| ADP-核糖通过重塑嘌呤和嘧啶代谢触发神经元铁死亡 |
Yuan, L. |
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N/A |
ADP-ribose triggers neuronal ferroptosis by rewiring purine and pyrimidine metabolism |
| 去泛素化抑制剂与SARS-CoV-2木瓜样蛋白酶结合的活性分析及其在鼠感染模型中的抗病毒功效 |
Choudhary, S. |
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N/A |
Activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease with antiviral efficacy in murine infection model |
| 实验微生物群落中的宏观生态模式 |
Shoemaker, W. R. |
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N/A |
Macroecological patterns in experimental microbial communities |
| 利用AlphaFold揭示hERG通道构象状态的秘密 |
Ngo, K. |
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N/A |
Harnessing AlphaFold to reveal hERG channel conformational state secrets |
| JAK2/STAT3信号通路介导了甲基汞对小鼠星形胶质细胞神经元C8-D1A细胞系的毒性作用 |
Ahmed, A. |
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N/A |
JAK2/STAT3 signaling pathway mediates methylmercury toxicity in mouse astrocyte neuronal C8-D1A cell line |
| 皮质醇动态变化及斑马鱼幼体在反复应激下依赖于糖皮质激素受体（GR）的反馈调节 |
Castillo-Ramirez, L. A. |
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N/A |
Cortisol dynamics and GR-dependent feedback regulation in zebrafish larvae exposed to repeated stress |
| 早期生活挑战增强了斑马鱼幼体的皮质醇调节能力 |
Castillo-Ramirez, L. A. |
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N/A |
Early life challenge enhances cortisol regulation in zebrafish larvae |
| 自扩增与环状mRNA疫苗在SARS-CoV-2免疫原性与保护效力方面的比较 |
Singh, O. N. |
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N/A |
Comparison of immunogenicity and protection efficacy of self-amplifying and circular mRNA vaccines for SARS-CoV-2 |
| 肩胛间棕色脂肪组织的交感神经支配并不是雄性饮食诱导肥胖大鼠中OT引发体重增加和脂肪减少的主要介质。 |
Edwards, M. M. |
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N/A |
Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats |
| EFP分析器：一款快速、准确且易于教学的程序，用于分析由诱导多能干细胞衍生的心肌细胞产生的胞外场电位 |
Patel, N. P. |
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N/A |
EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes |
| 季节性到年代际叶面积动态的通用模型 |
Zhou, B. |
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N/A |
A general model for the seasonal to decadal dynamics of leaf area |
| 全球鉴定衣藻中AGO3-RNA相互作用揭示了小RNA介导的核与叶绿体基因表达调控 |
Murakami, S. |
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N/A |
Global identification of AGO3-RNA interactions in Chlamydomonas reveals the small RNA-mediated regulation of nuclear and chloroplast gene expression |
| 利用明场显微镜进行虚拟染色，实现植物细胞结构的无标记定量分析 |
Ichita, M. |
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N/A |
Virtual staining from bright-field microscopy for label-free quantitative analysis of plant cell structures |
| 两种物种和两种核型？西番莲属植物（Passifloraceae）中西番莲（Passiflora foetida L.）与西番莲（P. vesicaria L.）之间的细胞遗传分化 |
Zirpoli, B. |
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N/A |
Two species and two karyotypes? Cytogenetic differentiation between Passiflora foetida L. and P. vesicaria L. (Passifloraceae) |
| CRISPR敲除偏向冬季的SUT4基因改变了田间种植杂交杨树的物候、生物量积累和繁殖能力。 |
Tuma, T. T. |
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N/A |
CRISPR knockout of winter-biased SUT4 alters phenology, biomass accrual, and fertility of field-grown hybrid poplar |
| 苜蓿（Medicago truncatula）中的LYR4胞内域在免疫信号传导中充当支架，与其磷酸化活性无关。 |
Simonsen, B. |
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N/A |
The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity |
| 印度次喜马拉雅地区传统作物的生物文化脆弱性 |
Jaggi, H. |
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N/A |
Biocultural vulnerability of traditional crops in the Indian Trans Himalaya |
| 生长素-水杨酸跷跷板调节植物生长与食草动物防御之间的年龄依赖性平衡 |
Han, W.-H. |
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N/A |
Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense |
| 在马达加斯加的自然短日照和低肥力条件下，qHd7.1数量性状位点上的DJ123等位基因促进了早熟，且不影响产量。 |
Kondo, K. |
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N/A |
A DJ123 allele at the heading date quantitative trait locus qHd7.1 promotes early heading without yield penalties under natural short-day and low fertility conditions in Madagascar |
| 水力机械信号的统一框架：植物信号是否随流而动？ |
Bacheva, V. |
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N/A |
A unified framework for hydromechanical signaling: Do plant signals go with the flow? |
| 使用单色X射线荧光分析法对植物组织中的定量轻元素（钠和钾）进行分析 |
Kahlon, P. S. |
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N/A |
Quantitative light element (sodium and potassium) profiling in plant tissues using monochromatic X-ray fluorescence analysis |
| 核孔复合体在植物中充当pri-miRNA转录和加工的枢纽 |
Gonzalo, L. |
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N/A |
The Nuclear Pore Complex acts as a hub for pri-miRNA transcription and processing in plants |
| 可溶性CD52免疫抑制的分子基础由N-连接和O-连接糖基与HMGB1 Box B的相互作用所定义。 |
DeBono, N. J. |
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N/A |
The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 Box B |
| 基底隧道调节透明质酸合酶中的底物特异性转换 |
Zhu, K. |
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N/A |
Substrate tunnel regulates substrate specificity switching in hyaluronan synthase |
| CRB2耗竭诱导YAP信号传导并破坏足细胞的机械感应 |
Sun, Y. |
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N/A |
CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes |
| Shaker钾离子通道电压门控及达伐吡啶结合的结构基础：闭合状态模型揭示 |
Pinto-Anwandter, B. I. |
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N/A |
