| 进化上多样的穴样内陷蛋白共享一个围绕两亲性圆盘构建的共同结构框架。 |
Han, B. |
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Evolutionarily diverse caveolins share a common structural framework built around amphipathic discs |
| 综合确定与亨廷顿病相关的突变型亨廷顿蛋白外显子1纤维的原子结构 |
Bagherpoor Helabad, M. |
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Integrative determination of the atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington's disease |
| 人类病原体肺炎支原体和生殖支原体粘附复合体的动力学 |
Kawamoto, A. |
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N/A |
Dynamics of the adhesion complex of the human pathogens Mycoplasma pneumoniae and Mycoplasma genitalium |
| 细胞丝状体在细菌聚集和集群-集群组装中的作用 |
Charlton, S. G. V. |
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N/A |
The role of cellular filamentation in bacterialaggregation and cluster-cluster assembly |
| 使用线性图像解码器和非线性噪声抑制从人类大脑活动中重建的无语义视觉图像 |
Li, Q. |
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Visual Image Reconstructed Without Semantics from Human Brain Activity Using Linear Image Decoders and Nonlinear Noise Suppression |
| 工程化酵母细胞模拟CD19+癌症，以控制CAR T细胞的激活 |
Deichmann, M. |
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Engineered yeast cells simulating CD19+ cancers to control CAR T cell activation |
| 通过竞争性蛋白质二聚化网络进行计算的原理 |
Parres-Gold, J. |
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N/A |
Principles of Computation by Competitive Protein Dimerization Networks |
| 三种RING蛋白的不同且相互依赖的功能调控哺乳动物减数分裂中的重组过程。 |
Ito, M. |
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Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis |
| 普罗克拉斯提斯图（Prokrustean Graph）：一种用于快速k-mer大小分析的子串索引 |
Park, A. |
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Prokrustean Graph: A substring index for rapid k-mer size analysis |
| 一种动态系统方法用于最佳觅食 |
Chaturvedi, S. |
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A Dynamical Systems Approach to Optimal Foraging |
| 表征差异成分分析（ReDisCA） |
Ossadtchi, A. |
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Representational dissimilarity component analysis (ReDisCA) |
| 鉴定调控腭发育的新基因 |
Bhaskar, A. |
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Identification of novel genes regulating the development of the palate |
| CD4+ T细胞在急性水缺乏型干眼模型中驱动角膜神经损伤，但并不引起上皮病变 |
Vereertbrugghen, A. |
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CD4+ T cells drive corneal nerve damage but not epitheliopathy in an acute aqueous-deficient dry eye model |
| 改进六倍体小麦的基因组选择：亚基因组加性和上位性模型 |
Tessele, A. |
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N/A |
Improving genomic selection in hexaploid wheat with sub-genome additive and epistatic models |
| 前庭眼动反射的成熟并不依赖于感觉输入 |
Leary, P. |
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Sensation is Dispensable for the Maturation of the Vestibulo-ocular Reflex |
| PGE2合成/反应通路的破坏可抑制程序性细胞死亡-1（Pd-1）缺陷的高脂血症小鼠的动脉粥样硬化形成。 |
Ricciotti, E. |
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Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice |
| 延长酶和去饱和酶编码基因的表达塑造了蜜蜂表皮碳氢化合物的特征 |
Rodriguez-Leon, D. S. |
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Expression of elongase- and desaturase-encoding genes shapes the cuticular hydrocarbon profiles of honey bees |
| GBA1 突变改变了神经元的放电和结构，调节了多巴胺神经元中的 VGLUT2 和 CRYAB |
Rodriguez-Traver, E. |
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GBA1 mutations alter neuronal firing and structure, regulating VGLUT2 and CRYAB in dopamine neurons |
| 神经肽催产素通过调节血流动力学和通透性，促进其从大脑到外周的摄取。 |
Rajamannar, P. |
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Neuropeptide oxytocin facilitates its own brain-to-periphery uptake by regulating blood flow dynamics and permeability |
| 睡眠期间，脑淋巴系统清除功能得到增强。 |
Kroesbergen, E. |
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N/A |
Glymphatic clearance is enhanced during sleep |
| SCRATCH：一种可编程、开源硬件的台式机器人，能够自动刮擦培养的组织，以研究细胞迁移、愈合和组织塑形。 |
Lin, Y. |
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SCRATCH: A programmable, open-hardware, benchtop robot that automatically scratches cultured tissues to investigate cell migration, healing, and tissue sculpting. |
