| 慢振荡-纺锤波耦合预测基于序列的语言学习 |
Cross, Z. R. |
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N/A |
Slow oscillation-spindle coupling predicts sequence-based language learning |
| 周期环境中的共存 |
Scott, A. M. |
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N/A |
Coexistence in Periodic Environments |
| 通过AAV外显子测序的CRISPR筛选（CrAAVe-seq）是一种高度可扩展的细胞类型特异性体内筛选平台。 |
Ramani, B. |
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N/A |
CRISPR screening by AAV episome-sequencing (CrAAVe-seq) is a highly scalable cell type-specific in vivo screening platform |
| 在巩固过程中，部分多巴胺能神经元的活动短暂中断，会通过破坏睡眠来损害长期记忆。 |
Yan, L. |
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N/A |
Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs long-term memory by fragmenting sleep |
| ExploreTurns：一种用于探索、分析和分类蛋白质中beta转角和结构化环的网络工具；应用于beta凸起环、Schell曼环、Asx螺旋帽、beta发夹及其他氢键连接基序 |
Newell, N. E. |
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N/A |
ExploreTurns: A web tool for the exploration, analysis, and classification of beta turns and structured loops in proteins; application to beta-bulge and Schellman loops, Asx helix caps, beta hairpins and other hydrogen-bonded motifs |
| 非人类灵长类动物中决策与运动相互作用但解耦控制的证据 |
Saleri, C. |
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N/A |
Evidence for interacting but decoupled controls of decisions and movements in non-human primates |
| 人道主义背景下无性繁殖作物面临的病原体和害虫风险：为喀麦隆和埃塞俄比亚制定国家植物健康风险分析 |
Mouafo-Tchinda, R. |
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N/A |
Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Towards a national plant health risk analysis for Cameroon and Ethiopia |
| Dravet综合征Scn1a+/-小鼠的神经发育缺陷：靶向GABA开关可挽救行为功能障碍，但不能改善癫痫发作和死亡率。 |
Pizzamiglio, L. |
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N/A |
Neurodevelopmental defects in Dravet syndrome Scn1a+/- mice: targeting GABA-switch rescues behavioral dysfunctions but not seizures and mortality. |
| 3DCellComposer - 一种利用2D细胞分割方法进行3D细胞分割的多功能管道 |
Chen, H. |
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N/A |
3DCellComposer - A Versatile Pipeline Utilizing 2D Cell Segmentation Methods for 3D Cell Segmentation |
| 婴儿脑电图中眼球运动伪迹的校正 |
Srishyla, D. |
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N/A |
Eye-movement artifact correction in infant EEG |
| 从背外侧前额叶皮层的转录组和表观基因组数据推断阿尔茨海默病女性患者的潜在多重疾病进展途径 |
Honda, K. |
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N/A |
Potential multiple disease progression pathways in female patients with Alzheimer's disease inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex |
| 利用生成式人工智能方法推进多器官毒性评估的跨器官转录组学研究 |
Li, T. |
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N/A |
Bridging Organ Transcriptomics for Advancing Multiple Organ Toxicity Assessment with a Generative AI Approach |
| MGPfactXMBD：一种基于模型的分解方法，用于单细胞RNA数据，揭示了细胞命运决定背后的分叉转录模块 |
Ren, J. |
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N/A |
MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination |
| 杀婴行为是由对后代位置的不熟悉所驱动的，并与模仿毒蛙中的雄激素变化相关联。 |
Lewis, A. R. |
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N/A |
Infanticide is driven by unfamiliarity with offspring location and associated with androgenic shifts in mimic poison frogs |
| 鲁迪拉介导的微管稳定性调控在小鼠血管发育过程中TGFβ信号传导 |
Joshi, D. |
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N/A |
Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development |
| 优先处理工作记忆资源取决于前额叶皮层 |
Hallenbeck, G. E. |
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N/A |
