| 协调口手食物操作的皮层回路 |
An, X. |
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N/A |
A cortical circuit for orchestrating oromanual food manipulation |
| 针对β冠状病毒的嵌合免疫原的结构预测，以诱导靶向抗体 |
Simpson, J. |
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N/A |
Structural prediction of chimeric immunogens to elicit targeted antibodies against betacoronaviruses |
| 利用分布式光学传感器自动化昆虫生物多样性指标：在美国堪萨斯州农业系统中的评估 |
Rydhmer, K. |
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N/A |
Automating an insect biodiversity metric using distributed optical sensors: an evaluation across Kansas, USA cropping systems |
| 一个标准化、在线交付、临床适用的神经认知评估平台：WebNeuro |
Williams, L. M. |
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N/A |
A platform for standardized, online delivered, clinically applicable neurocognitive assessment: WebNeuro |
| SIMVI揭示了空间组学数据中的内在状态和空间诱导状态 |
Dong, M. |
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N/A |
SIMVI reveals intrinsic and spatial-induced states in spatial omics data |
| 有丝分裂染色质标记控制DNA损伤的不对称分离 |
Ferrand, J. |
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N/A |
Mitotic chromatin marking governs asymmetric segregation of DNA damage |
| 人类骨骼肌纤维异质性超越肌球蛋白重链 |
Moreno-Justicia, R. |
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N/A |
Human skeletal muscle fiber heterogeneity beyond myosin heavy chains |
| NeuroMechFly v2，模拟成年果蝇的具身感觉运动控制 |
Wang-Chen, S. |
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N/A |
NeuroMechFly v2, simulating embodied sensorimotor control in adult Drosophila |
| 解释老年人舌尖现象：大脑功能、结构和灌注对老年人心肺健康的影响 |
Rahman, F. |
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N/A |
Explaining tip-of-the-tongue experiences in older adults: contributions of brain function, structure, and perfusion in relation to older adults cardiorespiratory fitness |
| 果蝇幼虫肠道中病原菌的高效清除需要Duox/TrpA1/Dh31和IMD途径的空间和时间协调。 |
Tleiss, F. |
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N/A |
Spatial and temporal coordination of Duox/TrpA1/Dh31 and IMD pathways is required for the efficient elimination of pathogenic bacteria in the intestine of Drosophila larvae |
| CD44 在空气介导的细胞间信号传导中促进粘附相互作用。 |
Bowman, R. L. |
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N/A |
CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling |
| 视听音乐会表演能够同步观众的心率。 |
Czepiel, A. M. |
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N/A |
Audio-visual concert performances synchronize an audience's heart rates |
| 微眼跳选择性作为对象解码的判别特征 |
Nouri, S. |
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N/A |
Microsaccade Selectivity as Discriminative Feature for Object Decoding |
| 硫酸乙酰肝素结合调控HpARI蛋白家族在体内的半衰期 |
Colomb, F. |
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N/A |
Heparan sulphate binding controls in vivo half-life of the HpARI protein family |
| 哺乳动物腹侧苍白球在单细胞分辨率下的转录组图谱 |
Yang, L. |
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N/A |
Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution |
| 在稀疏数据中对排名列表富集评分进行分析，揭示了算法的权衡 |
Wenzel, A. T. |
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N/A |
Profiling ranked list enrichment scoring in sparse data elucidates algorithmic tradeoffs |
| 毛首鞭形线虫未知的系统发育定位、全基因组组装及基因组范围关联研究：一种引起鞭虫病的新型人感染物种，对阿苯达唑-伊维菌素敏感性较低 |
Baer, M. A. |
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N/A |
Phylogenetic placement, whole genome assembly, and genome-wide association study of Trichuris incognita: a novel human-infecting species causing trichuriasis, with low sensitivity to albendazole-ivermectin |
| 具有保形保证的功能蛋白质挖掘 |
Boger, R. S. |
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N/A |
Functional protein mining with conformal guarantees |
| 沙尘暴驱动的潜在病原体和抗生素抗性基因在东地中海地区的扩散 |
Erkorkmaz, B. A. |
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N/A |
Dust storm-driven dispersal of potential pathogens and antibiotic resistance genes in the Eastern Mediterranean |