Structural Basis for Voltage Gating and Dalfampridine Binding in the Shaker Potassium Channel Revealed by Closed-State Model |
| 同步辐射扫描化石的自动分割 |
During, M. A. D. |
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N/A |
Automated segmentation of synchrotron-scanned fossils |
| 大麦可能是根寄生杂草列当的潜在陷阱作物。 |
Inoue, M. |
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N/A |
Barley is a potential trap crop for root parasitic weeds broomrapes |
| 根系重塑机制与耐盐权衡：HKT1、TMAC2和TIP2;2在拟南芥中的作用 |
Alshareef, N. |
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N/A |
Root Remodeling Mechanisms and Salt Tolerance Trade-Offs: The Roles of HKT1, TMAC2, and TIP2;2 in Arabidopsis |
| 人抗体识别的流感H1和H3血凝素上的保守位点 |
Maurer, D. P. |
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N/A |
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies |
| 拓扑异构酶1活性的表观遗传调控揭示了癌症的脆弱性 |
Lee, T. |
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N/A |
Epigenetic control of Topoisomerase 1 activity presents a cancer vulnerability |
| 实验生物化学家和其他分子科学家机器学习入门 |
Vince, M. J. |
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N/A |
Getting Started with Machine Learning for Experimental Biochemists and Other Molecular Scientists |
| 使用天然质谱技术通过丙氨酸扫描定义膜蛋白-脂质相互作用位点 |
Jayasekera, H. S. |
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N/A |
Alanine Scanning to Define Membrane Protein-Lipid Interaction Sites Using Native Mass Spectrometry |
| 通过激光诱导的Soret效应实现亚稳态相分离液滴生成及长时间DNA富集 |
Kobayashi, M. |
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N/A |
Metastable phase-separated droplet generation and long-time DNA enrichment by laser-induced Soret effect |
| 一个用于罕见癌症靶点发现的框架 |
Li, B. |
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N/A |
A framework for target discovery in rare cancers |
| 姜黄素和胡椒碱纳米颗粒调节前列腺癌中的类固醇生物合成 |
Yakubu, J. |
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N/A |
Nanoparticles with Curcumin and Piperine Modulate Steroid Biosynthesis in Prostate Cancer |
| 杜氏栀子（Gardenia duerrii）（Gardenieae科：茜草科），一种来自印度的新物种，以及Gardenia resinifera Roth的重新定型 |
K, R. K. |
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N/A |
Gardenia duerrii (Gardenieae : Rubiaceae), a new species from India and Neotypification of Gardenia resinifera Roth |
| 默认模式网络中经验的碎片化和多线程处理 |
Yazin, F. |
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N/A |
Fragmentation and Multithreading of Experience in the Default-Mode Network |
| 在健康泰国人群中，通过威斯康星卡片分类测试测量的认知变异性的蛋白质组关联：一种机器学习方法 |
Chen, C. |
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N/A |
Proteomic associations with cognitive variability as measured by the Wisconsin Card Sorting Test in a healthy Thai population: A machine learning approach |
| 将宿主状况预测因子整合到病毒排放的时空多尺度模型中 |
Kramer, A. M. |
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N/A |
Integrating predictors of host condition into spatiotemporal multi-scale models of virus shedding |
| 致癌性改变、种族与接受体细胞肿瘤下一代测序的美国转移性前列腺癌退伍军人生存率的关系 |
Valle, L. F. |
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N/A |
Oncogenic Alterations, Race, and Survival in US Veterans with Metastatic Prostate Cancer Undergoing Somatic Tumor Next Generation Sequencing |
| 生物医学数据的AI准备度：Bridge2AI建议 |
Clark, T. |
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N/A |
AI-readiness for Biomedical Data: Bridge2AI Recommendations |
| 降低ETFDH表达可优化癌细胞的生物能量学 |
Papadopoli, D. |
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N/A |
Reduction in ETFDH expression optimizes cancer cell bioenergetics |
| 一种自适应自回归扩散方法用于设计主动人源化抗体和纳米抗体 |
Ma, J. |
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N/A |
An adaptive autoregressive diffusion approach to design active humanized antibody and nanobody |
| 高效推理、训练与微调蛋白质语言模型 |
Celik, M. H. |
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N/A |
Efficient Inference, Training, and Fine-tuning of Protein Language Models |
| 在癌症单细胞研究中，通过筛选去除高线粒体含量的细胞，可以有效清除那些代谢发生改变的恶性细胞群体，这些细胞群体在生物学上仍然具有活力。 |
Yates, J. |
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N/A |
Filtering cells with high mitochondrial content removes viable metabolically altered malignant cell populations in cancer single-cell studies |
| scMoE：用于从异质性单细胞RNA测序数据中学习层次化、细胞类型特异性和可解释表示的单细胞专家混合模型 |
Huang, M. |
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N/A |
scMoE: single-cell mixture of experts for learning hierarchical, cell-type-specific, and interpretable representations from heterogeneous scRNA-seq data |
| 致癌长链非编码RNA NEAT1和MALAT1在二维单层与三维肿瘤球体培养中的差异表达及其对癌症进展的意义 |
Ghosh, A. |
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N/A |
Differential expression of oncogenic lncRNAs NEAT1 and MALAT1 in 2D monolayer vs. 3D tumoroid culture and its implications in cancer progression |
| Unc-51样激酶1（ULK1）调控细菌泛素化和p62招募在李斯特菌异噬清除过程中的作用 |
Siqueira, M. S. |
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N/A |
Unc-51-like Kinase 1 (ULK1) Regulates Bacterial Ubiquitylation and p62 Recruitment during Xenophagic Clearance of Listeria monocytogenes |
| 甘蓝型油菜高温萌发适应性的未开发多样性 |
Tiret, M. |
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N/A |
An unexplored diversity for adaptation of germination to high temperatures in Brassica species |
| 来自热河生物群的具冠白垩纪反鸟类中的虹彩结构色 |
LI, Z. |
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N/A |
Iridescent structural coloration in a crested Cretaceous enantiornithine bird from Jehol Biota |
| 组装钌复合物形成钌体，释放铁蛋白吞噬介导的肿瘤抑制作用 |
Meng, C. |