| 不那么自私：可移动元件助力适应气候变化 |
Potapenko, E. V. |
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Not so selfish: transposable elements fuel adaptation to climate change |
| 线粒体过度活跃和活性氧驱动对黄热病病毒-17D减毒活疫苗的先天免疫反应 |
Muccilli, S. G. |
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Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine |
| 鉴定影响CRISPR相关转座酶的蛋白质以增强基因组编辑 |
Song, L. |
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Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing |
| 有丝分裂驱动蛋白-5是轴突生长的动态制动器 |
Lu, W. |
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'Mitotic' kinesin-5 is a dynamic brake for axonal growth |
| 喷墨打印的石墨烯多电极阵列：体外心脏电生理学的可及平台 |
Lumpuy-Castillo, J. |
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Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology |
| 番茄和茄子幼苗茎部软化和半透明形态学特征因感染拉尔氏假单胞菌F1C1所致 |
Bhuyan, S. |
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Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1 |
| 通过明胶-弹性纤维增强水凝胶进行阴道组织工程 |
Zambuto, S. G. |
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Vaginal Tissue Engineering via Gelatin-Elastin Fiber-Reinforced Hydrogels |
| ARHGEF3调节毛囊形态发生 |
Kalyanakrishnan, K. |
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ARHGEF3 Regulates Hair Follicle Morphogenesis |
| 应激诱导小蛋白的翻译组学分析揭示了不同信号系统之间出乎意料的联系 |
Vellappan, S. |
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Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems |
| 微生物群通过保护卵巢储备来延长生殖寿命 |
Munyoki, S. K. |
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The microbiota extends the reproductive lifespan by safeguarding the ovarian reserve |
| 人类胎儿期前颅窝形态学评估及其临床意义。 |
Derkowski, W. |
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Morphometric evaluation of the anterior cranial fossa during the prenatal stage in humans and its clinical implications. |
| 长末端重复序列逆转录转座子通过增强子捕获产生类似病毒的颗粒，导致发育中的肢体表型 |
Glaser, J. |
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Enhancer adoption by an LTR retrotransposongenerates viral-like particles causingdevelopmental limb phenotypes |
| 适度激活线粒体未折叠蛋白反应可延长寿命，但不会增加对压力的抵抗力。 |
Di Pede, A. |
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Mild activation of the mitochondrial unfolded protein response increases lifespan without increasing resistance to stress |
| 模拟有蹄类动物的夜间协调节律 |
Ukrow, J. |
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Modelling coordinated nocturnal rhythms in ungulates |
| 蓝斑的α-2受体激动作用会损害由负向预测误差驱动的学习过程。 |
Lui, S. K. C. |
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Alpha-2 agonism of the locus coeruleus impairs learning driven by negative prediction error |
| 使用模糊聚类对分级动物发声进行无监督分类 |
Benti, B. |
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Unsupervised classification of graded animal vocalisations using fuzzy clustering |
| 利用人类测序、斑马鱼筛选和蛋白质结合微阵列技术鉴定眼部先天性颅神经运动神经元疾病的基因 |
Jurgens, J. A. |
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Gene identification for ocular congenital cranial motor neuron disorders using human sequencing, zebrafish screening, and protein binding microarrays |
| 老年人中的优越感错觉：楔前叶的体积和功能连接性 |
Shidei, Y. |
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Superiority illusion in older adults: volume and functional connectivity of the precuneus |
| 前额叶皮层和循环神经网络中反转学习的神经动力学 |
Kim, C. M. |
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Neural dynamics of reversal learningin the prefrontal cortex and recurrent neural networks |
| Cav3.1是POMC神经元中的亮氨酸传感器，介导食欲抑制和体重减轻。 |
Tsang, A. H. |
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Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and weight loss |
| 数据驱动的1H-MRS基集成分的确定 |
Davies-Jenkins, C. W. |
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Data-driven determination of 1H-MRS basis set composition |
| 目标记忆再激活引发了与纺锤波相关的时间压缩再激活 |
Abdellahi, M. E. A. |
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Targeted memory reactivation elicits temporally compressed reactivation linked to spindles |
