| 双色光对神经元的高时间精度激活和抑制 |
Mermet-Joret, N. |
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N/A |
Dual-color optical activation and suppression of neurons with high temporal precision |
| 神经调节器通过在超通道中转移活动流，在递归神经网络中生成多种与上下文相关的行为。 |
Tsuda, B. |
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N/A |
Neuromodulators generate multiple context-relevant behaviors in a recurrent neural network by shifting activity flows in hyperchannels |
| CHAS是一种反卷积工具，用于推断神经和精神疾病的大脑组蛋白乙酰化研究中的细胞类型特异性特征。 |
Murphy, K. B. |
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N/A |
CHAS, a deconvolution tool, infers cell type-specific signatures in bulk brain histone acetylation studies of neurological and psychiatric disorders |
| 健康年轻成人步态控制中认知参与的运动学和神经肌肉特征 |
LANA, V. |
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N/A |
Kinematic and neuromuscular characterization of cognitive involvement in gait control in healthy young adults |
| 骨骼肌和神经肌肉执行器的Hill型模型：系统性综述 |
Caillet, A. H. |
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N/A |
Hill-type models of skeletal muscle and neuromuscular actuators: a systematic review |
| 心形蚌壳通过捆绑的光纤电缆和聚光透镜将阳光传递给共生藻类。 |
McCoy, D. E. |
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N/A |
Heart cockle shells transmit sunlight to photosymbiotic algae using bundled fiber optic cables and condensing lenses |
| PACESS：基于AI的大规模三维骨髓组织图像细胞提取与空间统计 |
Adams, G. |
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N/A |
PACESS: Practical AI-based Cell Extraction and Spatial Statistics for large 3D bone marrow tissue images |
| 使用针电极阵列对糖尿病小纤维周围神经病变进行经皮电生理记录：小鼠和人类的实验研究 |
Blaszkiewicz, M. |
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N/A |
Transdermal Electrophysiological Recordings of Diabetic Small Fiber Peripheral Neuropathy Using a Needle Electrode Array in Mice and Men |
| 小ARF样2 GTP酶TITAN 5与铁调节转运蛋白1的动态调控相关 |
Mohr, I. |
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N/A |
Small ARF-like 2 GTPase TITAN 5 is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER 1 |
| zol & fai：大规模目标基因簇的检测与进化研究 |
Salamzade, R. |
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N/A |
zol & fai: large-scale targeted detection and evolutionary investigation of gene clusters |
| 用于研究果蝇联想学习的驱动线 |
Shuai, Y. |
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N/A |
Driver lines for studying associative learning in Drosophila |
| SARS-CoV-2刺突抗体与登革病毒发生交叉反应，并在体外和体内增强感染 |
Jakhar, K. |
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N/A |
SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in-vitro and in-vivo |
| JointPRS：一种数据自适应框架，用于整合遗传相关性的多群体遗传风险预测 |
Xu, L. |
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N/A |
JointPRS: A Data-Adaptive Framework for Multi-Population Genetic Risk Prediction Incorporating Genetic Correlation |
| 使用基于聚类的排列检验来估计MEG/EEG起始时间：问题有多严重？ |
Rousselet, G. A. |
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N/A |
Using cluster-based permutation tests to estimate MEG/EEG onsets: how bad is it? |
| TIPE通过促进PKM2/HIF-1α轴的糖酵解作用，在黑色素瘤中驱动类似癌症干细胞的表型。 |
Tian, M. |
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N/A |
TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma |
| 流感聚合酶活性位点的高分辨率结构揭示了复制起始类似构型中保守的双碱性基序在PA亚基中的关键作用 |
Cusack, S. |
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N/A |
High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit |
| 人类肌肉中大量运动单位的识别揭示了神经调质输入对速率编码的多样影响 |
Avrillon, S. |
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N/A |
The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding |
| 在单细胞分辨率下通过基因信号模式分析绘制基因空间图谱 |
Venkat, A. |
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N/A |
