跳转至

2024-10-12 每日论文

来源 独立页面
arXiv arXiv
bioRxiv bioRxiv
medRxiv medRxiv

arXiv

标题 作者 PDF链接 代码仓库 Title

bioRxiv

标题 作者 PDF链接 代码仓库 Title
催乳素和DNA损伤会引发抗乳腺癌细胞的免疫反应。 Karayazi Atici, O. PDF N/A Prolactin and DNA damage trigger an anti-breast cancer cellimmune response
启动子近端暂停的进化实现了一层新的转录调控 Chivu, A. G. PDF N/A Evolution of promoter-proximal pausing enabled a new layer of transcription control
北极猛禽的狐步迁徙及动态越冬范围 Pokrovsky, I. PDF N/A Foxtrot migration and dynamic over-wintering range of an arctic raptor
利用光遗传学控制RhoA的GEF揭示了从收缩到突起的信号开关 de Seze, J. PDF N/A Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion
小鼠眶额皮层中信息内在价值的表征 Bussell, J. J. PDF N/A Representations of the intrinsic value of information in mouse orbitofrontal cortex
蚊子发育过程中细菌代谢物的营养性别特异性导致成虫性别比例失衡 Romoli, O. PDF N/A Nutritional sex-specificity on bacterial metabolites during mosquito development leads to adult sex-ratio distortion
经过验证的触摸视频数据库 Smit, S. PDF N/A The validated touch-video database
重新思考休眠:抗生素持久者是具有代谢活性、非生长的细胞 Rahman, K. M. T. PDF N/A Rethinking Dormancy: Antibiotic Persisters are Metabolically Active, Non-Growing Cells
尼古丁通过Hippo-YAP/TAZ和Notch信号通路增强肠干细胞的干性和肿瘤发生能力。 Isotani, R. PDF N/A Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway
有效连接预测感知决策信心、不确定性和速度的分布式神经编码 Asadpour, A. PDF N/A Effective connectivity predicts distributed neural coding of perceptual decision confidence, uncertainty and speed
描述早产儿和足月婴儿在睡眠期间脑活动的时间动态和成熟特征:一项基于EEG微状态的研究。 Adibpour, P. PDF N/A Characterizing the temporal dynamics and maturation of brain activity during sleep: an EEG microstate study in preterm and full-term infants.
SERBP1与PARP1相互作用,并存在于依赖于PARylation的蛋白质复合物中,这些复合物调控剪接、细胞分裂和核糖体生物发生。 Breunig, K. PDF N/A SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis
在运动神经元退化的鼠模型中,脊髓微循环经历了多相的稳态补偿。 Nascimento, F. PDF N/A Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration
与怀疑者相比,超自然信仰者在联合视觉搜索中更快但更不准确地拒绝目标的存在。 Akbari, F. PDF N/A Paranormal believers are quicker but less accurate in rejecting the presence of the target in conjunction visual search compared to skeptics
TRMT1L催化的酪氨酸tRNA上的m22G27对于在氧化应激下实现高效的mRNA翻译和细胞存活是必需的。 Hwang, S.-P. PDF N/A TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress.
全基因组关联分析生长速率在波动和极端温度下的变化 Räsänen, E. PDF N/A Genome-wide association mapping for growth rate at fluctuating and extreme temperatures
有丝分裂期间PI(3,5)P2的不对称性对于不对称液泡遗传至关重要 Huda, M. PDF N/A PI(3,5)P2 asymmetry during mitosis is essential for asymmetric vacuolar inheritance
从蛋白质序列信息设计不同长度的线性和环状肽结合剂 Li, Q. PDF N/A Design of linear and cyclic peptide binders of different lengths from protein sequence information
使用Gibbs采样和edgeR v4进行更快更准确的差异转录表达评估 Baldoni, P. L. PDF N/A Faster and more accurate assessment of differential transcript expression with Gibbs sampling and edgeR v4
Dclk1基因表达的调控网络分析揭示了一个簇细胞-ILC2轴,该轴抑制胰腺肿瘤进展。 Valenti, G. PDF N/A Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression
一罐蠕虫:估算全球蚯蚓物种数量 Decaens, T. PDF N/A A can of worms: estimating the global number of earthworm species
与糖尿病和糖尿病肾病相关的尿液微生物群:系统综述 Graells, T. PDF N/A The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review
核孔蛋白Nup153将剪接机制锚定在核孔上,以实现高效的mRNA加工 De Castro, I. PDF N/A Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing
与满江红(Azolla filiculoides)共培养的水稻植株改变了根系结构和发育阶段的时机 Cannavo', S. PDF N/A Co-cultivating rice plants with Azolla filiculoides modifies root architecture and timing of developmental stages
自上而下的反馈至关重要:类脑连接模式对视听整合的功能影响 Tugsbayar, M. PDF N/A Top-down feedback matters: Functional impact of brainlike connectivity motifs on audiovisual integration
海马长轴功能特化受成年寿命影响 Bowman, C. PDF N/A Adult lifespan effects on functional specialization along the hippocampal long axis
开发具有广泛治疗潜力的临床可行非肌肉肌球蛋白II小分子抑制剂 Radnai, L. PDF N/A Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential
在肝硬化肝脏中进行纯化的梭菌胶原酶间质输注可迅速减少纤维化,且肝毒性最小。 Leaker, B. D. PDF N/A Interstitial infusion of purified collagenase Clostridium histolyticum in the cirrhotic liver causes rapid reduction in fibrosis with minimal liver toxicity
货物适配器身份控制动力蛋白激活的机制和动力学 Gillies, J. P. PDF N/A Cargo adaptor identity controls the mechanism and kinetics of dynein activation
胰岛素抵抗性肥胖中的血浆外泌体加剧三阴性乳腺癌的进展 Llevenes, P. PDF N/A Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer
阿波罗:一种综合性的基于GPU的主机内模拟器,用于模拟病毒进化和感染动力学,涵盖群体、组织和细胞层面。 Perera, D. PDF N/A Apollo: A comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell
口服避孕药对大脑网络的影响:一项重复和扩展研究 Haase, G. PDF N/A Effects of oral contraceptive pills on brain networks: A replication and extension
基准测试用于抗体设计的生成模型 Ucar, T. PDF N/A Benchmarking Generative Models for Antibody Design
食物纳米材料引起的肠道屏障破坏的不良结局路径。 Stanco, D. PDF N/A An Adverse Outcome Pathway for Food Nanomaterial-induced Intestinal Barrier Disruption.
沉浸于自然环境可减弱机械性继发性痛觉过敏的发展:岛叶-丘脑有效连接的作用 Medina, S. PDF N/A Immersion in nature attenuates the development of mechanical secondary hyperalgesia: a role for insulo-thalamic effective connectivity
结直肠癌淋巴结转移相关肠道菌群的鉴定及预测机器学习模型构建 Wu, Y. PDF N/A Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer
循环微小RNA作为慢性肾脏病及其与非透析患者肾脏和心血管结局关联的生物标志物 Ramil - Gomez, O. PDF N/A Circulating microRNAs as biomarkers of chronic kidney disease and its association with renal and cardiovascular outcomes in non-dialysis patients
利用已知的出生情况来解释北冰洋露脊鲸种群估计中的标记延迟 Linden, D. W. PDF N/A Using known births to account for delayed marking in population estimation of North Atlantic right whales
“混合群”的模糊性:现有研究中定义和应用的不一致性 Campbell, J. N. PDF N/A The ambiguity of "hybrid swarm": inconsistent definitions and applications in existing research
人口结构限制了从森林树木的基因组预测和全基因组关联研究中得出的推论。 Slavov, G. T. PDF N/A Population structure limits inferences from genomic prediction and genome-wide association studies in a forest tree
构建用于采集小肠内容物样本的胶囊的逐步方法 Ollagnier, C. PDF N/A Step-by-step methodology for building a capsule to sample small intestine content
去伪存真:结构MRI图像质量评估中的偏差 Provins, c. PDF N/A Defacing biases visual quality assessments of structural MRI
单细胞ATAC-seq数据的多模态整合能够高度准确地描绘出临床相关的肿瘤细胞亚群。 Xiong, K. PDF N/A Multimodal integration of single cell ATAC-seq data enables highly accurate delineation of clinically relevant tumor cell subpopulations
系统挖掘肠道微生物组生物标志物用于炎症性肠病 Yuchen, Z. PDF N/A Systematic Mining of gut microbiota biomarkers for IBD
已发表的兔核糖体rRNA序列中的不一致性:关于序列和位点编号统一性的建议 De, S. PDF N/A Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering
利用肿瘤-免疫动力学综合模型预测慢性髓性白血病患者的无治疗缓解结果 Fassoni, A. C. PDF N/A Predicting treatment-free remission outcomes in Chronic Myeloid Leukemia patients using an integrated model of tumor-immune dynamics
结构和功能证据支持将小鼠的高级视觉区域重新定义为单一的V2区域。 Rowley, D. P. PDF N/A Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2
纤维肌痛患者存在与疾病症状严重程度和抗卫星胶质细胞IgG抗体相关的脂质浓度改变。 Jakobsson, J. E. PDF N/A Fibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies
焦虑/抑郁个体在认知冲突编码过程中表现出前额叶-颞叶同步性紊乱 Shekara, A. PDF N/A Anxious/depressed individuals exhibit disrupted frontotemporal synchrony during cognitive conflict encoding
皮层阿尔法节律从自然场景背景中插值被遮挡的运动 Yeh, L.-C. PDF N/A Cortical alpha rhythms interpolate occluded motion from natural scene context
AB5枯草杆菌溶素细胞毒素诱导的ISR通过STING激活驱动pDCs中IFN-I的表达 Pierre, P. PDF N/A Induction of the ISR by AB5 subtilase cytotoxin drives IFN-I expression in pDCs via STING activation
HighALPS:在Illumina NextSeq和NovaSeq平台上进行超高通量标记基因扩增子文库制备与测序 Flörl, L. PDF N/A HighALPS: Ultra-High-Throughput Marker-Gene Amplicon Library Preparation and Sequencing on the Illumina NextSeq and NovaSeq Platforms
利用遗传和表观遗传筛选方法,将候选因果自身免疫变异与人类原代T细胞网络相联系。 Ho, C.-H. PDF N/A Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells.
禾草等长穗(Alopecurus aequalis)的染色体规模基因组组装与从头注释。 Wright, J. PDF N/A Chromosome-scale genome assembly and de novo annotation of Alopecurus aequalis.
三叶草复合体中重复的靶心图案减少的遗传基础 Yeo, M. T. S. PDF N/A The genetic basis of replicated bullseye pattern reduction across the Trionum Complex
性别特异性:体力活动强度和剂量对BOLD-fMRI脑血管反应性和脑脉动性的影响 Potvin-Jutras, Z. PDF N/A Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility
高分辨率的黑色素皮质素-4受体深度突变扫描为药物发现提供了目标特征 Howard, C. J. PDF N/A High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
利用基于成像的分子记录技术重构单细胞信号传导历史 Hao, K. PDF N/A Reconstructing signaling history of single cells with imaging-based molecular recording
生物分子自适应控制器设计以恢复持续的周期性行为 Britto Bisso, F. PDF N/A Design of a biomolecular adaptive controller to restore sustained periodic behavior
基础成纤维细胞生长因子有助于保护面部神经细胞在冷冻诱导的瘫痪模型中 Iwata, S. PDF N/A Basic fibroblast growth factor helps protect facial nerve cells in a freeze-induced paralysis model
猕猴和人胎盘类器官的比较分析突显了胎盘形成中的进化差异 Caldwell, A. PDF N/A Comparative analysis of rhesus macaque and human placental organoids highlights evolutionary differences in placentation
通过锌指抑制因子驱动的表观遗传沉默,增强CAR-T细胞和TILs中免疫检查点和TGFBR2的抗肿瘤活性 David, M. PDF N/A Enhanced anti-tumor activity by Zinc Finger Repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs
TGFβ1-TNFα调控的中性粒细胞趋化因子分泌与乳腺癌细胞的上皮-间质转化无关 Sengupta, S. PDF N/A TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells
绘制乳腺癌的时间景观:利用表观遗传熵 Monyak, D. L. PDF N/A Mapping the Temporal Landscape of Breast Cancer Using Epigenetic Entropy
精选癌症细胞图谱:全面解析肿瘤在单细胞分辨率下的特征 Tyler, M. PDF N/A The Curated Cancer Cell Atlas: comprehensive characterisation of tumours at single-cell resolution
干龟国家公园石珊瑚种类的代谢组学特征显示出种间和种内变异。 Deutsch, J. M. PDF N/A Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation
饲喂水葫芦(Eichhornia crassipes)饲料,无论是否添加商业浓缩物,对热带山羊和绵羊的动物技术性能及盈利能力的影响 Fanta, Y. U. PDF N/A Effects of feeding water hyacinth (Eichhornia crassipes) fodder with or without commercial concentrate on zoo-technical performance and profitability in tropical goats and sheep
通过体外功能细胞集合体绘制突触集合体 Zaccaria, C. PDF N/A Mapping Synaptic Ensembles Through In Vitro Functional Cell Assemblies
噪声中神经语音追踪的SNR、语音可懂度和注意力努力的不同作用 He, X. PDF N/A Distinct roles of SNR, speech Intelligibility, and attentional effort on neural speech tracking in noise
多丝氨酸肽具有毒性,并会加剧小鼠中的tau病理变化。 Van Alstyne, M. PDF N/A Polyserine peptides are toxic and exacerbate tau pathology in mice
