| 愿意等待与内源性皮质醇的变化有关。 |
Lukinova, E. |
PDF |
N/A |
Willingness to wait covaries with endogenous variation in cortisol |
| 选择性提取通过脑电图（EEG）神经模式的重现得以揭示。 |
Moccia, A. |
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N/A |
Selective retrieval revealed by electroencephalographic (EEG) neural pattern reinstatement |
| 从英国医院分离出的肠外大肠杆菌（ExPEC）菌株中的毒力因子。 |
Turton, J. F. |
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N/A |
Virulence factors among isolates of extraintestinal Escherichia coli (ExPEC) from hospitals in the United Kingdom. |
| 从非靶向代谢组学中识别和整合关键代谢反应 |
Köhler, N. |
PDF |
N/A |
Identification and Integration of Key-Metabolic Reactions from Untargeted Metabolomics |
| 人类在行走时利用了横向稳定性和机动性之间的权衡 |
Kulkarni, R. N. |
PDF |
N/A |
Humans Exploit the Trade-Off Between Lateral Stability and Manoeuvrability During Walking |
| GEF和GAP对Cdc42 GTPase循环的寡聚依赖性和协同调控 |
Tschirpke, S. |
PDF |
N/A |
Oligomerization-dependent and synergistic regulation of Cdc42 GTPase cycling by a GEF and a GAP |
| 通过CRISPR/Cas9工程改造人类间充质干细胞系实现细胞外基质的组成性编辑 |
Prithiviraj, S. |
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N/A |
Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines |
| 在伤害感受器中表达的钠通道对动作电位的阈下相、上升支和肩部有不同的贡献。 |
Köster, P. A. |
PDF |
N/A |
Sodium channels expressed in nociceptors contribute distinctly to action potential subthreshold phase, upstroke and shoulder |
| ATP爆发是分枝杆菌抗生素致死性的主要驱动力 |
Lodhiya, T. |
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N/A |
ATP burst is the dominant driver of antibiotic lethality in Mycobacteria |
| 在观看自然电影时，神经同步性表现出韧性驱动 |
Ye, S. |
PDF |
N/A |
Resilience-driven neural synchrony during naturalistic movie watching |
| 在分化和癌症过程中，全球染色质重塑及对具有特定进化年龄基因的调控 |
Raynal, F. |
PDF |
N/A |
Global chromatin reorganization and regulation of genes with specific evolutionary ages during differentiation and cancer |
| 使用DeepScence进行单细胞和空间衰老细胞检测 |
Qu, Y. |
PDF |
N/A |
Single-cell and spatial detection of senescent cells using DeepScence |
| 植物细胞质膜桥通过内质网驱动的非完全胞质分裂形成 |
Li, Z. P. |
PDF |
N/A |
Plant plasmodesmata bridges form through ER-driven incomplete cytokinesis |
| 全脑任务调制功能连接方法在fMRI任务连接组学中的比较 |
Masharipov, R. |
PDF |
N/A |
Comparison of whole-brain task-modulated functional connectivity methods for fMRI task connectomics |
| 分子密度调控的结合位点成熟机制介导了Ndc80与着丝粒受体CENP-T的结合 |
Tarasovetc, E. V. |
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N/A |
Binding Site Maturation Modulated by Molecular Density Underlies Ndc80 Binding to Kinetochore Receptor CENP-T |
| 使用压缩光场显微镜对体内动态进行千赫兹体积成像 |
Wang, Z. |
PDF |
N/A |
Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy |
| 固有无序的RNA结合基序协同作用以催化RNA折叠并驱动相分离 |
Niedner-Boblenz, A. |
PDF |
N/A |
Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation |
| 自主唤醒的变异介导了空白思维事件的可报告性 |
Boulakis, P. A. |
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N/A |
Variations of autonomic arousal mediate the reportability of mind-blanking occurrences |
| 一种良好的相互作用动力平衡引导转录因子枢纽向基因方向移动 |
Fallacaro, S. |
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N/A |
A fine kinetic balance of interactions directs transcription factor hubs to genes |
| 在羊膜动物原肠胚形成过程中，左右组织者形成之前，双侧细胞流动呈现出不对称性。 |
Asai, R. |
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N/A |
Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation |
| 植物肉和动物肉的机械和感官特征 |
St. Pierre, S. R. |
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N/A |
The mechanical and sensory signature of plant-based and animal meat |
| 突触富集与同一神经元内两种对立多巴胺受体的动态调控 |
Hiramatsu, S. |
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N/A |
Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons |
| 多层次不可逆性揭示了人类大脑动力学中非平衡相互作用的高阶组织 |
Nartallo-Kaluarachchi, R. |
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N/A |
Multilevel irreversibility reveals higher-order organisation of non-equilibrium interactions in human brain dynamics |
| 三相血栓形成模型：B型主动脉夹层的计算研究 |
Gupta, I. |
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N/A |
Triphasic Thrombosis Model: A Computational Study of Type B Aortic Dissection |
| 蜂鸟传粉的趋同进化导致通过基因下调反复丧失花香 |
Darragh, K. |
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N/A |
The convergent evolution of hummingbird pollination results in repeated floral scent loss through gene downregulation |
| 同时捕食多个猎物：功能反应线性关系的频率和种群动态效应 |
Novak, M. |
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N/A |
Feeding on multiple prey at a time:The frequency and population-dynamic effects of functional-response linearity |
| 心脏肌钙蛋白T内源性无序连接区的结构动力学 |
Cubuk, J. |
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N/A |
Structural dynamics of the intrinsically disordered linker region of cardiac troponin T |
| 南极地热土壤中表现出缺乏区域性栖息地泛化微生物 |
Noell, S. E. |
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N/A |
Antarctic geothermal soils exhibit an absence of regional habitat generalist microorganisms |
| 一个组成性异染色质区域塑造了基因组组织并影响神经孢子菌的基因表达 |
Reckard, A. T. |
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N/A |
A Constitutive Heterochromatic Region Shapes Genome Organization and Impacts Gene Expression in Neurospora crassa |
| 利用一种新颖的纤维追踪方法，研究从婴儿期到青春期上行听觉通路微观结构成熟的空间组织 |
Lynch, K. M. |
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N/A |
The spatial organization of ascending auditory pathway microstructural maturation from infancy through adolescence using a novel fiber tracking approach |
| 鉴定枯草芽孢杆菌萌发受体蛋白GerAB中参与孢子吸水的关键残基 |
Chen, L. |
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N/A |
Identification of key residues in Bacillus subtilis germinant receptor protein GerAB involved in spore water uptake |
| KATMAP：从敲低数据推断剪接因子活性及调控靶点 |
McGurk, M. P. |
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N/A |
KATMAP: Inferring splicing factor activity and regulatory targets from knockdown data |
| 学习进度表与教学的共同演化，不仅促进了知识的累积，还催生了一种教师创新综合症 |
Maisonneuve, L. |
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N/A |
The coevolution of learning schedules and teaching enhances cumulative knowledge and drives a teacher-innovator syndrome |
| ATG5的非经典作用及膜ATG8化在retromer组装和功能中的作用 |
Paddar, M. A. |
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N/A |
Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function |
| 一种用于筛选体内蛋白水解开关的方法，这些开关能够介导Notch激活 |
Baker, F. |
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N/A |
An in vivo screen for proteolytic switches that can mediate Notch activation |
| 在样地和植物水平上增加植物化学多样性对节肢动物群落有影响。 |
Ojeda-Prieto, L. |
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N/A |
Increasing intraspecific plant chemical diversity at plot and plant level affects arthropod communities |
| 通过脑电图的不规则成分评估慢性疼痛中兴奋与抑制的平衡 |
Gil Avila, C. |
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N/A |
Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG |
| 力化学力调控停滞新生链的组成和命运 |
Khan, D. |
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N/A |
Mechanochemical forces regulate the composition and fate of stalled nascent chains |
| 利用光遗传学技术对肌动蛋白细胞骨架和片足形成中的膜结构进行低温电子断层扫描 |
Inaba, H. |
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N/A |
Cryo-ET of actin cytoskeleton and membrane structure in lamellipodia formation using optogenetics |
| FusionESP：通过融合蛋白质和化学知识，提升酶-底物配对预测的改进方法 |
Du, Z. |
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N/A |
FusionESP: Improved enzyme-substrate pair prediction by fusing protein and chemical knowledge |
| 失眠评分：失眠的预测能力，对癌症具有高诊断和预后价值。 |
Dan, X. |
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N/A |
Insomnia score: predictive ability of insomnia, high-diagnostic and prognostic value for cancer. |
| 不同血清型3肺炎链球菌中转化频率与感受态基因表达的变异 |
Shambhu, S. |
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N/A |
Variation in transformation frequency and competence gene expression among serotype 3 Streptococcus pneumoniae |
| 学习是行为个体性的基本来源。 |
Manna, R. |
PDF |
N/A |
Learning is a fundamental source of behavioral individuality |
| 脑尺度：在脉冲神经网络中实现可扩展的在线学习 |
Wang, C. |
PDF |
N/A |
BrainScale: Enabling Scalable Online Learning in Spiking Neural Networks |
| 用于光刺激和电生理记录的铸造双色纳米光子神经探针 |
Roszko, D. A. |
PDF |
N/A |
Foundry-fabricated dual-color nanophotonic neural probes for photostimulation and electrophysiological recording |
| 番茄中角黄素/玉米黄质合酶的表达改变了类胡萝卜素库，增强了维生素A原和风味挥发性物质 |
Fu, J. |
PDF |
N/A |
Capsanthin/Capsorubin Synthase Expression in Tomato Alters Carotenoid Pools, Enhancing Provitamin A and Flavor Volatiles |
| FIGL1限制了拟南芥中减数分裂非交换事件的形成 |
Charif, D. |
PDF |
N/A |
FIGL1 limits the formation of meiotic non crossover events in Arabidopsis thaliana |
| 婴儿开放大脑：一个婴儿脑部分割的开源仓库 |
Feczko, E. J. |
PDF |
N/A |
Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations |
| E(Q)AGNN-PPIS：用于蛋白质-蛋白质相互作用位点预测的注意力增强等变图神经网络 |
Animesh, |
PDF |
N/A |
E(Q)AGNN-PPIS: Attention Enhanced Equivariant Graph Neural Network for Protein-Protein Interaction Site Prediction |
| 急性GARP耗竭会破坏囊泡运输，导致分拣、分泌和O-糖基化出现严重缺陷。 |
Khakurel, A. |
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N/A |
Acute GARP depletion disrupts vesicle transport leading to severe defects in sorting, secretion, and O-glycosylation |
| 基准测试用于抗体设计的生成模型 & 探索序列排名的对数似然性 |
Ucar, T. |
PDF |
N/A |
Benchmarking Generative Models for Antibody Design & Exploring Log-Likelihood for Sequence Ranking |
| 斑马鱼中rbfox1功能丧失导致bdnf/trkb2和pac1a表达失调，进而引起HPI轴过度激活、压力反应改变以及稳态过载。 |
Leggieri, A. |
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N/A |
rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload |
| 皮层阿尔法节律从自然场景背景中插值遮挡的运动 |
Yeh, L.-C. |
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N/A |
Cortical alpha rhythms interpolate occluded motion from natural scene context |
| 利用迁移学习预测蛋白质-小分子相互作用 |
Wang, J. |
PDF |
N/A |
Leveraging Transfer Learning for Predicting Protein-Small Molecule Interactions |
| 复杂多途径反应动力学分析：胰岛素二聚体解离 |
Jeong, K. |
PDF |
N/A |
Analysis of the dynamics of a complex, multipathway reaction: Insulin dimer dissociation |
| 预融合AAA+重塑目标-SNARE蛋白复合物促进突触传递 |
White, K. I. |
PDF |
N/A |
Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission |
| 不可或缺却又可有可无：肉桂酸4-羟化酶在水稻细胞壁木质化中的作用 |
Supatmi, S. |
PDF |
N/A |
Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification |
| 两种亚麻品种的比较分析表明木脂素介导的盐胁迫适应性 |
Debnath, A. J. |
PDF |
N/A |
A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness |
| 过去100年育种过程中小麦根系水力特性的演变 |
Baca Cabrera, J. C. |
PDF |
N/A |
The evolution of root hydraulic traits in wheat over 100 years of breeding |
| PhenoVision：一个用于从现场图像自动化生成并交付研究就绪植物物候数据的框架 |
Dinnage, R. |
PDF |
N/A |
PhenoVision: A framework for automating and delivering research-ready plant phenology data from field images |
| 在致死温度限制以下的升高发育温度会降低埃及伊蚊的繁殖力。 |
Peklanska, M. |
PDF |
N/A |
Elevated developmental temperatures below the lethal limit reduce Aedes aegypti fertility |
| 气候和睡眠模式中的纬度梯度影响感染了绿僵菌的果蝇黑腹果蝇的疾病结果 |
Nan, M. |
PDF |
N/A |
Latitudinal clines in climate and sleep patterns shape disease outcomes in Drosophila melanogaster infected by Metarhizium anisopliae |
| FiNNpy 2.0：快速MEG源重建 |
Crompton, D. |
PDF |
N/A |
FiNNpy 2.0: Fast MEG source reconstruction |
| 使用时间干扰正弦刺激选择性阻断C纤维传导以抑制内脏痛觉 |
Zhang, S. |
PDF |
N/A |
Suppression of Visceral Nociception by Selective C-Fiber Transmission Block Using Temporal Interference Sinusoidal Stimulation |
| 膜与皮质附着蛋白的笼蔽作用可引发细胞对称性的破坏。 |
Dar, S. |
PDF |
N/A |
Caging of membrane-to-cortex attachment proteins can trigger cellular symmetry breaking |
| 研究全氟己烷磺酸（PFHxS）对感觉运动和昼夜节律发育的影响 |
Ferdous, S. R. |
PDF |
N/A |
Examining perfluorohexane sulfonate (PFHxS) impacts on sensorimotor and circadian rhythm development |
| FieldDino：用于植物育种研究的高通量生理形态表型分析的气孔特征 |
Chaplin, E. D. |
PDF |
N/A |
FieldDino: High-throughput physio-morphological phenotyping of stomatal characteristics for plant breeding research |
| 晚更新世气候对林地草莓基因组的影响：一种多年生草本植物的故事 |
Toivainen, T. |
PDF |
N/A |
Late Quaternary climatic impact on the woodland strawberry genome: a perennial herb's tale |
| 在芸苔属芥菜的同源多倍体中敲除脂肪酸延伸酶1同源等位基因会导致种子油中无法检测到芥酸。 |
Patra, N. |
PDF |
N/A |
Knockout of fatty acid elongase1 homeoalleles in amphidiploid Brassica juncea leads to undetectable erucic acid in seed oil |
| 非侵入性、基于生物发光的时间动态可视化和量化拟南芥中的细菌感染 |
Taks, N. W. |
PDF |
N/A |
Non-invasive, bioluminescence-based visualization and quantification of bacterial infections in Arabidopsis over time |
| 特定细菌分类群及其代谢物DHPS与阿尔茨海默病、帕金森病和肌萎缩侧索硬化症的关联。 |
Ellis, J. C. |
PDF |
N/A |
Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis. |
| 特定细菌分类群及其代谢物DHPS与阿尔茨海默病、帕金森病和肌萎缩侧索硬化症的关联。 |
Christopher, C. J. |
PDF |
N/A |
Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis. |
| 脂肪酸延长酶eloF的调控变化是果蝇prolongata中性别特异性信息素谱系进化的基础 |
Yige, L. |
PDF |
N/A |
Regulatory Changes in the Fatty Acid Elongase eloF Underlie the Evolution of Sex-specific Pheromone Profiles in Drosophila prolongata |
| 深度相机捕捉到的产蛋母鸡在拍翅时的最大垂直高度 |
Grebey, T. |
PDF |
N/A |
Maximum vertical height during wing flapping of laying hens captured with a depth camera |
| 芬太尼强化史对多步骤决策的影响具有性别特异性 |
Garr, E. |
PDF |
N/A |
Fentanyl reinforcement history has sex-specific effects on multi-step decision-making |
| 用于即时伤口诊断的pH感应伤口敷料比色检测方法 |
Cherifi, K. |
PDF |
N/A |
Colorimetric detection methods of pH-sensing wound dressing for point-of-care wound diagnostics |
| 探索蛋白质-DNA结合残基预测及利用深度学习进行一致性可解释性分析 |
Liu, Y. |
PDF |
N/A |
Exploring Protein-DNA Binding Residue Prediction and Consistent Interpretability Analysis Using Deep Learning |
| 具有tau病理特征的特发性震颤在形态上与阿尔茨海默病和原发性年龄相关tau病变的种子无法区分。 |
Saez-Calveras, N. |
PDF |
N/A |
Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy |
| 具有tau病理特征的特发性震颤在形态上与阿尔茨海默病和原发性年龄相关tau病变的种子无法区分。 |
Saez-Calveras, N. |
PDF |
N/A |
Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy |
| 双特异性磷酸酶1（DUSP1）作为子痫前期的非侵入性循环生物标志物候选者 |
Andrieu, J. |
PDF |
N/A |
Dual specificity phosphate 1 (DUSP1) as a non-invasive circulating biomarker candidate in preeclampsia |
| PERM1是否调节心脏收缩功能？一场数字游戏。 |
Zaitsev, A. V. |
PDF |
N/A |
Does PERM1 Regulate Systolic Cardiac Function? A Game of Numbers. |
| 列当（Orobanche cumana Wallr）控制：向日葵杂交种的可持续性研究及寄生虫防护策略 |
Khablak, S. |
PDF |
N/A |
CONTROL OF OROBANCHE CUMANA WALLR: RESEARCH ON SUSTAINABILITY OF SUNFLOWER HYBRIDS AND STRATEGIES FOR PARASITE PROTECTION |
| 人类大脑在首次使用迷幻蘑菇碱后发生变化 |
Lyons, T. |
PDF |
N/A |
Human brain changes after first psilocybin use |
| IGF-1 影响癫痫性痉挛生成与缓解中的新皮质中间神经元连接性 |
Ballester-Rosado, C. J. |
PDF |
N/A |
IGF-1 IMPACTS NEOCORTICAL INTERNEURON CONNECTIVITY IN EPILEPTIC SPASM GENERATION AND RESOLUTION |
| 轴突特异性微管调控驱动感觉神经元轴突的不对称再生 |
Costa, A. C. |
PDF |
N/A |
Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons |
| TGF-β1/mTORC1信号轴在定义CTHRC1+病理性成纤维细胞的转录特征中起关键作用 |
Wilson, J.-A. A. M. |
PDF |
N/A |
Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts |
| 通过加权基因相关网络和生物信息学分析鉴定糖尿病相关创伤性脑损伤的关键基因和富集生物过程 |
Saidu, U. F. |
PDF |
N/A |
Identification of key genes and enriched biological processes in diabetes-associated traumatic brain injury through weighted gene correlation network and bioinformatics analysis |
| 果蝇翅膀平面极化过程中细胞尺度信号传递的强有力证据 |
Carayon, A. |
PDF |
N/A |
Evidence for strong cell-scale signalling during planar polarisation in the Drosophila wing |
| 敲除蛋白质组学揭示USP7通过AJUBA调节结直肠癌中的细胞间粘附 |
Al-Eidan, A. |
PDF |
N/A |
Knockdown proteomics reveals USP7 as a regulator of cell-cell adhesion in colorectal cancer via AJUBA |
| 利用CRISPR条形码作为分子钟，以单细胞分辨率捕捉动态过程 |
Andres-Lopez, Y. |
PDF |
N/A |
Using CRISPR barcoding as a molecular clock to capture dynamic processes at single-cell resolution |
| 人类成肌纤维FHOD3介导的肌动蛋白延伸对于心肌细胞肌节完整性是必需的。 |
Valencia, D. A. |
PDF |
N/A |
Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes |
| 使用光学镊子对细胞力学进行稳健定量 |
Rodenburg, W. S. |
PDF |
N/A |
Robust quantification of cellular mechanics using optical tweezers |
| 胆固醇通过共同的非经典结合位点差异性地调节阿片和毒蕈碱受体的活性 |
Chetverikov, N. |
PDF |
N/A |
Cholesterol differentially modulates the activity of opioid and muscarinic receptors via common non-canonical binding site |
| 结核空洞中贝达喹啉扩散的动力学为耐药性的出现提供了契机。 |
Bustion, A. E. |
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N/A |
The kinetics of bedaquiline diffusion in tuberculous cavities opens a window for emergence of resistance. |
| 回到未来：利用多基因本地适应的环境基因组选择 |
Halpin-McCormick, A. |
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N/A |
Back to the Future: Environmental genomic selection to take advantage of polygenic local adaptation |
| 油菜黄单胞菌（Xanthomonas campestris pv. campestris）的四种细胞壁降解酶决定了细菌从排水孔逃逸到叶片脉管系统的过程。 |
Paauw, M. |
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N/A |
Four cell wall-degrading enzymes of Xanthomonas campestris pv. campestris determine bacterial escape from hydathodes to the leaf vasculature |
| 葡萄糖依赖的糖鞘脂生物合成促进CD8+ T细胞功能和肿瘤控制 |
Longo, J. |
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N/A |
Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control |
| 非协变存储效应：对放大随机适应性和人口统计波动的突变等位基因的正向选择 |
Kim, Y. |
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N/A |
Noncovarying storage effect: positive selection on mutant alleles that amplify random fitness and demographic fluctuations |
| 在检测欧洲白蜡树（Fraxinus excelsior）对白蜡枯梢病耐受性方面，临时基因分型方法的局限性 |
Szukala, A. |
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N/A |
Limitations of ad hoc genotyping in detecting ash dieback tolerance in Fraxinus excelsior |
| 人类小动脉染色质相互作用图谱揭示了血压遗传调控的新机制 |
Liu, Y. |
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N/A |
Chromatin interaction maps of human arterioles reveal new mechanisms for the genetic regulation of blood pressure |
| CandyCollect：一种用于直接捕获和计数唾液外泌体的开放式微流控装置 |
Pierce, C. |
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N/A |
CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles |
| CandyCollect：一种用于直接捕获和计数唾液外泌体的开放式微流控设备 |
Pierce, C. A. |
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N/A |
CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles |
| 半监督组学因子分析（SOFA）能够从多组学数据中分离出已知的变异源和潜在因子。 |
Capraz, T. |
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N/A |
Semi-supervised Omics Factor Analysis (SOFA) disentangles known sources of variation from latent factors in multi-omics data |
| prolfquapp - 一个用户友好的命令行工具，简化定量蛋白质组学中的差异表达分析 |
Wolski, W. E. |
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N/A |
prolfquapp - A User-Friendly Command-Line Tool Simplifying Differential Expression Analysis in Quantitative Proteomics |
| 双途径共表达分析框架（D-CAF）能够从多组学时间序列数据中识别出新的昼夜节律调控 |
Chuah, J. R. |
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N/A |
Dual-Approach Co-expression Analysis Framework (D-CAF) Enables Identification of Novel Circadian Regulation From Multi-OmicTimeseries Data |
| 肝细胞癌中关键基因的鉴定及CDK1靶向治疗药物：生物信息学与模拟研究 |
Romero, R. |
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N/A |
Identification of Hub Genes and CDK1-Targeting Therapeutics in Hepatocellular Carcinoma: Bioinformatics and Simulation Study |
| 解读肠道微生物群对抑郁症的影响：基于社区水平的约束代谢建模方法 |
Yuchen, Z. |
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N/A |
Deciphering the Gut Microbiome's Influence on Depression: A Community-Level Constraint-Based Metabolic modelling Approach |
| 基于基因扰动从scATAC-seq数据推断基因调控网络 |
Shao, W. |
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N/A |
Inferring Gene Regulatory Network Based on scATAC-seq Data with Gene Perturbation |
| 雌激素受体1在肝星状细胞中的信号传导决定了对肝纤维化的抵抗性 |
Li, T. |
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N/A |
Estrogen Receptor 1 Signaling in Hepatic Stellate Cells Designates Resistance to Liver Fibrosis |
| AZ12464237作为P2Y12受体的高亲和力非核苷酸拮抗剂放射性配体的表征 |
Steen, J. |
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N/A |
Characterization of AZ12464237 as a high affinity, non-nucleotide antagonist radioligand for the P2Y12 receptor |
| 利用斑马鱼快速筛选方法鉴定潜在的败血症治疗药物 |
Widder, M. W. |
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N/A |
Identification of potential sepsis therapeutic drugs using a zebrafish rapid screening approach |
| 缺乏证据表明锥状光感受器对人类夜间褪黑素抑制和警觉反应的贡献 |
Fazlali, F. |
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N/A |
Lack of evidence for the contribution of cone photoreceptors to human melatonin suppression and alerting response to light at night |
| 作为有毒环境毒物在突触核蛋白病模型中的作用 |
Shvachiy, L. |
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N/A |
Lead as a toxic environmental toxicant in models of synucleinopathies |
| 高原暴露对海平面居民骨骼肌线粒体亚细胞分布、超微结构及呼吸功能的影响 |
Schytz, C. T. |
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N/A |
Effect of high-altitude exposure on skeletal muscle mitochondrial subcellular distribution, ultrastructure and respiration in sea-level residents |
| 在发育过程中，拟南芥细胞壁的纤维网络特性被用来调节其机械性能。 |
Chen, S. |
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N/A |
Mechanical properties are tuned during development with the fibrous network nature of the Arabidopsis cell wall |
| MMM与CLCFM：基于摄影测量的三维点云重建方法，针对单株植物旋转拍摄的全方位图像 |
Hayashi, A. |
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N/A |
MMM and CLCFM: A 3D point cloud reconstruction method based on photogrammetry for all-around images taken by rotating an individual plant |
| 使用不同LED光配方塑造羽衣甘蓝的形态和生理 |
Scandola, S. |
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N/A |
Shaping Kale Morphology and Physiology Using Different LED Light Recipes |
| ERECTA家族信号在拟南芥胚珠起始过程中控制细胞命运的特化。 |
Overholt, A. M. |
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N/A |
ERECTA family signaling controls cell fate specification during ovule initiation in Arabidopsis. |
| 不同环境胁迫下高粱（Sorghum bicolor）蜡质层动态变化揭示了与蜡质生成相关的信号模块 |
Larson, M. |
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N/A |
Wax bloom dynamics on Sorghum bicolor under different environmental stresses reveal signaling modules associated with wax production |
| 孢粉素生物合成中的聚酮途径是陆地植物（胚胎植物）所特有的。 |
Suh, D.-Y. |
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N/A |
The polyketide pathway in sporopollenin biosynthesis is specific to land plants (Embryophyta) |
| SOX10与微小RNA：解析它们在调控黑色素瘤可塑性中的相互作用 |
Lai, X. |
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N/A |
SOX10 and microRNAs: decoding their interplay in regulating melanoma plasticity |
| AxSpA关节组织的特点是存在HLA-DR+组织驻留记忆（TRM）和杀伤细胞免疫球蛋白样受体（KIR）+ CD8+ T细胞亚群。 |
Liu, F. |
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N/A |
AxSpA joint tissue is characterised by HLA-DR+ tissue resident memory (TRM) and killer cell immunoglobulin-like receptor (KIR)+ CD8+ T cell subsets |
| 几丁寡糖对多微生物脓毒症的保护作用通过N-乙酰-D-葡萄糖胺残基进行了精细调节。 |
Patel, P. |
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N/A |
Protection against Poly Microbial Sepsis by Chitin oligomersis fine tuned by N-Acetyl D-Glucosamine residues |
| 多模态分析揭示CD4+CXCR5+PD-1- Tfh细胞作为人类弥漫性大B细胞淋巴瘤（DLBCL）中R-CHOP疗法反应的预后和预测生物标志物 |
Yu, S. |
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N/A |
Multi-modal profiling identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers for response to R-CHOP therapy in human DLBCL |
| 对果蝇中年龄和性别特异性线粒体-核互作的检测 |
Garlovsky, M. D. |
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N/A |
Testing for age- and sex- specific mitonuclear epistasis in Drosophila |
| 解码基因表达在不同细胞和疾病状态下的序列决定因素 |
Lal, A. |
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N/A |
Decoding sequence determinants of gene expression in diverse cellular and disease states |
| 儿童患者肺静脉狭窄的分子机制洞察 |
Kalustian, A. B. |
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N/A |
Insights into the Molecular Mechanism of Pulmonary Vein Stenosis in Pediatric Patients |
| 器官芯片设备的毒物代谢动力学 |
Hermann, N. G. |
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N/A |
Toxicokinetics for organ-on-chip devices |
| 使用加权非平行近端支持向量机的细菌菌株传播生物标志物的迁移学习模型 |
Ugwu, U. O. |
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N/A |
Transfer Learning Models for Bacterial Strain Dissemination Biomarkers using Weighted Non-Parallel Proximal Support Vector Machines |
| 微生物组知识图谱（MicrobiomeKG）：通过知识图谱连接微生物组研究与宿主健康 |
Goetz, S. |
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N/A |
MicrobiomeKG: Bridging Microbiome Research and Host Health Through Knowledge Graphs |
| 行动中的公平：四年迈向生物化学招聘中性别平等和种族多样化的旅程 |
Christian, S. L. |
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N/A |
Equity in Action: A Four-Year journey towards Gender Parity and Racial Diversity in Biochemistry Hiring |
| 自由活动小鼠的高通量双光子体积脑成像 |
Qian, L. |
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N/A |
High-throughput two-photon volumetric brain imaging in freely moving mice |
| 抑制作用解决西蒙冲突：来自脑电图解码的证据 |
Lee, Y. S. |
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N/A |
Inhibition Resolves Simon Conflict: Evidence from EEG Decoding |
| 用于研究人体神经系统环路回路的Assembloid模型 |
Miura, Y. |
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N/A |
Assembloid model to study loop circuits of the human nervous system |
| 通过高阶协方差矩阵分解实现高效的上位效应推断 |
Shimagaki, K. S. |
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N/A |
Efficient epistasis inference via higher-order covariance matrix factorization |
| 人胰腺癌中磷酸化酪氨酸突变型结蛋白的鉴定 |
Kendrick, N. C. |
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N/A |
Identification of Phosphotyrosine-Mutant Desmin in Human Pancreatic Cancer |
| 细胞内钙感知复合物CPKs/ECA1调控细胞质钙稳态以控制植物的渗透敏感性 |
Liang, X. |
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N/A |
An intracellular calcium sensory complex CPKs/ECA1 controls cytosolic calcium homeostasis for plant osmosensitivity |
| 在节肢动物中诱导白内障揭示了晶状体蛋白如何促进生物玻璃的形成 |
Mitra, A. T. |
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N/A |
Cataract induction in an arthropod reveals how lens crystallins contribute to the formation of biological glass |
| 在缺乏细胞死亡的情况下，选择性脑干神经元中的Tau负荷预测平衡缺陷的严重程度和性质。 |
Zhu, Y. |
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N/A |
Tau load in select brainstem neurons predicts the severity and nature of balance deficits in the absence of cell death |
| 丙酮酸脱氢酶激酶1调控心肌细胞中甘油三酯的水解 |
Atser, M. G. |
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N/A |
Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes |
| 未经治疗的非小细胞肺癌（NSCLC）光学成像揭示了与转移复发相关的变化 |
Diaz, P. M. |
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N/A |
Optical imaging of treatment-naive human NSCLC reveals changes associated with metastatic recurrence |
| 己糖胺生物合成途径通过改变细胞骨架来调节转移性前列腺癌中的细胞增殖和迁移。 |
Shakya, R. |
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N/A |
The Hexosamine Biosynthetic Pathway alters the cytoskeleton to modulate cell proliferation and migration in metastatic prostate cancer |
| 神经炎症与自发性高血压易中风大鼠的高血压相关脊髓病理学 |
Noyan, H. |
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N/A |
Neuroinflammation and Spinal Cord Pathology Associated with Hypertension in Spontaneously Hypertensive Stroke-Prone Rats |
| 鉴定和靶向气道上皮中调节SARS-CoV-2-宿主相互作用的因子。 |
Dirvin, B. G. |
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N/A |
Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium. |
| 卡莫氟类似物作为抗增殖剂、SARS-CoV-2主蛋白酶（Mpro）抑制剂和膜破裂诱导剂的合成与评估 |
Gu, T. |
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N/A |
Synthesis and Evaluation of Carmofur Analogs as Antiproliferative Agents, Inhibitors to the Main Protease (Mpro) of SARS-CoV-2, and Membrane Rupture-Inducing Agents |
| 基于八个协变量对COVID-19患者疾病严重程度进行预测的机器学习算法比较评估 |
Patel, T. S. |
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N/A |
Comparative assessment of machine learning algorithms to predict severity of disease in COVID-19 patients based on eight cofactors |
| 全球转录因子分析揭示了铜绿假单胞菌中调控网络的层次结构、协同作用及主要毒力调控因子 |
Huang, J. |
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N/A |
Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa |
| 改进氨基酸生物合成途径的注释：GapMind 2024 |
Price, M. N. |
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N/A |
Improving the annotation of amino acid biosynthesis pathways: GapMind 2024 |
| 膜结合型鸟苷酸环化酶COP5/HKR1改变纤毛搏动模式并影响衣藻在趋化过程中的细胞转向 |
Strain, A. L. |
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N/A |
Membrane-bound Guanylyl Cyclase COP5/HKR1 changes ciliary beat pattern and biases cell steering during chemotaxis in Chlamydomonas reinhardtii |
| 农场暴露与人类母乳免疫特征和微生物群相关 |
Swaney, M. H. |
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N/A |
Farm exposure is associated with human breast milk immune profile and microbiome |
| Cas9和雷帕霉素诱导的Cre重组酶的组成型表达促进了伯氏疟原虫中的条件性基因组编辑 |
Das, S. |
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N/A |
Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei |
| 从辣木中合成银纳米颗粒：预防SARS-CoV-2污染水的潜力 |
Shittu, M. O. |
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N/A |
Green synthesized silver nanoparticles from Moringa: Potential for preventative treatment of SARS-CoV-2 contaminated water |
| 核糖体蛋白bS1在正交mRNA起始密码子选择中的作用 |
Boyko, K. V. |
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N/A |
Role of ribosomal protein bS1 in orthogonal mRNA start codon selection |
| 氧化性RNA损伤对SARS-CoV-2依赖RNA的RNA聚合酶体外复制的影响 |
Akagawa, M. |
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N/A |
Impact of an Oxidative RNA Lesion on in vitro Replication Catalyzed by SARS-CoV-2 RNA-dependent RNA Polymerase |
| 大肠杆菌中的集体β-内酰胺耐药性：细胞死亡时释放β-内酰胺酶所致 |
Gross, R. |
PDF |
N/A |
Collective β-lactam resistance in Escherichia coli due to β-lactamase release upon cell death |
| 免疫细胞促进感染肠道病毒D68的小鼠出现瘫痪性疾病 |
Woods Acevedo, M. A. |
PDF |
N/A |
Immune cells promote paralytic disease in mice infected with enterovirus D68 |
| 杀手酵母在种植真菌蚂蚁花园中的普遍存在及新型杀手毒素Ksino的发现 |
Bizarria, R. |
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N/A |
The Prevalence of Killer Yeasts in the Gardens of Fungus-Growing Ants and the Discovery of Novel Killer Toxin named Ksino. |
| 全基因组分析发现粪肠球菌中促进与卷曲乳杆菌种间竞争的基因 |
Lam, L. N. |
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N/A |
Genome-wide analysis of Enterococcus faecalis genes that facilitate interspecies competition with Lactobacillus crispatus |
| 通过mRNA展示技术支持的机器学习模型评估环脱水酶LynD的底物范围 |
Steude, E. G. |
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N/A |
Assessing substrate scope of the cyclodehydratase LynD by mRNA display-enabled machine learning models |
| 线粒体DNA突变连接Leigh综合征和颈动脉动脉粥样硬化：一项关于共享遗传途径的研究 |
Sharma, A. |
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N/A |
Mitochondrial DNA Mutations Linking Leigh Syndrome and Carotid Atherosclerosis: A Study of Shared Genetic Pathways |
| 多形拟杆菌（Bacteroides thetaiotaomicron）增强了沃氏嗜胆菌（Bilophila wadsworthia）中硫化氢的产生。 |
Davies, J. |
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N/A |
Bacteroides thetaiotaomicron enhances H2S production in Bilophila wadsworthia |
| 实时高分辨率显微镜揭示了单细胞裂解如何塑造生物膜基质形态发生 |
Squyres, G. R. |
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N/A |
Real-time high-resolution microscopy reveals how single-cell lysis shapes biofilm matrix morphogenesis |
| 香草木犀素抑制登革病毒NS5甲基转移酶的机制性见解 |
Bhutkar, M. |
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N/A |
Mechanistic insights into the inhibition of dengue virus NS5 methyltransferase by herbacetin |
| 芜菁黄花叶病毒颗粒的结构。读取通域是如何暴露在衣壳表面的？ |
Lai-Kee-Him, J. |
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N/A |
Structure of the turnip yellows virus particles. How is the readthrough domain exposed on the capsid surface? |
| 真菌病原体球孢子菌形态发育的转录组图谱揭示了关键阶段富集的转录本 |
Homer, C. M. |
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N/A |
Transcriptomic atlas of the morphologic development of the fungal pathogen Coccidioides reveals key phase-enriched transcripts |
| 细菌鉴定和感染性疾病诊断中的16S rRNA基因测序 |
Li, M.-N. |
PDF |
N/A |
16S rRNA gene sequencing for bacterial identification and infectious disease diagnosis |
| 铜绿假单胞菌金属应答TonB依赖转运蛋白的特性分析 |
Ferry, M. |
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N/A |
Characterisation of Pseudomonas aeruginosas metal-responsive TonB-dependent transporters |
| 致病性相关黏附素通过生物膜形成驱动共生菌在蜜蜂肠道中的定殖 |
Lariviere, P. J. |
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N/A |
Virulence-linked adhesin drives mutualist colonization of the bee gut via biofilm formation |
| 肝脏CYP4A自噬-溶酶体降解（ALD）：自噬受体SQSTM1/p62通过一个不常见的靶点相互作用位点发挥主要作用 |
He, L. |
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N/A |
Liver CYP4A autophagic-lysosomal degradation (ALD): A major role for the autophagic receptor SQSTM1/p62 through an uncommon target interaction site |