
Godfrey, R. K. |
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Sex-specific chemosensory gene expression in the whitelined sphinx moth (Lepidoptera: Hyles lineata) suggests a role for odorant-binding proteins in host plant choice |
| 通过CTCF结合活性的获得和丧失来鉴定有害的非编码变异 |
Tubbs, C. |
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Identifying deleterious noncoding variation through gain and loss of CTCF binding activity |
| 增强子激活来自染色体外DNA中的转座元件 |
Kraft, K. |
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Enhancer activation from transposable elements in extrachromosomal DNA |
| 通过线粒体酶复合物的计算基因组学推进骨髓增生异常综合征的变异表型分析 |
Dong, J. |
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Advancing Variant Phenotyping in Myelodysplastic Syndromes via Computational Genomics of Mitochondrial Enzyme Complexes |
| 依赖二聚化的凝胶状dsDNA凝聚作用是人类cGAS激活的基础 |
Sohn, J. |
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Dimerization-dependent gel-like condensation with dsDNA underpins the activation of human cGAS |
| 机器学习驱动的高精度细胞液滴生物打印优化 |
Shin, J. |
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Machine Learning Driven Optimization for High Precision Cellular Droplet Bioprinting |
| 投影统计 ProST 在线统计评估数据投影分析中的组分离 |
Salem, D. |
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N/A |
Projection Statistics ProST Online statistical assessment of group separation in data projection analysis |
| 通过精确的细胞周期状态映射揭示的细胞身份将数据模式联系起来 |
Alahmari, S. |
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Cell identity revealed by precise cell cycle state mapping links data modalities |
| MYC 与 IIa 类 HDAC 抑制剂联合作用可增强非小细胞肺癌中的线粒体功能障碍 |
Park, J. |
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N/A |
MYC plus class IIa HDAC inhibition potentiates mitochondrial dysfunction in non-small cell lung cancer |
| 基于图曲率的免疫检查点响应生物标志物发现流程 |
Bannon, J. J. |
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A Graph Curvature-Based Pipeline for Discovering Immune Checkpoint Response Biomarkers |
| 结合循环性发热与紫锥菊苷对胰腺癌细胞PANC-1产生协同治疗效果 |
Chen, W.-T. |
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Combination of cycling hyperthermia and Echinacoside creates synergistic curing effect on pancreatic cancer PANC-1 cells |
| 小鼠动脉粥样硬化斑块中细胞的分子和时空特征 |
Hou, P. |
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N/A |
Molecular and spatiotemporal characterization of cells in murine atherosclerotic plaques |
| 额叶异常活动与唤醒水平和行动启动及反应力度相关 |
Klein, F. |
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Aberrant prefrontal activity and arousal level correlate with action initiation and response vigor |
| MIP3α-RelMtb鼻内DNA疫苗在小鼠和猕猴中诱导了反应性T细胞向肺部的浸润。 |
Gordy, J. T. |
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MIP3α-RelMtb intranasal DNA vaccination induces reactive T-cell infiltration into the lungs in mice and macaques |
| 喜马拉雅长尾叶猴的群体遗传学及其分类学意义 |
M R, S. |
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N/A |
Population genetics of Himalayan langurs and its taxonomic implications |
| 全基因组鉴定稳定的RNA-染色质相互作用 |
Wen, X. |
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Genome-wide identification of stable RNA-chromatin interactions |
| 人类增强子体内诱变敏感性图谱 |
Kosicki, M. |
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N/A |
Mutagenesis Sensitivity Mapping of HumanEnhancers In Vivo |
| 三碘甲状腺原氨酸和黄芩素的双重干预双向上调Klotho，减轻老年BALB/c小鼠慢性肾脏病及其并发症 |
Mohanty, S. K. |
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A Dual intervention of Triiodothyronine and Baicalein bi-directionally upregulates Klotho with attenuation of chronic kidney disease and its complications in aged BALB/c mice |
| 使用多种机器学习框架对病毒逃逸语言模型进行系统评估 |
Allman, B. |
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N/A |
A systematic evaluation of the language-of-viral-escape model using multiple machine learning frameworks |
| 增强Vaxign-DL以预测疫苗候选者，加入ESM生成的特征 |
Chen, Y. |
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N/A |
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features |
| 胎鼠在子宫内的脑脊液压力：外部因素对脑室空间施加压力 |
Tsujikawa, K. |
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N/A |
CSF pressure in fetal mice in utero: External factors pressurize the intraventricular space |
| 基于膜的芽殖酵母细胞器应激反应 |
Sheng, P. |
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N/A |
Stress response of membrane-based cell organelles in budding yeast |
| 解析斑马鱼早期胚胎发育过程中细胞特异性转录异质性和可变剪接 |
Lin, X. |
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N/A |
Deciphering the Cell Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish |