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脑岛和颞上沟在社交决策中对人际内疚感和责任感的贡献 Gaedeke, M. PDF N/A Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions
一项关于拉尔氏菌复合体已知全球分布和宿主范围的元分析 Lowe-Power, T. PDF N/A A Meta-analysis of the known Global Distribution and Host Range of the Ralstonia Species Complex
系统性降钙素基因相关肽(CGRP)可修饰听觉和前庭终器的电位,并增加感觉超敏性。 Rahman, S. M. PDF N/A Systemic Calcitonin Gene-Related Peptide (CGRP) modifies auditory and vestibular end organ electrical potentials, and increases sensory hypersensitivities
利用果蝇探究多细胞生物多聚磷酸盐生物学:揭示新颖且保守的多聚磷酸盐功能 Sarkar, S. PDF N/A Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions
在鼠类成纤维细胞中,微管的全球排列和局部曲率对于波形蛋白和肌动蛋白的扰动具有较强的稳健性。 Blob, A. PDF N/A Global alignment and local curvature of microtubules in mouse fibroblasts are robust against perturbations of vimentin and actin
巨噬细胞特异性脂质纳米颗粒疗法通过巨噬细胞-上皮相互作用阻断肺部机械敏感性免疫 Mthunzi, L. PDF N/A Macrophage-specific lipid nanoparticle therapy blocks the lungs mechanosensitive immunity due to macrophage-epithelial interactions
大型生物银行队列中随访数据的分析:方法学综述 Kolde, A. PDF N/A Analysis of follow-up data in large biobank cohorts: a review of methodology
在诱导多能干细胞衍生的神经元中进行的CRISPR筛选揭示了tau蛋白稳态的原理 Samelson, A. J. PDF N/A CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
邻域内相关性在植物间相互作用中的作用:对黑杨高度生长和锈病损害的影响 Tiret, M. PDF N/A The role of relatedness within a neighborhood in plant-to-plant interaction: effect on height growth and rust damage in Populus nigra
炎症小体主要限制了胞质内沙门氏菌在人类巨噬细胞中的复制 Egan, M. S. PDF N/A Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages
火烈鸟参与多种细胞竞争模式 Bosch, P. S. PDF N/A Flamingo participates in multiple models of cell competition
ATP释放的缝隙连接通道受溶血磷脂调控 Henze, E. PDF N/A ATP-release pannexin channels are gated by lysophospholipids
扩张型心肌病相关RNA结合基序蛋白20调控神经元中的长前体mRNA Di Bartolomei, G. PDF N/A Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons
休息期间的记忆巩固会在认知地图中形成捷径 Shearer, C. M. PDF N/A Memory consolidation during rest forms shortcuts in a cognitive map
ABC转运蛋白BmrA的构象变化依赖于膜曲率 Damm, A. PDF N/A Conformational changes of the ABC Transporter BmrA Depend on Membrane Curvature
多样执行功能全基因组关联研究的基因组SEM模型提高了基因发现 Perry, L. C. PDF N/A GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene Discovery
克服“饥饱”效应:全基因组关联研究中的改进交互测试 Zhou, H. PDF N/A Overcoming the "feast or famine" effect: improved interaction testing in genome-wide association studies
慢性血栓栓塞性肺动脉高压中肺血管树的内皮特征:独特还是共有的方面? Verhaegen, J. PDF N/A Endothelial features along the pulmonary vascular tree in chronic thromboembolic pulmonary hypertension: distinctive or shared facets?
环节动物幼虫的全身体连接组 Veraszto, C. PDF N/A Whole-body connectome of a segmented annelid larva
18种人类癌症基因表达的深度分析 Qiu, W. PDF N/A A deep profile of gene expression across 18 human cancers
自噬蛋白ATG14通过防止非计划性细胞焦亡的激活,在早期妊娠期间确保胚胎运输的安全进行。 POPLI, P. PDF N/A The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy
角质形成细胞中Semaphorin 4A的下调反映了非皮损性银屑病的特征。 Kume, M. PDF N/A Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis
Nicheformer:单细胞和空间组学的基石模型 Schaar, A. C. PDF N/A Nicheformer: a foundation model for single-cell and spatial omics
在羊膜动物原肠胚形成过程中,左右组织形成之前,双侧细胞流动显示出不对称性。 Asai, R. PDF N/A Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation
高加索侏儒虾虎鱼(Knipowitschia cf. caucasica)染色体水平基因组参考,这是一种新入侵莱茵河的虾虎鱼科外来物种 Schoenle, A. PDF N/A Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine
评估用于非靶向代谢组学的提取溶剂,以解析南极冰岩洞中溶解有机物的成分 Mundhe, S. D. PDF N/A Evaluation of extraction solvents for untargeted metabolomics to decipher the dissolved organic matter of Antarctic cryoconite holes
青蒿琥酯、EDTA和多粘菌素联合作用对MCR阴性和阳性的多粘菌素耐药沙门氏菌具有协同抗菌效果。 Zhai, Y. PDF N/A Artesunate, EDTA and colistin work synergistically against MCR-negative and -positive colistin-resistant Salmonella
执行资源塑造了语言可预测性在整个成年期内的影响 Schuckart, M. M. PDF N/A Executive Resources Shape the Effects of Language Predictability Across the Adult Lifespan
开放通道液滴微流控平台用于被动生成人类精子微滴 Nicholson, T. M. PDF N/A Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets
在颜色不显眼的青蛙中被动积累生物碱,精炼了后天化学防御的进化范式。 Tarvin, R. D. PDF N/A Passive accumulation of alkaloids in inconspicuously colored frogs refines the evolutionary paradigm of acquired chemical defenses
幅度熵用于捕捉癫痫发作期间脑动力学改变中的类嵌合体行为 Ghosh, S. PDF N/A Amplitude entropy to capture chimera-like behavior in the altered brain dynamics during seizures
稀疏标注足以用于启动密集分割的训练 Thiyagarajan, V. V. PDF N/A Sparse Annotation is Sufficient for Bootstrapping Dense Segmentation
优化One-Pot PURE系统中的蛋白质生产:对反应组成和表达效率的见解 Zhang, Y. PDF N/A Optimizing protein production in the One-Pot PURE system: insights into reaction composition and expression efficiency
镁通过调节磷脂代谢促进细菌对抗生素的表型抗性 Li, H. PDF N/A Magnesium modulates phospholipid metabolism to promote bacterial phenotypic resistance to antibiotics
TissueViewer:基于网络的多重图像查看器 van IJzendoorn, D. G. P. PDF N/A TissueViewer: A Web-Based Multiplexed Image Viewer
生态进化引导的路径组学分析用于预测DCIS升级 Xiao, Y. PDF N/A Eco-evolutionary Guided Pathomic Analysis to Predict DCIS Upstaging
GlyT2阳性中间神经元调控小脑-行为回路中信息传递的时间和变异性 Palacios, E. R. PDF N/A GlyT2-positive interneurons regulate timing and variability of information transfer in a cerebellar-behavioural loop
“微离线收益”对运动技能学习没有益处 Das, A. PDF N/A "Micro-offline gains" convey no benefit for motor skill learning
NF-κB表观遗传吸引子景观驱动乳腺癌异质性 Lopes, F. J. P. PDF N/A NF-κB Epigenetic Attractor Landscape Drives Breast Cancer Heterogeneity
流感病毒感染经历会改变肺结构细胞的动态,从而在病毒再次挑战后迅速获得免疫保护。 Worrell, J. C. PDF N/A Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
流感病毒感染经历会改变肺结构细胞的动态,从而在病毒再次挑战后迅速获得免疫保护。 Worrell, J. C. PDF N/A Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
苏云金芽孢杆菌库尔斯塔克亚种施用对加拿大东部北方森林中非目标夜行性大蛾生物多样性的影响。 Young, J. O. PDF N/A Effects of Bacillus thuringiensis subsp. kurstaki application on non-target nocturnal macromoth biodiversity in the eastern boreal forest, Canada.
