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BioRxiv 2024-09-17 Papers

标题 作者 PDF链接 代码仓库 Title
先前的脑电图标记了跨试验的专注和心智游移心理状态 Nakatani, C. PDF N/A Prior EEG marks focused and mind-wandering mental states across trials
抑制ABCB7通过触发铁死亡增强顺铂在儿童3型髓母细胞瘤中的反应 Kanchan, R. K. PDF N/A Repressing ABCB7 Potentiates Cisplatin Response in Pediatric Group 3 Medulloblastoma by Triggering Ferroptosis
灵长类动物主要组织相容性复合体中的古老跨物种多态性 Fortier, A. L. PDF N/A Ancient Trans-Species Polymorphism at the Major Histocompatibility Complex in Primates
一种军团菌肺炎杆菌效应蛋白阻碍宿主基因沉默以促进毒力 Toinon, J. PDF N/A A Legionella pneumophila effector impedes host gene silencing to promote virulence
基于细胞外基质的一个简单建模框架 Metzcar, J. PDF N/A A simple framework for agent-based modeling with extracellular matrix
通过深度挖掘宏基因组基序来设计工程噬菌体 Huss, P. PDF N/A Engineering bacteriophages through deep mining of metagenomic motifs
在生态学中追求新奇 Ottaviani, G. PDF N/A On the quest for novelty in ecology
撤回:靶心与标准注视十字对眼球运动和从脑电图分类自然图像的影响 Häberle, G. PDF N/A WITHDRAWN: The influence of the bullseye versus standard fixation cross on eye movements and classifying natural images from EEG
天冬酰胺的供应调控B细胞的体内平衡 Yazicioglu, Y. F. PDF N/A Asparagine availability controls B cell homeostasis
拓扑异构酶3β在减轻细胞应激中的RNA靶点和功能 Teimuri, S. PDF N/A RNA Targets and Function of Topoisomerase 3β in Reducing Cellular Stress
利用基于HHpred的方法对SARS-CoV-2蛋白进行重新注释,为更深入理解这种病毒开辟了新的途径。 Brezellec, P. PDF N/A Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus
筛选人类可药物基因组确定ABHD17B为肝星状细胞中的抗纤维化靶点 Li, W. PDF N/A Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
通过缝隙连接的细胞类型特异性核苷酸共享影响对复制应激的敏感性 Boumard, B. PDF N/A Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress
与认知控制相关的大脑活动的寿命轨迹 Yang, G. PDF N/A The Lifespan Trajectories of Brain Activities Related to Cognitive Control
CNTD1在女性减数分裂的I期进展和交叉点的指定中起着关键作用,对于建立卵巢储备至关重要。 Wood, A. PDF N/A CNTD1 plays crucial roles in prophase I progression and crossover designation during female meiosis and is critical for establishing the ovarian reserve
神经生理学证据表明,感觉预测误差驱动了言语感觉运动适应。 Kim, K. S. PDF N/A Neurophysiological evidence of sensory prediction errors driving speech sensorimotor adaptation
携带包膜的内源性逆转录病毒在后生动物中的前寒武纪起源 Chary, S. PDF N/A Pre-Cambrian origin of envelope-carrying endogenous retroviruses in metazoans
前额叶皮层中不同的奖励线索表征导致了青少年和成年人在奖励动机上的差异 Manzano Nieves, G. PDF N/A Divergent reward cue representations in prefrontal cortex underlie differences in reward motivation between adolescents and adults
脊髓V1抑制性中间神经元簇在出生日期、对运动神经元的投射以及异质性方面存在差异。 Worthy, A. E. PDF N/A Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons and heterogeneity
金黄色葡萄球菌通过强大的丙氨酸消旋酶活性,抵御有机酸阴离子介导的肽聚糖交联抑制作用。 Panda, S. PDF N/A Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity
任务无关的阶段,而非对比度变化,在视觉感知学习中解锁了泛化 Akkoyunlu, B. PDF N/A Task-irrelevant phase but not contrast variability unlocks generalization in visual perceptual learning
从分子量分布的矩差推断代谢速率 Tuobang, L. PDF N/A Infer metabolic velocities from moment differences of molecular weight distributions
HairSplitter:从长且有噪声的读取片段中组装单体型 Faure, R. PDF N/A HairSplitter: haplotype assembly from long, noisy reads
在感知和工作记忆内容之间转移注意力的神经动力学 Gresch, D. PDF N/A Neural dynamics of shifting attention between perception and working-memory contents
脑皮质神经元对脑震荡的转录反应揭示了损伤后的不同命运 Alkaslasi, M. R. PDF N/A The transcriptional response of cortical neurons to concussion reveals divergent fates after injury