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N/A |
Assembling Ruthenium Complexes to Form Ruthenosome Unleashing Ferritinophagy-mediated Tumor Suppression |
| 半胱氨酸氧化对SARS-CoV-2刺突蛋白构象变化的影响：来自原子模拟的见解 |
Ghasemitarei, M. |
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N/A |
Effect of cysteine oxidation in SARS-CoV-2 Spike protein on its conformational changes: insights from atomistic simulations |
| 血管生成和免疫预测因素在伴有静脉瘤栓的肾细胞癌中对新辅助阿昔替尼反应的影响 |
Wray, R. |
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N/A |
Angiogenic and Immune Predictors of Neoadjuvant Axitinib Response in Renal Cell Carcinoma with Venous Tumour Thrombus |
| 染色体不稳定性通过细胞外囊泡中的EFEMP1促进细胞迁移和侵袭 |
Foijer, F. |
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N/A |
Chromosomal instability promotes cell migration and invasion via EFEMP1 in extracellular vesicles |
| 脂联素受体激动剂可预防杜氏肌营养不良小鼠模型中的右心室组织病理学变化。 |
Gandhi, S. |
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N/A |
Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy |
| TIR信号激活了细菌中的类似胱天蛋白酶的免疫反应。 |
ROUSSET, F. |
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N/A |
TIR signaling activates caspase-like immunity in bacteria |
| 一项新的筛选检测揭示，氨基糖苷类抗生素干扰Tau/MDM2相互作用。 |
Sola, M. |
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N/A |
A new screening assay reveals that aminoglycoside antibiotics interfere with the Tau/MDM2 interaction |
| 将IICR扩展到复杂的非平稳结构化模型 |
Jouniaux, A. |
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N/A |
Extending the IICR to complex non-stationary structured models |
| 从geissoschizine出发的单萜吲哚生物碱的分歧生物合成 |
Kamileen, M. O. |
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N/A |
Divergent biosynthesis of monoterpene indole alkaloids from geissoschizine |
| 替代性转录本通过重新编码人类基因，表达出重叠且发生移码的微型蛋白质。 |
Su, H. |
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N/A |
Alternative transcripts recode human genes to express overlapping, frameshifted microproteins |
| 黄芩素通过下调新生儿Fc受体并通过NF-κB信号通路改善实验性溃疡性结肠炎的复发 |
Hu, H. |
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N/A |
Baicalein ameliorates experimental ulcerative colitis recurrency by downregulating neonatal Fc receptor via the NF-κB signaling pathway |
| 从等位基因包含中学习抗体序列约束 |
Jagota, M. |
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N/A |
Learning antibody sequence constraints from allelic inclusion |
| 纽芬兰与拉布拉多鳕鱼崩溃后的快速生态系统变化 |
Wudrick, A. |
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N/A |
Rapid ecosystem change after the cod collapse in Newfoundland & Labrador |
| 何时信任表观遗传时钟：避免衰老干预中的假阳性。 |
Borrus, D. S. |
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N/A |
When to Trust Epigenetic Clocks: Avoiding False Positives in Aging Interventions. |
| 对Batrachochytrium dendrobatidis GPL JEL423的近乎完整的端粒到端粒基因组组装揭示了CBM18基因家族的扩展和M36金属蛋白酶基因家族的收缩。 |
Helmstetter, N. |
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N/A |
A near-complete telomere-to-telomere genome assembly for Batrachochytrium dendrobatidis GPL JEL423 reveals a CBM18 gene family expansion and a M36 metalloprotease gene family contraction. |
| 可转座元件小RNA和长RNA在老化大脑中的作用及其对亨廷顿病和帕金森病的启示 |
Dayama, G. |
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N/A |
Transposable element small and long RNAs in aging brains and implications in Huntington's and Parkinson's disease |
| 全基因组变异分析揭示了埃及伊蚊及其形态变种埃及伊蚊var. luciensis之间不同的遗传特征。 |
Gupta, B. |
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N/A |
Genome-wide variant analysis reveals divergent genetic signatures in Aedes aegypti and its morphological variant Aedes aegypti var. luciensis |
| WRI1在天然橡胶中多乳汁代谢途径整合调控中的普遍功能 |
Fan, R. |
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N/A |
Universal function of WRI1 involved in integrated regulation of multiple latex metabolism pathways in Natural Rubber |
| 在黑色素瘤起始过程中，吸引子状态区域先于神经嵴命运出现。 |
McConnell, A. M. |
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N/A |
An attractor state zone precedes neural crest fate in melanoma initiation |
| 线粒体靶向质体醌疗法改善了小鼠卵巢癌恶病质前期的早期肌肉无力症状 |
Delfinis, L. J. |
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N/A |
Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice |
| CXADR是一种人IgG Fc受体。 |
Emig, C. J. |
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N/A |
CXADR is a Human IgG Fc Receptor |
| 不同的母胎免疫特征描绘了尿路感染后早产的发作 |
Ottinger, S. |
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N/A |
Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection |
| 在人类慢性基孔肯雅病毒性关节炎疾病中鉴定免疫原性和交叉反应的基孔肯雅病毒特异性CD4+ T细胞表位 |
Agarwal, R. |
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N/A |
Identification of immunogenic and cross-reactive chikungunya virus-specific CD4+ T cell epitopes in chronic chikungunya viral arthritic disease in humans |
| 小鼠接种高效和低效全细胞百日咳疫苗后产生的抗体谱 |
Adewunmi, Y. |
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N/A |
Antibody Profiles Elicited by Potent and Subpotent Whole Cell Pertussis Vaccines in Mice |
| 2,3,7,8-四氯二苯并-对-二噁英（TCDD）引发了与肝脏芳香烃受体（AHR）介导的差异基因表达相关的剂量依赖性小鼠尿液代谢组变化。 |
Sink, W. J. |
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N/A |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) elicited dose-dependent shifts in the murine urinary metabolome associated with hepatic AHR-mediated differential gene expression |
| 无花果蜂的基因组揭示了无花果-无花果蜂共生关系中的适应与共进化 |
Lo, B.-W. |
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N/A |
