| 多感官序列预测背后的振荡多时间尺度机制 |
Wang, P. |
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N/A |
Oscillatory multi-timescale mechanisms underlying multisensory sequence prediction |
| 使用“AngioTag”斑马鱼在体内分析内皮翻译组 |
Miller, M. F. |
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N/A |
Profiling the endothelial translatome in vivo using 'AngioTag' zebrafish |
| 基于探索的学习稳定控制器预测运动适应 |
Seethapathi, N. |
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N/A |
Exploration-based learning of a stabilizing controller predicts locomotor adaptation |
| 损伤后存活的DA SN神经元中Kv4.3介导的节律性可塑性与全内源性放电范围的恢复相关 |
Kovacheva, L. |
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N/A |
Recovery of the full in vivo firing range in post-lesion surviving DA SN neurons associated with Kv4.3-mediated pacemaker plasticity |
| 超越梯度：干扰和泛化的分解、几何控制 |
Scott, D. N. |
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N/A |
Beyond gradients: Factorized, geometric control of interference and generalization |
| 微卫星密度图谱展示了完整参考人类基因组中的短串联重复聚集情况 |
Xia, Y. |
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N/A |
Microsatellite Density Landscapes Illustrate Short Tandem Repeats Aggregation in The Complete Reference Human Genome |
| 通过多步行者监督分子动力学（mwSuMD）解决的隐藏GPCR结构转变 |
Deganutti, G. |
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N/A |
Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD) |
| 快速解聚和纤毛蛋白的力学敏感性支持在网格蛋白介导的内吞作用中快速周转 |
Mousavi, S. I. |
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N/A |
Fast actin disassembly and fimbrin mechanosensitivity support rapid turnover during clathrin-mediated endocytosis |
| 等压交联质谱技术用于研究蛋白质及其复合物的构象和结构变化 |
Ranish, J. |
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N/A |
Isobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and complexes |
| 铁死亡整合线粒体功能障碍和病理性炎症以促进肺动脉高压 |
Kazmirczak, F. |
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N/A |
Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension |
| 改进的排列检验方法能够在非平稳时间序列的重复次数有限的情况下，检测出它们之间的依赖关系。 |
Yuan, A. E. |
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Improved permutation tests enable detection of dependence between nonstationary time series despite limited numbers of replicates |
| 改进的排列检验方法能够在非平稳时间序列之间检测到依赖关系，即使重复次数有限。 |
Yuan, A. E. |
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N/A |
Improved permutation tests enable detection of dependence between nonstationary time series despite limited numbers of replicates |
| NEURD 提供连接组学的自动校对和特征提取功能。 |
Celii, B. |
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N/A |
NEURD offers automated proofreading and feature extraction for connectomics |
| mosna揭示了不同类型的细胞相互作用，这些相互作用可预测对免疫疗法的反应和癌症中的生存情况。 |
Coullomb, A. |
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N/A |
mosna reveals different types of cellular interactions predictive of response to immunotherapies and survival in cancer |
| PAPET：从PacBio SequelII数据中识别5-甲基胞嘧啶的高效算法集合 |
Groux, R. |
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PAPET: a collection of performant algorithms to identify 5-methyl cytosine from PacBio SequelII data |
| 皮质回路中实时学习的神经最小作用原理 |
Senn, W. |
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N/A |
A neuronal least-action principle for real-time learning in cortical circuits |
| 将生物相互作用纳入生态位分析中，揭示了小丑鱼群落组成的模式 |
Garcia, A. |
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N/A |
Integrating Biotic Interactions In Niche Analyses Unravels Patterns Of Community Composition in Clownfishes |
| 逆转弱碱性药物的质子化作用极大地增强了其细胞内扩散，并减少了溶酶体的隔离。 |
DEY, D. |
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N/A |
Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration |
| METASPACE-ML：利用机器学习进行成像质谱的特定背景代谢物注释 |
Wadie, B. |
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N/A |
METASPACE-ML: Context-specific metabolite annotation for imaging mass spectrometry using machine learning |
| 睡眠依赖性记忆过程中RNA加工基因的调控 |
Li, Y. |
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Modulation of RNA processing genes during sleep-dependent memory |
| 肌纤维特异性敲除TGF-β I型受体可引发肌肉肥大，并促进肌肉收缩和氧化代谢。 |
Shi, A. |
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N/A |
Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism |
| 人的知识在独立的大脑系统中分别通过外向参照系和内向参照系进行独立编码。 |
Chavez, R. S. |
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N/A |
Person knowledge is independently encoded by allocentric and egocentric reference frames within separate brain systems |
| 物体、面孔和空间：个体行为差异所体现的视觉物体知觉的组织原则 |
Sigurdardottir, H. M. |
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N/A |
Objects, faces, and spaces: Organizational principles of visual object perception as evidenced by individual differences in behavior |
| CENP-E通过对抗Aurora激酶来促进端对端附着，从而启动染色体排列。 |
Vukusic, K. |
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N/A |
CENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on attachments |
| BioMANIA：通过对话简化生物信息学数据分析 |
Dong, Z. |
