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BioRxiv 2024-10-16 Papers

标题 作者 PDF链接 代码仓库 Title
长期胞外记录中神经活动追踪的通用框架 Chaure, F. J. PDF N/A General Framework for Tracking Neural Activity Over Long-Term Extracellular Recordings
池塘蜻蜓生态位的持久性,奠定了尽管选择变异,适应区依然稳定的基础。 Gupta, A. PDF N/A Persistence of the ecological niche in pond damselflies underlies a stable adaptive zone despite varying selection
鼻内自我扩增RNA SARS-CoV-2疫苗产生保护性呼吸和系统性免疫,并防止病毒传播。 Jennewein, M. F. PDF N/A Intranasal self-amplifying RNA SARS-CoV-2 vaccine produces protective respiratory and systemic immunity and prevents viral transmission
利用PlatinumCRISPr进行结构优化的sgRNA选择,以高效生成Cas9敲除 Haussmann, I. U. PDF N/A Structure-optimized sgRNA selection with PlatinumCRISPr for efficient Cas9 generation of knock-outs
全基因组测序数据中剪接改变变异的函数聚类揭示了罕见变异疾病的隐藏遗传性 Wang, Y. PDF N/A Functional clustering of splice-altering variants in whole genome sequencing data reveals hidden heritability in rare variant disorder
视觉空间动力学驱动沉浸式环境中的适应性社会学习 Wu, C. M. PDF N/A Visual-spatial dynamics drive adaptive social learning in immersive environments
saseR:平衡偏移量解锁了RNA测序工具,实现快速、可扩展的差异使用、异常剪接和表达检索。 Segers, A. PDF N/A saseR: Juggling offsets unlocks RNA-seq tools for fast and Scalable differential usage, Aberrant Splicing and Expression Retrieval.
鉴定允许鲍氏不动杆菌维持高水平氟喹诺酮类耐药性的决定因素 Hamami, E. PDF N/A Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii
预测基于CRISPR-Cas9的表观基因组编辑效果 Batra, S. S. PDF N/A Predicting the effect of CRISPR-Cas9-based epigenome editing
通过免疫球蛋白A抑制上皮细胞增殖和肿瘤发生 Donaldson, G. P. PDF N/A Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A
小鼠眶额皮层中信息内在价值的表征 Bussell, J. J. PDF N/A Representations of the intrinsic value of information in mouse orbitofrontal cortex
高效编码解释了神经响应稳态和刺激特异性适应 Young, E. J. PDF N/A Efficient coding explains neural response homeostasis and stimulus-specific adaptation
食物竞争影响繁殖干扰的强度及其对物种共存的后果。 Cruz, M. A. PDF N/A Competition for food affects the strength of reproductive interference and its consequences for species coexistence.
热带马利筋(Asclepias curassavica)的基因组和组织特异性转录组 Feng, H. PDF N/A Genome and tissue-specific transcriptome of the tropical milkweed (Asclepias curassavica)
靶向星形胶质细胞可减轻脊髓损伤后的神经病理性疼痛 Zhao, Q. PDF N/A Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury
在酵母极性网络的补偿性进化过程中,全球基因重塑 Kingma, E. PDF N/A Global genetic rewiring during compensatory evolution in the yeast polarity network
tRNA低修饰通过激活交叉途径控制系统促进烟曲霉对5-氟胞嘧啶的抗性。 Bruch, A. PDF N/A tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.
在变量选择前的排列分析大大增强了OPLS分析在小样本群体中的鲁棒性。 Ström, M. PDF N/A The permutation analysis prior to variable selection greatly enhances robustness of OPLS analysis in small cohorts
PRC2.1亚复合物通过调节CCND1和CCND2来抑制G1期进展 Longhurst, A. D. PDF N/A The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2
遗传多样性对跨越营养级的生态系统功能的影响与物种多样性一样大,但方向相反。 Fargeot, L. PDF N/A Genetic diversity affects ecosystem functions across trophic levels as much as species diversity, but in an opposite direction
自上而下起源的捕食者-猎物幂律的一般机制 Mazzarisi, O. PDF N/A General mechanisms for a top-down origin of the predator-prey power law
AgeML:利用机器学习进行年龄建模 Garcia Condado, J. PDF N/A AgeML: Age modelling with Machine Learning
沃尔巴克氏菌增强了交配前和交配后早期隔离在螨虫中的匹配度 Cruz, M. A. PDF N/A Wolbachia strengthens the match between pre-mating and early post-mating isolation in spider mites
BIMSA:利用内存处理加速长序列比对 Alonso-Marin, A. PDF N/A BIMSA: Accelerating Long Sequence Alignment Using Processing-In-Memory
大规模基因组重排的爆发式发生与非海洋环节动物的起源 Vargas-Chavez, C. PDF N/A A punctuated burst of massive genomic rearrangements and the origin of non-marine annelids
谷氨酸/GABA共传递的独特释放特性起到了对上丘脑输入的频率依赖性过滤作用。 Hirai, H. PDF N/A Distinct release properties of glutamate/GABA co-transmission serve as a frequency-dependent filtering of supramammillary inputs
diaTracer能够对基于diaPASEF的蛋白质组学数据进行以光谱为中心的分析。 Li, K. PDF N/A diaTracer enables spectrum-centric analysis of diaPASEF proteomics data
规模至关重要:拥有数十亿(而非数百万)参数的大型语言模型更能与自然语言的神经表征相匹配。 Hong, Z. PDF N/A Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language
提取后去甲肾上腺素激活会损害后续记忆,这取决于皮层-海马再激活的作用。 Heinbockel, H. PDF N/A Post-retrieval noradrenergic activation impairs subsequent memory depending on cortico-hippocampal reactivation
第三种情景记忆:情景熟悉度与项目熟悉度和回忆是不同的 Addante, R. J. PDF N/A A third kind of episodic memory: Context familiarity is distinct from item familiarity and recollection
北亚得里亚海(地中海)中入侵物种波氏多毛虫(多毛纲:缨鳃虫科)的大量存在 Lezzi, M. PDF N/A Massive presence of the invasive Polydora websteri (Polychaeta: Spionidae) in the North Adriatic Sea (Mediterranean Sea)
在正常听力中年成人中,增加的听力努力和耳蜗神经退化是导致噪音环境下言语感知行为缺陷的基础。 Zink, M. E. PDF N/A Increased listening effort and cochlear neural degeneration underlie behavioral deficits in speech perception in noise in normal hearing middle-aged adults.
大型蛋白质数据库揭示了结构互补性和功能局部性 Szczerbiak, P. PDF N/A Large protein databases reveal structural complementarity and functional locality
用于可视化多胺水平、摄取和分布的基因编码荧光传感器 Tamura, R. PDF N/A Genetically encoded fluorescent sensors for visualizing polyamine levels, uptake, and distribution
使用Glittr.org查找、比较并重复利用在线培训和教育材料 van Geest, G. PDF N/A Using Glittr.org to find, compare and re-use online materials for training and education
旁分泌拯救MYR1缺陷型刚地弓形虫突变体揭示了体内CRISPR筛选的局限性 Torelli, F. PDF N/A Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens
ERGtools2 包:用于处理和分析视觉电生理数据的工具集 Lindner, M. PDF N/A The ERGtools2 package: A Toolset for Processing and Analysing Visual Electrophysiology Data
物体非刚性各向异性:皮层各向异性的高级知觉后果 Maruya, A. PDF N/A Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy
果蝇piRNA通路中蛋白质相互作用的反复创新 Riedelbauch, S. PDF N/A Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway
数据驱动的改进抗体选择适宜免疫原评估 Waury, K. PDF N/A Data-driven evaluation of suitable immunogens for improved antibody selection
区域特异性扩散去极化驱动异常的癫痫后行为 Mitlasoczki, B. PDF N/A Region-specific spreading depolarization drives aberrant post-ictal behavior
生物学中的弱磁场效应是可以测量的——在不存在地磁场的情况下,非洲爪蟾胚胎发育加速。 Lodesani, A. PDF N/A Weak magnetic field effects in biology are measurable--accelerated Xenopus embryogenesis in the absence of the geomagnetic field
利用新型基因组资源和统计方法结合个体和群体测序数据,深入探讨过去和未来斑翅果蝇(Drosophila suzukii)的入侵情况 Camus, L. PDF N/A New insights into past and future invasion of Drosophila suzukii using novel genomic resources and statistical methods to combine individual and pool sequencing data
自催化循环的热力学一致性 Kosc, T. PDF N/A Thermodynamic consistency of autocatalytic cycles
印度荠菜(Rorippa indica)的种内基因组大小变异揭示了通过基因组扩增实现的热带适应性 Han, T.-S. PDF N/A Intraspecific genome size variation in Rorippa indica reveals a tropical adaptation by genomic enlargement
大鼠从空间距离到社交距离的信息传递:对后顶叶皮层在空间-社交整合中作用的影响 Wise, T. B. PDF N/A Information transfer from spatial to social distance in rats: implications for the role of the posterior parietal cortex in spatial-social integration
隔离节拍显著性对节奏听觉刺激效果的影响 Von Handorf, K. M. PDF N/A Isolating the effect of beat salience on rhythmic auditory stimulation outcomes
人类腹侧颞叶皮层功能侧化的个体差异:局部竞争与长程耦合 Blauch, N. M. PDF N/A Individual variation in the functional lateralization of human ventral temporal cortex: Local competition and long-range coupling
从动作到言语:内侧额叶皮层沿着尾侧到吻侧的预测误差梯度进行动作监控 Dorokhova, L. PDF N/A From movements to words: action monitoring in the medial frontal cortex along a caudal to rostral prediction error gradient
注意力网络在不确定情况下与策略精确性相关的默认模式网络中发挥作用。 Yoon, D. PDF N/A Attention networks engage the default mode network related to policy precision under uncertainty
ZMYND11 在双模态调控潜伏基因和类脑剪接中发挥作用,以保障皮层发生 Chang, X. PDF N/A ZMYND11 Functions in Bimodal Regulation of Latent Genes and Brain-like Splicing to Safeguard Corticogenesis
脆性X综合征大鼠模型中受损的海马-前额叶网络:一项将神经动力学与自闭症样行为障碍联系起来的研究 Ouardouz, M. PDF N/A Disrupted Hippocampal-Prefrontal Networks In A Rat Model Of Fragile X Syndrome: A Study Linking Neural Dynamics To Autism-Like Behavioral Impairments
细胞外控制对新皮质神经元命运和多样性的影响 Baumann, N. PDF N/A Cell-extrinsic controls over neocortical neuron fate and diversity
快速且稳健的幼儿视觉物体识别 Ayzenberg, V. PDF N/A Fast and robust visual object recognition in young children
海马齿状回颗粒细胞亚型的多样化受Neuregulin1核反馈信号的调控。 Rajebhosale, P. PDF N/A Diversification of Dentate Gyrus Granule Cell Subtypes is Regulated by Neuregulin1 Nuclear Back Signaling.
增强小鼠发声的皮层-运动神经元投射 Boyd, J. L. PDF N/A Enhancing cortico-motoneuronal projections for vocalization in mice
光学分析突触和突触外位点的NMDA受体分子多样性 Sicard, A. PDF N/A Optical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites
一个自上而下的岛叶皮层回路,对非伤害性恐惧学习至关重要 Han, J. PDF N/A A top-down insular cortex circuit crucial for non-nociceptive fear learning
CB1大麻素受体和囊泡谷氨酸转运体-3表达神经末梢在大脑皮层中与GABA能神经元相关的突触靶点和细胞来源 Somogyi, P. PDF N/A Synaptic targets and cellular sources of CB1 cannabinoid receptor and vesicular glutamate transporter-3 expressing nerve terminals in relation to GABAergic neurons in the human cerebral cortex
不同物种和多种生物因素下祖先脑干去甲肾上腺素能神经元的多样性 Kelberman, M. A. PDF N/A Diversity of ancestral brainstem noradrenergic neurons across species and multiple biological factors
欧亚松鸦(Garrulus glandarius)在食物储藏中的排除推理 Hawkins, I. PDF N/A Reasoning by exclusion in food-caching Eurasian jays (Garrulus glandarius)
老鼠在意什么?内外环境对雄性对雌性尖叫声的反应的影响 Brunner, L. R. PDF N/A What matters to a mouse? Effects of internal and external context on male vocal response to female squeaks
宽吻海豚的哨声变异及其社会声学互动 Mustun, F. PDF N/A Whistle variability and social acoustic interactions in bottlenose dolphins
规范性脑形态计量学模型在不同种族群体中的普适性 Ge, R. PDF N/A Generalizability of Normative Models of Brain Morphometry Across Distinct Ethnoracial Groups
奖励驱动的运动适应需要强大的基底神经节-皮质回路 Leblois, A. PDF N/A Reward-driven adaptation of movements requires strong recurrent basal ganglia-cortical loops
同步动力学是导致不规则新皮层放电的潜在机制。 Pattadkal, J. J. PDF N/A Synchrony dynamics underlie irregular neocortical spiking
P73+ Cajal-Retzius细胞和Reelin在皮质形态发生中的不同贡献 Elorriaga, V. PDF N/A Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical morphogenesis
阿尔茨海默病早期糖萼系统健康及其与睡眠、认知和脑脊液生物标志物的关系。 Ray, N. J. PDF N/A Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers.
早期阿尔茨海默病中的淋巴系统健康及其与睡眠、认知和脑脊液生物标志物的关系。 Ray, N. J. PDF N/A Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers.
一个编码发声表达和接收的皮层位点 Pomberger, T. PDF N/A A Cortical Site that Encodes Vocal Expression and Reception
克里斯托弗·哥伦布家族成员的首个全面法医遗传学研究:他的曾曾孙 Navarro Vera, I. PDF N/A THE FIRST COMPREHENSIVE FORENSIC GENETIC STUDY OF A MEMBER OF CHRISTOPHER COLUMBUS' FAMILY: HIS GREAT-GREAT-GRANDSON
填补免疫治疗预测的空白:AGAE评分作为免疫检查点抑制剂反应的泛癌生物标志物 Ye, B. PDF N/A Bridging the Gap in Immunotherapy Prediction: The AGAE Score as a Pan Cancer Biomarker for Immune Checkpoint Inhibitor Response
Galectin-4-KO小鼠中记忆缺陷、长期增强作用及海马突触可塑性 Brocca, M. E. PDF N/A Deficient Memory, Long-Term Potentiation and Hippocampal Synaptic Plasticity in Galectin-4-KO Mice.
阵发性慢波事件作为创伤后癫痫的诊断和预测生物标志物 Van Hameren, G. PDF N/A Paroxysmal Slow Wave Events as a diagnostic and predictive biomarker for post-traumatic epilepsy
快速发作性肌张力障碍-帕金森病中的网络机制 Moeller, M. PDF N/A Network mechanisms in rapid-onset dystonia-parkinsonism
跑步机步态训练促进不完全脊髓损伤后的皮质脊髓束可塑性 Eisdorfer, J. T. PDF N/A Treadmill step training promotes corticospinal tract plasticity after incomplete spinal cord injury
端粒长度与中老年参与者认知功能的关系:来自老龄研究中代表性不足社区的初步研究 McLester-Davis, L. W. Y. PDF N/A Telomere length and cognitive function among middle-aged and older participants from communities underrepresented in aging research: A preliminary study
在破伤风毒素诱发的癫痫大鼠模型中动态多日癫痫发作周期:节奏演变及其对预测的启示 Zarei Eskikand, P. PDF N/A Dynamic Multiday Seizure Cycles in a Tetanus Toxin Rat Model of Epilepsy: Evolving Rhythms and Implications for Prediction
隐含的运动既不引导目光跟随,也不引导意图归属。 Görner, M. PDF N/A Implied motion guides neither gaze following nor intention attribution
心磷脂通过阻止LPS与Caspase 4/11结合,抑制非经典炎症小体,从而减轻体内的内毒素血症 Pizzuto, M. PDF N/A Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in Vivo
对埃塞俄比亚索马里地区新出现的皮肤利什曼病疫源地中一种独特的利什曼原虫热带种群体进行基因组特征分析 Abera, A. PDF N/A Genomic characterization of a unique population of Leishmania tropica in a new emerging focus of cutaneous leishmaniasis in Somali region of Ethiopia
PAF1C在RNAPII转录延伸过程中,别构激活CDK12/13激酶。 Lopez Martinez, D. PDF N/A PAF1C allosterically activates CDK12/13 kinase during RNAPII transcript elongation
太阳辐射的漫射比和光谱特性的年变化:温带季风区域的云层效应 Siriwardana, A. N. PDF N/A Annual Variability in Diffuse Ratio and Spectral Characteristics of Solar Radiation: Cloud Effects in a Temperate Monsoon Region
植物性状数据来源的重要性:西北欧和潘诺尼亚生态区的共有物种在两个地区的性状值不同 Sonkoly, J. PDF N/A Origin of plant trait data matters: Shared species of Northwestern Europe and the Pannonian Ecoregion have different trait values in the two regions
一种可传播癌症对袋獾生命史特征的影响 Strickland, K. PDF N/A Effects of a transmissible cancer on life-history traits in Tasmanian devils
多样化的祖先揭示了真核生物起源时期复杂的共生相互作用 Bernabeu, M. PDF N/A Diverse ancestries reveal complex symbiotic interactions during eukaryogenesis
在密集环境中,大黄蜂会提高其学习飞行的海拔。 Sonntag, A. PDF N/A Bumblebees increase their learning flight altitude in dense environments
小鼠中的精细社会歧视:对阿尔茨海默病早期检测的启示 Faure, L. M. PDF N/A Fine Social Discrimination of Siblings in Mice: Implications for Early Detection of Alzheimer's Disease
野生环境中,更大的鱼群能做出更好、更快的集体决策 Pacher, K. PDF N/A Better and faster collective decisions by larger fish shoals in the wild
酒精诱导的DNA交联修复的机制性见解:范可尼贫血核酸酶Slx4-Xpf-Ercc1的作用 Havlikova, J. PDF N/A Mechanistic Insights into Alcohol-Induced DNA Crosslink Repair by the Fanconi Anemia Nuclease Slx4-Xpf-Ercc1
利用冷冻电子断层扫描技术绘制海马体内神经元组织结构的分子图谱 Glynn, C. PDF N/A Charting the molecular landscape of neuronal organisation within the hippocampus using cryo electron tomography
无压力生物打印保留功能的人类原代和iPSC衍生的胰岛 Poklar, M. PDF N/A Stress-free Bioprinting of Human Primary and iPSC-derived Islets with Retained Functionality
全面肿瘤治疗场系统用于胶质母细胞瘤治疗的开发与验证:从原型设计到临床前评估 Wang, X. PDF N/A Development and Validation of a Comprehensive Tumor Treating Fields System for Glioblastoma Therapy: From Prototype Design to Preclinical Evaluation
在HA(pY)STACK中搜索磺酸酪氨酸(sY) Tzvetkov, J. PDF N/A Searching for Sulfotyrosines (sY) in a HA(pY)STACK
一种基于语义引导元路径方法的药物-靶标相互作用预测统一框架 Li, H. PDF N/A A unified framework for drug-target interaction prediction by semantic-guided meta-path method
非线性奇异值分解波束形成用于气泡超声成像 Zhang, G. PDF N/A Nonlinear Singular Value Decomposition Beamforming for Ultrasound Imaging of Gas Vesicles
慢性肥胖并不改变Tp53R270H/+小鼠的癌症生存率。 Panzeri, I. PDF N/A Chronic obesity does not alter cancer survival in Tp53R270H/+ mice
PPARα-ERRα交叉对话缓解了与代谢功能障碍相关的脂肪肝疾病进展 Antwi, M. B. PDF N/A PPARalpha-ERRalpha crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression
预测无脊椎动物对化学物质的吸收和消除动力学:关于残差方差建模的技术说明 van Lingen, H. J. PDF N/A Predicting uptake and elimination kinetics of chemicals in invertebrates: a technicalnote on residual variance modeling
GCS-H2对于生长至关重要,因为它在拟南芥异养组织中作为线粒体脂酰化的主要中继器发挥作用。 Przybyla-Toscano, j. PDF N/A GCS-H2 is essential for growth as it acts as the main relay for mitochondrial lipoylation in heterotrophic tissues of Arabidopsis thaliana
基于数据和知识的溶质载体功能景观 Goldmann, U. PDF N/A Data- and knowledge-derived functional landscape of human solute carriers
降低与激活负担基因电路相关的切换成本,有助于提高细胞群体的均一性和生产力。 Henrion, L. PDF N/A Lowering the switching cost related to the activation of burdensome gene circuits promotes cell population homogeneity and productivity
系统级分析揭示了由甲基营养菌(Bacillus methanolicus)以甲醇为原料生产L-谷氨酸及其脱羧产物γ-氨基丁酸的机制。 Irla, M. PDF N/A Systems-level analysis provides insights on methanol-based production of L-glutamate and its decarboxylation product γ-aminobutyric acid by Bacillus methanolicus
生物抗性可预测地改变微生物入侵模式 Ye, X. PDF N/A Biotic resistance predictably shifts microbial invasion regimes
人类大脑广泛激活的睡眠节律 Wang, H. PDF N/A Human Brain-Wide Activation of Sleep Rhythms
Prefoldin 5 是一种微管相关蛋白,能够抑制Tau蛋白的聚集和神经毒性。 Bisht, A. PDF N/A Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity
大鼠暴露于自助餐厅饮食后腹侧被盖区的行为和神经改变 Lalanza, J. F. PDF N/A Behavioral and neural alterations of the ventral tegmental area by Cafeteria diet exposure in rats
眼动搜索任务与手动搜索任务中搜索成本与准确性之间的权衡 Wagner, I. PDF N/A Trade-off between search costs and accuracy in oculomotor and manual search tasks
GLE1功能障碍会破坏细胞内稳态、空间组织以及周围轴突的分支。 Zarybnicky, T. PDF N/A GLE1 dysfunction compromises cellular homeostasis, spatial organization, and peripheral axon branching
荷兰未来关键鸟类物种的病原体传播丰富度 Dellar, M. PDF N/A The future abundance of key bird species for pathogen transmission in the Netherlands
使用GEV分布纳入气候极端情况可以提高物种分布模型(SDM)在范围边缘的表现。 Fonteyn, W. PDF N/A Incorporating climatic extremes using the GEV distribution improves SDM range edge performance
柳树中的一种新型下游因子取代了祖先的性别决定基因 Wang, Y. PDF N/A A novel downstream factor in willows replaces the ancestral sex determining gene
TRENDY:基于Transformer的基因调控网络推断增强技术 Tian, X. PDF N/A TRENDY: Gene Regulatory Network Inference Enhanced by Transformer
214份玉米自交系叶片可及染色质区域的泛顺反子分析 Zhu, Y. PDF N/A Pan-cistrome analysis of the leaf accessible chromatin regions of 214 maize inbred lines
与UmV-KP4和UmV-KP6结构相关的小麦白粉菌蛋白对真菌具有毒性,并定义了真菌效应因子的新型结构家族。 de Guillen, K. PDF N/A Zymoseptoria tritici proteins structurally related to UmV-KP4 and UmV-KP6 are toxic to fungi, and define novel structural families of fungal effectors
钙调素调控的顺式和反式E-钙粘蛋白EC1-2相互作用在钙粘蛋白连接的形成、动态变化和可塑性中起着关键作用。 Bron, P. PDF N/A Calcium-modulated cis and trans E-cadherin EC1-2 interactions play a key role in formation, dynamics and plasticity of cadherin junctions
ATP门控的P2x7受体是II型听觉神经的主要通道类型,对于听觉敏感性的传出控制和噪音保护是必需的。 Liang, C. PDF N/A ATP-gated P2x7 receptor is a major channel type at type II auditory nerves and required for hearing sensitivity efferent controlling and noise protection
在自我认知的元认知中,运动与结果表征的分离 Charalampaki, A. PDF N/A Dissociation of movement and outcome representations in metacognition of agency
PEPITEM 三肽和拟肽:免疫介导条件下炎症的下一代调节剂 Saviano, A. PDF N/A PEPITEM Tripeptides and Peptidomimetics: Next-Generation Modulators of Inflammation in Immune-Mediated Conditions
真核生物中基于DAG的Dip2介导的特异性PKC信号轴的形成 Shambhavi, S. PDF N/A Emergence of Dip2-mediated Specific DAG-based PKC Signalling Axis in Eukaryotes
Asgard古菌对真核生物起源的显著贡献 Tobiasson, V. PDF N/A Dominant contribution of Asgard archaea to eukaryogenesis
EF-24的基因组发现揭示了白血病细胞中的抗肿瘤机制 Singh, A. P. PDF N/A Genomic Discovery of EF-24 Targets Unveils Antitumorigenic Mechanisms in Leukemia Cells
在膝关节屈曲和髋关节伸展任务中,股二头肌长头的远端激活程度更高,这反映了外周而非中枢运动单位特性的差异。 Albarello, J. C. d. S. PDF N/A Greater distal activation of the biceps femoris long head during knee flexion and hip extension tasks reflects differences in peripheral, not central, motor unit properties.
尽管mHTT聚集增加,Q175DN小鼠的海马备用容量增强 Solem, M. A. PDF N/A Enhanced Hippocampal Spare Capacity in Q175DN Mice Despite Elevated mHTT Aggregation
高阶转录组组织与RNA凝聚原理的综合分析 Klobucar, T. PDF N/A Integrative analysis of higher-order transcriptome organisation and RNA condensation principles
感知专长与注意力:基于深度神经网络的探索 Das, S. PDF N/A Perceptual Expertise and Attention: An Exploration using Deep Neural Networks
亚马逊生物文化遗产在气候变化下的状况 Camara-Leret, R. PDF N/A Amazonian biocultural heritage under climate change
孟加拉国代谢综合征患者血浆脂联素水平研究及治疗指征 Parul, S. S. PDF N/A Study of Plasma Adiponectin Levels in Patients with Metabolic Syndrome and Therapeutic Indication in Bangladesh
孕期压力、线粒体健康与妊娠周数之间的关系:来自美国和土耳其两项妊娠研究的发现 Huang, Q. PDF N/A Associations between prenatal distress, mitochondrial health, and gestational age: findings from two pregnancy studies in the USA and Turkey
元分析:使用磁性纳米颗粒提取的人血DNA、大肠杆菌gDNA和质粒的纯度 Tjoa, S. E. E. PDF N/A Meta-analysis: Purity of extracted human blood DNA, E. coli gDNA, and plasmid using magnetic nanoparticle
利用自体血液构建神经血管组织以模拟脑活动 Arora, R. PDF N/A Building neurovascular tissue from autologous blood for modeling brain-activity
表观遗传轨迹预测ACPA阳性个体临床类风湿性关节炎的发展:针对类风湿性关节炎预防的免疫反应靶向(TIP-RA) Prideaux, E. B. PDF N/A Epigenetic trajectory predicts development of clinical rheumatoid arthritis in ACPA+ individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA)
自主神经系统(ANS)-免疫网络在人类免疫缺陷病毒(HIV)感染者中的作用 Mueller, B. R. PDF N/A The Autonomic Nervous System (ANS)-Immune Network in People Living With HIV
mRNA疫苗激发并由Omicron变种回忆的B细胞纵向分析揭示了广泛中和沙贝病毒的抗体 Chen, X. PDF N/A Longitudinal profiling of B cells primed by mRNA vaccine and recalled by Omicron variants uncovers antibodies broadly neutralizing sarbecoviruses
RIG-I和MDA5协同识别登革病毒(DENV)的复制形式双链RNA,从而激活先天免疫反应。 Ye, S. PDF N/A RIG-I and MDA5 cooperatively recognize the DENV replicative-form dsRNA to activate innate immunity
HSV-1感染改变了MAPT剪接,并促进了阿尔茨海默病神经模型中的Tau病理 Ijezie, E. C. PDF N/A HSV-1 Infection Alters MAPT Splicing and Promotes Tau Pathology in Neural Models of Alzheimer's Disease
关于噬菌体尾部终止蛋白和尾部完成蛋白:噬菌体T5尾部近端极端的结构 Linares, R. PDF N/A About bacteriophage tail terminator and tail completion proteins: structure of the proximal extremity of siphophage T5 tail
耐气甲烷菌利用海藻和海草的代谢物来推动海洋甲烷的排放。 Hall, N. PDF N/A Aerotolerant methanogens use seaweed and seagrass metabolites to drive marine methane emissions
TaRTLEt:利用边缘检测的转录活性核糖开关追踪器 Kshatriya, S. PDF N/A TaRTLEt: Transcriptionally-active Riboswitch Tracer Leveraging Edge deTection
铜绿假单胞菌同时生产脂肽和鼠李糖脂生物表面活性剂:一种有前景的生物表面活性剂强化生物修复混合物 Jacoby, M. d. R. PDF N/A Simultaneous production of lipopeptide and rhamnolipid biosurfactants by Pseudomonas aeruginosa: A promising blend for biosurfactant-enhanced bioremediation
赋予抗真菌药物抗性的RNAi表观突变是可遗传的。 Perez-Arques, C. PDF N/A RNAi epimutations conferring antifungal drug resistance are inheritable
一种新型的PhoPQ增强的黏菌素耐药机制损害了铜绿假单胞菌的膜完整性 Hsieh, Y.-Y. P. PDF N/A A novel PhoPQ-potentiated mechanism of colistin resistance impairs membrane integrity in Pseudomonas aeruginosa
系统注释噬菌体基因组和质粒中的超变热点 Egorov, A. A. PDF N/A Systematic annotation of hyper-variability hotspots in phage genomes and plasmids
通过微血管3D血脑屏障模型揭示的恶性疟原虫出胞机制 Piatti, L. PDF N/A Pathogenic mechanisms of Plasmodium falciparum egress unveiled by a microvascular 3D blood-brain barrier model
DDX3通过与PABP1及病毒基因组非翻译区的相互作用,调控日本脑炎病毒的帽依赖性翻译。 Li, C. PDF N/A DDX3 regulates the cap-independent translation of the Japanese encephalitis virus via its interactions with PABP1 and the untranslated regions of the viral genome
无壁细菌的FtsZ形成环状结构 Kasai, T. PDF N/A FtsZ of wall-less bacteria forms ring-like structures
单个MCP在希瓦氏菌(Shewanella putrefaciens)对浮游和结构化环境中游泳的进化适应中的作用 Edelmann, D. B. PDF N/A Role of a single MCP in evolutionary adaptation of Shewanella putrefaciens for swimming in planktonic and structured environments
强烈的隔离促进了自我毁灭的合作。 Wen, L. PDF N/A Strong segregation promotes self-destructive cooperation
从黄粉虫肠道中分离塑料降解微生物 Reish, H. M. PDF N/A Isolation of Plastic Digesting Microbes from the Gastrointestinal Tract of Tenebrio Molitor
共生肠道病毒组通过Th17细胞调节肠道营养感应 Lin, F. PDF N/A Commensal gut virome regulates intestinal nutrient sensing via Th17 cells
你是我的母亲吗?:当宿主遗传和肠道微生物在非洲化蜜蜂杂交种(Apis mellifera scutellata x sspp.)中讲述不同的系统发育故事时 Soares, K. O. PDF N/A Are you my mother?: When host genetics and gut microbiota tell different phylogenetic stories in the Africanized honey bee hybrid (Apis mellifera scutellata x sspp.)
前膜和包膜蛋白对蜱传脑炎病毒结构、致病性和趋向性的影响 Rosendal, E. PDF N/A The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus
丹佛动物园狮子、老虎和鬣狗群中的SARS-CoV-2疫情 Gallichotte, E. N. PDF N/A SARS-CoV-2 outbreak in lions, tigers and hyenas at Denver Zoo
利用dCas引导的邻近标记技术在曲霉菌中进行位点特异性染色质蛋白质组学研究。 Strauss, J. PDF N/A Locus-specific chromatin proteomics using dCas-guided proximity labelling in Aspergillus nidulans.
TropD-Detector:一种基于CRISPR/LbCas12a的系统,用于快速且灵敏地筛选恰加斯病媒介和宿主中的克氏锥虫 Ortiz-Rodriguez, L. A. PDF N/A TropD-Detector: A CRISPR/LbCas12a-Based system for rapid and sensitive screening of Trypanosoma cruzi in Chagas vectors and reservoirs
一种以可重复性为重点的单细胞转录组病例对照研究的元分析方法揭示了稳健差异表达基因 Nakatsuka, N. J. PDF N/A A Reproducibility Focused Meta-Analysis Method for Single-Cell Transcriptomic Case-Control Studies Uncovers Robust Differentially Expressed Genes
坏死梭杆菌和变异梭杆菌是牛生殖道微生物群中的共生成员,可能在胎儿期就定殖于牛犊体内。 Kilama, J. PDF N/A Fusobacterium necrophorum and Fusobacterium varium are commensal members of the bovine reproductive microbiota and may colonize calf prenatally
多米尼加共和国非洲猪瘟主动和被动监测的最新情况 Schambow, R. A. PDF N/A An Update on Active and Passive Surveillance for African Swine Fever in the Dominican Republic
铜绿假单胞菌中由RNase E支架结构域介导的关键功能和关键相互作用 Geslain, S. A. M. PDF N/A Critical functions and key interactions mediated by the RNase E scaffolding domain in Pseudomonas aeruginosa
遗传兼容性和生态连通性推动抗生素抗性基因的传播 Lund, D. PDF N/A Genetic compatibility and ecological connectivity drive the dissemination of antibiotic resistance genes
主要病原菌流感嗜血杆菌在局部和全球范围内经历了普遍的重组和净化选择。 MacAlasdair, N. PDF N/A The major pathogen Haemophilus influenzae experiences pervasive recombination and purifying selection at local and global scales
利用单分子FRET技术对SARS-CoV-2 RNA聚合酶抑制剂的活性机制进行解析 Groves, D. PDF N/A Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
活性炭通过重塑肠道微生物群的代谢来改善2型糖尿病 Zhao, C.-X. PDF N/A Activated carbon ameliorates type 2 diabetes via metabolic remodeling of the gut microbiota
利用黑曲霉通过液体发酵优化甘蔗糖蜜生产柠檬酸的工艺 Amin, A. PDF N/A Optimization of citric acid production from sugarcane molasses using Aspergillus niger by submerged Fermentation
基于昏迷模式的自动对焦技术在解析细菌冷休克反应期间的单细胞动力学方面展现出卓越性能 Li, S. PDF N/A Coma pattern-based autofocusing unlocks superior performance in unravelling single-cell dynamics during bacterial cold shock response
RNA元件对于西尼罗河病毒诱导的核糖体移码的高效率是必需的 Aleksashin, N. A. PDF N/A RNA elements required for the high efficiency of West Nile Virus-induced ribosomal frameshifting
进一步表征和工程化一个11氨基酸基序以增强重组蛋白表达 Bi, J. PDF N/A Further characterization and engineering of a 11-amino acid motif for enhancing recombinant protein expression
一种流行病性Ralstonia solanacearum谱系的兴起及其宿主范围的扩展 Evseeva, D. PDF N/A Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum