| 影响单基因树年代测定准确性和精确性的因素 |
Louvel, G. |
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N/A |
Factors influencing the accuracy and precision in dating single gene trees |
| 性染色体基因表达与雌性斑胸草雀在激素调控后的鸣叫学习相关 |
Davenport, M. |
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N/A |
Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches |
| 系统发育状态依赖性多样化模型（SSEs）的隐藏模型空间：一致性、挑战与机遇 |
Tarasov, S. |
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N/A |
The Hidden Model Space of Phylogenetic State-Dependent Diversification Models (SSEs): Congruence, Challenges, and Opportunities |
| 脑细胞外基质中的不可移动阴离子成分取代了细胞外氯离子 |
Normoyle, K. P. |
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N/A |
Displacement of extracellular chloride by immobile anionic constituents of the brain's extracellular matrix |
| BiATNovo：一种基于注意力机制的双向从头测序框架，用于数据非依赖性采集质谱分析 |
Yang, S. |
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N/A |
BiATNovo: An Attention-based Bidirectional De Novo Sequencing Framework for Data-Independent-Acquisition Mass Spectrometry |
| 从贝叶斯到达尔文：基于采样的贝叶斯推断作为进化搜索的一种前适应 |
Csillag, M. |
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N/A |
From Bayes to Darwin: evolutionary search as an exaptation from sampling-based Bayesian inference |
| 听觉皮层解剖结构反映了多语言的语音经验。 |
Kepinska, O. |
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N/A |
Auditory cortex anatomy reflects multilingual phonological experience |
| I-SVVS：整合随机变分变量选择方法，用于探索多组学微生物组数据的联合模式 |
Dang, T. |
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N/A |
I-SVVS: Integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data |
| HSF-DREB-MYB转录调控模块调控香蕉（Musa acuminata）中黄酮醇生物合成及黄酮类B环羟基化 |
Naik, J. |
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N/A |
The HSF-DREB-MYB transcriptional regulatory module regulates flavonol biosynthesis and flavonoid B-ring hydroxylation in banana(Musa acuminata) |
| Extramacrochaetae 通过非凋亡性胱天蛋白酶活性调节果蝇眼中的 Notch 信号传导 |
Baker, N. E. |
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N/A |
Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity |
| 可视化液-液相变 |
Sahoo, B. R. |
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N/A |
Visualizing liquid-liquid phase transitions |
| 过度表达人类RAMP1的小鼠对治疗运动敏感性的偏头痛疗法具有抵抗力。 |
Rahman, S. M. |
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N/A |
Human RAMP1 overexpressing mice are resistant to migraine therapies for motion sensitivity |
| 片段扩增的转录组和蛋白质组学影响 |
Fritts, R. K. |
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N/A |
The transcriptomic and proteomic ramifications of segmental amplification |
| 各方面都极端：由于种群数量持续偏小，雪豹的遗传多样性极低 |
Solari, K. A. |
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N/A |
Extreme in Every Way: Exceedingly Low Genetic Diversity in Snow Leopards Due to Persistently Small Population Size |
| 一氧化氮调节小鼠视网膜神经节细胞中的一部分对比度抑制作用 |
Gonschorek, D. |
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N/A |
Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells |
| 胚胎来源的脑内常驻巨噬细胞维持睡眠-觉醒回路 |
Seifinejad, A. |
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N/A |
Embryo-derived brain-resident macrophages sustain sleep-wake circuits |
| 地理分布广泛且新型的嗜血支原体和巴尔通体在墨西哥无尾蝙蝠及其同域分布的北美蝙蝠物种中的发现 |
Becker, D. |
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N/A |
Geographically widespread and novel hemotropic mycoplasmas and bartonellae in Mexican free-tailed bats and sympatric North American bat species |
| 基于多种减毒机制的减毒活SARS-CoV-2疫苗候选株的免疫原性和安全性 |
Suzuki, M. |
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N/A |
Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms |
| 抑制NFAT会促进人体组织驻留型子宫自然杀伤细胞的丧失，并伴随妊娠并发症的发生。 |
Asiimwe, R. |
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N/A |
Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans |
| Smad4和TGF-β1依赖的基因表达生物标志物在条件性肠道腺瘤、类器官和结直肠癌中的研究。 |
Surakhy, M. |
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N/A |
Smad4 and TGF-β1 dependent gene expression biomarkers in conditional intestinal adenoma, organoids and colorectal cancer. |
| 脂氧素B4和眼压对视神经中疾病相关小胶质细胞的调控 |
Maurya, S. |
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N/A |
Regulation of Diseases-Associated Microglia in the Optic Nerve by Lipoxin B4 and Ocular Hypertension |
| 人类气道巨噬细胞在IFN-γ的作用下发生代谢重编程，导致依赖糖酵解的功能可塑性。 |
Cox, D. J. |
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N/A |
Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity. |
| Sir2和Fun30通过Mcm解旋酶定位和核小体占据来调节核糖体DNA复制时序 |
Lichauco, C. |
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N/A |
Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy |
| Tcf21作为创始转录因子在指定Foxd1细胞为近球小管细胞谱系中的作用 |