通过单核苷酸分辨率建模解析转录起始的核心启动子语法 He, A. Y. PDF N/A Dissection of core promoter syntax through single nucleotide resolution modeling of transcription initiation
不同物种对四种细菌病原体易感性的系统发育信号变化 Sun, H. PDF N/A Varying phylogenetic signal in susceptibility to four bacterial pathogens across species of Drosophilidae
二聚体-单体转变定义了一种超耐热肽聚糖水解酶,该酶通过源自溶菌素的抗菌肽引导筛选从细菌蛋白质组中挖掘得到。 Zhang, L. PDF N/A Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening
预测疼痛基因:利用概率分类器和交互网络进行多模态数据整合 Zhao, N. PDF N/A Predicting pain genes: multi-modal data integration using probabilistic classifiers and interaction networks
河口梯度下潮汐湿地土壤有机碳储量及其稳定机制 Neiske, F. PDF N/A Soil organic carbon stocks and stabilization mechanisms in tidal marshes along estuarine gradients
使用独特标记基因集对scRNA-seq数据进行自动细胞注释 Truong, L. PDF N/A Automated cell annotation in scRNA-seq data using unique marker gene sets
单细胞基因表达的综合分析:一种全面的数据库方法 Truong, L. PDF N/A Integrative analysis of single-cell gene expression: A comprehensive database approach
一个用于简化序列分析的进化统计工具包,支持在网页上进行客户端处理 Karagöl, A. PDF N/A An Evolutionary Statistics Toolkit for Simplified Sequence Analysis on Web with Client-Side Processing
在德国监测自由生活的蜜蜂群落:对栖息地偏好、存活率及公民科学可靠性的洞察 Rutschmann, B. PDF N/A Monitoring free-living honeybee colonies in Germany: Insights into habitat preferences, survival rates, and Citizen Science reliability
睡眠-觉醒周期中突触稳态的边界条件 Kinoshita, F. L. PDF N/A Boundary conditions for synaptic homeodynamics during the sleep-wake cycle
haCCA:空间转录组和代谢组的多模块整合。 Shen, X. PDF N/A haCCA: Multi-module Integrating of spatial transcriptomes and metabolomes.
提高行为振荡检测的灵敏度:对Brookshire(2022)AR-替代方法的改进 Harris, A. M. PDF N/A Detecting behavioural oscillations with increased sensitivity: A modification of Brookshire's (2022) AR-surrogate method
SQANTI-reads:一种用于多样本长读长RNA-seq实验中长读长数据质量评估的工具。 Keil, N. PDF N/A SQANTI-reads: a tool for the quality assessment of long read data in multi-sample lrRNA-seq experiments.
训练对实验性发声学习缺乏经验的斑海豹进行发声学习实验 Duengen, D. PDF N/A Training Experimentally Naive Seals for Vocal Learning Experiments
全基因组搜索鉴定可能赋予臭虫(Cimex lectularius)杀虫剂抗性的基因突变 Toga, K. PDF N/A Genome-wide Search for Gene Mutations likely Conferring Insecticide Resistance in the Common Bed Bug, Cimex lectularius
鸭子接种高致病性禽流感疫苗的积极效果,法国2023-24年 Guinat, C. PDF N/A Promising effects of duck vaccination against highly pathogenic avian influenza, France 2023-24
评估生理指标在利用对比问题测试(CQT)检测欺骗中的应用 Rashid, A. M. S. PDF N/A Evaluating Physiological Indicators in Detecting Deception using the Comparison Question Test (CQT)
质子结合的变构调节使囊泡谷氨酸转运体具有Cl-激活和谷氨酸选择性 Borghans, B. PDF N/A Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters
CRISPRoff表观遗传编辑技术:在人类细胞中实现可编程基因沉默,无需DNA断裂 Pattali, R. K. PDF N/A CRISPRoff epigenetic editing for programmable gene silencing in human cells without DNA breaks
欧洲旧石器时代晚期气候变化下的人口反应 Schmidt, I. PDF N/A Demographic responses to climatic changes during the Final Palaeolithic in Europe
参考样本的表观基因组、转录组和蛋白质组特征分析 Nepal, C. PDF N/A Epigenomic, transcriptomic and proteomic characterizations of reference samples
注意力机制和状态空间基因组语言模型中标记化影响的比较 Lindsey, L. M. PDF N/A A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models
SVbyEye:一种用于表征全基因组组装间结构变异的视觉工具 Porubsky, D. PDF N/A SVbyEye: A visual tool to characterize structural variation among whole-genome assemblies
海洋酵母对基于昆布多糖的底物的利用和降解表明它们在微生物循环动力学中具有生态位特异性的作用。 Arslan-Gatz, B. PDF N/A Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics.
