| 利用双滴定微点测定法对血清抗体反应进行深度物化表征 |
Kovacs, A. |
PDF |
N/A |
Deep physico-chemical characterization of the serum antibody response using a dual-titration microspot assay |
| TMPRSS2对Omicron谱系Spike糖蛋白的激活受到ACE2的Collectrin样域的调控 |
Aggarwal, A. |
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N/A |
TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2 |
| 端粒通过非端粒TRF2控制人类端粒酶（hTERT）的表达。 |
Sengupta, A. |
PDF |
N/A |
Telomeres control human telomerase (hTERT) expression through non-telomeric TRF2 |
| 测序、Ludwigia叶绿体基因组的从头组装以及在Onagraceae科内的比较分析 |
Barloy-Hubler, F. |
PDF |
N/A |
Sequencing, de novo assembly of Ludwigia plastomes, and comparative analysis within the Onagraceae family |
| INSTINCT：通过随机域转换实现空间染色质可及性测序数据的多样本整合 |
Liu, Y. |
PDF |
N/A |
INSTINCT: Multi-sample integration of spatial chromatin accessibility sequencing data via stochastic domain translation |
| MTALTCO1：一种由线粒体DNA编码的259个氨基酸长的替代蛋白，挑战了传统线粒体基因组学的理解。 |
Robitaille, F. |
PDF |
N/A |
MTALTCO1: a 259 amino-acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics |
| 基于视频的生物力学分析捕捉到了不同神经肌肉疾病的疾病特异性运动特征。 |
Ruth, P. |
PDF |
N/A |
Video-based biomechanical analysis captures disease-specific movement signatures of different neuromuscular diseases |
| 在稻珊瑚（Montipora capitata）中，存在一种进化上保守的Hox-Gbx分节代码 |
He, S. |
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N/A |
An evolutionarily conserved Hox-Gbx segmentation code in the rice coral Montipora capitata |
| 慢性使用氟西汀会下调前额叶皮质中小清蛋白中间神经元的线粒体活性。 |
Jetsonen, E. |
PDF |
N/A |
Chronic treatment with fluoxetine downregulates mitochondrial activity in parvalbumin interneurons of prefrontal cortex |
| 从结构MRI图像生成合成TSPO PET图谱 |
Ferrante, M. |
PDF |
N/A |
Generation of synthetic TSPO PET maps from structural MRI images |
| 黑质外路易体病的模型中能量代谢改变和昼夜节律紊乱的分子特征。 |
Lin, L. |
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N/A |
Molecular signatures of altered energy metabolism and circadian rhythm perturbations in a model of extra-nigral Synucleinopathy. |
| 成骨细胞衍生的红细胞生成素调节应激性红细胞生成过程中的肝脏铁调素 |
Myneni, V. D. |
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N/A |
Osteocyte-derived erythroferrone regulates liver hepcidin during stress erythropoiesis |
| 芽殖酵母亚门中朊毒素样杀伤毒素的古老起源与高度多样性 |
Heneghan, P. G. |
PDF |
N/A |
Ancient origin and high diversity of zymocin-like killer toxins in the budding yeast subphylum |
| 心肌内皮素调节心肌细胞增殖与心脏再生 |
Sorensen, D. W. |
PDF |
N/A |
Myocardial Endoglin Regulates Cardiomyocyte Proliferation and Cardiac Regeneration |
| 在突变热点驱动的克隆性造血中未发现免疫监视的证据 |
Walkowiak, B. |
PDF |
N/A |
No evidence of immunosurveillance in mutation-hotspot driven clonal haematopoiesis |
| UPR诱导的细胞内C5aR1通过调节肿瘤细胞命运，促进对低氧肿瘤微环境的适应。 |
Suwa, T. |
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N/A |
UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment by regulating tumour cell fate |
| 人类肺癌恶病质的新型临床前模型 |
Snoke, D. B. |
PDF |
N/A |
Novel preclinical model of human lung cancer cachexia |
| 长非编码RNA UCA1通过含SMARCA2的SWI/SNF复合物影响人类结直肠癌中的染色质重塑。 |
Neve, B. |
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N/A |
Long non-coding RNA UCA1 affects chromatin remodeling via SMARCA2-containing SWI/SNF complex in human colorectal cancer. |
| 打破循环：如何通过靶向CD44v6/MET信号通路破坏结直肠癌细胞的可塑性 |
Sonnentag, S. J. |
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N/A |
Breaking the cycle: How targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity |
| 斑马鱼胶质-血管相互作用在脑发育过程中逐渐扩展 |
Gall, L. G. |
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N/A |
Zebrafish glial-vascular interactions progressively expand over the course of brain development |
| 父母照顾会改变早期体型和生长在塑造未来生理机能中的作用 |
Laubach, Z. M. |
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N/A |
Parental care modifies the role of early-life size and growth in shaping future physiology |
| 细菌运动模式能够平滑地适应空间限制和无序环境。 |
Zhang, H. |
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N/A |
Bacterial motility patterns adapt smoothly in response to spatial confinement and disorder |
| 鉴定SLC45A4为编码神经元多胺转运体的疼痛基因。 |
Middleton, S. J. |
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N/A |
Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter. |
| 基于将听觉伪词声音映射到多个意义域的声学参数组合：一种机器学习方法 |
Kumar, G. V. |
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N/A |
Acoustic parameter combinations underlying mapping of auditory pseudoword sounds to multiple domains of meaning: a machine learning approach |
| 当前人类神经科学研究中的报告实践 |
Gard, A. M. S. |
PDF |
N/A |
Current Reporting Practices in Human Neuroscience Research |
| 探索儿童非感染性葡萄膜炎中的微小RNA特征：患者样本的荟萃分析与分子谱分析 |
Wawrzyniak, O. |
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N/A |
Exploring MicroRNA Signatures in Pediatric Non-infectious Uveitis: Meta-Analysis and Molecular Profiling of Patient Samples |
| 小鼠胚胎植入前单细胞蛋白质组学揭示早期卵裂球中某些蛋白质的显著不对称性 |
Yuan, Y. |
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N/A |
Single-cell proteomics of pre-implantation mouse embryos uncovers distinct asymmetry of certain proteins among early blastomeres |
| 代谢重编程调控斑马鱼尾鳍再生过程中的组蛋白乳酸化 |
Borbinha, J. |
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N/A |
Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration |
| GoldPolish-目标：针对长读长基因组组装的靶向抛光 |
Zhang, E. |
PDF |
N/A |
GoldPolish-Target: Targeted long-read genome assembly polishing |
| 全血转录组分析揭示了运动神经元疾病（MND）的RNA生物标志物特征 |
Koks, S. |
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N/A |
Whole blood transcriptome profile identifies motor neurone disease (MND) RNA biomarker signatures |
| 鉴定出利什曼原虫中一种位于基体的新型ε-微管蛋白 |
Seth, A. |
PDF |
N/A |
Identification of a novel basal body-localized epsilon-tubulin in Leishmania |
| AFG3L2介导的蛋白水解作用在低氧条件下限制了线粒体生物合成和基因表达。 |
Chandragiri, S. |
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N/A |
AFG3L2-mediated proteolysis restricts mitochondrial biogenesis and gene expression in hypoxia |
| 一个MEF2C转录因子网络调控糖尿病肾病中肾小球内皮细胞的增殖 |
Melo Ferreira, R. |
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N/A |
A MEF2C transcripton factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease |
| 听觉毛细胞的静纤毛膜力学特性的动态调节通过机械转导复合体的混乱实现 |
Sam George, S. |
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N/A |
Dynamic modulation of auditory hair cell stereocilia membrane mechanics by the scrambling mechanotransduction complex |
| ALG-1，一种微RNA的Argonaute蛋白，促进了秀丽隐杆线虫的阴门诱导过程。 |
Zhen, S. |
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N/A |
ALG-1, a microRNA argonaute, promotes vulva induction in C. elegans |
| 从精子在卵母细胞中的运动轨迹推断，透明带和卵周间隙在促进配子融合和多精受精快速阻断中起关键作用。 |
Dubois, Y. |
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N/A |
Key roles of the zona pellucida and perivitelline space in promoting gamete fusion and fast block to polyspermy inferred from the choreography of spermatozoa in mice oocytes |
| p24家族成员TMED9通过快速内质网应激诱导的出口途径，将错误折叠的GPI锚定蛋白从内质网清除到高尔基体。 |
Ronzier, E. |
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N/A |
The p24-family member, TMED9, clears misfolded GPI-anchored proteins from theER to the Golgi via the Rapid ER Stress-Induced Export pathway |
| 人神经细胞图谱在发育中人脑组织中的寨卡感染：病毒发病机制、先天免疫和谱系重编程 |
Stokes, C. |
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N/A |
The Human Neural Cell Atlas of Zika Infection in developing human brain tissue: viralpathogenesis, innate immunity, and lineage reprogramming |
| 硫化叶菌属中基于社区的DNA修复机制的新组分 |
Recalde, A. |
PDF |
N/A |
New components of the community based DNA-repair mechanism in Sulfolobales |
| 分化方案依赖性变异性在人诱导多能干细胞衍生的内皮祖细胞功能中的表现 |
Stern, B. |
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N/A |
Differentiation Protocol-Dependent Variability in hiPSC-Derived Endothelial Progenitor Functionality |
| 久坐生活方式导致大鼠骨骼肌氧化应激和萎缩 |
Gungor, I. |
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N/A |
Sedentary lifestyle induces oxidative stress and atrophy in rat skeletal muscle |
| 大麻表达图谱：一个综合资源，用于大麻（Cannabis sativa L.）基因表达的整合分析 |
Barbosa-Xavier, K. |
PDF |
N/A |
Cannabis Expression Atlas: a comprehensive resource for integrative analysis of Cannabis sativa L. gene expression |
| 神经任务状态的主动重构 |
Ritz, H. |
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N/A |
Active reconfiguration of neural task states |
| 蜜蜂血脑屏障的超微结构组织及其与年龄的比较 |
Quigley, T. |
PDF |
N/A |
Ultrastructural Organization of the Honeybee Blood-Brain Barrier and Comparison with Age |
| 使用统一流程对多中心大鼠感觉诱发功能磁共振成像数据集进行激活图谱绘制。 |
Galteau, M. E. |
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N/A |
Activation mapping in multi-center rat sensory-evoked functional MRI datasets using a unified pipeline. |
| 裸盖菇素可防止小鼠初级听觉皮层对熟悉刺激的习惯化，并在反复刺激后保持对声音的敏感性。 |
Lane, C. P. |
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N/A |
Psilocybin prevents habituation to familiar stimuli and preserves sensitivity to sound following repeated stimulation in mouse primary auditory cortex. |
| 针对神经纤毛蛋白-1以增强黑色素瘤免疫治疗：减少肿瘤进展及外周Treg介导的免疫抑制 |
Khamaru, S. |
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N/A |
Targeting Neuropilin-1 to Enhance Immunotherapy in Melanoma: Reducing Tumour Progression and Peripheral Treg-Mediated Immunosuppression |
| 颗粒溶素抗菌活性促进结核分枝杆菌进入休眠状态 |
Schmidiger, S. |
PDF |
N/A |
Granulysin antimicrobial activity promotes dormancy in Mycobacterium tuberculosis |
| 路杀是迁徙性帝王蝶数量下降的关键因素 |
Momeni-Dehaghi, I. |
PDF |
N/A |
Roadkill is a crucial factor in the population decline of migratory monarch butterflies |
| 河流网络中的多种压力源：对淡水大型无脊椎动物的局部及下游影响 |
Burgazzi, G. |
PDF |
N/A |
Multiple stressors in river networks: local and downstream effects on freshwater macroinvertebrates |
| 蝴蝶花蜜知识的三重量子飞跃：全面研究革新保护策略 |
Dunlap, S. C. |
PDF |
N/A |
Three Fold Quantum Leap in Butterfly Nectar Knowledge: A Comprehensive Study Revolutionizing Conservation Strategies |
| 通过原生短暂低氧成像技术观察组织损伤、水肿区域及前哨淋巴结的淋巴动态。 |
Mendoza, M. I. O. |
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N/A |
Lymphatic dynamics visualized by native transient hypoxia imaging in areas of tissue damage, edema and in sentinel lymph nodes. |
| 曲霉菌细胞壁完整性激酶MpkA影响改变菌丝材料力学性能的细胞表型 |
Gray, K. |
PDF |
N/A |
Aspergillus nidulans cell wall integrity kinase, MpkA, impacts cellular phenotypes that alter mycelial-material mechanical properties |
| 预测透析器选择和透析液流速对胆红素清除的影响 |
Novokhodko, A. |
PDF |
N/A |
Predicting the Impact of Dialyzer Choice and Binder Dialysate Flow Rate on Bilirubin Removal |
| 通过加权TREE-QMC方法，提高了对基因树不完整性、估计误差和系统性同源错误（homology errors）的鲁棒性。 |
Han, Y. |
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N/A |
Improved robustness to gene tree incompleteness, estimation errors, and systematic homology errors with weighted TREE-QMC |
| 基于线粒体功能和细胞死亡模式的肝细胞癌患者MPCD指数 |
Wang, L.-X. |
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N/A |
MPCD Index for Hepatocellular Carcinoma Patients Based on Mitochondrial Function and Cell Death Patterns |
| 通过透析环境中环糊精实现膜甾醇水平的可逆调节 |
Alsayyah, C. |
PDF |
N/A |
Reversible tuning of membrane sterol levels by cyclodextrin in a dialysis setting |
| LC8通过异质性桥接53BP1寡聚体来增强53BP1焦点 |
Howe, J. |
PDF |
N/A |
LC8 enhances 53BP1 foci through heterogeneous bridging of 53BP1 oligomers |
| 用于单分子显微镜的可重复使用微流控室 |
Alfehaid, J. |
PDF |
N/A |
Reusable Microfluidic Chambers for Single-Molecule Microscopy |
| 细胞在受限迁移过程中牵引力的测量 |
Hockenberry, M. A. |
PDF |
N/A |
Measurement of cellular traction forces during confined migration |
| 衰老和瓦螨寄生对蜜蜂血脑屏障的细胞旁通透性和跨细胞通透性的影响 |
Quigley, T. P. |
PDF |
N/A |
Effect of aging and Varroa parasitism on the paracellular and transcellular permeability of the honeybee blood-brain barrier |
| 同步化的染色质组织作为基于麻醉的植物意识中的强效生物标志物 |
Chandra, S. |
PDF |
N/A |
Synchronized Chromatin Organization Serves as Potent Biomarker in Anaesthesia-based Plant Consciousness |
| 通过结合免疫荧光和RNA原位杂交技术，在细胞核内同时观察到Pol II和马铃薯纺锤块茎类病毒RNA。 |
Ma, J. |
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N/A |
Simultaneous observation of Pol II and potato spindle tuber viroid RNA in the nucleus by combining immunofluorescence and RNA in situ hybridization |
| 番茄中辣椒红素/辣椒玉红素合酶的表达改变了果实类胡萝卜素库，并增强了维生素A原的风味挥发性物质 |
Fu, J. |
PDF |
N/A |
Expression of Capsanthin/Capsorubin Synthase in Tomato Alters Fruit Carotenoid Pools, and Flavor Volatiles Enhancing Provitamin A |
| 虚拟植物实验室：一个基于Julia的现代化植物建模框架 |
Morales, A. |
PDF |
N/A |
The Virtual Plant Laboratory: a modern plant modeling framework in Julia |
| 在帕金森病小鼠模型中，恢复多巴胺能神经元中的Fbxo7表达可恢复酪氨酸羟化酶 |
Laman, H. |
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N/A |
Restoration of Fbxo7 expression in dopaminergic neurons restores tyrosine hydroxylase in a mouse model of Parkinson's disease |
| LPS诱导的小鼠类谵妄行为和微胶质激活与双谱脑电图（BSEEG）相关 |
Nishiguchi, T. |
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N/A |
LPS-induced delirium-like behavior and microglial activation in mice correlate with bispectral electroencephalography (BSEEG) |
| 当注意力受到伤害：rTMS对时间知觉神经相关性的影响 |
Conto, F. |
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N/A |
When Attention Hurts: The Effect Of rTMS On Neural Correlates Of Time Perception |
| 蓝斑核磁共振完整性与结构体积的逆向关联及其对个体注意力不集中的影响 |
Neal, J. |
PDF |
N/A |
Inversed association of locus coeruleus MRI integrity with structural volume and its impact on individual's inattentiveness |
| 时间压力下目标导向控制与习惯性控制之间的情境依赖性交互作用 |
Froelich, S. |
PDF |
N/A |
Context-Dependent Interaction Between Goal-Directed and Habitual Control Under Time Pressure |
| 非侵入性大脑刺激前额极皮质可促进在类似觅食的序列选择任务中付出认知努力的意愿 |
Bogdanov, M. |
PDF |
N/A |
Non-invasive brain stimulation over the Frontopolar Cortex promotes willingness to exert cognitive effort in a foraging-like sequential choice task |
| 全皮层θ振荡的时空模式与自由移动行为相耦合 |
Sattler, N. J. |
PDF |
N/A |
Cortex-wide spatiotemporal motifs of theta oscillations are coupled to freely moving behavior |
| 年龄和地区特异性代谢物浓度校正的水放松图谱 |
Simegn, G. L. |
PDF |
N/A |
A Water Relaxation Atlas for Age and Region specific Metabolite Concentration Correction |
| 通过在神经元中删除质子激活的氯离子通道，导致内体过度酸化，从而损害AMPA受体的内吞作用和长时程抑制（LTD）。 |
Chen, K. |
PDF |
N/A |
Endosomal hyper-acidification via proton-activated chloride channel deletion in neurons impairs AMPA receptor endocytosis and LTD |
| 致幻剂假说：通过依赖回放的可塑性机制来模拟经典致幻剂的幻觉效应 |
Bredenberg, C. |
PDF |
N/A |
The oneirogen hypothesis: modeling the hallucinatory effects of classical psychedelics in terms of replay-dependent plasticity mechanisms |
| ACE1不影响5XFAD小鼠大脑中Aβ降解或淀粉样斑块的积累 |
Jeon, S. |
PDF |
N/A |
ACE1 Does Not Influence Cerebral Aβ Degradation or Amyloid Plaque Accumulation in 5XFAD Mice |
| 内质网应激调节因子IRE1α的激活会损害肺部宿主防御功能。 |
Sharma, A. |
PDF |
N/A |
Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses |
| 环境机械异质性对T细胞功能的影响 |
Pandit, J. J. |
PDF |
N/A |
Effect of the Environmental Mechanical Heterogeneity on T Cell Function |
| 损伤诱导的IL-18刺激胸腺NK细胞，限制内源性组织再生 |
Granadier, D. |
PDF |
N/A |
Damage-induced IL-18 stimulates thymic NK Cells limiting endogenous tissue regeneration |
| 衰老的僵硬交响曲：衰老的骨细胞如何失去它们的弹性节奏 |
Tilton, M. |
PDF |
N/A |
Stiffening Symphony of Aging: How Senescent Osteocytes Lose Their Elastic Rhythm |
| PA2G4、MCRS1和SOBP对SIX1+EYA转录活性的直接和间接调控 |
Jourdeuil, K. |
PDF |
N/A |
Direct and Indirect Regulation of SIX1+EYA Transcriptional Activity by PA2G4, MCRS1, and SOBP |
| 在农业土壤中，线虫拮抗物的多样性及其受根结线虫密度和覆盖作物影响的可调控性 |
Cazzaniga, S. G. |
PDF |
N/A |
On the diversity of nematode antagonists in an agricultural soil, and their steerability by root-knot nematode density and cover crops |
| 一种用于两栖动物、龟类和鱼类eDNA元条形码的新型简并引物组 |
Rodgers, T. W. |
PDF |
N/A |
A novel degenerate primer set for eDNA metabarcoding of amphibians, turtles and fish |
| 缺氧威胁珊瑚和海葵的早期生命阶段 |
Glass, B. H. |
PDF |
N/A |
Hypoxia threatens coral and sea anemone early life stages |
| 在中国，多样化措施减轻了农药对蜜蜂的影响，但未能减轻微塑料的影响，同时并未影响油菜籽产量。 |
Lin, W. |
PDF |
N/A |
Diversification mitigates pesticide but not microplastic effects on bees without compromising rapeseed yield in China |
| 在近期经历过多倍体化和基因渐渗的植物属中，基因树拓扑空间的地形 |
Landis, J. |
PDF |
N/A |
The topography of gene tree topology space in a plant genus with a legacy of recent polyploidy and introgression |
| CAYSS：用于酵母孢子分离自动流式细胞分析的软件包 |
Raffoux, X. |
PDF |
N/A |
CAYSS: package for automatic Cytometry Analysis of Yeast Spore Segregation |
| 光合共生塑造了巨蛤的基因组结构与基因进化 |
Li, R. |
PDF |
N/A |
Photosymbiosis Shaped Animal Genome Architecture and Gene Evolution as Revealed in Giant Clams |
| 追踪串联重复序列：一种可定制的识别和跨物种比较的管道 |
de Lima Adam, C. |
PDF |
N/A |
TRACKing Tandem Repeats: a customizable pipeline for identification and cross-species comparisons |
| 昼行性啮齿动物——白尾黄鼠（Ammospermophilus leucurus）中，昼夜节律的同步化缺失及对周期性厌恶刺激的夜间可塑性有限 |
Zhang, V. |
PDF |
N/A |
Lack of circadian entrainment and limited nocturnal plasticity in response to a cyclic aversive stimulus in a diurnal rodent, the antelope ground squirrel (Ammospermophilus leucurus) |
| 随着年龄增长，小鼠子宫的生物力学和组成变化 |
Domingo, M. J. E. |
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N/A |
Biomechanical and Compositional Changes in the Murine Uterus with Age |
| 电休克疗法和磁休克疗法诱发癫痫的最佳频率 |
Peterchev, A. V. |
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N/A |
Optimal Frequency for Seizure Induction with Electroconvulsive Therapy and Magnetic Seizure Therapy |
| 使用混合融合Transformer从CT中精炼心肌分割 |
