| 神经元中异染色质长期丧失后，伴随胶质细胞反应和认知能力下降 |
Newman, A. G. |
PDF |
N/A |
Glial Reactivity and Cognitive Decline Follow Chronic Heterochromatin Loss in Neurons |
| intSDM：一个用于构建可重复性工作流的综合物种分布模型领域的R包 |
Mostert, P. S. |
PDF |
N/A |
intSDM : an R package for building a reproducible workflow for the field of integrated species distribution models |
| 进化上多样化的真菌游动孢子展现出特定的游泳模式，这些模式与其超微结构密切相关。 |
Galindo, L. J. |
PDF |
N/A |
Evolutionarily diverse fungal zoospores show contrasting swimming patterns specific to ultrastructure |
| 海马体中扩展记忆表征的形成 |
Vaidya, S. P. |
PDF |
N/A |
The formation of an expanding memory representation in the hippocampus |
| 突触可塑性的结构影响：突触前连接在E/I共调谐出现中的作用 |
Giannakakis, E. |
PDF |
N/A |
Structural influences on synaptic plasticity: the role of presynaptic connectivity in the emergence of E/I co-tuning |
| 内源性病毒元件构成了个性化癌症疫苗抗原的补充来源。 |
Garde, C. |
PDF |
N/A |
Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines |
| 植入前胚胎放大了压力诱导的精子衍生miRNA含量的变化，以介导跨代表观遗传继承 |
Champroux, A. |
PDF |
N/A |
Preimplantation Embryos Amplify Stress-Induced Changes in Sperm-Derived miRNA Content to Mediate Transgenerational Epigenetic Inheritance |
| 在人类细胞中发现微小RNA衍生的RNA和蛋白质 |
Huang, X. |
PDF |
N/A |
Discovery of microsized RNA-derived RNAs and proteins in human cells |
| 改善焦虑研究：通过多状态总结测量的新方法揭示特质焦虑 |
Varga, Z. K. |
PDF |
N/A |
Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states |
| 脑膜炎症的空间转录组学揭示了邻近脑实质中的炎症基因特征 |
Gadani, S. |
PDF |
N/A |
Spatial Transcriptomics of Meningeal Inflammation Reveals Inflammatory Gene Signatures in Adjacent Brain Parenchyma |
| 硒代半胱氨酸tRNA甲基化促进黑色素瘤转移中氧化应激的抵抗力 |
Nease, L. A. |
PDF |
N/A |
Selenocysteine tRNA methylation promotes oxidative stress resistance in melanoma metastasis |
| 在运动执行和运动规划过程中，控制策略可以根据任务需求进行调整。 |
Orban de Xivry, J.-J. |
PDF |
N/A |
A control policy can be adapted to task demands during both motor execution and motor planning |
| 用于工业碳捕获和利用的大规模培养海洋硅藻的生物反应器微生物组 |
Aalto, N. J. |
PDF |
N/A |
The bioreactor microbiome of mass cultivated marine diatoms for industrial carbon capture and utilization |
| eIF3与高度翻译的mRNA的3'-UTR末端结合 |
Mestre-Fos, S. |
PDF |
N/A |
eIF3 engages with 3'-UTR termini of highly translated mRNAs |
| 低盐度显著改变了海洋基础物种昆布（Saccharina latissima，糖海带）的细菌群落。 |
Schenk, S. |
PDF |
N/A |
Low salinity significantly alters the bacterial community of the marine foundation species Saccharina latissima (sugar kelp) |
| 肌动蛋白动力学调控卵黄囊内脏内胚层细胞中两种不同的内体融合模式 |
Koike, S. |
PDF |
N/A |
Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells |
| 港海豹（Phoca vitulina）的触须空间排列与小鼠（Mus musculus）和大鼠（Rattus norvegicus）的触须排列比较 |
Graff, M. M. |
PDF |
N/A |
Spatial arrangement of the whiskers of harbor seals (Phoca vitulina) compared to whisker arrangements of mice (Mus musculus) and rats (Rattus norvegicus) |
| AKAP/AC纳米域上钙-cAMP振荡的时空协调受一个不连贯前馈环路的调控。 |
Qiao, L. |
PDF |
N/A |
Spatiotemporal orchestration of calcium-cAMP oscillations on AKAP/AC nanodomains is governed by an incoherent feedforward loop |
| 牛磺酸泛基因组揭示了与白头牛脱色素相关的KIT上游的片段重复 |
Milia, S. |
PDF |
N/A |
Taurine pangenome uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle |
| 在Hydra水螅的头再生过程中，Notch信号传导是介导两个模式形成过程所必需的。 |
Steichele, M. |
PDF |
N/A |
Notch-signaling is required for mediating between two pattern forming processes during head regeneration in Hydra polyps |
| 从质量加权浓度分布的矩差推断代谢通量 |
Tuobang, L. |
PDF |
N/A |
Infer metabolic fluxes from moment differences of mass-weighted concentration distributions |
| 在人工耳蜗植入儿童中神经语音跟踪的恢复力和脆弱性 |
Federici, A. |
PDF |
N/A |
Resilience and vulnerability of neural speech tracking in children with cochlear implants |
| 盐度耐受性的昼夜调节：Vigna marina中SOS途径和钠排泄的昼夜调控机制 |
Noda, Y. |
PDF |
N/A |
Diurnal regulation of SOS Pathway and Sodium Excretion Underlying Salinity Tolerance of Vigna marina |
| 果蝇中性别特异性行为的昼夜节律控制 |
Franco, D. L. |
PDF |
N/A |
Circadian control of a sex-specific behaviour in Drosophila |
| 解决二聚体形式的途径将肠杆菌科中的质粒与巨型质粒区分开来。 |
Fournes, F. |
PDF |
N/A |
The pathway to resolve dimeric forms distinguishes plasmids from megaplasmids in Enterobacteriaceae |
| 用于延时摄像机监测昆虫及其花卉环境的一个深度学习流程 |
Bjerge, K. |
PDF |
N/A |
A deep learning pipeline for time-lapse camera monitoring of insects and their floral environments |
| 一种血清素类致幻剂的双受体模型 |
Juliani, A. |
PDF |
N/A |
A dual-receptor model of serotonergic psychedelics |
| 单细胞RNA测序揭示的Wilson病中自然杀伤细胞耗竭预测胆囊炎的预后 |
Jin, Y. |
PDF |
N/A |
NK Cell Exhaustion in Wilson's Disease Revealed by Single-cell RNA Sequencing Predicts the Prognosis of Cholecystitis |
| 前颞区双向连接性的变化反映了多声部音乐中的图形-背景反转 |
Kim, C. H. |
PDF |
N/A |
Bidirectional connectivity changes in the frontotemporal areas reflect figure-ground reversal in multivoiced music |
| 用于纵向微生物组研究的微生物网络推断方法——LUPINE |
Kodikara, S. |
PDF |
N/A |
Microbial network inference for longitudinal microbiome studies with LUPINE |
| 防御反应中小分泌肽信号的比较分析：来自维管植物和非维管植物的见解 |
Lyapina, I. |
PDF |
N/A |
Comparative Analysis of Small Secreted Peptide Signaling during Defense Response: Insights from Vascular and Non-Vascular Plants |
| 人类出生组织产品作为非阿片类药物抑制术后疼痛 |
Zhang, C. |
PDF |
N/A |
Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain |
| 人类皮层下听觉异常检测：一项ABR研究 |
Wetekam, J. |
PDF |
N/A |
Subcortical Auditory Deviance Detection in Humans: An ABR Study |
| 双组分信号决定哪些锈菌分泌的蛋白质被转运到寄主植物细胞中 |
Lawrence, G. J. |
PDF |
N/A |
A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant |
| 来自帕金森病患者iPSCs的LRRK2-G2019S突变衍生的少突胶质前体细胞的单细胞转录组变化 |
Dehestani, M. |
PDF |
N/A |
Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation |
| 一种新出现的PB2-627多态性通过突破哺乳动物和禽类宿主中的ANP32限制，增强了禽流感病毒的大流行潜力。 |
Guo, Y. |
PDF |
N/A |
An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts |
| 年轻鱼类的肖像：从东格陵兰早三叠纪的幼体标本重新描述Pteronisculus gunnari (Nielsen, 1942)，并探讨其对早期辐鳍鱼类个体发育的影响 |
Cavicchini, I. |
PDF |
N/A |
A Portrait of a Young Fish: Redescription of Pteronisculus gunnari (Nielsen, 1942) from a juvenile specimen from the Early Triassic of East Greenland, with implications for ontogenetic development in early actinopterygians |
| 质粒病毒维持能够使细菌种群从感染中恢复，并实现病毒与细菌的共存。 |
Sanchez-Martinez, R. |
PDF |
N/A |
Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence |
| 动物基因组结构的保守性是例外，而非普遍规律。 |
Lewin, T. D. |
PDF |
N/A |
Conservation of animal genome structure is the exception not the rule |
| 厌氧消化共生体中关键功能种群的代谢隔离与特征基因簇 |
Wang, Y. |
PDF |
N/A |
Metabolic Segregation and Characteristic Gene clusters of the Key Functional Populations in Anaerobic Digestion Consortia |
| 重新评估社会排斥的神经相关性：一项使用动脉自旋标记技术的网络球范式复制研究 |
Labek, K. |
PDF |
N/A |
Reassessing the Neural Correlates of Social Exclusion: A Replication Study of the Cyberball Paradigm Using Arterial Spin Labelling |
| 用于日本脑炎和西尼罗病毒的感染性亚基因组扩增子策略 |
Singh, P. P. |
PDF |
N/A |
Infectious subgenomic amplicon strategies for Japanese encephalitis and West Nile viruses |
| 雄性和雌性小鼠分别与同性和异性同类形成了更强的社会性厌恶记忆。 |
Beaver, J. N. |
PDF |
N/A |
Male and female mice respectively form stronger social aversive memories with same and different sex conspecifics |
| 纤维素涂料：一类淀粉样蛋白靶向肽 |
Pedrola, J. A. |
PDF |
N/A |
Fibril Paint: a class of amyloid-targeting peptides |
| 从头设计Ras同工型选择性结合剂 |
Zhang, J. Z. |
PDF |
N/A |
De novo design of Ras isoform selective binders |
| 重新审视假单胞菌质粒的不相容性群组：对R质粒及其复制子的综合分析 |
Nishimura, Y. |
PDF |
N/A |
Incompatibility groups of Pseudomonas plasmids revisited: comprehensive analysis of R-factors and their replicons |
| 在患者层面建模意识障碍揭示了网络对诊断的影响与局部节点参数在预后中的作用 |
Zonca, L. |
PDF |
N/A |
Modeling disorders of consciousness at the patient level reveals the network's influence on the diagnosis vs the local node parameters role in prognosis |
| 基因组变化在同属物种对之间是多样的 |
Francis, W. R. |
PDF |
N/A |
Genomic changes are varied across congeneric species pairs |
| 脂联素信号在调节小鼠对脂肪味觉的反应中起作用。 |
Lin, F. |
PDF |
N/A |
Adiponectin signaling modulates fat taste responsiveness in mice |
| 远程缺血预处理通过CD36介导的吞噬作用减轻跨神经元变性并促进中风恢复。 |
Ju, H. |
PDF |
N/A |
Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis. |
| 威尔姆斯瘤中亚型特异性进化模式及临床相关基因组不稳定性的研究 |
Cresswell, G. D. |
PDF |
N/A |
Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour |
| sTREM2的柔性茎域调节其与脑内磷脂的相互作用 |
Saeb, D. |
PDF |
N/A |
The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain |
| 人类和蝙蝠基因组在COSMIC突变特征下的稳健性 |
Song, J.-H. |
PDF |
N/A |
Human and bats genome robustness under COSMIC mutational signatures |
| 结核分枝杆菌拓扑异构酶I在C端缺失后能量上受到严重影响 |
Balthrop, D. |
PDF |
N/A |
Mycobacterial Topoisomerase I Energetically Suffers From C-Terminal Deletions |
| 促性腺激素细胞具有双重起源，其中大多数在微青春期期间源自垂体干细胞。 |
Sheridan, D. |
PDF |
N/A |
Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. |
| 胞外囊泡通过将ATP合成转运至伪足并激活整合素粘附复合物，调控淋巴管平滑肌瘤细胞的亚稳态表型。 |
Kalvala, A. K. |
PDF |
N/A |
Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes. |
| SAF-A SAP结构域在X染色体失活、转录、剪接和细胞增殖中的作用 |
Sharp, J. A. |
PDF |
N/A |
Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation |
| 三种自闭症谱系障碍亚型及其转录组特征：基于形态学相似性网络的推导 |
Jiang, H. |
PDF |
N/A |
Three Subtypes Of Autism Spectrum Disorder With Transcriptomic Signatures Derived From Morphometric Similarity Networks |
| 胚胎增强子元件的表观遗传启动协调发育基因网络 |
Todd, C. D. |
PDF |
N/A |
Epigenetic priming of embryonic enhancer elements coordinates developmental gene networks |
| 腹侧被盖区多巴胺神经活动与前额叶皮层和海马体中的规则表征同时切换 |
Ding, M. |
PDF |
N/A |
Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus |
| 行为状态和刺激强度调节生长抑素中间神经元在稳定网络活动中的作用 |
Cammarata, C. M. |
PDF |
N/A |
Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity |
| 早期生活压力影响小鼠的癫痫结果 |
Coleman, E. M. |
PDF |
N/A |
Early life stress influences epilepsy outcomes in mice |
| 早期精神病患者灰质和白质中的神经突密度和自由水 |
Van Dyken, P. C. |
PDF |
N/A |
Neurite Density and Free Water in the Gray and White Matter of Early Psychosis Patients |
| 人类小脑中浦肯野细胞树突的非等比扩展及增强的区室化 |
Busch, S. E. |
PDF |
N/A |
Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum |
| 具身视角：角回和楔前叶在自然事件记忆中解码自我 |
Iriye, H. |
PDF |
N/A |
An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events |
| 在发育中的新皮质中，Rbfox1/2/3对转录调节因子和Ptbp1的细胞类型特异性剪接 |
Ruan, X. |
PDF |
N/A |
Cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex |
| 在过去500万年间，气候环境对人类脑容量的影响 |
Nicholson, S. L. |
PDF |
N/A |
Climatic-environmental influences on hominin brain size over the last 5 million years |
| THz电磁场对离子通道影响的模拟协议 |
Xue, L. |
PDF |
N/A |
Protocol for Simulating the Effect of THz Electromagnetic Field on Ion Channels |
| 自闭症谱系障碍的Shank3-/-小鼠模型中前额叶回路功能障碍的发展进程 |
Devienne, G. |
PDF |
N/A |
Developmental progression of prefrontal circuit dysfunction in a Shank3-/- mouse model of autism spectrum disorder |
| TMPRSS6 切割 KCNE1 并在铁超载疾病中引发心律失常 |
Peischard, S. |
PDF |
N/A |
TMPRSS6 cleaves KCNE1 and causes arrhythmias in iron overload disease |
| 生酮干预措施能恢复认知功能并调节阿尔茨海默病小鼠模型中的外周代谢紊乱。 |
M'Bra, P. E. H. |
PDF |
N/A |
Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models |
| 肥大细胞促进结核病病理和易感性 |
Gupta, A. |
PDF |
N/A |
Mast cells promote pathology and susceptibility in tuberculosis |
| HIV-1包膜可变区1中罕见的双半胱氨酸残基与中和逃逸及广谱性发展相关联 |
Hesselman, M. C. |
PDF |
N/A |
Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development |
| 解析TLR4和性别对慢性酒精摄入引起的细胞外囊泡脂质组失调的影响 |
Perpina-Clerigues, C. |
PDF |
N/A |
Unravelling the impact of TLR4 and sex on chronic alcohol consumption-induced lipidome dysregulation in extracellular vesicles |
| Rad18在维持胶质母细胞瘤增殖中的一种非催化功能 |
Benbahouche, N. E.-H. |
PDF |
N/A |
A non-catalytic function for Rad18 in sustaining glioblastoma proliferation |
| 近乎完整的鬃狮蜥（Pogona vitticeps）基因组组装为揭示鬃狮蜥性染色体的起源提供了洞见。 |
Guo, Q. |
PDF |
N/A |
A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes |
| 天堂鱼（Macropodus opercularis）作为情感和认知功能的新型转化模型 |
Varga, Z. K. |
PDF |
N/A |
Paradise fish (Macropodus opercularis) as novel translational model for emotional and cognitive function |
| 通过贝叶斯优化和深度学习实现复杂癌细胞球的高分辨率单细胞分割 |
Mogollon, I. |
PDF |
N/A |
Achieving high-resolution single-cell segmentation in convoluted cancer spheroids via Bayesian optimization and deep-learning |
| 胶质瘤中CD200的耗竭增强了抗肿瘤免疫并诱导了肿瘤排斥 |
Raphael, I. |
PDF |
N/A |
CD200 depletion in glioma enhances antitumor immunity and induces tumor rejection |
| 跨环境与依赖情境的互侵入性下，从菌株频率数据中推断成对相互作用的嵌套推断 |
Le, T. M. T. |
PDF |
N/A |
Nested inference of pairwise interactions from strain frequency data across settings and context-dependent mutual invasibilities |
| 美国东南部两种蚂蚁的行为互动及本地超级蚁群的证据 |
Kanwar, S. |
PDF |
N/A |
Behavioral Interactions in Two Ant Species in The Southeast United States and Evidence for a Native Supercolony |
| 胆固醇在M2簇集和病毒出芽中的作用解析 |
Kolokouris, D. |
PDF |
N/A |
The Role of Cholesterol in M2 Clustering and Viral Budding Explained |
| FGFR2促进对ALK酪氨酸激酶抑制剂的耐药性，其抑制作用与lorlatinib联合使用在治疗表达ALK的神经母细胞瘤中具有协同效应。 |
Pucci, P. |
PDF |
N/A |
FGFR2 promotes resistance to ALK tyrosine kinase inhibitors and its inhibition acts synergistically with lorlatinib in the treatment of ALK-expressing neuroblastoma |
| 分布式学习驱动统计性聋化 |
Luthra, S. |
PDF |
N/A |
Distributional learning drives statistical deafening |
| 解决功能性神经成像中的不一致性：一种可复现的数据驱动多尺度功能图谱，用于典型脑网络 |
Jensen, K. M. |
PDF |
N/A |
Addressing inconsistency in functional neuroimaging: A replicable data-driven multi-scale functional atlas for canonical brain networks |
| 弓形虫细胞周期检查点激酶的特征分析 |
Johnson, M. K. |
PDF |
N/A |
Characterisation of cell cycle checkpoint kinases in Toxoplasma gondii |
| 一些人工智能工具在针对猫传染性腹膜炎病毒（FIPV）主要病毒蛋白酶的某些化合物药物设计中的应用 |
Khan, M. Y. |
PDF |
N/A |
Applications of some artificial intelligence tools in the drug design of some compounds targeting the main viral protease of the Feline Infectious Peritonitis Virus (FIPV) in cats |
| 蝾螈表观遗传时钟提供了对可忽略衰老本质的见解。 |
Haluza, Y. |
PDF |
N/A |
Axolotl epigenetic clocks offer insights into the nature of negligible senescence |
| 染色质重塑因子DEK促进乳腺上皮细胞的增殖，并与H3K27me3表观遗传修饰相关。 |
Johnstone, M. |
PDF |
N/A |
The chromatin remodeler DEK promotes proliferation of mammary epithelium and is associated with H3K27me3 epigenetic modifications |
| 无意义错误的重要性：估计蛋白质合成过程中脱落错误的速率及其影响 |
Cope, A. L. |
PDF |
N/A |
The Importance of Nonsense Errors: Estimating the Rate and Implications of Drop-Off Errors during Protein Synthesis |
| 海洋捕食性蜗牛毒液生产的演化 |
Zancolli, G. |
PDF |
N/A |
Evolution of venom production in marine predatory snails |
| FishPi：一种生物信息学预测工具，用于在斑马鱼中关联piRNA和转座元件 |
Godden, A. M. |
PDF |
N/A |
FishPi: a bioinformatic prediction tool to link piRNA and transposable elements in zebrafish |
| 黑水虻的控制性多配交配：通过数量遗传设计推进育种计划 |
Jensen, K. |
PDF |
N/A |
Controlled and polygynous mating in the black soldier fly: advancing breeding programs through quantitative genetic designs |
| RNA聚合酶II和III招募到snRNA启动子的不同机制的结构见解 |
Shah, S. Z. |
PDF |
N/A |
Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters |
| scDrugAtlas：一个综合性的单细胞药物反应图谱，用于揭示治疗效果中的肿瘤异质性 |
Huang, W. |
PDF |
N/A |
scDrugAtlas: an integrative single-cell drug response atlas for unraveling tumor heterogeneity in therapeutic efficacy |
| 皮肤成纤维细胞异质性的共识单细胞转录组图谱 |
Ascension, A. M. |
PDF |
N/A |
A consensus single-cell transcriptomic atlas of dermal fibroblast heterogeneity |
| 使用Exeter Multiscope自动测量心肌细胞单层收缩 |
Corbett, A. D. |
PDF |
N/A |
Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope |
| LYMTACs：嵌合小分子重新利用溶酶体膜蛋白实现目标蛋白的重新定位与降解 |
Nalawansha, D. A. |
PDF |
N/A |
LYMTACs: Chimeric Small Molecules Repurpose Lysosomal Membrane Proteins for Target Protein Relocalization and Degradation |
| 两种非小细胞肺癌亚型之间转录组和蛋白质组表达的比较分析 |
Nicholas, B. |
PDF |
N/A |
Comparative analysis of transcriptomic and proteomic expression between two non-small cell lung cancer subtypes |
| 赖氨酰氧化酶对小鼠子宫肌层收缩力和及时分娩是必要的 |
Ouellette, A. |
PDF |
N/A |
Lysyl Oxidases are Necessary for Myometrial Contractility and On-Time Parturition in Mice |
| 左心房应变作为压力超负荷小鼠模型中心脏功能障碍的预测因子 |
Salvas, J. P. |
PDF |
N/A |
Left Atrial Strain as a Predictor of Cardiac Dysfunction in a Murine Model of Pressure Overload |
| ERC1的生物分子凝聚招募ATG8和NBR1，驱动自噬小体的形成，以促进植物的热耐受性。 |
Chung, K. K. |
PDF |
N/A |
Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance |
| 尽管四维流磁共振成像（4D flow MRI）中存在非正态误差，心血管数字孪生中的不确定性：识别可靠的生物标志物，如心室舒张率 |
Tunedal, K. |
PDF |
N/A |
Uncertainty in cardiovascular digital twins despite non-normal errors in 4D flow MRI: identifying reliable biomarkers such as ventricular relaxation rate |
| 通过电影驱动的超高场fMRI识别人类和小猕猴大脑网络中的功能同源体 |
Zanini, A. |
PDF |
N/A |
Identifying Functional Homologues in Human and Marmoset Brain Networks via Movie-Driven Ultra-High Field fMRI |
| 啮齿动物连续表现测试中与任务时间相关的性能下降并非由任务中的身体脱离引起。 |
Li, Y. |
PDF |
N/A |
Time-on-task-related decrements in performance in the rodent continuous performance test are not caused by physical disengagement from the task |
| 评估用于人类脊髓非侵入性电生理学的噪声校正方法 |
Bailey, E. |
PDF |
N/A |
Evaluating noise correction approaches for non-invasive electrophysiology of the human spinal cord |
| 任务时间越长，注视漂移增加 |
Friedman, L. |
PDF |
N/A |
Fixation Drift Increases as a Function of Time-on-Task |
| 新近习得的词语-动作关联在运动准备期间触发听觉皮层激活：对动作词语学习中的赫布可塑性的启示 |
Tretyakova, V. |
PDF |
N/A |
Newly Acquired Word-Action Associations Trigger Auditory Cortex Activation During Movement Preparation: Implications for Hebbian Plasticity in Action Words Learning |
| 单侧手部肌肉收缩对内在奖励情境下额叶alpha不对称性和抑制控制的影响：一项随机对照试验 |
Akil, A. M. |
PDF |
N/A |
The effect of unilateral hand muscle contraction on frontal alpha asymmetry and inhibitory control in intrinsic reward contexts, a randomized controlled trial |
| 从视觉皮层活动的动态估计注意力场 |
Bloem, I. M. |
PDF |
N/A |
Dynamic estimation of the attentional field from visual cortical activity |
| 跨突触IgLON黏附分子复合物直接接触并聚集烟碱型受体 |
Mialon, M. |
PDF |
N/A |
A trans-synaptic IgLON adhesion molecular complex directly contacts and clusters a nicotinic receptor |
| β2-肾上腺素能偏向激动剂以NF-κB依赖的方式抑制Th17的发育及记忆Th17细胞的反应。 |
Hajiaghayi, M. |
PDF |
N/A |
β2-Adrenergic Biased Agonist Inhibits the Development of Th17 and the Response of Memory Th17 Cells in an NF-κB-Dependent Manner. |
| 免疫细胞对弥漫性大B细胞淋巴瘤的影响：孟德尔随机化分析 |
He, H. |
PDF |
N/A |
Immune Cell Influence on Diffuse Large B-Cell Lymphoma: A Mendelian Randomization Analysis |
| 通过数字空间分析确定的原发性子宫癌肉瘤中肿瘤间和肿瘤内异质性免疫表现 |
Li, Y. |
PDF |
N/A |
Inter- and intra-tumor heterogeneous immune presentation in primary uterine carcinosarcoma determined by digital spatial profiling |
| 基因编码的FerriTag作为冷冻电子断层扫描的特异性标记 |
Wang, C. |
PDF |
N/A |
Genetically Encoded FerriTag as a Specific Label for Cryo-Electron Tomography |
| 两个世纪以来环境变化中植物-真菌共生现象的日益普遍 |
Fowler, J. C. |
PDF |
N/A |
Increasing prevalence of plant-fungal symbiosis across two centuries of environmental change |
| 生殖干扰能否融入害虫控制的绝育昆虫技术？来自斑翅果蝇Drosophila suzukii的启示 |
Cerasti, F. |
PDF |
N/A |
Can reproductive interference be integrated into the Sterile Insect Technique for pest control? Insights from the spotted wing fly Drosophila suzukii |
| 印度鸟类状况2023：利用半结构化公民科学促进鸟类保护的框架 |
Viswanathan, A. |
PDF |
N/A |
State of India's Birds 2023: A framework to leverage semi-structured citizen science for bird conservation |
| 小鼠属中不同CD8+ α/β-TCR库的遗传决定因素 |
Peters, M. A. |
PDF |
N/A |
Genetic determinants of distinct CD8+ α/β-TCR repertoires in the genus Mus |
| 个人空间与群体灾难中的集体行为 |
Lugo, I. |
PDF |
N/A |
The personal space and the collective behavior of crowd disasters |
| 通过分布匹配实现结构脑连接的协调 |
Zhou, Z. |
PDF |
N/A |
Harmonization of Structural Brain Connectivity through Distribution Matching |
| 靶向聚合物囊泡可增强损伤后外周神经的递送 |
Trumbull, K. |
PDF |
N/A |
Targeted Polymersomes Enable Enhanced Delivery to Peripheral Nerves Post-Injury |
| 一种新型的小鼠前肢生物力学模型在最佳控制模拟的抓取运动中预测肌肉活动 |
Gilmer, J. I. |
PDF |
N/A |
A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements |
| 揭示基于芯片的周围神经系统和中枢神经系统中神经元靶向树枝状聚合物在siRNA递送中的潜力 |
Spencer, A. P. |
PDF |
N/A |
Unveiling the potential of neuron-targeted dendriplexes for siRNA delivery using a PNS-CNS-on-Chip |
| 工程化壳聚糖衍生纳米载体用于高效外周和中枢神经元siRNA递送 |
Spencer, A. P. |
PDF |
N/A |
Engineered chitosan-derived nanocarrier for efficient siRNA delivery to peripheral and central neurons |
| 利用蛋白质生物信息学深入挖掘免疫肽组学数据集 |
Boughter, C. T. |
PDF |
N/A |
Utilizing Protein Bioinformatics to Delve Deeper Into Immunopeptidomic Datasets |
| LLPS REDIFINE 能够对多组分凝聚物进行生物物理特性表征，无需任何标签或标记。 |
Novakovic, M. |
PDF |
N/A |
LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels |
| 恒温动物体温的分子起源 |
Artmann, G. M. |
PDF |
N/A |
The molecular origin of body temperature in homeothermic species |
| 阐明电压门控钠通道中等效门控电荷突变的差异性影响 |
Elhanafy, E. |
PDF |
N/A |
Elucidating the Differential Impacts of Equivalent Gating-Charge Mutations in Voltage-Gated Sodium Channels |
| 致癌驱动突变N642H在STAT5B SH2结构域中的结构影响 |
Haas-Neill, L. |
PDF |
N/A |
The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain |
| 细胞内核磁共振显示，细胞会选择性地放大和结构重塑淀粉样纤维。 |
Ansari, S. |
PDF |
N/A |
In cell NMR reveals cells selectively amplify and structurally remodel amyloid fibrils |
| 探索从热力学稳定和动力学陷阱的枯草杆菌蛋白酶ISP1和SbtE的能量景观的序列和结构决定因素 |
Hood, M. R. |
PDF |
N/A |
Exploring the sequence and structural determinants of the energy landscape from thermodynamically stable and kinetically trapped subtilisins: ISP1 and SbtE |
| 多稳态、吸收边界和生长对图灵模式形成的影响 |
Oliver Huidobro, M. |
PDF |
N/A |
Effects of multistability, absorbing boundaries and growth on Turing pattern formation |
| 在生长诱导压力下，细胞干质量密度增加。 |
Kim, H. |
PDF |
N/A |
Intracellular dry mass density increases under growth-induced pressure |
| 在PET降解酶的共振分配中，操作温度下的核磁共振（NMR） |
Gabrielli, V. |
PDF |
N/A |
NMR at operational temperature for resonance assignments of a PET degrading enzyme |
| Zellweger谱系障碍的PEX1-p.Gly844Asp小鼠模型中视网膜色素上皮结构和脂质变化的地理特征。 |
Omri, S. |
PDF |
N/A |
Geographic characterization of RPE structure and lipid changes in the PEX1-p.Gly844Asp mouse model for Zellweger spectrum disorder. |
| 发现新型1,4-二羰基硫代半缩氨基脲作为DNA促旋酶抑制剂用于治疗耐甲氧西林金黄色葡萄球菌感染 |
Zhang, G. |
PDF |
N/A |
Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection |
| 个体行为表型的漂移作为应对不可预测世界的策略 |
Maloney, R. T. |
PDF |
N/A |
Drift in Individual Behavioral Phenotype as a Strategy for Unpredictable Worlds |
| 在快速眼动睡眠期间，结构化和非结构化的再激活受到新奇体验的调节。 |
Choi, J. |
PDF |
N/A |
Structured and unstructured reactivations during REM sleep are modulated by novel experiences |
| 经过训练的腹侧视觉通路深度神经网络模型能够稳健地编码数量信息，而不受物体和场景身份的影响。 |
Chapalain, T. |
PDF |
N/A |
Trained deep neural network models of the ventral visual pathway encode numerosity with robustness to object and scene identity |
| 小鼠海马中与年龄相关的转录组和表观遗传变化 |
Bilgic, M. |
PDF |
N/A |
Age-associated transcriptomic and epigenetic alterations in mouse hippocampus |
| 高血糖选择性地增加大脑的非氧化葡萄糖消耗，而不影响血流。 |
Blazey, T. |
PDF |
N/A |
Hyperglycemia selectively increases cerebral non-oxidative glucose consumption without affecting blood flow |
| 利用扩散磁共振成像绘制人类未定带的地形组织图 |
Haast, R. A. |
PDF |
N/A |
Mapping the topographic organization of the human zona incerta using diffusion MRI |
| 放射免疫疗法的差异性反应是由肿瘤微环境的内在特征所决定的。 |
Karam, S. D. |
PDF |
N/A |
Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment |
| 硫酸化糖胺聚糖P3R99单克隆抗体的表征及其抗动脉粥样硬化潜力：物理化学和功能性见解 |
Valencia, L. M. |
PDF |
N/A |
Characterization and Antiatherogenic Potential of P3R99 Monoclonal Antibody Against Sulfated Glycosaminoglycans: Physicochemical and Functional Insights |
| 活性EB1激增促进双体嗅觉纤毛生长外段中的微管流入 |
Agarwal, R. G. |
PDF |
N/A |
Active EB1 surges promote tubulin influx into the growing outer segments of the bipartite olfactory cilia in Drosophila |
| 支链氨基酸代谢是细胞衰老的重要调节因子。 |
Aramaki, Y. |
PDF |
N/A |
Branched-chain amino acid metabolism is a crucial modulator of cellular senescence |
| 鉴定新型肌因子及潜在蛋白质靶点，这些因子介导了长期收缩活动诱导的骨骼肌-细胞外囊泡处理后的功能适应 |
Obi, P. O. |
PDF |
N/A |
Identification of novel myokines and putative protein targets that mediate functional adaptations in response to chronic contractile activity induced skeletal muscle-extracellular vesicle treatment |
| 一个流体液滴收集了活细胞中微管收缩所产生的力 |
Morelli, K. |
PDF |
N/A |
A fluid droplet harvests the force generated by shrinking microtubules in living cells |
| 在数据旅程中学到的教训：从实验到预测激酶亲和力、选择性、多靶点药理学和耐药性的模型 |
Lopez-Rios de Castro, R. |
PDF |
N/A |
Lessons learned during the journey of data: from experiment to model for predicting kinase affinity, selectivity, polypharmacology, and resistance |
| 雌性大鼠中存在明显的操作性行为表型及短暂戒断引发的酒精摄入量增加现象 |
Pitock, J. R. |
PDF |
N/A |
Presence of distinct operant phenotypes and transient withdrawal-induced escalation of operant ethanol intake in female rats |
| 胶质细胞会多任务处理以弥补邻近胶质细胞的功能障碍。 |
Beachum, A. N. |
PDF |
N/A |
Glia multitask to compensate for neighboring glial cell dysfunction |
| 将植物来源的化合物芹菜素重新用于抗衰老流程中的衰老效应 |
Zhang, H. |
PDF |
N/A |
Repurposing the plant-derived compound apigenin for senomorphic effect in antiaging pipelines |
| 推算的DNA甲基化在吸烟和生理年龄的关联性上优于测量的位点 |
Richmond, A. |
PDF |
N/A |
Imputed DNA methylation outperforms measured loci associations with smoking and chronological age |
| 工程化生长素诱导的降解子系统以实现对生物体生理的可调节体内控制 |
Vicencio, J. |
PDF |
N/A |
Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology |
| 健康小鼠中的司美格鲁肽给药改变了与压力和动机相关的行为 |
Moreno, A. |
PDF |
N/A |
Semaglutide Administration in Healthy Mice Alters Behaviour Related to Stress and Motivation |
| CD300f免疫受体是一种小胶质细胞组织损伤传感器，并在脑损伤后调节吞噬作用。 |
Negro-Demontel, M. L. |
PDF |
N/A |
CD300f immune receptor is a microglial tissue damage sensor and regulates efferocytosis after brain damage |
| 自身抗原TRIM21（Ro52）在溶细胞死亡后组装促炎性免疫复合物 |
Jones, E. L. |
PDF |
N/A |
Autoantigen TRIM21 (Ro52) assembles pro-inflammatory immune complexes following lytic cell death |
| 利用知识图谱理解生态系统：以高致病性禽流感为例的应用 |
Robertson, H. |
PDF |
N/A |
Understanding Ecological Systems Using Knowledge Graphs: An Application to Highly Pathogenic Avian Influenza |
| 无血清食品级和复杂培养基生产对培养肉的环境影响 |
Takenaka, N. |
PDF |
N/A |
Environmental Impacts of Serum-free Food-grade and Complex Culture Medium Production for Cultivated Meat |
| 海洋储库中生物碳的滞留时间和遗留效应 |
Visser, A. W. |
PDF |
N/A |
Residence Times and Legacy of Biogenic Carbon in Ocean Reservoirs |
| 用于乙二醇同化的合成代谢途径优于天然途径 |
Feigis, M. |
PDF |
N/A |
Synthetic metabolic pathways for ethylene glycol assimilation outperform natural counterparts |
| 测量人体胸主动脉及主动脉夹层模型中由磁共振弹性成像导出的硬度的可行性研究 |
Hirad, A. A. |
PDF |
N/A |
Feasibility of Measuring Magnetic Resonance Elastography-derived Stiffness in Human Thoracic Aorta and Aortic Dissection Phantoms |
| 高眼压对筛板氧合的影响：一项关于猴子的实验-计算联合研究 |
Lu, Y. |
PDF |
N/A |
Impact of elevated IOP on lamina cribrosa oxygenation; A combined experimental-computational study on monkeys |
| 比较软组织的连续体模型和直接纤维模型。一个眼生物力学的例子揭示了连续体模型可能会在组织和纤维层面人为地破坏应变。 |
He, X. |
PDF |
N/A |
Comparing continuum and direct fiber models of soft tissues.An ocular biomechanics example reveals that continuum models may artificially disrupt the strains at both the tissue and fiber levels |
| FAIR数据点填充器：协作的FAIR化与FAIR数据点的填充 |
Wijnbergen, D. |
PDF |
N/A |
The FAIR Data Point Populator: collaborative FAIRification and population of FAIR Data Points |
| 基于云的大规模蛋白质组学队列可扩展分析 |
Guturu, H. |
PDF |
N/A |
Cloud-enabled Scalable Analysis of Large Proteomics Cohorts |
| 脂肪细胞前体是乳腺腺体突然退化后维持的受损上皮微环境的主要贡献者。 |
Joshi, P. A. |
PDF |
N/A |
Adipocyte progenitors are primary contributors to the disrupted epithelial niche that is sustained following abrupt mammary gland involution |
| 在表达α-平滑肌肌动蛋白的细胞中敲除LRP6，能阻断博莱霉素诱导的肺损伤后的肺部炎症和纤维化。 |
Sung, E.-A. |
PDF |
N/A |
Ablation of LRP6 in alpha-smooth muscle actin-expressing cells abrogates lung inflammation and fibrosis upon bleomycin-induced lung injury |
| 脂肪细胞特异性缺失Dbc1并不能重现健康肥胖表型，但提示其对炎症信号的调控作用 |
Santos, L. |
PDF |
N/A |
Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling |
| 一种生理学启发的混合CPG/反射控制器，适用于自行车模拟，并能推广到步行 |
Severini, G. |
PDF |
N/A |
A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking |
| 在激活周围神经方面，时间干扰刺激与直接千赫兹刺激之间不存在生物物理学上的区别。 |
Opancar, A. |
PDF |
N/A |
There is no Biophysical Distinction between Temporal Interference Stimulation and Direct kHz Stimulation for Actuation of Peripheral Nerves |
| DendroTweaks：一种揭示树突动力学的交互式方法 |
Makarov, R. |
PDF |
N/A |
DendroTweaks: An interactive approach for unraveling dendritic dynamics |
| 利用空间转录组学技术揭示人类阿尔茨海默病大脑中的斑块-胶质细胞生态位 |
Avey, D. R. |
PDF |
N/A |
Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics |
| 心肌肌球蛋白复合物的神经符号混合模型从其遗传编码中解码可遗传心脏病的结构基础 |
Burghardt, T. P. |
PDF |
N/A |
Neural-symbolic hybrid model for myosin complex in cardiac ventriculum decodes structural bases for inheritable heart disease from its genetic encoding |
| 一种用于高度稀疏、高维、成分数据集的半参数多重插补方法 |
Sohn, M. B. |
PDF |
N/A |
A semi-parametric multiple imputation method for high-sparse, high-dimensional, compositional data |
| 用于fNIRS脑状态分类的黎曼几何 |
Näher, T. |
PDF |
N/A |
Riemannian Geometry for the Classification of Brain States with fNIRS |
| 利用4D Flow MRI-CFD联合框架研究主动脉瓣狭窄引起的心血管血流模式 |
Wang, T. |
PDF |
N/A |
Investigation of hemodynamic bulk flow patterns caused by aortic stenosis using a combined 4D Flow MRI-CFD framework |
| 视网膜筛板和胶质层中星形胶质细胞的形态学比较 |
Waxman, S. |
PDF |
N/A |
Morphological comparison of astrocytes in the lamina cribrosa and glial lamina |
| 用于电刺激大脑的喷墨打印透明电极 |
Matta, R. |
PDF |
N/A |
Inkjet-printed transparent electrodes for electrical brain stimulation |
| SARS-CoV-2主蛋白酶活性位点环的构象空间由配体结合和蛋白质间别构效应决定。 |
Lee, E. |
PDF |
N/A |
The Conformational Space of the SARS-CoV-2 Main Protease Active Site Loops is Determined by Ligand Binding and Interprotomer Allostery |
| 果蝇母体向合子过渡期间先锋因子结合动力学的批量级图谱 |
Dima, S. S. |
PDF |
N/A |
Bulk-level maps of pioneer factor binding dynamics during Drosophila maternal-to-zygotic transition |
| 莱姆病螺旋体的跨内皮迁移涉及通过涉及Cdc42和Rac1的跨细胞途径作为中间步骤的螺旋体内化过程。 |
Alvarez-Olmedo, D. |
PDF |
N/A |
Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1 |
| 全生物体的外部微生物组调节了内部共生体的适应性。 |
Imchen, M. |
PDF |
N/A |
The holobiont's extracellular microbiome modulates the adaptation of an intracellular endosymbiont |
| 在铜绿假单胞菌中，体内暴露于头孢他啶/阿维巴坦后导致对头孢洛扎/他唑巴坦和亚胺培南/西司他丁/瑞来巴坦耐药的突变 |
Rapsinski, G. J. |
PDF |
N/A |
Mutations Leading to Ceftolozane/Tazobactam and Imipenem/Cilastatin/Relebactam Resistance During in vivo exposure to Ceftazidime/Avibactam in Pseudomonas aeruginosa |
| 生物膜粘附蛋白的缺失改变了Desulfovibrio vulgaris Hildenborough的表面附着和细胞策略 |
Pickens, C. P. |
PDF |
N/A |
Absence of biofilm adhesin proteins changes surface attachment and cell strategy for Desulfovibrio vulgaris Hildenborough |
| 生物多样性热点地区的小型哺乳动物携带具有流行潜力的病毒 |
Feng, Y. |
PDF |
N/A |
Small mammals in biodiversity hotspot harbor viruses of epidemic potential |
| 流感病毒A型高效基因组复制需要NS2及规范启动子序列之外的序列 |
Swaminath, S. |
PDF |
N/A |
Efficient genome replication in influenza A virus requires NS2 and sequence beyond the canonical promoter |
| 一个稳定的15成员细菌SynCom在干旱胁迫下促进短柄草的生长 |
Yadav, A. |
PDF |
N/A |
A stable 15-member bacterial SynCom promotes Brachypodium growth under drought stress |
| 转录因子Traffic jam在果蝇卵巢中调控体细胞piRNA通路 |
Brasset, E. |
PDF |
N/A |
The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries |
| 依赖ATP的染色质凝聚物重塑揭示了两种重塑因子不同的中尺度效应 |
Moore, C. M. |
PDF |
N/A |
ATP-dependent remodeling of chromatin condensates uncovers distinct mesoscale effects of two remodelers |
| 肌动蛋白纤维切割和封端的机制：Gelsolin的作用 |
Barrie, K. R. |
PDF |
N/A |
Mechanism of Actin Filament Severing and Capping by Gelsolin |
| 一种用于研究染色质中组蛋白H3的圆形工程化sortase |
Whedon, S. D. |
PDF |
N/A |
A circular engineered sortase for interrogating histone H3 in chromatin |
| 高度迭代回文序列1（HIP1）通过同源依赖和甲基化依赖的方式提高了聚球藻PCC 7002的转化效率 |
Kamoku, C. |
PDF |
N/A |
Highly Iterated Palindrome 1 (HIP1) sequence improves Synechococcus sp. PCC 7002 transformation efficiencies in a homology- and methylation-dependent manner |
| 非洲猪瘟病毒基因MGF_360-4L通过招募线粒体选择性自噬受体SQSTM1降解MDA5，从而抑制干扰素信号传导，对抗先天免疫反应。 |
Niu, Q. |
PDF |
N/A |
The African Swine Fever Virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses |
| 两组分系统ArlRS对金黄色葡萄球菌中壁磷壁酸的糖基开关切换至关重要。 |
Kuijk, M. M. |
PDF |
N/A |
The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus |
| 维多利亚州考拉中重组考拉逆转录病毒（recKoRV）的高频检测表明KoRV的历史整合 |
Legione, A. R. |
PDF |
N/A |
A High Frequency of Detection of Recombinant Koala Retrovirus (recKoRV) in Victorian Koalas Suggests Historic Integration of KoRV |
| 表皮生长因子受体信号调控宿主对侵袭性曲霉病的炎症反应 |
Liu, H. |
PDF |
N/A |
Epidermal Growth Factor Receptor Signaling Governs the Host Inflammatory Response to Invasive Aspergillosis |
| 开发了一种竞争性检测方法，用于评估登革病毒血清型在体外适应性，采用优化的血清型特异性qRT-PCR技术。 |
Griffon, A.-F. |
PDF |
N/A |
Development of a competition assay to assess the in vitro fitness of dengue virus serotypes using an optimized serotype-specific qRT-PCR |
| 探索褐球藻界：描述南大洋沿岸及实验室培养的南极褐球藻群落微生物群 |
Brisbin, M. M. |
PDF |
N/A |
Exploring the Phaeosphere: characterizing the microbiomes of Phaeocystis antarctica colonies from the coastal Southern Ocean and laboratory culture |
| 体内CRISPR筛选鉴定出GRA12作为跨越弓形虫株系和鼠亚种的超越性分泌致病因子 |
Torelli, F. |
PDF |
N/A |
In vivo CRISPR screens identify GRA12 as a transcendent secreted virulence factor across Toxoplasma gondii strains and mouse subspecies |
| 抗病毒机制及金刚烷胺类似物对基于M2 S31N药物抗性流感A病毒的持续抑制作用的临床前评估 |
Tietjen, I. |
PDF |
N/A |
Antiviral Mechanisms and Preclinical Evaluation of Amantadine Analogs that Continue to Inhibit Influenza A Viruses with M2 S31N-Based Drug Resistance |
