| 复杂非整倍体触发自噬和p53介导的凋亡，并损害人类植入前胚胎中的第二次谱系分离 |
Regin, M. |
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N/A |
Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos |
| GEARBOCS：一种用于星形胶质细胞体内基因编辑的腺相关病毒工具 |
Sivadasan Bindu, D. |
PDF |
N/A |
GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes |
| 肉食性有袋动物颅面发育过程中的基因调控动态 |
Cook, L. E. |
PDF |
N/A |
Gene regulatory dynamics during craniofacial development in a carnivorous marsupial |
| 从自运动信号中抄近路：量化开放迷宫中的轨迹和主动感知 |
Xu, J. |
PDF |
N/A |
Shortcutting from self-motion signals: quantifying trajectories and active sensing in an open maze |
| 稳态突触归一化优化了神经群体编码网络模型中的学习 |
Mayzel, J. |
PDF |
N/A |
Homeostatic synaptic normalization optimizes learning in network models of neural population codes |
| 睾酮通过膜蛋白GPRC6A在斑马鱼胚胎中引起心脏水肿 |
Zadmajid, V. |
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N/A |
Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos |
| G蛋白偶联受体TBXA2R激活ERM蛋白以调控三阴性乳腺癌细胞的迁移和侵袭。 |
Leguay, K. |
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N/A |
The G protein-coupled receptor TBXA2R activates ERMs to control cell motility and invasion of triple-negative breast cancer cells. |
| CAMP：一个模块化的宏基因组分析系统，用于综合的多步骤数据探索 |
Mak, L. |
PDF |
N/A |
CAMP: A modular metagenomics analysis system for integrated multi-step data exploration |
| 前额叶皮层第五层锥体神经元的特定亚型中存在特定异构体的烟碱样反应 |
Patel, A. V. |
PDF |
N/A |
Isoform-specific nicotinic responses are present in distinct subtypes of prefrontal layer V pyramidal neurons |
| 一种毫秒级粗粒度模拟方法用于解析大麻素在甘氨酸受体α1上的别构结合 |
Bartocci, A. |
PDF |
N/A |
A millisecond coarse-grained simulation approach to decipher allosteric cannabinoid binding at the glycine receptor α1 |
| 大型生物银行队列中随访数据的分析：方法学综述 |
Kolde, A. |
PDF |
N/A |
Analysis of follow-up data in large biobank cohorts: a review of methodology |
| DNA修复背景与目标序列的相互作用可预测地偏向于Cas9生成的突变。 |
Pallaseni, A. |
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N/A |
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations |
| 溶酶体的外周定位支持黑色素瘤的侵袭性 |
Jerabkova-Roda, K. |
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N/A |
Peripheral positioning of lysosomes supports melanoma aggressiveness |
| Fragle：利用深度学习对片段组学特征进行泛癌种循环肿瘤DNA定量 |
Jacobsen Skanderup, A. |
PDF |
N/A |
Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles |
| 下一代杀虫剂氟吡呋喃酮与真菌病原体的协同效应 |
Schlaeppi, D. |
PDF |
N/A |
Synergistic effects of the next generation insecticide flupyradifurone with a fungalpathogen |
| VACmap：一种用于解析复杂基因组重排的精确长读对齐工具 |
Ding, H. |
PDF |
N/A |
VACmap: An Accurate Long-Read Aligner for Unraveling Complex Genomic Rearrangements |
| 时间和奖励的竞争性整合解释了价值敏感的觅食决策以及前额叶皮层的渐进动力学 |
Bukwich, M. |
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N/A |
Competitive integration of time and reward explains value-sensitive foraging decisions and frontal cortex ramping dynamics |
| 亲吻素纤维及其受体分布分析表明，其在中枢感觉处理和行为状态控制中可能发挥作用。 |
Zhang, L. |
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N/A |
Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control |
| 揭示区间通讯信号轴：线粒体至内质网应激反应（MERSR）及其对蛋白质稳态的影响 |
Li, J. J. |
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N/A |
Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis |
| 健康老龄化中流体智力功能补偿的神经证据 |
Knights, E. |
PDF |
N/A |
Neural Evidence of Functional Compensation for Fluid Intelligence in Healthy Ageing |
| 早期植入前酒精暴露后小鼠胎盘中性别特异性DNA甲基化和基因表达变化 |
Legault, L.-M. |
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N/A |
Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure |
| 在空间解析的组学数据中，表征细胞类型在不同尺度上的空间关系 |
dos Santos Peixoto, R. |
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N/A |
Characterizing cell-type spatial relationships across length scales in spatially resolved omics data |
| 芳香烃受体限制背根神经节神经元在损伤后的轴突再生 |
Halawani, D. |
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N/A |
Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury |
| 视前区控制遗传性癫痫小鼠模型中与睡眠相关的癫痫发作起始 |
Potesta, C. V. |
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N/A |
Preoptic area controls sleep-related seizure onset in a genetic epilepsy mouse model |
| 泛素特异性蛋白酶USP8的时空招募指导了内体成熟过程 |
Miao, Y. |
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N/A |
Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation |
| TimberTracer：一个综合框架，用于评估森林管理和采伐木材产品替代对碳固存的影响。 |
Boukhris, I. |
PDF |
N/A |
TimberTracer: A Comprehensive Framework for the Evaluation of Carbon Sequestration by Forest Management and Substitution of Harvested Wood Products. |
| 微管干扰后iPSC衍生模型系统中神经突延伸和核运动的测量 |
Sebastien, M. |
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N/A |
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation |
| 尼帕病毒融合蛋白的纳米级结构揭示了新的膜融合机制。 |
Wang, Q. |
PDF |
N/A |
The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms. |
| MolSnapper：基于结构的药物设计中的条件扩散 |
Ziv, Y. |
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N/A |
MolSnapper: Conditioning Diffusion for Structure Based Drug Design |
| 栖息地破碎化介导了鸟类长期气候驱动的热嗜性机制 |
Liu, J. |
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N/A |
Habitat fragmentation mediates the mechanisms underlying long-term climate-driven thermophilization in birds |
| 催化功能不同的IDH1突变体在肿瘤模型中调节表型严重性 |
Adam, M. A. A. |
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N/A |
Catalytically distinct IDH1 mutants tune phenotype severity in tumor models |
| 沙眼衣原体的T3SS结构基因和效应基因在不同的表型细胞形态中表达。 |
Grieshaber, N. |
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N/A |
The T3SS structural and effector genes of Chlamydia trachomatis are expressed in distinct phenotypic cell forms. |
| 长精子优先权与果蝇（Drosophila melanogaster）中其他隐秘的雌性选择 |
Peckenpaugh, B. |
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N/A |
Long-sperm precedence and other cryptic female choices in Drosophila melanogaster |
| SLC35G1：一种高度氯离子敏感的转运蛋白，负责肠上皮细胞基底侧膜的柠檬酸盐吸收转运。 |
Mimura, Y. |
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N/A |
SLC35G1: A highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption |
| 有丝分裂期间PI(3,5)P2不对称性对于不对称液泡遗传至关重要 |
Huda, M. |
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N/A |
PI(3,5)P2 asymmetry during mitosis is essential for asymmetric vacuolar inheritance |
| 青少年时期大脑形态与认知功能之间的关联：基于9至15岁全面大规模分析的见解 |
Yan, J. |
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N/A |
Association between Brain Morphometry and Cognitive Function during Adolescence: Insights from a Comprehensive Large-Scale Analysis from 9 to 15 Years Old |
| MIROSLAV：一个完整的开源硬件和软件工具包，用于啮齿动物高吞吐量昼夜节律活动测量和分析 |
Virag, D. |
PDF |
N/A |
MIROSLAV: A complete open-source hardware and software toolkit for high-throughput circadian activity measurement and analysis in rodents |
| B细胞受体依赖性增强登革病毒感染 |
Gebo, C. |
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N/A |
B cell receptor dependent enhancement of dengue virus infection |
| TRPML1门控通过别构突变和脂质的调节 |
Gan, N. |
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N/A |
TRPML1 gating modulation by allosteric mutations and lipids |
| 刺胞动物XIAP激活半胱天冬酶介导的细胞死亡 |
Chen, Y. |
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N/A |
Cnidaria XIAP activates caspase-mediated cell death |
| 直接从梨状皮层到听觉皮层的投射塑造了听觉与嗅觉的整合 |
Vogler, N. W. |
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N/A |
Direct piriform-to-auditory cortical projections shape auditory-olfactory integration |
| 理解压力变性的物理决定因素：利用高压核磁共振技术探究Yfh1在不同温度下的展开途径 |
Roumestand, C. |
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N/A |
Understanding the physical determinants of pressure denaturation: Exploring the unfolding pathways of Yfh1 at different temperatures with High-Pressure NMR |
| CRISPR RNA结合驱动结构有序化，为Cas7-11的靶标切割做好准备 |
Lin, C. P. |
PDF |
N/A |
CRISPR RNA binding drives structural ordering that primes Cas7-11 for target cleavage |
| 不同表型水稻干旱和盐胁迫公共RNA测序数据的Meta分析 |
Shintani, M. |
PDF |
N/A |
Meta-analysis of public RNA-sequencing data of drought and salt stresses in different phenotypes of Oryza sativa |
| 肾癌细胞通过吞噬作用和水平基因转移获取免疫表面蛋白 |
Marcarian, H. Q. |
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N/A |
Renal cancer cells acquire immune surface protein through trogocytosis and horizontal gene transfer |
| 无序蛋白质及其凝聚物的酶促磷酸化分子模拟 |
Zippo, E. |
PDF |
N/A |
Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates |
| 单胺氧化酶C（MAO C）的进化与功能分析：MAO基因家族的新成员 |
Merello, G. |
PDF |
N/A |
Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family |
| 原子级自由能景观揭示了蜜二糖转运蛋白的协同共转运机制 |
Liang, R. |
PDF |
N/A |
Atomic-Level Free Energy Landscape Reveals Cooperative Symport Mechanism of Melibiose Transporter |
| 电鳗（Electrophorus）电器官中由腹侧向背侧的电细胞发育。 |
Senarat, S. |
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N/A |
Ventral-to-dorsal electrocyte development in electric organs of electric eel (Electrophorus). |
| 评估用于跨癌症适应症比较蛋白质表达的计算方法 |
Wang, J. |
PDF |
N/A |
Evaluating computational approaches for comparison of protein expression across cancer indications |
| AlphaFold2 SLiM筛选自噬中LC3-LIR相互作用 |
Stuke, J. F. M. |
PDF |
N/A |
AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy |
| 小鼠心脏中伴侣蛋白复合物的年龄相关变化 |
Bhat, P. D. |
PDF |
N/A |
Age-dependent Changes in a Chaperone Complex in the Mouse Heart |
| 白色念珠菌与粪肠球菌之间的跨菌种宿主细胞协同损伤 |
Kapitan, M. |
PDF |
N/A |
Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis |
| CNValidatron，利用计算机视觉实现CNV调用的自动化验证 |
Montalbano, S. |
PDF |
N/A |
CNValidatron, automated validation of CNV calls using computer vision |
| 使用结构方程模型预测噪声中语音识别能力：基于静态与动态听觉图形-背景分析 |
Guo, X. |
PDF |
N/A |
Predicting speech-in-noise ability with static and dynamic auditory figure-ground analysis using structural equation modelling |
| 在海马体的循环网络模型中，条形码活动能够实现高效的记忆绑定。 |
Fang, C. |
PDF |
N/A |
Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding |
| 番茄和茄子幼苗茎部软化和半透明形态学特征，由Ralstonia pseudosolanacearum F1C1感染引起 |
Bhuyan, S. |
PDF |
N/A |
Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1 |
| Colora：一个用于完成染色体规模从头基因组组装的Snakemake工作流程 |
Obinu, L. |
PDF |
N/A |
Colora: A Snakemake Workflow for Complete Chromosome-scale De Novo Genome Assembly |
| 骨附着土壤作为目标和环境DNA及蛋白质的来源 |
de Dios Martinez, T. |
PDF |
N/A |
Bone adhered soil as a source of target and environmental DNA and proteins |
| 解剖变异及其他血管因素对筛板低氧的影响 |
Lu, Y. |
PDF |
N/A |
Impact of anatomic variability and other vascular factors on lamina cribrosa hypoxia |
| 使用单细胞RNA测序数据的拷贝数变异推断方法基准研究 |
Chen, X. |