连接组蛋白调控多能造血干细胞和祖细胞在髓系与淋巴系分化中的分支 Karatepe, K. PDF N/A Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
朝着解释养殖北京鸭的繁殖差距迈进 Beyts, C. H. PDF N/A Towards explaining the fertility gap in farmed Pekin ducks
全球树冠结构的谱系 Jucker, T. PDF N/A The global spectrum of tree crown architecture
泛癌线粒体DNA修复基因集的遗传分析 Dong, A. PDF N/A Pan-Cancer Genetic Analysis of Mitochondrial DNA Repair Gene Set
脊髓小脑性共济失调2型(SCA2)脑萎缩的模式与分期:来自ENIGMA-共济失调研究的MRI体积测量 Robertson, J. W. PDF N/A The Pattern and Staging of Brain Atrophy in Spinocerebellar Ataxia Type 2 (SCA2): MRI Volumetrics from ENIGMA-Ataxia
蜱虫中一个单一的祖先ANP32位点产生了多种蛋白质变体,这些变体均支持Thogoto病毒聚合酶的功能。 Zhang, Z. PDF N/A A single ancestral ANP32 locus in ticks creates multiple protein variants that all support the Thogoto virus polymerase
高通量优化的基于质粒编辑的内源性蛋白质标记技术,用于蛋白质定位的池化成像 Sanchez, H. M. PDF N/A High-throughput optimized prime editing mediated endogenous protein tagging for pooled imaging of protein localization
使用蛋白质纳米笼在活细胞中定量比较单体StayGold变体 Viola, G. PDF N/A Quantitative Comparison of Monomeric StayGold Variants Using Protein Nanocages in Living Cells
人诱导多能干细胞(iPSC)衍生的脑周细胞在炎症激活方面与原代人脑周细胞表现出差异。 McCullough, S. PDF N/A Human iPSC-derived brain pericytes exhibit differences in inflammatory activation compared to primary human brain pericytes
自噬通过调控嘌呤核苷信号通路,起到抑制肥胖相关纤维化的作用。 Piletic, K. PDF N/A Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling
HP1α驱动的相分离与异染色质损伤修复途径选择 Bohra, D. PDF N/A HP1α-driven Phase Separation and Repair Pathway Choice in Response to Heterochromatin Damage
重新审视肠球菌属黄褐肠球菌及相关物种的分类 Soares de Medeiros Lima, M. M. PDF N/A Revisiting the taxonomy of Enterococcus casseliflavus and related species
青络饮诱导的SIRT1抑制有助于佐剂诱导的关节炎大鼠免疫改善 Zuo, J. PDF N/A Qing-Luo-Yin-induced SIRT1 inhibition contributes to the immune improvement of adjuvant-induced arthritis rats
更新了包含撤稿数据的科学领域标准化引用指标作者数据库 Ioannidis, J. PDF N/A Updated science-wide author databases of standardized citation indicators including retraction data
H3K4me3结合的ALFIN-LIKE蛋白招募SWR1以在基因体内沉积H2A.Z Xu, L. PDF N/A The H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z
通过休眠的进化稳定波动的人口动态 Miller, Z. R. PDF N/A Stabilization of fluctuating population dynamics via the evolution of dormancy
原发性口腔鳞状细胞癌的蛋白质基因组特征揭示了与淋巴结转移相关的细胞外基质重塑和免疫抑制微环境 Liu, Y. PDF N/A Proteogenomic Characterization of Primary Oral Squamous Cell Carcinomas Unveils the Extracellular Matrix Remodeling and Immunosuppressive Microenvironment Linked with Lymph Node Metastasis
一种统一的贝叶斯方法用于转录组关联研究 Khan, A. K. PDF N/A A unified Bayesian approach to transcriptome-wide association study
加速昆虫嗅觉受体配体的发现 Comte, A. PDF N/A Accelerating Ligand Discovery for Insect Odorant Receptors
通过DeepFuseNMF实现空间转录组学数据的可解释高分辨率降维 Tang, J. PDF N/A Interpretable high-resolution dimension reduction of spatial transcriptomics data by DeepFuseNMF
枝角类动物可保障替代急性鱼类毒性测试的生物检测方法的使用:重点关注神经毒性 Schuer, C. PDF N/A Daphnids Can Safeguard the Use of Alternative Bioassays to the Acute Fish Toxicity Test: A Focus on Neurotoxicity
在加拿大引发高发播散性淋球菌感染的分离株中,表型多样性与共享的基因组决定因素 Binepal, G. PDF N/A Phenotypic diversity and shared genomic determinants among isolates causing a large incidence of disseminated gonococcal infections in Canada
子宫肌层中PRICKLE1的缺失导致小鼠生育力下降、子宫肌层结构异常及细胞外基质沉积异常。 Roberts, E. PDF N/A Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice.
在寒冷环境中发育使得鸟类线粒体更容易受到热应激的影响。 Correia, M. PDF N/A Development in the cold renders bird mitochondria more susceptible to heat stress
在计算机探索中,Amubarvimab和Romlusevimab对SARS-COV-2变种的中和机制 Huan, X. PDF N/A In computer explore The neutralization mechanism of Amubarvimab and Romlusevimab against SARS-COV-2 mutants
一种主要真菌病原体在全球收集物中的热适应性 Minana-Posada, S. PDF N/A Thermal adaptation in worldwide collections of a major fungal pathogen
p53通过调节核结构来降低致癌物敏感性和突变潜能 King, D. A. PDF N/A p53 Regulates Nuclear Architecture to Reduce Carcinogen Sensitivity and Mutagenic Potential
针对癌症相关糖基化进行胃肠道和妇科癌症的过继T细胞治疗 Zingg, A. PDF N/A Targeting cancer-associated glycosylation for adoptive T cell therapy of gastro-intestinal and gynecological cancers
抑制谷氨酰胺酶可诱导治疗诱导的衰老黑色素瘤细胞的衰老消解。 Kim, J. PDF N/A Inhibition of glutaminase elicits senolysis in therapy-induced senescent melanoma cells.
在Pristionchus中,发育转录组学揭示了可塑性基因调控网络的逻辑 Reich, S. PDF N/A Developmental transcriptomics in Pristionchus reveals the logic of a plasticity gene regulatory network
纹状体中快速放电中间神经元的功能性后果 Guo, L. PDF N/A Functional consequences of fast-spiking interneurons in striatum
一种结合了树突非线性特性和反向传播动作电位的V1神经模型 Rentzeperis, I. PDF N/A A neural model for V1 that incorporates dendritic nonlinearities and back-propagating action potentials
层流功能定量磁化率成像的可行性 Straub, S. PDF N/A Feasibility of laminar functional quantitative susceptibility mapping
全脑微卒中影响海马记忆回路的稳定性 Heiser, H. PDF N/A Brain-wide microstrokes affect the stability of memory circuits in the hippocampus
使用条件性GeneSwitch驱动器扩展果蝇血细胞会影响幼虫血细胞功能,但不会调节成虫的寿命或感染后的存活率。 Hayman, D. J. PDF N/A Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival from infection
倾斜错觉源于在上下文边界处对神经编码资源的高效重新分配。 Zhang, L.-Q. PDF N/A The tilt illusion arises from an efficient reallocation of neural coding resources at the contextual boundary
通过眶额皮层自上而下的输入对感觉反应进行预测性过滤 Tsukano, H. PDF N/A Predictive filtering of sensory response via orbitofrontal top-down input
通过解剖和显微计算机断层扫描识别出的人类三叉神经和面神经分支及孔道的变异 Grimes, H. L. PDF N/A Variations in human trigeminal and facial nerve branches and foramina identified by dissection and microcomputed tomography
海马体中人口活动的稀疏性在三突触回路和背腹轴上是任务不变的。 Lee, J. Q. PDF N/A Sparsity of population activity in the hippocampus is task-invariant across the tri-synaptic circuit and dorsal-ventral axis
从前馈到反馈节奏的表征转变,标志着自然视觉中现象学整合的指标。 Chen, L. PDF N/A Representational shifts from feedforward to feedback rhythms index phenomenological integration in natural vision