| 非模式福赛斯坦纳菌基因缺失条件质粒的开发 |
zhou, p. |
PDF |
N/A |
Development of a Conditional Plasmid for Gene Deletion in Non-Model Fusobacterium nucleatum strains |
| 人类CCR4-NOT是一个基因表达的全局调控因子，并且是一种新型逆转录转座子激活的沉默因子。 |
Kulkarni, S. |
PDF |
N/A |
Human CCR4-NOT is a global regulator of gene expression and is a novel silencer of retrotransposon activation |
| EPOP通过直接调节酶复合物二聚化，限制PRC2.1对染色质的靶向作用。 |
Gong, L. |
PDF |
N/A |
EPOP Restricts PRC2.1 Targeting to Chromatin by Directly Modulating Enzyme Complex Dimerization |
| ALX4二聚体的结构和生化特性分析揭示了疾病等位基因如何影响ALX4功能的新见解 |
Cain, B. |
PDF |
N/A |
Structural and biochemical characterization of the ALX4 dimer reveals novel insights into how disease alleles impact ALX4 function |
| 人T细胞白血病病毒的衣壳蛋白是一种潜在的药物靶点。 |
Yu, R. |
PDF |
N/A |
The Human T-cell Leukemia Virus capsid protein is a potential drug target |
| 《小鼠AAV趋向性综合图谱》 |
Walkey, C. J. |
PDF |
N/A |
A Comprehensive Atlas of AAV Tropism in the Mouse |
| 平滑肌Cxcl12激活与流体诱导的肺动脉高压中的血管重塑相关 |
Klouda, T. |
PDF |
N/A |
Smooth muscle Cxcl12 activation is associated with vascular remodeling in flow-induced pulmonary hypertension |
| 真核起始因子eIF4F和eIF4B在闭环形成时促进翻译终止 |
Shuvalova, E. |
PDF |
N/A |
Eukaryotic initiation factors eIF4F and eIF4B promote translation termination upon closed-loop formation |
| 一种雄性精液蛋白SFP-1调控秀丽隐杆线虫雌雄同体交配后的寿命和脂肪代谢 |
Chen, M. |
PDF |
N/A |
A male seminal fluid protein SFP-1 regulates hermaphrodite post-mating longevity and fat metabolism in Caenorhabditis elegans |
| 高北极地区主要由未被充分描述、基因高度多样的噬菌体所主导。 |
Lemieux, A. |
PDF |
N/A |
The High Arctic is dominated by uncharacterized, genetically highly diverse bacteriophages |
| Andexanet alfa在心脏手术中与肝素抵抗的关联：机制与体外视角 |
Chabata, C. V. |
PDF |
N/A |
Andexanet alfa-associated heparin resistance in cardiac surgery: mechanism and in vitro perspectives |
| 映射非特异性过氧化氢酶的选择性氧化 |
Homann, D. |
PDF |
N/A |
Mapping Selective Oxidations of Unspecific Peroxygenases |
| 古DNA阐明了属Ctenomys的模式标本的身份和地理起源 |
Maestri, R. |
PDF |
N/A |
Ancient DNA Clarifies the Identity and Geographic Origin of the holotype of the genus Ctenomys |
| 星形胶质细胞埃兹蛋白定义了小鼠对压力诱导的抑郁行为的恢复力 |
Lin, S.-S. |
PDF |
N/A |
Astrocyte ezrin defines resilience to stress-induced depressive behaviours in mice |
| 食物-肠道轴：新鲜蔬菜叶际病毒群多样且丰富，并能传递至人类肠道病毒群。 |
Park, J.-W. |
PDF |
N/A |
The food-gut axis: the phyllosphere virome of fresh vegetables is diverse, abundant, and transmitted to the human gut virome |
| 人类动脉血管的细胞和转录组图谱 |
Zhao, Q. |
PDF |
N/A |
A cell and transcriptome atlas of the human arterial vasculature |
| Ki67通过调控染色体周边的核脂质积累，促进有丝分裂期间染色体的个体化。 |
Hu, H.-T. |
PDF |
N/A |
Ki67 regulates nuclear lipid accumulation at the chromosomal periphery to facilitate chromosome individualization during mitosis |
| 缺氧和GCM1表达的丧失阻止了人类滋养层干细胞的分化及接触抑制 |
Cinkornpumin, J. K. |
PDF |
N/A |
Hypoxia and loss of GCM1 expression prevents differentiation and contact inhibition in human trophoblast stem cells |
| Robinow综合征DVL1突变在果蝇疾病模型中破坏形态发生和附肢形成 |
Akarsu, G. |
PDF |
N/A |
Robinow Syndrome DVL1 mutations disrupt morphogenesis and appendage formation in a Drosophila disease model |
| 神经内分泌通过果蝇血管微环境调控肠道再生 |
Medina, A. |
PDF |
N/A |
Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila. |
| 急性饮食中蛋氨酸的限制突显了新皮质发育对代谢变化的敏感性。 |
Saha, S. |
PDF |
N/A |
Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations |
| 一罐蠕虫：估算全球蚯蚓物种数量 |
Decaens, T. |
PDF |
N/A |
A can of worms: estimating the global number of earthworm species |
| 开发树皮甲虫鉴定工具的进展 |
Marais, G. C. |
PDF |
N/A |
Progress in Developing a Bark Beetle Identification Tool |
| 草食动物的普遍性在多样化的种植系统中并不能很好地预测产量。 |
Croijmans, L. |
PDF |
N/A |
Herbivore prevalence poorly predicts yield in diverse cropping systems |
| 格陵兰睡鲨（Somniosus microcephalus）的基因组为极端长寿现象提供了新的见解。 |
Sahm, A. |
PDF |
N/A |
The Greenland shark (Somniosus microcephalus) genome provides insights into extremelongevity |
| xCell 2.0：用于细胞类型比例估计的稳健算法，预测免疫检查点阻断反应 |
Angel, A. |
PDF |
N/A |
xCell 2.0: Robust Algorithm for cell type Proportion Estimation Predicts Response to Immune Checkpoint Blockade |
| AlphaFold2 筛选自噬中LC3-LIR相互作用的短线性基序（SLiM） |
Stuke, J. F. M. |
PDF |
N/A |
AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy |
| 通过三维神经胶质重编程生成人类小清蛋白中间神经元 |
Stamouli, C. A. |
PDF |
N/A |
Generating human parvalbumin interneurons through 3D glia reprogramming |
| 系统注射东莨菪碱增加了固定头部小鼠的时间预测变异性。 |
Ujihara, Y. |
PDF |
N/A |
Systemic injection of scopolamine increased the variability of temporal prediction in head-fixed mice. |
| 单细胞基因组和表观基因组共分析揭示了乳腺癌中的硬连线与可塑性 |
Wang, K. |
PDF |
N/A |
Single cell genome and epigenome co-profiling reveals hardwiring and plasticity in breast cancer |