Mapping the gene space at single-cell resolution with gene signal pattern analysis |
| 在衰老过程中，人类细胞的着丝粒失活是可以被挽救的。 |
Sikder, S. |
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N/A |
Centromere inactivation during aging can be rescued in human cells |
| 肠道与鼻咽微生物群组成之间的关系可以预测COVID-19的严重程度。 |
Martin-Castano, B. |
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N/A |
The relationship between gut and nasopharyngeal microbiome composition can predict the severity of COVID-19 |
| Caspase-2通过杀死具有多余中心体的细胞来发挥作用。 |
Rizzotto, D. |
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N/A |
Caspase-2 kills cells with extra centrosomes |
| 多功能聚合结构域决定了拟南芥中表观遗传沉默的开始 |
Schulten, A. |
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N/A |
Multifunctional polymerization domains determine the onset of epigenetic silencing in Arabidopsis |
| 体积电子显微镜揭示了人死后前额叶皮层的3D突触纳米结构 |
Glausier, J. R. |
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N/A |
Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex |
| 沙门氏菌利用植物免疫系统产生的活性氧物种来增强其定殖能力。 |
Tzpilevich, E. |
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N/A |
Salmonella exploits the reactive oxygen species generated by the plant immune system to enhance colonization |
| 不确定性的多重及特定主题角色在奖励导向决策中的作用 |
Paunov, A. |
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N/A |
Multiple and subject-specific roles of uncertainty in reward-guided decision-making |
| 通过计算允许先前有问题的序列参数的第二种对比度，对基于MP2RAGE的R1映射中的B1+不均匀性容差进行3T研究 |
Ruijters, L. |
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N/A |
A 3T investigation of B1+-inhomogeneity tolerance in MP2RAGE-based R1-mapping by calculating second contrast that permits previously problematic sequence parameters |
| 寒冷诱导脑区选择性细胞活动依赖性脂质代谢 |
Min, H. |
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N/A |
Cold induces brain region-selective cell activity-dependent lipid metabolism |
| 最快和最密集反应的协调体现了老鼠类似人类的反应时间。 |
Kim, C. H. |
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N/A |
Harmonization of the fastest and densest responses embodies the humanlike reaction time of mice |
| 细菌应激颗粒通过排除核糖核酸酶来保护mRNA |
Pei, L. |
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N/A |
Bacterial stress granule protects mRNA through ribonucleases exclusion |
| 前额叶和颞叶区域的双向连接变化反映了多声部音乐中的图形-背景反转 |
Kim, C. H. |
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N/A |
Bidirectional connectivity changes in the frontotemporal areas reflect figure-ground reversal in multivoiced music |
| 未预料到的共价抑制剂和合成配体与PPARγ的共结合机制 |
Shang, J. |
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N/A |
Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARgamma |
| 实验性创伤性脑损伤后海马θ-γ耦合和锋电位场相干性的破坏 |
Adam, C. D. |
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N/A |
Disrupted Hippocampal Theta-Gamma Coupling and Spike-Field Coherence Following Experimental Traumatic Brain Injury |
| 无脊椎动物中Cdk4/6-Cdkn2系统的演化 |
Yuki, S. |
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N/A |
Evolution of the Cdk4/6-Cdkn2 system in invertebrates |
| 昼夜节律调节血流对基于纳米颗粒的靶向药物递送在虚拟体内动脉几何结构中的影响 |
Goraya, S. A. |
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N/A |
Effect of Circadian Rhythm Modulated Blood Flow on Nanoparticle based Targeted Drug Delivery in Virtual In Vivo Arterial Geometries |
| 一个转录因子五重奏调控水稻鞘鞘表达 |
Hua, L. |
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N/A |
A transcription factor quintet orchestrating bundle sheath expression in rice |
| 人类下丘中的快速且刺激特异性的异常检测 |
Wetekam, J. |
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N/A |
Rapid and Stimulus-Specific Deviance Detection in the Human Inferior Colliculus |
| regulaTER：一个用于研究转座元件调控作用的R语言库。 |
Eskier, D. |
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N/A |
regulaTER: An R Library to Study the Regulatory Roles of Transposable Elements. |
| 一种能够穿越血脑屏障的肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了与抗惊厥、神经保护和抗炎特性相关的药理性体温过低。 |
Ferhat, L. |
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N/A |
A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice |
| 内在无序蛋白质凝聚体中动力学的异质性减缓 |
Mukherjee, S. |
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N/A |
Heterogeneous Slowdown of Dynamics in the Condensate of an Intrinsically Disordered Protein |
| BioLP-bench：评估大型语言模型对生物实验室协议的理解能力 |
Ivanov, I. |
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N/A |
BioLP-bench: Measuring understanding of biological lab protocols by large language models |
| 在烟草中异源生产环肽素B：揭示植物特异性插入结构域在蛋白质功能和亚细胞定位中的作用 |
Muthusamy, S. |
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N/A |
Heterologous Production of Cyprosin B in Nicotiana benthamiana: Unveiling the Role of the Plant-Specific Insert Domain in Protein Function and Subcellular Localization |
| 遗传抑制相互作用在不同遗传背景下高度保守 |
Paltenghi, C. |
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N/A |
Genetic suppression interactions are highly conserved across genetic backgrounds |
| 柱状胆碱能神经传递到果蝇T5细胞 |
Samara, E. |
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N/A |
Columnar cholinergic neurotransmission onto T5 cells of Drosophila |
| 两种形态迥异的蜂媒授粉茄科植物花朵中花粉的命运 |
Vasquez-Castro, C. A. |
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N/A |
The fate of pollen in two morphologically contrasting buzz-pollinated Solanum flowers |
| 磷酸酶非依赖性抑制黏膜炎症和疾病进展的沙门氏菌SopB |
Diab, N. |
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N/A |
Phosphatase-independent suppression of mucosal inflammation and disease progression by Salmonella SopB |
| 内皮CD45在调节动脉粥样硬化中的内皮间质转化的新作用 |
Peng, Q. |
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N/A |
Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis |
| 海马体中奖励的预测编码 |
Yaghoubi, M. H. |
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N/A |
Predictive Coding of Reward in the Hippocampus |
| 丝虫精子发生过程中重组、X染色体失活及着丝粒蛋白的动态变化 |
Toubiana, W. |
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N/A |
Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis |
| 增加留尼汪岛节肢动物名录 |
Nibouche, S. |
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N/A |
Additions to the list of arthropods of Reunion Island |
| 质子结合的变构调节赋予囊泡谷氨酸转运蛋白氯离子活化和谷氨酸选择性 |
Borghans, B. |
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N/A |
Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters |
| 转录因子Traffic jam在果蝇卵巢中调控体细胞piRNA通路 |
Alizada, A. |
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N/A |
The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries |
| 急性饮食甲硫氨酸限制突显了新皮质发育对代谢变化的敏感性 |
Saha, S. |
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N/A |
Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations |
| 裂变酵母SUMO靶向泛素连接酶Slx8在功能上与核周的成簇着丝粒和沉默的交配型区域相关联。 |
Chakraborty, S. |
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N/A |
The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery |
| 在磷酸盐限制条件下，革兰氏阴性ESKAPE病原体通过替代脂质合成途径促进抗生素耐受性。 |
Olea-Ozuna, R. J. |
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N/A |
Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens |
| IgSF蛋白DIP-α和Dpr10的关键亲和窗口对于适当的运动神经元树突化是必需的。 |
Lopez, D. |
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N/A |
A critical affinity window for IgSF proteins DIP-alpha and Dpr10 is required for proper motor neuron arborization |
| 河流丽鱼（辐鳍鱼纲，慈鲷科）的完整线粒体基因组，重点关注盲丽鱼L. lethops |
Jimenez, S. |
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N/A |
Complete mitochondrial genomes of riverine Lamprologus (Actinopterygii, Cichlidae) with an emphasis on the blind cichlid L. lethops |
| 适应性唤醒调节：通过儿茶酚胺增强唤醒来药理学地改变耶克斯-多德森曲线的峰值 |
Beerendonk, L. |
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N/A |
Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal |
| ABHD11介导的去甘露糖化作用调控TCA循环和T细胞代谢 |
Grice, G. L. |
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N/A |
ABHD11 mediated deglutarylation regulates the TCA cycle and T cell metabolism |
| 母体致肥胖饮食在中孕期会破坏子宫内膜的免疫和血管稳态，但不会影响螺旋动脉的重塑。 |
Bellissimo, C. J. |
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N/A |
Maternal obesogenic diet disrupts mid-gestation decidual immune and vascular homeostasis without impairing spiral artery remodelling |
| 遗传性铜缺乏和儿童神经退行性变模型中的适应性蛋白质合成 |
Lane, A. R. |
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N/A |
Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration |
| 蛋白质稳态和代谢功能障碍在特定的一组储存诱导的衰老红细胞中，这些红细胞被靶向清除 |
Peltier, S. |
PDF |
N/A |
Proteostasis and metabolic dysfunction in a distinct subset of storage-induced senescent erythrocytes targeted for clearance |
| 人类动脉粥样硬化斑块的综合单细胞图谱 |
Traeuble, K. |
PDF |
N/A |
Integrated single-cell atlas of human atherosclerotic plaques |
| 甲型流感病毒利用宿主细胞中膜细胞骨架肌动蛋白丝的运动性进行其基因组的包装。 |
Wang, I.-H. |
PDF |
N/A |
Influenza A virus exploits the motility of membrane cytoskeletal actomyosin filaments for its genome packaging in the host cell |
| 胞内体重组疗法：一种从囊性纤维化中进行的生物学拯救 |
Cho, W. J. |
PDF |
N/A |
Porosome reconstitution therapy: A biologic rescue from cystic fibrosis |
| 自闭症和智力障碍相关MYT1L基因突变影响人类皮层中间神经元的分化、成熟和生理功能 |
Prakasam, R. |
PDF |
N/A |
Autism and Intellectual Disability-Associated MYT1L Mutation Alters Human Cortical Interneuron Differentiation, Maturation, and Physiology |
| 吉尔伽美什，果蝇酪蛋白激酶1g，对于肌球蛋白依赖的连接增强和上皮折叠是必需的。 |
Gu, L. |
PDF |
N/A |
gilgamesh, Drosophila casein kinase 1g, is required for myosin-dependent junction strengthening and epithelial folding |
| 心脏成纤维细胞通过胶原蛋白信号通路调节心肌和冠状血管的发育。 |
Deng, Y. |
PDF |
N/A |
Cardiac Fibroblasts regulate myocardium and coronary vasculature development via the collagen signaling pathway |
| 大规模小鼠突变分析鉴定出影响脊椎发育的新基因。 |
Ibarra-Soria, X. |
PDF |
N/A |
Large-scale mouse mutagenesis identifies novel genes affecting vertebral development. |
| 卵母细胞锌转运蛋白Slc39a10/Zip10是小鼠受精过程中锌火花调节器。 |
Kageyama, A. |
PDF |
N/A |
The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice. |
| 弓形虫感染会误导胎盘滋养层细胞谱系的分化 |
Cabo, L. F. |
PDF |
N/A |
Toxoplasma gondii infection misdirects placental trophoblast lineage specification |
| 长期活体成像、细胞鉴定及再生甲壳动物腿中的细胞追踪 |
Cevrim, C. |
PDF |
N/A |
Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs |
| 电泳相关离子迁移技术在毛细管电泳质谱单细胞蛋白质组学中的应用 |
Shen, B. |
PDF |
N/A |
Electrophoresis-Correlative Ion Mobility Deepens Single-cell Proteomics in Capillary Electrophoresis Mass Spectrometry |
| Notch活性的基本和双重作用对自然转分化事件的影响 |
Daniele, T. |
PDF |
N/A |
Essential and dual effects of Notch activity on a natural transdifferentiation event |
| 深度学习在荧光全内反射显微镜中动态胞吐事件的检测 |
Lachuer, H. |
PDF |
N/A |
Deep learning detection of dynamic exocytosis events in fluorescence TIRF microscopy |
| 硫胺素预处理控制马铃薯早疫病：其有效性及分子机制的研究 |
Berrian, T. W. |
PDF |
N/A |
Thiamin priming to control early blight in potato: investigation of its effectiveness and molecular mechanisms |
| 细胞松弛素B对肌动蛋白结合蛋白功能的急性干扰 |
Lambert, C. |
PDF |
N/A |
Differential interference with actin-binding protein function by acute Cytochalasin B |
| 蜕膜自然杀伤细胞促进绒毛外滋养层发育途径：来自滋养层类器官共培养的证据 |
Zych, M. |
PDF |
N/A |
Decidual natural killer cells promote extravillous trophoblast developmental pathways: evidence from trophoblast organoid co-cultures |
| 秀丽隐杆线虫染色体内重组率的菌株间变异 |
Matharage, D. U. |
PDF |
N/A |
Inter-strain variation in intra-chromosomal rates of recombination in Caenorhabditis elegans |
| 果蝇饮食限制介导的寿命结果中的随机性 |
Mosley, O. L. |
PDF |
N/A |
Stochasticity in dietary restriction-mediated lifespan outcomes in Drosophila |
| ATG9小泡是一种细胞内纳米小泡的亚型。 |
Fesenko, M. |
PDF |
N/A |
ATG9 vesicles are a subtype of intracellular nanovesicle |
| 母亲孕期抑郁症状与新生儿胼胝体完整性之间的关联及其与孕期头发皮质醇浓度的关系 |
Mariani Wigley, I. L. C. |
PDF |
N/A |
Association between maternal depressive symptoms and hair cortisol concentration during pregnancy with corpus callosum integrity in newborns |
| 利用三倍频显微镜对生理上保存完好的人脑组织中的髓鞘病理进行动态成像 |
Meijns, N. |
PDF |
N/A |
Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy |
| 在环境与遗传空间中的杂种优势 |
Sandstedt, G. D. |
PDF |
N/A |
Heterosis across an environmental and genetic space |
| 突触小泡停靠与融合孔调节：神经钙传感器Synaptotagmin-1的作用 |
Tsemperouli, M. |
PDF |
N/A |
Vesicle docking and fusion pore modulation by the neuronal calcium sensor Synaptotagmin-1 |
| 水滴的燃烧玻璃效应在拟南芥叶片叶绿体基质中触发了内质网衍生的钙响应 |
Kuang, D. |
PDF |
N/A |
Burning glass effect of water droplets triggers an ER-derived calcium response in the chloroplast stroma of Arabidopsis thaliana leaves |
| 通过时间和波长分辨的氧化还原生物传感器以及叶绿素荧光量化电子传递相关的氧化信号 |
Hipsch, M. |
PDF |
N/A |
Quantification of electron transport-related oxidative signals by time and wavelength-resolved redox biosensors and chlorophyll fluorescence |
| 探索玉米地方品种根系表型的产量稳定性和适应性景观的计算机模拟 |
Lopez-Valdivia, I. |
PDF |
N/A |
Exploring yield stability and the fitness landscape of maize landrace root phenotypes in silico |
| 不同的输入特异性机制使得突触前稳态可塑性成为可能 |
Chien, C. |
PDF |
N/A |
Distinct input-specific mechanisms enable presynaptic homeostatic plasticity |
| ERK2二聚体在突触可塑性和记忆中的作用 |
Ojea Ramos, S. |
PDF |
N/A |
Role of ERK2 dimerization in synaptic plasticity and memory |
| 辅助调节通过NLRP3/IL-1途径塑造适应性免疫反应，并促进训练性免疫耐受。 |
Boccia, T. |
PDF |
N/A |
Adjuvant conditioning shapes the adaptive immune response and promotes trained immunotolerance via NLRP3/IL-1 |
| 雷帕霉素改变了雌性果蝇对氨基酸和糖的摄食偏好 |
Yu, G. |
PDF |
N/A |
Rapamycin alters the feeding preference for amino acids and sugar in female Drosophila |
| 突触间可塑性变异性的平衡，以生成输入端广泛的递质释放恒定性。 |
Aghi, K. |
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Synapse-to-synapse plasticity variability balanced to generate input-wide constancy of transmitter release |
| 小鼠中自发再生的皮质脊髓神经元 |
Fait, B. W. |
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N/A |
Spontaneously regenerative corticospinal neurons in mice |
| 辅助嗅球中的突触抑制调节信息素定位学习和记忆 |
Marathe, S. D. |
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Synaptic inhibition in the accessory olfactory bulb regulates pheromone location learning and memory |
| 利用突触囊泡释放和再循环机制进行分子递送至神经元 |
Yee, K. K. |
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N/A |
Harnessing Synaptic Vesicle Release and Recycling Mechanism for Molecule Delivery to Neurons |
| 极端疼痛毒液的多重作用机制 |
Borjon, L. J. |
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Multiple mechanisms of action of an extremely painful venom |
| 神经肽能对胆碱能传递的调控丧失会引发肌肉细胞中由CaV1介导的稳态补偿 |
Shao, J. |
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Loss of neuropeptidergic regulation of cholinergic transmission induces CaV1-mediated homeostatic compensation in muscle cells |
| 整合双目视觉和运动状态以促进猎物追捕 |
Tian, G. |
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Integration of binocular vision and motor state to promote prey pursuit |
| m6A RNA修饰在转录组学层面调节了衰老和突触核蛋白病小鼠模型中的突触功能。 |
Chopra, A. |
