| 棒状细菌荧光假单胞菌SBW25的球形mreB缺失突变体的进化救援 |
Yulo, P. R. |
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N/A |
Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25 |
| 在微型鱼类丹尼奥内拉·大脑中，催产素介导的社会偏好与社会强化奖励学习 |
Penalva, A. |
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N/A |
Oxytocin-mediated social preference and socially reinforced reward learning in the miniature fish Danionella cerebrum |
| 循环连接通过解释消除机制促进遮挡物体的识别。 |
Kang, B. |
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N/A |
Recurrent connections facilitate occluded object recognition by explaining-away |
| 果蝇母体和早期合子转录调控的演变 |
Omura, C. |
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N/A |
Evolution of maternal and early zygotic transcript regulation across Drosophila |
| T细胞牵引力表现出依赖于刺激和细胞亚型的时序模式。 |
Mustapha, F. |
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N/A |
T Cell Traction Forces show temporal patterns which Depend on Stimulation and Cell Subtype |
| 在注意力瞬盲期间评估工作记忆表征：一种比较建模方法 |
Wang, S. |
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N/A |
Evaluating Working Memory Representations during the Attentional Blink: A Comparative Modeling Approach |
| HuR通过促进多嘧啶序列结合蛋白的结合，增强SARS-CoV-2非结构蛋白在基因组5'-UTR区域的翻译。 |
Raheja, H. |
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N/A |
HuR enhances SARS-CoV-2 non-structural protein translation through the genomic 5'-UTR, by promoting polypyrimidine tract-binding protein binding |
| PPE25（Rv1787）-PE18（Rv1788）-PPE26（Rv1789）基因簇参与了结核分枝杆菌的免疫逃避。 |
Mukku, R. P. |
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The PPE25 (Rv1787)-PE18 (Rv1788)-PPE26 (Rv1789) gene cluster is involved in immune evasion by Mycobacterium tuberculosis |
| 自我评估的贝叶斯更新解释了社会支配和胜者-败者效应 |
Perkes, A. |
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Bayesian updating for self-assessment explains social dominance and winner-loser effects |
| 统一稀疏编码、预测编码和除法归一化 |
Lian, Y. |
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N/A |
Unifying sparse coding, predictive coding, and divisive normalization |
| 由致病性减弱肺炎链球菌生物合成基因突变体引发的微侵袭及免疫反应 |
Weight, C. M. |
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N/A |
Microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants |
| 有性生殖种群中有益、有害和中性突变对适应性影响的整合模型 |
Irlam, G. |
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N/A |
An integrated model of the effects on fitness of beneficial, deleterious, and neutral mutations in sexual populations |
| 雄性豆娘的Opsin基因表达可塑性和光谱敏感性可能介导了对雌性颜色形态的检测。 |
Roberts, N. S. |
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N/A |
Opsin gene expression plasticity and spectral sensitivity in male damselflies could mediate female colour morph detection |
| 翻译：光合作用对翻译机制的需求促使植物细胞器中保留了冗余的tRNA代谢 |
DeTar, R. A. |
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N/A |
Photosynthetic demands on translational machinery drive retention of redundant tRNA metabolism in plant organelles |
| 高粱1（Sorghum bicolor）气生根分泌的粘液可作为固氮菌的宿主，这些固氮菌能为植物提供大量氮素。 |
Venado, R. E. |
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N/A |
Mucilage Produced by Sorghum 1 (Sorghum bicolor) Aerial Roots Hosts Diazotrophs that Provide Significant Amounts of Nitrogen to the Plant |
| 鉴定用于改进狂犬病病毒监测的支系特异性单核苷酸多态性 |
Kumar, A. |
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Identification of clade-defining single nucleotide polymorphisms for improved rabies virus surveillance |
| 多模态子空间独立向量分析有效地捕捉了大脑结构与功能之间的潜在关系。 |
Li, X. |
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Multimodal subspace independent vector analysis effectively captures the latent relationships between brain structure and function |
| 在感染早期，一个具有转录活性的脂质囊泡包裹着注入的Chimalliviridae病毒基因组。 |
Armbruster, E. |
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A transcriptionally active lipid vesicle encloses theinjected Chimalliviridae genome in early infection |
| 人类大脑中电刺激的基因表达特征 |
Chatterjee, S. |
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N/A |
The gene expression signature of electrical stimulation in the human brain |
| 通过HCN通道对NMDA放大进行输入特异性调控在鼠L2/3层锥体神经元中的作用 |
Olah, V. J. |
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N/A |
Input-specific gating of NMDA amplification via HCN channels in mouse L2/3 pyramidal neurons |
| 活动依赖性的突触聚集在发育中的视网膜下丘脑系统中导致了眼特异性竞争的形成。 |
Zhang, C. |
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Activity-dependent synapse clustering underlies eye-specific competition in the developing retinogeniculate system |
| 短期社交隔离通过作用于下丘脑神经元，以性别和情境依赖的方式促进社交行为。 |
Zhao, X. |
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N/A |
Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner |
| OCA-B促进干细胞样CD4+ T细胞的致病性成熟1和自身免疫性脱髓鞘 |
Hughes, E. P. |
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OCA-B promotes pathogenic maturation 1 of stem-like CD4+ T cells and autoimmune demyelination |
| 大豆品种北京成功结瘤所需的Sinorhizobium fredii USDA257的功能性VI型分泌系统 |
Reyes-Perez, P. |
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The functional type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful nodulation with Glycine max cv Pekin |
| 基准测试单个降解蛋白质的鉴定，以探索古代蛋白质的最佳搜索策略 |
Rodriguez Palomo, I. |
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N/A |
Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins |
| CAT Bridge：一种从多组学数据中高效挖掘基因-代谢物关联的工具包 |
Yang, B. |
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N/A |
CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics data |
| 斑马鱼活体成像显示，在早期发育过程中，只有大约2%而非50%的运动神经元通过凋亡死亡。 |
Jia, H. |
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Zebrafish live imaging reveals only around 2% rather than 50% of motor neurons die through apoptosis during early development |
| 系统性炎症加速了在过度表达人α-突触核蛋白的帕金森病大鼠模型中的神经退行性变 |
Massaro Cenere, M. |
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Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein |
| 通过单细胞RNA测序揭示肺腺癌中化疗诱导的免疫景观重塑与代谢重编程 |
Huang, Y. |
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N/A |
Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing |
| 心理压力通过miR-335-3p/Fos信号通路扰乱破骨细胞的骨代谢。 |
Zhang, J. |
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Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast |
| 化学诱导的衰老促使人类类小胶质细胞发生功能性变化 |
Armanville, S. |
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N/A |
Chemically induced senescence prompts functional changes in human microglia-like cells |
| 聚类内分析揭示了组织特异性的突变模式 |
Choudalakis, S. |
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N/A |
Intra-clustering analysis reveals tissue-specific mutational patterns |
| 噬菌体抗性与土壤细菌贪噬菌属（Variovorax sp.）的密度增加相关，并导致群落结构的改变。 |
Castledine, M. |
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N/A |
Phage resistance is associated with density increases in the soil bacterium Variovorax sp. and results in changes to community structure |
| 通过CoVerage进行的计算机基因组监测预测并描述了SARS-CoV-2的关注变种 |
Norwood, K. |
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N/A |
In silico genomic surveillance by CoVerage predicts and characterizes SARS-CoV-2 Variants of Interest |
| 利用自然生理状况标记揭示自然啮齿动物种群中轻度干旱条件的负面影响 |
Keilani, H. S. |
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N/A |
Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura |
| 社会老龄化可以保护群居灵长类动物免受传染病的影响。 |
Siracusa, E. R. |
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N/A |
Social ageing can protect against infectious disease in a group-living primate |
| 利用7T MRI研究人脑皮层下区域的工作记忆更新过程 |
Trutti, A. C. |
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N/A |
Investigating working memory updating processes of the human subcortex using 7T MRI |
| srahunter：一个用户友好的工具，用于加速和简化从NCBI SRA下载数据 |
Bortoletto, E. |
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N/A |
srahunter: a user-friendly tool to speed up and simplify data downloading from NCBI SRA |
| 细菌裂解噬菌体生命周期的单细胞成像 |
Wedd, C. |
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N/A |
Single-cell imaging of the lytic phage life cycle in bacteria |
| 通过亲代微生物组对后代行为、海马体内的DNA甲基化和基因表达进行胎儿编程 |
Gustafson, K. L. |
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N/A |
Fetal programming by the parental microbiome of offspring behavior, and DNA methylation and gene expression within the hippocampus |
| 湖泊螺旋藻（蓝藻）的化学指纹揭示了局部分子适应性 |
Roussel, T. |
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N/A |
Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation |
| 无细胞实验揭示，HIV-1衣壳能够保护逆转录产物免受cGAS的影响。 |
Scott, T. M. |
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N/A |
Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS |
| 增殖与分化之间的失衡是微小RNA缺陷型成松果体瘤发展的基础 |
Fraire, C. R. |
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N/A |
An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma |
| 社会地位对非洲慈鲷后续求偶和交配活动的影响 |
Martashvili, A. |
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N/A |
Effects of social position on subsequent courtship and mating activity in an African cichlid |
| 豌豆蚜的母体vGluT2与胚胎mGluR3信号传递系统控制着后代翅膀二型性 |
Yuan, Y. |
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N/A |
The maternal vGluT2 and embryonic mGluR3 signaling relay system controls offspring wing dimorphism in pea aphid |
| 通过基于典型相关特征的广义最大熵进行细粒度细胞反卷积 |
Kamm, J. |
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N/A |
Fine-scale cellular deconvolution via generalized maximum entropy on canonical correlation features |
| 先天性心脏缺陷在左侧与右侧鸟类心脏神经嵴消融后表现出差异。 |
Solovieva, T. |
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N/A |
Congenital heart defects differ following left versus right avian cardiac neural crest ablation |
| 在高分辨率和准确性下，对听觉中脑的神经编码进行建模 |
Drakopoulos, F. |
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N/A |
Modeling neural coding in the auditory midbrain with high resolution and accuracy |
| 通过调节RAS蛋白的棕榈酰化来控制其信号传导 |
Zhu, J. |
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N/A |
Control of the signaling of RAS proteins by modulating their palmitoylation |
| 通过分离的大脑杏仁核回路控制先天嗅觉效价 |
Howe, J. R. |
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N/A |
Control of innate olfactory valence by segregated cortical amygdala circuits |
| 断裂诱导复制被激活，以修复SETX缺陷细胞中与R-环相关的双链断裂 |
Wu, T. |
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N/A |
Break-induced replication is activated to repair R-loop-associated double-strand breaks in SETX-deficient cells |
| 基因调控网络结构揭示了扰动效应的分布情况 |
Aguirre, M. |
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N/A |
Gene regulatory network structure informs the distribution of perturbation effects |
| 禁用链接的概率视角：它们在植物-蜂鸟群落中的普遍性及其对群落稳健性的影响 |
Duchenne, F. |
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N/A |
A probabilistic view of forbidden links: their prevalence and their consequences for the robustness of plant-hummingbird communities |
| 中央杏仁核中的效价和显著性编码 |
Kong, M.-S. |
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N/A |
Valence and Salience Encoding in the Central Amygdala |
| 强化学习指导单细胞测序解码谱系和细胞命运决定 |
Fu, Z. |
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N/A |
Reinforcement learning guides single-cell sequencing in decoding lineage and cell fate decisions |
| 生态竞争群落中的稳健共存 |
Lechon-Alonso, P. |
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N/A |
Robust coexistence in ecological competitive communities |
| 跨界鱼类：评估跨界鱼类种群的过度捕捞脆弱性 |
Gangal, M. |
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N/A |
Unbounding fish: Assessing vulnerability to overexploitation for transboundary fish populations |
| 选择强度在何时会增加进化拯救的概率？ |
Xu, K. |
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N/A |
When does the probability of evolutionary rescueincrease with the strength of selection? |
| 通过极端瓶颈清除高度有害等位基因 |
Stuart, O. P. |
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N/A |
Purging of highly deleterious alleles through an extreme bottleneck |
| MinD蛋白调控Haloferax volcanii中CetZ1的定位 |
Brown, H. J. |
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N/A |
MinD proteins regulate CetZ1 localisation in Haloferax volcanii |
| 基于结构的RyR通道操作机制：钙离子和镁离子的作用 |
Zahradnikova, A. |
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N/A |
Structure-based mechanism of RyR channel operation by calcium and magnesium ions |
| 基于新型扩增子的近全长基因组（NFLG）测序方法用于HIV-1 M组重组形式的研究 |
Moscona, R. |
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N/A |
Novel Amplicons based Method for Near-Full-Length Genome (NFLG) Sequencing of HIV-1 Group M Recombinant Forms |
| 用于分子研究的新型复制能力报告表达裂谷热病毒 |
Nogales, A. |
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N/A |
Novel replication-competent reporter-expressing Rift Valley fever viruses for molecular studies |
| 贝叶斯估计产生了反韦伯变异性 |
Prat-Carrabin, A. |
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N/A |
Bayesian estimation yields anti-Weber variability |
| 大肠杆菌的系统发育通过blaTEM-1的可变表达驱动了阿莫西林-克拉维酸的耐药性。 |
Matlock, W. |
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N/A |
E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1 |
| 通用高通量图像定量分析细胞内亚细胞结构动态及空间分布 |
Grinstaff, M. |
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N/A |
Universal high-throughput image quantification of subcellular structure dynamics and spatial distributions within cells |
| 源自患者的结肠上皮类器官揭示了儿童溃疡性结肠炎中与脂质相关的代谢功能障碍 |
Ojo, B. A. |
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N/A |
Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis |
| 肠道微生物群介导的脂质积累作为果蝇对蓝光毒性进化适应的驱动因素 |
Takada, Y. |
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N/A |
Gut microbiota-mediated lipid accumulation as a driver of evolutionary adaptation to blue light toxicity in Drosophila |
| 按需定制的主客体结合自由能：一种自动化的OneOPES协议 |
Febrer Martinez, P. |
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N/A |
Host-Guest binding free energies a la carte: an automated OneOPES protocol |
| 耳声发射而非行为测量可预测鸟类鸣叫专家的耳蜗神经频率调谐 |
Karosas, D. M. |
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N/A |
Otoacoustic emissions but not behavioral measurements predict cochlear-nerve frequency tuning in an avian vocal-communication specialist |
| 北极迁徙草食动物的活动和皮质酮的昼夜和季节性节律：多方面的研究方法 |
de Jong, M. E. |
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N/A |
Diel and seasonal rhythmicity in activity and corticosterone in an Arctic migratory herbivore: A multifaceted approach |
| CNValidatron，利用计算机视觉实现CNV调用的自动化验证 |
Montalbano, S. |
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N/A |
CNValidatron, automated validation of CNV calls using computer vision |
| 利用相关性和机制性物种分布模型预测当前和未来环境及气候变化下的虫媒疾病风险：以英国西尼罗河病毒为例的研究。 |
Withers, A. J. |
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N/A |
Using correlative and mechanistic species distribution models to predict vector-borne disease risk for the current and future environmental and climatic change: a case study of West Nile Virus in the UK. |
| 表面介导的噬菌体防御对细菌间拮抗作用产生了适应性权衡 |
Tsai, C.-E. |
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N/A |
Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism |
| 缺氧应激通过表观基因组和转录程序失调影响胶质瘤相关髓系细胞的功能。 |
Dzwigonska, M. |
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N/A |
Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs |
| 定时喂食改善了脆性X综合征小鼠模型的行为结果并减少了炎症。 |
Wang, H.-B. |
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N/A |
Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome. |
| 外周阿片受体拮抗作用可缓解芬太尼引起的心血管呼吸抑制，且无厌恶效应。 |
Ruyle, B. |
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N/A |
Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects |
| miR-92a的靶标RBFOX2的过早上调劫持了PTBP剪接，并损害了皮层神经元的分化。 |
Weissbach, S. |
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N/A |
Premature upregulation of miR-92a's target RBFOX2 hijacks PTBP splicing and impairs cortical neuronal differentiation. |
| 一份大规模的社区科学数据集揭示了北美红花植物中开花期延迟表型的趋同进化 |
McKenzie, P. F. |
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N/A |
A massive community-science dataset reveals convergent evolution of delayed flowering phenology in North American red-flowering plants |
| AAV血清型转导嗅觉感觉神经元的比较分析 |
Belfort, B. D. |
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N/A |
Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons |
| 肌动肌球蛋白收缩力是人多能干细胞诱导中胚层形成的有力抑制因素 |
Fort, L. |
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N/A |
Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells |
| 温度诱导的膜转运驱动抗体向大脑的递送 |
Du, F. |
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N/A |
Temperature-induced membrane trafficking drives antibody delivery to the brain |
| 化学定义的脂质饮食揭示了基因组最小细胞中脂质组重塑的多功能性 |
Safronova, N. |
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N/A |
Chemically defined lipid diets reveal the versatility of lipidome remodeling in genomically minimal cells |
| DNA/多核糖体相分离与细胞宽度限制共同作用，将核区分离与大肠杆菌的细胞生长耦合起来。 |
Papagiannakis, A. |
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N/A |
DNA/polysome phase separation and cell width confinement couple nucleoid segregation to cell growth in Escherichia coli |
| 多巴胺和皮质iPSC衍生的神经元在不同的帕金森病突变中显示出溶酶体和线粒体功能障碍的差异：这对蛋白质沉积与选择性细胞丢失的启示 |
Chedid, J. |
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N/A |
Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss |
| 皮层阿尔法节律从自然场景背景中插值遮挡的运动 |
Yeh, L.-C. |
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N/A |
Cortical alpha rhythms interpolate occluded motion from natural scene context |
| ReAct项目：分析来自23个不同实验室的数据，以描述在两组活动水平命题下的DNA恢复特征。 |
Gill, P. |
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N/A |
The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions |
| 人脑视觉皮层中的行波：基于模型的MEG-EEG方法 |
Grabot, L. |
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N/A |
Traveling Waves in the Human Visual Cortex: an MEG-EEG Model-Based Approach |
| 登革病毒复制型双链RNA通过RIG-I和MDA5的协同作用被识别，从而激活先天免疫反应。 |
Ye, S. |
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N/A |
Dengue virus replicative-form dsRNA is recognized by RIG-I and MDA5 cooperatively to activate innate immunity |
| 新型抗体可检测原生生物病原体、细胞黏菌和植物中的核质O-岩藻糖 |
Tiwari, M. |
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N/A |
Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants |
| 参数依赖性在可识别性中的应用：应用于Tauopathy网络建模参数化的FP-Fisher-KPP反应扩散方程 |
Rahimabadi, A. |
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N/A |
Parameter Dependence in Identifiability Applied to FP-Fisher-KPP Reaction-Diffusion Equations Parameterized for Tauopathy Network Modeling |
| 部分相关性作为绘制人脑连接中功能-结构对应关系的工具 |
Santucci, F. |
PDF |
N/A |
Partial Correlation as a Tool for Mapping Functional-Structural Correspondence in Human Brain Connectivity |
| 依赖于DNA的蛋白激酶抑制剂PI-103和Samotolisib增强CRISPR/Cas9在人类T细胞中的敲入效率 |
Dzafo, E. |
PDF |
N/A |
DNA-Dependent Protein Kinase Inhibitors PI-103 and Samotolisib Augment CRISPR/Cas9 Knockin Efficiency in Human T Cells |
| 肺炎链球菌的周质和细胞壁中的磷壁酸 |
Mai, N. |
PDF |
N/A |
Teichoic acids in the periplasm and cell envelope of Streptococcus pneumoniae |
| 放弃四极杆用于质谱碎裂分析：通过高分辨率离子迁移前体隔离实现1,000 Hz速度与100%离子利用率 |
DeBord, D. |
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N/A |
Abandoning the Quadrupole for Mass Spectrometry Fragmentation Analysis: Towards 1,000 Hz Speeds with 100% Ion Utilization Using High Resolution Ion Mobility Precursor Isolation |
| 甘蔗黄叶病毒损害了甘蔗对新蚜虫媒介Melanaphis sorghi的转录组防御反应 |
Pimenta, R. J. G. |
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N/A |
Sugarcane yellow leaf virus impairs the transcriptomic defense responses of sugarcane to its new aphid vector Melanaphis sorghi |
| 通过冷冻电镜断层成像技术可视化的AMPA受体支架复合物的原位结构与形貌 |
Held, R. G. |
PDF |
N/A |
In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET |
| 生物科学博士在性别和种族/民族方面的出版差异显著模式 |
Leap, K. |
PDF |
N/A |
Distinct patterns of bioscience doctoral publication disparities by gender and race/ethnicity |
| 大规模无意盲视实验揭示的身体检测反转效应 |
Gandolfo, M. |
PDF |
N/A |
A body detection inversion effect revealed by a large-scale inattentional blindness experiment |
| DprA招募ComM，以促进革兰氏阴性菌在自然转化过程中进行重组 |
Dalia, T. N. |
PDF |
N/A |
DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria |
| 猕猴V1和V2区中自然纹理的表征几何 |
Pavuluri, A. |
PDF |
N/A |
The representational geometry for naturalistic textures in macaque V1 and V2 |
| 冬季围栏对欧洲芦苇鹿能量消耗和运动活动的影响 |
Silovsky, V. |
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N/A |
Impact of winter enclosures on energy expenditure and movement activity of european reed deer |