三维定量微弹性成像揭示了小鼠卵巢在衰老过程中卵泡和黄体的空间弹性模式的变化。 Jaeschke, A. PDF N/A Three-dimensional quantitative micro-elastography reveals alterations in spatial elasticity patterns of follicles and corpora lutea in murine ovaries during ageing
一种新烟碱类杀虫剂导致熊蜂组织特异性基因表达变化 Witwicka, A. PDF N/A A neonicotinoid pesticide causes tissue-specific gene expression changes in bumble bees
神秘浇水壶贝的基因组揭示了活体吸盘锚的适应性 Sigwart, J. PDF N/A Genome of the enigmatic watering-pot shell reveals adaptations of a living suction anchor
ReAct项目:分析来自23个不同实验室的数据,以表征在两组活动水平命题下的DNA恢复情况 Gill, P. PDF N/A The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions
一种保守转录因子结合位点图谱揭示了开花植物的细胞类型解析基因调控景观 Baumgart, L. A. PDF N/A An atlas of conserved transcription factor binding sites reveals the cell type-resolved gene regulatory landscape of flowering plants
公开的RNA-seq数据并不能全面代表全球人类的多样性。 Gallego Romero, I. PDF N/A Public RNA-seq data are not representative of global human diversity
耐热的阿拉伯鳉鱼(Aphanius dispar)作为一种新型感染模型,用于研究人类真菌病原体 Minhas, R. PDF N/A The thermotolerant Arabian killifish, Aphanius dispar, as a novel infection model for human fungal pathogens
蜜蜂飞行中的群体协调依赖于成对相互作用、反馈规则变化以及深思熟虑的决策。 Faruque, I. PDF N/A Pairwise interactions, feedback rule changes, and deliberative decisions underlie honeybee inflight group coordination
小鼠皮质卒中后的比例恢复 Kalantari, A. PDF N/A Proportional recovery in mice with cortical stroke
繁殖经历促使雄性加州田鼠(Peromyscus californicus)在行为和生理上发生改变。 Colt, M. E. PDF N/A Reproductive experience drives changes in behavior and physiology in male California mice (Peromyscus californicus)
利用深度学习设计新型PHA合成酶 Tenkanen, T. PDF N/A New-to-nature PHA synthase design using deep learning
非侵入式脑机接口控制与人工智能副驾驶 Lee, J. Y. PDF N/A Non-invasive brain-machine interface control with artificial intelligence copilots
一款全面的应用程序,用于解读和可视化KEGG通路和基因本体论的功能分析 Mena, A. R. PDF N/A A Comprehensive App to Interpret and Visualize the Functional Analysis of KEGG Pathways and Gene Ontologies
DigestR是一款开源软件工具,用于可视化由天然蛋白质分解产生的LC-MS蛋白质组学数据。 de Lamache, D. D. PDF N/A DigestR an open-source software tool for visualizing LC-MS proteomics data resulting from natural protein catabolism
vScreenML v2.0:改进的基于结构的虚拟筛选中减少假阳性的人工智能分类技术 Andrianov, G. V. PDF N/A vScreenML v2.0: Improved Machine Learning Classification for Reducing False Positives in Structure-Based Virtual Screening
PROPERMAB:一种利用机器学习进行抗体可开发性计算机预测的综合框架 Li, B. PDF N/A PROPERMAB: an integrative framework for in silico prediction of antibody developability using machine learning
物种丰富度估算的综合评述与评价 Schmitz, J. E. PDF N/A A Comprehensive Review and Evaluation of Species Richness Estimation
聚合物模型结合超分辨率成像和表观基因组测序,阐明表观遗传反应在塑造四维染色质组织中的作用 Vinayak, V. PDF N/A Polymer Model Integrates Super-Resolution Imaging and Epigenomic Sequencing to Elucidate the Role of Epigenetic Reactions in Shaping 4D Chromatin Organization
鲁索利替尼通过泛素-蛋白酶体系统清除CRYAB p.Arg120Gly聚集物 Alizoti, E. PDF N/A Ruxolitinib clears CRYAB p.Arg120Gly aggregates through the ubiquitin-proteasome system
代谢精细调节和心脏细胞因子分泌是果蝇对高脂肪和高糖饮食的适应性反应。 Khamvongsa-Charbonnier, L. PDF N/A Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies
一种新的肌肉收缩离体模型,用于测量肌肉内分泌和旁分泌信号传导 DABADIE, C. PDF N/A A novel ex vivo model of muscle contraction to measure muscle endocrine and paracrine signalling
通过神经元受体进行细菌感应,启动肠道线粒体监测以适应宿主 Liu, H. PDF N/A Bacterial sensing via Neuronal Receptor Initiates Gut Mitochondrial Surveillance for Host Adaptation
经颅超声皮质电路刺激的微观解构 Lemaire, T. PDF N/A Microscopic deconstruction of cortical circuit stimulation by transcranial ultrasound
在感染SIV的恒河猴中,大麻素使基底神经节的miRNA m6A甲基化谱向抗炎表型转变。 Okeoma, C. M. PDF N/A Cannabinoids shift the basal ganglia miRNA m6A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques
纹状体伏隔核通路通过一个厌恶性的Esr1+下丘脑-缰核回路驱动强迫性寻求行为。 Contesse, T. PDF N/A A striosomal accumbens pathway drives compulsive seeking behaviors through an aversive Esr1+ hypothalamic-habenula circuit.
小血管脑病遗传决定因子TRIM47通过NRF2抗氧化系统调控脑稳态 Duplaa, C. PDF N/A Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system
结合计算流体动力学建模和几何形态计量学方法,量化从光片荧光显微镜成像重建的胚胎鸡心脏解剖结构的血流动力学和解剖特征 Giesbrecht, K. PDF N/A A Combined Computational Fluid Dynamics Modeling and Geometric Morphometrics Methods Approach to Quantifying Hemodynamic and Anatomical Features of Embryonic Chick Heart Anatomies Reconstructed from Light Sheet Fluorescence Microscopy Imaging
从木本被子植物的木质部特异性肽前体中衍生出的进化保守的树液肽 Chen, C.-H. PDF N/A Evolutionary conserved sap peptides derived from xylem-specific peptide precursors in woody angiosperms
单细胞整合揭示了炎症性肠病中的化生现象 Oliver, A. J. PDF N/A Single Cell Integration Characterises Metaplasia in Inflammatory Intestinal Diseases
动态屏障调节着粘连蛋白定位和固定占用率下的基因组折叠 Rahmaninejad, H. PDF N/A Dynamic barriers modulate cohesin positioning and genome folding at fixed occupancy
利用高斯过程估计重建的多带成像加速多壳扩散磁共振成像 Ye, X. PDF N/A Accelerated multi-shell diffusion MRI with Gaussian process estimated reconstruction of multi-band imaging
通过磁遗传学工具调控人类T淋巴细胞 Helalat, S. H. PDF N/A Regulating Human T Lymphocytes Through Magnetogenetic Tools
模拟揭示了着陆运动学变量如何影响最高短跑速度:对教练的启示 Haralabidis, N. PDF N/A Simulations reveal how touchdown kinematic variables affect top sprinting speed: implications for coaching
通过多模态学习实现大规模蛋白质数据的递归清洗 Jiang, Z. PDF N/A Recursive Cleaning for Large-scale Protein Data via Multimodal Learning
利用加权蛋白质-蛋白质相互作用网络进行人类必需基因的深度预测 Mehrpou, S. PDF N/A Deep Prediction of Human Essential Genes using Weighted Protein-Protein Interaction Networks