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N/A |
BioMANIA: Simplifying bioinformatics data analysis through conversation |
| 锌指同源盒-3（ZFHX3）调控视交叉上核中全基因组的每日基因表达 |
Bafna, A. |
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Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus |
| Epiregulon：推断单细胞转录因子活性以预测药物反应和细胞状态的驱动因素 |
Wlodarczyk, T. |
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N/A |
Epiregulon: Inference of single-cell transcription factor activity to predict drug response and drivers of cell state |
| 药物输送的动力学决定了细菌对抗生素反应的进化过程 |
Crow, J. C. |
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Dynamics of drug delivery determines course of evolution of antibiotic responses in bacteria |
| 在14特斯拉场强下进行高分辨率清醒小鼠功能性磁共振成像 |
Hike, D. |
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N/A |
High-resolution awake mouse fMRI at 14 Tesla |
| eMOSAIC：多模态分布外不确定性量化简化了大规模多药理学研究 |
Badkul, A. |
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eMOSAIC: Multi-modal Out-of-distribution Uncertainty Quantification Streamlines Large-scale Polypharmacology |
| 昼夜节律神经肽PDF对活动节律具有性别二态性效应 |
Iyer, A. R. |
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N/A |
The Circadian Neuropeptide PDF has Sexually Dimorphic Effects on Activity Rhythms |
| 模拟安大略湖近岸与离岸水交换 |
Hlevca, B. |
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N/A |
Modeling nearshore-offshore water exchange in Lake Ontario |
| 灵长类大脑尺寸/身体尺寸关系中进化滞后的重要性 |
Dunbar, R. I. M. |
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Significance of Evolutionary Lags in the Primate Brain Size/Body Size Relationship |
| 一种通用且有效的去条纹变分方法：应用于光片显微镜、聚焦离子束扫描电镜和遥感图像 |
Rottmayer, N. |
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N/A |
A universal and effective variational method for destriping: application to light-sheet microscopy, FIB-SEM and remote sensing images |
| Hill-Robertson干扰可能会影响对高度自交物种中新突变适应性效应的推断 |
Daigle, A. |
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N/A |
Hill-Robertson interference may bias the inference of fitness effects of new mutations in highly selfing species |
| 在视觉受损的大脑中，从感官到知觉的盲文字母表征的转变 |
Haupt, M. |
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N/A |
The transformation of sensory to perceptual braille letter representations in the visually deprived brain |
| 保护计划下小种群基因组多样性的趋势：以两种法国鸡品种为例的研究 |
Bortoluzzi, C. |
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N/A |
Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds |
| 高效生成蛋白质口袋的工具——PocketGen |
Zhang, Z. |
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N/A |
Efficient Generation of Protein Pockets with PocketGen |
| 在情景记忆的形成和回忆过程中，显著网络、默认模式网络和前顶叶网络的电生理动力学：一项多实验的iEEG重复研究 |
Das, A. |
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N/A |
Electrophysiological dynamics of salience, default mode, and frontoparietal networks during episodic memory formation and recall: A multi-experiment iEEG replication |
| 基因背景和发育状态对胶质母细胞瘤患者来源细胞信号通路及治疗反应的影响 |
Berezovsky, A. D. |
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N/A |
Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells |
| 使用TREAT和otter分析长读长测序平台上的串联重复复杂性 |
Tesi, N. |
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N/A |
Characterising tandem repeat complexities across long-read sequencing platforms with TREAT and otter |
| 转录组学和跨细胞器互补揭示了12-cis-oxo-植物二烯酸在受伤的拟南芥中有限的信号传导能力 |
Mekkaoui, K. |
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N/A |
Transcriptomics and trans-organellar complementation reveal a limited signaling capacity of 12-cis-oxo-phytodienoic acid in wounded Arabidopsis |
| 从背外侧前额叶皮质的转录组和表观组数据推断女性阿尔茨海默病患者的多种疾病进展路径的可能性 |
Honda, K. |
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N/A |
Possibilities of multiple disease progression pathways in female Alzheimer's disease patients inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex |
| 专家导航员采用基于合理复杂性的决策优先级排序，用于大规模现实世界规划 |
Fernandez Velasco, P. |
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N/A |
Expert Navigators Deploy Rational Complexity-Based Decision Prioritization for Large-Scale Real-World Planning |
| 寄生在非洲慈鲷鱼上的桡足类寄生虫Ergasilus kandti的线粒体基因组、系统发育位置及分布更新 |
Jansen, D. |
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N/A |
Mitogenomics, phylogenetic position, and updated distribution of Ergasilus kandti, an ergasilid copepod parasitizing African cichlid fishes |
| 活细胞荧光显微镜 - 高通量图像与数据分析的端到端工作流程 |
Zahumensky, J. |
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N/A |
Live Cell Fluorescence Microscopy - An End-to-End Workflow for High-Throughput Image and Data Analysis |
| MRAP2 修饰黑皮质素-4受体的信号传导和寡聚化状态。 |
Sohail, I. |
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N/A |
MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor |
| G蛋白偶联受体激酶2（GRK2）调控毛囊稳态 |
Asensio, A. |
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N/A |
The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis |
| 定义表观遗传抑制对肺癌细胞反应的异质分子图谱 |