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N/A |
A benchmarking study of copy number variation inference methods using single-cell RNA-sequencing data |
| spaDesign：一种改进基于测序的空间转录组学实验设计的统计框架 |
Xie, J. |
PDF |
N/A |
spaDesign: A Statistical Framework to Improve the Design of Sequencing-based Spatial Transcriptomics Experiments |
| Convpaint - 使用预训练神经网络进行交互式像素分类的通用框架 |
Hinderling, L. |
PDF |
N/A |
Convpaint - Universal framework for interactive pixel classification using pretrained neural networks |
| 增强NADPH以恢复G6PD缺乏的微胶质细胞中的氧化还原稳态和溶酶体功能 |
Mondal, A. |
PDF |
N/A |
Enhancing NADPH to Restore Redox Homeostasis and Lysosomal Function in G6PD-Deficient Microglia |
| 环境介导的相互作用导致微生物中外部化和集体记忆的形成 |
Gajrani, S. |
PDF |
N/A |
Environment-mediated interactions cause an externalized and collective memory in microbes |
| 拟病毒、类Sputnik病毒和转拟病毒之间的寄生和共生相互作用：理论和动力系统方法。 |
ORTEGA ATEHORTUA, E. |
PDF |
N/A |
Parasitic and Commensal interactions among Mimiviruses, Sputnik-like virophages, and Transpovirons: A theoretical and dynamical systems approach. |
| 肌因子FGF21与ALS中增强的生存率相关，并能减轻应激诱导的细胞毒性。 |
Guha, A. |
PDF |
N/A |
The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity |
| 人类视觉皮层在准备期间的双格式注意力模板 |
Chen, Y. |
PDF |
N/A |
Dual-format attentional template during preparation in human visual cortex |
| 人类气味辨别学习中特异性和迁移的对比模式 |
Chang, X. |
PDF |
N/A |
Contrasting patterns of specificity and transfer in human odor discrimination learning |
| 酒精和可卡因滥用对成人海马体神经元和非神经元细胞周转的影响 |
Alkass, K. |
PDF |
N/A |
Effect of Alcohol and Cocaine Abuse on Neuronal and Non-Neuronal Cell Turnover in the Adult Human Hippocampus |
| 缺乏皮质抑素会加重中风后的神经功能损伤，并加剧与衰老相关的神经胶质和血管功能障碍。 |
Castillo Gonzalez, J. |
PDF |
N/A |
Lack of cortistatin worsens neurological outcome and exacerbates aging-related glial and vascular dysfunction in stroke |
| 枝角类物种的共存如何影响它们的肠道微生物群？ |
Houwenhuyse, S. |
PDF |
N/A |
How does co-occurrence of Daphnia species affect their gut microbiome? |
| 在长期石灰性草地实验中，绵羊放牧并未增强土壤碳的持久性。 |
Encarnation, D. |
PDF |
N/A |
No enhancement of soil carbon persistence by sheep grazing in a long-term calcareous grassland experiment |
| 扩展表型影响社会性蜘蛛的集体行为和生存 |
Parthasarathy, B. |
PDF |
N/A |
Extended Phenotype Influences Collective Behaviour and Survival in a Social Spider |
| 比较转录组和变异分析揭示了肥胖型2型糖尿病大鼠模型胰腺胰岛中脂质运载蛋白2基因的常见分布无义突变 |
Yokoi, N. |
PDF |
N/A |
Comparative transcriptome and variant analyses of the pancreatic islets of a rat model of obese type 2 diabetes identifies a frequently distributed nonsense mutation in the lipocalin 2 gene |
| 茄科植物的全基因组和全遗传学揭示了同源基因在作物工程中的偶然性 |
Benoit, M. |
PDF |
N/A |
Solanum pan-genomics and pan-genetics reveal paralogs as contingencies in crop engineering |
| 提出一种以轴突为中心的分析方法，用于研究眼内压引起的机械损伤 |
Bansal, M. |
PDF |
N/A |
Proposing a methodology for axon-centric analysis of IOP-induced mechanical insult |
| 注意力机制和状态空间基因组语言模型中标记化影响的比较 |
Lindsey, L. M. |
PDF |
N/A |
A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models |
| 揭示单细胞Hi-C数据中的多尺度建筑特征：使用scCAFE方法 |
Wang, F. |
PDF |
N/A |
Unveiling multi-scale architectural features in single-cell Hi-C data using scCAFE |
| ProtRNA：一种通过跨模态迁移学习生成的蛋白质衍生RNA语言模型 |
Zhang, R. |
PDF |
N/A |
ProtRNA: A Protein-derived RNA Language Model by Cross-Modality Transfer Learning |
| m6AConquer：一个用于m6A检测技术统一量化与整合的数据资源 |
Zhao, X. |
PDF |
N/A |
m6AConquer: a Data Resource for Unified Quantification and Integration of m6A Detection Techniques |
| 新皮层和海马体的θ振荡追踪视听整合及言语记忆的重播 |
Biau, E. |
PDF |
N/A |
Neocortical and hippocampal theta oscillations track audiovisual integration and replay of speech memories |
| 聚焦超声增强抗体递送用于帕金森病的治疗 |
Kwon, N. |
PDF |
N/A |
Focused ultrasound enhanced antibody delivery for the treatment of Parkinson's Disease |
| 视黄酸介导的稳态可塑性驱动伏隔核核心细胞类型特异性CP-AMPAR积累及可卡因渴求的孵化 |
Hwang, E.-K. |
PDF |
N/A |
Retinoic acid-mediated homeostatic plasticity drives cell type-specific CP-AMPAR accumulation in nucleus accumbens core and incubation of cocaine craving |
| 较低的感知压力水平在自然处理过程中增强了感知和注意皮层的神经同步性。 |
Craig, J. |
PDF |
N/A |
Lower perceived stress enhances neural synchrony in perceptual and attentional cortices during naturalistic processing |
| 在声音新奇性的进化过程中，运动皮层投射的选择性扩展 |
Isko, E. C. |
PDF |
N/A |
Selective expansion of motor cortical projections in the evolution of vocal novelty |
| 操作性酒精自我给药方式通过调节伏隔核中含GluA2的AMPAR表达和突触活性，从而增强药物的强化特性。 |
Faccidomo, S. |
PDF |
N/A |
Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug |
| 认知功能的调节器：小脑通过整合作用修改人类皮层网络动力学 |
Bansal, K. |
PDF |
N/A |
A modulator of cognitive function: Cerebellum modifies human cortical network dynamics via integration |
| 不同的基底神经节决策动力学在冲突和不确定性下 |
Ging-Jehli, N. R. |
PDF |
N/A |
Distinct basal ganglia decision dynamics under conflict and uncertainty |
| 视觉运动学习中的节省与小脑-丘脑-皮质网络内的连接性变化相关，该网络编码运动误差。 |
Struber, L. |
PDF |
N/A |
Savings in visuomotor learning is associated with connectivity changes within a cerebello-thalamo-cortical network encoding movement errors |
| 神经肌肉骨骼建模揭示了感觉运动皮层中适应性学习的肌肉水平神经动态 |
DeWolf, T. |
PDF |
N/A |
Neuro-musculoskeletal modeling reveals muscle-level neural dynamics of adaptive learning in sensorimotor cortex |
| CHCHD2-CHCHD10蛋白复合物受线粒体功能障碍的调节，并改变小鼠大脑中的脂质稳态。 |
Gerlach, J. |
PDF |
N/A |
The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain. |
| 纵向多组学免疫分析揭示了健康成年人中与年龄相关的免疫细胞动态变化 |
Gong, Q. |
PDF |
N/A |
Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults |
| 利用位点频率比区分选择性与非选择性力量 |
Hey, J. |
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N/A |
Isolating selective from non-selective forces using site frequency ratios |
| 基于基因的适应性模型及其对遗传变异的启示 |
Johri, P. |
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N/A |
A gene-based model of fitness and its implications for genetic variation |
| 推动单分子转录组测序的极限，以揭示人类视网膜神经中最大的疾病相关转录本异构体 |
Stemerdink, M. |
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N/A |
Pushing the limits of single molecule transcript sequencing to uncover the largest disease-associated transcript isoforms in the human neural retina |
| 行为证据表明存在两种注意模式 |
Gupta, A. |
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N/A |
Behavioral Evidence for Two Modes of Attention |
| 篮状细胞中的双峰树突处理驱动与记忆相关的不同振荡 |
Tzilivaki, A. |
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N/A |
Bimodal dendritic processing in basket cells drives distinct memory-related oscillations |
| 一种应激诱导的逆行线粒体运输的分子开关 |
Gladkova, C. |
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N/A |
A molecular switch for stress-induced activation of retrograde mitochondrial transport |
| CD11B+CD36+细胞是促进骨形成的巨噬细胞，能够限制与年龄相关的骨质流失。 |
Koroth, J. |
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N/A |
CD11B+CD36+ cells are bone anabolic macrophages that limit age-associated bone loss |
| CD34+基质细胞/端粒细胞在中年斯普拉格-道利大鼠心肌梗死后愈合过程中表现出动态分布模式 |
Schneider, D. T. |
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N/A |
CD34+ Stromal Cell/Telocytes Demonstrate a Dynamic Pattern of Distribution During Healing of Post-Infarcted Myocardium in Middle-Aged Sprague-Dawley Rats |
| 分析细胞中异常折叠状态蛋白质纤维化的生理影响 |
Levin, T. |
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N/A |
Profiling the physiological impact of aberrant folded-state protein filamentation in cells |
| 神经纤维瘤蛋白丢失通过GLUT1激活诱导炎症性巨噬细胞表型转换和视网膜新生血管形成 |
ZAIDI, Y. |
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N/A |
Loss of Neurofibromin Induces Inflammatory Macrophage Phenotypic Switch and Retinal Neovascularization via GLUT1 Activation |
| 细胞应激对SERPINA1 3'UTR中改变的多聚腺苷酸化位点使用影响A1AT蛋白表达 |
Jiamutai, F. |
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N/A |
Altered polyadenylation site usage in SERPINA1 3'UTR in response to cellular stress affects A1AT protein expression |
| 急性西地那非给药可降低绵羊对诱发性心房颤动的易感性 |
denham, N. |
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N/A |
Acute sildenafil administration reduces susceptibility to induced atrial fibrillation in sheep |
| 多层记忆痕迹中的任务相关表征格式 |
Heinen, R. |
PDF |
N/A |
Task-relevant representational formats in multi-layered memory traces |
| 行为谱显示，大鼠对一种恐惧条件下的视觉线索表现出多样行为的组织能力。 |
Williams, D. C. |
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N/A |
Ethograms reveal a fear conditioned visual cue to organize diverse behaviors in rats |
| 人微小RNA-153-3p靶向特定的神经元基因，并与阿尔茨海默病的风险相关。 |
Wang, R. |
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N/A |
Human microRNA-153-3p targets specific neuronal genes and is associated with the risk of Alzheimer's disease. |
| 精神分裂症患者免疫细胞中IKZF1-IKZF2串联的双重打击调节特定症状 |
Ballasch, I. |
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N/A |
A double hit affecting the IKZF1-IKZF2 tandem in immune cells of schizophrenic patients regulate specific symptoms |
| 表观遗传适应驱动单核细胞在移植入视网膜后分化为类似小胶质细胞的细胞 |
Liu, J. |
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N/A |
Epigenetic adaptation drives monocyte differentiation into microglia-like cells upon engraftment into the retina |
| 用于可预测、精确的双水平调控哺乳动物重组蛋白表达的合成G四链体元件 |
Pohle, M. |
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N/A |
Synthetic G-quadruplex components for predictable, precise two-level control of mammalian recombinant protein expression |
| 肽激动剂解离和粘附G蛋白偶联受体失活的机制 |
Joshi, K. |
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N/A |
Mechanisms of peptide agonist dissociation and deactivation of adhesion G-protein-coupled receptors |
| 初级纤毛促进EMT诱导的三阴性乳腺癌肿瘤异质性和对治疗的抵抗性 |
Tessier, C. |
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N/A |
Primary cilia promote EMT-induced triple-negative breast tumor heterogeneity and resistance to therapy |
| NEK9敲除通过诱导ERK介导的癌细胞焦亡重塑多西他赛耐药性 |
Ansari, S. A. |
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N/A |
NEK9 ablation rewires docetaxel resistance through induction of ERK-mediated cancer cell pyroptosis |
| RAD50是一种潜在的乳腺癌诊断和预后生物标志物。 |
Chhatwal, K. S. |
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N/A |
RAD50 is a potential biomarker for breast cancer diagnosis and prognosis |
| 通过理性受体工程解锁扩展的鞭毛蛋白感知 |
Li, T. |
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N/A |
Unlocking expanded flagellin perception through rational receptor engineering |
| 高脂饮食对小鼠下丘脑反应的性别依赖性影响 |
Dreux, V. |
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N/A |
Sex-dependent effects of a high-fat diet on the hypothalamic response in mouse |
| TAAR1部分激动剂诱导的觉醒通过多巴胺能神经传递介导 |
Park, S. |
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N/A |
Wakefulness induced by TAAR1 partial agonism is mediated through dopaminergic neurotransmission |
| 通过电子断层扫描技术对脑内皮细胞的超微结构进行分析 |
Kotchetkov, P. |
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N/A |
Ultrastructural analysis of the brain endothelium by electron tomography |
| 在正常生理条件下，基于统计稳健性的轴突髓鞘单元模型及其在疾病状态中的应用 |
Gow, A. |
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N/A |
A Statistically-Robust Model Of The Axomyelin Unit Under Normal Physiologic Conditions With Application To Disease States |
| 分带运动适应相关的皮层-肌肉耦合的调制 |
Oshima, A. |
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N/A |
Modulation of cortico-muscular coupling associated with split-belt locomotor adaptation |
| 刺伤伤口引发实质性星形胶质细胞中的过渡放大祖细胞样表型 |
Ninkovic, J. |
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N/A |
Stab Wound Injury Elicits Transit Amplifying Progenitor-like Phenotype in Parenchymal Astrocytes |
| 通过蛋白质语言模型从氨基酸序列预测蛋白质半衰期 |
Sagawa, T. |
PDF |
N/A |
Prediction of Protein Half-lives from Amino Acid Sequences by Protein Language Models |
| 一个用于SubtiWiki的新框架，SubtiWiki是模式生物枯草芽孢杆菌的数据库 |
Elfmann, C. |
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N/A |
A new framework for SubtiWiki, the database for the model organism Bacillus subtilis |
| 识别、优先排序和可视化功能性启动子单核苷酸变异（SNVs）：使用复发无关的REMIND-Cancer管道和pSNV Hunter |
Abad, N. A. B. |
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N/A |
Identifying, Prioritizing, and Visualizing Functional Promoter SNVs with the Recurrence-agnostic REMIND-Cancer Pipeline and pSNV Hunter |
| 针对施万细胞EP2/cAMP纳米域以阻断疼痛但不阻断炎症 |
Nassini, R. |
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N/A |
Targeting the Schwann Cell EP2/cAMP Nanodomain to Block Pain but not Inflammation |
| 靶向细胞器中蛋白酶激活受体2信号的纳米药物提供持续镇痛效果 |
Teng, S. L. |
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N/A |
Nanomedicines targeting signaling of protease-activated receptor 2 in organelles provide sustained analgesia |
| 单细胞实验的顺序设计以识别基因表达的离散随机模型。 |
Cook, J. |
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N/A |
Sequential design of single-cell experiments to identify discrete stochastic models for gene expression. |
| 揭示种族间面孔感知背后的神经表征 |
Shoura, M. |
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N/A |
Revealing the neural representations underlying other-race face perception |
| 乳腺癌中驱动下丘脑-垂体-肾上腺轴功能障碍的脑-体反馈回路 |
Gomez, A. |
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N/A |
A brain-body feedback loop driving HPA-axis dysfunction in breast cancer |
| TAAR2-9敲除小鼠表现出觉醒度降低和快速眼动睡眠（REM睡眠）紊乱 |
Park, S. |
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N/A |
TAAR2-9 Knockout Mice Exhibit Reduced Wakefulness and Disrupted REM Sleep |
| 心脏、呼吸和胃的节律独立地调节皮层脊髓兴奋性。 |
Engelen, T. |
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N/A |
The cardiac, respiratory and gastric rhythms independently modulate corticospinal excitability |
| Parechovirus-3感染破坏了免疫代谢，并导致神经类器官中的谷氨酸兴奋性毒性 |
Capendale, P. E. |
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N/A |
Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids |
| 过敏原免疫后，2型常规树突状细胞中的IFN-I信号支持TH2和T滤泡辅助细胞的分化。 |
Webb, G. R. |
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N/A |
IFN-I signaling in type 2 conventional dendritic cells supports TH2 and T follicular helper differentiation after allergen immunization |
| 用于性别鉴定的高保真遗传标记，适用于大麻（Cannabis sativa）幼苗的性别鉴定。 |
Prentout, D. |
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N/A |
High fidelity genetic markers for sexing Cannabis sativa seedlings |
| 布朗运动数据增强：一种提升神经网络在纳米孔传感器性能的方法 |
Kipen, J. |
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N/A |
Brownian motion data augmentation: a method to push neural network performance on nanopore sensors |
| 糖尿病视网膜病变中自噬相关基因的鉴定与验证 |
Peng, W. |
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N/A |
Identification and Validation of Mitophagy-Related Genes in Diabetic Retinopathy |
| 量子力学预测Bicoid的解读时间不到一秒。 |
Lone, I. |
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N/A |
Quantum mechanics predicts Bicoid interpretation times of less than a second |
| 血小板PI3Kβ调控乳腺癌转移 |
Graff, R. C. |
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N/A |
Platelet PI3Kβ regulates breast cancer metastasis |
| RAD23A的减少可延长寿命并减轻TDP-43小鼠的病理症状 |
Xueshui, G. n. |
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N/A |
Reduction of RAD23A extends lifespan and mitigates pathology in TDP-43 mice |
| 去蜡人脑组织的定量细胞结构表型分析 |
Di Meo, D. |
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N/A |
Quantitative cytoarchitectural phenotyping of deparaffinized human brain tissues |
| 胆碱能反馈用于特定情境下对感觉表征的调节 |
Yu, B. |
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N/A |
Cholinergic feedback for context-specific modulation of sensory representations |
| 在观察者的大脑中：双稳态运动揭示了V1区域中尺度反馈调制的存在 |
Pizzuti, A. |
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N/A |
In the brain of the beholder: bi-stable motion reveals mesoscopic-scale feedback modulation in V1 |
| 早期至中期儿童非周期性脑电活动的纵向轨迹 |
Sacks, D. D. |
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N/A |