一个基于化合物生物活性谱的扩散模型,用于预测高内涵图像 Cook, S. PDF N/A A diffusion model conditioned on compound bioactivity profiles for predicting high-content images
对来自全球的象草(Cenchrus purpureus)进行全基因组重测序,以探索全球种群结构及控制产量和饲料质量性状的QTL Teshome, A. PDF N/A Whole genome resequencing of a global collection of Napier grass (Cenchrus purpureus) to explore global population structure and QTL governing yield and feed quality traits
SAMPL-seq揭示了人类肠道微生物组中的微米级空间枢纽 Richardson, M. PDF N/A SAMPL-seq reveals micron-scale spatial hubs in the human gut microbiome
关于“快速封盖移除”的科学笔记——一种评估蜜蜂(Apis mellifera)幼虫感染Tropilaelaps mercedesae的方法 Uzunov, A. PDF N/A A scientific note on "Rapid brood decapping" - a method for assessment of honey bee (Apis mellifera) brood infestation with Tropilaelaps mercedesae
解码难以理解的声音:在低信噪比条件下的神经语音追踪 He, X. PDF N/A Decoding the Unintelligible: Neural Speech Tracking in Low Signal-to-Noise Ratios
深度聚焦:一种通过鼻腔途径优化奖赏环路节点深部脑刺激的方法 Guo, Y. PDF N/A DeepFocus: A Transnasal Approach for Optimized Deep Brain Stimulation of Reward Circuit Nodes
亚单位mRNA鸡尾酒疫苗的选择、设计和免疫原性研究:针对特定免疫反应谱的ASFV抗原 Yuan, F. PDF N/A Selection, Design and Immunogenicity Studies of ASFV Antigens for Subunit mRNA Cocktail Vaccines with Specific Immune Response Profiles
鼻内注射血凝素蛋白增强剂可诱导强效的黏膜免疫,并提供针对甲型流感病毒攻击的交叉保护。 Moriyama, M. PDF N/A Intranasal hemagglutinin protein boosters induce robust mucosal immunity and cross-protection against influenza A viral challenge
从具有一个时间戳和多个观测值的生态时间序列中进行因果发现 Bystrova, D. PDF N/A Causal discovery from ecological time-series with one timestamp and multiple observations
在系统发育和生态学上界定的物种库影响了对依赖年龄的灭绝的推断。 Goncalves-Neto, S. PDF N/A Phylogenetically and ecologically delimited species pool affect the inference of age-dependent extinction
一种新发现的苋属植物(Amaranthus palmeri)染色体外环状DNA中的基因组重排,使其同时对草甘膦和草铵膦两种除草剂产生抗性。 Carvalho-Moore, P. PDF N/A A Novel Genomic Rearrangement in the Amaranthus palmeri Extrachromosomal Circular DNA Provides Dual Herbicide Resistance to Glyphosate and Glufosinate
PRC2促进了幼苗萌发过程中从异养到自养的转变 Samo, N. PDF N/A PRC2 facilitates the transition from heterotrophy to photoautotrophy during seedling emergence
早期经历对野生果蝠的觅食行为影响更大,超过了它们原本的行为倾向。 Rachum, A. PDF N/A Early experience affects foraging behavior of wild fruit-bats more than their original behavioral predispositions
海马体与皮层在社交记忆巩固中的相互作用 Park, G. PDF N/A Hippocampal-cortical interactions in the consolidation of social memory
黑猩猩展示中的情境依赖性节奏性 van der Vleuten, B. PDF N/A Context-dependent Rhythmicity in Chimpanzee Displays
利用迁移学习预测蛋白质-小分子相互作用 Wang, J. PDF N/A Leveraging Transfer Learning for Predicting Protein-Small Molecule Interactions
奖励驱动的小脑爬行纤维活动影响神经和行为学习 Jin, S. PDF N/A Reward-driven cerebellar climbing fiber activity influences both neural and behavioral learning
一种针对恒河猴的新型表观遗传时钟揭示了早期生活逆境与表观遗传年龄加速之间的关联 Bronk, G. PDF N/A A novel epigenetic clock for rhesus macaques unveils an association between early life adversity and epigenetic age acceleration
饮酒性依赖地改变小鼠皮层IL-1β突触信号传导和认知行为 Liss, A. PDF N/A Ethanol drinking sex-dependently alters cortical IL-1β synaptic signaling and cognitive behavior in mice
在顶叶和前额叶皮层中,逐步分离运动和认知序列 Doyle, H. PDF N/A Ramping dissociates motor and cognitive sequences in the parietal and prefrontal cortices
刚地弓形虫入侵宿主细胞时,穿孔宿主细胞质膜需要棒状体胞吐作用。 Male, F. PDF N/A Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis
用于自动收集培养细胞时间分辨代谢组学数据的LC-MS系统 Chan, C. C. Y. PDF N/A LC-MS system for automatically collecting time-resolved metabolomics data of cultured cells
退耕还草对土壤原核生物、真菌和原生生物的复杂响应 Tosi, M. PDF N/A Complex responses of soil prokaryotes, fungi and protists to prairie restoration on retired agricultural lands
因果中介中的高维混淆:双重机器学习与正则化偏相关网络的比较研究 Chen, M. PDF N/A High-dimensional confounding in causal mediation: a comparison study of double machine learning and regularized partial correlation network
整合接合元件对SOS反应和同源重组的调控 Garcia Heredia, A. PDF N/A Regulation of the SOS response and homologous recombination by an integrative and conjugative element
染色质环境对DOT1L在雄性生殖细胞基因表达中的影响 Coulee, M. PDF N/A Chromatin Environment-Dependent Effects of DOT1L on Gene Expression in Male Germ Cells
胎儿肝样类器官再现了血液-肝脏微环境发育及人类多能干细胞的多能造血过程 Rezvani, M. PDF N/A Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells
丝状伪足样结构对类固醇释放至关重要 Simon, E. PDF N/A Filopodia-like Structures are Essential for Steroid Release
在人类早期多能性和细胞谱系中,WNT介导的TCF/LEF转录因子基因表达与啮齿动物模型有所不同。 Ross, C. PDF N/A WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm
非洲爪蟾的呼吸系统揭示了四足动物在生长、再生和愈合方面的共同机制 Perry, S. K. PDF N/A The Xenopus respiratory system reveals common tetrapod mechanisms for growth, regeneration and healing
雄性是默认性别:角粪甲虫性别决定级联的功能意义 Mitchell, L. C. PDF N/A Male is the default sex: functional significance of the sex determination cascade in horned dung beetles
实验性短期热浪对野生传粉者在幼虫发育期间的体重增加和存活率产生负面影响。 Woegler, L. PDF N/A Experimental short-term heatwaves negatively impact body weight gain and survival during larval development in a wild pollinator
脊髓祖细胞中CDKN1c/p57kip2低表达促使细胞从增殖性分裂模式向神经发生性分裂模式转变 Mida, B. PDF N/A A low CDKN1c/p57kip2 expression in spinal progenitors drives the transition from proliferative to neurogenic modes of division
一种调控蟑螂卵子发生和胚胎发育的piRNA Gonzalvo, J. PDF N/A A piRNA regulating oogenesis and embryo development in cockroaches
硫蝶翅膀性二态性和鳞片细胞特化的单核转录组学研究 Loh, L. S. PDF N/A Single-nucleus transcriptomics of wing sexual dimorphism and scale cell specialization in sulphur butterflies
一种油菜素内酯受体激酶对于同型孢子蕨类植物Ceratopteris richardii的性别决定是必需的。 Burow, K. M. PDF N/A A brassinosteroid receptor kinase is required for sex determination in the homosporous fern Ceratopteris richardii
Orthrus:迈向进化和功能性的RNA基础模型 Fradkin, P. PDF N/A Orthrus: Towards Evolutionary and Functional RNA Foundation Models
浊度感官方法:来源与水平如何塑造水生光环境与鱼类视觉生态 Garcia, A. PDF N/A A sensory approach to turbidity: How sources and levels shape aquatic light environments and fish visual ecology
R2-D2:模仿《星球大战》机器人揭示了鹦鹉和椋鸟的异种声音模仿能力 Dam, N. C. P. PDF N/A Artoo-Detoo: What imitating a Star Wars droid reveals on allospecific vocal imitation in parrots and starlings
揭示社会认知中的潜在动态:多智能体逆强化学习 Chen, Y. PDF N/A Unveiling the latent dynamics in social cognition with multi-agent inverse reinforcement learning
强迫性应对策略与适应性应对策略的肾上腺素能和巴甫洛夫基础 Chernoff, C. S. PDF N/A Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies
和弦的协和性:三和弦中每个音的半音变化对其感知协和性的影响 Varkevisser, J. PDF N/A The consonance of chords: The effect of subsemitone changes to each of the notes in a trichord on its perceived consonance
X-Tracker:非洲爪蟾蝌蚪视觉回避行为的自动化分析 McKeown, C. R. PDF N/A X-Tracker: Automated Analysis of Xenopus Tadpole Visual Avoidance Behavior
解开苯基琥珀酸合酶的对映选择性机制:通过多尺度建模和动力学研究厌氧烃降解的见解 Szaleniec, M. PDF N/A Unravelling the Enantioselective Mechanism of Benzylsuccinate Synthase: Insights into Anaerobic Hydrocarbon Degradation Through Multiscale Modelling and Kinetics
一种能够合成自身及其互补链的聚合酶核酶 Gianni, E. PDF N/A A polymerase ribozyme that can synthesize both itself and its complementary strand
蛋白质组装的以键为中心的模块化设计 Wang, S. PDF N/A Bond-centric modular design of protein assemblies
利用-配对靶向RF扩散改进蛋白质结合剂设计 Sappington, I. PDF N/A Improved protein binder design using -pairing targeted RFdiffusion
定义K1样杀伤毒素的α域 Coss, S. A. PDF N/A Defining the alpha domains of K1-like killer toxins
使用贝叶斯狄利克雷过程模型建模微生物组与宿主表型之间的关联 Awany, D. PDF N/A Modelling Microbiome Association with Host Phenotypes Using a Bayesian Dirichlet Process Model
多巴胺D2受体对分离斑马鱼鳃中氧感受器的抑制作用 Reed, M. PDF N/A Oxygen chemoreceptor inhibition by dopamine D2 receptors in isolated zebrafish gills
通过超高效液相色谱-四极杆飞行时间质谱(UPLC-QTOF-MS)和气相色谱-串联质谱(GC-MS/MS)分析以及体外生物活性评估,对印度山蚂蝗(Desmodium gangeticum DC.)进行化学特征分析。 Jagtap, M. A. PDF N/A Chemo-Profiling by UPLC-QTOF-MS, GC-MS/MS analysis and In Vitro Bioactivity Assessment of Desmodium gangeticum DC.
味觉处理的演变改变了饮食偏好 Bertolini, E. PDF N/A Evolution of taste processing shifts dietary preference
语义抑制与再激活:从语义理解到审美欣赏的超越——来自审美阅读的fNIRS证据 Liu, H. PDF N/A Semantic Inhibition and Reactivation for Transcending from Semantic Understanding to Aesthetic Appreciation: fNIRS Evidence from Aesthetic Reading
单分子表征:Aducanumab、Lecanemab、Gantenerumab 和 Donanemab 对可溶性β淀粉样蛋白聚集体的结合特性 Fertan, E. PDF N/A Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab
认知需求和听觉噪音对姿势动态的影响 Carey, S. PDF N/A Influence of Cognitive Demand and Auditory Noise on Postural Dynamics
HDAC抑制剂在体外重现了与人类疾病相关的小胶质细胞特征 Haage, V. C. PDF N/A HDAC Inhibitors recapitulate Human Disease-Associated Microglia Signatures in vitro
自闭症谱系障碍啮齿动物模型中依赖于活动的整体内吞作用的趋同性抑制。 Bonnycastle, K. PDF N/A Convergent depression of activity-dependent bulk endocytosis in rodent models of autism spectrum disorders.
在人脑皮层视觉刺激过程中同时定量氧气和葡萄糖消耗 Epp, S. M. PDF N/A Simultaneous quantification of oxygen and glucose consumption during visual stimulation in the human cortex
甘氨酰-tRNA的隔离是一种统一机制,它解释了与GARS1相关的外周神经病变。 Mora, N. PDF N/A Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy
一种图神经网络方法研究神经发育过程中大脑临界状态 Cabral-Carvalho, R. M. PDF N/A A Graph Neural Network Approach to Investigate Brain Critical States Over Neurodevelopment
在阿尔茨海默病敲入模型中早期破坏内嗅皮层的多巴胺 Nakagawa, T. PDF N/A Early disruption of entorhinal dopamine in a knock-in model of Alzheimer's disease
SSRIs对中缝背核5-羟色胺神经元空间转录组的影响 Henningson, C. PDF N/A Effects of SSRIs on the spatial transcriptome of dorsal raphe serotonin neurons
视觉刺激的接近性降低了眼跳后的α波侧化 Turner, C. PDF N/A Proximity to Visual Stimuli Reduces Post-Saccadic Alpha Lateralisation
TENM4是触觉和痛觉传导的重要转导成分。 Khallaf, M. PDF N/A TENM4 is an essential transduction component for touch and pain
亚毫米级扩散磁共振成像:采用平面内分段三维多片采集与去噪器正则化重建 Li, Z. PDF N/A Submillimeter diffusion MRI using an in-plane segmented 3D multi-slab acquisition and denoiser-regularized reconstruction
在几何网络模型中,减少节点的空间扩散能够改善与计算能力提升相关的拓扑结构。 Christiansen, N. PDF N/A Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities
蜜蜂睡眠的神经相关性 Moguilner, S. PDF N/A Neuronal correlates of sleep in honey bees
期望生成及其对后续疼痛和视觉感知的影响 Botvinik-Nezer, R. PDF N/A Expectation generation and its effect on subsequent pain and visual perception
tDCS颅神经协同刺激:揭示大鼠三叉神经直流电刺激涉及的脑干通路 Majdi, A. PDF N/A tDCS Cranial Nerve Co-Stimulation: Unveiling Brainstem Pathways Involved in Trigeminal Nerve Direct Current Stimulation in Rats
图雷特综合症中的丘脑-额叶连接模式:结合颅内深部脑刺激和脑电图记录的见解 Wehmeyer, L. PDF N/A Thalamo-frontal connectivity patterns in Tourette Syndrome: Insights from combined intracranial DBS and EEG recordings
淀粉样前体蛋白(Amyloid Beta Precursor Protein)有助于短命的青绿色鳉鱼(Nothobranchius furzeri)的脑老化和学习能力下降。 de Bakker, D. E. M. PDF N/A Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)
一种用于正电子发射断层扫描成像的μ阿片受体小分子拮抗剂放射性示踪剂。 Plakas, K. PDF N/A A Small-molecule Antagonist Radiotracer for Positron Emission Tomography Imaging of the Mu Opioid Receptor.