| DNA甲基化分析工具中Infinium MethylationEPIC v2.0与v1.0读数差异的影响及对人类群体表观遗传学研究的考量 |
Zhuang, B. C. |
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N/A |
Discrepancies in readouts between Infinium MethylationEPIC v2.0 and v1.0 reflected in DNA methylation-based tools: implications and considerations for human population epigenetic studies |
| 在启动子和增强子内的成簇κB位点之间的协同作用决定了NF-κB RelA的转录特异性，同时还有特定的共因子参与。 |
Shahabi, S. |
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N/A |
Cooperativity among clustered κB sites within promoters and enhancers dictates transcriptional specificity of NF-κB RelA along with specific cofactors |
| 一种能够穿越血脑屏障的神经肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了具有抗惊厥、神经保护和抗炎特性的药理性低体温。 |
Ferhat, L. |
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N/A |
A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice |
| 急性全身照射对胸腺上皮细胞的第二次影响 |
Namiki, K. |
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N/A |
Second impact of an acute total body irradiation on thymic epithelial cells |
| 掌握神经影像分析中的伪影校正：回顾性方法 |
Oliveira, A. |
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N/A |
Mastering Artifact Correction in Neuroimaging Analysis: A Retrospective Approach |
| 内源性逆转录病毒位点及在日本本土鸡中诱导的基因表达变化 |
Ishihara, S. |
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N/A |
Endogenous Retrovirus Loci and Induced Changes in Gene Expression in Japanese Indigenous Chickens |
| 丰富的活跃社区成员响应温泉光合垫的昼夜周期 |
Shelton, A. N. |
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N/A |
Abundant and active community members respond to the diel cycle in hot spring phototrophic mats |
| 楚科奇海环斑海豹和髯海豹的丰度和分布：未来趋势的参考 |
Boveng, P. L. |
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N/A |
Abundance and distribution of ringed and bearded seals in the Chukchi Sea: a reference for future trends |
| 整合酶复合体亚基12敲除克服了逆转HIV潜伏性的转录阻滞 |
Gray, C. N. |
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N/A |
Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal |
| 像姐妹而非双胞胎——加压素和催产素通过细胞类型特异性表达的催产素受体激活BNST神经元，从而减少焦虑性觉醒。 |
Francesconi, W. |
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N/A |
Like sisters but not twins - vasopressin and oxytocin excite BNST neurons via cell type-specific expression of oxytocin receptor to reduce anxious arousal |
| 在心脏形成过程中，心包膜作为一个独立的结构形成。 |
Moran, H. R. |
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N/A |
The pericardium forms as a distinct structure during heart formation |
| 在加利福尼亚中部城市环境中越冬的穴居猫头鹰（Athene cunicularia hypugaea）到达较晚，离开较早，偏好有遮蔽的微生境，能够忍受雨水，并与多种捕食者竞争。 |
Nicolaus, M. A. |
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N/A |
Athene cunicularia hypugaea wintering in a central California urban setting arrive later, leave earlier, prefer sheltered micro-habitat, tolerate rain, and contend with diverse predators |
| 视网膜母细胞瘤蛋白（Rb）口袋结构域中与癌症相关的错义变异的结构和功能分析 |
Castro, A. |
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N/A |
Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain |
| 瞬态Notch激活促使多能干细胞衍生的心肌细胞向浦肯野纤维命运转变 |
Gonzalez, D. M. |
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N/A |
Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate |
| 一种用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱仪系统 |
bazargan, s. |
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N/A |
A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets |
| 解码mEos4b的日间成熟过程及工程化快速成熟变体 |
Maity, A. |
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N/A |
Decoding mEos4b Day-Long Maturation and Engineering Fast Maturing Variants |
| 缺血损伤后猪肾脏在常温机械灌注保存结束时，尽管功能未变，但代谢重编程并诱导移植后纤维化：来自肾脏蛋白质组的见解。 |
Mulvey, J. F. |
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N/A |