Anjum, H. |
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N/A |
Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage |
| 启用微观真实大脑的电场模型 |
Qi, Z. |
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N/A |
Enabling Electric Field Model of Microscopically Realistic Brain |
| 快速且灵敏的蛋白质复合物比对工具：Foldseek-Multimer |
Kim, W. |
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N/A |
Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer |
| Panx1敲除通过改变AMPK/mTOR信号通路和突触组成加剧了斑马鱼中的氧化应激和细胞死亡 |
Zoidl, G. S. O. |
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N/A |
Panx1 Ablation Aggravates Oxidative Stress and Cell Death by Altering AMPK/mTOR signaling Pathways and the Composition of Synapses in the Zebrafish |
| 开放通道液滴微流控平台用于被动生成人类精子微滴 |
Nicholson, T. M. |
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N/A |
Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets |
| 揭示从序列中得出的蛋白质结构域中的保守别构热点 |
Hacisuleyman, A. |
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N/A |
Unveiling Conserved Allosteric Hot Spots in Protein Domains from Sequences |
| 古代基因组揭示了公元9至10世纪在喀尔巴阡盆地发生的阿瓦尔-匈牙利转变 |
Gerber, D. |
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N/A |
Ancient genomes reveal Avar-Hungarian transformations in the 9-10th centuries CE in the Carpathian Basin |
| 生活在金属污染河流中的褐鳟的基因组特征及对金属耐受性的转录反应 |
Paris, J. R. |
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N/A |
The genomic signature and transcriptional response of metal tolerance in brown trout inhabiting metal-polluted rivers |
| 建模进化谱系的速率并预测扩散模式 |
Bastide, P. |
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N/A |
Modeling the velocity of evolving lineages and predicting dispersal patterns |
| 内侧纹状体核中GABA/谷氨酸共传递神经元对选择方向和结果的混合表征 |
Locantore, J. |
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N/A |
Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleus |
| 综合网络分析揭示阿尔茨海默病中Aβ-Tau相互作用的新型调节因子 |
Kitani, A. |
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N/A |
Integrative Network Analysis Reveals Novel Moderators of Aβ-Tau Interaction in Alzheimer's Disease |
| 细胞单层中的信息传递：一项数值研究 |
Nałecz-Jawecki, P. |
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N/A |
Information transmission in a cell monolayer: A numerical study |
| 在发育过程中处于复杂声学环境中的斑胸草雀，其听觉感知和编码效率得到了增强。 |
Moseley, S. M. |
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N/A |
A complex acoustical environment during development enhances auditory perception and coding efficiency in the zebra finch |
| 前馈网络中信号汇聚和发散的尖峰编码的时间分辨率 |
Mobille, Z. |
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N/A |
Temporal resolution of spike coding in feedforward networks with signal convergence and divergence |
| 提高中欧和东欧家庭花园的生物多样性需要区域性的策略 |
Varga-Szilay, Z. |
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N/A |
Improving biodiversity in Central and Eastern European domestic gardens needs regionally scaled strategies |
| Biom3d，一个模块化的框架，用于托管和开发3D分割方法 |
Mougeot, G. |
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N/A |
Biom3d, a modular framework to host and develop 3D segmentation methods |
| 鉴定B群链球菌中的乙二醛酶A及其对甲基乙二醛耐受性和毒力的贡献 |
Akbari, M. S. |
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N/A |
Identification of Glyoxalase A in Group B Streptococcus and its contribution to methylglyoxal tolerance and virulence |
| 肥胖中铁死亡的调控：饮食限制和运动的肌肉类型特异性效应 |
Ji, F. |
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N/A |
Regulation of Ferroptosis in Obesity: Muscle Type-Specific Effects of Dietary Restriction and Exercise |
| 虚弱综合征对骨骼肌组织学的影响：运动的预防作用 |
Ji, F. |
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N/A |
The Impact of Frailty Syndrome on Skeletal Muscle Histology: Preventive Effects of Exercise |
| ADAM通过与大型蛋白质复合物相互作用，调控组蛋白修饰、基因表达和剪接过程。 |
Pandey, A. |
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N/A |
ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing. |
| 棉花纤维细胞壁性质的发育变异性与重要的农艺性状相关联 |
Wilson, M. C. |
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N/A |
Developmental variability in cotton fiber cell wall properties linked to important agronomic traits |
| 通过BONCAT和基于点击化学的新合成蛋白质富集技术追踪微生物群落中的活跃成员 |
Hellwig, P. |
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N/A |
Tracing active members in microbial communities by BONCAT and click chemistry-based enrichment of newly synthesised proteins |
| 基于秀丽隐杆线虫毒性测试的自动化微流控平台 |
Wu, J. |
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N/A |
An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans |
| 乙醇培养物中Cyberlindnera jadinii的生理定量与生物量组成 |
Vieira-Lara, M. A. |