巴西大西洋森林中不同土地覆盖类型的相对易燃性 Adorno, B. F. PDF N/A Relative fire-proneness of land cover types in the Brazilian Atlantic Forest
链藻类NMCP类核纤层蛋白的结构多样性与分布 Kosztyo, B. S. PDF N/A Structural diversity and distribution of NMCP-class nuclear lamina proteins in streptophytic algae
距离预测的神经表征精度与算术表现相关 Zhao, H. PDF N/A Neural Representation Precision of Distance Predicts Arithmetic Performance
转录因子Chronophage/BCL11A/B促进肠干细胞增殖和内分泌分化 King, E. A. PDF N/A The transcription factor Chronophage/BCL11A/B promotes intestinal stem cell proliferation and endocrine differentiation
人类遗传祖先、结核分枝杆菌多样性与坦桑尼亚达累斯萨拉姆市结核病严重程度的关系 Zwyer, M. PDF N/A Human genetic ancestry, Mycobacterium tuberculosis diversity and tuberculosis disease severity in Dar es Salaam, Tanzania
体内抗体标记途径和荧光染料决定了标记效率、灵敏度和持久性 Hagan, N. B. PDF N/A In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity
快速且准确的LSTM元建模体外TNF诱导的肿瘤抗性 Abrate, M. P. PDF N/A Fast and Accurate LSTM Meta-modeling of TNF-induced Tumor Resistance In Vitro
RRx-001在实验性子宫内膜异位症小鼠模型中的临床前测试显示出有前景的治疗效果。 McIntyre, I. PDF N/A Preclinical testing of RRx-001 in mouse models of experimental endometriosis reveals promising therapeutic impacts
量化面肩肱型肌营养不良症的抗DUX4疗法 Cowley, M. V. PDF N/A Quantifying anti-DUX4 therapy for facioscapulohumeral muscular dystrophy
转录因子SlMYB41、SlMYB92和SlWRKY71调控番茄外皮层基因表达 Jo, L. PDF N/A Transcription factors SlMYB41, SlMYB92 and SlWRKY71 regulate gene expression in tomato exodermis
识别质膜孔蛋白在质膜孔中的存在 Schladt, T. M. PDF N/A Identification of nuclear pore proteins at plasmodesmata
在皮层和丘脑中,典型的突触和神经元特性的发育可以在没有小胶质细胞的情况下进行。 O'Keeffe, M. PDF N/A Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus
使用Exeter Multiscope自动测量心肌细胞单层收缩 Corbett, A. D. PDF N/A Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope
一种新型的小鼠前肢生物力学模型预测了在抓取运动的最优控制模拟中的肌肉活动 Gilmer, J. I. PDF N/A A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements
脊髓V1中间神经元的转录组图谱揭示了En1在运动输出特定元素中的作用 Trevisan, A. J. PDF N/A The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output
在斑马鱼神经杆内局部光遗传激活NMYII会导致长距离、不对称的力量传播 Crellin, H. A. PDF N/A Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation
SC-MAMBA2:利用状态空间模型实现高效的单细胞超长转录组建模 Zhao, Y. PDF N/A SC-MAMBA2: Leveraging State-Space Models for Efficient Single-Cell Ultra-Long Transcriptome Modeling
一项简单的措施减少了小鼠的高脂肪饮食摄入和肥胖 Barrett, M. R. PDF N/A A simple action reduces high fat diet intake and obesity in mice
FIP 1.0数据集:高分辨率标注的4000个小麦地块在六年间的图像时间序列 Roth, L. PDF N/A The FIP 1.0 Data Set: Highly Resolved Annotated Image Time Series of 4,000 Wheat Plots Grown in Six Years
结合扩展显微技术和邻近标记技术揭示了锥虫核孔中保守且独特的非对称功能枢纽 Gabiatti, B. P. PDF N/A A combination of expansion microscopy and proximity labelling reveals conserved and unique asymmetric functional hubs at the trypanosome nuclear pore
从非靶向代谢组学数据中直接经验性地建立药物暴露记录 Zhao, H. N. PDF N/A Empirically establishing drug exposure records directly from untargeted metabolomics data
星形胶质细胞的区域特化是由出生后的发育过程塑造的。 Schroeder, M. E. PDF N/A Astrocyte regional specialization is shaped by postnatal development
气溶胶化合物对肺表面活性剂破坏作用的实验与建模 Barlow, H. J. PDF N/A Experiments and modelling of pulmonary surfactant disruption by aerosolised compounds
B细胞表达的酶PexRAP(乙醚脂质生物合成中的中间体)促进了抗体反应和生发中心的大小。 Cho, S. H. PDF N/A B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
比较系统性垂体腺苷酸环化酶激活肽(PACAP)和降钙素基因相关肽(CGRP)对小鼠运动诱导的恶心及平衡行为的影响 Rahman, S. M. PDF N/A Comparing The Impact of Systemic Pituitary Adenylate-Cyclase-Activating Polypeptide (PACAP) and Calcitonin Gene-Related Peptide (CGRP) on Motion-Induced Nausea And Balance Behaviors In Mice
Bur1驱动的G1-到S期转变诱导了酵母检查点突变体对羟基脲的敏感性 da Silva, S. C. R. PDF N/A Bur1-driven G1-to-S phase transition induces hydroxyurea sensitivity in yeast checkpoint mutants
周期蛋白-G相关激酶(GAK)是一种新型的有丝分裂激酶,也是弥漫性大B细胞淋巴瘤的治疗靶点。 Lightfuss, O. B. PDF N/A The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma
通过完整组装揭示了小鼠亚种间端粒和着丝粒的结构多样性 Francis, B. PDF N/A The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies
精神分裂症和健康个体中持续存在的深层脑部形态和不对称性的性别差异:ENIGMA-精神分裂症工作组的元分析 Cimmino, D. B. PDF N/A Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group
CRB2耗竭诱导YAP信号传导并破坏足细胞的机械感应 Sun, Y. PDF N/A CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。 Georgiadou, A. PDF N/A Anemia and tissue hypoxia are major determinants of malarial hypelactatemia
仿生光纳米生物界面实现了多尺度生物调控 Mueller, C. PDF N/A Biomimic opto-nanobiointerface enables multiscale biomodulation
用于检测纳米孔直接RNA测序中嵌合体伪影的基因组语言模型 Li, Y. PDF N/A A Genomic Language Model for Chimera Artifact Detection in Nanopore Direct RNA Sequencing
停留时间对视觉和被动引入运动情境效果的影响 Alvarez-Hidalgo, L. PDF N/A The impact of dwell time on the contextual effect of visual and passive lead-in movements
由光栅响应构建的编码流形在皮质视觉区域中组织了对自然场景的响应 Dyballa, L. PDF N/A Encoding manifolds constructed from grating responses organize responses to natural scenes in cortical visual areas
阿尔茨海默病进展过程中情景记忆网络的功能障碍 Lattmann-Grefe, R. PDF N/A Dysfunction of the episodic memory network in the Alzheimer's disease cascade
普通狨猴的拉绳行为 Bertrand, M. PDF N/A String-pulling by the common marmoset
抑制RNA调节因子HuR可有效缓解脊髓损伤,通过强力抑制损伤后的神经炎症。 Husain, M. A. PDF N/A Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation
避孕药和激素相关功能连接组在月经周期中的特异性和普遍性 Bottenhorn, K. L. PDF N/A Idiosyncrasy and generalizability of contraceptive- and hormone-related functional connectomes across the menstrual cycle
共享和独特的终身压力源特征以及大脑网络预测青少年焦虑和抑郁 Qu, Y. PDF N/A Shared and unique lifetime stressor characteristics and brain networks predict adolescent anxiety and depression
结合组织病理学和机器学习的人工智能网络能够提取自闭症谱系障碍中的轴突病理。 Yazdanbakhsh, A. PDF N/A Artificial intelligence networks combining histopathology and machine learning can extract axon pathology in autism spectrum disorder
一种三维免疫标记方法,结合了过氧化物酶融合的纳米抗体和荧光素标记的酪胺-葡萄糖氧化酶信号放大技术 Yamauchi, K. PDF N/A A Three Dimensional Immunolabeling Method with Peroxidase-fused Nanobodies and Fluorochromized Tyramide-Glucose Oxidase Signal Amplification
解码嗅球输出:行为评估速率、同步性和呼吸相位编码 Fu, X. PDF N/A Decoding Olfactory Bulb Output: A Behavioral Assessment of Rate, Synchrony, and Respiratory Phase Coding