Lin, C. |
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N/A |
Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition |
| 预测肺移植后原发性移植物功能障碍：基于机器学习的生物标志物发现 |
Nord, D. |
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N/A |
Predicting Primary Graft Dysfunction in Lung Transplantation: Machine Learning-Guided Biomarker Discovery |
| 在已发现的癌症驱动核苷酸（CDNs）中——基因、癌症类型和患者之间的分布情况 |
Zhang, L. |
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N/A |
On the discovered Cancer Driving Nucleotides (CDNs)-Distributions across genes, cancer types and patients |
| 大规模重复进化与癌症驱动核苷酸（CDNs）完全鉴定的理论 |
Zhang, L. |
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N/A |
The theory of massively repeated evolution and full identifications of Cancer Driving Nucleotides (CDNs) |
| PhyloFunc：作为元蛋白质组数据分析中一种新型生态学指标的系统发育功能距离 |
Wang, L. |
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N/A |
PhyloFunc: Phylogeny-informed Functional Distance as a New Ecological Metric for Metaproteomic Data Analysis |
| 原噬菌体与铜绿假单胞菌临床分离株的抗生素耐药性关联不频繁 |
Chang, T. H. |
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N/A |
Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates |
| 大麻二酚与益生菌的协同作用可以抑制血糖指标，增强胰岛素分泌，并缓解2型糖尿病的症状。 |
Naeini, S. E. |
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N/A |
The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes. |
| 多囊卵巢综合征小鼠模型中的GnRH脉冲发生器活性 |
Zhou, Z. |
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N/A |
GnRH pulse generator activity in mouse models of polycystic ovary syndrome |
| 一种类人轮廓整合的前馈机制 |
Doshi, F. R. |
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N/A |
A feedforward mechanism for human-like contour integration |
| 多发性硬化进展中的性别差异单细胞图谱 |
Soler-Saez, I. |
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N/A |
Single cell landscape of sex differences in the progression of multiple sclerosis |
| 选择针对不同手性RNA元件的氟化适配体 |
Dantsu, Y. |
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N/A |
Selection of Fluorinated Aptamer Targeting RNA Element with Different Chirality |
| 巨蜂鸟（Patagona spp.）（鸟类：蜂鸟科）的分类学、命名法及鉴定 |
Williamson, J. L. |
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N/A |
Taxonomy, nomenclature, and identification of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae) |
| 构建镜像RNA纳米结构以增强生物稳定性和药物递送效率 |
Zhang, Y. |
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N/A |
Construction of mirror-image RNA nanostructure for enhanced biostability and drug delivery efficiency |
| 基因功能在随机基因沉默的瞬间被揭示 |
Gupta, S. |
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N/A |
Gene Function Revealed at the Moment of Stochastic Gene Silencing |
| 桡足类化学信号对两种拟菱形藻细胞内和细胞外毒素的影响 |
Pourdanandeh, M. |
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N/A |
Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis |
| 最近的研究表明，气味体验能够有选择性地调节小鼠嗅球中嗅觉敏感度，这种调节作用跨越了嗅球中的小球输出层。 |
Subramanian, N. |
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N/A |
Recent odor experience selectively modulates olfactory sensitivity across the glomerular output in the mouse olfactory bulb |
| 线粒体叶酸代谢紊乱会导致线粒体DNA泄漏，并激活细胞凋亡或炎症通路。 |
Hwang, S. |
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N/A |
Disruption of mitochondrial folate metabolism leads to mitochondrial DNA leakage and activation of apoptotic or inflammatory pathways |
| 质粒病毒维持使细菌种群从感染中恢复并实现病毒-细菌共存 |
Sanchez-Martinez, R. |
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N/A |
Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence |
| 大肠杆菌细胞中DnaA和DNA的相对分布及其表型变异性的因素 |
Namboodiri, S. K. |
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N/A |
Relative Distribution of DnaA and DNA in Escherichia coli Cells as a Factor of Their Phenotypic Variability |
| 在肢体发育过程中，En1的时间表达错误会导致不同的表型。 |
Ringel, A. R. |
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N/A |
Temporal misexpression of En1 during limb development causes distinct phenotypes |
| 一类新的受体：脂质通过其膜锚定物调节哺乳动物Gsα刺激的腺苷酸环化酶活性 |
Landau, M. |
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N/A |
A new class of receptors: Lipids regulate mammalian Gsalpha-stimulated adenylyl cyclase activities via their membrane anchors |
| 通过一种具有可解释注意力单元的新型深度学习模型探索核定位信号宇宙 |
Li, Y. |
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N/A |
Discovering nuclear localization signal universe through a novel deep learning model with interpretable attention units |
| 网格蛋白介导的内吞作用中的囊泡化途径 |
Wang, X. |
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N/A |
Vesiculation pathways in clathrin-mediated endocytosis |
| 乳腺癌上皮-间充质转化及器官特异性转移中三维基因组结构的重新排列 |
Das, P. |
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N/A |
Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism |
| 人类从腹侧壳核到运动皮层区域的假定开环电路的解离研究 I：高分辨率连接组学 |
Rizor, E. J. |
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N/A |
Dissociation of putative open loop circuit from ventral putamen to motor cortical areas in humans I: high-resolution connectomics |
