| 内吞循环在昼夜节律性胶原蛋白纤维形成中起核心作用，并在纤维化过程中受到破坏。 |
CHANG, J. |
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N/A |
Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis |
| Rab10失活促进AMPAR插入和树突棘增大在长时程增强过程中 |
Wang, J. |
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Rab10 inactivation promotes AMPAR insertion and spine enlargement during long-term potentiation |
| 基于CRISPR-Cas的微同源介导的末端连接用于植物中精确基因替换 |
Vu, T. V. |
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N/A |
CRISPR-Cas-based Microhomology-Mediated End Joining for Precise Gene Replacement in Plant |
| 已撤回：拟南芥三羧酸循环中涉及的调控蛋白质的计算机分析及通过Alphafold和其他软件进行的结构分析 |
Nayab, H. |
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N/A |
WITHDRAWN: In-silico analysis of regulatory proteins involved in tricarboxylic acid cycle of Arabidopsis thaliana and structural analysis by Alphafold and other software |
| 热循环-高温下调了脂多糖诱导的人血炎症，并有助于清除单纯疱疹病毒1型 |
Kuo, Y.-Y. |
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N/A |
Thermal cycling-hyperthermia down-regulates liposaccharide-induced inflammation in human blood and helps with clearance of herpes simplex virus type 1 |
| 脑细胞外基质中的硫酸化糖胺聚糖取代了细胞外氯离子 |
Normoyle, K. P. |
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N/A |
Displacement of extracellular chloride by sulfated glycosaminoglycans of the brain extracellular matrix |
| 中度元基因组学：一种从环境样本中无需培养即可重建微生物基因组的新方法 |
Vollmers, J. |
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N/A |
Midi-metagenomics: A novel approach for cultivation independent microbial genome reconstruction from environmental samples |
| Hsf1-sHsp级联在蚊子细胞中具有广谱抗病毒活性 |
Qu, J. |
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N/A |
The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells |
| 鞭毛开关反向重复序列影响鞭毛的可逆性，并因梭状芽孢杆菌RT027/MLST1的毒力而异。 |
Nhu, N. T. Q. |
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N/A |
Flagellar switch inverted repeat impacts flagellar invertibility and varies Clostridioides difficile RT027/MLST1 virulence. |
| 对费氏弧菌中环二鸟苷酸调节蛋白的功能分析 |
Isenberg, R. Y. |
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N/A |
Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri |
| 突变顺序和上位性决定了FBXW7突变在结直肠癌进化中的后果 |
Chan, D. K. H. |
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Mutational order and epistasis determine the consequences of FBXW7 mutations during colorectal cancer evolution |
| 双路径架构使慢性压力能够破坏自主性并促进习惯的形成。 |
Giovanniello, J. R. |
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N/A |
A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation |
| 硅藻CO2固定器官的蛋白质蓝图 |
Nam, O. |
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N/A |
A Protein Blueprint of the Diatom CO2-Fixing Organelle |
| 在剪接泛基因组图上对选择性剪接事件进行差异定量 |
Ciccolella, S. |
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N/A |
Differential quantification of alternative splicing events on spliced pangenome graphs |
| 心脏交感和副交感指数的稳健且时间分辨的估计 |
Candia-Rivera, D. |
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N/A |
Robust and time-resolved estimation of cardiac sympathetic and parasympathetic indices |
| 水平转移的无细胞染色质颗粒在宿主细胞内作为自主捕食性基因组和转座元件的载体发挥作用。 |
Banerjee, S. |
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N/A |
Horizontally transferred cell-free chromatin particles function as autonomous predatory genomes and vehicles for transposable elements within host cells |
| RomX是一种新型原核调节因子，它将RomR的响应接收域与GTP结合的MglA连接起来，以建立Myxococcus xanthus的极性。 |
Chakraborty, S. |
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RomX, a novel prokaryotic regulator, links the response receiver domain of RomR with GTP-bound MglA for establishing Myxococcus xanthus polarity |
| 大声朗读与默读过程中信息权重的差异：基于fMRI数据表征相似性分析的证据 |
Bailey, L. M. |
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N/A |
Differential weighting of information during aloud and silent reading: Evidence from representational similarity analysis of fMRI data |
| CPT1A在结直肠癌中调节辐射敏感性 |
Chen, Z. |
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CPT1A Mediates Radiation Sensitivity in Colorectal Cancer |
| 盐诱导的根冠比自然变异揭示SR3G为拟南芥根栓化及盐韧性的负调控因子 |
Ishka, M. R. |
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Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis |
| 学习从快速手动点注释中精确分割神经纤维缠结 |
Ghandian, S. |
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N/A |
Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations |
| 在生长表面上超无序的细胞排列 |
Ross, R. J. H. |
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N/A |
Hyperdisordered cell packing on a growing surface |
| 利用基因组数据预测的气候适宜性比较加利福尼亚海峡群岛橡树（Quercus tomentella）的保护策略 |
Mead, A. |
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N/A |
Comparison of conservation strategies for California Channel Island Oak (Quercus tomentella) using climate suitability predicted from genomic data |
| 定义肺癌细胞对表观遗传抑制反应的异质分子图谱 |
Lin, C. |
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N/A |
Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition |
| 在铜绿假单胞菌临床分离株中，前噬菌体与抗生素耐药性的关联并不常见。 |
Chang, T. H. |
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N/A |
Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates |
| 在铜绿假单胞菌临床分离株中，前噬菌体与抗生素耐药性的关联并不常见。 |
Chang, T. H. |
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N/A |
Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates |
| 清洁死者：优化的去污方法提升更新世骨骼材料的古蛋白质组学分析效果 |
Fagernäs, Z. |
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N/A |
Cleaning the Dead: Optimized decontamination enhances palaeoproteomic analyses of Pleistocene skeletal material |
| 空间转录组学鉴定出新型铜绿假单胞菌毒力因子 |
Zhou, H. |
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N/A |
Spatial transcriptomics identifies novel Pseudomonas aeruginosa virulence factors |
| 遗传逻辑电路的能量感知技术映射 |
Kubaczka, E. |
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N/A |
Energy Aware Technology Mapping of Genetic Logic Circuits |
| 小鼠GnRH神经元在体内的多维振荡活动 |
Han, S. Y. |
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N/A |
Multi-dimensional oscillatory activity of mouse GnRH neurons in vivo |
| 斑马鱼HoxA和HoxD相关簇在胸鳍发育中的功能作用 |
Ishizaka, M. |
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N/A |
The functional roles of zebrafish HoxA- and HoxD-related clusters in the pectoral fin development |
| 质粒病毒维持能够使细菌种群从感染中恢复，并实现病毒与细菌的共存。 |
Sanchez-Martinez, R. |
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N/A |
Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence |
| 有毒的蓝光通过驱动肠道微生物介导的脂质积累，在果蝇中建立耐受性 |
Takada, Y. |
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N/A |
Toxic blue light drives the gut microbiota-mediated lipid accumulation to build tolerance in Drosophila |
| 功能成像和连接组分析揭示了果蝇味觉回路的组织原理 |
Li, J. |
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N/A |
Functional imaging and connectome analyses reveal organizing principles of taste circuits in Drosophila |
| 评估生理指标在通过比较问题测试（CQT）检测欺骗和诚实性中的应用 |
Rashid, A. M. S. |
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N/A |
Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT) |
| 评估生理指标在通过比较问题测试（CQT）检测欺骗和真实性中的应用 |
Rashid, A. M. S. |
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N/A |
Evaluating Physiological Indicators in Detecting Deception and Truthfulness using the Comparison Question Test (CQT) |
| 一种生理学启发的混合CPG/反射控制器，用于自行车模拟，并可推广至步行 |
Severini, G. |
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N/A |
A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking |
| 癌症-免疫共进化由抗原突变积累所决定 |
Wang, L. |
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N/A |
Cancer-immune coevolution dictated by antigenic mutation accumulation |
| 豆科植物共生基因的突变在多菌株接种过程中为根瘤菌的自然遗传变异创造了一个复杂的选择性环境。 |
Guha, S. |
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N/A |
Mutations in legume symbiosis genes create a complex selective landscape for natural genetic variation in rhizobia during multi-strain inoculations |