纹状体侧向抑制调节左旋多巴诱导的运动障碍小鼠模型中的动作选择 Twedell, E. L. PDF N/A Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia
hMT+活动预测空间注意对周围抑制的影响 Kiniklioglu, M. PDF N/A hMT+ Activity Predicts the Effect Of Spatial Attention On Surround Suppression
大鼠岛叶皮层对刺激引导行为的贡献 Tensaouti, Y. PDF N/A Contribution of rat insular cortex to stimulus-guided action
在稳定注视和主动视觉过程中刺激特征的表征 Moran, C. PDF N/A The representation of stimulus features during stable fixation and active vision
脂质组学分析揭示了散发性帕金森病与GBA突变携带者中共享及独特的病理特征:对疾病机制的启示 Munoz, S. S. PDF N/A Lipidomic Profiling Reveals Shared and Distinct Pathological Signatures in Sporadic Parkinson's Disease and GBA Mutation Carriers: Implications for Disease Mechanisms
物体接触前后皮层抓握相关活动的变化 Yan, Y. PDF N/A Changes in cortical grasp-related activity before and after object contact
成长中的小脑:从婴儿到学龄的脑功能发育 Lyu, W. PDF N/A The Growing Little Brain: Cerebellar Functional Development from Cradle to School
食物摄入会增强海马体中的锋电波-波纹复合体。 Kaya, E. PDF N/A Food intake enhances hippocampal sharp wave-ripples
通过IP1检测,小鼠大脑中5-HT2A受体激活的快照 de la Fuente Revenga, M. PDF N/A Snapshot of 5-HT2A receptor activation in the mouse brain via IP1 detection
Gasdermin D 被激活但在 SOD1G93A 模型中不驱动神经退行性变:针对细胞焦亡的潜在意义 Gunner, G. PDF N/A Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis
光线通过交感神经系统调节葡萄糖和脂质稳态 Chen, X. PDF N/A Light modulates glucose and lipid homeostasis via the sympathetic nervous system
脑部预靶向PET - 利用单克隆抗体成像中枢神经系统靶点的新视野 Gustavsson, T. PDF N/A Brain Pretargeted PET - New Horizons to Image CNS Targets with Monoclonal Antibodies
基于荧光寿命的FRET生物传感器用于监测活细胞中TDP-43的N端结构域相互作用:一种用于ALS和FTD药物发现的新资源 Nathan Kochen, N. PDF N/A Fluorescence lifetime-based FRET biosensors for monitoring N-terminal domain interactions of TDP-43 in living cells: A novel resource for ALS and FTD drug discovery
老年小鼠的平衡表现依赖于单极刷状细胞 Kizeev, G. PDF N/A Balance performance in aged mice is dependent on unipolar brush cells
通过抑制性突触可塑性实现递归神经回路中的结构化稳定 Festa, D. PDF N/A Structured stabilization in recurrent neural circuits through inhibitory synaptic plasticity
基底外侧杏仁核中II组代谢型谷氨酸受体的激活抑制了由辨别性刺激引发的奖赏寻求行为 LeCocq, M. R. PDF N/A Activation of Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Reward Seeking Triggered by Discriminative Stimuli
持续性钠电流在Scn8a功能获得性小鼠中将癫痫与扩散性去极化联系起来 Aiba, I. PDF N/A Persistent Na+ current couples seizure with Spreading depolarization in Scn8a gain-of-function mice
溶栓通过依赖于血管内皮生长因子B(VEGF-B)对脂肪分解的影响,加剧了缺血性卒中后的脑血管损伤。 Nilsson, I. PDF N/A Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis
超越CTCT:特发性震颤患者接受磁共振引导聚焦超声(VIM-MRgFUS)治疗后的远期结构变化 Krauss, J. PDF N/A Beyond the CTCT: Remote Structural Changes After VIM-MRgFUS in Essential Tremor
使用循环机制模型快速、可解释、数据驱动的神经动力学模型 Burghi, T. B. PDF N/A Rapid, interpretable, data-driven models of neural dynamics using Recurrent Mechanistic Models
多站点研究中结构脑网络的协调 Shen, R. S. PDF N/A Harmonization of Structural Brain Networks for Multi-site Studies
使用隐马尔可夫模型表征先天盲人的动态功能连接 Pedersini, C. A. PDF N/A Characterizing dynamic functional connectivity in congenitally blind people using Hidden Markov Models
特定区域的扩散去极化驱动异常的癫痫后行为 Mitlasoczki, B. PDF N/A Region-specific spreading depolarization drives aberrant post-ictal behavior
睡眠结构与阿尔茨海默病病理的区域性关联 Buchal, A. PDF N/A Regional associations of sleep architecture and Alzheimer's disease pathology
前脑岛中的温度感知预测和预测误差 Toussaint, B. PDF N/A Thermoceptive predictions and prediction errors in the anterior insula
通过遗传手段降低翻译抑制因子FMRP和4E-BP2的水平,可以保护阿尔茨海默病小鼠模型的记忆功能。 Campos Ribeiro, F. PDF N/A Genetic reduction of the translational repressors FMRP and 4E-BP2 preserves memory in mouse models of Alzheimer's disease
星形胶质细胞Kir4.1通道在脊髓损伤后痉挛中的功能贡献 Barbay, T. PDF N/A Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injury
多组学特征分析揭示,在Sp4突变小鼠(一种精神分裂症和双相情感障碍的遗传模型)中,全脑突触广泛紊乱,神经元和胶质细胞呈现区域特异性和年龄特异性的变化。 Kwon, M. J. PDF N/A Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in Sp4 mutant mice, a genetic model of schizophrenia and bipolar disorder
RiboTag RNA测序揭示脑缺血后星形胶质细胞终足中HSP70的局部翻译 Shim, B. PDF N/A RiboTag RNA Sequencing Identifies Local Translation of HSP70 In Astrocyte Endfeet After Cerebral Ischemia
嗅觉转导电流的放大实现了稀疏刺激编码 Belonio, K. C. PDF N/A Amplification of olfactory transduction currents implements sparse stimulus encoding
奥罗波切正布尼亚病毒神经感染的特征 Connors, K. A. PDF N/A Characterization of neural infection by Oropouche orthobunyavirus
微流控装置中盘基网柄菌细胞在剪切应力依赖性粘附与运动行为的定量测量 Fakhari, S. PDF N/A Quantitative measurements of shear stress-dependent adhesion and motion of Dictyostelium discoideum cells in a microfluidic device
通过单细胞多组学分析解读小鼠胚胎皮肤中的基因调控程序 Deng, Q. PDF N/A Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis
STAT3信号传导增强了植入后小鼠发育期间的组织扩张 Nichols, J. PDF N/A STAT3 signalling enhances tissue expansion during postimplantation mouse development
基于CRISPR/Cas9的鸟类胚胎体内报告基因敲入 Petit-Vargas, A. PDF N/A CRISPR/Cas9-based somatic knock-in of reporters in the avian embryo in ovo
细胞信号突起在脊髓神经发生中实现动态远距离接触 Hawley, J. PDF N/A Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis
CellMet: 从细胞和组织中提取三维形态学指标 Theis, S. PDF N/A CellMet: Extracting 3D shape metrics from cells and tissues