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N/A |
Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures |
| 通过整合机制建模和深度学习发现可解释的模式规则 |
Lu, J. |
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N/A |
Discovery of interpretable patterning rules by integrating mechanistic modeling and deep learning |
| 特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了编码不同运动障碍行为的机制。 |
Alcacer, C. |
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N/A |
Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering |
| 作物育种中基因组预测集成方法预测性能的改进 |
Tomura, S. |
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N/A |
Improvements in Prediction Performance of Ensemble Approaches for Genomic Prediction in Crop Breeding |
| 通过蛋白质组学检测ESKAPE病原体的抗生素抗性并同时鉴定其物种 |
Blumenscheit, C. |
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N/A |
Antibiotic resistance detection and concomitant species identification of ESKAPE pathogens by proteomics |
| 在小鼠齿状回中，5-HT7受体的激活并不影响穿通路径突触处的θ脉冲诱导的可塑性。 |
Siwiec, M. |
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N/A |
Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse |
| 基于深度学习的基因扰动效应预测尚未超越简单的线性方法。 |
Ahlmann-Eltze, C. |
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N/A |
Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods |
| CAR Treg与抗CD154协同作用介导感染性耐受，以决定心脏移植结果。 |
Durgam, S. S. |
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N/A |
CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes. |
| 催产素受体调控草原田鼠配对结合和发育的不同方面 |
Sharma, R. |
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N/A |
Oxytocin receptor controls distinct components of pair bonding and development in prairie voles |
| 编码于自我扩增RNA中的广谱免疫抑制能够实现持续、可逆且非免疫刺激性的表达。 |
Lim, T. K. Y. |
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N/A |
Broad-spectrum immune suppression encoded in self-amplifying RNA enables sustained, reversible, and non-immunostimulatory expression |
| 区间删失对生物高通量筛选中数据准确性和机器学习性能的影响 |
Doffini, V. |
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N/A |
Impact of Interval Censoring on Data Accuracy and Machine Learning Performance in Biological High-Throughput Screening |
| 甲基组揭示了两种植物物种种群中最近的进化变化 |
Korfmann, K. |
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N/A |
Methylomes reveal recent evolutionary changes in populations of two plant species |
| 单细胞核测序揭示肾上腺皮质癌中的复制压力 |
Popova, L. V. |
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N/A |
Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma |
| 高血压中的肠道微生物代谢通量紊乱 |
Wenkai, L. |
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N/A |
Gut microbial metabolic flux disorder in hypertension |
| 甲虫-真菌互利共生体系中共生真菌的基因组多样化 |
Huang, Y.-T. |
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N/A |
Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis |
| CXCL10/CXCR3信号传导引发神经衰老及认知障碍 |
Patel, M. |
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N/A |
CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments |
| 艺术的隐秘拓扑：一扇通往人类感知的大门 |
Dmitruk, E. |
PDF |
N/A |
Art's Hidden Topology: A window into human perception |
| 人类谱系的深度合并历史 |
Cousins, T. |
PDF |
N/A |
Deep coalescent history of the hominin lineage |
| 年龄相关的大脑成熟与年轻化：丰富环境中神经3D染色质互作组的演变 |
Gancedo-Verdejo, J. |
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N/A |
Age-Dependent Maturation and Rejuvenation of the Neural 3D Chromatin Interactome in Enriched Environments |
| 在早更新世至中更新世过渡期间，人类经历了严重瓶颈的证据不足。 |
Cousins, T. |
PDF |
N/A |
Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition |
| 四刺鱼（Apeltes quadracus）具有XY性染色体系统，其X和Y染色体上均存在多态性倒位。 |
Liu, Z. |
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N/A |
The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes |
| 一种I型3' UTR衍生的sRNA参与了金黄色葡萄球菌中的血红素代谢和毒力 |
Silard, C. |
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N/A |
A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus |
| 可分离的默认模式网络连接模式在精神病风险中导致不同的症状 |
Ajunwa, C. C. |
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N/A |
Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk |
| 身体游走揭示了思维的具身维度，具有独特的影响和神经特征。 |
Banellis, L. |
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N/A |
Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures |
| 斑马鱼中个体保守神经元微外显子和其主调控因子的表型影响 |
Lopez-Blanch, L. |
PDF |
N/A |
Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish |
| 具有多种中间神经元类型的皮层网络在预测编码过程中产生振荡模式 |
Lee, K. |
PDF |
N/A |
Cortical networks with multiple interneuron types generate oscillatory patterns during predictive coding |
| 运动补偿而非感觉误差调节自然言语生成中的序列依赖性 |
Lu, Y. |
PDF |
N/A |
Motor compensations, not sensory errors, regulate serial dependence in naturalistic speech production |