| 评估生理指标在通过比较问题测试（CQT）检测欺骗和真实性中的应用 |
Rashid, A. M. S. |
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N/A |
Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT) |
| DNMT1介导的抑制性中间神经元迁移调控影响皮层结构和功能 |
Reichard, J. |
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N/A |
DNMT1-Mediated Regulation of Inhibitory Interneuron Migration Impacts Cortical Architecture and Function |
| 转录调控因子HcpR的全长结构及其与血红素的结合 |
Belvin, B. R. |
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N/A |
Full-length structure and heme binding in the transcriptional regulator HcpR |
| 肌动蛋白丝切割和封端的机制：凝溶胶蛋白的作用 |
Barrie, K. R. |
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N/A |
Mechanism of Actin Filament Severing and Capping by Gelsolin |
| 神经内分泌通过果蝇血管壁龛调控肠道再生 |
Medina, A. |
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N/A |
Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila. |
| 神经营养因子artemin及其受体GFRα3通过离子通道TRPM8介导偏头痛样疼痛。 |
Yang, C. |
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N/A |
The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8 |
| 通过考虑树突计算来克服运动传感器模型的局限性 |
Luna, R. |
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N/A |
Overcoming the limitations of motion sensor models by considering dendritic computations |
| 海马体中人口活动的稀疏性在三突触回路和背腹轴上与任务无关。 |
Lee, J. Q. |
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N/A |
Sparsity of population activity in the hippocampus is task-invariant across the trisynaptic circuit and dorsoventral axis |
| 在斑马鱼胚胎中，快肌纤维的生长与Mylpf剂量的增加成比例 |
Adekeye, T. E. |
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N/A |
Fast-twitch myofibrils grow in proportion to Mylpf dosage in the zebrafish embryo |
| 机器学习时代的整合建模：HADDOCK策略在CAPRI第47至55轮中的总结 |
Reys, V. |
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N/A |
Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55 |
| 用于结构系统发育学的通用替换矩阵。 |
Garg, S. G. |
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N/A |
A general substitution matrix for structural phylogenetics. |
| 探索同步的边缘：在行为中的猴子中，皮层活动短暂地滑入慢波 |
Pazienti, A. |
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N/A |
Probing The Edge Of Synchronization: Cortical Activity Transiently Slips Into Slow Waves In Behaving Monkeys |
| 从DNA序列预测和功能解析染色体间基因组结构的双胞胎方法 |
Jha, A. |
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N/A |
Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC |
| 来自精神分裂症个体的hiPSC衍生的星形胶质细胞促进了类似小胶质细胞的吞噬作用和趋化性的改变 |
Cardozo, P. L. |
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N/A |
hiPSC-derived astrocytes from individuals with schizophrenia promote alterations in phagocytosis and chemotaxis of microglial-like cells |
| 使用神经网络解决巴布亚新几内亚人口的非洲起源事件 |
Mondal, M. |
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N/A |
Resolving out of Africa event for Papua New Guinean population using neural network |
| BCR交联有选择性地抑制IgE类别转换重组 |
Wade-Vallance, A. K. |
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N/A |
BCR ligation selectively inhibits IgE class switch recombination |
| 寄生传播时间选择塑造了宿主冈比亚按蚊的转录反应，并提示免疫逃避 |
Silva, L. M. |
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N/A |
Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion |
| scooby：在单细胞分辨率下从DNA序列建模多模态基因组特征 |
Hingerl, J. C. |
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N/A |
scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution |
| 环节动物组蛋白基染色质调控的演化与发展动力 |
Martin-Zamora, F. M. |
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N/A |
The evolution and developmental dynamics of histone-based chromatin regulation in Annelida |
| 地下动物的隐花色素-1（Cryptochrome-1）中反复出现的突变，改变了行为和分子层面的昼夜节律。 |
Swaminathan, A. |
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N/A |
A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms |
| 苜蓿（Medicago truncatula）中的CORYNE基因调控花序分生组织分支、营养信号传递以及丛枝菌根共生关系 |
Orosz, J. |
PDF |
N/A |
Medicago truncatula CORYNE regulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis |
| 田间作物转录组模型通过在系统控制的环境中的测量得到了增强 |
Hashida, Y. |
PDF |
N/A |
Field-crop transcriptome models are enhanced by measurements in systematically controlled environments |
| 多病虫抗性番茄品系对白粉虱传播病毒TYLCV积累的响应 |
Prabhakar, S. S. |
PDF |
N/A |
The response of multi-disease and insect-resistant tomato lines to the accumulation of TYLCV, a whitefly-transmitted virus |
| PEBP1 增强线粒体功能障碍引发的整合应激反应 |
Cheng, L. |
PDF |
N/A |
PEBP1 amplifies mitochondrial dysfunction induced integrated stress response |
| 定义不同代谢条件下人类脂肪组织的血管龛 |
AlZaim, I. |
PDF |
N/A |
Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions |
| LINE1促进核内区室化以抑制胚胎干细胞中的8细胞状态 |
Zhang, J. |
PDF |
N/A |
LINE1 promotes nuclear compartmentalization to repress the 8-cell state in embryonic stem cells |
| BEDMS：一种基因组区域属性元数据标准化工具 |
Tambe, S. |
PDF |
N/A |
BEDMS: A metadata standardizer for genomic regionattributes |
| 矮牵牛杂交种的染色体水平基因组组装与注释 |
Saei, A. |
PDF |
N/A |
Chromosome-level Genome Assembly and Annotation of Petunia hybrida |
| 早期生活不可预测性对青少年海马和杏仁核对新奇刺激反应的性别特异性影响 |
Davis, E. P. |
PDF |
N/A |
Sex-specific effects of early life unpredictability on hippocampal and amygdala responses to novelty in adolescents |
| 不饱和脂质作为控制穴样内陷形成和解体的关键因素 |
Wu, Y. |
PDF |
N/A |
Unsaturated lipids as key control points for caveola formation and disassembly |
| 瞬时Notch激活将多能干细胞衍生的心肌细胞转化为浦肯野纤维命运 |
Gonzalez, D. M. |
PDF |
N/A |
Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate |
| 动态系统理论指导下的细胞分化景观学习 |
Howe, A. E. S. |
PDF |
N/A |
Dynamical systems theory informed learning of cellular differentiation landscapes |
| 物种共现模型的样本量考虑。 |
Cowans, A. |
PDF |
N/A |
Sample size considerations for species co-occurrence models. |
| 温度与资源之间的相互作用如何从种群扩展到群落 |
Kremer, C. T. |
PDF |
N/A |
How interactions between temperature and resources scale from populations to communities |
| 严格（在）验证生态模型 |
Song, C. |
PDF |
N/A |
Rigorous (in)validation of ecological models |
| 杂合缺失对拟南芥表型变化及剂量补偿的影响 |
Ikoma, T. |
PDF |
N/A |
Effect of heterozygous deletions on phenotypic changes and dosage compensation in Arabidopsis thaliana |
| 比较泛基因组学揭示了临床相关成员在镰刀菌属物种复合体中的不同适应性 |
Brassington, P. J. |
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N/A |
Comparative pan-genomics reveals divergent adaptations in clinically-relevant members of the Fusarium solani species complex |
| 探索单细胞数据中的群体特异性技术变异模式 |
Zhou, Y. |
PDF |
N/A |
Exploring group-specific technical variation patterns of single-cell data |
| PoreVision：一种用于提升扫描电镜孔隙分析效率和准确性的程序 |
Olevsky, L. M. |
PDF |
N/A |
PoreVision: A Program for Enhancing Efficiency and Accuracy in SEM Pore Analyses |
| DiffPaSS - 使用软分数进行高性能可微蛋白质序列配对 |
Lupo, U. |
PDF |
N/A |
DiffPaSS - High-performance differentiable pairing of protein sequences using soft scores |
| 通过表征学习和稀疏模型发现探索生物系统的控制方程 |
Sadria, M. |
PDF |
N/A |
Discovering Governing Equations of Biological Systems through Representation Learning and Sparse Model Discovery |
| GuaCAMOLE：GC偏倚感知估计提高了宏基因组物种丰度的准确性 |
Holcik, L. |
PDF |
N/A |
GuaCAMOLE: GC-bias aware estimation improves the accuracy of metagenomic species abundances |
| 揭示半乳糖凝集素-1与脂质膜结合的GM1特异性 |
Scollo, F. |
PDF |
N/A |
Unraveling the GM1 specificity of Galectin-1 binding to lipid membranes |
| 扩展自动化多构象配体建模至大环化合物和片段 |
Flowers, J. |
PDF |
N/A |
Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments |
| 没有基因振荡器或外部驱动的生物振荡 |
Vandenbroucke, V. |
PDF |
N/A |
Biological oscillations without genetic oscillator or external forcing |
| 一种新型方法用于在单细胞分辨率下表征细胞间相互作用，揭示了感染期间血液T细胞-单核细胞复合物的独特特征 |
Kang, N. |
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N/A |
A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes during infection |
| FcγR和CD9依赖的丘脑突触吞噬小胶质细胞驱动皮层脑损伤后的认知障碍 |
Matoba, K. |
PDF |
N/A |
FcγR- and CD9-dependent synapse engulfing microglia in the thalamus drives cognitive impairment following cortical brain injury |
| 溶酶体LRRC8复合物调节溶酶体pH值、形态及全身葡萄糖代谢 |
Kumar, A. |
PDF |
N/A |
Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism |
| 磷脂酶D的辅助域调控其在果蝇光感受器中的定位和活性 |
Naik, A. |
PDF |
N/A |
The accessory domains of Phospholipase D regulate its localization and activity in Drosophila photoreceptors |
| 线粒体移植：适应性生物增强 |
Lu, X. |
PDF |
N/A |
Mitochondrial Transplantation: Adaptive Bio-enhancement |
| 在裂殖酵母中，细胞质内的扩散随着细胞大小的增加而增加。 |
Tan, C. |
PDF |
N/A |
Intracellular diffusion in the cytoplasm increases with cell size in fission yeast |
| 幼稚多能性退出包含一个由脂质代谢引发的基因组完整性检查点。 |
de Souza, R. A. |
PDF |
N/A |
The exit of naïve pluripotency contains a lipid metabolism-induced checkpoint for genome integrity. |
| 内共生体以温度依赖的方式影响瓢虫对蚜虫的捕食率 |
Thomsen, K. B. |
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N/A |
Endosymbionts impact ladybird predation rates of aphids in a temperature-dependent manner |
| 日均温度可以比速率累加更好地预测疟疾传播的热限。 |
Shocket, M. S. |
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N/A |
Mean daily temperatures can predict the thermal limits of malaria transmission better than rate summation |
| 传统品种环境数据在气候适应型玉米育种中的应用 |
Li, F. |
PDF |
N/A |
The utility of environmental data from traditionalvarieties for climate-adaptive maize breeding |
| 不同衬纸材料和浸液对埃及伊蚊（双翅目：蚊科）雌蚊产卵偏好的影响 |
Momen, M. |
PDF |
N/A |
Effect of different lining paper materials and infusions on oviposition preference of Aedes aegypti (Diptera: Culicidae) gravid mosquitoes |
| Msp1介导的脂质双层中底物提取的能量需求和机制可塑性 |
Smith, B. |
PDF |
N/A |
Energetic requirements and mechanistic plasticity in Msp1-mediated substrate extraction from lipid bilayers |
| SMART MRS：一种用于GABA编辑磁共振波谱（MRS）的模拟MEGA-PRESS伪影工具箱 |
Bugler, H. |
PDF |
N/A |
SMART MRS: A Simulated MEGA-PRESS Artifacts Toolbox for GABA-edited MRS |
| 人类NDPK六聚体结构、稳定性和相互作用的动态建模 |
Lim, Y. Y. |
PDF |
N/A |
Modelling dynamics of human NDPK hexamer structure, stability and interactions |
| 用于监测Cas9核酸内切酶活性的固态纳米孔实时检测 |
Chau, C. C. |
PDF |
N/A |
Solid-State Nanopore Real Time Assay for Monitoring Cas9 Endonuclease Reactivity |
| 浓缩LiCl水溶液中DNA的性质表明向C-DNA的转变 |
Mazur, A. |
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N/A |
Properties of DNA in concentrated aqueous solutions of LiCl suggest transition to C-DNA |
| 宫内生长受限对发育中的胰腺免疫系统的影响 |
Golden, T. N. |
PDF |
N/A |
The effect of intrauterine growth restriction on the developing pancreatic immune system |
| CanDrivR-CS：一种用于区分复发性和罕见变异的癌症特异性机器学习框架 |
Francis, A. |
PDF |
N/A |
CanDrivR-CS: A Cancer-Specific Machine Learning Framework for Distinguishing Recurrent and Rare Variants |
| TBX15调控脂肪组织中免疫应答基因网络，并改变杂合敲除小鼠的脂肪质量和脂肪库重量 |
Zolkiewski, L. |
PDF |
N/A |
TBX15 regulates a network of immune response genes in adipose tissue and alters fat mass and depot weight in heterozygous knockout mice |
| 一种一步法协议，用于制备适用于原位活细胞应用和超分辨率成像的不透光荧光HaloTag底物 |
Rossmann, K. |
PDF |
N/A |
A one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging |
| PointTree：单神经元长程轴突投射的自动精确重建 |
Cai, L. |
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N/A |
PointTree: Automatic and accurate reconstruction of long-range axonal projections of single-neuron |
| 弥合秀丽隐杆线虫的连接组与全脑活动之间的差距 |
Creamer, M. S. |
PDF |
N/A |
Bridging the gap between the connectome and whole-brain activity in C. elegans |
| 构建小鼠大脑树突微环境的图谱有助于发现解剖布局、投射目标和神经元转录组特征之间的潜在关联。 |
Liu, Y. |
PDF |
N/A |
Constructing a Mouse Brain Atlas of Dendritic Microenvironments Helps Discover Hidden Associations Between Anatomical Layout, Projection Targets and Transcriptomic Profiles of Neurons |
| Tau P301S转基因小鼠出现步态和眼球运动障碍，类似于进行性核上性麻痹 |
Creed, R. B. |
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N/A |
Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy |
| 低强度聚焦超声参数在人类神经调控中的研究 |
Ennasr, A. |
PDF |
N/A |
Examination of low-intensity focused ultrasound parameters for human neuromodulation |
| 视觉体验评估工具：一种用于量化视觉体验的近视研究仪器 |
Sullivan, D. |
PDF |
N/A |
The Visual Experience Evaluation Tool: A Myopia Research Instrument for Quantifying Visual Experience |
| SAPAP3小鼠模型在强迫症发病前的特征：行为、神经可塑性及裸盖菇素治疗 |
Lazar, M. |
PDF |
N/A |
Premorbid Characteristics of the SAPAP3-Mouse Model of Obsessive-Compulsive Disorder: Behavior, Neuroplasticity, and Psilocybin Treatment |
| TWINKLE：一款用于教学和研究的开源双光子显微镜 |
Schottdorf, M. |
PDF |
N/A |
TWINKLE: An open-source two-photon microscope for teaching and research |
| 鼠标爪：逆转翻译FINGER多模态生活方式干预增强了成年野生型雌性小鼠的突触可塑性和认知能力 |
Alanko, V. |
PDF |
N/A |
Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice |
| 成年神经发生和焦虑的自然变异预测近交系小鼠的等级地位 |
Grieco, F. |
PDF |
N/A |
Natural variations of adult neurogenesis and anxiety predict hierarchical status of inbred mice |
| PHluorin-偶联的次级纳米抗体作为测量突触小泡胞外和胞内吞吐的工具 |
Georgiev, S. V. |
PDF |
N/A |
PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exo- and endocytosis |
| 不同体型动物的前馈和反馈控制性能受感觉运动延迟和肌肉力量能力限制的影响 |
Mohamed Thangal, S. N. |
PDF |
N/A |
Effects of sensorimotor delays and muscle force capacity limits on the performance of feedforward and feedback control in animals of different sizes |
| 嗅觉和三叉神经途径的HSV-1中枢神经系统感染与区域性小胶质细胞异质性 |
Niemeyer, C. |
PDF |
N/A |
Olfactory and Trigeminal Routes of HSV-1 CNS Infection with Regional Microglial Heterogeneity |
| 在语言产生和理解过程中，额叶-颞叶皮层中与语音声音特异性一致的脑信号。 |
Dmitrieva, X. |
PDF |
N/A |
Congruent brain signatures specific to speech sounds in fronto-temporal cortex during language production and understanding. |
| 女性一生中的全脑动态与激素变化：从生殖阶段到更年期过渡及之后 |
Escrichs, A. |
PDF |
N/A |
Whole-brain dynamics and hormonal shifts throughout women's lifespan: From reproductive stages to menopausal transition and beyond |
| 新生小鼠在出现觅食和饮水行为之前，饥饿和口渴的神经表征具有显著差异 |
Wang, D. C. |
PDF |
N/A |
Distinct Neural Representations of Hunger and Thirst in Neonatal Mice before the Emergence of Food- and Water-seeking Behaviors |
| 创伤性脑损伤加剧了酒精摄入和神经炎症，同时伴随着认知功能和胆碱能活性的下降。 |
Gangal, H. |
PDF |
N/A |
Traumatic Brain Injury Exacerbates Alcohol Consumption and Neuroinflammation with Decline in Cognition and Cholinergic Activity |
| 音乐才能调节皮层（而非脑干）对音乐三和弦处理中注意力的影响 |
MacLean, J. |
PDF |
N/A |
Musicianship modulates cortical (but not brainstem) effects of attention on processing musical triads |
| 广泛的大脑活动增加与意识受损的额叶癫痫发作有关 |
Salardini, E. |
PDF |
N/A |
Widespread brain activity increases in frontal lobe seizures with impaired consciousness |
| 神经几何学有效地表示了灵长类基底神经节中价值和模态的抽象形式。 |
Kim, H. F. |
PDF |
N/A |
Neural geometry efficiently representing abstract form of value and modality in the primate basal ganglia |
| 神经几何学有效地表示了灵长类基底神经节中价值和模态的抽象形式。 |
Hwang, S.-H. |
PDF |
N/A |
Neural geometry efficiently representing abstract form of value and modality in the primate basal ganglia |
| 经济选择中神经编码的理性注意力不足 |
Fine, J. M. |
PDF |
N/A |
Rational inattention in neural coding for economic choice |
| 人类胚胎类器官形态空间的可解释图谱揭示了原肠胚形成失败模式并预测了致畸物 |
Rufo, J. |
PDF |
N/A |
An explainable map of human gastruloid morphospace reveals gastrulation failure modes and predicts teratogens |
| 访客对灵长类动物救助中心黑猩猩（Pan troglodyte）行为的影响 |
Maurer, S. |
PDF |
N/A |
Visitor effect on the behavior of chimpanzees (pan troglodyte) at a primate rescue center |
| 内质网应激转录因子Luman/CREB3通过激活未折叠蛋白反应和胆固醇生物合成途径，是施万细胞存活和髓鞘形成能力的新型调控因子。 |
Verge, V. M. K. |
PDF |
N/A |
The ER stress transcription factor Luman/CREB3 is a novel regulator of Schwann cell survival and myelinating capacity through the activation of the unfolded protein response and cholesterol biosynthesis pathways |
| 胆碱能神经元活动通过毒蕈碱信号传导促进弥漫性中线胶质瘤的生长 |
Monje, M. |
PDF |
N/A |
Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling |
| 神经选择性的系统性变化反映了类别诊断维度所获得的重要性。 |
Luthra, S. |
PDF |
N/A |
Systematic changes in neural selectivity reflect the acquired salience of category-diagnostic dimensions |
| 产后环境富集可纠正成年小鼠早期逆境暴露导致的神经周围网形成缺陷及反转学习障碍 |
Jamwal, S. |
PDF |
N/A |
Postnatal Enrichment Corrects Deficits in Perineuronal Net Formation and Reversal Learning in Adult Mice Exposed to Early Adversity |
| 利用连续时间转移熵估计器推断脉冲神经元的有效网络 |
Shorten, D. |
PDF |
N/A |
Inferring Effective Networks of Spiking Neurons Using a Continuous-Time Estimator of Transfer Entropy |
| AKT介导的TSC2磷酸化调控刺激和组织特异性mTORC1信号传导及器官生长 |
Cormerais, Y. |
PDF |
N/A |
AKT-mediated phosphorylation of TSC2 controls stimulus and tissue-specific mTORC1 signaling and organ growth |
| Bnip3lb驱动的线粒体自噬维持了胚胎造血干细胞池的扩增 |
Meader, E. |
PDF |
N/A |
Bnip3lb-driven mitophagy sustains expansion of the embryonic hematopoietic stem cell pool |
| 间充质-上皮转变减少了肿瘤球体的增殖，但增加了免疫逃逸 |
Dimari, G. |
PDF |
N/A |
Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids |
| 脱嘧啶/脱嘌呤核酸内切酶2（APEX2/APE2）在人胚胎干细胞中对TERT的高效表达是必需的。 |
Stern, J. L. |
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N/A |
Apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2/APE2) is required for efficient expression of TERT in human embryonic stem cells. |
| 内核膜磷酸酶复合物对TGF-β/SMAD信号的抑制作用 |
Ji, Z. |
PDF |
N/A |
Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex |
| 细胞信号通过Rac和WAVE介导的机制，将Arp2/3复合物从基底侧招募到顶端，从而促进顶端收缩。 |
Zhang, P. |
PDF |
N/A |
Cell signaling facilitates apical constriction by basolaterally recruiting Arp2/3 via Rac and WAVE |
| 空间多组学揭示胰腺癌免疫治疗病理反应者中与三级淋巴结构相关的肿瘤内体液免疫微环境 |
Sidiropoulos, D. N. |
PDF |
N/A |
Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer immunotherapy pathologic responders |
| 机器学习驱动的SARS-CoV-2适应性景观模拟 |
Durumeric, A. E. P. |
PDF |
N/A |
Machine Learning Driven Simulations of SARS-CoV-2 Fitness Landscape |
| 肠道微生物群昼夜振荡节律的丧失与动脉粥样硬化的进展相关 |
Zhang, H. |
PDF |
N/A |
Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Progression of Atherosclerosis |
| 在植物体内转座子测序用于鉴定Xylella fastidiosa中的毒力基因 |
Burbank, L. P. |
PDF |
N/A |
In planta transposon sequencing for virulence gene identification in Xylella fastidiosa |
| 肠球菌属粪肠球菌菌株中β-内酰胺耐药性的进化轨迹 |
Ugalde-Silva, P. |
PDF |
N/A |
Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains |
| 在考古牙齿结石中鉴定古代抗生素抗性基因 |
Standeven, F. |
PDF |
N/A |
Identifying ancient antibiotic resistance genes in archaeological dental calculus |
| 在铜绿假单胞菌拮抗作用下，脓肿分枝杆菌的持续存在 |
Gupta, R. |
PDF |
N/A |
Mycobacterium abscessus persistence in the face of Pseudomonas aeruginosa antagonism |
| 胞外多糖聚N-乙酰葡萄糖胺（PNAG）在体内覆盖肺炎克雷伯菌。 |
Bradshaw, J. |
PDF |
N/A |
The exopolysaccharide Poly-N-Acetyl-Glucosamine (PNAG) coats Klebsiella pneumoniae in vivo |
| 一种膜结合的传送带控制着细菌第9型分泌系统的旋转方向 |
Shrivastava, A. |
PDF |
N/A |
A membrane-associated conveyor belt controls the rotational direction of the bacterial type 9 secretion system |
| 与炎症性肠病相关的肠埃希菌菌株侵袭性的遗传和微生物分析 |
Kim, J. |
PDF |
N/A |
Genetic and microbial analysis of invasiveness for Escherichia coli strains associated with inflammatory bowel disease |
| 群体感应通过依赖和不依赖于第六型分泌系统的机制调控霍乱弧菌中的平行细胞死亡途径 |
Mashruwala, A. A. |
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N/A |
Quorum sensing orchestrates parallel cell death pathways in Vibrio cholerae via Type 6 secretion dependent and independent mechanisms |
| 粪便滤液转移对坏死性小肠结肠炎的防护作用需要供体活病毒组的存在 |
Spiegelhauer, M. R. |
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N/A |
Protection against necrotizing enterocolitis by fecal filtrate transfer requires an active donor virome |
| 鼻内接种的雪貂在急性期和急性后期阶段，SARS-CoV-2的神经侵袭性和神经毒力潜能 |
Benavides, F. F. W. |
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N/A |
Neuroinvasive and neurovirulent potential of SARS-CoV-2 in the acute and post-acute phase of intranasally inoculated ferrets |
| 利用工程改造的甲烷嗜甲基菌（Methanosarcina acetivorans）从一碳化合物中生产倍半萜类化合物巴索贝内烯（bisabolene） |
Mentrup, A. |
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N/A |
Production of the sesquiterpene bisabolene from one-carbon compounds in an engineered Methanosarcina acetivorans |
| Pythia：非随机DNA修复使得CRISPR/Cas9整合和基因编辑具有可预测性 |
Naert, T. |
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N/A |
Pythia: Non-random DNA repair allows predictable CRISPR/Cas9 integration and gene editing |
| TNFSF13 不足会破坏人类结肠上皮细胞介导的 B 细胞分化 |
Ma, X. |
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TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation |
| SGLT2抑制剂通过非CaMKII依赖的机制，对糖尿病心肌病和心房颤动具有保护作用。 |
Severino, A. |
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N/A |
SGLT2 inhibitors protect against diabetic cardiomyopathy and atrial fibrillation through a CaMKII independent mechanism |
| MTALTCO1：一种由线粒体DNA编码的259个氨基酸长的替代蛋白，挑战了传统线粒体基因组学的理解。 |
Robitaille, F. |
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MTALTCO1: a 259 amino acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics. |
| 蛋白质语言模型：规模化是必要的吗？ |
Fournier, Q. |
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N/A |
Protein Language Models: Is Scaling Necessary? |
| 百日咳毒素抗体中和作用的结构基础 |
Goldsmith, J. A. |
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N/A |
Structural Basis for Antibody Neutralization of Pertussis Toxin |
| 在阿尔茨海默病中，Tau蛋白及其他聚集蛋白中发现脱水氨基酸及其交联结构 |
Markovich, S. W. |
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N/A |
Discovery of dehydroamino acids and their crosslinks in Tau and other aggregating proteins of Alzheimers disease |
| 一种综合建模方法用于线粒体嵴 |
Brown, C. M. |
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N/A |
An integrative modelling approach to the mitochondrial cristae |
| 肠道微生物组时代的人类非靶向代谢组学：乙醇与甲醇 |
Zuffa, S. |
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N/A |
Human untargeted metabolomics in the gut microbiome era: ethanol vs methanol |
| 肝源性醛糖还原酶驱动类似Warburg效应的代谢重编程，促进胰岛素抵抗、脂肪肝和肥胖 |
Song, D. |
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N/A |
Hepatic aldose reductase drives a Warburg effect-like metabolic reprogramming to promote insulin resistance, fatty liver and obesity |
| 一种用于Caldimonas thermodepolymerans的初始基因编辑工具集，这是首个嗜热聚羟基烷酸生产模型的代表。 |
Grybchuk-Ieremenko, A. |
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N/A |
An initial genome editing toolset for Caldimonas thermodepolymerans, the first model of thermophilic polyhydroxyalkanoates producer |
| 准确的超大规模基因组集多序列比对 |
Lai, X. |
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N/A |
Accurate Multiple Sequence Alignment of Ultramassive Genome Sets |
| 设计一种基于细胞内适配体的荧光生物传感器，用于追踪大肠杆菌的负担 |
Grob, A. |
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N/A |
Design of an intracellular aptamer-based fluorescent biosensor to track burden in E. coli |
| 建筑给排水系统影响饮用水微生物群的微多样性和群落构建。 |
He, H. |
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N/A |
Building plumbing influences the microdiversity and community assembly of the drinking water microbiome. |
| 针对宿主转录因子HSF1可阻止人巨细胞病毒在体外和体内的复制 |
Biswas, J. |
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N/A |
Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo |
| CLCC1促进疱疹病毒核输出过程中的膜融合。 |
Dai, B. |
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N/A |
CLCC1 promotes membrane fusion during herpesvirus nuclear egress. |
| 间歇性高频有氧-缺氧循环扰动提高废水处理过程中N2O还原酶活性 |
Zhou, X. |
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N/A |
Intermittent Perturbation with High-Frequency Aerobic-Anoxic Cycling Enhances N2O Reductase Activity during Wastewater Treatment |
| 铜绿假单胞菌PAO1的b型鞭毛蛋白糖基结构解析 |
Hensbergen, P. J. |
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N/A |
Elucidation of the glycan structure of the b-type flagellin of Pseudomonas aeruginosa PAO1 |
| 百日咳博德特氏菌的一种新型粘附素是其侵入上皮细胞的关键 |
Gollan, M. |
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N/A |
A Novel Adhesin of B. pertussis is Key to Colonisation of Epithelial Cells |
| CHAMP1复合体指导异染色质组装并促进同源定向DNA修复。 |
D'Andrea, A. D. |
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CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair |
| 基于CRISPR的转录激活系统中激活子表达的细胞毒性 |
Maddineni, A. |
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N/A |
Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems |
| 适用于原代干细胞多模式CRISPR基因编辑的多功能细胞穿透肽 |
Graham, J. P. |
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N/A |
Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells |
| PDZ介导的底物招募是PP1-Neurabin特异性去磷酸化4E-BP1的主要决定因素。 |
Fedoryshchak, R. O. |
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PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1dephosphorylation by PP1-Neurabin |
| 海马体对替代可能性的表征是灵活生成的，以满足认知需求。 |
Comrie, A. E. |
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Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands |
| 母子二元互动塑造了儿童的社会大脑和心智理论 |
Li, L. |
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N/A |
Mother-child dyadic interactions shape children's social brain and theory of mind |
| 肾上腺素能信号调控星形胶质细胞对神经递质的反应性及对神经活动的控制 |
Guttenplan, K. A. |
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Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity |
| 主要精神疾病的人类神经发育模型中GABA能神经元失调 |
Guo, Z. |
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N/A |
GABAergic neuron dysregulation in a human neurodevelopmental model for major psychiatric disorders |
| 罗马殖民与迁徙时期对伊比利亚半岛人口的差异性影响。 |
Carrion, P. |
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N/A |
Disparate demographic impacts of the Roman Colonization and the Migration Period in the Iberian Peninsula. |