一种新型基于菁染料的荧光染料用于神经毒性条件下和体内脑研究的靶向线粒体成像 Bi, L. PDF N/A A Novel Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging in Neurotoxic Conditions and In Vivo Brain Studies
顶叶后皮质介导由稀有性引发的决策偏差及在不确定性下的学习过程。 Sheng, W. PDF N/A Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty
早期对体液稳态的干扰会改变下丘脑摄食回路的发育,并导致摄食行为的特定情境变化。 Sweet, S. R. PDF N/A Early perturbations to fluid homeostasis alter development of hypothalamic feeding circuits with context-specific changes in ingestive behavior
EEG-VLM工具箱:将体素化病变映射扩展至多维脑电数据 Hardstone, R. PDF N/A EEG-VLM Toolbox: Extending voxel-based lesion mapping to multi-dimensional EEG data
UBR4、LRP1 和 OPHN1 在难治性癫痫中的相互作用:利用果蝇模型研究癫痫的多基因效应 Huang, R.-N. PDF N/A The Interaction of UBR4, LRP1, and OPHN1 in Refractory Epilepsy: Drosophila Model to Investigate the Oligogenic Effect on Epilepsy
产卵抑制神经元是果蝇大脑中多电路整合的潜在枢纽 Weber Langstaff, R. PDF N/A The Oviposition Inhibitory Neuron is a potential hub of multi-circuit integration in the Drosophila brain
摩擦系数之外的选择:精细触觉感知依赖于摩擦不稳定性 Derkaloustian, M. PDF N/A Alternatives to Friction Coefficient: Fine Touch Perception Relies on Frictional Instabilities
高精度神经反馈引导的冥想训练优化了现实世界中自我引导的冥想实践,以促进福祉。 Ganesan, S. PDF N/A High-precision neurofeedback-guided meditation training optimises real-world self-guided meditation practice for well-being
在个人空间中的多感官整合可以反映睡眠和意识障碍中的意识状态 Bertoni, T. PDF N/A Multisensory integration in Peripersonal Space indexes consciousness states in sleep and disorders of consciousness
显式获取的心理模式间相互关系降低认知负荷并促进小鼠和人工神经网络中新颖反应的出现。 Singh, V. P. PDF N/A Explicitly Acquired Interrelations Among Mental Schema Reduces Cognitive Load and Facilitates Emergence of Novel Responses in Mice and Artificial Neural Networks.
青春期C57BL/6J小鼠在单次暴饮乙醇暴露后情境消退学习的性别差异 Cardona-Jordan, K. M. PDF N/A Sex Differences in Contextual Extinction Learning After Single Binge-Like EtOH Exposure in Adolescent C57BL/6J Mice
在青光眼小鼠模型中,小胶质细胞对眼内压升高和视觉丘脑突触丢失做出反应。 Thompson, J. L. PDF N/A Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucoma.
连接蛋白43介导的线粒体转移可预防顺铂诱导的感觉神经退行性变。 Owen, B. PDF N/A Connexin 43 mediated mitochondrial transfer prevents cisplatin induced sensory neurodegeneration.
“迷你分析”是突触变化的不可靠报道者 Greger, I. H. PDF N/A 'Mini analysis' is an unreliable reporter of synaptic changes
使用-SynVesT-1-成像技术研究衰老和阿尔茨海默病中的突触密度 Giorgio, J. PDF N/A Imaging synaptic density in ageing and Alzheimer's Disease with -SynVesT-1
测试测试:利用基于连接组学的预测模型揭示标准化测试和临床症状所反映的系统 Samardzija, A. PDF N/A Testing the Tests: Using Connectome-Based Predictive Models to Reveal the Systems Standardized Tests and Clinical Symptoms Are Reflecting
在原条延伸期间及之后,中线模式对有丝分裂的敏感性存在差异 Zhao, Z. PDF N/A Differential Sensitivity of Midline Patterning to Mitosis during and after Primitive Streak Extension
小鼠跟腱成熟过程中的单核转录组和染色质可及性分析揭示了腱干细胞/祖细胞的分子图谱 Asahara, H. PDF N/A Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells
果蝇Trus,哺乳动物PDCD2L的直系同源基因,对于正常的细胞增殖、幼虫发育时序以及卵子发生是必需的。 Takada, S. PDF N/A Drosophila Trus, the orthologue of mammalian PDCD2L, is required for proper cell proliferation, larval developmental timing, and oogenesis
涡虫在反复接触电离辐射后发展出辐射耐受性 Barghouth, P. G. PDF N/A Planarians Develop Radiotolerance to Recurrent Ionizing Radiation Exposure
Abl激酶通过调节FGF信号传导,独立于Crk磷酸化,以防止彼得氏异常。 Wu, H. PDF N/A Abl kinases regulate FGF signaling independent of Crk phosphorylation to prevent Peters anomaly
Irx3/5 定义了耳蜗的感觉域,并调节哺乳动物内耳的前庭和耳蜗感觉模式。 Liu, Y. PDF N/A Irx3/5 define the cochlear sensory domain and regulate vestibular and cochlear sensory patterning in the mammalian inner ear
肺发育过程中初级纤毛和运动纤毛的时空动态变化 Spurgin, S. PDF N/A Spatiotemporal dynamics of primary and motile cilia throughout lung development
子宫基质而非上皮中的PTGS2对小鼠妊娠成功至关重要 Massri, N. PDF N/A Uterine stromal but not epithelial PTGS2 is critical for murine pregnancy success
塑造小鼠和沙鼠尾巴椎骨比例发育和进化的细胞和分子机制 Weber, C. J. PDF N/A Cellular and molecular mechanisms that shape the development and evolution of tail vertebral proportion in mice and jerboas
早期背侧胰腺芽中Hippo信号通路组分的表征 Ahuja, N. H. PDF N/A Characterization of Hippo Signaling Components in the Early Dorsal Pancreatic Bud
IntelliProfiler:一种用于分析多个动物在家庭笼中行为动态的新型分析工具 Ochi, S. PDF N/A IntelliProfiler: a novel analytic tool for behavior dynamics of multiple animals in a home cage
背侧纹状体神经炎症通过破坏稳态星形胶质细胞功能导致过度目标导向行为控制 Abiero, A. R. PDF N/A Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting homeostatic astrocyte function
社会经验塑造了为繁殖成功而战的策略 Gao, C. PDF N/A Social Experience Shapes Fighting Strategies for Reproductive Success
持续整合航向和目标方向以引导转向 Crown, A. M. PDF N/A Continuous integration of heading and goal directions guides steering
在自然视觉过程中,人类视觉皮层早期的感觉反应最好由扫视(saccade)的开始,而非注视(fixation)的开始来解释。 Amme, C. PDF N/A Saccade onset, not fixation onset, best explains early sensory responses across the human visual cortex during naturalistic vision
身体游离揭示了思维的具身维度,具有独特的影响和神经特征。 Banellis, L. PDF N/A Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures
奖励激发等长握持动作 Marbaker, R. M. PDF N/A Reward invigorates isometric gripping actions
在模拟激活阈值时,统计方法考虑了神经元周围微观电场的畸变。 Weise, K. PDF N/A Statistical method accounts for microscopic electric field distortions around neurons when simulating activation thresholds
神经系统中降钙素基因相关受体成分蛋白(RCP)的缺失可偏向于gepant拮抗作用 Rahman, S. PDF N/A Loss of Calcitonin gene-related Related Receptor component protein (RCP) in nervous system can bias gepant antagonism
使用指数梯度进行类脑学习 Cornford, J. PDF N/A Brain-like learning with exponentiated gradients
第三人称视角冥想调节了最小自我和心跳引发的电位 Yang, H. PDF N/A Meditation in the third-person perspective modulates minimal self and heartbeat-evoked potentials
慢性激活皮质脊髓束神经元在锥体束切断术后既不能增强行为恢复,也不能促进轴突萌发。 Wang, Z. PDF N/A Chronic activation of corticospinal tract neurons after pyramidotomy injury enhances neither behavioral recovery nor axonal sprouting
Ybx1引导C/EBPα和cBAF染色质重塑复合物,促进脂肪变性肝细胞中的脂肪生成基因表达。 Jordan, J. M. PDF N/A Ybx1 guides C/EBPα and cBAF chromatin-remodeling complex to promote adipogenic gene expression in steatotic hepatocytes
单核细胞衍生的CXCL12引导斑马鱼血管的定向迁移 Liu, D. PDF N/A Monocytes-derived cxcl12 guides a directional migration of blood vessels in zebrafish
定量解析秀丽隐杆线虫早期胚胎发育中的细胞命运 Xiong, R. PDF N/A Quantitative Resolving Cell Fate in the Early Embryogenesis of Caenorhabditis elegans
三刺鱼通过面部识别来识别熟悉的个体。 SOGAWA, S. PDF N/A Three-spined sticklebacks recognise familiar individuals by facial recognition
静息态功能连接在音频触觉语音训练后的变化 Ciesla, K. PDF N/A Resting-state functional connectivity changes following audio-tactile speech training
外显的视觉注意在腹侧和背侧内侧前额叶皮层中调节与决策相关的信号 Shevlin, B. R. K. PDF N/A Overt visual attention modulates decision-related signals in ventral and dorsal medial prefrontal cortex
Gb3三糖基化外泌体作为志贺毒素1型的新型中和剂 Mikolajczyk, K. PDF N/A Gb3 trisaccharide-bearing exosomes as a novel neutralizer for Shiga toxin type 1
原核生物和噬菌体中抗病毒防御系统的基因组景观 Li, J. PDF N/A Genomic landscape of antiviral defense systems in prokaryotes and phages
胚胎氧水平的变化提示了肢体起始的异时性。 Zhu, M. PDF N/A Shifts in embryonic oxygen levels cue heterochrony in limb initiation
空间定量代谢组学能够识别中风后对侧皮质代谢重编程的远距离和持续性 Wang, G. PDF N/A Spatial quantitative metabolomics enables identification of remote and sustained ipsilateral cortical metabolic reprogramming after stroke
拟南芥中鼠李半乳糖醛酸聚糖-I(RG-I)的深层结构分析揭示了果胶多样性的新见解 Zhang, L. PDF N/A Deep structural analysis of rhamnogalacturonan-I (RG-I) in Arabidopsis reveals new insights into pectin diversity
UBA5抑制剂的鉴定与表征 Singh, V. PDF N/A Identification and characterization of UBA5 inhibitors
合理设计的鼻腔微生物群落体外代谢相互作用网络 Bonillo-Lopez, L. PDF N/A In vitro metabolic interaction network of a rationally designed nasal microbiota community
Malat1通过控制早期分化和对IL2的反应来调节女性Th2细胞的细胞因子表达。 Gwynne, M. PDF N/A Malat1 regulates female Th2 cell cytokine expression through controlling early differentiation and response to IL2
生物相互作用塑造了拟南芥中的感染结果 Mahmoudi, M. PDF N/A Biotic interactions shape infection outcomes in Arabidopsis
混合物中噬菌体的生命史特征决定了共感染的动态和效力 Khan, R. PDF N/A The life history traits of phages in a cocktail determine coinfection dynamics and efficacy
三种CRISPR-Cas类型之间的交叉对话使李斯特菌seeligeri中的引发型VI-A适应成为可能 Margolis, S. R. PDF N/A Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri
表达胸苷激酶的黄热病17D报告病毒有助于前药激活和感染细胞的生物正交标记 Yakass, M. B. PDF N/A Thymidine kinase-expressing yellow fever 17D reporter virus facilitates prodrug activation and bioorthogonal labelling of infected cells
由tafazzin控制的线粒体心磷脂代谢能够促进铁死亡 Wohlfarter, Y. PDF N/A Mitochondrial cardiolipin metabolism controlled by tafazzin enables ferroptosis
探索南大洋渔业变化机制:基于合作生产网络模型 Ward, D. PDF N/A Exploring mechanisms of change in a Southern Ocean fishery with a co-produced network model
长期变暖会颠倒生态系统功能与微生物资源获取之间的关系。 Shinfuku, M. S. PDF N/A Long-term warming inverts the relationship between ecosystem function and microbial resource acquisition
海藻全生物的季节性循环:多年时间序列揭示了重复的微生物变化和核心类群 Mudlaff, C. M. PDF N/A Seasonal cycles in a seaweed holobiont: A multiyear time series reveals repetitive microbial shifts and core taxa
揭示不同人类免疫细胞中转座元件介导的调控景观 Du, C. PDF N/A Unraveling transposable element-mediated regulatory landscape in diverse human immune cells
携带III型分泌系统2(T3SS2)和副溶血性弧菌TDH毒素的米氏弧菌在整合接合元件背景下的研究 Morgado, S. PDF N/A Vibrio mimicus carrying the Type III Secretion System 2 (T3SS2) and TDH toxin of Vibrio parahaemolyticus in an integrative conjugative element context
肾缺血-再灌注损伤后细胞状态和选择性剪接的动态变化 Markiewitz, D. PDF N/A Dynamics of cell states and alternative splicing following kidney ischemia-reperfusion injury
弧菌超整合子中ST热稳定肠毒素基因盒的表达模式 Fonseca, E. L. PDF N/A Expression pattern of the ST heat-stable enterotoxin gene cassettes in Vibrios superintegrons
一种序列特异性的RNA乙酰化催化剂 Thalalla Gamage, S. PDF N/A A sequence-specific RNA acetylation catalyst
表达人α1,4-半乳糖基转移酶的B4GALT5缺陷CHO-Lec2细胞:用于研究志贺毒素受体的糖工程细胞模型 Mikolajczyk, K. PDF N/A B4GALT5-deficient CHO-Lec2 cells expressing human alpha1,4-galactosyltransferase: a glycoengineered cell model for studying Shiga toxin receptors
人类MUTYH的结构及其癌症相关变体的功能分析揭示了其辅因子簇与活性位点之间的变构网络,这对DNA修复至关重要。 Trasvina-Arenas, C. H. PDF N/A Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its cluster cofactor and active site required for DNA repair
AlphaBridge:用于分析预测的大分子复合物的工具 Alvarez Salmoral, D. PDF N/A AlphaBridge: tools for the analysis of predicted macromolecular complexes
通过流形再现分析进行生成模型的验证 Lazzaro, N. PDF N/A Generative Models Validation via Manifold Recapitulation Analysis
在生理培养条件下以代谢为导向的化合物筛选发现了一种对未接受治疗和耐药黑色素瘤细胞具有高度抑制作用的NAMPT抑制剂。 Preis, J. R. PDF N/A Metabolism-oriented compound screen in physiological culture conditions identifies a NAMPT inhibitor highly effective against drug-naive and -resistant melanoma cells
确定同时抑制核黄素代谢和MEK作为胰腺癌的新型治疗策略 Ooshio, T. PDF N/A Identifying simultaneous inhibition of riboflavin metabolism and MEK as a novel therapeutic strategy for pancreatic cancer
精氨酸代谢的免疫原性转变触发了全身代谢和免疫系统的重新编程,以预防HER2阳性乳腺癌 Sharma, V. PDF N/A Immunogenic shift of arginine metabolism triggers systemic metabolic and immunological reprogramming to prevent HER2+ breast cancer
计算机预测和基因分析揭示了视黄酸调节作为遗传多样性秀丽隐杆线虫中保守的长寿通路的驱动因素 Banse, S. A. PDF N/A Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes
将DNA甲基化图谱与大鼠群中由β-肾上腺素能刺激引起的心脏病理联系起来 Lahue, C. PDF N/A Mapping DNA Methylation to Cardiac Pathologies Induced by Beta-Adrenergic Stimulation in a Large Panel of Mice
FicD AMP化失调通过破坏胰腺内分泌稳态导致糖尿病 Casey, A. K. PDF N/A Dysregulation of FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis

medRxiv

标题 作者 PDF链接 代码仓库 Title
全基因组关联研究揭示了活跃献血者的独特遗传结构 Clancy, J. PDF N/A Genome-wide association study reveals the unique genetic structure of active blood donors
自我逻辑一致的GPT-4实现了对患者反馈的人类级别分类 Loi, Z. PDF N/A Self-Logical Consistent GPT-4 Enables Human-Level Classification of Patient Feedback
评估一线2型糖尿病治疗在不同eGFR水平和医疗服务提供者之间的差异 Ji, C. X. PDF N/A Assessing Variation in First-Line Type 2 Diabetes Treatment across eGFR Levels and Providers
Echo-Vision-FM:一种针对超声心动图视频视觉基础模型的预训练与微调框架 Zhang, Z. PDF N/A Echo-Vision-FM: A Pre-training and Fine-tuning Framework for Echocardiogram Videos Vision Foundation Model