| 元意识、心智游移以及对“默认”外部和内部注意定向的控制 |
Christian, I. R. |
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Meta-awareness, mind-wandering, and the control of 'default' external and internal orientations of attention |
| 在小脑的Crus I和II区域，浦肯野细胞在猴子学习基于强化的视动关联任务时，既编码视觉刺激，也编码即将做出的选择。 |
Ipata, A. |
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Purkinje cells in Crus I and II encode the visual stimulus and the impending choice as monkeys learn a reinforcement based visuomotor association task |
| 用于分类神经元形态的深度学习：结合拓扑数据分析与图神经网络 |
Kanari, L. |
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Deep learning for classifying neuronal morphologies: combining topological data analysis and graph neural networks |
| 超越脑电图起始瞬变：对模式眩光刺激的恒定呈现和消失的超兴奋性的敏感化和习惯化 |
Jefferis, T. |
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Beyond EEG Onset Transients: Sensitisation and Habituation of Hyper-excitation to Constant Presentation and Offset ofPattern-Glare Stimuli |
| 通过放电率适应产生交替θ波扫描的系统模型 |
Ji, Z. |
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A systems model of alternating theta sweeps via firing rate adaptation |
| 石榴籽油通过Keap1/Nrf2/NQO1通路对大鼠皮质短暂性大脑中动脉闭塞的预防作用 |
Li, D. |
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Preventive Effects of Pomegranate Seed Oil on Transient Middle Cerebral Artery Occlusion via the Keap1/Nrf2/NQO1 Pathway in the rats Cortex |
| 小胶质细胞中的BRD4表达支持T细胞招募进入中枢神经系统，并加剧实验性自身免疫性脑脊髓炎（EAE）。 |
Dey, A. |
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BRD4 expression in microglia supports recruitment of T cells into the CNS and exacerbates EAE |
| 反馈在应对渐进和突发视觉-本体感觉线索冲突中的作用 |
Babu, R. |
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The role of feedback in responding to gradual and abrupt visuo-proprioceptive cue conflict |
| 用于视觉、眼动追踪和脑电图研究的高速OLED显示器，以实现精确刺激 |
Dimigen, O. |
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N/A |
A high-speed OLED monitor for precise stimulation in vision, eye-tracking, and EEG research |
| 发育过程中GABA水平降低导致斑马鱼幼体顶盖的连接性增加 |
Liu, Y. |
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Decreased GABA levels during development result in increased connectivity in the larval zebrafish tectum |
| 昼夜节律的高度明显性与男性的负面情绪特质以及对惩罚相关信息增强的神经处理有关。 |
Scislewska, P. |
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High distinctness of circadian rhythm is related to negative emotionality and enhanced neural processing of punishment-related information in men |
| 前扣带回（ACC）印记神经元的早期内在可塑性决定了记忆的形成和精确性 |
Hadzibegovic, S. |
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Early intrinsic plasticity of ACC engram neurons defines memory formation and precision |
| 经颅电刺激可调节前庭系统 |
Laakso, I. |
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N/A |
Transcranial electrical brain stimulation modulates the vestibular system |
| AAV介导的proneural因子表达在体内刺激成年Müller胶质细胞的神经发生。 |
Pavlou, M. |
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AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo. |
| 不同行为相关的刺激在嗅觉系统中引发不同形式的适应 |
Nikolaev, A. |
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Different behaviourally relevant stimuli evoke different forms of adaptation in the olfactory system |
| 在拉福拉病（一种严重的进行性肌阵挛性癫痫）的小鼠模型中，谷氨酸能和GABA能信号通路中的胶质细胞改变 |
Viana, R. |
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Glial alterations in the glutamatergic and GABAergic signaling pathways in a mouse model of Lafora disease, a severe form of progressive myoclonus epilepsy |
| 相关和反相关双眼视差调节人脑视觉皮层中的GABA+和谷氨酸/谷氨酰胺浓度 |
Matuszewski, J. |
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Correlated and Anticorrelated Binocular Disparity Modulate GABA+ and Glutamate/glutamine Concentrations in the Human Visual Cortex |
| 慢性中风中异常μ节律状态相关的皮层和皮层脊髓反应 |
Wischnewski, M. |
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N/A |
Abnormal mu rhythm state-related cortical and corticospinal responses in chronic stroke |
| 通过放电率适应动态调制海马回放序列 |
Ji, Z. |
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N/A |
Dynamical Modulation of Hippocampal Replay Sequences through Firing Rate Adaptation |
| 在帕金森病中，人类皮层-基底神经节网络在运动序列启动期间的学习相关振荡动力学 |
Presbrey, K. N. |
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Learning-related oscillatory dynamics in the human cortico-basal ganglia network during motor sequence initiation in Parkinson's Disease |
| 病毒介导的传出抑制增强可减少野生型小鼠耳蜗的声损伤。 |
Slika, E. |
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Virally-Mediated Enhancement of Efferent Inhibition Reduces Acoustic Trauma in Wild Type Murine Cochleas. |
| Track-A-Worm 2.0：用于量化秀丽隐杆线虫运动、弯曲、睡眠及动作电位特性的软件套件 |
Vedantham, K. |
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N/A |
Track-A-Worm 2.0: A Software Suite for Quantifying Properties of C. elegans Locomotion, Bending, Sleep, and Action Potentials |
| 量化生物物理因素对通过残余功能网络塑造大脑交流的影响 |
Nakuci, J. |
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N/A |
Quantifying the influence of biophysical factors in shaping brain communication through remnant functional networks |
| 重复性磁刺激作用于运动皮层，通过抑制皮层内抑制的上调，损害平衡任务的巩固。 |
Egger, S. |
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Repetitive magnetic stimuli over the motor cortex impair consolidation of a balance task by suppressing up-regulation of intracortical inhibition |
| 皮质内注射免疫检查点抑制剂促进单核细胞/巨噬细胞浸润，并恢复AD小鼠模型中的小胶质细胞功能和神经元活动 |
Park, T. |
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Intracortical injection of immune checkpoint inhibitor promotes monocyte/macrophage infiltration and restores microglial function and neuronal activity in an AD mouse model |
| 用于离体和在体活细胞成像的等渗和微创光学透明介质 |
Inagaki, S. |
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N/A |
Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo |
| 横断面脑龄评估在预测未来脑变化方面存在局限性。 |
Korbmacher, M. |
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Cross-sectional brain age assessments are limited in predicting future brain change |
| SMN缺乏在脊髓性肌肉萎缩症的SMN{triangleup}7小鼠模型中，引发了早期非萎缩性肌病，导致骨骼肌纤维的收缩和兴奋耦合机制发生改变。 |
Berciano, M. T. |
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SMN deficiency induces an early non-atrophic myopathy with alterations in the contractile and excitatory coupling machinery of skeletal myofibers in the SMN{triangleup}7 mouse model of spinal muscular atrophy |
| 在猕猴下丘中视觉诱发活动与听觉反应的变量调制 |
Schmehl, M. N. |
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N/A |
Visually-evoked activity and variable modulation of auditory responses in the macaque inferior colliculus |
| 在谷氨酸能神经元中失活Ndufs4揭示了Leigh综合征小鼠模型中吞咽呼吸失调 |
Huff, A. D. |
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Ndufs4 inactivation in glutamatergic neurons reveals swallow-breathing discoordination in a mouse model of Leigh Syndrome |
| 人类NLRP3炎症小体激活导致在微管组织中心形成凝聚物 |
Wang, J. |
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Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center |
| 秀丽隐杆线虫中的体细胞转甲状腺素相关蛋白通过维持精子完整性和适时排卵来调控生殖寿命 |
Wu, T. |
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N/A |
Somatic Transthyretin-Related Proteins in C. elegans Govern Reproductive Longevity by Sustaining Sperm Integrity and Timely Ovulation |
| 从胚胎鼻干细胞重建功能性嗅觉感觉组织 |
Suzuki, K. |
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N/A |
Reconstruction of functional olfactory sensory tissue from embryonic nasal stem cells |
| 果蝇雌激素相关受体促进幼虫脂肪体内的甘油三酯储存 |
Fasteen, T. D. |
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N/A |
The Drosophila Estrogen-Related Receptor promotes triglyceride storage within the larval fat body |
| 普遍存在的有方向性选择发现，实现了古DNA揭示人类适应性的承诺。 |
Akbari, A. |
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N/A |
Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation |
| 肌梭为运动序列提供灵活的感觉反馈。 |
Olson, W. P. |
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N/A |
Muscle spindles provide flexible sensory feedback for movement sequences |
| 基于正念的神经反馈：对EEG和fMRI研究的系统综述 |
Treves, I. N. |
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N/A |
Mindfulness-based Neurofeedback: A Systematic Review of EEG and fMRI studies |
| 在自发活动期间，神经血管脉冲响应函数（IRF）在不同皮质区域差异性地反映了内在的神经调节作用。 |
Rauscher, B. C. |
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N/A |
Neurovascular Impulse Response Function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions |
| 在记忆回忆和视觉感知过程中，对手的视觉空间编码结构在脑内侧顶叶皮层中进行反应。 |
Scrivener, C. L. |
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N/A |
Opponent visuospatial coding structures responses during memory recall and visual perception in medial parietal cortex |
| 自由生活的旋毛虫（Strongyloides）物种生命阶段的温度感觉行为有助于其在热带环境中的寄生。 |
Gregory, B. T. |
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N/A |
Thermosensory behaviors of the free-living life stages of Strongyloides species support parasitism in tropical environments |
| 自由生活的旋毛虫生命阶段的温度感应行为有助于其在热带环境中的寄生。 |
Gregory, B. T. |
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N/A |
Thermosensory behaviors of the free-living life stages of Strongyloides species support parasitism in tropical environments |
| 根据过去的和当前的照顾经历，对依恋模式叙事的神经和言语反应有所不同。 |
Lee, C. S. |
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N/A |
Neural and verbal responses to attachment-schema narratives differ based on past and current caregiving experiences |
| 杏仁核对不确定性下动态模型仲裁的贡献 |
Woo, J. H. |
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N/A |
Contribution of amygdala to dynamic model arbitration under uncertainty |
| 结合转录组学、连接性和活性分析，利用高度放大的多重原位杂交技术（hamFISH）对内侧杏仁核进行研究 |
Edwards, M. D. |
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N/A |
Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH) |
| 海马结构中以自我为中心的社会知识的锚定与调整 |
Rodriguez Aramendia, M. |
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N/A |
Egocentric anchoring-and-adjustment of social knowledge in the hippocampal formation |
| SNc多巴胺能神经元中PKA-RIIβ水平的年龄相关性下降是PD发病的基础 |
Zhao, Y. |
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N/A |
Age-related decline of PKA-RIIβ level in SNc dopaminergic neurons underlies PD pathogenesis |
| 内源性G蛋白信号调节因子14（RGS14）抑制雌性小鼠中可卡因诱导的情感动机行为 |
Bramlett, S. N. |
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N/A |
Endogenous Regulator of G protein Signaling 14 (RGS14) suppresses cocaine-induced emotionally motivated behaviors in female mice |
| 使用物理信息神经网络建模感觉运动处理 |
Perez Rotondo, A. |
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N/A |
Modeling Sensorimotor Processing with Physics-Informed Neural Networks |
| 大麻和精神病对多巴胺系统的汇聚效应：一项针对大麻使用障碍和首发精神分裂症的纵向神经黑色素敏感MRI研究。 |
Ahrens, J. |
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N/A |
Converging effects of cannabis and psychosis on the dopamine system: A longitudinal neuromelanin-sensitive MRI study in cannabis use disorder and first episode schizophrenia. |
| 早期生活中接触多氯联苯的认知影响：涉及大脑多巴胺系统的性别特异性行为、激素和神经分子机制。 |
Hilz, E. N. |
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N/A |
Cognitive effects of early life exposure to PCBs: Sex-specific behavioral, hormonal and neuromolecular mechanisms involving the brain dopamine system. |
| 实践重塑了任务特化表征的几何结构与动态特性 |
Kikumoto, A. |
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N/A |
Practice Reshapes the Geometry and Dynamics of Task-tailored Representations |
| 海马相位依赖性刺激：一种计算建模方法 |
Lee, H.-P. |
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N/A |
Phase-Dependent Stimulation of the Hippocampus: A Computational Modeling Approach |
| 低温电子显微镜下的磷脂酶Cϵ结构揭示了N端结构域及其在活性中的作用 |
Samassekou, K. |
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N/A |
Cryo-EM Structure of Phospholipase Cϵ Defines N-terminal Domains and their Roles in Activity |
| 人类大脑中的注意力信息传递 |
Boroujeni, K. B. |
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N/A |
Attentional Information Routing in The Human Brain |
| 脑干回路控制小鼠类似咳嗽的气道防御行为 |
Xu, X. |
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N/A |
A brainstem circuit controls cough-like airway defensive behaviors in mice |
| 人类气道上皮细胞的单细胞分析揭示了细胞类型特异性对曲霉菌和球孢子菌的反应 |
Harding, A. T. |
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N/A |
Single-cell analysis of human airway epithelium identifies cell type-specific responses to Aspergillus and Coccidioides |
