| 紫色叶背植物：气孔分布指标的资源库。 |
Almeida Filho, H. A. |
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N/A |
Plants with purple abaxial leaves: A repository of metrics from stomata distribution. |
| 来自PRPF31+/- hiPSC-RPE的细胞外囊泡中的RNA含量显示出作为视网膜变性生物标志物的潜力 |
Getachew, H. |
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N/A |
The RNA Content of Extracellular Vesicles from PRPF31+/- hiPSC-RPE Show Potential as Biomarkers of Retinal Degeneration |
| 隔离和种间相互作用在产生岛屿哺乳动物辐射的功能多样性中的作用 |
Nations, J. A. |
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N/A |
The roles of isolation and interspecific interaction in generating the functional diversity of an insular mammal radiation |
| 骨骼肌和神经肌肉执行器的Hill型模型：系统性综述 |
Caillet, A. H. |
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N/A |
Hill-type models of skeletal muscle and neuromuscular actuators: a systematic review |
| 基于抑制的视网膜神经节细胞模型：跨物种和刺激的比较与泛化 |
Shahidi, N. |
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N/A |
Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli |
| 大脑中的视觉同质性计算能够解决基于属性的视觉任务。 |
Jacob, G. |
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N/A |
Visual homogeneity computations in the brain enablesolving property-based visual tasks |
| 重温扫视遗漏：扫视引发的模糊是什么样子的 |
Schweitzer, R. |
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N/A |
Saccadic omission revisited: What saccade-induced smear looks like |
| 黄瓜（Cucumis sativus）激酶组：鉴定、注释及对白粉病感染的表达模式 |
Costa, F. C. L. |
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N/A |
The Cucumis sativus kinome: Identification, annotation, and expression patterns in response to powdery mildew infection |
| 快速细胞内酸化是一种由褐飞虱对抗的新型植物防御反应。 |
Jiang, Y. |
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N/A |
Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper |
| 注意通过调整锐化来调节人类对物体的视觉反应 |
Doostani, N. |
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N/A |
Attention Modulates Human Visual Responses to Objects by Tuning Sharpening |
| 改善焦虑研究：通过多状态总结测量的新方法揭示特质焦虑 |
Varga, Z. K. |
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N/A |
Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states |
| 多拷贝基因系统中由遗传漂变驱动的极快进化的悖论 |
Wang, X. |
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N/A |
The paradox of extremely fast evolution driven by genetic drift in multi-copy gene systems |
| M3NetFlow：一种用于综合多组学数据分析的新型多尺度多跳图AI模型 |
Zhang, H. |
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N/A |
M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis |
| 新生成的成年神经元可保护小鼠免受癫痫的侵害。 |
Jain, S. |
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N/A |
Increasing adult-born neurons protects mice from epilepsy. |
| 如果……会怎样？小脑皮层颗粒层的计算解剖学 |
Gilbert, M. |
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N/A |
What if...? Computational anatomy in the granular layer of the cerebellar cortex |
| 铁剥夺吡咯啶对人类机会性病原体的抗菌活性 |
Vollenweider, V. |
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N/A |
Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens |
| STING-CASM-GABARAP通路在溶酶体上激活LRRK2 |
Bentley-DeSousa, A. |
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N/A |
A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes |
| 植物转录因子结合区域发现中的计算方法综合分析 |
Jyoti, |
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N/A |
Comprehensive analysis of computational approaches in plant transcription factors binding regions discovery |
| 糖皮质激素时间药理学揭示了心肌细胞特异性GR-KLF15轴在心脏葡萄糖代谢中的新靶点 |
El Abdellaoui-Soussi, F. |
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N/A |
Glucocorticoid chrono-pharmacology unveils novel targets for the cardiomyocyte-specific GR-KLF15 axis in cardiac glucose metabolism |
| PMP22通过其跨膜结构域与MPZ相关联，破坏这种相互作用会导致功能丧失表型，类似于与压力性麻痹易感性相关的遗传性神经病变（HNPP）。 |
Pashkova, N. |
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N/A |
PMP22 associates with MPZ via their transmembrane domains and disrupting this interaction causes a loss-of-function phenotype similar to hereditary neuropathy associated with liability to pressure palsies (HNPP). |
| 蓝斑微胶质细胞在女性应激反应中的功能作用 |
Smiley, C. E. |
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N/A |
The functional role of locus coeruleus microglia in the female stress response |
| 将梯度提升树应用于QTL定位，并结合Shapley加性解释 |
Ishibashi, T. |
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N/A |
Applying gradient tree boosting to QTL mapping with Shapley additive explanations |
| NF1相关周围神经鞘瘤的综合基因组分析：更新后的生物样本库数据集 |
Banerjee, J. |
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N/A |
Integrated genomic analysis of NF1-associated peripheral nerve sheath tumors: an updated biorepository dataset |
| 猴子外侧前额叶皮层的不同亚区对抽象序列及其组成部分有反应。 |
Rodriguez, N. Y. |
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N/A |
Different subregions of monkey lateral prefrontal cortex respond to abstract sequences and their components |
| 苔藓动物中两侧对称动物基因组的融合、分裂与重组 |
Lewin, T. D. |
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N/A |
Fusion, fission, and scrambling of the bilaterian genome in Bryozoa |
| DC1域蛋白Vacuoleless Gametophytes调控拟南芥雄蕊发育 |
Amigo, N. L. |
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N/A |
The DC1 domain protein Vacuoleless Gametophytes regulates stamen development in Arabidopsis |
| 欧洲濒危睡鼠的单倍体型解析基因组与群体基因组学研究 |
Byerly, P. |
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N/A |
Haplotype-resolved genome and population genomics of the threatened garden dormouse in Europe |
| Syngap1 调控小鼠听觉皮层中 Parvalbumin 阳性中间神经元的突触驱动和膜兴奋性。 |
Francavilla, R. |
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N/A |
Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex |
| MIXL1在人诱导多能干细胞内胚层分化中的激活 |
Osteil, P. |
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N/A |
MIXL1 Activation in Endoderm Differentiation ofHuman Induced Pluripotent Stem Cells |
| FLIGHTED：从噪声高吞吐量实验数据中推断适应性景观 |
Sundar, V. |
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N/A |
FLIGHTED: Inferring Fitness Landscapes from Noisy High-Throughput Experimental Data |
| 噪声模式有助于在噪声中听清声音。 |
Hicks, J. M. |
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N/A |
Noise schemas aid hearing in noise |
| 系统发育对从蛋白质序列数据推断功能区域的影响 |
Dietler, N. |
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N/A |
Impact of phylogeny on the inference of functional sectors from protein sequence data |
| 模拟研究空间在药物敏感与耐药癌细胞相互作用中的作用 |
Pugh, K. |
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N/A |
Simulations probe the role of space in the interplay between drug-sensitive and drug-resistant cancer cells |
| ChatNT：一种用于DNA、RNA和蛋白质任务的多模态对话代理 |
Richard, G. |
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N/A |
ChatNT: A Multimodal Conversational Agent for DNA, RNA and Protein Tasks |
| 海洋深处的光波：对三种海笔（Pennatuloidea，Octocorallia，Anthozoa）发光系统的洞察 |
Duchatelet, L. |
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N/A |
Waves of light at the bottom of the ocean: insights into the luminous systems of three sea pens (Pennatuloidea, Octocorallia, Anthozoa) |
| 基因组语言模型是否足够？探索基因组语言模型在蛋白质下游任务中的应用 |
Boshar, S. |
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N/A |
Are Genomic Language Models All You Need? Exploring Genomic Language Models on Protein Downstream Tasks |
| SaprotHub：让蛋白质建模变得触手可及，惠及所有生物学家 |
Su, J. |
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N/A |
SaprotHub: Making Protein Modeling Accessible to All Biologists |
| 幼鼠卵巢中的三波卵泡发育 |
Yin, Q. |
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N/A |
Three waves of ovarian follicles in juvenile mice |
| BRCA1与非典型DNA结构的相互作用：对基因组维持和疾病机制的见解 |
Lowran, K. |
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N/A |
BRCA1 Interaction with Non-Canonical DNA Structures: Insights into Genome Maintenance and Disease Mechanisms |
| ProTrek：通过三模态对比学习探索蛋白质宇宙 |
Su, J. |
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N/A |
ProTrek: Navigating the Protein Universe through Tri-Modal Contrastive Learning |
| 组成性活化受体ADGRA3信号传导诱导脂肪组织产热 |
Zhao, Z. |
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N/A |
Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis |
| 基于机器学习的多基因预测模型用于鼻咽癌辐射敏感性 |
Li, K. |
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N/A |
A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning |
| 一个调控水稻鞘细胞表达的转录因子五重奏 |
Hua, L. |
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N/A |
A transcription factor quintet orchestrating bundle sheath expression in rice |
| 第三种情景记忆：情景熟悉度是一个与项目熟悉度和回忆不同的过程。 |
Addante, R. J. |
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N/A |
A third kind of episodic memory: Context familiarity is a distinct process from item familiarity and recollection |
| 欧洲外生菌根担子菌纲真菌中宿主选择影响其孢子体积的估算 |
Izumi, H. |
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N/A |
Host selection in European ectomycorrhizal Basidiomycetes affects their estimated spore volumes |
| 通过AI驱动的多参数理性设计增强Taq聚合酶的逆转录酶功能 |
Tomilova, Y. E. |
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N/A |
Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design |
| 基质硬度通过Piezo1介导的TTR活性调节神经元的成熟 |
Kreysing, E. |
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N/A |
Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity |
| 强迫症中的认知序列受到前额叶皮层渐进活动的支持，并由症状严重程度介导。 |
Doyle, H. |
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N/A |
Cognitive sequences in obsessive-compulsive disorder are supported by frontal cortex ramping activity and mediated by symptom severity |
| 质粒病毒维持使细菌种群从感染中恢复并实现病毒-细菌共存 |
Sanchez-Martinez, R. |
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N/A |
Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence |
| CA3中的选择性抑制：通过异突触可塑性实现稳定模式完成的机制 |
Kim, G. |
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N/A |
Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity |
| 敬畏在人类行为和大脑皮层中被描述为一种矛盾的体验：综合虚拟现实-脑电图研究 |
Yi, J. |
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N/A |
Awe is characterized as an ambivalent experience in the human behavior and cortex: integrated virtual reality-electroencephalogram study |
| 发育调控的微外显子缺失对斑马鱼幼体大脑形态和功能的影响微乎其微 |
Calhoun, C. C. S. |
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N/A |
Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function |
| 稻黄斑驳病毒的多模态传播：谷物、贸易与战争的历史与地理溯源 |
Ndikumana, I. |
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N/A |
Grains, trade and war in the multimodal transmission of Rice yellow mottle virus: an historical and phylogeographical retrospective |
| 鞭毛滑动运动：一种新型的独立于推进的机制，用于沙门氏菌和大肠杆菌的表面迁移 |
Panich, J. |
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N/A |
Swashing motility: A novel propulsion-independent mechanism for surface migration in Salmonella and E. coli |
| 编排不可能的化学反应：B12依赖型甲硫氨酸合成酶催化编排的结构快照 |
Mendoza, J. |
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N/A |
Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography |
| 通过尿素激活酶揭示构象动力学与底物结合之间的相互作用：一项单分子FRET研究 |
Scheerer, D. |
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N/A |
Enzyme activation by urea reveals the interplay between conformational dynamics and substrate binding:a single-molecule FRET study |
| 肺炎支原体必需脂蛋白的结构表征 |
Keles, I. |
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N/A |
Structural characterization of an essential lipoprotein of Mycoplasma pneumoniae |
| 在属Mus中TCRα和TCRβ位点的独特进化 |
Peters, M. A. |
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N/A |
Distinct evolution at TCRα and TCRβ loci in the genus Mus |
| 哺乳动物大脑的体内光学透明化 |
Talei Franzesi, G. |
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N/A |
In Vivo Optical Clearing of Mammalian Brain |
| 小说性Pannexin 1异构体在癌症中增加 |
O'Donnell, B. L. |
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N/A |
Novel Pannexin 1 isoform is increased in cancer |
| 小鼠属中不同CD8+ α/β-TCR库的遗传决定因素 |
Peters, M. A. |
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N/A |
Genetic determinants of distinct CD8+ α/β-TCR repertoires in the genus Mus |
| 在健康小鼠中使用Semaglutide给药改变了与压力和动机相关的行为 |
Moreno, A. |
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N/A |
Semaglutide Administration in Healthy Mice Alters Behaviour Related to Stress and Motivation |
| 维多利亚州考拉中重组考拉逆转录病毒（recKoRV）的高频率检测表明KoRV的历史性整合 |
Zheng, L. |
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N/A |
A High Frequency of Detection of Recombinant Koala Retrovirus (recKoRV) in Victorian Koalas Suggests Historic Integration of KoRV |
| 在狒狒群体中，早期哺乳期的同步性高预示着婴儿死亡率增加。 |
Winans, J. C. |
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N/A |
High early lactational synchrony within baboon groups predicts increased infant mortality |
| 可扩展的从元细胞中识别谱系特异性基因调控网络的方法：NetID |
Wang, W. |
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N/A |
Scalable identification of lineage-specific gene regulatory networks from metacells with NetID |
| 斑马鱼ebf3a突变体中感觉系统和大脑皮层的发育障碍 |
Dang, N. D. P. |
PDF |
N/A |
Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant |
| 斑马鱼ebf3a突变体中感觉系统和大脑小脑的发育障碍 |
Dang, N. D. P. |
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N/A |
Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant |
| 在啮齿动物前额叶皮层第2/3层的反复兴奋性突触中，短期易化现象的基础是易于释放的突触囊泡池的逐步充盈。 |
Shin, J. |
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N/A |
Progressive overfilling of readily releasable pool underlies short-term facilitation at recurrent excitatory synapses in layer 2/3 of the rat prefrontal cortex |
| 遗漏响应神经元在听觉皮层中编码负预测误差和概率 |
Yaron, A. |
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N/A |
Omission-responsive neurons encode negative prediction error and probability in the auditory cortex |
| 早期生活神经影像学：皮质区域划分在发育过程中的普遍性 |
Tu, J. |
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N/A |
Early Life Neuroimaging: The Generalizability of Cortical Area Parcellations Across Development |
| 静默视觉言语中的眼球运动追踪未听到的声学信号，并与听觉经验相关联 |
Benz, K. |
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N/A |
Eye Movements in Silent Visual Speech track Unheard Acoustic Signals and Relate to Hearing Experience |
| 基于外部奖励的技能学习对运动可塑性的影响 |
Yadav, G. |
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N/A |
Effects Of Extrinsic Reward Based Skill Learning On Motor Plasticity |
| Shox2对于正常丘脑梭形波功能是必需的。 |
Febbo, I. G. |
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N/A |
Shox2 is necessary for normal thalamic spindle function |
| 课程学习：任务复杂度的顺序获取增强了神经元的辨别能力 |
Shujah, M. |
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N/A |
Curriculum Learning: sequential acquisition of task complexity enhances neuronal discriminability |
| 多表位免疫捕获亨廷顿蛋白揭示纹状体选择性分子特征 |
Justice, J. L. |
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N/A |
Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures |
| 外侧缰核神经元的厌恶编码与行为状态调节 |
Zouridis, I. S. |
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N/A |
Aversion encoding and behavioral state modulation of lateral habenula neurons |
| 通过扫视采样进行物体识别的时空证据积累 |
Zheng, Z. |
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N/A |
Spatiotemporal evidence accumulation through saccadic sampling for object recognition |
| 调控因子的反相聚集塑造基因爆发 |
Li, B. |
PDF |
N/A |
Anti-phase clustering of regulatory factors shapes gene bursting |
| 调控因子的反相聚集塑造了基因爆发 |
Li, B. |
PDF |
N/A |
Anti-phase clustering of regulatory factors shapes gene bursting |
| 自然选择作用于复杂性状，阻碍了多基因评分在古代样本中的预测准确性。 |
Anorve-Garibay, V. |
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N/A |
Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples |
| 高覆盖率、大规模并行单细胞基因组测序与CAP-seq技术 |
Li, M. |
PDF |
N/A |
High-coverage, massively parallel sequencing of single-cell genomes with CAP-seq |
| 缺氧阻碍了颅神经嵴细胞向与颅面发育相关衍生物的分化 |
Schmid, T. |
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N/A |
Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development |
| 多祖先全基因组关联研究揭示了与人类LINE-1和Alu拷贝数变异相关的位点 |
Bravo, J. I. |
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N/A |
Multi-ancestry GWAS reveals loci linked to human variation in LINE-1- and Alu-copy numbers |
| EHZ2抑制增强了铂类化疗在侵袭性前列腺癌变异中的活性 |
Latarani, M. |
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N/A |
EHZ2 inhibition enhances the activity of platinum chemotherapy in aggressive variant prostate cancer |
| 弥合灰质微观结构与功能连接组之间的差距：早产儿与足月婴儿的多模态磁共振成像研究 |
Gondova, A. |
PDF |
N/A |
Bridging the gap between grey-matter microstructural and functional connectomes: A multi-modal MRI study in preterm and full-term infants |
| 通过视觉伽马振荡测量兴奋-抑制平衡的神经发育轨迹 |
Rhodes, N. |
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N/A |
Measuring the neurodevelopmental trajectory of excitatory-inhibitory balance via visual gamma oscillations |
| 如果……？小脑微区中的计算解剖学，小脑网络的中层 |
Gilbert, M. |
PDF |
N/A |
What if...? Computational anatomy in the cerebellar microzone, the middle layer of the cerebellar network |
| 裂解酵母SUMO靶向泛素连接酶Slx8在功能上与核周聚集的着丝粒以及沉默的交配型区域相关联。 |
Chakraborty, S. |
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N/A |
The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery |
| 学习空间转录组学中与表型相关的特征：PASSAGE方法 |
Guo, C.-K. |
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N/A |
Learning phenotype associated signature in spatial transcriptomics with PASSAGE |
| 通过固定化白腐菌混合菌株酶解降解氯酚废水 |
Liu, H. |
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N/A |
Enzymatic Degrading Chlorophenol Wastewater by Mixed Strains of Immobilized White Rot Fungi |
| 结蛋白突变在心肌成纤维细胞中通过beclin-1调节导致TGFβ1介导的病理性纤维化，这是结蛋白心肌病中的一个过程。 |
Chen, H. V. |
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N/A |
Desmoplakin mutations in cardiac fibroblasts cause TGF?1-mediated pathological fibrogenesis in desmoplakin cardiomyopathy via beclin-1 regulation |
| 自然杂草种子捕食者能减少20%的谷物田中因杂草导致的作物产量损失。 |
Muneret, L. |
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N/A |
Natural weed seed predators reduce crop yield loss due to weeds by 20% in cereal fields |
| 在7特斯拉下使用优化的点状编码时间减少与径向采集（PETRA）序列进行超短T2*成像，分别在标准和扩展回波时间下进行。 |
Lockard, C. A. |
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N/A |
Ultrashort-T2* mapping at 7 tesla using an optimized pointwise encoding time reduction with radial acquisition (PETRA) sequence at standard and extended echo times |
| 胆管癌细胞系中的线粒体基因组改变 |
Faipan, A. |
PDF |
N/A |
Mitochondrial genomic alterations in cholangiocarcinoma cell lines |
| Castleman病空间和单细胞图谱揭示关键基质细胞类型和细胞因子通路 |
Smith, D. |
PDF |
N/A |
Spatial and Single Cell Mapping of Castleman Disease Reveals Key Stromal Cell Types and Cytokine Pathways |
| 烟酰胺核苷：通过上调烟酰胺磷酸核糖基转移酶介导的NAD水平，有望成为治疗心肌梗死诱导的急性肾损伤的有效疗法 |
HABEICHI, N. J. |
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N/A |
Nicotinamide riboside: A promising therapy for MI-induced acute kidney injury by upregulating nicotinamide phosphoribosyltransferase-mediated NAD levels |
| 鼻内给予丹曲林纳米颗粒抑制脂多糖诱导的小鼠抑郁和焦虑行为 |
Liu, J. |
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N/A |
Intranasal dantrolene nanoparticles inhibit lipopolysaccharide-induced depression and anxiety behavior in mice |
| 光系统II释放氧气后，能够进展到S1状态的S0状态的重整动力学 |
Boussac, A. |
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N/A |
Kinetics of reformation of an S0 state capable of progressing to an S1 state after the O2 release by Photosystem II |
| 通过Pluronic辅助的同轴3D生物打印技术制备生物工程束状骨骼肌生物执行器 |
Fuentes, J. |
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N/A |
Bioengineering Fascicle-like Skeletal Muscle Bioactuators via Pluronic-Assisted Co-axial 3D Bioprinting |
| 靶向CXCR4与-Pentixather联合使用显著提高小细胞肺癌患者的总体生存率 |
Christensen, K. A. |
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N/A |
Targeting CXCR4 with -Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer |
| EyaHOST是一种模块化的遗传系统，用于研究果蝇（Drosophila melanogaster）中细胞间及肿瘤与宿主之间的相互作用。 |
Teles-Reis, J. |
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N/A |
EyaHOST a modular genetic system for investigation of intercellular and tumor-host interactions in Drosophila melanogaster |
| 学习阅读将语音转换为语音图形表示：来自一项失匹配负波研究的证据 |
Pattamadilok, C. |
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N/A |
Learning to read transforms phonological into phonographic representations: Evidence from a Mismatch Negativity study |
| 具身主体感代理的神经关联 |
Regev Krugwasser, A. |
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N/A |
Neural Correlates of the Embodied Sense of Agency |
| 治疗期间癌症拦截：利用生长动力学创建一个连续变量以评估疾病反应 |
Zhou, M. |
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N/A |
Cancer Interception During Treatment: Using Growth Kinetics to Create a Continuous Variable for Assessing Disease Response |
| KIF5A 调控轴突修复以及 SFPQ 颗粒和线粒体在人类运动神经元中的时间依赖性轴突运输 |
Guerra San Juan, I. |
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N/A |
KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons |
| 瞬时大脑状态参与度的变化在个体发育过程中有所不同，并对执行功能的个体差异产生影响。 |
Ye, J. |
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N/A |
Variation in moment-to-moment brain state engagement changes across development and contributes to individual differences in executive function |
| 通过工程化锌指抑制剂对SCN9A进行强效且特异性的抑制，用于治疗神经性疼痛 |
samie, m. |
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N/A |
Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain |
| 早期NK细胞和T细胞功能障碍标志着肥胖和健康体重患者登革热病情的加重 |
Gregorova, M. |
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N/A |
Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight |
| 在碳青霉烯酶的适应性进化过程中，上位效应推动了多个性状的快速分化。 |
Dabos, L. |
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N/A |
Epistasis drives rapid divergence across multiple traits during the adaptive evolution of a carbapenemase |
| 通过宿主启动的专性外共生和代谢抑制实现早期真核生物起源 |
Krishnan, N. |
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N/A |
Early eukaryogenesis by host-initiated obligate ectosymbiosis and metabolic inhibition |
| 癌症-免疫共进化由抗原突变积累所决定 |
Wang, L. |
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N/A |
Cancer-immune coevolution dictated by antigenic mutation accumulation |
| 通过适应性实验揭示的真菌交配型染色体中的隐性负载 |
Guyot, L. |
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N/A |
Sheltered load in fungal mating-type chromosomes revealed by fitness experiments |
| 微生物群驱动黄粉虫感染结果的性别二态性 |
Seal, S. |
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N/A |
Microbiota drives the sexually dimorphic infection outcomes in mealworm beetles |
| EpipwR：针对连续结果的EWAS的高效功率分析 |
Barth, J. P. |
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N/A |
EpipwR: Efficient Power Analysis for EWAS withContinuous Outcomes |
| 一种模拟人类妊娠期胎盘暴露于环境金属的生物工程模型 |
Fattahi, P. |
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N/A |
A bioengineered model of human placental exposure to environmental metals during pregnancy |
| CryoTEN：利用Transformer高效增强冷冻电镜密度图 |
Selvaraj, J. |
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N/A |
CryoTEN: Efficiently Enhancing Cryo-EM DensityMaps Using Transformers |
| 基于结构的计算分析：胰岛素受体与胰岛素抑制受体之间的相互作用 |
Li, V. |
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N/A |
Structure-Based Computational Analysis of Interactions between Insulin Receptor and Insulin Inhibitory Receptor |
| 发现来自印度南部的一种新的地下鳗鲶新种 |
RAMANATHAN, S. K. |
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N/A |
Discovery of a new species of subterranean eel loach from southern India |
| 味蕾中的死亡：死亡味觉细胞的形态特征及I型细胞的吞噬作用 |
Wilson, C. E. |
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N/A |
Death in the taste bud: Morphological features of dying taste cells and engulfment by Type I cells |
| 神经递质对结构-功能耦合的贡献：来自灰质体积（GMV）和脑熵（BEN）的证据 |
Song, D. |
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N/A |
Neurotransmitters Contribute Structure-Function Coupling: Evidence from Grey Matter Volume (GMV) and Brain Entropy (BEN) |
| 模拟CD8 T细胞衰竭：一种综合方法 |
Manrique-Rincon, A. J. |
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N/A |
Simulating CD8 T Cell Exhaustion: A Comprehensive Approach |
| 关于前向采样方案密度的一个接近紧的下界 |
Kille, B. |
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N/A |
A near-tight lower bound on the density of forward sampling schemes |
| 小鼠多巴胺能穹窿下区神经元的全脑投射 |
Bono, B. S. |
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N/A |
Brain-wide projections of mouse dopaminergic zona incerta neurons |
| 单分子脂质生物传感器减轻内源效应蛋白的抑制作用 |
Holmes, V. |
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N/A |
Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins |
| 优化扩展显微技术揭示了非洲爪蟾卵提取物中物种特异性的纺锤体微管组织 |
Guilloux, G. |
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N/A |
Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts |
| 蛋白质相互作用基序的全蛋白质组依赖性图谱 |
Ambjoern, S. |
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N/A |
A proteome-wide dependency map of protein interaction motifs |
| 造血Tet2失活增强了免疫检查点阻断疗法的反应 |
Vanner, R. J. |
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Hematopoietic Tet2 inactivation enhances the response to checkpoint blockade immunotherapy |
| 卵巢癌中与年龄相关的脂质代谢调控 |
Feng, J. |
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N/A |
Regulation of Age-Related Lipid Metabolism in Ovarian Cancer |
| EB-SUN，果蝇中一种新的微管正端追踪蛋白。 |
Kim, S. K. |
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N/A |
EB-SUN, a New Microtubule Plus-End Tracking Protein in Drosophila. |
| 衰老小鼠各组织的自噬作用 |
Carosi, J. M. |
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N/A |
Autophagy across tissues of aging mice |
| 具有截短的Cas12a结合序列的单链HDR模板提高了在原代人T细胞中的敲入效率 |
Nitulescu, A.-M. |
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N/A |
Single-stranded HDR templates with truncated Cas12a binding sequences improve knock-in efficiencies in primary human T cells |
| 一种在鲍曼不动杆菌中协调肽聚糖周转并激活细胞分裂酰胺酶的保守枢纽蛋白 |
Simpson, B. W. |
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N/A |
A conserved hub protein for coordinating peptidoglycan turnover that activates cell division amidases in Acinetobacter baumannii |
| 一种基于微孔板读取器的高通量方法，用于在没有流式细胞术的情况下监测体外HIV潜伏逆转 |
Nkwelle, C. E. |
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N/A |
A high-throughput, microplate reader-based method to monitor in vitro HIV latency reversal in the absence of flow cytometry |
| 鉴定影响CRISPR相关转座酶的蛋白质以增强基因组编辑 |
Song, L. |
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N/A |
Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing |
| PathMHC：一种工作流程，用于在疫苗靶点识别的发现性免疫肽组学实验中选择性靶向病原体衍生的MHC肽段 |
Leddy, O. |
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N/A |
PathMHC: a workflow to selectively target pathogen-derived MHC peptides in discovery immunopeptidomics experiments for vaccine target identification |
| 延伸因子P调控沙门氏菌抗生素抗性基因的核糖体移码 |
Baek, S. |
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N/A |
Elongation factor P controls ribosomal frameshift of a Salmonella antimicrobial resistance gene |
| 利用果聚糖的γ-变形菌中的SusC/D样蛋白 |
Zuehlke, M.-K. |
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N/A |
SusC/D-like proteins in Gammaproteobacteria that utilize fructans |
| IGF1R在肺炎球菌性肺炎中具有保护作用 |
Felten, M. |
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N/A |
IGF1R is protective in pneumococcal pneumonia |
| SRY-Box转录因子9通过解除转录抑制因子CCAAT/增强子结合蛋白β的抑制作用，调控3'-磷酸腺苷5'-磷酸硫酸合成酶2 mRNA的表达。 |
Liu, C. |
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N/A |
SRY-Box Transcription Factor 9 regulates 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2 mRNA expression through derepression of the transcriptional repressor, CCAAT/enhancer-binding protein beta |
| 基因组方法研究克雷伯氏肺炎杆菌临床分离株中CRISPR/Cas系统与多药耐药性之间的关系 |
Owaid, H. A. |
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N/A |
Genomic approach to studying the relationship between the CRISPR/Cas system and multidrug resistance in clinical isolates of Klebsiella pneumoniae |
| 通过化学标记实现细胞蛋白激酶活性的分子记录 |
Sun, D.-e. |
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N/A |
Molecular recording of cellular protein kinase activity with chemical labeling |
| 单个远端突变通过稳定PET结合增强已知PETase的活性 |
Fu, X. |
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N/A |
Single Distal Mutation Enhances Activity of known PETases via Stabilisation of PET-binding |
| CRISPR编辑影响甲型流感病毒感染的候选宿主因子 |
Kyawe, P. P. |
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N/A |
CRISPR editing of candidate host factors that impact influenza A virus infection |
| 组蛋白甲基转移酶DOT1B对于利什曼原虫（Leishmania mexicana）的阶段分化和巨噬细胞感染并非必需。 |
Eisenhuth, N. |
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N/A |
The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection in Leishmania mexicana |
| 父母照顾对毒蛙皮肤微生物群落组成的影响 |
Fischer, M.-T. |
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N/A |
Effects of parental care on skin microbial community composition in poison frogs |
| 利用病毒RNA加工的阿喀琉斯之踵开发新型抗病毒药物 |
Zahedi Amiri, A. |
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N/A |
Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals |
| 在磷酸盐限制条件下，阿米诺脂的生物合成促进了鲍曼不动杆菌对粘菌素的耐药性。 |
Olea-Ozuna, R. J. |
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N/A |
Aminolipid biosynthesis in response to phosphate limitation promotes colistin tolerance in Acinetobacter baumannii |
| 一项针对挪威肺炎克雷伯菌的全基因组“一个健康”研究揭示了重叠的菌群，但近期在不同宿主间的传播事件较少。 |
Hetland, M. A. K. |
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N/A |
A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs |
| 共生体的丧失和获得，而非共同多样化，塑造了蜜蜂肠道微生物群的多样性和功能。 |
Prasad, A. |
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N/A |
Symbiont loss and gain, rather than co-diversification shapes honeybee gut microbiota diversity and function |
| 预防脑膜炎奈瑟菌鼻咽部定植依赖于抗体调理和中性粒细胞的吞噬作用。 |
Currie, E. G. |
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N/A |
Protection against Neisseria meningitidis nasopharyngeal colonization relies on antibody opsonization and phagocytosis by neutrophils |
| 抗生素诱导的形态变化增强噬菌体捕食：结构化环境中噬菌斑形成的数学模型 |
Bulssico, J. |
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N/A |
Antibiotic-Induced Morphological Changes Enhance Phage Predation: A Mathematical Model of Plaque Formation in Structured Environments |
| flt1失活通过增强内皮细胞活性并限制纤维化反应，促进斑马鱼心脏再生。 |
Wang, Z. |
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N/A |
flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response |
| 多重纳米孔扩增子测序用于区分抗疟药物试验中的复发与新感染 |
Holzschuh, A. |
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N/A |
Multiplexed nanopore amplicon sequencing to distinguish recrudescence from new infection in antimalarial drug trials |
| 工程变体AAV滴定中热稳定性的作用 |
Zin, E. A. |
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N/A |
The Role of Thermal Stability in AAV Titration of Engineered Variants |
| HIV Vpr通过激活一种核仁特异性的ATR途径来降解核仁应激传感器CCDC137 |
Nisson, K. A. |
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N/A |
HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137 |
| 跨膜糖蛋白Gpnmb在斑马鱼心脏再生过程中的免疫和纤维化反应中是必需的。 |
Gupta, S. |
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N/A |
The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration |
| RNA解旋酶HrpA在E. coli中解救碰撞的核糖体 |
Campbell, A. |
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N/A |
The RNA helicase HrpA rescues collided ribosomes in E. coli |
| 尿酸通过天然人URAT1转运的分子机制及其被抗痛风药物抑制的机制 |
Wu, C. |
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N/A |
Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs |
| 不受海马体尖波涟漪调节的前额叶皮质内侧神经元参与空间调谐及即将做出的选择信号传递。 |
den Bakker, H. |
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N/A |
Neurons in the medial prefrontal cortex that are not modulated by hippocampal sharp-wave ripples are involved in spatial tuning and signaling upcoming choice. |
| 小脑-丘脑神经元在学习及小鼠运动技能离线巩固中的多重功能 |
Varani, A. |
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N/A |
Multiple Functions of Cerebello-Thalamic Neurons in Learning and Offline Consolidation of a Motor Skill in mice. |
| 听觉皮层结构与阅读技能的代际传递 |
Kepinska, O. |
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N/A |
Intergenerational transmission of the structure of the auditory cortex and reading skills |
| 斑马鱼模型揭示人类基因SRGAP2在神经胶质细胞和视觉系统发育中的新功能 |
Uribe-Salazar, J. M. |
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N/A |
Zebrafish models of human-duplicated gene SRGAP2 reveal novel functions in microglia and visual system development |
| 高数据率大分子晶体学（HDRMX）的大规模压缩：对衍射数据及后续结构分析的影响 |
Bernstein, H. J. |
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N/A |
Massive Compression for High Data Rate Macromolecular Crystallography (HDRMX): Impact on Diffraction Data and Subsequent Structural Analysis |
| NAPE-PLD基因的缺失在小鼠中引发了情境依赖性的焦虑样行为、应激反应及下丘脑-垂体-肾上腺轴功能的失调。 |
Woodward, T. J. |
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N/A |
Genetic deletion of NAPE-PLD induces context-dependent dysregulation of anxiety-like behaviors, stress responsiveness, and HPA-axis functionality in mice |
| 海马苔藓纤维突触处突触前易化的废除影响神经元集合活动和空间记忆 |
Marneffe, C. |
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N/A |
Abrogation of presynaptic facilitation at hippocampal mossy fiber synapses impacts neural ensemble activity and spatial memory |
| 玩耍行为的转录组在幼年大鼠内侧杏仁核中表现出性别偏向：抑制性神经元的作用 |
Marquardt, A. E. |
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N/A |
The transcriptome of playfulness is sex-biased in the juvenile rat medial amygdala: a role for inhibitory neurons |
| 中性粒细胞特异性STING在心肌缺血/再灌注损伤中的心脏保护作用 |
Brockman, M. L. |
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N/A |
The Cardioprotective Role of Neutrophil-Specific STING in Myocardial Ischemia/Reperfusion Injury |
| Axin1和Axin2调控WNT信号通路，以促进不同的中胚层发育程序 |
Hernandez-Martinez, R. |
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N/A |
Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs |
| IgSF蛋白DIP-α和Dpr10的关键亲和窗口对于适当的运动神经元树突化是必需的。 |
Lopez, D. |
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N/A |
A critical affinity window for IgSF proteins DIP-α and Dpr10 is required for proper motor neuron arborization |
| 将环斑海豹的觅食行为与环境变化联系起来 |
Nykänen, M. |
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N/A |
Linking ringed seal foraging behaviour to environmental variability |
| 广泛存在的自然变异人类外显子有助于遗传学解释 |
Jacobs, H. |
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N/A |
Widespread naturally variable human exons aid genetic interpretation |