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The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy |
| 使用冷冻电镜和人工智能进行蛋白质鉴定指导了改进的样品纯化 |
Carr, K. D. |
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Protein identification using cryo-EM and artificial intelligence guides improved sample purification |
| 外纹状皮质中误报的神经动力学基础 |
Sahoo, B. |
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Neural Dynamics Underlying False Alarms in Extrastriate Cortex |
| Context-Seq: 基于CRISPR-Cas9靶向纳米孔测序的抗菌药物耐药性传播动力学研究 |
Fuhrmeister, E. R. |
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Context-Seq: CRISPR-Cas9 Targeted Nanopore Sequencing for Transmission Dynamics of Antimicrobial Resistance |
| 解锁隐藏噬菌体多样性，以完成BASEL收藏，系统探索噬菌体-宿主相互作用 |
Humolli, D. |
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Unlocking hidden phage diversity to complete the BASEL collection for systematic exploration of phage-host interactions |
| 一种古菌的CBASS系统能在不杀死宿主细胞的情况下消除病毒 |
Choudhary, D. K. |
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An archaeal CBASS system eliminates viruses without killing the host cells |
| 西高加索蝙蝠病毒在意外宿主体内的免疫学发现 |
Castellan, M. |
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N/A |
Immunological findings of West Caucasian bat virus in an accidental host |
| 评估TRX和DUF148抗原用于检测犬类潜伏期麦地那龙线虫（Dracunculus medinensis）感染的性能 |
Hakimi, H. |
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Assessing the performance of TRX and DUF148 antigens for detection of prepatent Guinea worm (Dracunculus medinensis) infection in dogs |
| 计算研究表明揭示了条形柄锈菌小麦专化型效应蛋白的结构特征和新家族 |
Asghar, R. |
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Computational studies reveal structural characterization and novel families of Puccinia striiformis f. sp. tritici effectors |
| 通过凝集素微阵列对乳酸乳球菌乳酸亚种突变体进行糖型分析 |
Suzuki, E. |
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Glyco-phenotyping of mutants of Lacticaseibacillus paracasei by lectin microarray |
| 对单个噬菌体和噬菌体混合物的宏基因组分析显示，存在温和噬菌体和细菌DNA的污染情况。 |
Peng, X. |
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Metagenomic analyses of single phages and phage cocktails show instances of contamination with temperate phages and bacterial DNA |
| 不同寡聚态流感病毒核蛋白的多克隆和单克隆抗体分析 |
Myers, M. L. |
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Analysis of polyclonal and monoclonal antibody to the influenza virus nucleoprotein in different oligomeric states |
| ves1α基因表达是巴贝斯虫感染的红细胞与内皮细胞粘附的主要决定因素。 |
Hakimi, H. |
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ves1α genes expression is the major determinant of Babesia bovis-infected erythrocytes cytoadhesion to endothelial cells |
| 一种基于黄素的新型革兰氏阳性菌Microbacterium deferre sp. nov.菌株A1-JK中的胞外电子传递策略，该菌株从电缆细菌富集物中分离得到。 |
Lustermans, J. J. M. |
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A flavin-based extracellular electron transfer strategy in a novel gram-positive microbe Microbacterium deferre sp. nov. strain A1-JK, isolated from cable bacteria enrichments |
| 电磁波能破坏SARS-CoV-2的刺突蛋白，并降低SARS-CoV-2病毒样颗粒（SC2-VLP）的感染性。 |
Granatir, S. |
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Electromagnetic waves destabilize the SARS-CoV-2 Spike protein and reduce SARS-CoV-2 Virus-Like Particle (SC2-VLP) infectivity |
| 通过筛选组蛋白突变体，我们发现组蛋白H3的N端尾部内存在一个区域，该区域调控Cyc8在活性FLO1位点上独立于Tup1的抑制作用。 |
Singh, R. |
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Screening of histone mutants reveals a domain within the N-terminal tail of histone H3 that regulates the Tup1-independent repressive role of Cyc8 at the active FLO1 |
| 通过调节炎症和促消退脂质介质的平衡，改善体积性肌肉损失损伤的功能性肌肉再生 |
Turner, T. C. |
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Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid Mediators |
| NucBalancer：优化样本混合用于测序的条码序列选择流程 |
Gupta, S. |
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NucBalancer: Streamlining Barcode Sequence Selection for Optimal Sample Pooling for Sequencing |
| 应激介导的生长决定大肠杆菌分裂位点的形态发生 |
Pelech, P. |
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Stress-mediated growth determines E. coli division site morphogenesis |
| 凝血因子XII参与了肾素激活、心力衰竭进展及死亡率的相关过程。 |
Gladysheva, I. P. |
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Coagulation factor XII contributes to renin activation, heart failure progression, and mortality |
| 一种KCa 2.2/2.3开放剂可逆转ET-1诱导的高血压小鼠NLRP3的激活 |
Sobrano Fais, R. |
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A KCa 2.2/2.3 opener reverses ET-1 induced NLRP3 activation in hypertensive mice |
| 细菌的储层计算 |
Faulon, J.-L. |
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Reservoir Computing with Bacteria |
| 血清素能致幻剂DOI会损害听觉皮层的异常检测能力。 |
Horrocks, M. |
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The serotonergic psychedelic DOI impairs deviance detection in the auditory cortex |
| 不依赖宿主蛋白酶的寨卡病毒感染性成熟颗粒的生物发生 |
Dowd, K. A. |
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pr-independent biogenesis of infectious mature Zika virus particles |
| 综合宿主体内感染动力学揭示了被忽视的媒介物种白纹伊蚊（Aedes scutellaris）具有较高的虫媒病毒传播潜力 |
Samung, Y. |
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Comprehensive intra-host infection kinetics reveals high arbo-flavivirus transmission potential by neglected vector species, Aedes scutellaris |
| 双天线N-聚糖作为MARTX毒素在弧菌致病性中的受体 |
Chen, J. |
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Biantennary N-glycans As Receptors for MARTX Toxins in Vibrio Pathogenesis |
| 卡尔斯巴德洞窟国家公园的洞穴池中存在着多样化的噬菌体群落和新型病毒序列。 |
Ulbrich, J. |
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Cave pools in Carlsbad Caverns National Park contain diverse bacteriophage communities and novel viral sequences |
| 无机多磷酸盐与严紧反应共同调控大肠杆菌的细胞分裂和细胞形态 |
Hamm, C. W. |
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Inorganic polyphosphate and the stringent response coordinately control cell division and cell morphology in Escherichia coli |
| 衣原体效应蛋白Tarp的N端与宿主Hippo通路相互作用。 |
Aranjuez, G. F. |
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The N-terminus of the Chlamydia trachomatis effector Tarp engages the host Hippo pathway |
| MtvS调节弗朗西氏菌V-A型CRISPR-Cas系统 |
Brodmann, M. |
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MtvS Regulates the Francisella Type V-A CRISPR-Cas System |
| Hox转录因子Ultrabithorax的协同DNA和RNA结合能力协调剪接并塑造体内同源异型功能 |
Blanco, C. |
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Synergistic DNA and RNA binding of the Hox transcription factor Ultrabithorax coordinates splicing and shapes in vivo homeotic functions |
| Cas9核酸酶的策略性靶向扩展了串联基因阵列 |
Takesue, H. |
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Strategic targeting of Cas9 nickase expands tandem gene arrays |
| 营养缺乏会激活与炎症性肠病风险相关的细胞外基质重塑基因增强子，这一过程在成纤维细胞中尤为显著。 |
Secchia, S. |
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Nutrient starvation activates ECM remodeling gene enhancers associated with inflammatory bowel disease risk in fibroblasts |
| 由III组代谢型谷氨酸受体介导的抑制作用调节着缰核的活动及防御行为 |
Ostenrath, A. M. |
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Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors |
| 稳定选择使复杂性状的尾部富集了具有较大效应的罕见等位基因。 |
Ori, A. P. |
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Stabilising selection enriches the tails of complex traits with rare alleles of large effect |
| 老年人大脑中微小RNA的基因调控及其对神经精神疾病的影响 |
Vattathil, S. M. |
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Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions |
| 利用批量和靶向单细胞激活技术对基因组调控景观进行敏感解剖 |
Vucicevic, D. |
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N/A |
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation |
| GAF结构域介导肌醇焦磷酸底物在PPIP5K磷酸酶中的通道作用 |
Raia, P. |
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A GAF domain mediates inositol pyrophosphate substrate channeling in PPIP5K phosphatases |
| 二聚体SMC复合物进行的环挤压对称性依赖于DNA张力 |
Pradhan, B. |
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Symmetry of loop extrusion by dimeric SMC complexes is DNA-tension-dependent |
| ARF降解定义了生长素反应中一个高度保守的步骤。 |
de Roij, M. |
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ARF degradation defines a deeply conserved step in auxin response |
| 单锥光感受器通过注视转移来体验全局图像统计信息。 |
Morimoto, T. |
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Single cone photoreceptors experience global image statistics through gaze shifts |
| α5-GABAA受体的正向变构调节可预防PS19小鼠模型中神经元萎缩和认知功能下降，且独立于tau缠结的积累。 |
Dharavath, R. N. |
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Positive Allosteric Modulation of the α5-GABAA receptors prevents neuronal atrophy and cognitive decline independently of tau tangle accumulation in the PS19 mouse model |
| 在额下皮质中，解剖学上不同的区域受到任务和阅读技能的调节。 |
Stone, H. L. |
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Anatomically distinct regions in the inferior frontal cortex are modulated by task and reading skill |
| 肾上腺素能C1神经元通过投射到中脑导水管周围灰质（PAG）来增强焦虑。 |
Fernandez-Pena, C. |
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Adrenergic C1 neurons enhance anxiety via projections to PAG |
| 辅助剂对疫苗诱导的体液免疫反应和保护作用的影响：在鼻腔和生殖道定植病原性奈瑟菌的临床前模型中 |
Islam, E. A. |
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Adjuvant-dependent impacts on vaccine-induced humoral responses and protection in preclinical models of nasal and genital colonization by pathogenic Neisseria |
| 体外构建巨噬细胞极化模型：以Raw 264.7巨噬细胞系为例 |
Yee, K. K. |
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An in vitro modelling of resolving macrophage with Raw 264.7 macrophage cell line |
| 小鼠心脏中伴侣复合体的年龄相关变化 |
Bhat, P. D. |
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Age-dependent Changes in a Chaperone Complex in the Mouse Heart |
| 全球蛋白质组学揭示了电离辐射诱导的亚细胞特异性抗铁死亡反应 |
Christopher, J. A. |
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N/A |
Global proteomics indicates subcellular-specific anti-ferroptotic responses to ionizing radiation |
| 有丝分裂驱动蛋白-5是轴突生长的动态刹车 |
Lu, W. |
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N/A |
'Mitotic' kinesin-5 is a dynamic brake for axonal growth |
| 钙网蛋白在蝴蝶翅膀鳞片细胞内的角质层沉积和横梁形成过程中是必需的。 |
Hong, R. |
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N/A |
Calreticulin is required for cuticle deposition and trabeculae formation inside butterfly wing scale cells |
| PSMA特异性CAR改造的巨噬细胞用于前列腺癌治疗 |
Xu, Y. |
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N/A |
PSMA-specific CAR-engineered macrophages for therapy of prostate cancer |
| 肌球蛋白簇动力学决定上皮伤口环收缩 |
Bhat, A. |
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N/A |
Myosin cluster dynamics determines epithelial wound ring constriction |
| 无参数清晰图像反卷积（CLID）技术用于单帧活细胞超分辨率成像 |
Xue, F. |
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Parameter-free clear image deconvolution (CLID) technique for single-frame live-cell super-resolution imaging |
| 痛风药物抑制尿酸转运蛋白URAT1的分子基础 |
Suo, Y. |
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Molecular basis of the urate transporter URAT1 inhibition by gout drugs |