Longitudinal trajectories of aperiodic EEG activity in early to middle childhood |
| G-CSF和IL-6在严重病毒感染期间驱动髓系失调 |
Kajihara, K. |
PDF |
N/A |
G-CSF and IL-6 drive myeloid dysregulation during severe viral infection |
| BRUCE肝虚证通过损害肝细胞的线粒体代谢和激活肝星状细胞中的STAT3信号，在PTEN肝虚证的背景下加剧了MASLD/MASH。 |
Che, L. |
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N/A |
BRUCE liver-deficiency potentiates MASLD/MASH in PTEN liver-deficient background by impairment of mitochondrial metabolism in hepatocytes and activation of STAT3 signaling in hepatic stellate cells |
| 中东呼吸综合征冠状病毒的持续演变，沙特阿拉伯王国，2023-2024年 |
Hassan, A. M. |
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N/A |
Ongoing evolution of Middle East Respiratory Syndrome Coronavirus, Kingdom of Saudi Arabia, 2023-2024 |
| SCAMPI：一种可扩展的统计框架，用于利用跨性状相关性进行全基因组交互测试 |
Bian, S. |
PDF |
N/A |
SCAMPI: A scalable statistical framework for genome-wide interaction testing harnessing cross-trait correlations |
| 亚细胞水平空间转录组学与PHOTON |
Rajachandran, S. |
PDF |
N/A |
Subcellular Level Spatial Transcriptomics with PHOTON |
| 通过结合高通量筛选实验与非靶向代谢组学方法，探究美洲接骨木化合物在抗氧化、抗病毒和抗菌特性方面的潜力。 |
Dwikarina, A. |
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N/A |
Exploring American Elderberry Compounds for Antioxidant, Antiviral, and Antibacterial Properties Through High-Throughput Screening Assays Combined with Untargeted Metabolomics |
| 快速生产来自类精干细胞的改良牛羊 |
Yang, L. |
PDF |
N/A |
Rapid production of modified cattle and sheep from spermatid-like stem cells |
| 随机取向的微槽水凝胶引导细胞运动，调节运动速度，并控制细胞扩散的方向性。 |
Ghosh, B. |
PDF |
N/A |
Randomly oriented microgrooved hydrogel guides cellular motility, modulates speed, and governs directionality of cellular spread |
| 手性组氨酸富集肽凝聚体增强抗原向T细胞的递送 |
Pramanik, U. |
PDF |
N/A |
Enantiomeric histidine-rich peptide coacervates enhance antigen delivery to T cells |
| 动态关联（Associations on the Fly）是一项新功能，旨在促进对Open Targets平台证据的探索。 |
Cruz-Castillo, C. |
PDF |
N/A |
Associations on the Fly, a new feature aiming to facilitate exploration of the Open Targets Platform evidence |
| 通过局部几何生成进行三维分子预训练 |
Sun, Y. |
PDF |
N/A |
3D Molecular Pretraining via Localized Geometric Generation |
| 不同的基质细胞群定义了B细胞急性淋巴母细胞白血病的微环境 |
Blanco, M. N. F. |
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N/A |
Distinct Stromal Cell Populations Define the B-cell Acute Lymphoblastic Leukemia Microenvironment |
| 优化形状定义微粒的制备以实现持续药物递送：“少即是多”范式 |
Murgia, D. |
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N/A |
Optimizing The Fabrication Of Shape-Defined Microparticles For Sustained Drug Delivery: The 'Less Is More' Paradigm |
| 缺血再灌注后外肾髓优先损伤依赖于高氧化代谢 |
Arnoux, G. |
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N/A |
The preferential injury of outer renal medulla after ischemia-reperfusion relies on high oxidative metabolism |
| 高剂量大麻二酚预处理对抗阿片类药物引起的持续性呼吸暂停的概念验证 |
Wiese, B. M. |
PDF |
N/A |
Proof of Concept for High-Dose Cannabidiol Pretreatment to Antagonize Opioid Induced Persistent Apnea |
| 全身麻醉激活的中央杏仁核神经元在神经病理性疼痛的急性期和晚期阶段的不同作用 |
Zhao, J. |
PDF |
N/A |
Distinct roles of general anesthesia activated CeA neurons in acute versus late phase of neuropathic pain |
| 物体非刚性的各向异性：皮层各向异性的高级知觉后果 |
Maruya, A. |
PDF |
N/A |
Anisotropy of object non-rigidity: High-level perceptual consequences of cortical anisotropy |
| 致病性微生物群通过改变能量代谢破坏脑类器官的完整结构 |
Isik, M. |
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N/A |
Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism |
| 糖脂质系统对α-突触核蛋白传播的影响：水通道蛋白-4和肌营养不良蛋白相关蛋白复合物的作用 |
Lopes, D. M. |
PDF |
N/A |
Influence of the Glymphatic System on α-Synuclein Propagation: Role of Aquaporin-4 and the Dystrophin-Associated Protein Complex |
| 使用即兴演讲（IMPRO）的新压力诱发协议的有效性 |
Saskovets, M. |
PDF |
N/A |
Validity of a New Stress Induction Protocol using Speech Improvisation (IMPRO) |
| 通过脑机接口对皮层波进行操作性条件反射 |
Dogadov, A. |
PDF |
N/A |
Operant conditioning of cortical waves through a brain-machine interface |
| PLCγ2的保护性变体通过增强有益的微胶质细胞功能，减轻了与阿尔茨海默病相关的病理。 |
Takalo, M. |
PDF |
N/A |
Protective variant in PLCgamma2 mitigates Alzheimer's disease associated pathology via enhancing beneficial microglia functions |
| 成年少突胶质细胞生成通过ADAMTS4重塑血脑屏障来调控弓状核神经元的葡萄糖感应 |
Buller, S. |
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N/A |
Adult oligodendrogenesis gates arcuate neuronal glucose sensing through remodelling of the blood-hypothalamus barrier via ADAMTS4 |
| 胰岛淀粉样蛋白破坏MHC II类抗原呈递，并保护NOD小鼠免受自身免疫性糖尿病的影响。 |
Denroche, H. C. |
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N/A |
Islet amyloid disrupts MHC Class II antigen presentation and protects NOD mice from autoimmune diabetes. |
| 单细胞和时空转录组分析揭示委内瑞拉马脑炎病毒感染后脑部免疫浸润情况 |
Rangel, M. |
PDF |
N/A |
Single-cell and spatiotemporal transcriptomic profiling of brain immune infiltration following Venezuelan equine encephalitis virus infection |
| SARS-CoV-2蛋白ORF3a诱导溶酶体膜的Atg8化 |
Ajnar, D. |
PDF |
N/A |
SARS-CoV-2 protein ORF3a induces Atg8ylation of lysosomal membranes |
| 利用相关性和机制性物种分布模型预测当前和未来环境及气候变化下的虫媒疾病风险：以英国西尼罗河病毒为例的研究。 |
Withers, A. J. |
PDF |
N/A |
Using correlative and mechanistic species distribution models to predict vector-borne disease risk for the current and future environmental and climatic change: a case study of West Nile Virus in the UK. |
| 评估高致病性禽流感H5病毒在法国肉鸡和蛋鸡生产网络中传播的风险 |
Hautefeuille, C. |
PDF |
N/A |
Assessing the risk of highly pathogenic avian influenza H5 viruses spread within French broiler and layer production networks |
| 苔藓藻基因组：绿色植物多细胞化和陆地化的替代机制 |
Caisova, L. |
PDF |
N/A |
The Draparnaldia genome: alternative mechanisms for multicellularity and terrestrialization in green plants |
| EBAX-1/ZSWIM8 破坏 miRNA，导致捕食特征的跨代记忆 |
Quiobe, S. P. |
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N/A |
EBAX-1/ZSWIM8 destabilizes miRNAs resulting in transgenerational memory of a predatory trait |
| 长链非编码RNA TAAL是糖尿病视网膜病变中Tie1介导的血管功能的调节因子 |
Ranjan, G. |
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N/A |
LncRNA TAAL is a Modulator of Tie1-Mediated Vascular Function in Diabetic Retinopathy |
| 单倍型解析的基因组组装为新疆最古老的葡萄品种（木纳格）的基因组构成提供了深入见解。 |
Zhong, H. |
PDF |
N/A |
Haplotype-resolved assemblies provide insights into genomic makeup of the oldest grapevine cultivar (Munage) in Xingjiang |
| DiatOmicBase是一个以基因为中心的平台，用于挖掘硅藻基因组间的功能组学数据。 |
Villar, E. |
PDF |
N/A |
DiatOmicBase, a gene-centered platform to mine functional omics data across diatom genomes |
| 内皮糖萼的成熟度水平调节其与带电纳米材料的相互作用 |
Bridges, C. |
PDF |
N/A |
The level of endothelial glycocalyx maturity modulates interactions with charged nano-materials |
| 蛋白质冠组成因果分析：磷脂酰胆碱通过蛋白质组学增强血浆蛋白质组谱分析 |
Rafieioskouei, A. |
PDF |
N/A |
Causality Analysis of Protein Corona Composition: Phosphatidylcholine-Enhances Plasma Proteome Profiling by Proteomics |
| ScReNI：通过整合scRNA-seq和scATAC-seq数据进行单细胞调控网络推断 |
Xu, X. |
PDF |
N/A |
ScReNI: single-cell regulatory network inference through integrating scRNA-seq and scATAC-seq data |
| LoVis4u：用于比较基因组的位点可视化工具 |
Egorov, A. A. |
PDF |
N/A |
LoVis4u: Locus Visualisation tool for comparative genomics |
| SVbyEye：一种用于描述全基因组组装间结构变异的视觉工具 |
Porubsky, D. |
PDF |
N/A |
SVbyEye: A visual tool to characterize structural variation among whole genome assemblies |
| 一种高通量表型筛选结合基于超大规模深度学习的虚拟筛选揭示了新型抗菌化合物骨架 |
Scalia, G. |
PDF |
N/A |
A high-throughput phenotypic screen combined with an ultra-large-scale deep learning-based virtual screening reveals novel scaffolds of antibacterial compounds |
| 考古记录中β-乳球蛋白肽的存续性：脆弱性与序列变异 |
Fonseca, B. |
PDF |
N/A |
The Survival of β-lactoglobulin Peptides in the Archaeological Record: Vulnerability vs. Sequence Variation |
| 光惰性气体对脂质过氧化引起的化学发光可能的作用机制 |
Oliynyk, I. |
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N/A |
Possible Mechanisms Of Action Of Light Inert Gases On Chemiluminescence Arising As A Result Of Lipid Peroxidation |
| BST2在癌症进展过程中诱导血管平滑肌细胞的可塑性和表型转换 |
Bell, C. |
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BST2 induces vascular smooth muscle cell plasticity and phenotype switching during cancer progression |
| 癌症适应性治疗周期设计与稳定性：确定性与随机性模型 |
Vilela, Y. G. |
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On the design and stability of cancer adaptive therapy cycles: deterministic and stochastic models |
| 骨髓中的转移性肿瘤细胞与配对的神经母细胞瘤肿瘤不同，并包含具有治疗抵抗特性的亚群。 |
Hochheuser, C. |
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Metastatic tumor cells in bone marrow differ from paired neuroblastoma tumor and contain subsets with therapy-resistant characteristics |
| 使用深度学习从静息状态功能连接预测任务激活图 |
Madsen, S. J. |
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Predicting Task Activation Maps from Resting-State Functional Connectivity using Deep Learning |
| 增强初级视觉皮层与身体选择性皮层之间的前向连接，减少任务无关维度对身体判断的干扰 |
Gandolfo, M. |
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Boosting forward connectivity between primary visual and body selective cortex reduces interference of task irrelevant dimensions on body judgements |
| ARHGEF3调控毛囊形态发生 |
Laurin, M. |
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ARHGEF3 Regulates Hair Follicle Morphogenesis |
| 有益根际细菌和病毒感染调节大豆代谢组，并影响病毒媒介Epilachna varivestis的取食偏好。 |
Pulido, H. |
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Beneficial rhizobacteria and virus infection modulate the soybean metabolome and influence the feeding preferences of the virus vector Epilachna varivestis. |
| 足部放置控制在跨物种的稳定运动中起着基础作用 |
De Comite, A. |
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Foot placement control underlies stable locomotion across species |
| 评估携带SUB1和DRO1基因的IR64水稻近等基因系对逆境的耐受性 |
Sakagami, J.-I. |
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Evaluation of stress tolerance in IR64 rice near-isogenic lines carrying SUB1 and DRO1 genes |
| 对英国市场上销售的基于植物和肉类成分的完整干狗粮的营养分析 |
Brociek, R. A. |
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Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK |
| 促炎介质使小鼠感觉神经元中的瞬时受体电位梅拉司林3型阳离子通道（TRPM3）信号传导敏感化 |
Aguilera-Lizarraga, J. |
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Pro-inflammatory mediators sensitise Transient Receptor Potential Melastatin 3 cation channel (TRPM3) signalling in mouse sensory neurons |
| 脊髓感觉运动回路在侧胸半横断后控制系带和分带步态相位持续时间的操作 |
Rybak, I. A. |
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Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection |
| 土壤氧化还原作用驱动病毒-宿主群落动态及热带雨林土壤中植物生物量的降解 |
Trubl, G. |
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Soil redox drives virus-host community dynamics and plant biomass degradation in tropical rainforest soils |
| 海洋酵母对基于昆布多糖的基质的利用和降解表明它们在微生物循环动力学中具有生态位特异性作用。 |
Reich, M. |
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Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics. |
| 表面介导的噬菌体防御对细菌间拮抗作用产生了适应性权衡 |
Tsai, C.-E. |
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Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism |
| tRNA赖氨酰化对于恶性疟原虫顶质体中发现的最低翻译系统至关重要。 |
Elahi, R. |
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tRNA lysidinylation is essential for the minimal translation system found in the apicoplast of Plasmodium falciparum |
| 计算机分析显示，常用的PCR检测方法对肠道病毒物种的靶向性存在差异。 |
Trinh, V. N. |
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In silico analysis reveals differential targeting of enterovirus species by commonly used PCR assays |
| 应激诱导小蛋白的翻译谱分析揭示了不同信号系统之间意想不到的联系 |
Vellappan, S. |
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Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems |
| 新加坡受试者粪便样本中分离的三种Acutalibacteraceae细菌的基因组重建与饮食反应评估。 |
Park, M. A. |
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Genomic Reconstruction and Dietary Response Assessment of Three Acutalibacteraceae Bacteria Isolated from Fecal Samples of Singapore Subjects. |
| 利用膜编辑结合邻近标记技术揭示的调控磷脂酸稳态的动态网络 |
Tei, R. |
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Dynamic network regulating phosphatidic acid homeostasis revealed using membrane editing coupled to proximity labeling |
| Nf1对睡眠行为的影响是通过SARM1依赖的NAD+代谢缺陷引起的饥饿所介导的。 |
Sofela, F. A. |
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Effects of Nf1 on sleep behavior are mediated through starvation caused by deficits in SARM1 dependent NAD+ metabolism. |
| 解释预测区间和分布以解码元分析中的生物普遍性 |
Yang, Y. |
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Interpreting prediction intervals and distributions for decoding biological generality in meta-analyses |
| 通过结肠发酵和小麦阿拉伯木聚糖的酶催化产生生物活性结构基序：体外、计算机模拟和功能分析提供的与Toll样受体相互作用的证据 |
Guerreiro, C. d. A. |
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Production of bioactive structural motifs from wheat arabinoxylan via colonic fermentation and enzymatic catalysis: evidence of interaction with toll-like receptors from in vitro, in silico and functional analysis |
| 鞘氨醇激酶1在脂肪来源干细胞中被糖皮质激素诱导，并增强糖皮质激素介导的脂肪扩张信号传导。 |
Lambert, J. M. |
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Sphingosine kinase 1 is induced by glucocorticoids in adipose derived stem cells and enhances glucocorticoid mediated signaling in adipose expansion. |
| 线粒体脂肪酸氧化受红光照射刺激 |
Herrera, M. A. |
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Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation |
| 异常剪接体中间体在其解体过程中的结构 |
Soni, K. |
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Structures of aberrant spliceosome intermediates on their way to disassembly |
| 机器学习增强的分子动力学模拟（MD）揭示了ZTPriboswitch配体的亲和力与激活之间的脱节现象。 |
Fullenkamp, C. R. |
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Machine learning-augmented molecular dynamics simulations (MD) reveal insights into the disconnect between affinity and activation of ZTPriboswitch ligands |
| 质子化/去质子化驱动的低电位铁氧还蛋白氧化还原稳定性的开关 |
Wada, K. |
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Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin |
| 分子转子为α-突触核蛋白聚集物的形成和转化机制提供了深入见解。 |
Allerton, S. C. |
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Molecular rotors provide insight into the mechanism of formation and conversion of α-synuclein aggregates |
| 一种针对糖体膜生物合成的抑制剂可杀死利什曼原虫寄生虫。 |
Chou, S.-E. |
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An inhibitor targeting glycosome membrane biogenesis kills Leishmania parasites |
| AI生成的小型活页夹提升了主要编辑效果 |
Park, J.-C. |
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AI-generated small binder improves prime editing |
| 仿生病毒样颗粒调控细胞功能 |
Maayouf, H. |
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Biomimetic Virus-Like Particles to control cell functions |
| 计算机模拟研究：选择性生物碱作为阿尔茨海默病β和γ-分泌酶双重抑制剂 |
Onifade, I. |
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In silico study of selected alkaloids as dual inhibitors of β and γ-Secretases for Alzheimer's disease |
| 映射和建模内在神经时间尺度的年龄相关变化 |
Wu, K. |
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Mapping and Modeling Age-Related Changes in Intrinsic Neural Timescales |
| 利用预训练的深度蛋白质语言模型预测肽段的碰撞截面 |
Nakai-Kasai, A. |
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Leveraging Pretrained Deep Protein Language Model to Predict Peptide Collision Cross Section |
| 极端嗜热、分解木质纤维素的厌氧细菌Anaerocellum bescii（前称Caldicellulosiruptor bescii）中的麦芽糊精转运 |
Tjo, H. |
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Maltodextrin Transport in the Extremely Thermophilic, Lignocellulose Degrading Bacterium Anaerocellum bescii (f. Caldicellulosiruptor bescii) |
| 振动触觉耳迷走神经刺激在人类中改变边缘系统连接：一项初步研究 |
Donovan, K. M. |
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Vibrotactile auricular vagus nerve stimulation alters limbic system connectivity in humans: A pilot study |