鉴定果蝇变态过程的特化脂质屏障 Lampe, L. PDF N/A Identification of a specialized lipid barrier for Drosophila metamorphosis
克服倍性障碍:三倍体桥梁在碎米荠属植物遗传渗入中的作用 Bartolic, P. PDF N/A Overcoming ploidy barriers: the role of triploid bridges in the genetic introgression of Cardamine amara
昆虫的基因组预测:以黄蜂Nasonia vitripennis翅膀形态特征为例的研究 Xia, S. PDF N/A Genomic prediction in insects: a case study on wing morphology traits in the jewel wasp Nasonia vitripennis
在模糊地形中自由觅食的猕猴重视信息 Shahidi, N. PDF N/A Freely foraging macaques value information in ambiguous terrains
在啮齿动物径向迷宫任务中,前额叶对回顾性空间工作记忆的表征 Taliaferro, J. P. PDF N/A Prefrontal representations of retrospective spatial working memory in a rodent radial maze task
当对手不在时:雄性蓝鳍鳉对雌性的攻击行为 Karatgi, R. PDF N/A When Rivals Are Absent: Male Aggression Towards Females in Bluefin Killifish
全流程三维电化学微胶囊封装类器官自动化高通量筛选平台加速罕见病药物研发 Xu, Z. PDF N/A Whole-Process 3D ECM-Encapsulated Organoid-Based Automated High-Throughput Screening Platform Accelerates Drug Discovery for Rare Diseases
复杂多途径反应动力学分析:胰岛素二聚体解离 Jeong, K. PDF N/A Analysis of the dynamics of a complex, multipathway reaction: Insulin dimer dissociation
脊髓脑脊液接触神经元是沿小鼠脊髓分布的一种保守的感觉神经元群体。 CROZAT, E. PDF N/A Spinal cerebrospinal fluid contacting neurons are a conserved sensory neuronal population along the mouse spinal cord
人类内侧颞叶中记忆形成与回忆之间时间顺序的神经编码得以保留 Khazali, M. F. PDF N/A A preserved neural code for temporal order between memory formation and recall in the human medial temporal lobe
Dnajc3(HSP40)调节小鼠视神经的轴突再生 Wang, J. PDF N/A Dnajc3 (HSP40) Modulates Axon Regeneration in the Mouse Optic Nerve
改进的螺旋神经节神经元的光遗传学修饰,用于未来的光学耳蜗植入 Thirumalai, A. PDF N/A Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants
估计平均值:时间间隔摘要表征的行为和神经相关性 Otsuka, T. PDF N/A Estimating the mean: behavioral and neural correlates of summary representations for time intervals
掘土水鼠犁鼻器的神经解剖学 Ruiz-Rubio, S. PDF N/A Neuroanatomy of the Accessory Olfactory Bulb in the Fossorial Water Vole
预融合AAA+重塑目标-SNARE蛋白复合物能够实现突触传递 White, K. I. PDF N/A Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission
人脑视觉皮层中的行波:基于模型的MEG-EEG方法 Grabot, L. PDF N/A Traveling Waves in the Human Visual Cortex: a MEG-EEG Model-Based Approach
在Srrm2小鼠中,一种精神分裂症和神经发育障碍的遗传模型,观察到SynGAP-γ的减少、Agap3剪接的破坏以及少突胶质细胞的缺陷。 Aryal, S. PDF N/A Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder
斑马鱼幼鱼中脚间核的解剖和功能组织 Wu, Y. K. PDF N/A Anatomical and functional organization of the interpeduncular nucleus in larval zebrafish
星形胶质细胞的区域特化是由出生后的发育过程塑造的。 Schroeder, M. E. PDF N/A Astrocyte regional specialization is shaped by postnatal development
在自然伸手过程中猕猴前运动皮层神经元的手部位置场 Cao, S. PDF N/A Hand Position Fields of Neurons in the Premotor Cortex of Macaques during Natural Reaching
钾通道亚基Kcnn1在神经元中的过度表达延长了SOD1相关ALS和A53T α-突触核蛋白小鼠模型的生存期 Nagy, M. PDF N/A Neuronal overexpression of potassium channel subunit Kcnn1 prolongs survival of SOD1-linked ALS and A53T alpha-synuclein mouse models
可卡因的摄入和渴求在多巴胺神经元中产生不同的转录组特征 Pollock, T. A. PDF N/A Cocaine taking and craving produce distinct transcriptional profiles in dopamine neurons
在蝗虫中,衰老会减缓去极化扩散的恢复,而抗氧化剂治疗则会加速其恢复。 Robertson, M. PDF N/A Recovery from Spreading Depolarization is slowed by aging and accelerated by antioxidant treatment in locusts
实时预测和相位靶向脑振荡 Jongejan, S. L. PDF N/A Predicting and phase targeting brain oscillations in real-time
深度生成网络揭示了颞下皮层(IT)神经元的调谐特性,并预测了它们对视觉感知的影响。 Papale, P. PDF N/A Deep generative networks reveal the tuning of neurons in IT and predict their influence on visual perception
空间转录组学与免疫荧光染色的整合揭示了实验性胶质母细胞瘤中星形胶质细胞的空间异质性和可塑性 Ghosh, M. PDF N/A Integration of spatial transcriptomics with immunofluorescence staining reveals spatial heterogeneity and plasticity of astrocytes in experimental glioblastomas
星形胶质细胞中HIV-1 Nef的表达降低了伏隔核中谷氨酸转运蛋白的表达,并增加了大鼠的可卡因寻求行为。 Pla-Tenorio, J. PDF N/A Astrocytic HIV-1 Nef expression decreases glutamate transporter expression in the nucleus accumbens and increases cocaine-seeking behavior in rats
光学相干断层扫描能够对中风病变中的细胞移植引导重塑进行纵向评估。 Adewumi, H. O. PDF N/A Optical coherence tomography enables longitudinal evaluation of cell graft-directed remodeling in stroke lesions
阿尔茨海默病中线粒体功能障碍是由患者来源神经元中过量的内质网钙释放驱动的 Mustaly-Kalimi, S. PDF N/A Mitochondrial Dysfunction in Alzheimer's Disease Is Driven By Excess ER-Calcium Release in Patient-Derived Neurons
大细胞、小细胞和视锥细胞通路中空间总和的特征 Wu, C. S. PDF N/A Characteristics of spatial summation in the magnocellular, parvocellular, and koniocellular pathways
黑皮质素4受体依赖的ACTH机制在预防早期生活癫痫后的焦虑样行为和正常化星形胶质细胞蛋白中的作用 Khalife, M. R. PDF N/A Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins After Early Life Seizures
人类可卡因使用障碍中腹侧纹状体的多组学和细胞类型特异性特征 Zillich, E. PDF N/A A multi-omics and cell type-specific characterization of the ventral striatum in human cocaine use disorder
重新编程的人侧脑室旁隆起前体细胞生成纹状体神经元并在亨廷顿病大鼠模型中恢复运动功能。 McCaughey-Chapman, A. PDF N/A Reprogrammed Human Lateral Ganglionic Eminence Precursors Generate Striatal Neurons and Restore Motor Function in a Rat Model of Huntington's Disease.
小脑攀爬纤维传递灵活、快速适应的奖励预测信号 Vignali, C. PDF N/A Cerebellar climbing fibers signal flexible, rapidly adapting reward predictions
沿着不同视觉通路学习的独特的皮层空间表征 Lian, Y. PDF N/A Distinct cortical spatial representations learned along disparate visual pathways
人类的BNST体积并非仅仅是两性异形的。 Berry, S. C. PDF N/A Human BNST volume is not simply sexually dimorphic
上下文依赖偏好中重复的作用 Wagner, B. J. PDF N/A The role of repetition in context-dependent preference
外周给药的TNF抑制剂对α-突触核蛋白诱导的大鼠多巴胺能神经元死亡无保护作用 Christiansen, J. R. PDF N/A Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats
RIPK2对于小胶质细胞对细菌胞壁酰二肽的炎症反应至关重要,但对脂多糖的炎症反应则不然。 Yang, C. PDF N/A RIPK2 is crucial for the microglial inflammatory response to bacterial muramyl dipeptide but not to lipopolysaccharide
AML体内靶向的整合型scFv鉴定与CAR T细胞生成 Müller-Tidow, C. PDF N/A Integrated scFv identification and CAR T cell generation for AML targeting in vivo
通过降解糖免疫检查点Siglec-7和-9来重塑肿瘤微环境 Wang, C. PDF N/A Reshaping the tumor microenvironment by degrading glycoimmune checkpoints Siglec-7 and -9
在拟南芥转座元件中揭示的DNA甲基化与H3K27me3之间的全新串扰 Hure, V. PDF N/A Novel crosstalk between DNA methylation and H3K27me3 revealed at Arabidopsis transposable elements
map3k1抑制了迁移性眼原基在涡虫再生中的终末分化 Lo, K. C. PDF N/A map3k1 suppresses terminal differentiation of migratory eye progenitors in planarian regeneration
在家族性肌萎缩性侧索硬化症4型中,对显性SETX突变进行等位基因特异性沉默 Winkelsas, A. PDF N/A Allele-specific silencing of a dominant SETX mutation in familial amyotrophic lateral sclerosis type 4
新皮层分化与海马体对无意义物品及其空间位置的整合 Nemecz, Z. PDF N/A Neocortical differentiation and hippocampal integration of non-meaningful items and their spatial location

medRxiv

标题 作者 PDF链接 代码仓库 Title
在线46:老年人群的在线认知评估——以英国1946年出生队列为例 Cai, Z. PDF N/A Online46: online cognitive assessments in elderly cohorts - the British 1946 birth cohort case study
比较神经调节靶点以减少吸烟渴望和戒断症状:一项随机临床试验 Petersen, N. PDF N/A Comparing neuromodulation targets to reduce cigarette craving and withdrawal: A randomized clinical trial
可穿戴式感知在饮食事件监测中的应用:系统性综述协议的更新 Zhou, J. PDF N/A Wearable Sensing in Eating Episode Monitoring: An Updated Systematic Review Protocol
探索撒哈拉以南非洲地区人乳头瘤病毒疫苗接种率低的多重决定因素及干预措施:范围综述协议 KAILEMIA, P. N. PDF N/A Exploring intersectional determinants of, and interventions for, low uptake of human papillomavirus vaccine in Sub-Saharan Africa: A scoping review protocol
巴西东北部传统基隆博拉社区中对人类乳头瘤病毒的认知与感知 Campos, M. R. PDF N/A KNOWLEDGE AND PERCEPTION ABOUT HUMAN PAPILLOMAVIRUS IN TRADITIONAL QUILOMBOLA COMMUNITIES IN NORTHEAST BRAZIL
流感病毒在生牛奶中的传染性和持久性 Zulli, A. PDF N/A Infectivity and persistence of influenza viruses in raw milk
美国中年及老年人群中大麻使用的流行病学 Livne, O. PDF N/A Epidemiology of Cannabis Use Among Middle-Aged and Older Adults in the United States
室内空气无目标病毒宏基因组学作为一种新型监测工具用于呼吸、肠道和皮肤病毒 Karatas, M. PDF N/A Untargeted viral metagenomics of indoor air as a novel surveillance tool for respiratory, enteric and skin viruses
感染并不相同:个体易感性和传播性之间的协变对流行病动态的影响 Harris, J. D. PDF N/A Infections are not alike: the effects of covariation between individual susceptibility and transmissibility on epidemic dynamics
新型数字化培训包增强基层医疗从业者临床共情与现实乐观沟通能力的可行性试验 Bishop, F. L. PDF N/A Feasibility trial of a new digital training package to enhance primary care practitioners' communication of clinical empathy and realistic optimism
学术家庭医学教员倦怠的预测因素:回顾过去,规划未来 Antao, V. PDF N/A Predictors of Burnout Among Academic Family Medicine Faculty: Looking Back to Plan forward
了解终端用户对手部卫生启用技术的偏好:一项在卢萨卡郊区进行的混合方法研究 Kazimbaya, K. PDF N/A Understanding end-user preferences for hand hygiene enabling technologies: a mixed-methods study in peri-urban Lusaka
N-乙酰左旋亮氨酸在成人和儿科尼曼-皮克病C型患者中的疾病修饰和神经保护作用 Patterson, M. C. PDF N/A Disease Modifying, Neuroprotective Effect of N-acetylLleucine in Adult and Pediatric Patients with Niemann Pick disease type C
妊娠期糖尿病孕妇中胎盘炎症的一些标志物 De Luccia, T. P. d. B. PDF N/A Some markers of placental inflammation in pregnant women with gestational diabetes
剖析谵妄的遗传和蛋白质组学风险因素 Raptis, V. PDF N/A Dissecting the genetic and proteomic risk factors for delirium
基因变异类型和位置与一般人群中乳腺癌风险的相关性 Akamandisa, M. P. PDF N/A Association of Gene Variant Type and Location with Breast Cancer Risk in the General Population
准确初始出院计划和住院期间转诊对出院延误的影响:一项回顾性队列研究 Burns, D. PDF N/A Impact of accurate initial discharge planning and in-patient transfers of care on discharge delays: a retrospective cohort study
高剂量与标准剂量流感疫苗在预防住院方面的相对有效性:法国2022/23季节全国回顾性队列研究 Bricout, H. PDF N/A Relative effectiveness of high-dose vs standard-dose influenza vaccines in preventing hospitalizations: a national retrospective cohort study in France, 2022/23 season