Genomes of Wiebesia fig wasps reveal the adaptation and codiversification in fig-fig wasp mutualism |
| 通过空间脂质组学和蛋白质组学相关性进行异质性评估和蛋白质通路预测：推进用于人类胶质母细胞瘤预后的干蛋白质组学概念 |
Lagache, L. |
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N/A |
Heterogeneity Assessment and Protein Pathway Prediction via Spatial Lipidomic and Proteomic Correlation: Advancing Dry Proteomics concept for Human Glioblastoma Prognosis |
| AMPK激活通过其去磷酸化促进TFEB的转录激活。 |
Negoita, F. |
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N/A |
AMPK activation promotes transcriptional activation of TFEB through its dephosphorylation |
| 利用β-孔形成毒素Aerolysin增强单链纳米体对Notch的抑制及亲和力 |
Lemmex, A. |
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N/A |
Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin |
| 利用时序卷积生成语言模型设计功能性酵母启动子序列 |
Alsaggaf, I. |
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N/A |
Functional yeast promoter sequence design using temporal convolutional generative language models |
| 部分特征化的拓扑结构指导可靠的无锚点单细胞RNA整合 |
He, C. |
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N/A |
Partially characterized topology guides reliable anchor-free scRNA integration |
| 膜联蛋白A6通过与三阴性乳腺癌细胞中的SNAP23相互作用，调节促炎细胞因子和外泌体的分泌。 |
Sakwe, N. I. |
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N/A |
Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells |
| 钴原卟啉IX对小鼠粒细胞动员和代谢标志物的剂量和时间依赖性效应 |
Bednarz, A. |
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N/A |
Dose- and time-dependent effects of cobalt protoporphyrin IX on granulocyte mobilization and metabolic markers in mice |
| 转录组分析揭示了幼年公牛鳟鱼亚致死热应激阈值的见解 |
Best, C. |
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N/A |
Transcriptional profiling provides insights on sublethal thermal stress thresholds in juvenile bull trout |
| 线粒体靶向抗氧化剂SkQ1可预防与线粒体相关的细胞凋亡，但不能预防坏死性凋亡或卵巢癌中的骨骼肌萎缩。 |
Khajehzadehshoushtar, S. |
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N/A |
The mitochondrial-targeted antioxidant SkQ1 prevents mitochondrial-linked apoptosis but not necroptosis or skeletal muscle atrophy in ovarian cancer |
| 利用iColonEpithelium代谢重建理解人类结肠上皮细胞中与疾病相关的代谢变化 |
Jiang, B. |
PDF |
N/A |
Understanding disease-associated metabolic changes in human colon epithelial cells using iColonEpithelium metabolic reconstruction |
| 成虫饮食对昆虫Narnia femorata（半翅目：Coreidae科）的角质层厚度和抗损伤能力有显著影响。 |
Greenway, E. V. |
PDF |
N/A |
Adult diet strongly affects cuticle thickness and its injury resistance in the insect Narnia femorata (Hemiptera: Coreidae) |
| 用于研究基因组组织与转录调控相互作用的计算机纳米显微镜 |
Gopi, S. |
PDF |
N/A |
In silico nanoscope to study the interplay of genome organization and transcription regulation |
| 人类世鱼类食物网的退化 |
Carvajal-Quintero, J. D. |
PDF |
N/A |
Degradation of fish food webs in the anthropocene |
| 合作最大化生物多样性 |
Godoy, O. |
PDF |
N/A |
Cooperation maximizes biodiversity |
| 开发和验证用于eDNA监测和认证10种商业上重要的秘鲁海洋物种的多功能种特异性引物检测方法 |
Marin, A. |
PDF |
N/A |
Development and validation of versatile species-specific primer assays for eDNA monitoring and authentication of 10 commercially important Peruvian marine species |
| 通过遗传免疫表型分析，探索冈比亚按蚊免疫细胞生物学的新维度 |
Samantsidis, G.-R. |
PDF |
N/A |
Exploring new dimensions of immune cell biology in Anopheles gambiae through genetic immunophenotyping |
| 子宫内膜在着床窗口期细胞成分的变化与复发性流产相关。 |
Reddin, I. G. |
PDF |
N/A |
Changes in the cellular composition of the endometrium during the implantation window are associated with recurrent pregnancy loss |
| 蕨类植物满江红（Azolla caroliniana）的基因组组装 |
Song, M. J. |
PDF |
N/A |
The genome assembly of the duckweed fern, Azolla caroliniana |
| gp82结合的原子级洞察：对克鲁斯锥虫宿主细胞入侵的微秒级、百万原子探索 |
Rosa, R. S. L. |
PDF |
N/A |
Atomistic Insights into gp82 Binding: A Microsecond, Million-Atom Exploration of Trypanosoma cruzi Host-Cell Invasion |
| 铜绿假单胞菌H16中利用H2生产木糖醇 |
Jämsä, T. |
PDF |
N/A |
H2-driven xylitol production in Cupriavidus necator H16 |
| 解析蛋白质-碳水化合物界面的多样性：来自多尺度研究的见解 |
Gheeraert, A. |
PDF |
N/A |
Unraveling the diversity of protein-carbohydrate interfaces: insights from a multi-scale study |
| 通过自动化计算流程HitList发现重要人畜和植物真菌病原体的新靶点 |
Condon, D. E. |
PDF |
N/A |
Discovery of Novel Targets for Important Human and Plant Fungal Pathogens via Automated Computational Pipeline HitList |
| 通过碱基对基序能量进行RNA二级结构的深度可泛化预测 |
Zhu, H. |
PDF |
N/A |
Deep generalizable prediction of RNA secondary structure via base pair motif energy |
| 长读长比对堆积的K-mer分析用于结构变异基因分型 |
ENGLISH, A. C. |
PDF |
N/A |
K-mer analysis of long-read alignment pileups for structural variant genotyping |
| Metagenomics-Toolkit：灵活高效的云端宏基因组学工作流程，具备机器学习驱动的资源分配功能 |
Belmann, P. |
PDF |
N/A |
Metagenomics-Toolkit: The Flexible and Efficient Cloud-Based Metagenomics Workflow featuring Machine Learning-Enabled Resource Allocation |
| 单个癌细胞中多种ecDNA类型的维持 |
Scanu, E. |
PDF |
N/A |
The maintenance of multiple ecDNA types in single cancer cells |
| 利用ReSisTrace谱系追踪技术揭示急性髓系白血病中FLT3抑制剂的预敏化剂 |
Eriksson, J. |
PDF |
N/A |
Uncovering pre-sensitizing agents to FLT3 inhibitors in acute myeloid leukemia with ReSisTrace lineage tracing |
| 单链DNA结合因子SUB1/PC4减轻端粒处的复制应激，是ALT癌细胞的脆弱点 |
Dubois, J.-C. |
PDF |
N/A |
The Single-Stranded DNA-Binding Factor SUB1/PC4 Alleviates Replication Stress at Telomeres and is a Vulnerability of ALT Cancer Cells |
| IRE1依赖的GOLIM4表达控制蛋白质分泌以调节胶质母细胞瘤细胞的粘附和迁移 |
Bakambamba, K. |
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N/A |
IRE1-dependent GOLIM4 expression controls protein secretion to modulate glioblastoma cell adhesion and migration |