单极刷状细胞接收到的真实苔藓纤维输入模式,能够引发一系列时间响应,这些响应由不同谷氨酸受体介导的成分组成。 Huson, V. PDF N/A Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors
行为控制的神经递质基础 Ballard, I. C. PDF N/A A dopaminergic basis of behavioral control
皮质连接支持运动同步,以响应前额叶-颞叶网络中的听觉和视觉节奏。 Lu, Y. PDF N/A Cortical connectivity supports motoric synchronization to both auditory and visual rhythms in a frontal-temporal network
清醒大鼠内脏操作的神经影像学模型 Cramer, S. R. PDF N/A Neuroimaging model of visceral manipulation in awake rat
胎儿期暴露于四氢大麻酚(THC)后,急性应激的性别特异性适应不良反应受多巴胺介导。 Serra, V. PDF N/A Sex-specific maladaptive responses to acute stress upon in utero THC exposure are mediated by dopamine
基于MRI的阿尔茨海默病分类的可解释AI模型比较 Chattopadhyay, T. PDF N/A Comparison of Explainable AI Models for MRI-based Alzheimer's Disease Classification
背侧中缝核中的GABA能神经元调节小鼠的社会等级 Fang, G. PDF N/A GABAergic neurons in the dorsal raphe nucleus regulate social hierarchy in mice
杏仁核刺激通过前扣带皮层中非典型PKC的持续激活,将短期记忆转化为远程记忆。 Almaguer-Melian, W. PDF N/A Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical PKC in the anterior cingulate cortex
尽管关键标记基因发生了显著变化,颗粒性后海马皮质的独特转录组细胞类型在鼠和鼠之间得以保留 Brooks, I. A. PDF N/A Unique Transcriptomic Cell Types of the Granular Retrosplenial Cortex are Preserved Across Mice and Rats Despite Dramatic Changes in Key Marker Genes
星形胶质细胞糖皮质激素受体介导应激后性特异性活动变化 Depaauw-Holt, L. PDF N/A Astrocyte glucocorticoid receptors mediate sex-specific changes in activity following stress
高分辨率活体运动学追踪与可注射荧光纳米颗粒 Ulutas, E. Z. PDF N/A High-resolution in vivo kinematic tracking with injectable fluorescent nanoparticles
在小鼠齿状回中,5-HT7受体的激活选择性地增强了GABA能抑制作用,这种抑制作用针对的是门区的苔藓细胞,而不会影响穿通路径突触的可塑性。 Siwiec, M. PDF N/A Activation of 5-HT7 receptors in the mouse dentate gyrus selectively enhances GABAergic inhibition of hilar mossy cells without affecting plasticity at the perforant path synapse
神经元中内源性大麻素过多对认知功能有害。 Zhu, D. PDF N/A Overabundant endocannabinoids in neurons are detrimental to cognitive function
Notch/无毛通路对原肠胚形成前sog转录爆发的调控 Fenelon, K. D. PDF N/A Notch/Hairless Pathway Modulation of sog Transcriptional Bursting in Prelude to Gastrulation
单细胞多组学、空间转录组学和系统扰动揭示神经嵴命运决定的电路 Hu, Z. PDF N/A Single-cell multi-omics, spatial transcriptomics and systematic perturbation decode circuitry of neural crest fate decisions
肉类转移遵循几内亚狒狒多层次社会中的社会关系,但与雄性繁殖成功无关。 O'Hearn, W. J. PDF N/A Meat transfers follow social ties in the multi-level society of Guinea baboons but are not related to male reproductive success
跳蛛不会被周边漂移错觉所迷惑 De Agro, M. PDF N/A Jumping spiders are not fooled by the peripheral drift illusion
温暖水域中猎物显著性的增强缓解了浊度对捕食者的视觉限制 Zanghi, C. PDF N/A Enhanced conspicuousness of prey in warmer water mitigates the visual constraint of turbidity for predators
注意缺陷多动障碍儿童和青少年的大脑边缘系统白质:一项纵向扩散磁共振成像分析 Connaughton, M. PDF N/A Limbic System White Matter in Children and Adolescents with ADHD: A Longitudinal Diffusion MRI Analysis
阿尔茨海默病的病理学破坏了在小鼠进行风险觅食决策期间,灵活的位置细胞编码和海马-前额叶神经动力学。 Kim, E. J. PDF N/A Alzheimer's pathology disrupts flexible place cell coding and hippocampal-prefrontal neural dynamics during risky foraging decisions in mice
皮层状态对早期视觉皮层反应变异性的贡献:一种系统识别方法 Sooriyaarachchi, J. PDF N/A Cortical state contributions to response variability in the early visual cortex: A system identification approach
面部表情与颜色在调节EPR P3中的相互作用 Hasegawa, Y. PDF N/A Interaction between facial expression and color in modulating EPR P3
MPXV以I型干扰素敏感的方式感染人外周血单核细胞 Bosquillon de Jarcy, L. PDF N/A MPXV Infects Human PBMCs in a Type I Interferon-Sensitive Manner
SARS-Cov-2 N蛋白的亲和标签免费纯化及其与ssDNA复合物的晶体结构 Maiti, A. PDF N/A Affinity tag free purification of SARS-Cov-2 N protein and its crystal structure in complex with ssDNA
PangeBlocks:通过最大块实现泛基因组图的自定义构建 Bonizzoni, P. PDF N/A PangeBlocks: customized construction of pangenome graphs via maximal blocks
基于相分离合成细胞器的代谢物响应转录调控 Jerez-Longres, C. PDF N/A Metabolite-responsive Control of Transcription by Phase Separation-based Synthetic Organelles
一种用于编程干细胞内源基因多步骤激活的模块化系统 Puppala, A. K. PDF N/A A modular system for programming multistep activation of endogenous genes in stem cells
在聚球藻PCC 7002中实现高效转化与基因表达 Hren, A. P. PDF N/A High-efficiency transformation and gene expression in Picosynechococcus sp. PCC 7002
合成细胞模型中膜相分离与细菌分裂蛋白动态之间的相互依赖关系 Kanwa, N. PDF N/A Mutual dependence between membrane phase separation and bacterial division protein dynamics in synthetic cell models
炎症和转移性癌症中肺淋巴管的原位成像 Cleary, S. J. PDF N/A Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer
一个涵盖5000年的古代人类口腔微生物组研究的广泛考古牙结石数据集 Standeven, F. J. PDF N/A An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research
斯里兰卡人感染的细螺旋体博氏菌株的基因组分析揭示了PF07598基因家族谱系的扩展,其整体基因组缩减程度低于牛感染的菌株。 Senavirathna, I. PDF N/A Genomic Analysis of Human-infecting Leptospira borgpetersenii isolates in Sri Lanka expanded PF07598 gene family repertoire, less overall genome reduction than bovine isolates
一种慢性小鼠肺部鲍曼不动杆菌感染模型,可用于研究晚期毒力因子、长期抗生素治疗以及多菌种感染。 Jackson-Litteken, C. D. D. PDF N/A A chronic murine model of pulmonary Acinetobacter baumannii infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections
人类肠道细菌对PFAS的广泛积累 Lindell, A. E. PDF N/A Extensive PFAS accumulation by human gut bacteria
艰难梭菌的ruberythrin基因座能有效解毒活性氧物质。 Knop, R. PDF N/A A rubrerythrin locus of Clostridioides difficile efficiently detoxifies reactive oxygen species
标题:坦桑尼亚北部野生动物保护区附近牛群非洲动物锥虫病治疗失败原因的纵向观察(单队列)研究 Richards, S. PDF N/A Title Longitudinal Observational (single cohort) Study on the Causes of Trypanocide Failure in cases of African Animal Trypanosomosis in Cattle Near Wildlife Protected Areas of Northern Tanzania
RNA聚合酶II在活性启动子上协调组蛋白去乙酰化 Hoffman, J. A. PDF N/A RNA Polymerase II coordinates histone deacetylation at active promoters
Transportin-1介导的PPARg核运输机制的结构解析 TOMA-FUKAI, S. PDF N/A Structural insight into the nuclear transportation mechanism of PPARg by Transportin-1
针对FUS-ALS聚集,使用蛋白酶体抑制剂进行靶向治疗 Younis, A. PDF N/A Targeting FUS-ALS aggregation with Proteasome Inhibitors
通过激活mTOR/TFEB增强溶酶体功能可减少早期年龄相关性黄斑变性中的脂褐素样颗粒 Falcao, A. S. PDF N/A Enhancing lysosome function via mTOR/TFEB activation reduces lipofuscin-like granules in early Age-related Macular Degeneration
pytom-match-pick:模板匹配中用于自动化分类的tophat-transform约束 Chaillet, M. L. PDF N/A pytom-match-pick: a tophat-transform constraint for automated classification in template matching
评估埃博拉病毒在刚果民主共和国赤道省的传播:一项关于野生动物与人类互动的一体化健康调查 van Vredendaal, R. PDF N/A Assessing Ebola Virus Circulation in the Tshuapa Province (Democratic Republic of the Congo): A One Health Investigation of Wildlife and Human Interactions
将种内变异整合到种群动态中,揭示了相互作用的物种如何在互利共生群落中持续存在 Arroyo-Correa, B. PDF N/A Integrating intraspecific variation into population dynamics reveals how interacting species persist in mutualistic communities
气候适应性有助于全球入侵 Gamba, D. PDF N/A Local adaptation to climate facilitates a global invasion
过去5000年葡萄牙的遗传史 Roca-Rada, X. PDF N/A The genetic history of Portugal over the past 5,000 years
利用直接胶原纤维模型捕捉巩膜各向异性。将微观结构与宏观力学特性联系起来。 Ji, F. PDF N/A Capturing sclera anisotropy using direct collagen fiber models. Linking microstructure to macroscopic mechanical properties.
使用可调细胞外基质水凝胶系统精准修复特定区域的半月板损伤 Lee, S.-H. PDF N/A Precision Repair of Zone-Specific Meniscal Injuries Using a Tunable Extracellular Matrix-Based Hydrogel System
CRAK-Velo:染色质可及性动力学整合提升RNA速度估算 El Kazwini, N. PDF N/A CRAK-Velo: Chromatin Accessibility Kinetics integration improves RNA Velocity estimation
短读长纳米孔测序的精确碱基识别 Wang, Z. PDF N/A The Precise Basecalling of Short-Read Nanopore Sequencing
尽管存档切片存在噪声,机器学习仍能收敛于黑色素细胞形态 Tada, M. PDF N/A Machine-learning convergent melanocytic morphology despite noisy archival slides
连接小管中的通路流动引起传入小动脉的血管舒张。 Wang, H. PDF N/A Luminal Flow in the Connecting Tubule induces Afferent Arteriole Vasodilation
利用分裂mVenus方法在植物系统中实施Ribo-BiFC技术的实现 Raabe, K. PDF N/A Implementation of Ribo-BiFC method to plant systems using a split mVenus approach
在鼠伤寒沙门氏菌中可逆地切除wzy位点可能有助于在噬菌体捕食后恢复 Charity, O. J. PDF N/A Reversible excision of the wzy locus in Salmonella Typhimurium may aid recovery following phage predation
利用工程化的连接选择性去泛素化酶解码多泛素化对KV7.1功能表达的调控 Shanmugam, S. K. PDF N/A Decoding polyubiquitin regulation of KV7. 1 functional expression with engineered linkage-selective deubiquitinases
利用高分辨率基因表达谱揭示被子植物中全基因组加倍后的保守进化响应 Leal, J. L. PDF N/A Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling
人类凝聚蛋白亚基的分子动力学模拟识别出DNA结合位点及其在DNA环挤出中的潜在作用 Gu, C. PDF N/A Molecular dynamics simulations of human cohesin subunits identify DNA binding sites and their potential roles in DNA loop extrusion