| H2O2 重新利用植物的氧气感应机制来控制对氧化应激的转录反应。 |
Akter, S. |
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N/A |
H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress |
| 苯并噁嗪介导的微生物群反馈增强了拟南芥的生长和防御能力。 |
Stengele, K. |
PDF |
N/A |
Benzoxazinoid-mediated microbiome feedbacks enhance Arabidopsis growth and defense |
| 研究大麦的甲基组、其变异及其与基因组、转录组和表型变异的关联 |
Kühl, M. A. |
PDF |
N/A |
Investigating the barley methylome, its variation and association with genomic, transcriptomic, and phenotypic variation |
| NUDIX水解酶特异性靶向肌醇焦磷酸，调控磷和铁稳态，并在拟南芥中调控防御基因的表达。 |
Schneider, R. |
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N/A |
NUDIX Hydrolases Target Specific Inositol Pyrophosphates and Regulate Phosphate and Iron Homeostasis, and the Expression of Defense Genes in Arabidopsis |
| 一个基因组到蛋白质组的图谱绘制了控制蛋白质组多样性的自然变异，并预测了它们的适应性效应。 |
Jakobson, C. M. |
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N/A |
A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects |
| 评估从激酶-底物相互作用和磷酸蛋白质组学数据推断信号通路 |
Garrido-Rodriguez, M. |
PDF |
N/A |
Evaluating signaling pathway inference from kinase-substrate interactions and phosphoproteomics data |
| 含GluN2B的NMDA受体在突触中的积累介导了BDNF-TrkB信号对突触可塑性和癫痫发生的影响。 |
De Luca, P. |
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N/A |
Synaptic accumulation of GluN2B-containing NMDA receptors mediates the effects of BDNF-TrkB signalling on synaptic plasticity and in epileptogenesis |
| 奥杜瓦伊域表达下调线粒体途径：对人类大脑进化和幼态持续的意义 |
Keeney, J. G. |
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N/A |
Olduvai domain expression downregulates mitochondrial pathways: implications for human brain evolution and neoteny |
| 转录组图谱识别出两种未被识别的室管膜瘤亚型及髓母细胞瘤中的新通路 |
Arora, S. |
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N/A |
Transcriptomic landscape identifies two unrecognized ependymoma subtypes and novel pathways in medulloblastoma |
| 涉及长链非编码RNA MB3及驱动基因MYC和OTX2的电路通过调节HMGN5介导的TGF-β通路，抑制了3组髓母细胞瘤中的细胞凋亡。 |
Grandioso, A. |
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N/A |
A circuit involving the lncRNA MB3 and the driver genes MYC and OTX2 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5 |
| SIM和CCS52A1控制根毛细胞的内复制和扩展 |
Li, L. |
PDF |
N/A |
SIM and CCS52A1 control root hair cell endoreplication and expansion |
| 奥哈卡玉米（Zea mays）地方品种的气生根形成在成年阶段仍然持续，并且受土壤氮和环境湿度的影响较小。 |
Wilker, J. |
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N/A |
Aerial root formation in Oaxacan maize (Zea mays) landraces persists into the adult phase and is minimally affected by soil nitrogen and ambient humidity. |
| COmapper：通过拟南芥长读长测序实现高分辨率减数分裂交叉图谱绘制 |
Byun, D. |
PDF |
N/A |
COmapper: High-resolution mapping of meiotic crossovers by long-read sequencing in Arabidopsis |
| 利用生物弹射技术、多重CRISPR/Cas9编辑和Indel选择性PCR高效诱变玉米自交系 |
Rai, M. N. |
PDF |
N/A |
Efficient mutagenesis of maize inbreds using biolistics, multiplex CRISPR/Cas9 editing, and Indel-Selective PCR |
| 外生菌根共生在蔷薇类植物谱系中独立进化，并通过趋同基因重复实现。 |
van Beveren, F. |
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N/A |
Ectomycorrhizal symbiosis evolved independently and by convergent gene duplication in rosid lineages |
| 尖峰皮层及相连网络中的结构妥协 |
Sahlas, E. |
PDF |
N/A |
Structural compromise in spiking cortex and connected networks |
| 根据重要性和难度对人类决策进行优先排序 |
Aboalasaad, F. |
PDF |
N/A |
Prioritization of decisions by importance and difficulty in human planning |
| 使用MRIQC对未处理的人脑解剖、功能和扩散磁共振成像进行质量评估和控制 |
Hagen, M. P. |
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N/A |
Quality assessment and control of unprocessed anatomical, functional, and diffusion MRI of the human brain using MRIQC |
| 视网膜神经节细胞的不同富集构成了所提出的核心神经退行性转录程序的基础 |
Watkins, T. A. |
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N/A |
Differential enrichment of retinal ganglion cells underlies proposed core neurodegenerative transcription programs |
| 一个包含2,362份来自三大洲八所兽医教学医院的马粪微生物组的新数据集揭示了地理、品种和疾病的主导影响。 |
McAdams, Z. L. |
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N/A |
A novel dataset of 2,362 equine fecal microbiomes from eight veterinary teaching hospital on three continents reveals dominant effects of geography, breed, and disease |
| 新生RNA标记化合物5-乙炔基尿苷（EU）在海葵Nematostella vectensis的DNA中整合。 |
Kjosavik, M. A. |
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N/A |
The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in the sea anemone Nematostella vectensis |
| 预测肽结合特异性中单个残基效应的计算方法的互补评估 |
Ayyildiz, M. |
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N/A |
Complementary evaluation of computational methods for predicting single residue effects on peptide binding specificities |
| 仔细审查脂质利用会破坏两性霉素B在利什曼原虫杜氏临床分离株中的反应性 |
Pradhan, S. |
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N/A |
Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani |
| 根瘤菌属豆科植物天然种群中质粒传递动力学与伙伴质量的进化 |
Vereau Gorbitz, D. |
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N/A |
Plasmid transmission dynamics and evolution of partner quality in a natural population of Rhizobium leguminosarum |
| 一种实用且安全的氮芥对角膜损伤的模型 |
Sandoval-Castellanos, A. M. |
PDF |
N/A |
A Practical and Safe Model of Nitrogen Mustard Injury in Cornea |
| 通过使用轴向电极，提升光纤神经接口在光遗传学和电生理学中的去简并性 |
Sui, K. |
PDF |
N/A |
Lifting the degeneracy of optical fiber neural interfaces for optogenetics and electrophysiology by using axialtrodes |
| 视网膜色素变性突变型光感受器神经元中ER聚集导致突触蛋白失衡 |
Thompson, S. |
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N/A |
ER Aggregation Causes Synaptic Protein Imbalance in Retinitis Pigmentosa Mutant Photoreceptor Neurons |
| 在酵母中重现小鼠基因进化军备竞赛揭示了SLXL1/SLX与SLY1/2竞争结合Spindlins。 |
Arlt, M. F. |
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N/A |
Reenacting a mouse genetic evolutionary arms race in yeast reveals SLXL1/SLX compete with SLY1/2 for binding to Spindlins. |
| 在人类世，遗传多样性的丧失将在栖息地破坏结束后仍持续很长时间。 |
Mualim, K. S. |
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N/A |
Genetic diversity loss in the Anthropocene will continue long after habitat destruction ends |
| 一种快速、简便且经济的分离核糖体和翻译机器用于结构和功能研究的方法 |
Erath, J. |
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N/A |
A rapid, facile, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies |
| 空间转录组学分析揭示了晚期卵巢透明细胞癌的肿瘤内异质性：上皮-间质梯度的存在 |
Truong Le, T. |
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N/A |
Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient |
| 高级卵巢透明细胞癌的空间转录组分析揭示了肿瘤内上皮-间质梯度的异质性 |
Truong Le, T. |
PDF |
N/A |
Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient |
| 高级卵巢透明细胞癌的空间转录组学分析揭示了肿瘤内上皮-间质梯度的异质性 |
Truong Le, T. |
PDF |
N/A |
Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient |
| 烟酰胺代谢重编程驱动胶质母细胞瘤细胞的可逆性衰老 |
Narayanan, A. |
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N/A |
Nicotinamide Metabolism Reprogramming Drives Reversible Senescence of Glioblastoma Cells |
| 空间生物学的保守原则定义了肿瘤异质性及对免疫治疗的反应 |
Behera, V. |
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N/A |
Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapy |
| 苦味受体激动剂可诱导甲状腺乳头状癌凋亡 |
Wei, K. |
PDF |
N/A |
Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer |
| ALDH1亚型特异性抑制剂靶向三阴性乳腺癌中的关键细胞群体 |
PEREZ, M. |
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N/A |
ALDH1 subtype-specific inhibitor targets key cell populations in triple negative breast cancer |
| Hv1质子通道缺陷增强巨噬细胞抗原呈递及胶质瘤中的抗肿瘤反应 |
Zheng, J. |
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N/A |
Deficiency of Hv1 Proton Channel Enhances Macrophage Antigen Presentation and Anti-Tumor Responses in Glioma |
| 人工选择与皮肤微生物群独立预测寄生虫抗性 |
Kramp, R. D. |
PDF |
N/A |
Artificial Selection and the Skin Microbiome Independently Predict Parasite Resistance |
| 邻接算法中的混合种群：一种五分类群的几何分析 |
Zhang, J. Z. |
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N/A |
Admixed populations in the neighbor-joining algorithm: a geometric analysis with five taxa |
| 通过位点特异性掺入基于转子的荧光非规范氨基酸，在活细胞中实时可视化蛋白质微环境变化，具有高空间分辨率 |
Yang, S. |
PDF |
N/A |
Real-Time Visualization of Protein Microenvironment Changes with High Spatial Resolution in Live Cells via Site-Specific Incorporation of Rotor-Based Fluorescent Noncanonical Amino Acids |
| 具有可调特性的双面蛋白质纳米材料的计算设计 |
Rankovic, S. |
PDF |
N/A |
Computational design of bifaceted protein nanomaterials with tailorable properties |
| 快速微流控灌注系统能够控制由Na+/H+交换体NHE1调节的细胞内pH动态变化。 |
Tran, Q. D. |
PDF |
N/A |
Rapid microfluidic perfusion system enables controlling dynamics of intracellular pH regulated by Na+/H+ exchanger NHE1 |
| p-ClustVal：一种新颖的p进制方法用于增强高维单细胞RNA测序数据的聚类分析 |
Sharma, P. |
PDF |
N/A |
p-ClustVal: A Novel p-adic Approach for Enhanced Clustering of High-Dimensional scRNASeq Data |
| 生成式人工智能在药物发现中的应用：基于GPT-2和LSTM模型的EGFR抑制剂设计 |
Dasser, O. |
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N/A |
Generative AI for Drug Discovery: A GPT-2 and LSTM Based Models for Designing EGFR Inhibitors |
| 利用SearchNovo弥合数据库搜索与从头肽段测序之间的差距 |
Xia, J. |
PDF |
N/A |
Bridging the Gap between Database Search and De Novo Peptide Sequencing with SearchNovo |
| LP-Micro通过利用微生物生物标志物及其随时间变化的影响，提供可解释的疾病结果预测。 |
Dai, Y. |
PDF |
N/A |
LP-Micro Offers Interpretable Disease Outcome Prediction by Leveraging Microbial Biomarkers and Their Time-Varying Effects |
| 对人类蛋白质组功能注释的纵向分析揭示了持续的高偏差 |
Phan, A. |
PDF |
N/A |
A Longitudinal Analysis of Function Annotations of the Human Proteome Reveals Consistently High Biases |
| 使用群论和对称元素建模心电图（ECG）波形 |
Frueh, S. J. |
PDF |
N/A |
Modeling Electrocardogram (ECG) Waveforms Using Group Theory and Symmetry Elements |
| CryoLike：一个用于冷冻电镜图像到结构似然计算的Python包 |
Tang, W. S. |
PDF |
N/A |
CryoLike: A python package for cryo-electron microscopy image-to-structure likelihood calculations |
| 特化细胞和转运蛋白介导慈鲷幼体皮肤吸收环境肽。 |
Con, P. |
PDF |
N/A |
Specialized cells and transporters mediate integument-absorption of environmental peptides in cichlids larvae. |
| 火星磁场和重力场对秀丽隐杆线虫多代的影响 |
Akinosho, A. |
PDF |
N/A |
Effects of Martian magnetic and gravitational fields across multiple generations of the nematode C. elegans |
| 冻结区动力学的数学建模：朝着在冷冻治疗中使用热成像仪的方向发展 |
Ivakhnenko, O. V. |
PDF |
N/A |
Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy |
| 竞争性互动塑造了跨物种的大脑动力学和计算能力 |
Luppi, A. I. |
PDF |
N/A |
Competitive interactions shape brain dynamics and computation across species |
| 纤维微观结构分位数（FMQ）回归：一种分析从外围到核心的白质束的新型统计方法 |
Lan, Z. |
PDF |
N/A |
Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core |
| 纤维微观结构分位数（FMQ）回归：一种分析从外围到核心的白质束的新型统计方法 |
Lan, Z. |
PDF |
N/A |
Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core |
| 通过PANDORA-seq技术揭示的阿尔茨海默病小鼠模型中线粒体小RNA变化与溶酶体活性增加相关 |
Zhang, X. |
PDF |
N/A |
Mitochondrial small RNA alterations associated with increased lysosome activity in an Alzheimer's Disease Mouse Model uncovered by PANDORA-seq |
| 学术成就与心理健康：贫困儿童前额叶-顶叶-默认模式网络耦合的悖论 |
Pacheco, S. |
PDF |
N/A |
Academic Success and Mental Health: The Paradox of Frontoparietal-Default Mode Network Coupling among Children Facing Poverty |
| 可诱导的胰腺REG/Reg异构体，而非组成型异构体，受肠道微生物群和胰腺疾病调控。 |
Zhou, Y. |
PDF |
N/A |
Inducible, but not constitutive, pancreatic REG/Reg isoforms are regulated by intestinal microbiota and pancreatic diseases |
| 人类腺样体的单细胞转录组分析揭示了气道微褶细胞的分子特征 |
Alvarez-Arguedas, S. |
PDF |
N/A |
Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells |
| 在基因流动较高的局部适应种群中，遗传分化主要受限于染色体倒位和假定的着丝粒。 |
Akopyan, M. |
PDF |
N/A |
Genetic differentiation is constrained to chromosomal inversions and putative centromeres in locally adapted populations with higher gene flow |
| 利用病原体防御权衡管理作物害虫对生物防治产生抗性的风险。 |
Mangan, R. M. |
PDF |
N/A |
Exploiting pathogen defence trade-offs to manage risks of crop pests evolving resistance to biocontrol. |
| 对贝加尔湖海豹及其他海豹科动物进行全基因组重测序，以一窥其遗传多样性、种群历史及系统发育关系。 |
Nebenfuehr, M. |
PDF |
N/A |
Whole-genome re-sequencing of the Baikal seal and other phocid seals for a glimpse into their genetic diversity, demographic history, and phylogeny |
| 在单核苷酸分辨率下，人群之间人类肠道微生物组的基因组多样性和基础代谢变异 |
Dong, Q. |
PDF |
N/A |
Genomic diversity and underlying metabolic variations of the human gut microbiome between populations at single nucleotide resolution |
| 加拿大卡尔加里市弓河中微塑料的九个分离株的完整基因组序列 |
Goff, K. L. |
PDF |
N/A |
Complete genome sequences of nine isolates from microplastics in the Bow River, Calgary, Canada |
| 开发用于人C肽分泌的片上荧光各向异性免疫分析法揭示了示踪剂优化的通用路线图 |
Wang, Y. |
PDF |
N/A |
Development of an on-chip fluorescence anisotropy immunoassay for human C-peptide secretion reveals a general roadmap for tracer optimization |
| 多通道漏斗适应传感管（MFAST）用于寄生虫的简单和双检测 |
Peng, R. |
PDF |
N/A |
Multi-Channel Funnel Adapted Sensing Tube (MFAST) for the Simple and Duplex Detection of Parasites |
| 基于注意力机制的深度神经网络模型，用于从多组学数据中在单细胞水平检测顺式调控元件 |
Murakami, K. |
PDF |
N/A |
An attention-based deep neural network model to detect cis-regulatory elements at the single-cell level from multi-omics data |
| ABCB4的膜依赖性动态变化及双重转运机制：分子动力学模拟的见解 |
Crespi, V. |
PDF |
N/A |
Membrane-Dependent Dynamics and Dual Translocation Mechanisms of ABCB4: Insights from Molecular Dynamics Simulations |
| 等离子体膜的纳米级曲率通过核变形和破裂调节机械适应性。 |
Francis, E. A. |
PDF |
N/A |
Nanoscale curvature of the plasma membrane regulates mechanoadaptation through nuclear deformation and rupture |
| 关联无序激活域集合与基因表达水平 |
Flores, E. |
PDF |
N/A |
Correlating Disordered Activation Domain Ensembles with Gene Expression Levels |
| 无标度群体行为和上皮活性固体中的巨幅波动 |
Shen, Y. |
PDF |
N/A |
Scale-free flocking and giant fluctuations in epithelial active solids |
| 电刺激期间猴子V1区局部场电位的层特异性动力学 |
Lee, S. |
PDF |
N/A |
Layer-specific dynamics of local field potentials in monkey V1 during electrical stimulation |
| 通过AFM纳米动态力学分析鉴定出的胶原超微结构粘弹性行为 |
Asgari, M. |
PDF |
N/A |
Ultrastructural viscoelastic behavior of collagen identified by AFM nano-dynamic mechanical analysis |
| 基于功能性单细胞方法理解恩杂鲁胺耐药性的发展 |
Xue, C. |
PDF |
N/A |
Understanding the development of enzalutamide resistance based on a functional single-cell approach |
| 氯胺酮代谢物（2R,6R）-羟基去甲氯胺酮诱导的海马突触快速增强持久地预处理突触可塑性 |
Brown, K. A. |
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N/A |
RAPID HIPPOCAMPAL SYNAPTIC POTENTIATION INDUCED BY KETAMINE METABOLITE (2R,6R)-HYDROXYNORKETAMINE PERSISTENTLY PRIMES SYNAPTIC PLASTICITY |
| 转录组分析揭示了牛结核病易感性的品种特异性免疫特征 |
Kumar, R. |
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N/A |
Transcriptomic profiling identifies breed-specific immune signatures of Tuberculosis susceptibility in cattle |
| 在啮齿动物中，背侧海马和腹侧海马分别靶向内侧前额叶皮层的不同细胞群体 |
Aleman-Andrade, P. |
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Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents |
| 针对乙酰基转移酶NAT10进行靶向治疗，可以纠正人类额颞叶神经元的病理变化，并在果蝇体内tau蛋白病变的模型中延长寿命。 |
Paonessa, F. |
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N/A |
Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal neurons and extends lifespan in an in vivo Drosophila tauopathy model |
| 视交叉上核的连接组组织 |
Liu, J. |
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N/A |
Connectomic Organization of the Suprachiasmatic Nucleus |
| 探索在HIV-1感染的体内模型中，胞外囊泡、树突状细胞免疫受体与microRNA-155之间的关系，以理解疾病并开发新疗法 |
Boucher, J. |
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N/A |
Exploring the Relationship Between Extracellular Vesicles, the Dendritic Cell Immunoreceptor and microRNA-155 in an In Vivo Model of HIV-1 Infection to Understand the Disease and Develop New Treatments |
| Cdc42的缺失导致小鼠视杯形态发生异常及小眼症 |
Hofstetter, K. S. |
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N/A |
Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse |
| 古老而依然存活的杨树克隆体“潘多”中的体细胞突变镶嵌图 |
Pineau, R. |
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N/A |
Mosaic of Somatic Mutations in the Ancient and Still-Living Aspen Clone, Pando |
| 十倍扩展的基质辅助激光解吸电离质谱成像技术，以500纳米分辨率对组织和细胞进行成像 |
Xie, C. |
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Ten-Fold Expansion MALDI Mass Spectrometry Imaging of Tissues and Cells at 500 nm Resolution |
| PSKH1激酶活性通过别构结合Ca2+传感器蛋白而受到差异性调节 |
Horne, C. |
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PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins |
| THRESHOLD：一种综合性的转录组分析工具，用于评估基因饱和度及其在疾病进展中的影响 |
Gammell, F. M. |
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THRESHOLD: A Comprehensive Transcriptomic Analysis Tool for Evaluating Gene Saturation and Impact in Disease Progression |
| 利用原代人神经干细胞和祖细胞模拟胶质瘤的瘤内异质性 |
Gao, D. |
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N/A |
Modeling Glioma Intratumoral Heterogeneity with Primary Human Neural Stem and Progenitor Cells |
| KRAS G12突变等位基因通过FOXO1调控谷氨酰胺代谢的差异性 |
Ber, S. |
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KRAS G12 mutant alleles differentially control glutamine metabolism via FOXO1 |
| 前额叶抑制在被动应对行为中的关键作用：慢性压力与速效抗抑郁药 |
Fong, T. H. |
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Key contribution of prefrontal inhibition to passive coping behaviour: chronic stress and fast-acting antidepressant |
| 嗅觉中的数据科学 |
agarwal, v. K. |
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N/A |
Data Science in Olfaction |
| scAGCI：一种基于锚点图的细胞聚类方法，用于从整合的单细胞RNA测序（scRNA-seq）和单细胞ATAC测序（scATAC-seq）数据中进行细胞聚类。 |
Dong, Y. |
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N/A |
scAGCI: an anchor graph-based method for cell clustering from integrated scRNA-seq and scATAC-seq data |
| 控制生物分子凝聚物中界面蛋白质的吸附、解吸和聚集 |
Visser, B. |
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N/A |
Controlling interfacial protein adsorption, desorption and aggregation in biomolecular condensates |
| Capicua在德国小蠊卵巢中维持前后轴 |
Elshaer, N. |
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N/A |
Capicua maintains anterior-posterior axis in Blattella germanica ovaries |
| 温度依赖性和性别特异性的表型可塑性在Heliconius charithonia中 |
Seixas, F. A. |
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N/A |
Temperature-dependent and sex-specific phenotypic plasticity in Heliconius charithonia |
| 在分化中的晶状体纤维细胞中，核仁核糖体RNA的持续合成一直持续到突然的核降解，这是实现眼睛晶状体透明性所必需的。 |
Rayee, D. |
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N/A |
Continuous nucleolar ribosomal RNA synthesis in differentiating lens fiber cells until abrupt nuclear degradation required for ocular lens transparency |
| 整合的局部和系统性交流因素调控发育性造血过程中新生造血祖细胞的逃逸 |
Shalaby, C. |
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N/A |
Integrated local and systemic communication factors regulate nascent hematopoietic progenitor escape during developmental hematopoiesis |
| 环境线索影响河狸筑坝活动中建筑活动的时机和地点 |
Kennedy, J. R. |
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Environmental cues influence timing and location ofconstruction activity in a beaver damming complex |
| 生态和社会因素导致埋葬甲虫中两性间的亲代抚育行为存在差异。 |
Ma, D. |
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N/A |
Ecological and social factors lead to variation in parental care between sexes in a burying beetle |
| 在序列学习任务中，人类是资源理性的预测者 |
Ferdinand, V. |
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N/A |
Humans are resource-rational predictors in a sequence learning task |
| AnimalMotionViz：一种利用计算机视觉技术追踪和可视化动物运动模式的交互式软件工具 |
De Castro, A. L. |
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N/A |
AnimalMotionViz: an interactive software tool for tracking and visualizing animal motion patterns using computer vision |
| 执行控制可以查询隐藏的人类记忆 |
Zhao, C. |
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Executive control can query hidden human memories |
| 人类前驱期和早期帕金森病及大鼠模型中的纵向神经黑色素变化 |
Perot, J.-B. |
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N/A |
Longitudinal neuromelanin changes in prodromal and early Parkinson's disease in humans and rat model |
| 诱导神经元的转录特征可区分病毒学抑制的HIV感染者与非HIV感染者 |
Ostermann, P. N. |
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A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV |
| 骨髓源性的β-己糖胺酶对神经健康和溶酶体功能至关重要：对Sandhoff病的启示 |
Tsourmas, K. I. |
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Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff disease |
| 严重脊髓性肌萎缩症中D-和L-氨基酸失衡调节谷氨酸能神经传递。 |
Hassan, A. |
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Dysregulated balance of D- and L-amino acids modulating glutamatergic neurotransmission in severe spinal muscular atrophy. |
| 线性化与预测：一种基于储备计算的脑数字孪生方法 |
Di Antonio, G. |
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N/A |
Linearizing and forecasting: a reservoir computing route to digital twins of the brain |
| 视觉工作记忆中边界或独立特征的保持是任务依赖的 |
Cao, R. |