| 综合结构-功能分析揭示了影响致癌KRAS活性的获得性和丧失性功能机制 |
Kwon, J. |
PDF |
N/A |
Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity |
| 染色体外DNA驱动胶质母细胞瘤中的癌基因空间异质性与演化 |
Noorani, I. |
PDF |
N/A |
Extrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastoma |
| 抑制调节性T细胞中的UBE2N可增强抗癌免疫力 |
Miao, W. |
PDF |
N/A |
Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer |
| 贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。 |
Georgiadou, A. |
PDF |
N/A |
Anemia and tissue hypoxia are major determinants of malarial hypelactatemia |
| 长链酰基辅酶A脱氢酶的丧失可预防急性肾损伤 |
Chiba, T. |
PDF |
N/A |
Loss of long-chain acyl-CoA dehydrogenase protects against acute kidney injury |
| 由羟基醌形成驱动的CBD毒性 |
Montero, M. I. |
PDF |
N/A |
Cannabidiol Toxicity Driven by Hydroxyquinone Formation |
| 新型链霉菌SCA4-21对香蕉枯萎病的生物防治效果及机制 |
Qi, D. |
PDF |
N/A |
Biocontrol efficiency and mechanism of novel Streptomyces luomodiensis SCA4-21 against banana Fusarium wilt |
| SLB-msSIM：一种基于光谱库的多重分段SIM平台，用于单细胞蛋白质组学分析 |
Senavirathna, L. |
PDF |
N/A |
SLB-msSIM: a spectral library-based multiplex segmented SIM platform for single-cell proteomic analysis |
| 机械感受器在响应微生物感染时启动先天免疫 |
Stucchi, G. |
PDF |
N/A |
Mechanoreceptors initiate innate immunity in response to microbial infections |
| 生成人类诱导多能干细胞（iPSC）衍生的胰腺类器官，以研究胰腺发育和疾病 |
Darrigrand, J.-F. |
PDF |
N/A |
Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease |
| 无特质匹配：使用对应分析分析交互网络的潜在结构 |
Nicvert, L. |
PDF |
N/A |
Trait matching without traits: using correspondence analysis to analyze the latent structure of interaction networks |
| 土地利用强度、生产力和地上丰富度对温带草地种子雨的影响 |
Klinger, Y. P. |
PDF |
N/A |
Impact of land-use intensity, productivity, and aboveground richness on seed rain in temperate grasslands |
| 长链非编码RNA NEAT1和MALAT1的系统发育研究：推断结构-功能联系 |
Arkhipova, K. |
PDF |
N/A |
Phylogenetic Study of Long Non-Coding RNA NEAT1 and MALAT1 to Infer Structural-Functional Connection |
| 入侵植物马缨丹（Lantana camara）的种群结构受其交配系统的影响。 |
Praveen, P. |
PDF |
N/A |
The population structure of invasive Lantana camara is shaped by its mating system |
| PWWP-ADD和DNMT3B1的N端结构域赋予了对发育调控的CpG岛甲基化的特异性 |
Yasmin, K. |
PDF |
N/A |
PWWP-ADD and N-terminal domains of DNMT3B1 confer specificity for developmentally regulated CpG island methylation |
| 有机光电纳米生物界面实现了多尺度生物调控 |
Mueller, C. |
PDF |
N/A |
Organic opto-nanobiointerface enables multiscale biomodulation |
| 等分散泊松分布（Equi-Under-Dispersed Possion Distribution，简称EUPoisson） |
Hassan, M. |
PDF |
N/A |
Equi-Under-Dispersed Possion Distribution (EUPoisson) |
| 智能数据工厂：面向主动学习驱动分子数据采集的志愿者计算平台 |
Ghukasyan, T. |
PDF |
N/A |
SMART DATA FACTORY: VOLUNTEER COMPUTING PLATFORM FOR ACTIVE LEARNING-DRIVEN MOLECULAR DATA ACQUISITION |
| 一种高吞吐量的单分子平台，用于研究DNA超螺旋效应对蛋白质-DNA相互作用的影响 |
Lee, H. |
PDF |
N/A |
A high throughput single molecule platform to study DNA supercoiling effect on protein-DNA interactions |
| 单核分析未折叠蛋白反应（SNUPR）：揭示多发性骨髓瘤中硼替佐米耐药机制的新方法 |
Arguello, R. J. |
PDF |
N/A |
Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma |
| 使用区间分析设计满足稳态规格的生物分子电路参数区间 |
Prakash, R. |
PDF |
N/A |
Design of Parameter Intervals to Meet Steady-State Specifications in Biomolecular Circuits using Interval Analysis |
| 洗牌：扩展合成生物学工具包以用于类似洗牌子的重组系统 |
Katalinic, J. |
PDF |
N/A |
Do the shuffle: Expanding the synthetic biology toolkit for shufflon-like recombination systems |
| 多细胞比例-积分-微分控制对生物过程的鲁棒调节 |
Martinelli, V. |
PDF |
N/A |
Multicellular Proportional-Integral-Derivative Control for Robust Regulation of Biological Processes |
| 太暗、太亮和刚刚好：适应光应激和限制下的莱茵衣藻昼夜节律程序的系统分析 |
Dupuis, S. |
PDF |
N/A |
Too dim, too bright, and just right: Systems analysis of the Chlamydomonas diurnal program upon acclimation to light stress and limitation |
| 鞭毛运动和黏液环境影响铜绿假单胞菌在慢性肺部感染中的聚集介导的抗生素耐药性 |
Higgs, M. G. |
PDF |
N/A |
Flagellar motility and the mucus environment influence aggregation mediated antibiotic tolerance of Pseudomonas aeruginosa in chronic lung infection |
| 利用分子生物学和微生物学相结合的方法，鉴定英国蚕豆根腐病相关的镰刀菌种类 |
Attar, B. |
PDF |
N/A |
Identifying the Fusarium species involved in foot rot disease of faba beans in the UK using a combined molecular and microbiological approach |
| 基于营养的根际微生物群工程原理，通过活体微生物接种剂调控作物产量 |
Huang, Y. |
PDF |
N/A |
Principles of nutrition-dependent root-microbiome engineering for regulating crop yield via live microbial inoculants |
| 抑制白假丝酵母毒力因子由维罗纳气单胞菌V03衍生的环二肽实现 |
Sekar, J. |
PDF |
N/A |
Inhibition of Candida albicans virulence factor by cyclic dipeptides derived from Aeromonas veronii V03 |
| 增强抗菌药物耐药性监测：基于牛津纳米孔测序技术（ONT）的核心质粒多位点序列分型（cpMLST） |
Xavier, B. B. |
PDF |
N/A |
Enhancing antimicrobial resistance monitoring: Core Plasmid Multi-Locus sequence typing (cpMLST) with Oxford Nanopore sequencing technology (ONT) |
| 理解结核分枝杆菌的流行病学和发病机制，结合非冗余泛基因组和群体遗传学 |
Zhou, Y. |
PDF |
N/A |
Understanding the epidemiology and pathogenesis of Mycobacterium tuberculosis with non-redundant pangenome and population genetics |
| 碳青霉烯耐药肺炎克雷伯菌的临床特征、耐药基因及毒力分析 |
He, J. |
PDF |
N/A |
Clinical characteristics, drug-resistance genes and virulence analysis of carbapenem-resistant Klebsiella pneumoniae |
| 基于RNA toehold开关的报告分析法用于评估细菌对反义寡核苷酸的摄取 |
Sarkar, P. |
PDF |
N/A |
RNA toehold switch-based reporter assay to assess bacterial uptake of antisense oligomers |
| 关键刺突蛋白突变的流行及其对孟加拉国锡尔赫特市COVID-19临床表现影响有限 |
Akter, S. |
PDF |
N/A |
Prevalence of Key Spike Protein Mutations and Their Limited Effect on COVID-19 Clinical Manifestations in Sylhet, Bangladesh |