| AyurPhenoClusters 定义了罕见疾病的共同分子根源，并揭示了综合征条件下纤毛功能障碍。 |
Joshi, A. |
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N/A |
AyurPhenoClusters define common molecular roots for rare diseases and uncover ciliary dysfunctions in syndromic conditions |
| 灵长类新皮层中是否存在普遍的局部场电位功率频谱层状模式？ |
Mackey, C. A. |
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N/A |
Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex? |
| 通过基于CRISPR/Cas9 RNP的植物体内基因编辑技术培育出的长保质期甜瓜 |
Sasaki, K. |
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N/A |
A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing |
| 液滴测序揭示口腔生物膜外泌体中的毒力基因簇 |
Takano, S. |
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N/A |
Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles |
| GWA-X：一个可扩展的GPU加速包，用于全基因组关联研究中的排列检验 |
Agung, M. |
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N/A |
GWA-X: An Extensible GPU Accelerated Package for Permutation Testing in Genome-Wide Association Studies |
| 泛基因组启发的语言模型用于隐私保护的合成基因组序列生成 |
Huang, P. |
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N/A |
Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation |
| 海马体γCaMKII的多巴胺化促进突触到核的信号传递及记忆形成 |
Stewart, A. F. |
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N/A |
Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation |
| 外生菌根真菌松乳菇（Suillus luteus）在原生和引入种群中的生物合成基因簇多样性 |
Allen, B. M. |
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N/A |
Biosynthetic Gene Cluster Diversity Across Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus |
| GCK-MODY中独特的持续时间和饮食依赖性脂质谱及肾并发症 |
Huang, Y. |
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N/A |
Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY |
| 造血干细胞来源的脂肪细胞消融减少了同基因小鼠高级别浆液性癌模型中的肿瘤负荷 |
Woodruff, E. R. |
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N/A |
Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma |
| 利用光遗传学技术快速可逆地调控出芽酵母细胞周期的进展 |
Koutsoumpa, A. |
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N/A |
Rapid and reversible regulation of cell cycle progression in budding yeast using optogenetics |
| 胆碱能神经元活性通过毒蕈碱信号传导促进弥漫性中线胶质瘤的生长 |
Drexler, R. |
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N/A |
Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling |
| 膜相关传送带控制细菌第9型分泌系统的旋转方向 |
Trivedi, A. |
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N/A |
A membrane-associated conveyor belt controls the rotational direction of the bacterial type 9 secretion system |
| 量化生物研究中条形图的数据失真 |
Lin, T.-J. |
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N/A |
Quantifying Data Distortion in Bar Graphs in Biological Research |
| 人类肺部先天性和适应性免疫细胞的动态反应突显了哮喘风险位点基因的作用 |
Tian, F. |
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N/A |
Dynamic responses of human lung innate and adaptive immune cells highlight the roles of genes at asthma risk loci |
| 在受控的人类流感病毒感染后，先天免疫的表观基因组景观 |
Thistlethwaite, W. |
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N/A |
Innate immune epigenomic landscape following controlled human influenza virus infection |
| 加尔瓦宁是一种用于定向细胞迁移的电场传感器。 |
Belliveau, N. M. |
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N/A |
Galvanin is an electric-field sensor for directed cell migration |
| 果蝇发育翅膀中立方上皮向扁平上皮转变的机械调控 |
Harmansa, S. |
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N/A |
Mechanical regulation of cuboidal-to-squamous epithelial transition in the Drosophila developing wing |
| Elavl1对于附肢骨骼发育并非必需。 |
Parsha, R. |
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N/A |
Elavl1 is dispensable for appendicular skeletal development |
| PAEP、KRT10和BMP7基因SNPs与克莱猪繁殖性状的关联分析 |
Zhao, Y. |
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N/A |
Association analysis of PAEP, KRT10 and BMP7 Genes SNPs with reproductive traits in Kele pigs |
| 保护基因组研究中的隐私：作者全面框架 |
Ghasemian, M. |
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N/A |
Safeguarding Privacy in Genome Research: A Comprehensive Framework for Authors |
| 基于网络药理学、分子对接及细胞实验探讨滋癸益冲方减轻卵巢早衰中卵泡颗粒细胞凋亡的机制 |
Zhang, X. |
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N/A |
Explore the mechanism of Zigui Yichong Formula in reducing the apoptosis of ovarian granulosa cells in premature ovarian insufficiency based on network pharmacology, molecular docking and cell experiments |
| 构建儿童科学绘画的规范：基于大语言模型语义相似性的分布特征 |
Zhang, Y. |
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N/A |
Constructing a Norm for Children's Scientific Drawing: Distribution Features Based on Semantic Similarity of Large Language Models |
| 探究视觉素养技能揭示了学生对染色体尺度与抽象概念的理解。 |
Uminski, C. |
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N/A |
Probing visual literacy skills reveals student conceptions of scale and abstraction with respect to chromosomes |
| 丙酮酸的命运通过调节细胞的氧化还原电位来决定细胞的生长。 |
Toshniwal, A. G. |
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N/A |
The fate of pyruvate dictates cell growth by modulating cellular redox potential |
| 表面递送定量揭示了成簇的protocadherin异构体之间不同的运输效率 |
May, E. J. |
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N/A |
Surface delivery quantification reveals distinct trafficking efficiencies among clustered protocadherin isoforms |
| 振动幅度在红眼树蛙胚胎逃逸孵化反应中的作用 |
Jung, J. |
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N/A |
The role of vibration amplitude in the escape hatching response of red-eyed treefrog embryos |
| erm-1的本地化翻译有助于ERM-1在秀丽隐杆线虫胚胎中的功能 |
Salm, E. v. d. |
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N/A |
Localized translation of erm-1 contributes to ERM-1 function in the C. elegans embryo |
| 高WEE1表达与多发性骨髓瘤患者的不良生存率独立相关。 |
Simhal, A. K. |
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N/A |
High WEE1 expression is independently linked to poor survival in multiple myeloma |
| 早期阿尔茨海默病中突触密度与代谢型谷氨酸受体之间关系的评估：一项多示踪剂PET研究 |
Salardini, E. |
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N/A |
Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer's disease: a multi-tracer PET study |
| 发酵底物的分解代谢性质影响无氧生长下大肠杆菌的蛋白质组重构 |
Momin, H. |
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N/A |
The catabolic nature of fermentative substrates influence proteomic rewiring in Escherichia coli under anoxic growth |
| 通过表征VGLUT1mEos2敲低的新型小鼠模型，揭示了VGLUT1表达水平对量子大小的一个微小影响。 |
Zhang, X. M. |
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N/A |
A minor impact of VGLUT1 expression level on quantal size revealed through the characterization of VGLUT1mEos2 knock-down new mouse model |
| 脊髓损伤引起的脑部炎症和认知能力下降可以通过脊髓细胞移植得到逆转。 |
Delarue, Q. |
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N/A |
Brain inflammation and cognitive decline induced by spinal cord injury can be reversed by spinal cord cell transplants |
| 小鼠上丘视觉表征的扫视调制神经基质 |
Hunt, J. |
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N/A |
Neural substrates for saccadic modulation of visual representations in mouse superior colliculus |
| 绿色合成氧化铁/石墨烯磁性纳米复合材料作为新型抗菌材料的制备 |
Kazazi, M. |
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N/A |
Production of green synthesized iron oxide/graphene magnetic nanocomposite as a novel antibacterial material |
| 环境泥炭藓相关真菌通过靶向硫醇稳态与结核分枝杆菌竞争。 |
Malhotra, N. |
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N/A |
Environmental sphagnum-associated fungi target thiol homeostasis to compete with Mycobacterium tuberculosis. |
| 利用背腹侧亨廷顿病类器官和亨廷顿病小鼠胚胎鉴定幼年亨廷顿病细胞群体的神经发育组织 |
Switonska-Kurkowska, K. |
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N/A |
Identification of neurodevelopmental organization of the cell populations of juvenile Huntington's disease using dorso-ventral HD organoids and HD mouse embryos |
| 埃及伊蚊中肠提取物的全面蛋白水解分析：揭示血液餐蛋白消化系统 |
O'Donoghue, A. J. |
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N/A |
Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system |
| 胎儿特异性基因LIN28B对人类胎儿B淋巴细胞生成至关重要，并参与KMT2A::AFF1婴儿白血病的启动。 |
Ling, R. E. |
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N/A |
The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia |
| H9c2分化的优化导致无需添加视黄酸即可形成钙活性及横纹肌心脏细胞。 |
Brock, J. |
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N/A |
Optimization of H9c2 differentiation leads to calcium-active and striated cardiac cells without addition of retinoic acid. |
| habtools：一个用于计算表面和物体三维指标的R包 |
Schiettekatte, N. M. |
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N/A |
habtools: an R package to calculate 3D metrics for surfaces and objects |
| 一种用于检测陆地动物环境DNA的地面表面滚动方法 |
Kakita, M. |
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N/A |
A ground surface rolling method for detecting environmental DNA of terrestrial animals |
| 在考虑父亲精子储存的情况下，没有证据表明父亲的年龄对儿子或女儿有影响。 |
Sanghvi, K. |
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N/A |
No evidence for paternal age effects on sons or daughters, when accounting for paternal sperm storage |
| 野外采集的伊蚊中自然存在的沃尔巴克氏菌的全球流行率：一项系统综述和荟萃分析 |
Gebremariam, T. T. |
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N/A |
Global prevalence of naturally occurring Wolbachia in field-collected Aedes mosquitoes: a systematic review and meta-analysis |
| 与心血管疾病相关的非编码变异破坏了GATA4-DNA结合及其调控功能 |
Pena-Martinez, E. G. |
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N/A |
Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions |
| 原位通用正交网络（UNION）生物墨水沉积技术用于直接输送角膜基质干细胞至角膜伤口 |
Brunel, L. G. |
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N/A |
In Situ UNIversal Orthogonal Network (UNION) Bioink Deposition for Direct Delivery of Corneal Stromal Stem Cells to Corneal Wounds |
| 将3D打印机用作绘图仪，为进行二维迁移分析开辟了一个全新的领域。 |
Köppe, H. |
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N/A |
The use of 3D-printers as plotters opens up a new world in performing 2D migration analyses |
| 假马齿苋植物化学物质作为阿尔茨海默病治疗中有前景的BACE1抑制剂 |
Sangeet, S. |
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N/A |
Bacopa monnieri phytochemicals as promising BACE1 inhibitors for Alzheimers Disease Therapy |
| 对于脊椎动物胚胎发育而言，基因表达谱的PCA（主成分分析）解释性不如慷慨性。 |
Ogata, N. |
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N/A |
Liberality is More Explainable than PCA of Transcriptome for Vertebrate Embryo Development |
| IκBζ的组成性表达促进黑色素瘤的生长并导致免疫疗法抵抗 |
Kolb, A. |
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N/A |
Constitutive expression of IκBζ promotes tumor growth and immunotherapy resistance in melanoma |
| 使用DARPin选择性靶向TBXT可识别脊索瘤中的调控网络和治疗脆弱性 |
Umbaugh, C. S. |
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N/A |
Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma |
| miR-21：一种在高脂饮食小鼠中延缓重度肝病和肝细胞癌的治疗靶点 |
Jagtap, U. |
PDF |
N/A |
miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice |
| Rho/MRTF抑制诱导的黑色素瘤细胞凋亡事件及其对药物耐药性的预防机制探讨：涉及pirin的潜在作用 |
Foda, B. |
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N/A |
Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: Implications for the involvement of pirin |
| C57BL/6J小鼠在家庭笼中的乙醇饮用和操作性自我给药中的性别差异，但由谷氨酸AMPAR活性进行的调节是等效的。 |
Faccidomo, S. |
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N/A |
Sex Differences in Home-Cage Ethanol Drinking and Operant Self-Administration in C57BL/6J Mice but Equivalent Regulation by Glutamate AMPAR Activity |
| 在阿尔茨海默病3xTg小鼠模型中，许多热量限制的好处需要禁食才能实现。 |
Babygirija, R. |
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N/A |
Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer&aposs disease |
| 不同浓度吲哚乙酸（IAA）对不同李（Prunus domestica L.）栽培品种形态特征的响应 |
Ullah, K. |
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N/A |
Response of Various Concentrations of Indole Acetic Acid (IAA) to Morphological Attributes in Different Plum (Prunus domestica L.) Curltivars |
| 肝脏中一种矛盾的肿瘤抗原特异性反应 |
Trehan, R. S. |
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N/A |
A Paradoxical Tumor Antigen Specific Response in the Liver |
| 用于评估恒河猴支气管肺泡灌洗液中白细胞的细胞和功能表型的42参数质谱流式细胞术面板 |
Makatsa, M. S. |
PDF |
N/A |
42-parameter mass cytometry panel to assess cellular and functional phenotypes of leukocytes in bronchoalveolar lavage of Rhesus macaque |
| 可变大小群体中一般家谱的TMRCA |
Wemces, A. H. |
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N/A |
The TMRCA of general genealogies in populations of variable size |
| 下一代雪豹种群评估工具：用于从粪便中个体识别的多重PCR SNP面板 |
Solari, K. A. |
PDF |
N/A |
Next-generation snow leopard population assessment tool: multiplex-PCR SNP panel for individual identification from feces |
| 桥本甲状腺炎背景下甲状腺乳头状癌的蛋白质组学分析 |
Zhou, H. |
PDF |
N/A |
Proteomic analysis of papillary thyroid carcinoma in the context of Hashimoto's thyroiditis |
| 学习增强型草图绘制技术在保护隐私和安全的基因组关联分析（GWAS）中提供了改进的性能。 |
Xu, J. |
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N/A |
Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS |
| 结构解析：脯氨酸富集区域在Tau功能中的作用 |
Acosta, K. |
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N/A |
Structural Insights into the Role of the Proline Rich Region in Tau Function |
| 基于机器学习的癌症及转移中整合素表达模式研究 |
Shadman, H. |
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N/A |
A Machine Learning-Based Investigation of Integrin Expression Patterns in Cancer and Metastasis |
| 在衰老的狒狒中，前额叶皮层线粒体生物能量学的性别特异性下降与行走速度相关 |
Adekunbi, D. A. |
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N/A |
Sex-specific decline in prefrontal cortex mitochondrial bioenergetics in aging baboons correlates with walking speed |
| 成纤维细胞的空间编程通过排除免疫细胞促进组织炎症的消退 |
Reis Nisa, P. |
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N/A |
Spatial programming of fibroblasts promotes resolution of tissue inflammation through immune cell exclusion |
| MDA5 ISGylation 对免疫信号传导至关重要，可调控病毒复制和发病机制 |
Sarkar, L. |
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N/A |
MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis |
| 胞外cGAMP及其类似物对T细胞的毒性是由于SLC7A1介导的导入所致。 |
Sudaryo, V. |
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N/A |
Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import |
| 独立的鸟类表观遗传时钟用于衰老和发育 |
Haller, A. |
PDF |
N/A |
Independent avian epigenetic clocks for aging and development |
| 切尔诺贝利啮齿动物中代谢率与放射性剂量率的协变关系 |
Boratynski, Z. |
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N/A |
Covariation between metabolic and radioactive dose rates in Chornobyl rodents |
| 森林转化为农业用地降低了我国西南岩溶石漠化地区土壤黑碳组分含量。 |
Zhang, D. |
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N/A |
The conversion of forests to agricultural land reduced the content of soil black carbon fractions in a karst rocky desertification area of Southwest China |
| 拟除虫菊酯类杀虫剂是否会影响敏捷蛙（Rana dalmatina）的性别比例？ |
Balogh, E. |
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N/A |
Do pyrethroid insecticides influence sex ratios in agile frogs (Rana dalmatina)? |
| 热带森林中相邻生境的真菌群落时空动态和组装过程存在差异 |
Lin, C.-P. |
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N/A |
Spatiotemporal dynamics and assembly process differ in fungal communities across contiguous habitats in tropical forests |
| 蚜虫宿主转换的触发因素及决定机制解析 |
Etier, A. |
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N/A |
Insights into the triggering factors and determination mechanisms of host alternation in aphids |
| 有限种群结构但存在近期选择信号：引入北美洲的非洲无花果蝇（Zaprionus indianus） |
Erickson, P. A. |
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N/A |
Limited population structure but signals of recent selection in introduced African Fig Fly (Zaprionus indianus) in North America |
| 南美慈鲷鳍骨的可塑性受觅食方式改变的影响 |
Gilbert, M. |
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N/A |
Plasticity in the pectoral fin skeleton is induced by altered foraging regime in a South American cichlid |
| 建立一个全球地下动物条形码参考库 |
Guzik, M. T. |
PDF |
N/A |
Towards a global barcode reference library for subterranean fauna |
| 同义突变和单核苷酸变化有助于水平转移基因的适应性。 |
Venkataraman, P. |
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N/A |
Synonymous and single nucleotide changes facilitate the adaptation of a horizontally transferred gene. |
| 古老的倒位多态性在一种广泛分布的蝴蝶物种中具有局部适应性。 |
Seixas, F. A. |
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N/A |
Ancient inversion polymorphisms are locally adaptive in a widespread butterfly species |
| 性状依赖的生物地理学为梅桂（番荔枝科）在澳大拉西亚-太平洋地区的扩散提供了见解 |
Liu, M.-F. |
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N/A |
Trait-dependent biogeography offers insights on the dispersal of Meiogyne (Annonaceae) across the Australasia-Pacific region |
| 在按蚊细胞中进行的全基因组CRISPR筛选鉴定了必需基因和氯膦酸盐脂质体功能所需的成分 |
Mameli, E. |
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N/A |
A genome-wide CRISPR screen in Anopheles mosquito cells identifies essential genes and required components of clodronate liposome function |
| 种系丢失减少了体细胞线粒体，但在衰老和低温过程中保留了呼吸功能。 |
Hwang, H. |
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N/A |
Germline loss diminishes somatic mitochondria but confers preservation of respiratory function during aging and hypothermia |
| 生物银行规模和分布式数据集中SNP遗传力的分析和计算解决方案 |
Qi, G.-A. |
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N/A |
Analytical and computational solution for the estimation of SNP-heritability in biobank-scale and distributed datasets |
| 精心挑选的转录组数据集，用于研究病毒呼吸道接种和疫苗接种后血液和鼻样本的转录反应 |
Lan, Z. |
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N/A |
A curated collection of transcriptome datasets to study the transcriptional response in blood and nasal samples following viral respiratory inoculation and vaccination |
| 高拷贝数子宫内膜癌中超倍体基因型的功能影响 |
Florio, A. |
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N/A |
Functional impact of the hyperduplication genomophenotype in high copy number endometrial cancer |
| 从头组装和注释飞虱线粒体基因组 |
Molligan, J. |
PDF |
N/A |
De novo assembly and annotation of the Empoasca fabae mitochondrial genome |
| 从斑点到细胞：使用BOMS在空间转录组学中进行细胞分割 |
Kamboj, O. |
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N/A |
From spots to cells: Cell segmentation in spatial transcriptomics with BOMS |
| 面对不断变化的海域，关键沿海生物扰动者Hediste diversicolor的分子武器库 |
Beine, K. |
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N/A |
The molecular arsenal of the key coastal bioturbator Hediste diversicolor faced with changing oceans |
| 机器学习优化的选择性剪接靶向检测 |
Yang, K. |
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N/A |
Machine learning-optimized targeted detection of alternative splicing |
| 转座元件在自然界中普遍作为跨代表观遗传继承的载体 |
Baduel, P. |
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N/A |
Transposable elements are prevalent vectors of transgenerational epigenetic inheritance in nature |
| 在严格一夫多妻制的木蚁物种中，超级基因的丧失 |
Sigeman, H. |
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N/A |
The loss of a supergene in obligately polygynous Formica wood ant species |
| 已建立的硫肽串联质谱行为和硫酸转移酶测定法否定了酪氨酸硫酸化作为组蛋白标记的可能性 |
Youssef, M. M. |
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N/A |
Established Sulfopeptide Tandem Mass Spectrometry Behavior and Sulfotransferase Assays Refute Tyrosine Sulfation as a Histone Mark |
| 直接且超灵敏的生物发光检测完整呼吸道病毒 |
Grawe, A. |
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N/A |
Direct and ultrasensitive bioluminescent detection of intact respiratory viruses |
| AlphaFold3在抗体和纳米抗体对接方面学到了什么，还有哪些问题尚未解决？ |
Hitawala, F. N. |
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N/A |
What has AlphaFold3 learned about antibody and nanobody docking, and what remains unsolved? |
| snCED-seq：用于FFPE组织单核RNA测序的高保真冷冻酶解离核技术 |
yunxia, G. |
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N/A |
snCED-seq: High-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues |
| 通过海洋甲烷氧化菌-微藻共培养生产依克多因，实现了生物气的完全价值化。 |
Ruiz-Ruiz, P. |
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N/A |
Ectoine production through a marine methanotroph-microalgae culture allows complete biogas valorization |
| 细菌谱系中脯氨酰寡肽酶及相关序列的鉴定与研究 |
Nayak, S. D. |
PDF |
N/A |
Identification and study of Prolyl Oligopeptidases and related sequences in bacterial lineages |
| 通过结合与对称性相关的分子来提高姿态预测的准确性 |
Vijayan, D. |
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N/A |
Improving the accuracy of pose prediction by incorporating symmetry-related molecules |
| 子宫内膜异位症中焦亡相关基因的鉴定与诊断潜力：一项新颖的生物信息学分析 |
Teng, P. |
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N/A |
Identification and Diagnostic Potential of Pyroptosis-Related Genes in Endometriosis: A Novel Bioinformatics Analysis |
| 通过综合计算机方法鉴定隐孢子虫肌苷5'-单磷酸脱氢酶的潜在抑制剂 |
Al-Mamun, A. |
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N/A |
Identification of potential inhibitors against Inosine 5'-Monophosphate Dehydrogenase of Cryptosporidium parvum through an integrated in silico approach |
| 在单细胞RNA测序中，利用scPCA联合建模细胞异质性和条件效应 |
Vohringer, H. S. |
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N/A |
Joint Modeling of Cellular Heterogeneity and Condition Effects with scPCA in Single-Cell RNA-Seq |
| 设计具有所需熔化温度的热稳定蛋白质 |
Tijare, P. |
PDF |
N/A |
Designing of thermostable proteins with a desired melting temperature |
| 探索中肠表达动力学：成年雌性美洲钝眼蜱中肠的纵向转录组分析及与其他硬蜱物种的比较见解 |
Lu, S. |
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N/A |
Exploring midgut expression dynamics: longitudinal transcriptomic analysis of adult female Amblyomma americanum midgut and comparative insights with other hard tick species |
| 解码蛋白质动力学：ProFlex作为正常模式分析中的语言桥梁 |
Magill, D. |
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N/A |
Decoding Protein Dynamics: ProFlex as a Linguistic Bridge in Normal Mode Analysis |
| 代谢建模揭示了拟南芥热生长反应的决定因素 |
Wendering, P. |
PDF |
N/A |
Metabolic modeling identifies determinants of thermal growth responses in Arabidopsis thaliana |
| MolAR：用Rust编写的MD模拟分析内存安全库 |
Yesylevskyy, S. |
PDF |
N/A |
MolAR: memory-safe library for analysis of MD simulations written in Rust |
| 基于Martini的酶粗粒化模型的框架：模型开发与实验验证 |
Hooten, M. |
PDF |
N/A |
Framework for Martini-based Coarse-grained Model of Enzymes: Model Development and Experimental Validation |
| 老化大鼠模型中与认知相关的蛋白质结构变化与减少的重折叠能力有关 |
Tarbox, H. E. |
PDF |
N/A |
Cognition-Associated Protein Structural Changes in a Rat Model of Aging are Related to Reduced Refolding Capacity |
| 纤维蛋白凝块的介观模拟：凝胶点处流变学与微观结构的相互作用 |
Zohravi, E. |
PDF |
N/A |
Mesoscale Modelling of Fibrin Clots: The Interplay between Rheology and Microstructure at the Gel Point |
| 流动状态下二元混合物中的主动分离 |
Di Dio, G. |
PDF |
N/A |
Active segregation in binary mixtures under flow |
| 一种开放量子系统方法用于Bicoid梯度动力学 |
Lone, I. |
PDF |
N/A |
An Open Quantum System Approach to Bicoid Gradient Dynamics |
| ATP合酶亚基e（ATP5I）在介导双胍类药物的代谢和抗增殖效应中的作用 |
Lefrancois, G. |
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N/A |
The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Biguanides |
| 食管腺癌与正常邻近组织间蛋白质表达的比较分析 |
Nicholas, B. |
PDF |
N/A |
Comparative analysis of protein expression between oesophageal adenocarcinoma and normal adjacent tissue |
| 北美野生河狸（Castor canadensis）的尸检结果揭示了对加利福尼亚淡水生态系统的潜在威胁 |
Gonzales-Viera, O. A. |
PDF |
N/A |
Postmortem findings of free-ranging North American beavers (Castor canadensis) reveal potential threats to California freshwater ecosystems |
| 通过疾病相关微生物群重新审视葡萄藤酸腐病：三重共感染？ |
Hevin, S. |
PDF |
N/A |
Revisiting sour rot of grapevine through disease-associated microbiomes: a tripartite co-infection? |
| 通过行为分析进行毒性测试，观察有机溶剂对秀丽隐杆线虫的普遍和特定不良影响 |
Tomioka, M. |
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N/A |
Observation of general and specific adverse effects of organic solvents on Caenorhabditis elegans by toxicity testing using behavioral analysis |
| 刺激调制稳态法：事件相关功能磁共振成像的新范式。 |
Mathew, R. |
PDF |
N/A |
Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI. |
| 肿瘤诱导的内皮细胞RhoA激活介导肿瘤细胞跨内皮迁移和转移 |
Sajib, M. S. |
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N/A |
Tumor-induced endothelial RhoA activation mediates tumor cell transendothelial migration and metastasis |
| 在Cyp17a1敲除大鼠中，从内脏脂肪向皮下脂肪的转变阻止了代谢综合征的进展 |
Jeon, B.-J. |
PDF |
N/A |
Shift from visceral to subcutaneous fat in Cyp17a1 knockout rats prevent the progression of metabolic syndrome |
| ALMS1 KO大鼠：一种具有自发性高血压的新型代谢综合征模型 |
Jaykumar, A. B. |
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N/A |
ALMS1 KO rat: a new model of metabolic syndrome with spontaneous hypertension |
| 小鼠在二氧化碳挑战下的血管反应 |
Yang, X. |
PDF |
N/A |
Vascular responses of hypercapnia challenge in mice |
| 高光谱成像在遥感山毛榉树皮病初期方面能力有限。 |
Tougas, G. |
PDF |
N/A |
Hyperspectral imaging has a limited ability to remotely sense the onset of beech bark disease |
| 高阶和分布式协同功能相互作用在目标导向学习中编码信息增益 |
Combrisson, E. |
PDF |
N/A |
Higher-order and distributed synergistic functional interactions encode information gain in goal-directed learning |
| 人类和小鼠神经元皮层可分离性的内在特征识别 |
Yun, Z. |
PDF |
N/A |
Identification of Intrinsic Features for Cortical Separability of Human and Mouse Neurons |
| 前额叶皮层中视觉运动神经元的贝叶斯推理 |
Langlois, T. |
PDF |
N/A |
Bayesian inference by visuomotor neurons in prefrontal cortex |
| 永久性噪音引起的听力损失后的听觉决策缺陷 |
Berns, M. P. |
PDF |
N/A |
Auditory decision-making deficits after permanent noise-induced hearing loss |
| 先天失明个体腹侧视觉流中对物体镜像的重复抑制，而非对盲文字母的重复抑制 |
Korczyk, M. |
PDF |
N/A |
Repetition suppression for mirror images of objects and not Braille letters in the ventral visual stream of congenitally blind individuals |
| 多效营养因子缺失可预防高脂饮食引起的认知功能障碍、神经胶质反应及海马区周围神经网的变化。 |
Caneque-Rufo, H. |
PDF |
N/A |
Pleiotrophin deletion prevents high-fat diet-induced cognitive impairment, glial responses, and alterations of the perineuronal nets in the hippocampus |
| 低强度脉冲超声波激活培养的海马神经元中的兴奋性突触网络 |
Li, F. |
PDF |
N/A |
Low intensity pulsed ultrasound activates excitatory synaptic networks in cultured hippocampal neurons |
| 体感皮层与身体表征：在视觉-本体感觉线索冲突期间更新运动系统 |
Mirdamadi, J. L. |
PDF |
N/A |
Somatosensory cortex and body representation: Updating the motor system during a visuo-proprioceptive cue conflict |
| BDNF增强逆转了颅脑放射治疗引起的认知功能下降和神经退行性后果 |
El-Khatib, S. M. |
PDF |
N/A |
BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences |
| 神经网络结构如何改变大脑的自组织临界性 |
Sugimoto, Y. A. |
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N/A |
How neural network structure alters the brain's self-organized criticality |
| 不同类别的抗抑郁药物通常会改变小鼠苍白球的结构和功能 |
Abe, Y. |
PDF |
N/A |
Distinct classes of antidepressants commonly act to shape pallidal structure and function in mice |
| 被盗的未来：异常的海马神经发生导致癫痫中产生胶质细胞 |
Segasby, T. |
PDF |
N/A |
A stolen future: aberrant hippocampal neurogenesis produces glial cells in epilepsy |
| 缺失但未受糖皮质激素调节的促肾上腺皮质激素释放激素（Crh）调控小鼠的焦虑样行为 |
Friedman, H. R. |
PDF |
N/A |
Absent, but not glucocorticoid-modulated, corticotropin-releasing hormone (Crh) regulates anxiety-like behaviors in mice |
| 用于消融兴奋性和抑制性突触的工具箱 |
Bareghamyan, A. |
PDF |
N/A |
A toolbox for ablating excitatory and inhibitory synapses |
| 在活体细胞内成像显示，癫痫发作后皮质扩散性去极化期间，内质网钙离子出现耗竭。 |
Stern, M. A. |
PDF |
N/A |
Organellular imaging in vivo reveals a depletion of endoplasmic reticular calcium during post-ictal cortical spreading depolarization |
| 高速三维成像与25相机多焦点显微镜 |
Hirata-Miyasaki, E. |
PDF |
N/A |
High-speed 3D Imaging with 25-Camera Multifocus Microscope |
| 年龄对静息状态下皮层网络的影响 |
Gohil, C. |
PDF |
N/A |
Effects of age on resting-state cortical networks |
| 评估白尾鹿（Odocoileus virginianus）中蜱唾液和中肠细胞外囊泡作为抗蜱疫苗的效果 |
Gonzalez Gonzalez, J. |
PDF |
N/A |
Evaluation of tick salivary and midgut extracellular vesicles as anti-tick vaccines in White-tailed deer (Odocoileus virginianus) |
| 鼻内接种CPAF联合环二腺苷酸可诱导记忆性CD4 T细胞反应，并在经阴道感染鼠衣原体后减轻细菌负荷 |
Poston, T. B. |
PDF |
N/A |
Intranasal immunization with CPAF combined with cyclic-di-AMP induces a memory CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum |
| 感知到的压力会加重人体皮肤中的银屑病：来自人源化银屑病小鼠模型的见解 |
Zeltzer, A. |
PDF |
N/A |
Perceived stress exacerbates psoriasis in human skin in vivo: Insights from a humanized psoriasis mouse model |
| 啮齿动物PD1的进化指纹使其活性减弱，但增强了对肿瘤的免疫力，相较于人类PD1。 |
Masubuchi, T. |
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N/A |
Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1 |
| 鉴定出一种关键的INO2等位基因，可增强工业发酵酵母菌株Saccharomyces cerevisiae的乙醇抗性 |
Albillos-Arenal, S. |
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N/A |
Identification of a crucial INO2 allele for enhancing ethanol resistance in an industrial fermentation strain of Saccharomyces cerevisiae |
| 志贺氏菌通过IpaH1.4介导的RNF213降解逃避LPS泛素化 |
Naydenova, K. |
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N/A |
Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213 |
| 选择性保留北大西洋海洋中的岩藻糖丰富低聚糖 |
Bligh, M. |
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N/A |
Selective preservation of fucose-rich oligosaccharides in the North Atlantic Ocean |
| 时空、环境和行为因素对管理蜜蜂蜂群中瓦螨密度的预测作用 |
Boehm Vock, L. |
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N/A |
Spatiotemporal, environmental, and behavioral predictors of Varroa mite intensity in managed honey bee apiaries |
| 传粉者访问模式和差异性繁殖相容性维持了印度西高止山脉一种夜间开花的姜科植物的苞片颜色多态性 |
Shrotri, S. |
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N/A |
Pollinator visitation pattern and differential reproductive compatibilities maintain bract colour polymorphism in a nocturnal ginger from Western Ghats, India |
| 在孟加拉国亚热带季风气候下的半农村地区，果蝇（双翅目：实蝇科）的种群动态 |
Momen, M. |
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N/A |
Population dynamics of fruit flies (Diptera: Tephritidae) in a semirural area under subtropical monsoon climate of Bangladesh |
| 海洋碳输出可以通过基于海洋颜色的浮游植物群落来预测。 |
Kramer, S. J. |
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N/A |
Ocean carbon export can be predicted from ocean color-based phytoplankton communities |
| 蜂后餐桌上的农民？：蜜蜂（Apis mellifera）在准备蜂群过程中微生物群的动态变化 |
Kolasa, M. R. |
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N/A |
Peasants at the queen's table?: The microbiome's dynamics throughout swarming preparation in honey bees (Apis mellifera) |
| 季节性和年际稳定性在胶状绒紫菜（红藻门）种群遗传结构中的表现 |
Shainker-Connelly, S. J. |
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N/A |
Seasonality and inter-annual stability in the population genetic structure of Batrachospermum gelatinosum (Rhodophyta) |
| 细胞色素P450的自然变异独立于β-微管蛋白，改变了噻菌灵的反应。 |
Collins, J. |
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N/A |
Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independent of beta-tubulin |
| 利用单细胞eQTL分析鉴定导致代谢功能障碍相关脂肪性肝炎的个体水平变异基因 |
Hong, S. E. |
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N/A |
Identification of genes conferring individual-level variation responsible for metabolic dysfunction-associated steatohepatitis using single-cell eQTL analysis |
| 高阶上位性在大规模蛋白质序列-功能关系中的重要性 |
Sethi, P. |
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N/A |
Importance of higher-order epistasis in large protein sequence-function relationships |
| 单细胞多组学分析揭示了胚胎发育过程中转录与染色质相互作用的原则 |
Bhardwaj, V. |
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N/A |
Single-cell multi-omic analysis reveals principles of transcription-chromatin interaction during embryogenesis |
| 补充膳食纳米锌可通过调节铜锌超氧化物歧化酶表达来赋予更高的抗氧化状态 |
Tah, A. |
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N/A |
Supplemental Dietary Nano Zinc Can Impart Higher Antioxidant Status by Modulating Cu-Zn SOD Expression |
| 细胞收缩力驱动四维生物打印活体构建物的时空形态变化 |
Cleveland, D. S. |
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N/A |
Cell Contractile Forces Drive Spatiotemporal Morphing in 4D Bioprinted Living Constructs |
| 去细胞化细胞外基质（dECM）及其衍生墨水的成分的比较蛋白质组学分析与天然组织相比 |
Irastorza, A. |
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N/A |
Comparative proteomic analysis of the composition of decellularized extracellular matrix (dECM) and dECM-based inks as compared to the native tissue |
| 基于柔性石墨烯的神经技术用于帕金森病大鼠的高精度深脑映射和神经调控 |
Ria, N. |
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N/A |
Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats |
| 探索使用贝塔过程先验对贝叶斯生存分析中的基线危险进行灵活惩罚 |
Dauda, K. A. |
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N/A |
Exploring the Flexible Penalization of Bayesian Survival Analysis Using Beta Process Prior for Baseline Hazard |
| 实现单细胞声学定位与去激活超分辨率 |
Smith, C. A. B. |
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N/A |
Achieving Single Cell Acoustic Localisation with Deactivation Super Resolution |
| PhysiofUS：一种基于组织运动的心率和呼吸率评估方法，用于神经功能超声成像 |
ZUCKER, N. |
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N/A |
PhysiofUS : a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging |
| 通过生物树脂分子量调节和多波长光学技术实现的多材料体积生物打印与即插即用悬浮浴生物制造 |
Ribezzi, D. |
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N/A |
Multi-material volumetric bioprinting and plug-and-play suspension bath biofabrication via bioresin molecular weight tuning and multiwavelength optics |
| 超越静态脑图谱：基于人工智能的开放数据库构建与全脑神经形态学动态挖掘 |
Jiang, S. |
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N/A |
Beyond Static Brain Atlases: AI-Powered Open Databasing and Dynamic Mining of Brain-Wide Neuron Morphometry |
| AlphaMut：一种用于建议螺旋破坏性突变的深度强化学习模型 |
Bhargav, P. |
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N/A |
AlphaMut: a deep reinforcement learning model to suggest helix-disrupting mutations |
| 使用高光谱图像和机器学习对虾青素含量进行准确的无创定量 |
Calderini, M. |
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N/A |
Accurate non-invasive quantification of astaxanthin content using hyperspectral images and machine learning |
| 构建面向透明生物医学人工智能的文献知识库 |
Huang, Y. |
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N/A |
Building a literature knowledge base towards transparent biomedical AI |
| AsaruSim：单细胞与空间RNA-Seq纳米孔长读长模拟工作流程 |
Hamraoui, A. |
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N/A |
AsaruSim: a single-cell and spatial RNA-Seq Nanopore long-reads simulation workflow |
| 磷酸化调控的无序核受体的构象多样性与拓扑动力学 |
Akulov, V. |
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N/A |
Phosphorylation regulated conformational diversity and topological dynamics of an intrinsically disordered nuclear receptor |
| RNA G-四链体中肌苷、2'-O-甲基化和N6-甲基腺苷修饰的结构和动态后果：一项分子动力学研究 |
Dutta, N. |
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N/A |
Structural and dynamic consequences of inosine, 2'-O-methylation, and N6-methyladenosine modifications in RNA G-quadruplex: A molecular dynamics study |
| 甲基-CpG结合域蛋白维持表观遗传的机制模型 |
Dai, L. |
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N/A |
Mechanistic model for epigenetic maintenance by methyl-CpG-binding domain proteins |
| 线粒体泛素连接酶MARCHF5与MCL1合作抑制KSHV转化的原发性渗出性淋巴瘤细胞系的凋亡 |
Viswanathan, P. |
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N/A |
The Mitochondrial Ubiquitin Ligase MARCHF5 Cooperates with MCL1 to Inhibit Apoptosis in KSHV-Transformed Primary Effusion Lymphoma Cell Lines |
| 超级增强子分析揭示了ThPOK/ZBTB7B，一种CD4+细胞谱系承诺因子，作为主调控因子，限制乳腺癌细胞呈现管腔非迁移表型。 |
Arcuschin, C. D. |
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N/A |
Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype |
| MAX失活会扰乱MYC网络，并在多种组织中诱导神经内分泌肿瘤的形成。 |
Freie, B. |
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N/A |
MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues |
| 肺腺癌对顺铂和培美曲塞化疗耐药现象中Orai3通道和ABC型转运蛋白的特征及意义。 |
Daoudi, R. |
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N/A |
Characterization and implication of the Orai3 channel and ABC type transporters in the phenomenon of chemoresistance to cisplatin and pemetrexed in lung cancer. |
| 头颈部癌症中纳米气泡超声造影剂的异质动力学与血管生成信号传导 |
Van Court, B. |
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N/A |
Heterogeneous Kinetics of Nanobubble Ultrasound Contrast Agent and Angiogenic Signaling in Head and Neck Cancer |
| 血小板中密集但不包含α颗粒的成分对于胰腺β细胞分泌胰岛素是必需的。 |
Kolczynska-Matysiak, K. |
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N/A |
Dense but not alpha granules of platelets are required for insulin secretion from pancreatic beta cells |
| 评估SUBI和DRO1渗入系在不同生长阶段下对淹水和干旱条件的耐受性 |
Soe, I. |
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N/A |
Assessing Stress Tolerance of SUBI and DRO1 Introgression lines Under Flooding and Drought Conditions at Different Growth Stages |
| 过氧化物酶2介导了人类骨骼肌肌管中由收缩活动诱导的氧化磷酸化过程中对氧化还原刺激的适应性变化。 |
Heaton, R. A. |
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N/A |
Peroxiredoxin 2 mediates redox-stimulated adaptations to oxidative phosphorylation induced by contractile activity in human skeletal muscle myotubes |
| 多器官转录组图谱揭示了分娩的特征 |
Ni, D. |
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N/A |
Multi-organ transcriptomic atlas reveals hallmarks of labor |
| 四吡咯生物合成酶的自然变异及其调控机制改变了叶绿素突变体Oy1-N1989的特性。 |
Kaur, A. |
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N/A |
Natural variation in tetrapyrrole biosynthetic enzymes and their regulation modify the chlorophyll mutant Oy1-N1989 |
| 对七种开花植物中选择性剪接、长链非编码RNA和环状RNA的综合注释 |
Gabel, A. |
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N/A |
Comprehensive annotations of alternative splicing, lncRNAs, and circRNAs in seven species of flowering plants |
| 从基因到通路：一种精选基因方法在硬骨鱼转录组学中准确重建通路的应用 |
Herrera, M. |
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N/A |
From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics |
| DrugTar通过整合大型语言模型和基因本体论，提升了药物预测能力。 |
Borhani, N. |
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N/A |
DrugTar Improves Druggability Prediction by Integrating Large Language Models and Gene Ontologies |
| 鸡蛋辐照对野生型和沃尔巴克氏体转染的埃及伊蚊蚊媒发育和致育性的影响 |
Kittayapong, P. |
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N/A |
Effect of egg irradiation on development and sterility of wild-type and Wolbachia trans-infected Aedes aegypti mosquito vectors |
| 运动准备在时间决策中追踪决策边界交叉 |
Ofir, N. |
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N/A |
Motor preparation tracks decision boundary crossing in temporal decision-making |
| 淀粉样β蛋白诱导的培养星形胶质细胞中快速局部钙升高的改变 |
Nakata, K. |
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N/A |
Amyloid-β-induced Alteration of Fast and Localized Calcium Elevations in Cultured Astrocytes |
| 为什么我们有这么多兴奋性神经元？ |
Wang, Q. |
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N/A |
Why do we have so many excitatory neurons? |
| CX3CR1 调节常驻小胶质细胞向脑损伤部位的迁移 |
Wagner, J. |
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N/A |
CX3CR1 modulates migration of resident microglia towards brain injury |
| 内源性大麻素2-花生四烯酰甘油通过细胞外微泡按需释放和运输 |
Straub, V. M. |
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N/A |
The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles |
| 阿尔茨海默病小鼠模型中CA1和CA3区位细胞功能的明显紊乱 |
Park, S. |
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N/A |
Distinct Disruptions in CA1 and CA3 Place Cell Function in Alzheimer's Disease Mice |
| 在自由活动的小鼠进行探索行为期间，胡须体感皮层的具身处理 |
Gantar, L. |
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N/A |
Embodied processing in whisker somatosensory cortex during exploratory behaviour in freely moving mice |
| 触须剥夺引发了一种特殊的皮层稳态可塑性，但在Fmr1 KO中这种可塑性受损。 |
Lakhani, A. |
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N/A |
Whisker deprivation triggers a distinct form of cortical homeostatic plasticity that is impaired in the Fmr1 KO |
| 白细胞介素37抗炎复合物的计算建模 |
Sardag, I. |
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N/A |
Computational Modeling of the Anti-Inflammatory Complexes of IL37 |
| A2.CAR Treg与抗CD154联合治疗在小鼠同种异体不匹配心脏移植模型中的疗效及局限性 |
Durgam, S. S. |
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N/A |
Efficacy and limitations of combined A2.CAR Treg and anti-CD154 therapy in a mouse model of haplo-mismatched heart transplantation |
| 母体免疫保护后代免受肠道病毒感染，同时不会对体液免疫记忆产生负面影响。 |
Muleta, K. G. |
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N/A |
Maternal immunity protects offspring from enteric viral infection without negatively affecting humoral immune memory |
| 利用内质网滞留信号工程化CD3亚基促进异基因CAR T细胞生产 |
Ebrahimiyan, H. |
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N/A |
Engineering CD3 Subunits with Endoplasmic Reticulum Retention Signal Facilitates Allogeneic CAR T Cell Production |
| BiMultiNetPlot：一个用于可视化生态二分多层网络的R包 |
Li, H.-D. |
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N/A |
BiMultiNetPlot: An R package for visualizing ecological bipartite multilayer networks |
| 小型哺乳动物及其洞穴塑造了球孢子菌在土壤中的分布：一项长期的生态实验 |
Head, J. R. |
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N/A |
Small mammals and their burrows shape the distribution of Coccidioides in soils: a long-term ecological experiment |
| 趋异选择和可塑性在物种形成初期塑造了生殖隔离 |
Jarrett, B. J. M. |
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N/A |
Divergent selection and plasticity shape reproductive isolation at the onset of speciation |
| 饮食特化推动了雁形目（Anseriformes）在头骨和附肢骨骼上的适应、趋同和整合。 |
Chatterji, R. M. |
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N/A |
Dietary specialization drives adaptation, convergence, and integration across the cranial and appendicular skeleton in Waterfowl (Anseriformes). |
| 古代生物分子表明已灭绝的洞熊具有学习觅食策略 |
Meleg, I. N. |
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N/A |
Ancient biomolecules suggest learned foraging strategy in extinct cave bears |
| 在野生酵母模型中非整倍体回复的速率 |
Gasch, A. P. |
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N/A |
On the rate of aneuploidy reversion in a wild yeast model |
| 全球土壤传播蠕虫的多样性揭示了影响诊断目标的群体偏向性遗传变异 |
Papaiakovou, M. |
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N/A |
Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets |
| Rfam 15：2025年的RNA家族数据库 |
Ontiveros-Palacios, N. |
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N/A |
Rfam 15: RNA families database in 2025 |
| 大规模突变扫描和深度学习的转录抑制域预测与设计 |
Valbuena, R. |
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N/A |
Prediction and design of transcriptional repressor domains with large-scale mutational scans and deep learning |
| 巴巴利猕猴社交信息的化学特征 |
Weiss, B. M. |
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N/A |
Chemical signatures of social information in Barbary macaques |
| 可操控的弹簧带针用于在组织中自主急转弯 |
Abdoun, O. |
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N/A |
Steerable Tape-Spring Needle for Autonomous Sharp Turns Through Tissue |
| STANCE：一种统一的统计模型，用于在空间转录组学中检测细胞类型特异的空间变异基因 |
Su, H. |
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N/A |
STANCE: a unified statistical model to detect cell-type-specific spatially variable genes in spatial transcriptomics |
| 基于OPLS的多类分类与数据驱动的类间关系发现 |
Forsgren, E. |
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N/A |
OPLS-based Multiclass Classification and Data-Driven Inter-Class Relationship Discovery |
| 药物化学中的AI增强R基团探索 |
Zhao, H. |
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N/A |
AI-Augmented R-Group Exploration in Medicinal Chemistry |
| 隐神经刺激对两种不同膀胱状态（活动不足和活动过度）的兴奋和抑制作用 |
li, C. |
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N/A |
Excitatory and Inhibitory Effects of Saphenous Nerve Stimulation on Two Different Bladder Conditons: Underactivity and Overactivity |
| 睡眠期间心率变异性受损：REM睡眠行为障碍、创伤性脑损伤及创伤后应激障碍退伍军人中自主神经功能障碍的早期潜在窗口？ |
Cunningham, H. A. |
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N/A |
Heart rate variability impairment during sleep in Veterans with REM sleep behavior disorder, traumatic brain injury, and posttraumatic stress disorder: An early potential window into autonomic dysfunction? |
| 健康数据科学教育洞察：定性内容分析 |
Rohani, N. |
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N/A |
Insights into Health Data Science Education: A Qualitative Content Analysis |
| 人类溶质载体超家族的代谢图谱 |
Wiedmer, T. |
PDF |
N/A |
Metabolic mapping of the human solute carrier superfamily |
| 需要腿部顺应性来解释不同步态中的地面反作用力模式和速度范围。 |
Safa, A. T. |
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N/A |
Leg compliance is required to explain the ground reaction force patterns and speed ranges in different gaits |
| 人类听觉皮层中的时间整合主要与绝对时间相关，而非结构持续时间。 |
Norman-Haignere, S. V. |
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N/A |
Temporal integration in human auditory cortex is predominantly yoked to absolute time, not structure duration |
| Na+/K+-ATPase的生电性给高度活跃的尖峰细胞的计算带来了挑战。 |
Weerdmeester, L. |
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N/A |
The electrogenicity of the Na+/K+-ATPase poses challenges for computation in highly active spiking cells |
| 心脏对听觉不规则性的反应揭示了睡眠期间的分层信息处理 |
Koroma, M. |
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N/A |
Cardiac responses to auditory irregularities reveal hierarchical information processing during sleep |
| microRNA-138-5p在小脑输入层抑制兴奋性突触强度 |
Delvendahl, I. |
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N/A |
microRNA-138-5p suppresses excitatory synaptic strength at the cerebellar input layer |
| TMX1是一种二硫键氧化还原酶，通过调节CD3zeta对T细胞功能至关重要。 |
Chai, T. |
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N/A |
TMX1, a disulfide oxidoreductase, is necessary for T cell function through regulation of CD3zeta |
| CXCL16-CXCR6的进化多样性：爬行动物中的趋同替代和反复基因丢失 |
Salve, B. G. |
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N/A |
Evolutionary diversity of CXCL16-CXCR6: Convergent Substitutions and Recurrent Gene Loss in Sauropsids |
| EGO-1和RRF-1在调控秀丽隐杆线虫生殖系外源RNAi效率中的双重作用 |
Dejima, K. |
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N/A |
Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans |
| 一个支持法国淡水环境中水生大型无脊椎动物DNA条形码分析的注释参考库 |
Gauvin, P. |
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N/A |
An annotated reference library for supporting DNA metabarcoding analysis of aquatic macroinvertebrates in French freshwater environments |
| 对111个鲽形目线粒体基因组的全面分析：结构、保守性、变异及进化的见解 |
Tan, S. |
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N/A |
Comprehensive analysis of 111 Pleuronectiformes mitochondrial genomes: insights into structure, conservation, variation and evolution |
| 利用长读长测序和基因组组装鉴定出Aspergillus wentii的萜类合成酶武器库 |
Olumakaiye, R. |
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N/A |
Identification of a terpene synthase arsenal using long-read sequencing and genome assembly of Aspergillus wentii |
| 人类长非编码RNA的基因组生物学：虚拟核型 |
Palma, A. |
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N/A |
Genome biology of long non-coding RNAs in humans: a virtual karyotype |
| Jaeger：一种准确且快速的深度学习工具，用于检测噬菌体序列 |
Wijesekara, Y. |
PDF |
N/A |
Jaeger: an accurate and fast deep-learning tool to detect bacteriophage sequences |
| 通过厚组织的空间转录组学在空间和时间上解卷积器官发生 |
Asami, S. |
PDF |
N/A |
Deconvolving organogenesis in space and time via spatial transcriptomics in thick tissues |
| 哺乳动物启动子具有RNA聚合酶II低占用率和高周转率的特点。 |
Chatsirisupachai, K. |
PDF |
N/A |
Mammalian promoters are characterised by low occupancy and high turnover of RNA polymerase II |
| 双歧杆菌假链状菌的胶囊性胞外多糖增强了临床前乳腺癌中的全身抗肿瘤免疫 |
Price, C. A. |
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Bifidobacterium pseudocatenulatum capsular exopolysaccharide enhances systemic anti-tumour immunity in pre-clinical breast cancer |
| 同时分析克罗恩病和有症状对照组的血液和肠道T细胞和B细胞库，揭示了克罗恩病患者免疫库的组织特异性改变 |
Mahdy, A. K. H. |
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Simultaneous Profiling of the Blood and Gut T and B Cell Repertoires in Crohn's Disease and Symptomatic Controls Illustrates Tissue-specific Alterations in the Immune Repertoire of Crohn's Disease Patients |
| 偷听食草动物：使用接触式麦克风量化植物-昆虫相互作用 |
Mehrotra, D. |
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Eavesdropping on Herbivores: Using contact microphones to quantify Plant-Insect Interactions |
| 绘制与小麦病原菌Zymoseptoria tritici温度胁迫相关的基因组区域图谱 |
Stapley, J. |
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Mapping genomic regions associated with temperature stress in the wheat pathogen Zymoseptoria tritici |
| BRCA1、BRCA2和PALB2变异分类中共同分离分析的综合且易获取模型 |
Moghadasi, S. |
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A Comprehensive and Accessible Model for Co-Segregation Analysis in BRCA1, BRCA2, and PALB2 Variant Classification |
| dScaff - 一个基于参考基因组数据，用于自动搭建从头组装草图的生物信息学框架 |
Constantin, N. D. |
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dScaff - an automatic bioinformatics framework for scaffolding draft de novo assemblies based on reference genome data |
| 艺术X的相机路径、建模及图像处理工具 |
Ermel, U. H. |
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Camera Paths, Modeling, and Image Processing Tools for ArtiaX |
| 肝细胞中线粒体复合体III功能的恢复突显了肝脏作为独立于棕色脂肪细胞激活的关键产热器官的作用。 |
Banerjee, R. |
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Restoration of mitochondrial complex III function in hepatocytes highlights the liver as a key thermogenic organ independent of brown adipocyte activation |
| 探索记忆性景观：双曲几何揭示物体概念记忆中的层次结构 |
Lee, F. M. |
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Navigating Memorability Landscapes: Hyperbolic Geometry Reveals Hierarchical Structures in Object Concept Memory |
| 来自ADHD诱导的多能干细胞（iPSC）模型的多巴胺能神经元的转录组分析 |
Namipashaki, A. |
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Transcriptome profiling of dopaminergic neurons derived from an ADHD induced pluripotent stem cell (iPSC) model |
| 评估秘鲁塔克纳地区土壤中潜在有毒元素及其由环境责任引发的潜在生态风险 |
Caceda Quiroz, C. J. |
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Evaluation of Potentially Toxic Elements in Soil and Potential Ecological Risks Generated by Environmental Liabilities in Tacna, Peru |
| 对用于人口控制的自我限制遗传控制策略的比较评估 |
Han, Y. |
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A comparative assessment of self-limiting genetic control strategies for population suppression |
| 通过基于针的腔扩张方法捕获的生物材料演化特性 |
Varner, H. M. |
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Evolving properties of biological materials captured via needle-based cavity expansion method |
| 模仿机制：肉类与肉类替代品的比较 |
St. Pierre, S. R. |
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Mimicking mechanics: A comparison of meat and meat analogs |
| 高通量实证与虚拟筛选发现乳腺癌中多倍体巨型癌细胞的新型抑制剂 |
Ma, Y. |
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High-Throughput Empirical and Virtual Screening to Discover Novel Inhibitors of Polyploid Giant Cancer Cells in Breast Cancer |
| 具有独立调控粘附配体迁移率和粘弹性的水凝胶可增强细胞粘附和扩展 |
Moghaddam, A. S. |
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Hydrogels with Independently Controlled Adhesion Ligand Mobility and Viscoelasticity Increase Cell Adhesion and Spreading |
| 通过氧化苯酚偶联在细胞上共价结合生物材料，通过细胞内生物物理编程调节干细胞命运 |
Johnbosco, C. |
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Covalent on-cell conjugation of biomaterials through oxidative phenolic coupling regulates stem cell fate via intracellular biophysical programming |
| scParadise：可调节的高精度多任务细胞类型注释与表面蛋白丰度预测 |
Chechekhina, E. |
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scParadise: Tunable highly accurate multi-task cell type annotation and surface protein abundance prediction |
| 残留物替代对蛋白质细胞丰度的影响 |
Schulze, T. K. |
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Effects of residue substitutions on the cellular abundance of proteins |
| 核小体定位和聚合物力学解释了100千碱基尺度的基因组接触 |
Corrette, J. |
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Nucleosome placement and polymer mechanics explain genomic contacts on 100kbp scales |
| 丙戊酸对髓母细胞瘤中干细胞和分化调节因子的调控 |
Freire, N. H. |
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Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma |
| 破表者：基于微孔阵列的微型胸腺类器官模型的建立，适用于高通量应用。 |
Major, V. |
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Watch-breaker: establishment of a microwell array-based miniaturized thymic organoid model suitable for high throughput applications. |
| 通过在三维培养中使用倾向神经转录因子刺激人类视网膜的再生能力 |
Wohlschlegel, J. |
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Stimulating the regenerative capacity of the human retina with proneural transcription factors in 3D cultures |
| 空间结构对崎岖适应性景观中早期和长期适应的影响 |
Servajean, R. |
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Impact of spatial structure on early and long-term adaptation in rugged fitness landscapes |
| 斑胸草雀距离呼叫声学特征的依赖于情境的调制：来自一种新颖的目标导向发声范式的见解 |
Safarcharati, Z. |
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Context-Dependent Modulations in Acoustic Features of Zebra Finch Distance Calls: Insights from a Novel Goal-Directed Vocalization Paradigm |
| 斑马鱼视锥视蛋白光谱位移的分子机制 |
Chi, L. A. |
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Molecular Mechanisms Underlying the Spectral Shift in Zebrafish Cone Opsins |
| 在多稳态知觉过程中，观察者会经历哪些感知类别？ |
Skerswetat, J. |
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Which perceptual categories do observers experience during multistable perception? |
| 通过DynamicNeuronTracker揭示了单个化学感觉神经元对外部刺激的小鼠组织切片组合反应性 |
Noh, J. |
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Combinatorial responsiveness of single chemosensory neurons to external stimulation of mouse explants revealed by DynamicNeuronTracker |
| Akap11 突变小鼠（一种精神分裂症和双相情感障碍的遗传模型）中，突触PKA活性升高以及纹状体多巴胺信号传导异常。 |
Song, B. J. |
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Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder |
| 人背根神经节中端细胞的转录组学和组织学特征 |
Haberberger, R. V. |
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Transcriptomic and histological characterization of telocytes in the human dorsal root ganglion |
| 睡眠剥夺小鼠大脑皮层细胞特异性转录组和核蛋白组的整合分析 |
Jha, P. K. |
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An integrative analysis of cell-specific transcriptomics and nuclear proteomics of sleep-deprived mouse cerebral cortex |
| 从诱导多能干细胞发展而来的内皮向造血转变的发育调控 |
Wellington, R. |
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Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells |
| 动态转录和表观遗传变化定义了出生后肌腱的生长 |
Dingwall, H. L. |
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Dynamic transcriptional and epigenetic changes define postnatal tendon growth |
| 动态BMP信号调节斑马鱼中生骨节的诱导和谱系多样化 |
Xie, L. |
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Dynamic BMP signaling regulates sclerotome induction and lineage diversification in zebrafish |
| 一种优化用于生长和发育的果蝇全营养饮食 |
Sorge, S. |
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A Drosophila holidic diet optimised for growthand development |
| Api-TRACE：一种用于在受限环境中追踪蜜蜂的系统，旨在研究蜜蜂学习过程及锂对学习的影响 |
Erdem, B. |
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Api-TRACE: A System for Honey Bee Tracking in a Constrained Environment to Study Bee Learning Process and the Effect of Lithium on Learning |
| 语音解码能力与左侧弓状束的纤维密度在阅读发展的纵向过程中存在关联。 |
Perdue, M. V. |
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Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development |
| 脂肪细胞代谢状态调节胶质细胞吞噬功能 |
Rajan, A. |
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Adipocyte metabolic state regulates glial phagocytic function |
| 在一种可调控TDP-43的小鼠模型中，超兴奋性先于CA3海马神经退行性变，该模型模拟了ALS-FTD（肌萎缩侧索硬化-额颞叶痴呆）。 |
Rodemer, W. |
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Hyperexcitability precedes CA3 hippocampal neurodegeneration in a dox-regulatable TDP-43 mouse model of ALS-FTD. |
| BrainScale：在脉冲神经网络中实现可扩展的在线学习 |
Wang, C. |
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BrainScale: Enabling Scalable Online Learning in Spiking Neural Networks |
| Pdgfab/Pdgfra介导的趋化作用引导了来自肌节衍生的成纤维细胞前体在斑马鱼中的迁移 |
Mendez-Olivos, E. E. |
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Pdgfab/Pdgfra-mediated chemoattraction guides the migration of sclerotome-derived fibroblast precursors in zebrafish |