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Maintenance of Bound or Independent Features in Visual Working Memory is Taskdependent |
| 间歇性干扰电流刺激对迷走神经中器官特异性纤维时空激活的控制 |
Rossetti, N. |
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N/A |
Control of spatiotemporal activation of organ-specific fibers in the vagus nerve by intermittent interferential current stimulation |
| 捕捉生物物理神经模型中的动态涌现结构 |
Milinkovic, B. |
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N/A |
Capturing the emergent dynamical structure in biophysical neural models |
| 捕捉生物物理神经模型中的新兴动力学结构 |
Milinkovic, B. |
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N/A |
Capturing the emergent dynamical structure in biophysical neural models |
| 内皮细胞Nrf2调控系统性损伤后的神经炎症 |
Zou, H. |
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N/A |
Endothelial cell Nrf2 controls neuroinflammation following a systemic insult |
| Opto2P-FCM：一种基于MEMS的微型双光子显微镜，具有双光子图案化光遗传刺激功能 |
Futia, G. L. |
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N/A |
Opto2P-FCM: A MEMS based miniature two-photon microscope with two-photon patterned optogenetic stimulation |
| 在蝙蝠卡罗利亚（Carollia perspicillata）中，听觉阈值因性别而异，但与年龄无关。 |
Molano, O. |
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N/A |
Hearing thresholds in the bat Carollia perspicillata vary by sex but not age |
| 语音编码在衰老和失语症中的时空动力学 |
Kries, J. |
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N/A |
The spatio-temporal dynamics of phoneme encoding in aging and aphasia |
| 利用空间转录组学和类器官技术定义猪母胎界面细胞多样性 |
McCutcheon, C. |
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N/A |
Defining Cellular Diversity at the Swine Maternal-Fetal Interface Using Spatial Transcriptomics and Organoids |
| 自噬在生殖系干细胞中是可有可无的，但在果蝇卵巢生态位中维持帽细胞则需要自噬。 |
Nilangekar, K. S. |
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Autophagy is dispensable in germline stem cells but is required in the cap cells for their maintenance in the Drosophila ovarian niche |
| 干细胞和祖细胞的增殖由细胞类型特异性的周期蛋白D基因独立调控。 |
Lush, M. E. |
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Stem and progenitor cell proliferation are independently regulated by cell type-specific cyclinD genes |
| 细胞增殖的局部控制是斑马鱼神经丘再生的基础 |
Lavalle, N. G. |
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N/A |
Local control of cellular proliferation underlies neuromast regeneration in zebrafish |
| 氧气水平改变牛早期胚胎的能量代谢 |
Boskovic, N. |
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N/A |
Oxygen level alters energy metabolism in bovine preimplantation embryos |
| 背外侧前额叶皮层神经活动的损伤在帕金森病早期即出现 |
Hjelle, N. |
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N/A |
Impairment of Neuronal Activity in the Dorsolateral Prefrontal Cortex Occurs Early in Parkinsonism |
| 星形胶质细胞TrkB.T1缺陷破坏了谷氨酸能突触的形成以及星形胶质细胞与突触的相互作用。 |
Pinkston, B. T. C. |
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N/A |
Astrocyte TrkB.T1 deficiency disrupts glutamatergic synaptogenesis and astrocyte-synapse interactions. |
| Shc1与Frs2和Shp2合作，在FGF诱导的晶状体发育中招募Grb2 |
Wang, Q. |
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Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development |
| 经皮迷走神经刺激在感知决策过程中提高了错误后的准确性 |
Su, S. |
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Transcutaneous Vagus Nerve Stimulation Boosts Post-Error Accuracy During Perceptual Decision-Making |
| 针对果蝇中央复合体的细胞类型特异性驱动线及其用于研究神经肽表达和睡眠调控的应用 |
Wolff, T. |
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N/A |
Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation |
| 未甲基化全突变携带者的转录组分析表明TET3在脆性X综合征中FMR1 CGG重复扩增甲基化动力学中的作用 |
Farmiloe, G. |
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N/A |
Transcriptomic profiling of unmethylated full mutation carriers implicates TET3 in FMR1 CGG repeat expansion methylation dynamics in Fragile X syndrome |
| 利用生长素诱导降解子2技术揭示单个突触快速蛋白质清除的急性后果 |
Elbaum, L. |
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N/A |
Revealing Acute Consequences of Rapid Protein Elimination at Individual Synapses using Auxin-Inducible Degron 2 Technology |
| 通过自我调节体感活动增强人体感觉运动整合 |
Iwama, S. |
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N/A |
Enhanced human sensorimotor integration via self-modulation of the somatosensory activity |
| 使用具有分化簇基因启动子的病毒载体，以靶向大脑中的特定细胞类型 |
Uesaka, N. |
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N/A |
Viral vectors with cluster of differentiation gene promoters to target specific cell types in the brain |
| 阿尔茨海默病5XFAD小鼠的空间记忆通过XPO1抑制剂KPT-330得到增强 |
Wong, S. Q. |
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N/A |
Spatial memory in Alzheimer's disease 5XFAD mice is enhanced by XPO1 inhibitor KPT-330 |
| 视觉对象优化头部方向编码 |
Siegenthaler, D. |
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N/A |
Visual objects refine head direction coding |
| 代理体感图谱平铺视觉皮层 |
Hedger, N. |
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N/A |
Vicarious Somatotopic Maps Tile Visual Cortex |
| 实验室间微球免疫测定法的协调：用于干燥血斑和口腔液体中SARS-CoV-2抗体检测 |
DeRosa, K. L. |
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N/A |
Inter-laboratory harmonization of microsphere immunoassays for SARS-CoV-2 antibody detection in dried blood spots and oral fluids |
| 工程化蛋白质去稳定化逆转了内在免疫逃避，以实现候选疫苗泛株KSHV和SARS-CoV-2抗原 |
Wan, L. |
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N/A |
Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens |
| 真菌性脑膜炎病原体的表型景观揭示了其独特的生物学特性 |
Boucher, M. |
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N/A |
Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology |
| 单细胞转录组学揭示了皮肤细胞特异性的抗真菌免疫反应，以及新兴真菌病原体白色念珠菌的IL-1Ra- IL-1R免疫逃避策略 |
Balakumar, A. |
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N/A |
Single-Cell Transcriptomics Unveils Skin Cell Specific Antifungal Immune Responses and IL-1Ra- IL-1R Immune Evasion Strategies of Emerging Fungal Pathogen Candida auris |
| MIIST305 能够减轻胃肠道急性放射综合征损伤，并改善放射引起的肠道菌群失调。 |
Mitra, D. |
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N/A |
MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosis |
| 一种针对微生物组衍生疗法的靶向发现和表征的理性方法 |
Krause, L. |
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N/A |
A rational approach for the targeted discovery and characterisation of microbiome-derived therapeutics |
| HPAIV H5N1在生牛奶、废水和表面上的环境稳定性 |
Kaiser, F. |
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N/A |
Environmental stability of HPAIV H5N1 in raw milk, wastewater and on surfaces |
| 进化距离较远的细菌之间抗生素抗性基因的转移 |
Parras-Molto, M. |
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N/A |
The transfer of antibiotic resistance genes between evolutionary distant bacteria |
| 被遗忘的迷幻剂：2C-B和psilocybin给药后脑组织的空间时间映射 |
Mallaroni, P. |
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N/A |
The forgotten psychedelic: Spatiotemporal mapping of brain organisation following the administration of 2C-B and psilocybin |
| 功能性超声成像揭示了临床脊髓刺激的激活特性 |
Lim, K. |
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N/A |
Functional Ultrasound Imaging Reveals Activation Properties of Clinical Spinal Cord Stimulation |
| 人类在嘈杂环境中对语音感知的神经功能和因果机制 |
Ceravolo, L. |
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N/A |
Functional and causal neural mechanisms of human voice perception in noisy situations |
| 基于连接组学的预测模型：一般和特定认知控制的预测模型 |
Qu, S. |
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N/A |
Connectome-based Predictive Models of General and Specific Cognitive Control |
| 人类短连合纤维比长纤维更细，且髓鞘化程度较低。 |
Ruthig, P. |
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N/A |
Human short association fibers are thinner and less myelinated than long fibers |
| 一种主动电感应的端到端模型 |
Turcu, D. |
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N/A |
An end-to-end model of active electrosensation |
| 帕金森病在运动准备期间扰乱了前辅助运动区的神经调节 |
Hendrix, C. M. |
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N/A |
Parkinsonism disrupts neuronal modulation in the pre-supplementary motor area during movement preparation |
| Arc通过细胞外囊泡介导细胞间tau传递 |
Tyagi, M. |
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N/A |
Arc mediates intercellular tau transmission via extracellular vesicles |
| Bcl11b通过细胞自主、非细胞自主和亚细胞机制调控小脑下投射神经元的轴突发育 |
Itoh, Y. |
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N/A |
Bcl11b orchestrates subcerebral projection neuron axon development via cell-autonomous, non-cell-autonomous, and subcellular mechanisms |
| 听觉带状皮层中对侧编码的分层涌现 |
Johnson, J. S. |
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N/A |
Hierarchical emergence of opponent coding in auditory belt cortex |
| 大麻二酚逆转了精神分裂症小鼠模型中的小胶质细胞激活、小清蛋白中间神经元和神经元周围网的损失。 |
Rodrigues da Silva, N. |
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N/A |
Cannabidiol reverses microglia activation and loss of parvalbumin interneurons and perineuronal nets in a mouse model of schizophrenia |
| 催产素神经元在社交和非社交环境中，通过状态依赖的信号传递，调控产热和行为觉醒的转变。 |
Vandendoren, M. |
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N/A |
Oxytocin neurons signal state-dependent transitions to thermogenesis and behavioral arousal in social and non-social settings. |
| 关系是资源还是负担？依恋风格、关系质量和伴侣间应对与浪漫伴侣在场时急性心理社会压力的关联 |
Gallistl, M. |
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N/A |
Relationship as resource or burden? Associations of attachment style, relationship quality and dyadic coping with acute psychosocial stress in the presence of the romantic partner |
| α-突触核蛋白病理进展的网络分析揭示p21激活激酶作为脆弱性的调节因子 |
Vatsa, N. |
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N/A |
Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability |
| 一种具有增强信噪比性能的128通道接收阵列，用于10.5特斯拉脑部成像 |
Lagore, R. L. |
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N/A |
A 128-channel receive array with enhanced SNR performance for 10.5 tesla brain imaging |
| 40 Hz光刺激恢复了阿尔茨海默病模型小鼠早期脑动力学改变及联想记忆 |
Aguilera, M. |
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N/A |
40 Hz light stimulation restores early brain dynamics alterations and associative memory in Alzheimer's disease model mice |
| 共享和个体体验的神经相关性 |
Coppola, P. |
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N/A |
The neural correlates of shared and individual experience |
| 伏隔核中的5-HT2C受体限制了MDMA的奖赏效应。 |
Pomrenze, M. B. |
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N/A |
5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA |
| 适当选择参考电极并进行重新参考，以减轻单脉冲电刺激数据中的偏差 |
Huang, H. |
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N/A |
Proper reference selection and re-referencing to mitigate bias in single pulse electrical stimulation data |
| 干扰素介导的自然杀伤细胞激活与SARS-CoV-2感染期间有限的病毒中和广度相关 |
de los Rios Kobara, I. |
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N/A |
Interferon-mediated NK cell activation is associated with limited neutralization breadth during SARS-CoV-2 infection |
| Wag31，一种膜系绳，对分枝杆菌中的脂质稳态至关重要。 |
Kapoor, Y. |
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N/A |
Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria |
| 鱼类作为河流抗菌素耐药性监测的哨兵效果不佳 |
Tskhay, F. |
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N/A |
Fish are poor sentinels for surveillance of riverine AMR |
| 多酚重塑微生物群落可减少甲烷排放 |
McGivern, B. B. |
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N/A |
Polyphenol rewiring of the microbiome reduces methane emissions |
| 空间的重要性：受移动限制的虚拟行人会影响个人的避让行为 |
Nikmanesh, M. |
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N/A |
Space matters: virtual pedestrians with mobility constraints affect individuals' avoidance behaviours |
| 酮症通过改善生物能量代谢提升抗氧化能力并增强神经功能：一项1H磁共振波谱研究 |
van Nieuwenhuizen, H. |
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N/A |
Ketosis Elevates Antioxidants and Enhances Neural Function Through Improved Bioenergetics: A 1H MR Spectroscopy Study |
| 活体双光子荧光显微镜中的自适应光学校正与神经场 |
Kang, I. |
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N/A |
Adaptive optical correction in in vivo two-photon fluorescence microscopy with neural fields |
| 局部姿势变化会在关节、躯干和面部周围引发广泛而多样的皮肤伸展。 |
Rupani, M. |
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N/A |
Local postural changes elicit extensive and diverse skin stretch around joints, on the trunk, and the face |
| 基于生物性别（男性与女性）对受试者进行分组的局限性及新方法：从伏隔核核心内多巴胺诱导的精神兴奋剂活性中获得的启示。 |
Job, M. O. |
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N/A |
Limitations of grouping subjects based on biological sex (males versus females) and a new approach: insights from intra-nucleus accumbens core dopamine-induced psychostimulant activity. |
| 针对小麦叶际细菌的新型噬菌体携带DNA修饰和单链断裂 |
Dougherty, P. E. |
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Novel bacteriophages targeting wheat phyllosphere bacteria carry DNA modifications and single-strand breaks |
| 通过恢复衰老的成骨前体细胞来促进骨修复 |
Reeves, J. |
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Rejuvenating aged osteoprogenitors for bone repair |
| Zyxin的缺失减少了内皮炎症并减轻了动脉粥样硬化 |
Huang, H. |
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Deletion of Zyxin Reduces Endothelial Inflammation and Mitigates Atherosclerosis |
| 在侵袭和相关吞噬过程中，会形成一个独特的PI(4,5)P2区室。 |
Durgan, J. |
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A distinctive PI(4,5)P2 compartment forms during entosis and related engulfment processes |
| 由于上皮-间质转化导致的化疗耐药性是由异常的脂质代谢平衡引起的。 |
Matsumoto, A. |
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Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance |
| NIPBL和STAG1通过提供差异化的DNA-凝聚素亲和力来实现环挤压。 |
van Wee, R. |
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NIPBL and STAG1 enable loop extrusion by providing differential DNA-cohesin affinity |