| 一种新型快速宿主细胞进入途径决定金黄色葡萄球菌的胞内命运 |
Rühling, M. |
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N/A |
A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus |
| 小胶质细胞特异性NF-κB信号传导是朊病毒诱导的胶质炎症和神经元损失的关键调节因子。 |
Hay, A. J. D. |
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N/A |
Microglia-specific NF-κB signaling is a critical regulator of prion-induced glial inflammation and neuronal loss |
| 评估咸海残留湖泊系统：盐度波动对浮游植物群落的影响 |
Malashenkov, D. V. |
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N/A |
Assessing Aral Sea residual lake system: impact of fluctuating salinity on phytoplankton communities |
| 逃离药物偏见陷阱：利用去偏设计提升药物-靶点相互作用预测的可解释性与泛化能力 |
Zhang, P.-D. |
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N/A |
Escaping the drug-bias trap: using debiasing design to improve interpretability and generalization of drug-target interaction prediction |
| TopBP1生物分子凝聚物：晚期结直肠癌的新治疗靶点。 |
Morano, L. |
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N/A |
TopBP1 biomolecular condensates: a new therapeutic target in advanced-stage colorectal cancer. |
| MITF在胃肠道间质瘤中的靶点：对自噬和细胞外囊泡分泌的启示 |
Proano-Perez, E. |
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N/A |
MITF Targets in Gastrointestinal Stromal Tumors: Implication in Autophagy and Extracellular Vesicle Secretion |
| 新型藻蓝蛋白体连接蛋白ApcI调控Synechocystis sp. PCC 6803的高光适应 |
Espinoza-Corral, R. |
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N/A |
The new phycobilisome linker protein ApcI regulates high light adaptation in Synechocystis sp. PCC 6803 |
| 一种针对本科研究生的ChatGPT辅助阅读协议，用于参与生物物理学文献 |
Sambar, M. |
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N/A |
A ChatGPT Assisted Reading Protocol for Undergraduate Research Students Engaging with Biophysics Literature |
| 识别生长分化因子-15作为代谢功能障碍相关脂肪性肝炎的早期预测生物标志物：一项基于英国生物银行蛋白质组数据的嵌套病例对照研究 |
Wang, H. |
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N/A |
Identification of Growth Differentiation Factor-15 as An Early Predictive Biomarker for Metabolic Dysfunction-Associated Steatohepatitis: A Nested Case-control Study of UK Biobank Proteomic Data |
| 评估从黄芩提取物中分离出的反式肉桂酸在体内实验中的降血糖活性 |
Fedorova, A. M. |
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N/A |
Assessment of the hypoglycemic activity of trans-cinnamic acid isolated from the extract of hairy rots Scutellaria baicalensis in in vivo experiments |
| 对黑尿酸症的解剖学研究：对软骨和骨中褐黄病的全新见解 |
Hughes, J. H. |
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N/A |
An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone |
| 共转录RNA加工促进合子基因激活 |
Xu, J. |
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N/A |
Co-transcriptional RNA processing boosts zygotic gene activation |
| 免疫样糖链感知与横向获取的糖链加工在微生物共生中协同调控宿主控制 |
Jenkins, B. H. |
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N/A |
Immune-like glycan-sensing and horizontally-acquired glycan-processing orchestrate host control in a microbial endosymbiosis |
| 在Heliconius蝴蝶中特定模态的记忆增强 |
Hodge, E. |
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N/A |
Modality specific memory enhancement in Heliconius butterflies |
| Megabouts：一种用于斑马鱼运动分析的灵活管道 |
Jouary, A. |
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N/A |
Megabouts: a flexible pipeline for zebrafish locomotion analysis |
| 睡眠-觉醒状态在老鼠大脑的情感调节区域中被编码 |
Walder-Christensen, K. |
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N/A |
Sleep-wake states are encoded across emotion-regulation regions of the mouse brain |
| 评估和比较非周期性神经活动的测量方法 |
Donoghue, T. |
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N/A |
Evaluating and Comparing Measures of Aperiodic Neural Activity |
| 利用跨试验和行为会话的相关性来改进神经解码 |
Zhang, Y. |
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N/A |
Exploiting correlations across trials and behavioral sessions to improve neural decoding |
| 灵长类灵巧手部运动的脊髓和皮质前运动控制 |
Takei, T. |
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N/A |
Spinal and cortical premotor control of primate dexterous hand movements |
| 多路复用推断的尖峰计数分析（SCAMPI） |
Chen, Y. |
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N/A |
Spike Count Analysis for MultiPlexing Inference (SCAMPI) |
| 果蝇味觉回路的连接组分析 |
Walker, S. R. |
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N/A |
Connectomic analysis of taste circuits in Drosophila |
| 不同类型急性运动对皮质醇水平和认知功能影响的比较研究 |
Shao, Z. |
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N/A |
Comparative study on the effects of different types of acute exercise on cortisol levels and cognitive functions |
| 联会复合体在减数分裂期间保护双Holliday连接体 |
Tang, S. M. |
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N/A |
Synaptonemal complex protects double-Holliday junctions during meiosis |
| 应激颗粒的形成使癌细胞能够在无锚定条件下生存。 |
Yang, S. |
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N/A |
Stress granule formation enables anchorage-independence survival in cancer cells |
| 从头设计用于GPCR研究的融合蛋白工具 |
Gao, K. |
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N/A |
De novo Design of A Fusion Protein Tool for GPCR Research |
| 脂质囊泡中膜弯曲与拉伸的耦合 |
Wennerström, H. |
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N/A |
On the coupling between membrane bending and stretching in lipid vesicles |
| 条件定位药理学以时空精度操控细胞周期 |
Deng, C. |
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N/A |
Conditional Localization Pharmacology Manipulates the Cell Cycle with Spatiotemporal Precision |
| PIP5K-Ras双稳态启动质膜对称性破坏，以调控细胞极性和迁移 |
Deng, Y. |
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N/A |
PIP5K-Ras bistability initiates plasma membrane symmetry breaking to regulate cell polarity and migration |
| TAT-1是一种磷脂酰丝氨酸翻转酶，影响蜕皮过程并调控秀丽隐杆线虫表皮中的膜转运。 |
Milne, S. M. |
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N/A |
TAT-1, a phosphatidylserine flippase, affects molting and regulates membrane trafficking in the epidermis of C. elegans |
| 变异进化图：我们能否推断SARS-CoV-2变种的演变过程？ |
Das, B. |
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N/A |
Variant Evolution Graph: Can We Infer How SARS-CoV-2 Variants are Evolving? |
| 小乙型肝炎表面抗原的结构揭示了二聚体形成的机制 |
He, X. |
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N/A |
Structure of small HBV surface antigen reveals mechanism of dimer formation |
| 部分修复导致尿路梗阻逆转后，乳头结构和功能出现永久性缺陷。 |
Vanichapol, T. |
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N/A |
Partial repair causes permanent defects in papillary structure and function after reversal of urinary obstruction |
| 通过在酿酒酵母中的异源表达解码蓝细菌MysDs在类海藻氨基酸生物合成中的特异性 |
Zheng, X. |
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N/A |
Decoding Specificity of Cyanobacterial MysDs in Mycosporine-Like Amino Acid Biosynthesis through Heterologous Expression in Saccharomyces cerevisiae |
| 光触发的蛋白酶介导的合成细胞中肌动蛋白结合货物的释放 |
Akter, M. |
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N/A |
Light-triggered protease-mediated release of actin-bound cargo from synthetic cells |
| 肠道蠕虫通过使DC2向调节性表型发展，以对抗抗蠕虫免疫反应。 |
Andrusaite, A. T. |
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N/A |
Intestinal helminth skews DC2 development towards regulatory phenotype to counter the anti-helminth immune response. |
| 莱姆病病原体中RpoS与BosR之间的正反馈调节 |
Raghunandanan, S. |
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N/A |
Positive feedback regulation between RpoS and BosR in the Lyme disease pathogen |
| HIV-1融合肽在CD4诱导的包膜开放过程中的构象轨迹 |
Thakur, B. |
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N/A |
Conformational trajectory of the HIV-1 fusion peptide during CD4-induced envelope opening |
| 两种与侵食松树的树皮甲虫相关的新物种Graphium（Microascales，子囊菌门）在中国被发现 |
Li, J. |
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N/A |
Two new species of Graphium (Microascales, Ascomycota) associated with pine-infesting bark beetles in China |
| 双歧杆菌青春双歧杆菌CCDM 368的多糖BAP1通过抑制小鼠Th2免疫减轻卵清蛋白诱导的过敏反应 |
Pacyga-Prus, K. |
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N/A |
Polysaccharide BAP1 of Bifidobacterium adolescentis CCDM 368 attenuates ovalbumin-induced allergy through inhibition of Th2 immunity in mice |
| 体外和体内HIV-1潜伏逆转通过Mukungulu，一种激活蛋白激酶C的非洲药用植物提取物 |