| 小鼠少突胶质前体细胞在整个生命周期中的转录组特征 |
Heo, D. |
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N/A |
Transcriptional profiles of murine oligodendrocyte precursor cells across the lifespan |
| 优势逆转保护了在时间变化环境中具有较大效应的抗性多态性 |
Karageorgi, M. |
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N/A |
Dominance reversal protects large-effect resistance polymorphisms in temporally varying environments |
| 蚂蚁导航行为的比较研究 |
Shen, X. |
PDF |
N/A |
A comparative study of navigation behaviours in ants |
| 昆虫生物群图集数据：瑞典和马达加斯加陆生节肢动物的元条形码调查 |
Miraldo, A. |
PDF |
N/A |
Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar |
| 解析南美洲沿海洛马斯植物多样性的逆纬度梯度：环境和地理因素的影响 |
Gonzales, F. N. |
PDF |
N/A |
Unraveling the inverse latitudinal gradient: Environmental and geographic influences on plant diversity in South American coastal lomas |
| 气候、天气和地理因素共同塑造了北美西部种子质量的变化和下降趋势。 |
Lenzo, L. |
PDF |
N/A |
Climate, weather, and geography shape seed mass variation and decline across western North America |
| 发展新技术以保护生态系统：采用适应性管理进行规划 |
Pascal, L. V. |
PDF |
N/A |
Developing new technologies to protect ecosystems: planning with adaptive management |
| 改进入侵蓝蟹（Callinectes sapidus）的监测：结合环境DNA和公民观察 |
Delrieu-Trottin, E. |
PDF |
N/A |
Improving the monitoring of the invasive Blue Crab (Callinectes sapidus): combining environmental DNA and citizen observations |
| 腺嘌呤DNA甲基化与转录相关，在真核生物中广泛存在。 |
Romero Charria, P. |
PDF |
N/A |
Adenine DNA methylation associated to transcription is widespread across eukaryotes |
| 通过花粉间接从头再生实现药用型大麻（Cannabis sativa L.）的双单倍体发育。 |
Tonolo, F. |
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N/A |
Double haploid development in drug-type Cannabis sativa L. through microspore indirect de-novo plant regeneration. |
| 基于受体的蛋白质结合在天鹅绒虫粘液的超分子网络中 |
Hu, Z. |
PDF |
N/A |
Receptor-based protein binding in the supramolecular network of velvet worm slime |
| Muscle-3D：可扩展的多重蛋白质结构比对 |
Edgar, R. C. |
PDF |
N/A |
Muscle-3D: scalable multiple protein structure alignment |
| 经典的统计方法在识别乳腺癌患者生存的新靶点方面具有强大的作用。 |
Insawang, B. |
PDF |
N/A |
Classical statistical methods are powerful for the identification of novel targets for the survival of breast cancer patients |
| 解决脊椎动物古生物学中的“个体发育问题” |
Napoli, J. |
PDF |
N/A |
Resolving the "Ontogeny Problem" in Vertebrate Paleontology |
| 眼见不为实？改善科学博士生导师关系的视角获取干预的混合效应 |
Tuma, T. T. |
PDF |
N/A |
Seeing isn't believing? Mixed effects of a perspective-getting intervention to improve mentoring relationships for science doctoral students |
| Nematostella Wnt/β-catenin破坏复合体为理解主要后生动物信号转导途径调控的进化提供了见解。 |
Sun, H. |
PDF |
N/A |
The Nematostella Wnt/β-catenin destruction complex provides insight into the evolution of the regulation of a major metazoan signal transduction pathway |
| 在喀斯特天窗中的长期杂交揭示了洞穴鱼类眼睛丧失的遗传基础 |
Kellermeyer, R. |
PDF |
N/A |
Long-term hybridization in a karst window reveals the genetic basis of eye loss in cavefish |
| 五个甜瓜（Cucumis melo L.）品种Ananas、Canton、PI 414723、Vedrantais和Zhimali的核与细胞器基因组组装，这些品种属于不同的植物分类群。 |
Belinchon-Moreno, J. |
PDF |
N/A |
Nuclear and organelle genome assemblies of five Cucumis melo L. accessions, Ananas, Canton, PI 414723, Vedrantais and Zhimali, belonging to diverse botanical groups |
| 前列腺癌中的miRNA生物标志物：利用机器学习提高诊断准确性 |
Singh, S. |
PDF |
N/A |
miRNA Biomarkers in Prostate Cancer: Leveraging Machine Learning for Improved Diagnostic Accuracy |
| 自动催化组装的一种嵌合氨基酸-RNA合成酶核酶 |
Radakovic, A. |
PDF |
N/A |
Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme |
| 开发自主神经系统多尺度神经连接知识库 |
Imam, F. T. |
PDF |
N/A |
Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System |
| APOBEC3A通过改变上皮间质转化驱动卵巢癌的转移 |
Devenport, J. M. |
PDF |
N/A |
APOBEC3A drives metastasis of ovarian cancer by altering epithelial-to-mesenchymal transition |
| 通过比较基因组学和西部合鸣蛙的新染色体水平基因组，揭示了两栖类的宏观共线性、“叛逆”基因和新性连锁区域 |
Chen, Y. |
PDF |
N/A |
Insights on macrosynteny, 'rebel' genes, and a new sex-linked region in anurans from comparative genomics and a new chromosome-level genome for the western chorus frog |
| 阿尔茨海默病人类大脑中长非编码RNA的空间表达 |
Ng, B. |
PDF |
N/A |
Spatial Expression of Long Non-Coding RNAs in Human Brains of Alzheimer's Disease |
| 数字降噪处理对皮层下言语编码的影响及其与行为结果的关系 |
Kim, S. |
PDF |
N/A |
Effect of digital noise-reduction processing on subcortical speech encoding and relationship to behavioral outcomes |
| 时间上下文对多时间尺度视觉的影响 |
Lee, K. |
PDF |
N/A |
The influence of temporal context on vision over multiple time scales |
| 阿尔茨海默病患者的脑提取物在血管化神经免疫类器官中诱导多种病理，用于疾病建模和药物发现 |
Ji, Y. |
PDF |
N/A |
Alzheimer's Disease Patient Brain Extracts Induce Multiple Pathologies in Vascularized Neuroimmune Organoids for Disease Modeling and Drug Discovery |