Qin, S. |
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N/A |
Refined Myocardium Segmentation from CT Using a Hybrid-Fusion Transformer |
| 基于模型的强化学习用于超声驱动的自主微型机器人 |
Medany, M. |
PDF |
N/A |
Model-Based Reinforcement Learning for Ultrasound-Driven Autonomous Microrobots |
| 不同的基因调控网络调控造血干细胞和白血病干细胞 |
Zhang, B. |
PDF |
N/A |
Distinct gene regulatory networks govern hematopoietic and leukemia stem cells |
| FragLlama：分子设计的下一个片段预测 |
Che, X. |
PDF |
N/A |
FragLlama: Next-fragment prediction for molecular design |
| 五物种进化空间循环博弈中存在缺失和非缺失优势网络的长期物种共存 |
Cliff, D. |
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N/A |
On Long-Term Species Coexistence in Five-Species Evolutionary Spatial Cyclic Games with Ablated and Non-Ablated Dominance Networks |
| 《你好，你好》：高效预测变构位点的数据驱动方法 |
Dong, T. |
PDF |
N/A |
Allo-Allo: Data-efficient prediction of allosteric sites |
| LightMed：一种轻量级且基于FFT的鲁棒模型，用于对抗性弹性的医学图像分割 |
Pham, V. T. |
PDF |
N/A |
LightMed: A Light-weight and Robust FFT-Based Model for Adversarially Resilient Medical Image Segmentation |
| 利用荧光相关光谱技术对体外裂解液中合成的蛋白质进行实时亲和力测量的方法 |
Liu, C. |
PDF |
N/A |
Real-time affinity measurements of proteins synthesized in cell-free lysate using fluorescence correlation spectroscopy |
| 单克隆抗体与两亲性聚合物在气-水界面上的竞争吸附 |
Hingst, E. J. |
PDF |
N/A |
Competitive Adsorption of a Monoclonal Antibody and Amphiphilic Polymers to the Air-Water Interface |
| RapA 打开 RNA 聚合酶夹，以破坏终止后复合物并防止形成细胞毒性 R 环。 |
Brewer, J. J. |
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N/A |
RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation |
| 细胞内细胞器在运输途径中的主动形态动力学 |
Rautu, S. A. |
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N/A |
Active morphodynamics of intracellular organelles in the trafficking pathway |
| 冷冻电镜展示了驱动蛋白激活途径的多个步骤 |
Kendrick, A. |
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N/A |
Cryo-EM visualizes multiple steps of dynein activation pathway |
| 纳米团簇介导的巨噬细胞炎症反应中FcγR与TLR4之间的信号交叉对话 |
Lee, S. |
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N/A |
Nanocluster-Mediated Signaling Crosstalk between FcγR and TLR4 in Macrophage Inflammatory Responses |
| 潜在的TGF-β具有一种域交换的结构。 |
Jin, M. |
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N/A |
Latent-TGF-β has a domain swapped architecture |
| 不同的神经内分泌亚型预测治疗诱导的神经内分泌前列腺癌预后，并为个性化治疗提供线索 |
Hong, Y.-C. |
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N/A |
Distinct neuroendocrine subtypes predict treatment-induced neuroendocrine prostate cancer prognosis and provide clues for personalized treatment |
| 茎水含量对于在地中海气候下热浪期间支持果树功能至关重要。 |
Rez, L. |
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N/A |
Stem water content is crucial to support fruit tree functioning during heatwaves in a Mediterranean climate |
| 野生葡萄品种对气候变化的适应动态有助于培育具有气候适应性的葡萄及其砧木。 |
Zhang, M. |
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N/A |
The dynamics of wild Vitis species in response to climate change facilitate the breeding of grapevine and its rootstocks with climate resilience |
| 整合耐寒性和抗去驯化能力表明葡萄藤对寒冷积累的保守反应。 |
Londo, J. P. |
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N/A |
Integrating cold hardiness and deacclimation resistance demonstrates a conserved response to chilling accumulation in grapevines. |
| 利用自然低氧应答因子设计的反馈机制增强了合成低氧生物传感器 |
Dreyer, K. S. |
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N/A |
Engineered Feedback Employing Natural Hypoxia-Responsive Factors Enhances Synthetic Hypoxia Biosensors |
| 氧化还原信号在脂肪组织分泌组中炎症细胞因子诱导的脂肪前体细胞分化中起介导作用 |
Wager, J. L. |
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N/A |
Redox Signaling Mediates Differentiation of Adipose Progenitors in Response to Inflammatory Cytokines in the Adipose Tissue Secretome |
| 艾森侧抑制任务中行为和电生理标记的重测信度和重复性 |
Bogdanov, M. |
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N/A |
Test-Retest Reliability and repeatability of Behavioral and Electrophysiological Markers in an Eriksen Flanker Task |
| 评估基于头皮的DLPFC定位方法用于TMS治疗：EEG帽F3、光束F3、CPC F3及调整后的光束F3 |
Jiang, Y. |
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N/A |
Evaluation of scalp-based targeting methods of DLPFC for TMS therapy: EEG cap F3, Beam F3, CPC F3, and adjusted Beam F3 |
| 系统性催产素和β3受体激动剂（CL 316243）治疗对雄性饮食诱导肥胖大鼠体重和脂肪含量的影响 |
Slattery, J. D. |
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N/A |
Effects of systemic oxytocin and beta-3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet-induced obese rats |
| 利用扩散磁共振成像技术在体内绘制人脑皮层微观结构图 |
Sadikov, A. |
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N/A |
Mapping the Microstructure of Human Cerebral Cortex In Vivo with Diffusion MRI |
| 状态和特质血清素变化相互作用，塑造了大脑的内在连接性和梯度结构：一项结合TPH2遗传学和色氨酸耗竭的研究 |
Wang, L. |
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N/A |
State and trait serotonin variations interact to shape the intrinsic connectivity and gradient architecture of the brain: a combined TPH2 genetics and tryptophan depletion study |
| 元控制状态的神经生理动力学：脑电图对冲突调节的洞察 |
Wang, X. |
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N/A |
Neurophysiological Dynamics of Metacontrol States: EEG Insights into Conflict Regulation |
| 雄性小鼠在寻求奖励过程中伏隔核神经元的时序动力学 |
Schall, T. A. |
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N/A |
Temporal Dynamics of Nucleus Accumbens Neurons in Male Mice During Reward Seeking |
| 左旋多巴在体外损害感觉神经元的溶酶体功能 |
Olaoye, O. J. |
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N/A |
Levodopa impairs lysosomal function in sensory neurons in vitro |
| 人类CaV2.1通道的可用性背后隐藏着丰富的构象多样性。 |
Wang, K. |
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N/A |
A rich conformational palette underlies human CaV2.1-channel availability |
| 靶向组织的初免/加强/维持治疗性单纯疱疹病毒疫苗保护HLA-A*0201转基因兔免受复发性眼部疱疹疾病的侵害 |
Chentoufi, A. |
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N/A |
Tissue-Targeted Prime/Pull/Keep Therapeutic Herpes Simplex Virus Vaccine Protect Against Recurrent Ocular Herpes Diseases in HLA-A*0201 Transgenic Rabbits |
| 探索UVB敏感性与系统性红斑狼疮活动性之间的关联：深入了解紫外线B驱动的红斑狼疮发病机制 |
He, J. |
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N/A |
Exploring the Correlation Between UVB Sensitivity and SLE Activity: Insights into UVB-Driven Pathogenesis in Lupus Erythematosus |
| 缺氧条件下的效应T细胞具有与非应答性黑色素瘤患者中发现的肿瘤应激T细胞相似的转录组改变。 |
Nagy, M. Z. |
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N/A |
Effector T Cells under Hypoxia have an Altered Transcriptome Similar to Tumor-Stressed T Cells Found in Non-Responsive Melanoma Patients |
| 体内T细胞共调节因子B7-H4的成像揭示了前列腺癌中的促肿瘤巨噬细胞状态 |
Kumar, M. |
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N/A |
In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer |
| 利用新型自噬体分离方法对饥饿和运动期间自噬货物谱的表征 |
Liu, Y. |
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N/A |
Characterization of Autophagy Cargo Profiles during Starvation and Exercise with a Novel Autophagosome Isolation Method |
| 结肠炎症的性别差异是由上皮特异性表达的雌激素受体α驱动的。 |
Pereda, G. A. |
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N/A |
Sex differences in colonic inflammation are driven by epithelial-specific expression of estrogen receptor alpha |
| 利用cardiodeleter系统优化快速且稳健地生成斑马鱼心肌细胞特异性crispr的方法 |
Keeley, S. |
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N/A |
Optimization of methods for rapid and robust generation of cardiomyocyte-specific crispants in zebrafish using the cardiodeleter system |
| 全球模式、驱动因素及羊膜动物代谢特征的影响 |
Yang, Q. |
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N/A |
Global patterns, drivers and impacts of metabolic traits across amniotes |
| 早期人属生物进入东南亚地区引发了主要人类疟疾病媒的进化。 |
Singh, U. S. |
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N/A |
Early hominin arrival in Southeast Asia triggered the evolution of major human malaria vectors |
| 高吞吐量靶向扩增子筛选工具，用于直接从样本中表征金黄色葡萄球菌宿主内多样性 |
Furstenau, T. N. |
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N/A |
High-throughput targeted amplicon screening tool for characterizing intrahost diversity in Staphylococcus aureus directly from sample |
| 微流体法制备的超薄、可操作胶原蛋白片材表现出趾跟拉伸行为 |
Zhang, Y. |
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N/A |
Microfluidic Formation of Ultrathin, Handleable Collagen Sheets Exhibiting Toe-heel Tensile Behavior |
| 依赖于浓度的CsrA对uxuB转录本的调控导致转录后BANDPASS滤波器的形成 |
Rojano-Nisimura, A. M. |
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N/A |
Concentration dependent CsrA regulation of the uxuB transcript leads to development of post-transcriptional BANDPASS Filter |
| 追踪骨细胞衰老：骨细胞细胞骨架力学和形态的时变变化 |
Liao, J. |
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N/A |
Tracing Cellular Senescence in Bone: Time-Dependent Changes in Osteocyte Cytoskeleton Mechanics and Morphology |
| 环氧合酶-2的破坏易导致保留射血分数的心力衰竭 |
Ricciotti, E. |
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N/A |
Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction |
| 以非蛋白质氨基酸为测试案例，采用一种新的化学分类学方法 |
Gibson, M. |
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N/A |
A new spin on chemotaxonomy using non-proteogenic amino acids as a test case |
| 成年创伤性脑损伤后，使用脂多糖进行免疫挑战会迅速改变神经炎症和肠道微生物群，但对慢性结果影响甚微。 |
Rewell, S. S. J. |
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N/A |
A post-injury immune challenge with lipopolysaccharide following adult traumatic brain injury alters neuroinflammation and the gut microbiome acutely, but has little effect on chronic outcomes |
| 初级视觉皮层中视觉空间的深度图 |
He, Y. |
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N/A |
A depth map of visual space in the primary visual cortex |
| 在循环网络中，序列神经活动的自发涌现与漂移 |
Shao, S. |
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N/A |
Spontaneous emergence and drifting of sequential neural activity in recurrent networks |
| 解读激活和共刺激抗体在纳米尺度聚集对T细胞激活的作用 |
Le Saux, G. |
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N/A |
Deciphering the role of the nanoscale clustering of activating and costimulatory antibodies on T cell activation |
| 利用CRISPR激活技术快速评估人类多能干细胞中的基因编辑产物 |
Wu, Y. |
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N/A |
Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells |
| 利用时间动力学的定量相位成像预测造血干细胞的多样性 |
Yogo, T. |
PDF |
N/A |
Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity |
| 多用途动态体积生物成像的多功能光场显微平台 |
Bai, Y. |
PDF |
N/A |
A Versatile Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bio-imaging |
| 冠蜥（Correlophus ciliatus）染色体水平基因组组装与注释：一种无法再生尾巴的蜥蜴 |
Gumangan, M. |
PDF |
N/A |
Chromosome-level genome assembly and annotation of the crested gecko, Correlophus ciliatus, a lizard incapable of tail regeneration |
| 改善土壤中病毒的可视化 |
Parvate, A. D. |
PDF |
N/A |
Improving the visualization of viruses in soil |
| 铜绿微囊藻暴露于大薸和水葫芦水提液的生理响应 |
Silva, L. d. O. |
PDF |
N/A |
Physiological response of Microcystis aeruginosa exposed to aqueous extracts of Pistia stratiotes and Pontederia crassipes |
| 一种前所未有的微小RNA-核开关相互作用控制着一种双功能泵的表达，这种泵对金黄色葡萄球菌感染至关重要。 |
Gonzalez-Espinoza, G. |
PDF |
N/A |
An unprecedented small RNA-riboswitch interaction controls expression of a bifunctional pump that is essential for Staphylococcus aureus infection |
| 嗜热绿弯菌外膜小泡可能是生物硫运输的重要途径。 |
Noundou, V. L. |
PDF |
N/A |
Chlorobaculum tepidum Outer Membrane Vesicles Are Likely a Significant Route for Biogenic Sulfur Transport. |
| 饮食中的L-3,4-二羟基苯丙氨酸（L-DOPA）增强了按蚊外骨骼的黑色素化，同时缩短了它们的寿命并减少了疟原虫的负担。 |
Camacho, E. |
PDF |
N/A |
Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in Anopheles mosquitos while reducing their lifespan and malaria parasite burden |
| 普拉梭菌调节C57BL/6小鼠肠道微生物群的碳水化合物代谢功能 |
Geng, P. |
PDF |
N/A |
Faecalibacterium prausnitzii regulates carbohydrate metabolic functions of the gut microbiome in C57BL/6 mice |
| 长读宏基因组学能够精确追踪细菌菌株及其在粪菌移植后的基因组变化。 |
Fan, Y. |
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N/A |
Long-read metagenomics empowers precise tracking of bacterial strains and their genomic changes after fecal microbiota transplantation |
| 新型抗碳青霉烯类肺炎克雷伯菌噬菌体的特性分析 |
Kim, B. |
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N/A |
Characterization of newly isolated bacteriophages targeting carbapenem-resistant Klebsiella pneumoniae |
| 在2019年至2021年间，法国诺曼底地区解剖的马科动物中，艰难梭菌的感染情况：产毒菌株的普遍携带及新兴的017型菌株的毒力 |
Petry, S. |
PDF |
N/A |
Clostridioides difficile in Equidae necropsied in Normandie, France from 2019 to 2021: common carriage of toxigenic strains and virulence of emerging ribotype 017 |
| Typhi Mykrobe：直接从序列读取中快速且准确地识别伤寒沙门氏菌的谱系及抗菌药物耐药性基因分型 |
Ingle, D. J. |
PDF |
N/A |
Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent Salmonella Typhi |
| 两个跨膜转录调节因子协同作用，激活了霍乱弧菌中由几丁质诱导的自然转化过程。 |
Hullinger, A. C. |
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N/A |
Two transmembrane transcriptional regulators coordinate to activate chitin-induced natural transformation in Vibrio cholerae |
| 二萜类植物抗毒素塑造了水稻根系微生物群及其与根寄生线虫的关联 |
Kudjordjie, E. N. |
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N/A |
Diterpenoid phytoalexins shape rice root microbiomes and their associations with root parasitic nematodes |
| 一项针对多种土壤类型和地理区域抗生素抗性的宏基因组研究 |
Pillay, S. |
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N/A |
A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations |
| 一种宿主导向的佐剂可复苏并增强抗生素对胞内细菌持留菌的敏感性。 |
Lu, K.-Y. |
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N/A |
A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics |
| NPC1L1介导的27-羟基胆固醇代谢在骨质疏松发生发展中的机制 |
Li, B. |
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N/A |
Mechanism of NPC1L1 mediated 27-hydroxycholesterol metabolisms in the occurrence and development of osteoporosis |
| 生物固体改良对土壤抗性组和微生物组的影响 - 温室研究 |
Ste.Marie, J. P. |
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N/A |
Impact of biosolids amendment on the soil resistome and microbiome - a greenhouse study |
| 一种用于心脏特异性基因沉默的腺嘌呤碱基编辑器的多功能AAV载体 |
Liu, Z. |
PDF |
N/A |
An all-in-one AAV vector for cardiac-specific gene silencing by an adenine base editor |
| 伏隔核电刺激后脑分子景观的变化 |
Cai, C. |
PDF |
N/A |
Change in brain molecular landscapes following electrical stimulation of the nucleus accumbens |
| 马洛：利用从头肽段鉴定技术对法医学中的未知样本进行分类表征 |
Jenson, S. C. |
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N/A |
MARLOWE: Taxonomic Characterization of Unknown Samples for Forensics Using De Novo Peptide Identification |
| 高通量多样化蛋白质-配体表面以发现化学诱导接近剂 |
Shaum, J. B. |
PDF |
N/A |
High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity |
| 体内碘代酪氨酸尿代谢物的鉴定与测定 |
Ji, C. X. |
PDF |
N/A |
Identification and determination of the urinary metabolite of iodotyrosine in vivo |
| 甲烷产生古菌Methanococcus maripaludis中的糖原磷酸化酶：一种不依赖吡哆醛5'-磷酸的磷酸化酶的独特调节特性 |
Gonzalez-Ordenes, F. |
PDF |
N/A |
Glycogen phosphorylase from the methanogenic archaeon Methanococcus maripaludis: Unique regulatory properties of a pyridoxal 5'-phosphate independent phosphorylase |
| 持续性和爆发性电微刺激对皮层兴奋性和抑制性神经元激活的时空特性 |
Hughes, C. |
PDF |
N/A |
Spatiotemporal properties of cortical excitatory and inhibitory neuron activation by sustained and bursting electrical microstimulation |
| 基于核酶的生物传感器用于植物基因表达成像 |
Liu, Y. |
PDF |
N/A |
Ribozyme-based biosensor for imaging gene expression in plants |
| 以线粒体为中心的包涵体肌炎代谢组图谱：中心碳代谢的性别特异性改变 |
Naddaf, E. |
PDF |
N/A |
Mitochondria-centered metabolomic map of inclusion body myositis: sex-specific alterations in central carbon metabolism |
| 将地理空间工具整合于绘制坦桑尼亚鲁索托西乌桑巴拉山森林火灾严重程度和烧毁区域图 |
Mkiwa, B. P. |
PDF |
N/A |
Integrating geospatial tools in mapping forest fire severity and burned areas in the Western Usambara Mountain Forests, Lushoto, Tanzania |
| FIGL1限制了拟南芥中减数分裂非交叉事件的形成 |
Charif, D. |
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N/A |
FIGL1 limits the formation of meiotic non crossover events in Arabidopsis thaliana |
| 一种导致常染色体显性肥厚型心肌病的ALPK3截短变异体通过马瓦卡姆汀部分得到挽救 |
Leinhos, L. |
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N/A |
An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten |
| 通过多巴胺交联稳定模拟胶原蛋白三螺旋及其组装结构 |
Cole, C. C. |
PDF |
N/A |
Covalent Stabilization of Collagen Mimetic Triple Helices and Assemblies by Dopa Crosslinking |
| 组织特异性和空间依赖性的代谢特征在骨骼成熟的雄性和雌性C57Bl/6J小鼠中因损伤而受到干扰 |
Welhaven, H. D. |
PDF |
N/A |
Tissue-specific and spatially dependent metabolic signatures perturbed by injury in skeletally mature male and female C57Bl/6J mice |
| 恶性疟原虫NCR1膜蛋白是一种新型抗疟疾靶点，负责将胆固醇输出以维持膜稳态。 |
Zhang, Z. |
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N/A |
The Plasmodium falciparum NCR1 membrane protein is a novel antimalarial target that exports cholesterol to maintain membrane homeostasis |
| 选择性波段红外脉冲回波光谱（Band-selective IR PRESS）用于脑肿瘤光谱分析，能够稳健地检测乳酸。 |
Kishimoto, S. |
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N/A |
Band-selective IR PRESS for brain tumor spectroscopy allows robust detection of lactate |
| R2DT：一个用于可视化RNA二级结构的全面平台 |
McCann, H. |
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N/A |
R2DT: a comprehensive platform for visualising RNA secondary structure |
| 早期呼吸道合胞病毒感染对特定细胞类型气道DNA甲基化的影响 |
McKennan, C. |
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Impact of early-life respiratory syncytial virus infection on cell type-specific airway DNA methylation |