Richard, K. |
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N/A |
Ex vivo and in vivo HIV-1 latency reversal by Mukungulu, a protein kinase C-activating African medicinal plant extract |
| 基因密码扩展揭示了活细胞中位点特异性的乳酸化，重塑了蛋白质功能 |
Shao, C. |
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N/A |
Genetic code expansion reveals site-specific lactylation in living cells reshapes protein function |
| 细菌生长温度作为一种水平获得的聚基因性状 |
Farrell, A. A. |
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N/A |
Bacterial growth temperature as a horizontally acquired polygenic trait |
| Tenascin C 缺失损害了肩袖修复后的肌腱愈合和功能恢复 |
TASHJIAN, R. |
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N/A |
Tenascin C Deletion Impairs Tendon Healing and Functional Recovery After Rotator Cuff Repair |
| 全面的蛋白质基因组学和空间分析：转移性黑色素瘤对免疫检查点阻断疗法的先天性和获得性抗性的研究 |
wei, s. |
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N/A |
A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies |
| H2B单泛素化在同源重组修复过程中D-loop代谢中的多方面作用 |
Hung, S.-H. |
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N/A |
Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair |
| Ripply3 过量使用通过在唐氏综合症模型中下调Tbx1，导致中面部缩短。 |
Ahumada Saavedra, J. T. |
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N/A |
Ripply3 overdosage induces mid-face shortening through Tbx1 downregulation in Down syndrome models. |
| 同源多倍体杂交揭示八倍体草莓的起源 |
Fan, Z. |
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N/A |
Homoploid Hybridization Resolves the Origin of Octoploid Strawberries |
| 发现并功能分析导致ROSAH综合征的新型ALPK1变异体 |
Snelling, T. |
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N/A |
Discovery and functional analysis of a novel ALPK1 variant causing ROSAH syndrome |
| NuRD染色质重塑对于修复秀丽隐杆线虫生殖系中的外源性DSB是必需的。 |
Ananthaswamy, D. |
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N/A |
NuRD chromatin remodeling is required to repair exogenous DSBs in the Caenorhabditis elegans germline |
| 酵母中携带缺失的线粒体DNA的遗传偏倚：拷贝数与细胞内选择的作用 |
Kashko, N. D. |
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N/A |
Inheritance bias of deletion-harbouring mtDNA in yeast: the role of copy number and intracellular selection |
| 设计基于细胞的正交泛素转移级联系统以分析RBR E3 Parkin的底物 |
Fang, S. |
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N/A |
Engineering a Cell-Based Orthogonal Ubiquitin Transfer Cascade for Profiling the Substrates of RBR E3 Parkin |
| 通过3D生物打印组织特异性高细胞密度生物墨水进行工程化组织的生物制造 |
Jeon, O. |
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N/A |
Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks |
| 利用无细胞人羊膜进行小血管移植物的生物制造：一项在猪模型中的概念验证研究 |
Aung, O. |
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N/A |
Biofabrication of Small Vascular Graft with Acellular Human Amniotic Membrane: A Proof-of-Concept Study in Pig |
| 更新的AL-Base显示，在AL淀粉样变性中，免疫球蛋白轻链可变基因存在等级富集。 |
Morgan, G. J. |
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N/A |
An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis |
| U2AF1 S34F通过与KRAS突变协同作用并改变对环境压力的反应，增强了肺细胞的肿瘤发生潜能。 |
Liang, C. E. |
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N/A |
U2AF1 S34F enhances tumorigenic potential of lung cells by exhibiting synergy with KRAS mutation and altering response to environmental stress |
| 揭示CRBN分子胶水在化学蛋白质组学中的隐藏相互作用网络 |
Baek, K. |
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N/A |
Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics |
| 番茄半胱氨酸蛋白酶抑制剂SlCYS8作为马铃薯干旱耐受性和块茎产量的触发因子 |
Dorval, M. |
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N/A |
Tomato cystatin SlCYS8 as a trigger of drought tolerance and tuber yield in potato |
| 在没有联网污水处理设施的地区，对土壤传播的蠕虫和其他肠道病原体进行环境监测。 |
Siko, J. E. E. |
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N/A |
Environmental surveillance of soil-transmitted helminths and other enteric pathogens in settings without networked wastewater infrastructure |
| SMARCAD1调控与癌症突变热点相关的活性复制叉处的R-环 |
Uruci, S. |
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N/A |
SMARCAD1 Regulates R-Loops at Active Replication Forks Linked to Cancer Mutation Hotspots |