| 左乙拉西坦通过SV2a依赖性调节阿尔茨海默病模型中App加工过程，从而抑制Aβ42的产生。 |
Rao, N. R. |
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N/A |
Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer's disease models |
| 体育活动在缓解与年龄相关的步态神经肌肉控制变化中的作用 |
Nunez-Lisboa, M. A. |
PDF |
N/A |
The Role of Physical Activity in Mitigating Age-Related Changes in the Neuromuscular Control of Gait |
| NAD+及EVA1-C依赖的神经功能缺陷逆转，是通过在tau病动物模型中差异性选择性RNA剪接介导的。 |
Ai, R. |
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N/A |
NAD+ - and EVA1-C-dependent reversal of neurological deficits is mediated by differential alternative RNA splicing in tauopathic animal models |
| 跨眼跳空间更新和错位定位的电路模型 |
Wang, X. |
PDF |
N/A |
A circuit model for transsaccadic space updating and mislocalization |
| 听觉皮层中的正交频谱和时间包络表示 |
Takahashi, K. |
PDF |
N/A |
Orthogonal spectral and temporal envelope representation in auditory cortex |
| 急性有氧运动增强活跃个体的联想学习能力，但对久坐个体无此效果。 |
Gultig, K. D. |
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N/A |
Acute Aerobic Exercise Enhances Associative Learning in Active but not Sedentary Individuals |
| 多模态成像结合单突触分析中的突触组成、活性、mRNA翻译及动态变化 |
Falkovich, R. |
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N/A |
Synaptic composition, activity, mRNA translation and dynamics in combined single-synapse profiling using multimodal imaging |
| 化学感觉对斑马鱼幼体眼部与身体协调的调控 |
Sy, S. K. H. |
PDF |
N/A |
Chemosensory modulation of eye-body coordination in larval zebrafish |
| 恢复与多发性硬化症相关的肠道吲哚代谢物失衡可促进髓鞘再生并抑制神经炎症 |
Jank, L. |
PDF |
N/A |
Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation |
| 神经场理论作为一种框架，用于建模和理解大脑中的意识状态 |
Polyakov, D. |
PDF |
N/A |
Neural field theory as a framework for modeling and understanding consciousness states in the brain |
| 慢波睡眠与老年人的伏隔核体积有关 |
Ban, K. |
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N/A |
Slow-wave sleep is associated with nucleus accumbens volume in elderly adults |
| 在普通狨猴中进行的微创皮层脑电图（ECoG）记录 |
Spadacenta, S. |
PDF |
N/A |
Minimally invasive electrocorticography (ECoG) recording in common marmosets |
| 绘制成年期全生命周期的海马体-小脑功能连接图 |
Apasamy, K. |
PDF |
N/A |
Mapping hippocampal-cerebellar functional connectivity across the adult lifespan |
| 由局部抑制性回路调节的皮层再激活介导记忆巩固 |
Lensjo, K. K. |
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N/A |
Cortical Reactivations Modulated by Local InhibitoryCircuits Mediate Memory Consolidation |
| 前下丘脑回路调控应激易感性 |
Pennington, Z. T. |
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N/A |
An anterior hypothalamic circuit gates stress vulnerability |
| 屏状核对于维持工作记忆信息至关重要。 |
Bhattacharjee, A. S. |
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N/A |
The claustrum is critical for maintaining working memory information |
| 利用个体特异的几何和连接组特征模式重建皮层功能图谱 |
Olsen, A. S. |
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N/A |
On reconstruction of cortical functional maps using subject-specific geometric and connectome eigenmodes |
| fNIRS研究中的包容性：量化头发和皮肤特征对信号质量的影响，并提供实用的改进建议 |
Yücel, M. A. |
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N/A |
Inclusivity in fNIRS Studies: Quantifying the Impact of Hair and Skin Characteristics on Signal Quality with Practical Recommendations for Improvement |
| 自闭症患者5-40岁期间的异常语言网络动态 |
Hu, Z. |
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N/A |
The aberrant language network dynamics in autism ages 5-40 years |
| 在搜索过程中，通过观察工作记忆来验证潜在目标 |
Wang, S. |
PDF |
N/A |
Looking into working memory to verify potential targets during search |
| 早期社会隔离应激诱导的自然行为变化与雌性大鼠成年期暴食行为相关 |
Simon, T. B. |
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N/A |
Shifts in Naturalistic Behaviors Induced by Early Social Isolation Stress are Associated with Adult Binge-like Eating in Female Rats |
| 人脑新皮层中快速放电中间神经元的动作电位发放阈值降低的机制与目的 |
Bakos, E. |
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N/A |
Mechanisms and purpose of lowered action potential firing threshold in fast-spiking interneurons in the human neocortex |
| 儿茶酚胺减少选择历史偏差 |
de Gee, J. W. |
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N/A |
Catecholamines reduce choice history biases |
| 节奏与背景（RnB）：睡眠记录的光谱分析 |
Dube, J. |
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N/A |
Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings |
| 探索记忆回放在目标记忆再激活和鸟鸣发育中的作用：来自互补学习系统计算模型的见解 |
Lu, Y. |
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N/A |
Exploring the roles of memory replay in targeted memory reactivation and birdsong development: Insights from computational models of complementary learning systems |
| Foxn3是调控发育中鼠视网膜纤毛基因的转录网络的一部分。 |
Zhang, H. |
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N/A |
Foxn3 is part of a transcriptional network that regulates cilia genes in the developing mouse retina |
| Frem2敲除小鼠表现出Fraser综合征的表型，并因双侧肾发育不全而导致新生期死亡。 |
Simikyan, R. G. |
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N/A |
Frem2 Knockout Mice Exhibit Fraser Syndrome Phenotypes and Neonatal Lethality Due to Bilateral Renal Agenesis |
| 制作神经机器人与嵌合体栉水母 |
Moroz, L. L. |
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N/A |
Making Neurobots and Chimerical Ctenophores |
| 在捕食下的椋鸟群聚 |
Papadopoulou, M. |
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N/A |
Starling murmurations under predation |
| 觅食关联与合作繁殖鸟类中的帮助行为有关 |
Ferreira, A. C. |
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N/A |
Foraging associations are related with helping interactions in a cooperatively breeding bird |
| 我该留下还是离开？带有时间折扣的广义边际价值理论 |
Zylberberg, J. |
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N/A |
Should I stay or should I go? Generalized marginal value theorem with temporal discounting |
| 温度影响果蝇同种和异种交配率 |
Rader, J. A. |
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N/A |
Temperature affects conspecific and heterospecific mating rates in Drosophila |
| 探究生物质前体合成作为微生物适应非适应碳源的关键因素 |
Cai, J. |
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N/A |
Probing Biomass Precursor Synthesis as a Key Factor in Microbial Adaptation to Unadapted Carbon Sources |
| FoldMark：通过水印技术保护蛋白质生成模型 |
ZHANG, Z. |
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N/A |
FoldMark: Protecting Protein Generative Models with Watermarking |
| 利用幂后验进行突变特征的稳健发现 |
Xue, C. |
PDF |
N/A |
Robust discovery of mutational signatures using power posteriors |
| scGenePT：语言模型是否足以模拟单细胞扰动？ |
Istrate, A.-M. |
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N/A |
scGenePT: Is language all you need for modeling single-cell perturbations? |
| 使用突变特异性小分子激活p53Y220C |
Zhu, X. |
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N/A |
Activating p53Y220C with a Mutant-Specific Small Molecule |
| 导致远端肾小管酸中毒的SLC4A1突变会改变胞质pH值和细胞自噬 |
Essuman, G. |
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N/A |
SLC4A1 MUTATIONS THAT CAUSE DISTAL RENAL TUBULAR ACIDOSIS ALTER CYTOPLASMIC PH AND CELLULAR AUTOPHAGY |
| 小脑炎症与神经退行性变在新型的脊髓小脑共济失调13型小鼠模型中的关联 |
Yin, J. |
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N/A |
Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model |
| 青少年多巴胺神经元中Grin2a的减少会导致异常的显著性和相关精神病性症状 |
Kielhold, M. L. |
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N/A |
Reductions of Grin2a in adolescent dopamine neurons confers aberrant salience and related psychosis phenotype |
| 轻柔的曲调调教出一种新奇的长期威胁回避行为 |
Aranda, M. L. |
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N/A |
Light tunes a novel long-term threat avoidance behavior |
| LGI1自身抗体对人类CA3锥体神经元的功能影响 |
Monni, L. |
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N/A |
The functional impact of LGI1 autoantibodies on human CA3 pyramidal neurons |
| 减少叶酸载体1（RFC1/Slc19a1）抑制加剧成年小鼠实验性缺血性卒中中的血脑屏障破坏 |
Gurler, G. |
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N/A |
Reduced Folate Carrier 1 (RFC1/Slc19a1) Suppression Exacerbates Blood-Brain Barrier Breakdown in Experimental Ischemic Stroke in Adult Mice |
| 微扫视强烈地调节但并不引起空间注意的N2pc脑电标记 |
Liu, B. |
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N/A |
Microsaccades strongly modulate but do not cause the N2pc EEG marker of spatial attention |
| 酒精依赖小鼠中丘脑背内侧核的遗传和功能适应以及酒精偏向性信号传导 |
Martin, J. C. |
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N/A |
Genetic and functional adaptations and alcohol-biased signaling in the mediodorsal thalamus of alcohol dependent mice |
| 基于结构的莱姆病亚单位疫苗设计机制性见解 |
Brangulis, K. |
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N/A |
Mechanistic insights into structure-based design of a Lyme disease subunit vaccine |
| 被边缘案例所迷惑：当前方法能否通过机器学习实现对T细胞特异性的准确预测？ |
Culka, M. |
PDF |
N/A |
Tricked by Edge Cases: Can Current Approaches Lead to Accurate Prediction of T-Cell Specificity with Machine Learning? |
| 小鼠植入前发育过程中mRNA翻译的时空动态和选择性 |
Jiang, Z. |
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N/A |
Spatiotemporal dynamics and selectivity of mRNA translation during mouse pre-implantation development |
| 调整选择压力的空间分布以抑制抗性的出现 |
Tunstall, T. |
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N/A |
Tuning Spatial Distributions of Selection Pressure to Suppress Emergence of Resistance |
| 粉蚧的多样化是由新共生体的获得引发的，随后在寄主植物上发生了适应性辐射。 |
Choi, J. |
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N/A |
The diversification of mealybugs was triggered by new symbiont acquisitions and followed by adaptive radiations on host plants |
| 内皮细胞的硬度和类型驱动了生物力学诱导的跨细胞孔隙的形成 |
Siadat, S. M. |
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N/A |
Endothelial cell stiffness and type drive the formation of biomechanically-induced transcellular pores |
| Genular：一个通过单细胞基因表达和多领域生物数据定义细胞身份和功能的综合平台 |
Tomic, I. |
PDF |
N/A |
Genular: An Integrated Platform for Defining Cellular Identity and Function through Single-Cell Gene Expression and Multi-Domain Biological Data |
| DNA挂架：表面自由单分子印迹平台 |
Seol, J. |
PDF |
N/A |
DNA Hanger: Surface Free Single-Molecule Blotting Platform |
| 单细胞蛋白质组学和转录组学表征揭示了耐药性前列腺癌细胞的分子特征与形态变化之间的关联 |
Woo, J. |
PDF |
N/A |
Single-Cell Proteomic and Transcriptomic Characterization of Drug-Resistant Prostate Cancer Cells Reveals Molecular Signatures Associated with Morphological Changes |
| SPP1+肿瘤相关巨噬细胞通过与肿瘤微环境的相互作用诱导鼻咽癌的放疗抵抗 |
Zhang, W. |
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N/A |
SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironment |
| 线粒体伴侣蛋白TRAP1的点突变会影响其功能和促肿瘤活性。 |
Laquatra, C. |
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N/A |
Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity. |
| 整合应激反应途径在肺癌中对多个免疫检查点的协调性转录调控 |
Thomas-Jardin, S. |
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N/A |
Coordinated translational control of multiple immune checkpoints by the integrated stress response pathway in lung cancer |
| 膳食纤维调节巨噬细胞活性在结直肠癌结肠细胞-微生物相互作用微流控模型中 |
Penarete-Acosta, D. |
PDF |
N/A |
Dietary Fiber Modulates Macrophage Activity in a Microfluidic Model of Colonocyte-Microbiota Interactions in Colorectal Cancer |
| 激素治疗前局部前列腺癌中上皮功能状态和成纤维细胞表型的分析 |
Apostolov, E. |
PDF |
N/A |
Profiling of epithelial functional states and fibroblast phenotypes in hormone therapy-naive localised prostate cancer |
| 热中性环境对小鼠MASLD严重程度、肝基因表达及β3-肾上腺素能刺激下BAT激活的影响 |
Martin, C. M. |
PDF |
N/A |
Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during beta3-adrenergic stimulation in mice |
| 改变AP-1、RUNX和EGR的染色质动力学驱动纤维化肺病 |
Valenzi, E. |
PDF |
N/A |
Altered AP-1, RUNX, and EGR chromatin dynamics drive fibrotic lung disease |
| 抗PTHrP阻断限制了CD8+ T细胞在抗癌免疫疗法中的衰竭 |
Moes, B. |
PDF |
N/A |
Anti-PTHrP blockade limits CD8+ T-cell exhaustion in anti-cancer immunotherapy |
| 通过抗体语言模型优先掩盖非模板区域进行聚焦学习 |
Ng, K. |
PDF |
N/A |
Focused learning by antibody language models using preferential masking of non-templated regions |
| 糖尿病-结核病共病特征为Ⅱ型干扰素减少和Th17反应增强。 |
Chaudhary, S. |
PDF |
N/A |
Diabetes-Tuberculosis Comorbidity Characterized by Reduced Type-II Interferon and Elevated Th17 Responses. |
| 破坏G3BP1应激颗粒宿主蛋白与核衣壳（NTD-N）蛋白之间的分子相互作用会阻碍SARS-CoV-2病毒的复制。 |
Dhaka, P. |
PDF |
N/A |
Disruption of molecular interactions between G3BP1 stress granule host protein and nucleocapsid (NTD-N) protein impedes SARS-CoV-2 virus replication |
| Oatk：一种用于复杂植物细胞器基因组从头组装的工具 |
Zhou, C. |
PDF |
N/A |
Oatk: a de novo assembly tool for complex plant organelle genomes |
| PhenoScreen：一种基于双空间对比学习框架的表型筛选方法，通过将化学扰动与细胞形态联系起来 |
Wang, S. |
PDF |
N/A |
PhenoScreen: A Dual-Space Contrastive Learning Framework-based Phenotypic Screening Method by Linking Chemical Perturbations to Cellular Morphology |
| 内在无序的Qβ衣壳蛋白与含发夹RNA形成多相RNP颗粒 |
Granik, N. |
PDF |
N/A |
Formation of polyphasic RNP granules by intrinsically disordered Qβ coat proteins and hairpin-containing RNA |
| 多巴胺调控秀丽隐杆线虫对锰诱导的多巴胺能神经毒性的敏感性。 |
Raj, V. |
PDF |
N/A |
Dopamine controls the Sensitivity to Manganese induced Dopaminergic neurotoxicity in Caenorhabditis elegans |
| 棕色脂肪组织产热节律是由视交叉上核驱动的，与脂肪细胞时钟无关。 |
Paschos, G. K. |
PDF |
N/A |
Brown adipose tissue thermogenesis rhythms are driven by the SCN independent of adipocyte clocks |
| 通过免疫信息学分析进行的多表位疫苗的计算机设计，用于对抗蜱传脑炎病毒 |
Wang, B. |
PDF |
N/A |
In silico design of a multi-epitope vaccine against tick-borne encephalitis virus via immunoinformatic analysis |
| 对来自全球多源的克雷伯氏菌变种菌株进行基因组分析，揭示了与人类感染相关的适应性特征。 |
Wang, J. |
PDF |
N/A |
Genome Analyses of A Worldwide Multisource Collection of Klebsiella variicola Reveal Adaptation Relevant for Human Infection |
| 剪接因子激酶，即SR蛋白激酶1（SRPK1），对于人乳头瘤病毒生命周期的后期事件至关重要。 |
Faizo, A. A. A. |
PDF |
N/A |
The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle. |
| CRISPR技术对基因表达的调控，决定了微生物甲烷的同位素组成。 |
Gropp, J. |
PDF |
N/A |
CRISPR-enabled control of gene expression sets the isotopic composition of microbial methane |
| Tad菌毛ATP酶CpaF中的协调构象变化促进了催化旋转机制 |
Yen, I. Y. |
PDF |
N/A |
Coordinated conformational changes in the Tad pilus ATPase CpaF facilitate a rotary mechanism of catalysis |
| 复杂系统建模揭示，草酸盐稳态是由多种草酸盐降解细菌驱动的。 |
Mukherjee, S. D. |
PDF |
N/A |
Complex system modelling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteria |
| 在生命周期中，牛奶草虫Oncopeltus fasciatus的种内微生物群动态变化 |
Larner, W. |
PDF |
N/A |
Intraspecific microbiome dynamics across the life cycle of the milkweed bug Oncopeltus fasciatus |
| 通过哺乳动物乙型肝炎病毒X蛋白实现的保守但差异化的Smc5/6复合物降解 |
Shofa, M. |
PDF |
N/A |
Conserved yet Divergent Smc5/6 Complex Degradation by Mammalian Hepatitis B Virus X Protein |
| 通过哺乳动物乙型肝炎病毒X蛋白实现的保守但分化的Smc5/6复合物降解 |
Shofa, M. |
PDF |
N/A |
Conserved yet Divergent Smc5/6 Complex Degradation by Mammalian Hepatitis B Virus X Proteins |
| 伯氏疏螺旋体在培养的静止期会失去重要的遗传元件和细胞增殖潜力，但在蜱虫媒介中则不会。 |
Zhang, J. |
PDF |
N/A |
Borrelia burgdorferi loses essential genetic elements and cell proliferative potential during stationary phase in culture but not in the tick vector. |
| 通过增加槲皮素（一种黄酮类化合物）的生物利用度，诱导产生一种协同的抗肥胖效果，这一过程由一种植物乳杆菌（L. plantarum）菌株实现。 |
Kang, Y.-G. |
PDF |
N/A |
Inducing a synergistic anti-obesity effect by increasing the bioavailability of the flavonoid rutin with a L. plantarum species |
| 前列腺特异性膜受体PPAP通过FimH结合促进大肠杆菌入侵前列腺腔细胞 |
Guedes, M. |
PDF |
N/A |
Prostate-specific membrane receptor PPAP facilitates E. coli invasion of luminal prostate cells via FimH binding |
| 转录因子Sfp1与NuA4复合体在应对营养物质可利用性方面的功能性相互作用 |
Xu, K. |
PDF |
N/A |
Functional interaction between transcription factor Sfp1 and the NuA4 complex in response to nutrient availability |
| 一种从纯化到冻干递送的环状RNA治疗完整方案，采用新型可离子化脂质 |
Broset, E. |
PDF |
N/A |
A complete approach for circRNA therapeutics from purification to lyophilized delivery using novel ionizable lipids |
| 天然产物生物合成中假定末端酰胺化域的结构 |
Rankin, M. R. |
PDF |
N/A |
Structure of a Putative Terminal Amidation Domain in Natural Product Biosynthesis |
| 可溶性鸟苷酸环化酶（NO受体）通过其转亚硝基化活性调节内皮依赖性血管舒张。 |
Younis, W. |
PDF |
N/A |
Soluble guanylyl cyclase, the NO-receptor, regulates endothelium-dependent vascular relaxation via its transnitrosation activity. |
| 唤醒原初编辑技术：精准工程改造益生菌大肠杆菌Nissle 1917 |
Chen, P.-R. |
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N/A |
Awakening prime editing for precision engineering of probiotic Escherichia coli Nissle 1917 |
| 转录调控和位点特异性生物化学的组合效应器靶向（COMET） |
Wilson, C. M. |
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N/A |
Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry |
| 使用大型语言模型操作无细胞生物铸造厂 |
Herisson, J. |
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N/A |
Operate a Cell-Free Biofoundry using Large Language Models |
| 从微RNA表达数据中定量设计细胞类型特异性mRNA稳定性 |
Oesinghaus, L. |
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N/A |
Quantitative design of cell type-specific mRNA stability from microRNA expression data |
| 运动细菌群体中空间模式转变的机制 |
Saulnier, J.-B. |
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N/A |
The mechanism of spatial pattern transition in motile bacterial collectives |
| 跨灵长类基因组筛选包膜基因揭示内源性逆转录病毒的进化和多样性模式 |
Chabukswar, S. |
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N/A |
Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses |
| 迈向完整的噬菌体尾部纤维结构图谱。 |
Klein-Sousa, V. |
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N/A |
Towards a complete phage tail fiber structure atlas. |
| 蓝细菌辅因子非依赖型磷酸甘油酸变位酶的结构元件，介导PirC调控 |
Orthwein, T. |
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N/A |
Structural elements of cyanobacterial co-factor-independent phosphoglycerate mutase that mediate regulation by PirC |
| 铜绿假单胞菌抵抗VI型分泌系统攻击的机制 |
Tejada-Arranz, A. |
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N/A |
Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks |
| 利用鸡胚绒毛尿囊膜模型评估肿瘤定植沙门氏菌株 |
Kenney, L. J. |
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N/A |
Evaluation of Tumor-colonizing Salmonella Strains using the Chick Chorioallantoic Membrane Model |
| 单细胞代谢动力学的回溯分析可预测细菌在人体巨噬细胞中的复制 |
Drame, M. |
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N/A |
Backtracking Metabolic Dynamics in Single Cells Predicts Bacterial Replication in Human Macrophages |
| NACHO介导的五聚配体门控离子通道组装机制 |
Hooda, Y. |
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N/A |
Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels |
| 动态RNA结合与无义介导的mRNA降解因子UPF2的展开 |
Szeto, J.-Y. A. |
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N/A |
Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2 |
| 邻近相互作用组分析揭示了IRE1a经典信号通路的新调控因子 |
Le Goupil, S. |
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N/A |
Proximity Interactome analyses unveil novel regulators of IRE1a canonical signaling |
| Neuroligin 3突显了果蝇社交间隔中的性别二态性回路 |
Robinson, J. W. |
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N/A |
Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing |