| PPARγ域间通讯的结构基础 |
Mosure, S. A. |
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N/A |
Structural basis of interdomain communication in PPARγ |
| 灵长类前额叶皮层中对扫视运动的预期性和回顾性表征 |
Calangiu, I. |
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N/A |
Prospective and retrospective representations of saccadic movements in primate prefrontal cortex |
| 用于分析和估计随机生化反应网络的滤波有限状态投影方法。 |
D'Ambrosio, E. S. |
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N/A |
Filtered finite state projection method for the analysis and estimation of stochastic biochemical reaction networks. |
| 膜嵌入的人类T细胞受体-CD3复合物在静息状态和配体结合状态下的结构 |
Notti, R. Q. |
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N/A |
The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex |
| UGGT1介导的N-糖基化与不稳定的和错误折叠的糖蛋白的ER相关降解相竞争 |
Ninagawa, S. |
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N/A |
UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins |
| 在不同啮齿动物杂交中，不同的复杂调控表型是导致杂交雄性不育的根源。 |
Hunnicutt, K. E. |
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N/A |
Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses |
| 在人类大脑进化和疾病过程中，KRAB锌指基因和转座子的调控网络发生了变化。 |
Chen, Y.-C. |
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N/A |
Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease |
| 利用信息几何对细胞表型过渡流形进行几何量化 |
Huang, M. |
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N/A |
Geometric Quantification of Cell Phenotype Transition Manifolds with Information Geometry |
| 在蛋白质结构约束下的基因重复功能多样化 |
Guo, K. |
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N/A |
Functional Diversification of Gene Duplicates under the Constraint of Protein Structure |
| 比较单细胞分析揭示了胎儿-母体界面细胞类型和细胞信号创新的复杂模式 |
Stadtmauer, D. J. |
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N/A |
Comparative single cell analysis reveals complex patterns of cell type and cell signaling innovations at the fetal-maternal interface |
| 伏隔核内侧壳中的胃泌素释放肽信号调节神经元兴奋性和动机 |
Aisenberg, E. E. |
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N/A |
Gastrin-releasing peptide signaling in the nucleus accumbens medial shell regulates neuronal excitability and motivation |
| 药物诱导的p53激活限制了胰腺癌的启动 |
Twardowski, J. J. |
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N/A |
Drug-Induced p53 Activation Limits Pancreatic Cancer Initiation |
| 加拉帕戈斯黄莺在应对交通噪音的行为可塑性方面，因与道路的距离不同而有所差异。 |
Hohl, L. |
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N/A |
Galapagos yellow warblers differ in behavioural plasticity in response to traffic noise depending on proximity to road. |
| 开发辣椒素衍生物作为抑制素配体，以调节癌细胞中的Aurora激酶A/PHB2相互作用 |
Djehal, A. |
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N/A |
Development of capsaicin derivatives as prohibitin ligands to modulate the Aurora kinase A/PHB2 interaction in cancer cells |
| 单等位基因表观遗传调控布氏锥虫中RNA聚合酶II多顺反子转录起始的双向沉默。 |
Kieft, R. |
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N/A |
Mono-allelic epigenetic regulation of bi-directional silencing of RNA Polymerase II polycistronic transcription initiation in Trypanosoma brucei. |
| 单核RNA测序揭示了纹状体小胶质细胞中急性应激和慢性运动的持久特征 |
Connolly, M. G. |
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N/A |
Single-nucleus RNA sequencing reveals enduring signatures of acute stress and chronic exercise in striatal microglia |
| 从人类多能干细胞可扩展地分化出下丘脑弓状核神经元，适用于代谢和生殖障碍的模型构建 |
Jovanovic, V. M. |
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N/A |
Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders |
| 鲁棒的结合能力和端粒结合蛋白的丧失是端粒重复基序进化的基础 |
Song, H. |
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N/A |
Robust Binding Capability and Loss of Telomere-Binding Proteins Underlying the Evolution of Telomeric Repeat Motifs |
| 一种即时语音合成神经假体 |
Wairagkar, M. |
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N/A |
An instantaneous voice synthesis neuroprosthesis |
| 评估预测哺乳动物皮层细胞类型特异性增强子的方法 |
Johansen, N. J. |
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N/A |
Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex |
| 高通量无监督量化模式在狨猴自然行为中的应用 |
Menegas, W. |
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N/A |
High-throughput unsupervised quantification of patterns in the natural behavior of marmosets |
| 外来入侵物种的灭绝潜力 |
Philippe-Lesaffre, M. |
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N/A |
Extinction potential from invasive alien species |
| 促性腺激素细胞具有双重起源，其中大多数在微青春期期间由垂体干细胞分化而来。 |
Sheridan, D. |
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N/A |
Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. |
| 肌梭为运动序列提供灵活的感觉反馈。 |
Olson, W. P. |
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N/A |
Muscle spindles provide flexible sensory feedback for movement sequences |
| RCoxNet：一种集成随机游走重启与突变及临床数据的癌症生存预测深度学习框架 |
Kumari, S. |
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N/A |
RCoxNet: deep learning framework for enhanced cancer survival prediction integrating random walk with restart with mutation and clinical data |
| metagWGS，一个利用Illumina或PacBio HiFi读取数据进行宏基因组数据分析的综合工作流程 |
Mainguy, J. |
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N/A |
metagWGS, a comprehensive workflow to analyze metagenomic data using Illumina or PacBio HiFi reads |
| 在反思室和VR头戴设备环境中，对比呼吸练习与自然主义刺激对认知、行为和生理反应的影响：随机对照研究 |
Simonian, N. |
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N/A |
Contrasting Cognitive, Behavioral, and Physiological Responses to Breathwork vs. Naturalistic Stimuli in Reflective Chamber and VR Headset Environments: Randomized Control Study |
| 通过ER-Hoxb8条件性永生化巨噬细胞替代小胶质细胞，为深入了解Aicardi-Goutieres综合征的神经病理学提供了新的视角。 |
Nemec, K. M. |
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N/A |
Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology |
| 制造感知的生成模型架构能够实现生物序列的设计和合成，规模达到千万亿级 |
Weinstein, E. N. |
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N/A |
Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale |
| 氧化应激的隔离是必要的，但不足以得出姜黄素对多巴胺能神经的保护作用：来自ALSS果蝇帕金森病模型的见解 |
Phom, L. |
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N/A |
Sequestration of oxidative is necessary but not sufficient enough to conclude dopaminergic neuroprotective efficacy of curcumin: Insights from ALSS Drosophila Parkinson disease model |
| 结构系统发育学的一般替代矩阵。 |
Garg, S. G. |
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N/A |
A general substitution matrix for structural phylogenetics. |
| 使用质粒分析服务进行高效且经济的长时间读取扩增子测序：应用于日本牵牛花中的转座子插入等位基因 |
Nakagawa, S. |
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N/A |
Labor- and cost-effective long-read amplicon sequencing using a plasmid analysis service: Application to transposon-inserted alleles in Japanese morning glory |
| 对CLAP数据的重新分析证实了PRC2是一种RNA结合蛋白。 |
Lee, Y. |
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N/A |
Re-analysis of CLAP data affirms PRC2 as an RNA binding protein |
| 泛基因组启发的语言模型用于隐私保护的合成基因组序列生成 |
Huang, P. |
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N/A |
Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation |
| SoyOD：一个综合的大豆多组学数据库，用于挖掘基因和生物学研究 |
Li, J. |
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N/A |
SoyOD: An Integrated Soybean Multi-omics Database for Mining Genes and Biological Research |
| 功能连接主要由非周期性的耦合，而非振荡性的耦合所主导。 |
Monchy, N. |
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N/A |
Functional connectivity is dominated by aperiodic, rather than oscillatory, coupling |
| InTraSeq：一种揭示新型单细胞生物学和调控机制的多模态分析方法 |
Ariss, M. M. |
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N/A |
InTraSeq: A Multimodal Assay that Uncovers New Single-Cell Biology and Regulatory Mechanisms |
| 磷酸化诱导的SUMO化促进Ulk4在纤毛尖端的凝聚，以转导Hedgehog信号 |
Zhou, M. |
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N/A |
Phosphorylation-induced SUMOylation promotes Ulk4 condensation at ciliary tip to transduce Hedgehog signal |
| 细胞器向内运输推动纺锤体在秀丽隐杆线虫减数分裂期间向外迁移 |
Peraza, A. A. |
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N/A |
Inward transport of organelles drives outward migration of the spindle during C. elegans meiosis |
| 如何构建eDNA定制条形码参考库的最佳实践？以澳大利亚地下动物为例的研究。 |
Guzik, M. |
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N/A |
What are the best practices for curating eDNA custom barcode reference libraries? A case study using Australian subterranean fauna. |
| 对“蛋白质序列景观并不那么简单：关于无参考与基于参考推断”的回应 |
Park, Y. |
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N/A |
Response to "Protein sequence landscapes are not so simple: on reference-free versus reference-based inference" |
| 染色体外DNA与核凝聚物相关联，并通过重组染色质结构来增强致癌转录 |
Taghbalout, A. |
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N/A |
Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription |
| 将全长FLT1表达重定向至其可溶性异构体可促进缺血后血管生成 |
Bundalo, M. |
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N/A |
Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis |
| 用泛扩张显微镜可视化核孔复合体的可塑性 |
Morgan, K. J. |
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N/A |
Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy |
| 二硫键介导的TRAP1四聚化促进了其抗氧化和促肿瘤活性。 |
Faienza, F. |
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N/A |
Disulfide-mediated tetramerization of TRAP1 fosters its antioxidant and pro-neoplastic activities. |
| 通过地理信息学捕捉盐沼地下生物量的时空变化，这是关键的恢复力指标。 |
Runion, K. D. |
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N/A |
Capturing spatiotemporal variation in salt marsh belowground biomass, a key resilience metric, through geoinformatics |
| 不仅仅是果香：十二种番荔枝科植物的花部生物学、香气与光谱反射率 |
Liu, M.-F. |
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N/A |
More than fruity scents: floral biology, scent and spectral reflectance of twelve Annonaceae species |
| 揭示西尼罗病毒传播的温度敏感性：蚊媒病原体性状响应的新型计算方法 |
Heidecke, J. |
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N/A |
Disclosing temperature sensitivity of West Nile virus transmission: novel computational approaches to mosquito-pathogen trait responses |
| AusAMF：澳大利亚丛枝菌根真菌群落数据库 |
Frew, A. |
PDF |
N/A |
AusAMF: database of arbuscular mycorrhizal fungal communities in Australia |
| 宿主异质性对流行病动态的影响取决于宿主传染性是如何确定的。 |
Cohen, J. A. |
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N/A |
Effects of host heterogeneity on epidemiological dynamics are mediated by how host infectiousness is determined |
| 树种多样性降低温带森林病原体损害：一项系统综述与元分析 |
Field, E. |
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N/A |
Tree diversity reduces pathogen damage in temperate forests: a systematic review and meta-analysis |
| 鱼类环境RNA测序通过短期水族箱采样灵敏地捕捉累积应激反应 |
Miyata, K. |
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N/A |
Fish environmental RNA sequencing sensitively captures accumulative stress responses through short-term aquarium sampling |
| 转录后调控IFI16促进在肺动脉高压中观察到的炎症性内皮病理表型 |
Rao, R. J. |
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N/A |
Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension |
| 大麻哈鱼虱（Lepeoptheirus salmonis）在斑点鲽（Cyclopterus lumpus）体内的消化时间与新鲜度、发育阶段及温度相关。 |
Eliasen, K. |
PDF |
N/A |
The digestion time for salmon louse (Lepeoptheirus salmonis) in lumpfish (Cyclopterus lumpus) in relation to freshness, developmental stage, and temperature |
| 全球基因型与环境预测竞赛揭示出，多样化的建模策略能够提供令人满意的玉米产量估算 |
Washburn, J. D. |
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N/A |
Global Genotype by Environment Prediction Competition Reveals That Diverse Modeling Strategies Can Deliver Satisfactory Maize Yield Estimates |
| 两种海蛄虾物种Echinogammarus marinus和Gammarus pulex在夜间光照水平逐渐增加下的行为节律 |
Underwood, C. N. |
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N/A |
Behavioural rhythms of two gammarid species Echinogammarus marinus and Gammarus pulex under increasing levels of light at night |
| 用于低剂量率瘤内放射治疗的掺钇-90金属有机框架（MOFs） |
Qi, X. |
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N/A |
Yttrium-90-doped metal-organic frameworks (MOFs) for low-dose rate intratumoral radiotherapy |
| 通过在玻片上使用Mucinase StcE进行消化，对MUC2糖肽进行糖基位点映射和原位质谱成像 |
Lowery, S. C. |
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N/A |
Glycosite Mapping and in situ Mass Spectrometry Imaging of MUC2 Glycopeptides via On-slide Digestion with Mucinase StcE |
| 在拟南芥中，双酰胺的形成需要与DPH1相互作用的DPH2，以实现对光和氧化应激的抗性。 |
Kraemer, U. |
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N/A |
Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance |
| 新型调节因子Fpr2通过依赖于CCL4的中性粒细胞控制免疫稳态 |
Mei, S. |
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N/A |
Novel regulator Fpr2 controls immune homeostasis via CCL4-dependent neutrophils |
| 单纯疱疹病毒在感染小鼠皮肤后的组装与扩散 |
Richardo, T. |
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N/A |
Herpes Simplex Virus Assembly and Spread in murine skin after infection from the outside |
| 通过3,034个基因组的视角概述酿酒酵母的种群结构 |
Loegler, V. |
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N/A |
Overview of the Saccharomyces cerevisiae population structure through the lens of 3,034 genomes |
| 细菌和酵母表达系统中植物类病毒颗粒形成的研究 |
Balke, I. |
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N/A |
Investigation of plant virus-like particle formation in bacterial and yeast expression systems |
| 中枢突触前末梢通过限制再循环池密度来调节自发突触囊泡胞吐速率 |
Wilson, P. |
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N/A |
Central Presynapses Regulate Spontaneous Synaptic Vesicle Exocytosis Rate by Constraining Recycling Pool Density |
| Cytoophidium复合物与细胞命运产生共鸣 |
Li, Y.-L. |
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N/A |
Cytoophidium complexes resonate with cell fates |
| 通过数学建模理解组织金属蛋白酶抑制剂对慢性伤口调节的作用 |
Dari, S. |
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N/A |
Understanding the regulation of chronic wounds by tissue inhibitors of matrix metalloproteinases through mathematical modelling |
| 关键物种对全球引入的强毒病原体的快速适应 |
Cassin-Sackett, L. |
PDF |
N/A |
Rapid adaptation to a globally introduced virulent pathogen in a keystone species |
| 葡甘露聚糖工程突显了半乳糖基化修饰在微调拟南芥细胞壁中纤维素-葡甘露聚糖相互作用中的作用。 |
Yoshimi, Y. |
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N/A |
Glucomannan engineering highlights the role of galactosyl modification in fine-tuning cellulose-glucomannan interaction in Arabidopsis cell walls |
| 聚集的巨噬细胞通过协调的入侵泡合作消除肿瘤。 |
Dooling, L. J. |
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N/A |
Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia |
| 网络驱动的不可苏拉姆新底物识别，用于靶向蛋白质降解 |
Jarnuczak, A. F. |
PDF |
N/A |
Network-driven identification of indisulam neo-substrates for targeted protein degradation |
| Fusobacterium nucleatum通过三聚自转运粘附素CbpF与免疫细胞结合的结构基础 |
Marongiu, G. L. |
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N/A |
Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF |
| 一种用于生理条件下适冷物种生物学研究的高分辨率显微系统 |
Marty, A.-P. M. |
PDF |
N/A |
A high-resolution microscopy system for biological studies of cold-adapted species under physiological conditions |
| 单分子多重寿命成像与门控单光子相机 |
Ronceray, N. |
PDF |
N/A |
Multiplexed lifetime imaging of single molecules with a gated single-photon camera |
| 聚焦镓离子束的生物体积电子显微镜依赖于在断面形成抗辐射的富镓层。 |
Yang, Z. |
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N/A |
Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face |
| 通过HLA I类分子识别儿童脑瘤细胞表面呈现的天然寨卡病毒肽段 |
Sherwood, M. |
PDF |
N/A |
Identification of natural Zika virus peptides presented on the surface of paediatric brain tumour cells by HLA classI |
| 利用先验生物学知识推断和聚类突变特征的贝叶斯框架。 |
Buscaroli, E. |
PDF |
N/A |
A Bayesian framework to infer and cluster mutational signatures leveraging prior biological knowledge. |
| 急性髓系白血病中的PTPN11突变克隆层次结构 |
Fobare, S. |
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N/A |
PTPN11 Mutation Clonal Hierarchy in Acute Myeloid Leukemia |
| 15q11.2缺失相关神经发育障碍的人类神经元模型中的发育改变和网络连接性变化 |
Habela, C. W. |
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N/A |
Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders |
| O-GlcNAc糖基化水平升高对齿状回中线粒体自噬和小胶质细胞的影响 |
Kramer, J. |
PDF |
N/A |
Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus |
| 小鼠中蛋白质O-GlcNAc糖基化的急性增加导致大脑转录组变化，这与在阿尔茨海默病中观察到的相反。 |
Bell, M. |
PDF |
N/A |
Acute increase of protein O-GlcNAcylation in mice leads to transcriptome changes in the brain opposite to what is observed in Alzheimer Disease |
| Sca-1表达描绘了在稳态和病理条件下的小鼠中性粒细胞的促炎状态。 |
Nahiyera, M. |
PDF |
N/A |
Sca-1 expression depicts pro-inflammatory murine neutrophils under steady state and pathological conditions |
| DNA-PK 调控环二核苷酸相关的一型干扰素反应 |
taffoni, c. |
PDF |
N/A |
DNA-PK controls cyclic dinucleotide-associated type I Interferon responses |
| 一项邻近连接分析筛选出SNAT2作为MARCH1 E3泛素连接酶的新型靶标 |
Balthazard, R. |
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N/A |
A proximity ligation screen identifies SNAT2 as a novel target of the MARCH1 E3 ubiquitin ligase |
| 植物逆转了养分添加对土壤多功能性抗旱性的积极影响 |
Piton, G. |
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N/A |
Plants reverse the positive effect of nutrient addition on the drought resistance of soil multifunctionality |
| 高通量氨基酸水平分析纤溶酶原激活剂抑制剂-1与不同变异蛋白酶相互作用的研究 |
Haynes, L. M. |
PDF |
N/A |
High-throughput amino acid-level characterization of the interactions of plasminogen activator inhibitor-1 with variably divergent proteases |
| 对一种极度濒危软体动物的突变率及其进化后果的直接测量 |
Wooldridge, B. |
PDF |
N/A |
Direct measurement of the mutation rate and its evolutionary consequences in a critically endangered mollusk |
| 酵母基因组数据库：基因组注释的进展、扩展的生化途径以及其他关键增强功能 |
Engel, S. R. |
PDF |
N/A |
Saccharomyces Genome Database: Advances in Genome Annotation, Expanded Biochemical Pathways, and Other Key Enhancements |
| 肝细胞癌的表观基因组分析揭示了异常的顺式调控变化和失调的逆转录转座子，这些变化具有预后潜力。 |
Cheng, C. C. Y. |
PDF |
N/A |
Epigenomic analysis of hepatocellular carcinoma reveals aberrant cis-regulatory changes and dysregulated retrotransposons with prognostic potentials |
| 一种新型高特异性和可溶性蛋白酶，用于精确去除N端纯化标签 |
Shams, R. |
PDF |
N/A |
A new highly specific and soluble protease for precise removal of N-terminal purification tags |
| Palmatine与DNA的主要结合模式 |
Gentile, M. |
PDF |
N/A |
The predominant binding mode of Palmatine to DNA |
| 先天免疫受体NLRX1：胶质母细胞瘤病理生理学的潜在调节因子 |
Meena, D. |
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N/A |
Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology |
| 引发剂对橡树幼苗防御白粉病的特异性机制 |
Sanchez-Lucas, R. |
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N/A |
Elicitor specific mechanisms of defence priming in oak seedlings against powdery mildew |
| 优化小鼠血脑屏障血管的富集，重点聚焦于采集后分析中的网络层次结构 |
Abdelazim, H. |
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N/A |
Optimized Enrichment of Murine Blood-Brain Barrier Vessels with a Critical Focus on Network Hierarchy in Post-Collection Analysis |
| 牛血液树突状细胞和单核细胞亚群中XCR1、CX3CR1、CSF1R和ADGRE1的表达 |
Talker, S. C. |
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Expression of XCR1, CX3CR1, CSF1R and ADGRE1 on subsets of bovine blood dendritic cells and monocytes |
| 极端微生物固定化核苷2'-脱氧核糖基转移酶用于核苷生物催化 |
Hernandez Martinez, S. A. |
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N/A |
Immobilized Nucleoside 2'-Deoxyribosyltransferases from Extremophiles for Nucleoside Biocatalysis |
| 潜在的癌症生物标志物：有丝分裂期DNA损伤检查点基因 |
Agarwal, K. |
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N/A |
Potential Cancer Biomarkers: Mitotic Intra-S DNA Damage Checkpoint Genes |
| scaLR：一个基于低资源深度神经网络的单细胞分析与生物标志物发现平台 |
Jogani, S. |
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N/A |
scaLR: a low-resource deep neural network-based platform for single cell analysis and biomarker discovery |
| 基于花序逆转的日中性大麻（Cannabis sativa L.）微繁殖技术 |
Tabatabaei, D. S. |
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N/A |
Floral Reversion based micropropagation of Day-Neutral Cannabis sativa L. |
| 专业学会支持的生物学教育DEI研究的系统综述：该领域的研究群体、研究方法及分析层次 |
Idlebird, C. |
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N/A |
A systematic review of professional society-backed biology education DEI research: The groups, research methods, and levels of analyses comprising the field |
| 随机獾扑杀试验缺乏主动獾扑杀对牛结核病影响的证据：对Mills等人2024年研究（第一部分与第二部分）的评论 |
Torgerson, P. |
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Randomised Badger Culling Trial lacks evidence for proactive badger culling effect on tuberculosis in cattle: comment on Mills et al. 2024, Parts I & II |
| 血管性认知障碍机制及相互作用的一个以炎症为中心的视角 |
Zeylan, M. E. |
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N/A |
An Inflammation Centered Perspective to the Mechanisms and Interactions Related to Vascular Cognitive Impairment |
| BrainUnit：将物理单位融入高性能AI驱动的科学计算 |
Wang, C. |
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BrainUnit: Integrating Physical Units into High-Performance AI-Driven Scientific Computing |
| 早期精神分裂症中的静息态超连接和低连接：我们应该关注冰山的哪一角？ |
Tomecek, D. |
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Resting-state hyper- and hypo-connectivity in early schizophrenia: which tip of the iceberg should we focus on? |
| 器官特异性交感神经支配定义了内脏功能 |
Wang, T. |
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N/A |
Organ-specific Sympathetic Innervation Defines Visceral Functions |
| 从功能性磁共振成像数据解码参数化抓握力预期 |
Caccialupi, G. |
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N/A |
Decoding Parametric Grip-Force Anticipation from fMRI-Data |
| 特征基因揭示了小鼠和鱼类大脑发育过程中不变的全球空间模式 |
Kerstjens, S. |
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Eigengene reveals invariant global spatial patterns across mouse and fish brain development |
| 增加早期内体适配器APPL1的神经元表达会导致内体和突触功能障碍，伴随胆碱能神经退化。 |
Jiang, Y. |
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N/A |
Increased neuronal expression of the early endosomal adaptor APPL1 leads to endosomal and synaptic dysfunction with cholinergic neurodegeneration |
| 社会结构对和尚鹦鹉发声灵活性的影响 |
Smeele, S. Q. |
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N/A |
The effect of social structure on vocal flexibility in monk parakeets |
| 传入感觉噪声对连续吸引子网络模型中网格状放电和路径整合的双重影响 |
Nagaraj, H. |
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Dichotomous impact of afferent sensory noise on grid-patterned firing and path integration in a continuous attractor network model |
| 哺乳动物视网膜双极细胞：兔视网膜的形态学鉴定与系统分类，并进行比较视角的探讨 |
Famiglietti, E. V. |
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Mammalian Retinal Bipolar Cells: Morphological Identification and Systematic Classification in Rabbit Retina, with a Comparative Perspective |
| 证据表明Dmrta2在小鼠皮层祖细胞中作为Pax6的转录抑制因子，并鉴定出与人类小头畸形相关的关键DNA识别突变 |
Shen, X. |
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Evidence that Dmrta2 acts as a transcriptional repressor of Pax6 in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in human |
| 毛细血管尺度的微血管成像：高频超声定位显微镜在小鼠大脑中的应用 |
Lowerison, M. |
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Capillary-scale Microvessel Imaging with High-frequency Ultrasound Localization Microscopy in Mouse Brain |
| 模式化的无线经颅光遗传学技术能够产生人工感知 |
Wu, M. |
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N/A |
Patterned wireless transcranial optogenetics generates artificial perception |
| 猕猴腹侧顶内皮层的功能连接模式揭示了一种前-后向的特化，类似于人类腹侧顶内皮层区域所描述的特征。 |
Sheng, W.-A. |
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N/A |
The macaque ventral intraparietal functional connectivity patterns reveal an anterio-posterior specialization mirroring that described in human ventral intraparietal area |
| 出生后前六个月大脑网络的空间发展 |
Seraji, M. |
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N/A |
Spatial Development of Brain Networks During The First Six Postnatal Months |
| 活体脑片中模拟缺血通过打开Na+/K+泵来模拟：对扩散性去极化生成的线索。 |
Kim, D. |
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Simulated ischemia in live cerebral slices is mimicked by opening the Na+/K+ pump: clues to the generation of spreading depolarization. |
| T1234：一种针对高分辨率fMRI数据配准错误的畸变匹配结构扫描解决方案 |
Kan, C. |
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T1234: A distortion-matched structural scan solution to misregistration of high resolution fMRI data |
| 探索同步的边缘：慢波侵蚀了行为猴子的静息活动 |
Pazienti, A. |
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Probing the edge of synchronization: Slow waves erode resting activity in behaving monkeys |
| 动脉自旋标记灌注磁共振成像分析用于人类连接组项目生命周期老化与发展研究 |
Kirk, T. F. |
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Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies |
| 神经元脂滴在维持全身能量稳态中发挥着保守且性别偏向的作用。 |
Manceau, R. |
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Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis |
| 僵直性清醒巩固：10赫兹重复视觉刺激增强视觉学习的离线增益 |
Yang, X.-Y. |
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Tetanizing wakeful consolidation: ten-hertz repetitive visual stimulation enhances the offline gain of visual learning |
| 人类多巴胺能神经元携带LRRK2 G2019S突变的细胞内和细胞外蛋白质组特征 |
Knab, F. |
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The Cellular and Extra-Cellular Proteomic Signature of Human Dopaminergic Neurons Carrying the LRRK2 G2019S Mutation |
| 在人类多巴胺能神经元中的形态学分析表明，线粒体解偶联具有神经保护作用。 |
Gorgogietas, V. |
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Morphological profiling in human dopaminergic neurons identifies mitochondrial uncoupling as a neuroprotective effect |
| 在皮质发育过程中对Emx2和Dmrta2合作的新见解以及Dmrta2在脉络丛功能中的证据 |
Anirudhan, J. |
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Novel insights into Emx2 and Dmrta2 cooperation during cortex development and evidence for Dmrta2 function in choroid plexus |
| 通过融合远端肾单位与输尿管芽，将收集系统整合入肾脏类器官。 |
Shi, M. |
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N/A |
Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud. |
| 调节DNA Polα可增强跨物种细胞重编程 |
Ranjan, R. |
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Modulating DNA Polα Enhances Cell Reprogramming Across Species |
| 社交隔离加剧斑马鱼中adgrl3.1相关的外化和内化行为 |
Fontana, B. D. |
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Social Isolation Intensifies adgrl3.1-Related Externalizing and Internalizing Behaviors in Zebrafish |
| 一种基于沙漠蚂蚁（Melophorus bagoti）导航行为的心理物理学视觉方法 |
deeti, s. |
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N/A |
A Method for Visual Psychophysics based on the Navigational Behaviour of Desert Ants (Melophorus bagoti) |
| 人类结构组合泛化的一种神经机制 |
Luettgau, L. |
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N/A |
A neural mechanism for compositional generalization of structure in humans |
| 在少数活跃神经元的情况下，群体编码中的偏差 |
Keemink, S. W. |
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N/A |
Biases in population codes with a few active neurons |
| 运动诱导的保留运动表现不伴有神经保护作用的小鼠帕金森病模型 |
Skelton, H. M. |
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Exercise Evokes Retained Motor Performance without Neuroprotection in a Mouse Model of Parkinson's Disease |
| 人类视觉运动区域FST的功能定位 |
Wen, P. |
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Functional localization of visual motion area FST in humans |
| 染色质重塑因子BRG1招募亨廷顿蛋白修复神经元中的DNA双链断裂 |
Pradhan, S. |
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Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons |
| 一个统一的啮齿动物图谱揭示了背侧迷走复合体的细胞复杂性和进化分歧 |
Hes, C. |
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N/A |
A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex |
| 海马体中的γCaMKII多巴胺化促进了突触到核的信号传导和记忆形成 |
Stewart, A. F. |
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Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation |
| IGF-1和胰岛素受体在LepRb神经元中共同调节身体生长、骨质量、生殖和代谢。 |
Wang, M. |
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IGF-1 and insulin receptors in LepRb neurons jointly regulate body growth, bone mass, reproduction, and metabolism |
| 米诺环素和N-乙酰半胱氨酸增加蛋白激酶Mζ表达，恢复小鼠闭合性脑损伤后的晚期长时程增强效应和空间学习能力 |
Nikulina, E. |
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N/A |
Increased protein kinase Mζ expression by Minocycline and N-acetylcysteine restoreslate-phase long-term potentiation and spatial learning after closed head injury in mice |
| 脊髓横断与运动速度对猫后肢肌肉协同作用的影响 |
Klishko, A. |
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EFFECTS OF SPINAL TRANSECTION AND LOCOMOTOR SPEED ON MUSCLE SYNERGIES OF THE CAT HINDLIMB |
| 通过无监督分割和聚类惯性信号对啮齿动物行为进行精细分解 |
Fayat, R. |
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N/A |
Fine decomposition of rodent behavior via unsupervised segmentation and clustering of inertial signals |
| 工作记忆预测听觉序列的长期识别：已验证预测与预测误差之间的分离 |
Bonetti, L. |
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Working memory predicts long-term recognition of auditory sequences: Dissociation between confirmed predictions and prediction errors |
| 血红蛋白α是一种氧化还原敏感的线粒体相关蛋白，存在于T淋巴细胞中。 |
Reed, E. C. |
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N/A |
Hemoglobin alpha is a redox-sensitive mitochondrial-related protein in T-lymphocytes |
| ICOS限制了耗竭PD-1+ CD8 T细胞的记忆样特性和功能 |
Humblin, E. |
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ICOS limits memory-like properties and function of exhausted PD-1+ CD8 T cells |
| 从摄取膨胀聚苯乙烯的黄粉虫幼虫（鞘翅目：拟步甲科）肠道中分离出的肺炎克雷伯菌 |
Caruajulca-Marin, L. |
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N/A |
Klebsiella pneumoniae isolated from the intestines of Tenebrio molitor larvae (Coleoptera: Tenebrionidae) that consume expanded polystyrene |
| 揭示铜绿假单胞菌对亚胺培南耐药性的蛋白质组学图谱：临床菌株与对照菌株的比较研究 |
Eidsaa, M. |
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N/A |
Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains |
| 1 白腿虾养殖中生产力的微生物组决定因素 |
Shan, X. |
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N/A |
1 Microbiome determinants of productivity in whiteleg shrimp aquaculture |
| 猴痘病毒蛋白质组的全面突变景观分析 |
Ozaktas, T. |
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N/A |
Comprehensive Mutational Landscape Analysis of Monkeypox Virus Proteome |
| Mpox mRNA-1769疫苗抑制正痘病毒在鼻内、直肠和皮内接种部位的复制 |
Cotter, C. A. |
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N/A |
Mpox mRNA-1769 Vaccine Inhibits Orthopoxvirus Replication at Intranasal, Intrarectal, and Cutaneous Sites of Inoculation |
| 5'和3' UTRs在SARS-CoV-2基因组包装中的作用 |
Zhang, Z. |
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Involvement of 5' and 3' UTRs on SARS-CoV-2 Genome Packaging |
| 化学修饰核苷类似物对SARS-CoV-2 RNA聚合酶的链终止效应 |
Yang, L. |
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Chain Termination Effects of Chemically Modified Nucleoside Analogs on SARS-CoV-2 RNA Polymerase |
| MdLRR-RLK1-MdATG3模块通过自噬增强苹果对非生物胁迫的抗性 |
Chen, W.-J. |
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MdLRR-RLK1-MdATG3 module enhances the resistance of apples to abiotic stress via autophagy |
| 深度学习揭示了多模板PCR中序列特异性扩增偏倚 |
Gimpel, A. L. |
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Deep learning uncovers sequence-specific amplification bias in multi-template PCR |
| 尿液蛋白质组中的病毒片段：发热病因的新线索 |
Gao, Y. |
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N/A |
Viral fragments in the urine proteome: New clues to the cause of fever |
| 外生菌根真菌黄孢乳牛肝菌（Suillus luteus）在原生和引入种群中的生物合成基因簇多样性 |
Allen, B. M. |
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N/A |
Biosynthetic Gene Cluster Diversity Across Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus |
| 野生环境中个体和群体社会行为的分级选择 |
Philson, C. S. |
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N/A |
Multilevel selection on individual and group social behaviour in the wild |
| 来自木质纤维素影响环境的高质量Bathyarchaeia宏基因组组装基因组揭示了代谢和进化机制。 |
Nesbo, c. L. |
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N/A |
High quality Bathyarchaeia MAGs from lignocellulose-impacted environments elucidate metabolism and evolutionary mechanisms. |
| 谷氨酸激酶的纤维化及脯氨酸抑制作用 |
Zhang, T. |
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N/A |
Filamentation and proline inhibition of glutamate kinase |
| 动态金属配位调控自由基卤化酶的化学选择性 |
Kissman, E. N. |
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N/A |
Dynamic metal coordination controls chemoselectivity in radical halogenases |
| 从大肠杆菌中高效生产功能性前溶菌素 |
Pham, Q. |
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N/A |
Efficient production of functional proaerolysin from E.coli |
| 一个内在无序的RNA结合区域提供了局部目标选择性，并且对LARP6的功能至关重要。 |
Capraro, F. |
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An intrinsically disordered RNA-binding region provides local target selectivity and is essential for LARP6 function. |
| 鉴定出胱氨酸代谢调控因子（CymR）衍生的五肽作为金黄色葡萄球菌O-乙酰-ʟ-丝氨酸硫醇酶（CysK）的纳摩尔抑制剂 |
Pederick, J. L. |
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N/A |
Identification of cysteine metabolism regulator (CymR)-derived pentapeptides as nanomolar inhibitors of Staphylococcus aureus O-acetyl-ʟ-serine sulfhydrylase (CysK) |
| 羊双心室心力衰竭中的三尖瓣不适应：后叶和间隔叶 |
Kostelnik, C. J. |
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N/A |
Tricuspid valve maladaptation in sheep with biventricular heart failure: The posterior and septal leaflets |
| 设计和生物工程改造CDR，使其对SARS-CoV-2 Omicron变体的受体结合域（RBD）具有更高的亲和力 |
Singh, V. |
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N/A |
Designing and bioengineering of CDRs with higher affinity against receptor-binding domain (RBD) of SARS-CoV-2 Omicron variant |
| TX-Phase：在可信执行环境中对私有基因组进行安全分阶段处理 |
Dokmai, N. |
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N/A |
TX-Phase: Secure Phasing of Private Genomes in a Trusted Execution Environment |
| 通过调节ROCK克服癌细胞对OXPHOS抑制的代谢适应，并驱动协同的抗肿瘤活性 |
Blazanin, N. |
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N/A |
Therapeutic modulation of ROCK overcomes metabolic adaptation of cancer cells to OXPHOS inhibition and drives synergistic anti-tumor activity |
| 长期饮食暴露于邻苯二甲酸盐混合物会增强雌激素和β-连环蛋白信号通路，导致小鼠子宫内膜增生。 |
Shukla, R. |
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N/A |
Long-term dietary exposure to a mixture of phthalates enhances estrogen and beta-catenin signaling pathways, leading to endometrial hyperplasia in mice |
| 特定情境下基因组规模代谢模型的修改与分析：以甲烷利用微生物底盘为例 |
Kulyashov, M. A. |
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N/A |
Modification and Analysis of Context-Specific Genome-Scale Metabolic Models: Methane-Utilizing Microbial Chassis as a Case Study |