| 长期免疫效果：经伽马射线照射的SARS-CoV-2 S1蛋白亚单位疫苗微针阵列贴片在小鼠中的研究 |
Kim, E. |
PDF |
N/A |
Long-term Immunity of a Microneedle Array Patch of SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice |
| FBXW7通过减轻c-MYC对丙酮酸羧化酶的抑制作用，支持代谢灵活性。 |
Lisci, M. |
PDF |
N/A |
FBXW7 alleviates c-MYC repression of pyruvate carboxylase to support metabolic flexibility |
| 探究DNA损伤位点揭示了依赖于上下文和新的DNA损伤反应因子 |
Cardoso da Silva, R. |
PDF |
N/A |
Probing DNA damage sites reveals context-dependent and novel DNA damage response factors |
| 依赖于序列的跨膜转运蛋白介导的膜界面螺旋插入的尺度 |
Grau, B. |
PDF |
N/A |
Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes |
| 抑制衰老的载脂蛋白E4小鼠体内的胆固醇储存酶ACAT1/SOAT1，改变了它们大脑的炎症特征。 |
Huynh, T. N. |
PDF |
N/A |
Inhibiting the cholesterol storage enzyme ACAT1/SOAT1 in aging Apolipoprotein E4 mice alter their brains inflammatory profiles |
| 水热处理酵母细胞壁在单独条件下抑制MCF7细胞的生长。 |
KITAGAWA, T. |
PDF |
N/A |
Hydrothermally treated yeast cell wall suppresses the growth of MCF7 cells under isolated conditions. |
| 进化尺度酶学使我们能够在多峰催化景观中预测生化常数 |
Muir, D. F. |
PDF |
N/A |
Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape |
| 利用数据不平衡性来增强化合物-蛋白质相互作用预测模型 |
Lin, W. |
PDF |
N/A |
Utilizing data imbalance to enhance compound-protein interaction prediction models |
| 离子迁移谱引导的分子鉴别：脂质组学实验中区分缩醛磷脂与其他醚脂的方法 |
Koch, J. |
PDF |
N/A |
Trapped ion mobility spectrometry-guided molecular discrimination between plasmalogens and other ether lipids in lipidomics experiments |
| 唾液代谢组分的构成与SARS-CoV2感染及COVID-19疾病的严重程度显著相关。 |
Larios-Serrato, V. |
PDF |
N/A |
Composition of saliva metabolome is significantly associated with SARS-CoV2 infection and with severity of COVID-19 disease |
| 使用合成RNA评估直接RNA测序中的多腺苷酸尾长度推断。 |
Chang, J. J.-Y. |
PDF |
N/A |
Using synthetic RNA to benchmark poly(A) length inference from direct RNA sequencing. |
| 孟加拉国禽类样本中分离出的细菌中的重金属与抗生素共耐药性：一种新兴的环境威胁 |
Sarker, A. |
PDF |
N/A |
Heavy Metal and Antibiotic Co-resistance in Bacteria Isolated from Poultry Samples in Bangladesh: An Emerging Environmental Threat |
| 肺和肠道微生物群对SARS-CoV-2感染的不同反应：武汉株与Omicron株在K18-hACE2转基因小鼠中的比较研究 |
Kim, C. W. |
PDF |
N/A |
Differential Responses of Lung and Intestinal Microbiota to SARS-CoV-2 Infection: A Comparative Study of the Wuhan and Omicron Strains in K18-hACE2 tg Mice |
| 大麦miRNAs及其靶标在发育早期对热胁迫的响应调控 |
Kruszka, K. |
PDF |
N/A |
Barley miRNAs and their targets regulation in response to heat stress at the early stage of development |
| 综合系统生物学研究表明，线粒体功能和代谢的紊乱是导致保留射血分数的心力衰竭（HFpEF）的关键因素。 |
Gibb, A. A. |
PDF |
N/A |
Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF) |
| HT SpaceM：一种高通量且可重复的小分子单细胞代谢组学方法 |
Delafiori, J. |
PDF |
N/A |
HT SpaceM: A High-Throughput and Reproducible Method for Small-Molecule Single-Cell Metabolomics |
| β-淀粉样蛋白损害蛋白酶体结构和功能。蛋白酶体激活可减轻淀粉样蛋白引起的毒性和认知缺陷。 |
Davidson, K. |
PDF |
N/A |
β-Amyloid impairs Proteasome structure and function. Proteasome activation mitigates amyloid induced toxicity and cognitive deficits |
| 使用多重竞争性等位基因特异性PCR（mxKASP）基因分型确定合子性 |
de Visser, M. C. |
PDF |
N/A |
Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping |
| 在碱基切除修复途径的下游步骤中，LIG1和LIG3α在8-oxoG旁路过程中对polβ错配插入产物进行诱变连接 |
Lee, K. M. |
PDF |
N/A |
Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway |
| 对倍半萜香豆素合酶反应机制的预测表明其与三萜生物合成存在直接的进化联系。 |
Stephenson, M. J. |
PDF |
N/A |
Prediction of the reaction mechanisms of sesquiterpene coumarin synthases supports a direct evolutionary link with triterpene biosynthesis. |
| ProteinWeaver：一个用于可视化本体注释蛋白质网络的网络工具 |
Anderson, O. |
PDF |
N/A |
ProteinWeaver: A Webtool to Visualize Ontology-Annotated Protein Networks |
| 在感染沃尔巴克氏菌株wAlbB的埃及伊蚊孟加拉国品系中，适应性与登革病毒抑制的关系 |
Al-Amin, H. M. |
PDF |
N/A |
Fitness compatibility and dengue virus inhibition in a Bangladeshi strain of Aedes aegypti infected with the Wolbachia strain wAlbB |
| 以微外显子下游剪接供体位点为靶点的寡核苷酸：自闭症创新疗法 |
Martinez-Pizarro, A. |
PDF |
N/A |
OLIGONUCLEOTIDES TARGETING THE SPLICE ACCEPTOR SITE DOWNSTREAM OF A MICROEXON AS AN INNOVATIVE THERAPY FOR AUTISM |
| 实验田试验模型展示了气候危机将如何改变Vitis sp. L'Acadie Blanc叶片微环境和果实微环境的真菌群落。 |
Blakney, A. J. C. |
PDF |
N/A |
Experimental field trials model how the climate crisis will alter the phyllosphere and carposphere fungal communities of Vitis sp. L'Acadie Blanc |
| 贾第虫晚期ESCRT组分的不同功能：基于亚细胞分布和蛋白质相互作用的见解 |
Patra, N. |
PDF |
N/A |
Divergent Functions of Late ESCRT Components in Giardia lamblia: Insights from Subcellular Distributions and Protein Interactions |
| 象牙喙啄木鸟与蓝松鸦在频谱图层面的对比显示出差异 |
Williams, J. D. |
PDF |
N/A |
Ivory-billed Woodpecker and Blue Jay kent comparisons at spectrogram level reveal differences |
| 保守的基因内容和独特的系统发育历史特征了“bloopergene”，这是Triturus平衡致死系统的基础。 |
de Visser, M. C. |
PDF |
N/A |
Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system |
| 丝状真菌核基因组中的Zymocin样杀伤毒素基因簇 |
Heneghan, P. G. |
PDF |
N/A |
Zymocin-like killer toxin gene clusters in the nuclear genomes of filamentous fungi |
| 没有其微生物组的果蝇的实验进化 |
Malwade, A. |
PDF |
N/A |
Experimental evolution of Drosophila without its microbiome |
| 父系基因组消除、单基因复制和非典型性染色体系统的进化遗传学 |
Hitchcock, T. J. |
PDF |
N/A |
Paternal genome elimination, monogenic reproduction, and the evolutionary genetics of atypical sex chromosome systems |
| 信号调节结构如何演变：来自进化模型的见解 |
Asgari, D. |
PDF |
N/A |
How the Structure of Signaling Regulation Evolves: Insights from an Evolutionary Model |
| MIRAGE：一种结合变异功能信息的贝叶斯稀有变异关联分析方法 |
Han, S. |
PDF |
N/A |
MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants |
| Mettl5协调蛋白质的生成和PERIOD的降解，以调节果蝇的睡眠 |
Wu, X. |
PDF |
N/A |
Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila |
| NewtCap：一种高效的目标捕获方法，用于提升蝾螈科（真蝾螈和蝾螈）基因组研究 |
de Visser, M. C. |
PDF |
N/A |
NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts) |
| 一种用于纳米孔直接RNA测序中嵌合体伪影检测的基因组语言模型 |
Li, Y. |
PDF |
N/A |
A Genomic Language Model for Chimera Artifact Detection in Nanopore Direct RNA Sequencing |
| 从原始视频到行为分析：一种用于野外活动监测和行为识别的自动化流程 |
Silva, L. R. |
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N/A |
From raw footage to behaviour: an automated pipeline for activity monitoring and behaviour identification in the wild |
| 邻近标记揭示了人类线粒体导入受体蛋白TOMM20和TOMM70的不同相互作用伙伴 |
Akram, S. |
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N/A |
Proximity labeling reveals differential interaction partners of the human mitochondrial import receptor proteins TOMM20 and TOMM70 |
| 微尺度液滴中多能干细胞的培养可调节分化和组织模式化，使其趋向于芯片上的类器官 |
Vertti-Quintero, N. |
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N/A |
Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip |
| 用于选择性捕获和释放肝细胞来源的细胞外囊泡作为肝病生物标志物的磁点击捕获释放技术 |
Booijink, R. |
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N/A |
The Mag-Click-Capture-Release Technology for Selective Capture and Release of Hepatocyte-Derived Extracellular Vesicles as Biomarkers for Liver Disease |
| 单细胞转录组学揭示了硬皮病相关性肺动脉高压与特发性肺动脉高压在病理生物学上的差异，并为精准靶向治疗提供了机会。 |
Tuhy, T. |
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N/A |
Single-cell transcriptomics reveal diverging pathobiology and opportunities for precision targeting in scleroderma-associated versus idiopathic pulmonary arterial hypertension |
| LncRAnalyzer：揭示高粱基因组中的长非编码RNA并探索基因共表达模式 |
Nikhil, S. |
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N/A |
LncRAnalyzer: Uncovering Long Non-Coding RNAs and Exploring Gene Co-expression Patterns in Sorghum Genomics |
| μPIX：利用生成式人工智能实现增强、个性化和可持续的显微镜技术 |
Bon, G. |
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N/A |
μPIX: Leveraging Generative AI for Enhanced, Personalized and Sustainable Microscopy |
| 关于机器学习应用的蛋白质序列中注释的同源区域预处理 |
Malhis, N. |
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N/A |
Pre-processing annotated homologous regions in protein sequences concerning machine-learning applications |
| 改进的蛋白质相互作用模型预测了人类细胞系之间复合物的差异 |
Wilkins, G. R. |
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N/A |
Improved protein interaction models predict differences in complexes between human cell lines |
| 土壤有机质矿化的计算微生物学：利用曲线骨架概念划分计算机断层扫描图像中的三维孔隙空间 |
Belghali, Z. |
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N/A |
Computational microbiology of soil organic matter mineralization: Use of the concept of curve skeleton to partition the 3D pore space in computed tomography images |
| RSV基因组中的G四链体：潜在的抗病毒靶点。 |
Bose, D. |
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G-quadruplexes in the RSV genome: potential anti-viral targets. |
| 通过细胞周期实现核组织的三维记忆 |
Fujishiro, S. |
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N/A |
Three-dimensional memory of nuclear organization through cell cycles |
| AcMNPV核衣壳结构揭示了DNA通道组织及环状双链DNA杆状病毒的包装机制。 |
Effantin, G. |
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N/A |
Structure of AcMNPV nucleocapsid reveals DNA portal organization and packaging apparatus of circular dsDNA baculovirus. |
| 乳腺癌转移部位与单一营养水平无关 |
Abbott, K. L. |
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Site of breast cancer metastasis is independent of single nutrient levels |
| 通过纳米动力学变化在脂质膜中实现铁死亡的体内成像 |
Sonay, A. Y. |
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N/A |
In vivo imaging of ferroptosis through nanodynamic changes in lipid membranes |
| TFE3融合蛋白在转位性肾细胞癌中驱动氧化代谢、铁死亡抵抗和普遍的RNA合成。 |
Davidson, I. |
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TFE3 fusion proteins drive oxidative metabolism, ferroptosis resistance and general RNA synthesis in translocation renal cell carcinoma |
| 植物物种在花蜜过氧化氢含量上存在差异，这是一种某些细菌和酵母能够耐受的抗菌防御机制。 |
Landucci, L. |
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N/A |
Plant species vary in nectar peroxide, an antimicrobial defense tolerated by some bacteria and yeasts |
| 高通量生物多样性调查为最亮的昆虫类群带来了新的见解 |
Iwaszkiewicz-Eggebrecht, E. |
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N/A |
High-throughput biodiversity surveying sheds new light on the brightest of insect taxa |
| 小胶质细胞状态决定多发性硬化症中的病变动态 |
van den Bosch, A. M. |
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Microglial states determine lesion dynamics in multiple sclerosis |
| 内源性逆转录病毒样蛋白招募UBQLN2至应激颗粒，并改变其功能特性 |
Mohan, H. M. |
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Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties |
| 模拟微重力加速α-突触核蛋白聚集并诱导体外帕金森病模型中的氧化应激 |
Lentini, V. |
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Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model |
| 虚拟脑双胞胎的原理与操作 |
Hashemi, M. |
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Principles and Operation of Virtual Brain Twins |
| 在烟曲霉感染期间，IFN-STAT1-CYBB轴定义了保护性浆细胞样DC与中性粒细胞之间的交叉对话。 |
Guo, Y. |
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An IFN-STAT1-CYBB Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk During Aspergillus fumigatus Infection. |
| 心脏骤停小鼠模型中心肌炎症和转录组变化的时序动态 |
Panigrahi, S. |
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Temporal dynamics of inflammatory and transcriptome changes in the myocardium in a murine model of cardiac arrest |
| 在多发性硬化症中连接髓鞘与爱泼斯坦-巴尔病毒特异性免疫反应：综合公共T细胞受体库的见解 |
Valkiers, S. |
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N/A |
Linking myelin and Epstein-Barr virus specific immune responses in multiple sclerosis: insights from integrated public T cell receptor repertoires |
| 建立绿色藻类Chlamydomonas incerta作为重组蛋白生产的平台 |
Kang, K. |
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Establishing the green algae Chlamydomonas incerta as a platform for recombinant protein production |
| 一种Ⅰ型3' UTR衍生的sRNA参与了金黄色葡萄球菌中的血红素代谢和毒力 |
Silard, C. |
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A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus |
| Syntaxin11缺乏抑制CRAC通道的启动，从而抑制FHLH4患者T淋巴细胞的细胞毒性和基因表达。 |
Vig, M. |
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Syntaxin11 Deficiency Inhibits CRAC Channel Priming To Suppress Cytotoxicity And Gene Expression In FHLH4 Patient T Lymphocytes. |
| 改进的小鼠骨髓损伤模型中通过膜内骨化研究产后骨生成的方法 |
Stetsiv, M. |
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Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model |
| 棕榈酰化的输入蛋白α通过与NuMA的相互作用调节有丝分裂纺锤体的定向 |
Sutton, P. J. |
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Palmitoylated Importin α Regulates Mitotic Spindle Orientation Through Interaction with NuMA |
| 通过冷冻扫描透射电子断层成像技术捕捉到的线粒体分裂瞬间的影像 |
Kirchweger, P. |
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Snapshots of Mitochondrial Fission Imaged by Cryo-Scanning Transmission Electron Tomography |
| G-四链体配体RHPS4通过阻断电离辐射诱导的线粒体质量和活性的增加，破坏了细胞的放射抗性。 |
Tricot, S. |
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G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation. |
| 鞘脂类失衡加剧纤维状Tau诱导的内质膜硬化和破裂 |
Tittelmeier, J. |
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Sphingolipid imbalance aggravates fibrillar Tau-induced endomembrane rigidification and rupture |
| E3泛素连接酶Trip12在造血干细胞发育过程中减弱Wnt9a/Fzd9b信号传导 |
Ensing, J. |
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The E3 Ubiquitin Ligase Trip12 attenuates Wnt9a/Fzd9b signaling during hematopoietic stem cell development |
| PUF RNA结合蛋白FBF-2在不结合RNA的情况下维持干细胞状态。 |
Carrick, B. H. |
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The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA |
| 小鼠胚胎在失去与子痫前期相关的丝氨酸蛋白酶前列腺素后红细胞成熟受损 |
Di Carlo, S. |
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N/A |
Impaired erythroid maturation in murine embryos upon loss of the preeclampsia-associated serine protease prostasin |
| 土壤微生物影响植物可塑性的生态和进化 |
Bolin, L. G. |
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N/A |
Soil microbes influence the ecology and evolution of plant plasticity |
| 基因和系统基因组的不一致揭示了温带Loliinae草本植物中的冲突杂交事件 |
Moreno-Aguilar, M. F. |
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Genic and phylogenomic discordances reveal conflicting hybridization episodes in temperate Loliinae grasses |
| 欧洲小麦白粉病的群体基因组学与分子流行病学研究 |
Jigisha, J. |
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N/A |
Population genomics and molecular epidemiology of wheat powdery mildew in Europe |
| 酵母细胞裂解突变体cly8是ESP1的一个温度敏感等位基因。 |
Putnam, C. D. |
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The Saccharomyces cerevisiae cell lysis mutant cly8 is a temperature-sensitive allele of ESP1 |
| 人鼠蛋白质组学揭示了阿尔茨海默病与淀粉体中蛋白质周转延迟的共同通路 |
Yarbro, J. M. |
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N/A |
Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome |
| EpigeneticAgePipeline：一个用于从甲基化微阵列全面评估表观遗传年龄指标的R包 |
Rayevskiy, S. |
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N/A |
EpigeneticAgePipeline: an R package for comprehensive assessment of epigenetic age metrics from methylation microarrays |
| 重建过去的插入缺失的算法：仅删除的简约性问题 |
Moutet, J. |
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N/A |
Algorithms to reconstruct past indels: the deletion-only parsimony problem |
| 胶质母细胞瘤化疗耐药性的获得和逆转是由Rho GTPase通路介导的。 |
Magalhaes, Y. T. |
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N/A |
Acquisition and reversal of glioblastoma chemoresistance are mediated by the Rho GTPase pathway |
| CHK1介导的TOP1催化活性调控抑制了复制和转录相关的基因组不稳定性 |
Majumdar, A. G. |
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CHK1-mediated regulation of TOP1 catalytic activity suppresses replication and transcription-associated genomic instability |
| 体内表达与SCA27A相关的FGF14突变会导致半合子不足及小脑浦肯野神经元放电受损 |
Ransdell, J. L. |
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In Vivo Expression of an SCA27A-linked FGF14 Mutation Results in Haploinsufficiency and Impaired Firing of Cerebellar Purkinje Neurons |
| 可分离的默认模式网络连接模式构成了精神病风险中不同症状的基础 |
Ajunwa, C. C. |
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N/A |
Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk |
| 听觉工作记忆在音乐能力与听觉流分离之间的关系中起中介作用。 |
Liu, M. |
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N/A |
Auditory working memory mediates the relationship between musicianship and auditory stream segregation |
| F-BAR蛋白CIP4和FBP17在皮层神经元的径向迁移和突起生长中发挥作用。 |
English, L. A. |
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N/A |
F-BAR proteins CIP4 and FBP17 function in cortical neuron radial migration and process outgrowth |
| 前脑岛中的多巴胺传递塑造了焦虑的神经编码 |
COUDERC, Y. |
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N/A |
Dopamine transmission in the anterior insula shapes the neural coding of anxiety |