Prioritizing working memory resources depends on prefrontal cortex |
| 寄生虫释放的敌对力量在入侵的非洲无花果蝇（Zaprionus indianus）中是情境依赖的。 |
Walsh-Antzak, C. R. |
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N/A |
Strength of enemy release from parasitoids is context-dependent in the invasive African Fig Fly, Zaprionus indianus |
| 禽源沙门氏菌肠炎沙门氏菌血清型鸡白痢向地方性转变的过程中伴随着局部抗性组和移动组的相互作用。 |
Jia, C. |
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N/A |
Avian-specific Salmonella enterica Serovar Gallinarum transition to endemicity is accompanied by localized resistome and mobilome interaction |
| 长寿的软骨祖细胞由胎儿肢体的Gli1+细胞产生，并在软骨中的镶嵌细胞周期停滞时得到补充。 |
Qu, X. |
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N/A |
Long-lived chondroprogenitors are generated by fetal-limb Gli1+ cells and are replenished upon mosaic cell-cycle arrest in the cartilage |
| 全原子连续恒定pH分子动力学的力场限制 |
Peeples, C. |
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N/A |
Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics |
| 人类4D核组结构与功能的综合视角 |
The 4D Nucleome Consortium, |
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N/A |
An integrated view of the structure and function of the human 4D nucleome |
| 氯胺酮通过在小鼠中表达钙离子通透性AMPA受体来逆转慢性应激引起的行为变化。 |
Flowers, J. C. |
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N/A |
Ketamine reverses chronic stress-induced behavioral changes via the expression of Ca2+-permeable AMPA receptors in mice |
| 免疫-病原体共进化中的信息处理适应性效率 |
Bellamy, Q. N. |
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N/A |
Adaptive efficiency of information processing in immune-pathogen co-evolution |
| 自由觅食的猕猴在模糊地形中重视信息 |
Shahidi, N. |
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N/A |
Freely foraging macaques value information in ambiguous terrains |
| 单个癌细胞中多种ecDNA类型的维持 |
Scanu, E. |
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N/A |
The maintenance of multiple ecDNA types in single cancer cells |
| 前脑岛中的多巴胺传递塑造了焦虑的神经编码 |
COUDERC, Y. |
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N/A |
Dopamine transmission in the anterior insula shapes the neural coding of anxiety |
| 停留时间对视觉和被动导入运动情境效应的影响 |
Alvarez-Hidalgo, L. |
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N/A |
The impact of dwell time on the contextual effect of visual and passive lead-in movements |
| 抑制RNA调节因子HuR可有效缓解脊髓损伤，通过强力抑制损伤后的神经炎症。 |
Husain, M. A. |
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N/A |
Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation |
| 后顶叶皮层介导由稀有性引发的决策偏差及不确定性下的学习 |
Sheng, W. |
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N/A |
Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty |
| UBA5抑制剂的鉴定与表征 |
Singh, V. |
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N/A |
Identification and characterization of UBA5 inhibitors |
| 计算识别空间转录组学数据中的迁移T细胞 |
Zhong, L. |
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N/A |
Computational Identification of Migrating T cells in Spatial Transcriptomics Data |
| 基于特征的注意在人类皮层下核团功能分区中的空间全局效应 |
Lin, W. |
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N/A |
Spatially global effects of feature-based attention in functional subdivisions of human subcortical nuclei |
| 通过祖先X-Y染色体基因对Kdm5c-Kdm5d调控性别偏向基因表达 |
Malcore, R. M. |
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N/A |
Regulation of Sex-biased Gene Expression by the Ancestral X-Y Chromosomal Gene Pair Kdm5c-Kdm5d |
| 非洲起源的单体型对APOEϵ4携带者的阿尔茨海默病具有保护作用：探索潜在机制 |
Bertholim-Nasciben, L. |
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N/A |
African origin haplotype protective for Alzheimer's disease in APOEϵ4 carriers: exploring potential mechanisms |
| CD90识别出具有不同激活和静息维持模式的肌肉干细胞的不同亚群。 |
Kheir, E. |
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N/A |
CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance |
| 景天酸代谢在CAM植物Kalanchoë laxiflora中的蛋白质水平调控 |
Schiller, K. |
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N/A |
Regulation of Crassulacean Acid Metabolism at the protein level in the CAM plant Kalanchoë laxiflora |
| DNA甲基化年龄生物标志物具有响应性：来自51项人类长寿干预研究的见解 |
Sehgal, R. |
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N/A |
DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans |
| 室旁核中的Apelin-13通过室旁核的V1a受体和孤束核的GABAA受体γ2保护大鼠心肌免受缺血损伤。 |
yan, w. |
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N/A |
Apelin-13 in the paraventricular nucleus protects myocardium from ischemia via V1a receptor of the paraventricular nucleus and GABAA receptor γ2 of the nucleus tractus solitarii in rats |
| 多发性硬化脊髓中的异常铁沉积与神经退行性变有关 |
Pisa, M. |
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N/A |
Aberrant iron deposition in the multiple sclerosis spinal cord relates to neurodegeneration |
| 训练刺激的复杂特性影响深度网络模型中大脑视觉皮层的对齐 |
Torabian, P. |
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N/A |
Complex Properties of Training Stimuli Affect Brain Alignment in a Deep Network Model of Mouse Visual Cortex |
| 脂质氢同位素组成主要反映了模式古菌Sulfolobus acidocaldarius的生长水。 |
Harris, C. M. |
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N/A |
Lipid hydrogen isotope compositions primarily reflect growth water in the model archaeon Sulfolobus acidocaldarius |
| HIV-1包膜糖蛋白原体的化学计量学及其稳定或破坏预触发构象的变化 |
Zhang, Z. |
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N/A |
Stoichiometry of HIV-1 Envelope Glycoprotein Protomers with Changes That Stabilize or Destabilize the Pretriggered Conformation |
| NLGN3通过激活Gαi1/3-Akt通路促进心肌梗死中的血管生成 |
qiao, s. |
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N/A |
NLGN3 contributes to angiogenesis in myocardial infarction via activation of the Gαi1/3-Akt Pathway |
| 旁观者碱基编辑干扰了莱伯先天性黑蒙视觉功能的恢复 |
Lee, S.-H. |
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N/A |
Bystander base editing interferes with visual function restoration in Leber congenital amaurosis |
| 一种新型雄性附腺肽降低了褐飞虱雌性交配后的接受性 |
Zhang, Y.-J. |
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N/A |
A novel male accessory gland peptide reduces female post-mating receptivity in the brown planthopper |
| 一夜部分睡眠剥夺对血管周围空间体积分数的影响：来自斯德哥尔摩困倦大脑研究的发现 |
Custer, R. M. |
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N/A |
Effects of one-night partial sleep deprivation on perivascular space volume fraction: Findings from the Stockholm Sleepy Brain Study |
| 皮层6b层介导了与状态相关的大脑活动变化，以及食欲素对觉醒和睡眠的影响。 |
Meijer, E. J. |
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N/A |
Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep |
| 低剂量的A型和B型肉毒杆菌神经毒素有利于沙门氏菌和志贺氏菌的感染，而不会引起肉毒中毒的松弛性麻痹。 |
Fabris, F. |
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N/A |
Low Intestinal Doses of Botulinum Neurotoxins types A and B favour infection by Salmonella and Shigella without the flaccid paralysis of botulism |
| 斑马鱼中个体保守神经元微外显子的表型影响及其主调控因子 |
Lopez-Blanch, L. |
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N/A |
Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish |
| Foxi1通过转录和表观遗传机制调控粘液纤毛发育和离子细胞分化的多个步骤 |
Bowden, S. |
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N/A |
Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms |
| NOTCH1驱动肝细胞癌的肿瘤可塑性和转移 |
Lindblad, K. E. |
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N/A |
NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma |
| 一种结合计算模型，用于模拟癌症球体生长，涉及核糖诱导的胶原蛋白硬化 |
Botticelli, M. |
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N/A |
A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening |
| 特定领域的模式重用在灵长类大脑中支持灵活的学习 |
Tian, K. |
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N/A |
Domain-specific Schema Reuse Supports Flexible Learning to Learn in Primate Brain |
| 分泌型Clever-1调节T细胞反应并影响癌症免疫治疗效果 |
Prince, S. |
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N/A |
Secreted Clever-1 Modulates T Cell Responses and Impacts Cancer Immunotherapy Efficacy |
| 马达聚类增强驱动囊泡运输 |
Jiang, R. |
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N/A |
Motor Clustering Enhances Kinesin-driven Vesicle Transport |
| 利用人工智能自动化检测和量化染色体外DNA（ecDNA）以解码药物反应 |
Goble, K. |
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N/A |
Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses |
| 探索以丙酮酸为唯一碳源的细菌培养基的生化环境，用于核磁共振研究 |
Dag, C. |
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N/A |
Exploring the Biochemical Landscape of Bacterial Medium with Pyruvate as the Exclusive Carbon Source for NMR Studies |
| 优化复杂RNA系统的即时概率增强采样：采样H型假结的自由能表面 |
Malekzadeh, K. |
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N/A |
Optimizing On-the-Fly Probability Enhanced Sampling for Complex RNA Systems: Sampling Free Energy Surfaces of an H-Type Pseudoknot |
| 生态上截然不同的微生物群落降解有机物一致地促进植物生长 |
Lee, B. |
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N/A |
Degradation of organic matter by ecologically distinct microbiomes uniformly promotes plant growth |
| 果糖激活了链球菌突变体中与甲基乙二醛和过氧化氢共享的应激反应 |
Walker, A. R. |
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N/A |
FRUCTOSE ACTIVATES A STRESS RESPONSE SHARED BY METHYLGLYOXAL AND HYDROGEN PEROXIDE IN STREPTOCOCCUS MUTANS |
| 密螺旋体牙龈卟啉单胞菌穿梭质粒中蛋白质表达的功能表征与优化 |
Goetting-Minesky, M. P. |
PDF |
N/A |
Functional characterization and optimization of protein expression in Treponema denticola shuttle plasmids |
| 鲍曼不动杆菌的防御体系揭示了根据其先天防御系统和噬菌体特征划分的两个基因组群体。 |
Moreno-Rodriguez, A. |
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N/A |
The defensome of Acinetobacter baumannii reveals two genome groups according to their innate defense systems and phage profile |
| 病毒进入是单核细胞中人巨细胞病毒潜伏的主要决定因素 |
Kitsberg, Y. |
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N/A |
Virus Entry is a Major Determinant of HCMV Latency in Monocytes |
| 针对ADORA-PDE10 cAMP微域：肺动脉高压的新型治疗策略 |
Valasarajan, C. |
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N/A |
Targeting ADORA-PDE10 cAMP Microdomain: A Novel Therapeutic Approach for Pulmonary Hypertension |
| 比较元转录组学揭示了浮游动物对生活环境中营养异质性的生理反应 |
Nuruddin, M. F. |
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N/A |
Comparative meta transcriptomics uncovers the physiological responses of zooplankton to nutrient heterogeneity in their living environment |
| 整合的肝铁死亡基因特征决定了铁死亡的致病特征 |
Matsumoto, T. |
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N/A |
Integrated hepatic ferroptosis gene signature dictates pathogenic features of ferroptosis |
| 细菌接种可调控珊瑚的表观基因组 |
Barno, A. R. |
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N/A |
Bacterial inoculation manipulates the coral epigenome |
| 利用16S纳米孔测序增强海底生态状态预测 |
Philip, M. |
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N/A |