End of preservation normothermic machine perfusion of porcine kidneys after ischaemic injury reprograms metabolism and induces fibrosis after transplant despite unchanged function: insights from the renal proteome. |
| 系统发育基因组学和代谢工程揭示茄科植物中存在一个保守的甾体生物合成基因簇 |
Hakim, S. E. |
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N/A |
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis |
| 组织驻留记忆CD4+ T细胞的维持依赖于特定部位的自我更新水平以及来自前体的补充。 |
Chandler, J. |
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N/A |
Tissue resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and replacement from precursors |
| 通过味觉受体检测细菌可启动细胞免疫反应 |
Mazariegos, A. N. |
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N/A |
Detection of bacteria through taste receptors primes the cellular immune response |
| 活体秀丽隐杆线虫的器官特异性亲电应答图谱绘制 |
Liu, J. |
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N/A |
Organ-specific electrophile responsivity mappingin live C. elegans |
| 基于细胞的检测技术评分SARS-CoV-2核衣壳蛋白药物诱导凝聚的比较评估 |
Quek, R. T. |
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N/A |
Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein |
| 通过电子断层扫描技术对核糖体数量进行原位定量 |
El Hankouri, M. |
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N/A |
In situ quantification of ribosome number by electron tomography |
| 不同保护制度对西高止山脉木本植物多样性和组成的影响 |
Shigwan, B. K. |
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N/A |
Effect of differential protection regimes on the diversity and composition of woody plants in the Western Ghats |
| 描述与真菌病原体球孢子菌（Coccidioides immitis）相关的土壤微生物群落 |
Radosevich, M. T. |
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N/A |
Characterizing the soil microbial community associated with the fungal pathogen Coccidioides immitis |
| 陆地食草动物通过间接效应推动水生群落的适应性进化 |
Schaefer, M. |
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N/A |
Terrestrial herbivory drives adaptive evolution in an aquatic community via indirect effects |
| 四种酵母物种及其杂交种在极端温度条件下的长期进化潜力 |
Pinto, J. |
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N/A |
The long-term evolutionary potential of four yeast species and their hybrids in extreme temperature conditions |
| 反复的基因渐渗和地理分层塑造了新热带地区的酿酒酵母 |
Avelar-Rivas, J. A. |
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N/A |
Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics |
| 通过纳米孔长读长测序技术分析天然CpG甲基化，精细定位调控变异 |
Tian, Y. |
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N/A |
Fine Mapping Regulatory Variants by Characterizing Native CpG Methylation with Nanopore Long Read Sequencing |
| 核型I肌球蛋白对生命和基因组组织至关重要 |
Peng, A. Y. T. |
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N/A |
Nuclear Type I Myosins are Essential for Life and Genome Organization |
| Integral-Omics：利用活检组织进行连续提取与代谢组、脂质组、基因组、转录组、全蛋白质组及磷酸化蛋白质组的分析与表征 |
Li, W. |
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N/A |
Integral-Omics: serial extraction and profiling of metabolome, lipidome, genome, transcriptome, whole proteome and phosphoproteome using biopsy tissue |
| 使用ROS/RNS条件蛋白质组学分析参与过氧亚硝酸盐稳态的蛋白质 |
Zhu, H. |
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N/A |
Profiling proteins involved in peroxynitrite homeostasis using ROS/RNS conditional proteomics |
| 生成机器学习用于ADAR底物的精准高效RNA编辑 |
Jiang, Y. |
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N/A |
Generative machine learning of ADAR substrates for precise and efficient RNA editing |
| 统一采样与排序用于蛋白质对接的DFMDock方法 |
Chu, L.-S. |
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N/A |
Unified Sampling and Ranking for Protein Docking with DFMDock |
| CAMDA 2023：在城市微生物群中寻找模式 |
Contreras-Peruyero, H. |
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N/A |
CAMDA 2023: finding patterns in urban microbiomes |
| ConoDL：一种用于快速生成和预测芋螺毒素的深度学习框架 |
Guo, M. |
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N/A |
ConoDL: A Deep Learning Framework for Rapid Generation and Prediction of Conotoxins |
| 通过动力学蒙特卡罗模拟合理化蛋白质-蛋白质相互作用在靶向蛋白质降解中的功能角色 |
Su, Z. |
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N/A |
Rationalize the Functional Roles of Protein-Protein Interactions in Targeted Protein Degradation by Kinetic Monte-Carlo Simulations |
| 肿瘤细胞空间组织通过YAP信号传导指导EGFR/RAS/RAF通路主要治疗抵抗 |
Nakagawa, R. |
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N/A |
Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling |
| 抑制FOXM1与BCL2抑制剂Venetoclax协同作用，通过抑制MYC通路杀死非t(11;14)多发性骨髓瘤细胞。 |
Wen, Z. |
PDF |
N/A |
Inhibition of FOXM1 synergizes with BCL2 inhibitor Venetoclax in killing non-t(11;14) multiple myeloma cells via repressing MYC pathway |
| MKK4和MKK7在青光眼相关损伤后控制视网膜神经节细胞体和轴突的退化。 |
Marola, O. J. |
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N/A |
MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury. |
| ERFVIIs在陆地植物对低氧胁迫响应的进化过程中扮演着氧气感知传感器的角色 |
Dalle Carbonare, L. |
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N/A |
The role of ERFVIIs as oxygen-sensing transducers in the evolution of land plant response to hypoxia |
| 小麦NLR蛋白PM3b定位于内质网-质膜接触位点，并通过其LRR结构域与AVRPM3b2/c2相互作用。 |
Isaksson, J. |
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N/A |
The wheat NLR protein PM3b localizes to endoplasmic reticulum-plasma membrane contact sites and interacts with AVRPM3b2/c2 through its LRR domain. |
| 植物移动域蛋白-DNA基序模块通过对抗Polycomb沉默来稳定基因表达 |
Pelissier, T. |
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N/A |
Plant Mobile Domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression |
| 转录记忆介导硫化物胁迫响应的可塑性，以促进单带海神鳗的适应性 |
Zhang, W. |
PDF |
N/A |
Transcriptional memories mediate the plasticity of sulfide stress responses to enable acclimation in Urechis unicinctus |
| 一种新型小鼠模型展示了在急性消融成功后中枢神经系统周细胞的在体补充 |
Atak, D. |
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N/A |
A Novel Mouse Model Demonstrates In Vivo Replenishment of Central Nervous System Pericytes After Successful Acute Ablation |
| 生长抑素中间神经元选择初始学习阶段背内侧纹状体的表征 |
Rotariu, S. |
PDF |
N/A |
Somatostatin interneurons select dorsomedial striatal representations of the initial learning phase |
| HEXIM1与阿尔茨海默病病理相关，并调控神经元中即刻早期基因的动态变化。 |
Htet, M. |
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N/A |
HEXIM1 is correlated with Alzheimer's disease pathology and regulates immediate early gene dynamics in neurons |
| 利用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层特定区域边界图 |
Autio, J. A. |
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N/A |
Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI |
| 在患者来源的小鼠模型中，绘制疱疹病毒驱动对卡波西肉瘤细胞微环境和转录组特征的影响 |
Li, X. |
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N/A |
Mapping herpesvirus-driven impacts on the cellular milieu and transcriptional profile of Kaposi sarcoma in patient-derived mouse models |
| 跨完整浮游植物开花周期的微生物宏基因组：在22天内每4小时进行一次高分辨率采样 |
Nunn, B. L. |
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N/A |
Microbial Metagenomes Across a Complete Phytoplankton Bloom Cycle:High-Resolution Sampling Every 4 Hours Over 22 Days |
| 从朋友到敌人，再回到朋友——共生-对抗连续体中的协同进化转变 |
Jäger, F. |
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N/A |
From friend to foe and back - Coevolutionary transitions in the mutualism-antagonism continuum |
| 基因组揭示了禽类吸血蝇（Philornis downsi）在加拉帕戈斯群岛成功入侵的奥秘 |
Basnet, A. |
PDF |
N/A |
Genomic insights into the successful invasion of the avian vampire fly (Philornis downsi) in the Galapagos Islands |
| 代谢物对人糖酵解异构酶的弱调节作用：一项筛选研究 |
Jonatansdottir, Y. Y. |
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N/A |
Weak Modulation of Human Glycolysis Isomerases by Metabolites: A Screening Study |
| MetaLab平台支持全面的DDA和DIA元蛋白质组学分析 |
Cheng, K. |
PDF |
N/A |
MetaLab Platform Enables Comprehensive DDA and DIA Metaproteomics Analysis |
| 异二硫化物还原酶A（HdrA）的分子进化与功能分化 |
Banerjee, M. |
PDF |
N/A |
Molecular Evolution and Functional Divergence of Heterodisulfide Reductase A (HdrA) |
| 酒精对体外原肠胚形成的人类胚胎细胞的转录组、甲基组和代谢组的影响 |
Wallen, E. |
PDF |
N/A |
Effects of alcohol on the transcriptome, methylome, and metabolome of in vitro gastrulating human embryonic cells |
| 酶促蛋白质融合，产物收率达100% |
Fuchs, A. C. D. |
PDF |
N/A |
Enzymatic Protein Fusions with 100% Product Yield |
| 膜蛋白取向排列诱导的囊泡形状变化 |
Feng, M. |
PDF |
N/A |
Shape transformation of vesicles induced by orientational arrangement of membrane proteins |
| 内在无序蛋白质在其构象集合中可以表现出不同的聚合物行为。 |
Chakraborty, S. |
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N/A |
Intrinsically disordered proteins can behave as different polymers across their conformational ensemble |
| 脊髓投射的5-羟色胺能神经元对活跃运动状态的增强作用 |
Dasen, J. |
PDF |
N/A |
Potentiation of active locomotor state by spinal-projecting serotonergic neurons |
| 在存在内源性无药物脂质纳米颗粒的情况下，mRNA脂质纳米颗粒的结构表征 |
Chen, X. |
PDF |
N/A |
Structural Characterization of mRNA Lipid Nanoparticles in the Presence of Intrinsic Drug-free Lipid Nanoparticles |
| 一个分层贝叶斯模型揭示了随着内感受训练的进行，传入心脏信号的精确度权重增加，同时焦虑感降低。 |
Suksasilp, C. |
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N/A |
A hierarchical Bayesian model reveals increased precision weighting for afferent cardiac signals, and reduced anxiety, as a function of interoceptive training |
| 动作视频游戏玩家的背侧视觉流中的连接性增强 |
Cahill, K. |
PDF |
N/A |
Connectivity in the Dorsal Visual Stream is Enhanced in Action Video Game Players |
| Lrrk2和Snca缺陷变异不会改变新生小鼠因神经亲嗜性呼肠孤病毒T3D引起的原发性脑炎的病程。 |
Lunn, M. O. |
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N/A |
Variants in Lrrk2 and Snca deficiency do not alter the course of primary encephalitis due to neurotropic reovirus T3D in newborn mice |
| 桥联脂质转移蛋白3A（BLTP3A）与晚期内吞途径的膜相关，并作为CASM的效应器。 |
Hanna, M. G. |
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N/A |
Bridge-like lipid transfer protein 3A (BLTP3A) is associated with membranes of the late endocytic pathway and is an effector of CASM |
| 我们能从遗留物中发现什么：半水生昆虫蜕皮的DNA代谢条形码研究 |
Dworatzek, S. |
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N/A |
What we can find in what's left behind: DNA metabarcoding of semi-aquatic insect exuviae |
| tRNA池的进化塑造了Saccharomycotina亚门中密码子使用选择的变化 |
Cope, A. L. |
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N/A |
Evolution of tRNA pool shapes variation in selection on codon usage across the Saccharomycotina subphylu |
| 通过X染色体筛选和基因编辑获得的Ogden综合征（NAA10）和NAA15患者来源的诱导多能干细胞系及其同源配对库。 |
Wesely, J. |
PDF |
N/A |
A repository of Ogden syndrome (NAA10) and NAA15 patient derived iPSC lines and isogenic pairs by X-chromosome screening and genome-editing. |
| 选择促进线粒体基因组的年龄依赖性退化 |
Korotkevich, E. |
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Selection promotes age-dependent degeneration of the mitochondrial genome |
| 量化影响拟南芥基因RNA二级结构的SNP的进化 |
Martin, G. T. |
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Quantifying evolution of SNPs that affect RNA secondary structure in Arabidopsis thaliana genes |
| 一种经过计算设计的多样且选择性强的过氧化酶面板，用于萜类化合物的氧功能化 |
Munch, J. |
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N/A |
A computationally designed panel of diverse and selective peroxygenases for terpene oxyfunctionalization |
| 少即是多：慢密码子窗口增强eGFP mRNA对RNA干扰的抵抗力 |
Mueller, J. A. |
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Less is more: Slow-codon windows enhance eGFP mRNA resilience against RNA interference |
| 时间分辨的单个葡萄果实转录组：膜运输作为双S型生长的开关 |
Savoi, S. |
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Time-resolved transcriptomic of single V. vinifera fruits: membrane transports as switches of the double sigmoidal growth |
| MirGeneDB 3.0：改进的分类学采样，统一命名新发现的保守微RNA家族，以及更新的协方差模型。 |
Clarke, A. W. |
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N/A |
MirGeneDB 3.0: Improved taxonomic sampling, uniform nomenclature of novel conserved microRNA families, and updated covariance models. |
| irCLIP-RNP和Re-CLIP揭示了RNA上动态蛋白质关联的模式 |
DUCOLI, L. |
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irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA |
| 人类线粒体ClpP蛋白酶的变构激活机制 |
Goncalves, M. M. |
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Mechanism of allosteric activation in human mitochondrial ClpP protease |
| 一种用于胞内检测丙二酰辅酶A的基因编码荧光生物传感器 |
Ranzau, B. L. |
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A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA |
| 酶活性通过调节拥挤环境中的粘度来调控底物扩散 |
Bevilacqua, A. |
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Enzyme Activity Regulates Substrate Diffusion by Modulating Viscosity in Crowded Milieu |
| 溶血磷脂酰基团大小、酰基链长度及饱和度对液泡酸化、Ca²⁺转运及融合具有不同的影响。 |
Zhang, C. |
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Lysophospholipid headgroup size, and acyl chain length and saturation differentially affect vacuole acidification, Ca2+ transport, and fusion |
| Tris通过线性混合抑制机制抑制GH1 β-葡萄糖苷酶。 |
Chagas, R. S. |
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Tris inhibits a GH1 β-glucosidase by a linear mixed inhibition mechanism |
| 利用工程化受体实现合成mRNA的胞外配体响应性翻译调控 |
Nakanishi, H. |
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Extracellular ligand-responsive translational regulation of synthetic mRNAs using engineered receptors |
| novoStoic2.0：一个综合框架，用于路径合成、热力学评估和酶选择 |
Upadhyay, V. |
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novoStoic2.0: An integrated framework for pathway synthesis, thermodynamic evaluation, and enzyme selection |
| PEG调整使利用丝状支原体受体进行基因组移植成为可能 |
Karas, B. J. |
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PEG Adjustment Enables Genome Transplantation Using Mycoplasma Mycoides Recipient |
| AAV血清型转导嗅觉感觉神经元的比较分析 |
Belfort, B. D. |
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Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons |
| 一种双调蛋白报告基因小鼠能够实现修复性肺部调节性T细胞的转录和克隆扩增分析。 |
Loffredo, L. F. |
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An amphiregulin reporter mouse enables transcriptional and clonal expansion analysis of reparative lung Treg cells |
| 米诺环素增强了未极化巨噬细胞对鲍曼不动杆菌的抗菌活性，同时减少了炎症反应。 |
Guerra, A. D. |
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Minocycline enhances antimicrobial activity of unpolarized macrophages against Acinetobacter baumannii while reducing the inflammatory response |
| 克罗恩病最早的病变——口腔溃疡的转录组学特征表明，细菌侵袭性挑战而非整体菌群失调是引发因素。 |
Whiley, P. J. |
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Transcriptomic signatures of host immune responses in aphthous ulcers, the earliest lesions of Crohn's disease, suggest that a bacterial invasive challenge, rather than global dysbiosis, is the initiating factor. |
| 基因组导向研究揭示了一组磷脂酶，并突显了沙门氏菌T6SS效应蛋白的多样性。 |
Nicastro, G. G. |
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Genome-directed study uncovers a family of phospholipases and highlights the diversity of Salmonella T6SS effectors. |
| Tailocin介导的软腐病欧氏杆菌属细菌间的相互作用 |
Borowicz, M. |
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Tailocin-mediated interactions in Soft Rot Pectobacteriaceae |
| 弓形虫速殖子和缓殖子中的运动依赖性过程：相同却又不同 |
Kent, R. S. |
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Motility-dependent processes in Toxoplasma gondii tachyzoites and bradyzoites: same same but different |
| 通过深度测序结合平衡核苷酸合成内参法，对低生物量样本抗生素处理后16S基因拷贝进行精确定量 |
Chang, C.-C. |
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Accurate quantitation of 16S gene copies in low biomass samples post-antibiotic treatment through deep sequencing with a balanced nucleotide synthetic spike-in approach |
| Ing4缺失增强了多能祖细胞中的造血再生 |
Anderson, G. A. |
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Loss of Ing4 enhances hematopoietic regeneration in multipotent progenitor cells |
| 斑马鱼Pol-Theta和人Pol-Theta，具有同源功能的直系同源物 |
Thomas, C. |
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Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function |
| 由CRISPR-Cas9 DNA双链断裂引发的兆碱基级杂合性缺失 |
Regan, S. B. |
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Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks |
| 强效且选择性的SETDB1共价负变构调节剂可降低细胞中的甲基转移酶活性 |
Uguen, M. |
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Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells |
| AAV9介导的针对天然反义转录本的靶向治疗作为一种新型治疗手段用于Dravet综合征 |
Antinao Diaz, J. F. |
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AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome |
| 外膜变化使细菌能够逃避捕食者的进化 |
Mridha, S. |
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Outer membrane changes enable evolutionary escape from bacterial predation |
| 鉴定药物/代谢物转运蛋白1作为NF54xCam3.II恶性疟原虫遗传杂交中奎宁抗性的标志物。 |
Kanai, M. |
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Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54xCam3.II P. falciparum genetic cross. |
| 早期内体逃逸可提高所递送酶类货物的催化活性 |
Vazquez Maldonado, A. L. |
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Earlier endosomal escape improves the catalytic activity of delivered enzyme cargo |
| 通过在水相中使用角质酶或脂肪酶，实现含有酯键的氧化聚乙烯的高效降解 |
Kong, D. |
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Efficient degradation of oxidized polyethylene containing ester bonds by cutinase or lipase in aqueous phase |
| DNA聚合酶Zeta是一种强健的逆转录酶。 |
Mayle, R. |
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DNA polymerase Zeta is a robust reverse transcriptase |
| 建模锥虫运动 |
Overberg, F. A. |
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Modelling trypanosome motility |
| 秀丽隐杆线虫体细胞中核Argonaute蛋白HRDE-1和NRDE-3的独特调控机制。 |
Mendoza, H. |
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Distinct regulatory mechanisms by the nuclear Argonautes HRDE-1 and NRDE-3 in the soma of Caenorhabditis elegans. |
| 2型糖尿病和肥胖症中增加的骨炎症与Wnt信号下调和骨强度降低相关 |
Leanza, G. |
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Increased bone inflammation in type 2 diabetes and obesity correlates with Wnt signaling downregulation and reduced bone strength |
| 深度学习有助于植物抗病基因的精准鉴定 |
Liu, Z. |
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Deep learning facilitates precise identification of disease-resistance genes in plants |
| 在自然阅读过程中，对正字法和语义旁中央凹信息的快速层次处理 |
Wang, L. |
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Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading |
| AIM2对HNSCC发展的影响 |
Reinartz, D. M. |
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Impact of AIM2 on HNSCC Development |
| PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection |
Williams, D. E. |
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PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection |
| 军团菌自诱导物LAI-1的跨界信号传递涉及抗微生物鸟苷酸结合蛋白GBP。 |
Solger, F. |
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Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP |
| 鉴定和表征链球菌性猪病完全毒力所需的ugpE基因 |
Yang, Q. |
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Identification and characterization of ugpE required for the full virulence of Streptococcus suis |
| 在易患坏死性小肠结肠炎期间，对产后小肠转录组进行编目 |
Oliveria, L. F. S. |
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N/A |
Cataloguing the postnatal small intestinal transcriptome during the period of susceptibility to necrotizing enterocolitis |
| 嗜热菌G. icigianus细胞对太赫兹辐射的转录组响应 |
Bryanskaya, A. |
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The transcriptomic response of cells of the thermophilic bacterium G. icigianus to THz irradiation |
| 社交孤立压力对基于空间学习任务中涉及热威胁的安全学习和防御行为结构的影响 |
Villalon, S. A. |
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Impact of social isolation stress on safety learning and the structure of defensive behavior during a spatial-based learning task involving thermal threat |