Enhanced Prediction of Seafloor Ecological State Using 16S Nanopore Sequencing |
| 飞行哺乳动物Rhinolophus hipposideros的配子散布几何结构 |
Brazier, T. |
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N/A |
The geometry of gametic dispersal in a flying mammal, Rhinolophus hipposideros |
| 伯氏疏螺旋体感染的肩突硬蜱中的表观遗传反应：常染色质组蛋白赖氨酸甲基转移酶2的过表达及DNA甲基化无变化 |
MacIntosh, G. H. |
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N/A |
Epigenetic responses in Borrelia-infected Ixodes scapularis ticks: Over-expression of euchromatic histone lysine methyltransferase 2 and no change in DNA methylation |
| 低覆盖率测序工作流程在茄子精准基因分型中的基准测试 |
Baraja-Fonseca, V. |
PDF |
N/A |
Benchmarking of Low Coverage Sequencing Workflows for Precision Genotyping in Eggplant |
| 六倍体燕麦的泛基因组和泛转录组 |
Avni, R. |
PDF |
N/A |
A pangenome and pantranscriptome of hexaploid oat |
| 巨型鳞翅目昆虫古共生体中加速的假基因化 |
Choi, J. |
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N/A |
Accelerated pseudogenization in ancient endosymbionts of giant scale insects |
| 环状RNA AEBP2：树突状细胞发育中的新型调控因子 |
Zhou, Q. |
PDF |
N/A |
Circular RNA AEBP2: A novel regulator in dendritic cell development |
| 利用拓扑机器学习识别靶向细菌丙酸代谢的分子化合物 |
Tola, A. |
PDF |
N/A |
Identification of Molecular Compounds Targeting Bacterial Propionate Metabolism with Topological Machine Learning |
| 可以利用mTOR-Tfeb-Fabp7a信号轴来改善成年斑马鱼中的bag3心肌病 |
Ding, Y. |
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N/A |
An mTOR-Tfeb-Fabp7a signaling axis can be harnessed to ameliorate bag3 cardiomyopathy in adult zebrafish |
| 剖析转座元件对间期染色体结构的贡献 |
Shi, L. |
PDF |
N/A |
Dissecting the Contribution of Transposable Elements to Interphase Chromosome Structure |
| 翻译：翻译后修饰调控孤儿受体GPR52的固有信号偏倚 |
Zhang, B. |
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N/A |
Post-translational modifications orchestrate the intrinsic signaling bias of orphan receptor GPR52 |
| 去氨甲酰化和未去氨甲酰化的eIF5A异构体在胰腺发育和功能模型中表现出不同的作用 |
Anderson, C. M. |
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N/A |
Hypusinated and unhypusinated isoforms of eIF5A exert distinct effects in models of pancreas development and function |
| PXGS：一种基于Dscam互斥剪接的多基因表达系统 |
Yu, R. Y. |
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N/A |
PXGS: a Poly-Transgene Expression System based on Mutually Exclusive Splicing of Dscam |
| 基因组范围内遗传扰动的相分离景观 |
Heidenreich, M. |
PDF |
N/A |
The phase separation landscape of genome-wide genetic perturbations |
| 肌动蛋白调节因子的时空协调作用在细胞融合过程中产生侵袭性突起 |
Lu, Y. |
PDF |
N/A |
Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion |
| IGF2通过介导Hippo信号通路来控制肝脏大小 |
Zhong, Z. |
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N/A |
IGF2 mediates Hippo signaling to control liver size |
| 全面蛋白质组学表征高尔基体内部运输中间体 |
Sumya, F. T. |
PDF |
N/A |
Comprehensive Proteomic Characterization of Intra-Golgi Trafficking Intermediates |
| 线粒体自噬调节在秀丽隐杆线虫（C. elegans）的uaDf5动物模型中，能够缓解单一大规模线粒体DNA缺失（SLSMD）疾病的症状。 |
Mendel, R. M. |
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N/A |
Mitophagy modulation rescues single large-scale mitochondrial DNA deletion (SLSMD) disease symptoms in the C. elegans uaDf5 animal model. |
| 通过表型药物筛选和药物设计开发新型黄酮类衰老细胞清除剂 |
Zhang, L. J. |
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N/A |
Development of novel flavonoid senolytics through phenotypic drug screening and drug design |
| 在受控流动条件下对芯片器官进行系统标准化：以Caki-1和A549细胞系为例的应用案例 |
Balsa-Diaz, A. |
PDF |
N/A |
Systematic standardization of organ-on-a-chip under controlled flow conditions: use case with Caki-1 and A549 cell lines |