| 将新的视觉类别雕刻进人类大脑 |
Iordan, C. R. |
PDF |
N/A |
Sculpting New Visual Categories into the Human Brain |
| 秀丽隐杆线虫中双链RNA的跨代运输可以限制可遗传的表观遗传变化 |
Shugarts, N. |
PDF |
N/A |
Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes |
| 沙门氏菌诱导的SIRT1和SIRT3对于维持细菌和宿主的代谢转换至关重要，以实现成功的致病过程。 |
Hajra, D. |
PDF |
N/A |
Salmonella-induced SIRT1 and SIRT3 are crucial for maintaining the metabolic switch in bacteria and host for successful pathogenesis |
| 将中风后手臂瘫痪中的移动和保持控制分开 |
Hadjiosif, A. M. |
PDF |
N/A |
Separating the control of moving and holding in post-stroke arm paresis |
| 阿米巴样细胞在软端极化的NMIIA作用下进行硬度趋向性运动。 |
Kang, C. |
PDF |
N/A |
Amoeboid cells undergo durotaxis with soft end polarized NMIIA |
| 系统性忽视与对变化过度和不足反应的神经计算基础 |
Wang, M.-C. |
PDF |
N/A |
System Neglect and the Neurocomputational Substrates for Over- and Underreactions to Change |
| 检测政权更迭：对变化过度反应和反应不足的神经计算基础 |
Wang, M.-C. |
PDF |
N/A |
Detecting Regime Shifts: Neurocomputational Substrates for Over- and Underreactions to Change |
| 上皮微侵袭与由疾病减毒肺炎球菌生物合成基因突变体引发的免疫反应 |
Weight, C. M. |
PDF |
N/A |
Epithelial microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants |
| 居留-殖民权衡与生态位分化使得大肠杆菌的多个谱系能在健康人体中共存 |
Morel-Journel, T. |
PDF |
N/A |
Residence-colonization trade-off and niche differentiation enable the coexistence of Escherichia coli phylogroups in healthy humans |
| Cell2Sentence：教授大型语言模型生物学的语言 |
Levine, D. |
PDF |
N/A |
Cell2Sentence: Teaching Large Language Models the Language of Biology |
| TgLaforin，一种葡聚糖磷酸酶，揭示了储存多糖在刚地弓形虫速殖子和缓殖子中的动态作用。 |
Murphy, R. D. |
PDF |
N/A |
TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites |
| DetectEV：一种用于评估细胞外囊泡完整性和生物活性的功能性酶学检测方法 |
Adamo, G. |
PDF |
N/A |
DetectEV: a functional enzymatic assays to assess integrity and bioactivity of extracellular vesicles |
| 通过水平基因转移获得的基因在Photorhabdus laumondii中具有共同的调控模式。 |
Rili, L. |
PDF |
N/A |
Genes acquired by horizontal gene transfer share common regulatory patterns in Photorhabdus laumondii |
| 结合进化和蛋白质语言模型，利用D2Deep实现可解释的癌症驱动突变预测 |
Tzavella, K. |
PDF |
N/A |
Combining evolution and protein language models for an interpretable cancer driver mutation prediction with D2Deep |
| 体积电子显微镜揭示了人类内嗅皮层中独特的层状突触特性 |
Plaza-Alonso, S. |
PDF |
N/A |
Volume Electron Microscopy Reveals Unique Laminar Synaptic Characteristics in the Human Entorhinal Cortex |
| 新型神经启发式控制器通过内部模型在低级肢体任务中实现了模块化泛化 |
Munoz, D. |
PDF |
N/A |
New neural-inspired controller generalises modularity over lower limb tasks through internal models |
| behaviorMate：一种基于物联网的方法，用于适应性控制行为和基于导航的实验 |
Bowler, J. C. |
PDF |
N/A |
behaviorMate: An Intranet of Things Approach for Adaptable Control of Behavioral and Navigation-Based Experiments |
| 无偏倚地识别密集混合神经元培养物中的细胞身份 |
De Beuckeleer, S. |
PDF |
N/A |
Unbiased identification of cell identity in dense mixed neural cultures |
| 果蝇神经元类型的分裂GAL4驱动线资源 |
Meissner, G. W. |
PDF |
N/A |
A split-GAL4 driver line resource for Drosophila neuron types |
| 通过MALDI-TOF MS自动网络化录入艰难梭菌的核糖型 |
Sanchez-Blazquez, M. |
PDF |
N/A |
Automated web-based typing of Clostridioides difficile ribotypes via MALDI-TOF MS |
| GSK3抑制改善了纽芬兰ACM患者iPSC-心肌细胞的异常收缩能力 |
Noort, R. J. |
PDF |
N/A |
GSK3 inhibition ameliorates the abnormal contractility of Newfoundland ACM patient iPSC-cardiomyocytes |
| Omicron谱系BA.1、BA.2、BA.5.1、BQ.1、XBB.1.5、EG.5.1和JN.1.1的免疫逃逸和复制能力 |
Bekliz, M. |
PDF |
N/A |
Immune escape and replicative capacity of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1 |
| 探索自噬蛋白LC3B和GABARAP的芳基亚甲基-吲哚酮配体 |
Leveille, A. N. |
PDF |
N/A |
Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP |
| 观察气孔活动：在植物体内自主成像单个气孔运动 |
van den Berg, T. E. |
PDF |
N/A |
Viewing stomata in action: Autonomous in planta imaging of individual stomatal movement |
| 选择性激动GPR34可刺激小胶质细胞摄取和清除β淀粉样纤维 |
Etani, H. |
PDF |
N/A |
Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils |
| 撤回：噬菌体与抗生素在减少铜绿假单胞菌生物膜中的协同作用 |
Timilsina, S. |
PDF |
N/A |
WITHDRAWN: SYNERGISM OF BACTERIOPHAGE AND ANTIBIOTICS IN THE REDUCTION of Pseudomonas aeruginosa biofilm |
| 癌症中通过体细胞突变破坏肿瘤抑制基因的剪接和多聚腺苷酸化信号 |
Kainov, Y. |
PDF |
N/A |
Recurrent disruption of tumour suppressor genes in cancer by somatic mutations in cleavage and polyadenylation signals |
| 我的朋友MIROSLAV：一个可破解的开源硬件和软件平台，用于在家笼中进行高通量啮齿动物活动监测 |
Virag, D. |
PDF |
N/A |
My friend MIROSLAV: A Hackable Open-Source Hardware and Software Platform for High-Throughput Rodent Activity Monitoring in the Home Cage |
| 前额叶和感觉皮层中的预备性注意模板编码了与目标相关的信息 |
Zhou, Z. |
PDF |
N/A |
Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information |
| 从电子表格实验室数据模板到知识图谱：抗微生物药物耐药性研究领域中的FAIR数据之旅 |
Gadiya, Y. |
PDF |
N/A |
From spreadsheet lab data templates to knowledge graphs: A FAIR data journey in the domain of AMR research |
| 通过卡尔曼滤波提高了全身质心位置的准确性 |
Le Mouel, C. |
PDF |
N/A |
Improved accuracy of the whole body Center of Mass position through Kalman filtering |
| 12-脂氧合酶抑制延缓人基因替代小鼠自身免疫性糖尿病的发作 |
Nargis, T. |
PDF |
N/A |
12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice |
| 级联反向积分反馈以增强稳定性和性能 |
M. Zand, A. |
PDF |
N/A |
Cascaded Antithetic Integral Feedback for Enhanced Stability and Performance |
| 利用单组分融合蛋白在酿酒酵母中对磷酸盐应答基因进行光遗传学控制 |
Cleere, M. M. |
PDF |
N/A |
Optogenetic control of phosphate-responsive genes using single component fusion proteins in Saccharomyces cerevisiae |
| 评估基于排列的推断在神经影像数据偏最小二乘分析中的应用 |
Danyluik, M. |
PDF |
N/A |
Evaluating permutation-based inference for partial least squares analysis of neuroimaging data |
| 撤回：一种可溶性膳食纤维和矿物质配方对餐后血糖调节和饱腹感的初步研究。 |
haynes, m. m. |
PDF |
N/A |
WITHDRAWN: A preliminary investigation of a soluble dietary fibre and mineral formulation on post-prandial glucose regulation and satiation. |
| 湿地石楠林的生态系统动力学：环境驱动因素对植被的空间和时间效应 |
Damgaard, C. |
PDF |
N/A |
Ecosystem dynamics in wet heathlands: spatial and temporal effects of environmental drivers on the vegetation |
| 评估模型设定和先验敏感性对贝叶斯时间信号检验的影响 |
Tay, J. H. |
PDF |
N/A |
Assessing the effect of model specification and prior sensitivity on Bayesian tests of temporal signal |
| 配体介导的内吞作用在活体骨细胞中以一种性别二态性的方式受到调控 |
Matthews, M. D. |
PDF |
N/A |
Ligand-Mediated Endocytosis Is Regulated in a Sexually Dimorphic Way in Osteocytes in vivo |
| 神经反馈训练期间反馈处理和调节重新校准的神经机制 |
Pamplona, G. S. P. |
PDF |
N/A |
Neural Mechanisms of Feedback Processing and Regulation Recalibration during Neurofeedback Training |
| 竞争和频率依赖性共同决定了沙丘石楠生态系统的群落动态 |
Damgaard, C. |
PDF |
N/A |
Both competition and frequency-dependence determine community dynamics in a dune heath ecosystem |
| 一项关于不同土壤类型和地理区域抗生素抗性基因的宏基因组研究 |
Pillay, S. |
PDF |
N/A |
A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations |
| 甲基组揭示了两种植物物种种群中最近的进化变化 |
Korfmann, K. |
PDF |
N/A |
Methylomes reveal recent evolutionary changes in populations of two plant species |
| 大规模衰老：来自狗衰老项目的年轻狗和大型品种显示出加速的表观遗传衰老。 |
McCoy, B. M. |
PDF |
N/A |
Aging at scale: Younger dogs and larger breeds from the Dog Aging Project show accelerated epigenetic aging. |
| 小锚蛋白重复蛋白（Ankyrons）对SARS-CoV-2变种的功能活性及结合特异性研究。 |
Park, Y.-J. |
PDF |
N/A |
Functional Activity and Binding Specificity of small Ankyrin Repeat Proteins called Ankyrons against SARS-CoV-2 variants. |
| 小血管脑病遗传决定因子TRIM47通过NRF2抗氧化系统调控脑稳态 |
Duplaa, C. |
PDF |
N/A |
Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system |
| UniScore是一种通过多重搜索引擎对肽段鉴定进行统一和普遍评估的指标。 |
Tabata, T. |
PDF |
N/A |
UniScore, a unified and universal measure for peptide identification by multiple search engines |
| 微生物组知识图谱（MicrobiomeKG）：通过知识图谱连接微生物组研究与宿主健康 |
Goetz, S. L. |
PDF |
N/A |
MicrobiomeKG: Bridging Microbiome Research and Host Health Through Knowledge Graphs |
| 活性氧解毒作用有助于脓肿分枝杆菌的抗生素存活 |
Bates, N. A. |
PDF |
N/A |
Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival |
| 进化宏观生态学：在基于过程的、前向时间模拟模型中更明确地纳入系统发育信息 |
Culshaw, V. |
PDF |
N/A |
Evolutionary macroecology: Incorporating phylogenetic information more explicitly into process-based, forward time, simulation models |
| 真菌性脑膜炎病原体的表型景观揭示了其独特的生物学特性 |
Boucher, M. |
PDF |
N/A |
Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology |
| 结核菌噬菌体毒力比较研究 |
Rubino, I. |
PDF |
N/A |
Comparative study on the virulence of mycobacteriophages |
| 通过流形再现分析进行生成模型的验证 |
Lazzaro, N. |
PDF |
N/A |
Generative Models Validation via Manifold Recapitulation Analysis |
| Neuroligin 3 突显了果蝇社交距离中的性别二态性电路 |
Robinson, J. W. |
PDF |
N/A |
Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing |
| LYCEUM：学习在低覆盖率的古代基因组中识别拷贝数变异 |
Yilmaz, M. |
PDF |
N/A |
LYCEUM: Learning to call copy number variants on low coverage ancient genomes |
| LYCEUM：学习在低覆盖率的古代基因组中识别拷贝数变异 |
Yilmaz, M. A. |
PDF |
N/A |
LYCEUM: Learning to call copy number variants on low coverage ancient genomes |
| 伏隔核抑制性中间神经元表达的μ阿片受体促进亲和社交行为 |
Toddes, C. |
PDF |
N/A |
Mu opioid receptor expression by nucleus accumbens inhibitory interneurons promotes affiliative social behavior |
| 细胞基因组的表观遗传限制在进化上将遗传变异与功能联系起来。 |
Sinniah, E. |
PDF |
N/A |
Epigenetic constraint of cellular genomes evolutionarily links genetic variation to function |
| 普遍且反复的杂交现象防止了欧洲最受威胁的海鸟近亲繁殖的衰退 |
Izquierdo-Aranega, G. |
PDF |
N/A |
Pervasive and recurrent hybridisation prevents inbreeding depression in Europe's most threatened seabird |
| 活动依赖性的细胞外蛋白水解级联反应重塑细胞外基质以促进结构可塑性 |
Singh, J. B. |
PDF |
N/A |
Activity-dependent extracellular proteolytic cascade remodels ECM to promote structural plasticity |
| 广泛存在的适应性权衡现象：通过快速适应在大型实验种群中揭示的果蝇（Drosophila melanogaster） |
Bitter, M. C. |
PDF |
N/A |
Pervasive fitness trade-offs revealed by rapid adaption in large experimental populations of Drosophila melanogaster |
| 通过快速适应在大规模实验种群中揭示的普遍性适应性权衡——果蝇黑腹果蝇 |
Bitter, M. C. |
PDF |
N/A |
Pervasive fitness trade-offs revealed by rapid adaptation in large experimental populations of Drosophila melanogaster |
| 马拉维湖慈鲷中的大倒位与栖息地偏好、谱系和性别决定有关 |
Kumar, N. M. |
PDF |
N/A |
Large inversions in Lake Malawi cichlids are associated with habitat preference, lineage, and sex determination |
| 在实验性假单胞菌（Pseudomonas aeruginosa）的元种群中，快速适应和增强的遗传平行性 |
Chakraborty, P. |
PDF |
N/A |
Rapid adaptation and increased genetic parallelism in experimental metapopulations of Pseudomonas aeruginosa |
| 在秀丽隐杆线虫中Argonaute基因家族功能谱系的动态产生与消亡 |
Fusca, D. D. |
PDF |
N/A |
Dynamic birth and death of Argonaute gene family functional repertoire across Caenorhabditis nematodes |
| DeepRNA-Twist：基于语言模型引导的RNA扭转角预测与注意力-初始网络 |
Abir, A. R. |
PDF |
N/A |
DeepRNA-Twist: Language Model guided RNA Torsion Angle Prediction with Attention-Inception Network |
| 一种利用化学交联的蛋白质整合对接的新型离散几何方法 |
Zhang, Y. |
PDF |
N/A |
A new discrete-geometry approach for integrative docking of proteins using chemical crosslinks |
| 解析Musashi-1对RNA的识别，以设计用于体外和体内应用的蛋白质和RNA突变体 |
Perez-Rafols, A. |
PDF |
N/A |
Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications |
| SPONGE：简单先验组学网络生成器 |
Hovan, L. |
PDF |
N/A |
SPONGE: Simple Prior Omics Network GEnerator |
| 捕获单分子性质并不能确保生物分子相图的准确预测 |
Feito, A. |
PDF |
N/A |
Capturing single-molecule properties does not ensure accurate prediction of biomolecular phase diagrams |
| 来自NOD和NOR小鼠的血清及泪液自身抗体作为Sjögren's病局部和系统性炎症潜在的诊断指标 |
Kakan, S. S. |
PDF |
N/A |
Serum and Tear Autoantibodies from NOD and NOR Mice as Potential Diagnostic Indicators of Local and Systemic Inflammation in Sjögren's Disease |
| 通过单细胞RNA测序数据解析人肝第I组ILC的异质性和肿瘤相关动态 |
Zhang, Y. |
PDF |
N/A |
Dissecting the Heterogeneity and Tumor-Associated Dynamics of Human Liver Group I ILC via scRNA Sequencing Data |
| 中译：产婆蟾（Alytes）物种形成中的基因组、表型和环境相关性 |
Ambu, J. |
PDF |
N/A |
Genomic, phenotypic and environmental correlates of speciation in the midwife toads (Alytes) |
| 减数分裂驱动的代谢成本 |
Bradshaw, S. L. |
PDF |
N/A |
The metabolic costs of meiotic drive |
| 从大量组织表达数据推断基因调控的局限性 |
Chu, C. P. |
PDF |
N/A |
Limits to the inference of gene regulation from bulk tissue expression data |
| V-和VL-评分揭示蛋白质家族的病毒特征和起源 |
Zhou, K. |
PDF |
N/A |
V- and VL-Scores Uncover Viral Signatures and Origins of Protein Families |
| 脂质分层降低高曲率囊泡出芽的能垒 |
Schachter, I. |
PDF |
N/A |
Lipid Demixing Reduces Energy Barriers for High Curvature Vesicle Budding |
| 对帕金森病相关α-突触核蛋白的核内作用结构和功能的新认识 |
Jos, S. |
PDF |
N/A |
Structural and functional insights into nuclear role of Parkinson's Disease-associated α-Synuclein |
| IL-13/IL-13Rα2轴促进血管肉瘤细胞的增殖 |
Saito, H. |
PDF |
N/A |
IL-13/IL-13Rα2 axis promotes proliferation of angiosarcoma cells |
| CIGB-300逆转了MDR1转染的肺鳞状癌细胞的化疗耐药性。 |
Wang, M. |
PDF |
N/A |
CIGB-300 reverses chemo-resistance in MDR1-transfected lung squamous cancer cells |
| 铜绿假单胞菌代谢物3-酮基-C12HSL通过T2R14和线粒体钙单向转运体诱导细胞凋亡 |
Miller, Z. A. |
PDF |
N/A |
Pseudomonas aeruginosa metabolite 3-oxo-C12HSL induces apoptosis through T2R14 and the mitochondrial calcium uniporter |
| 降低肝脏线粒体能量代谢会损害胃预负荷和禁食后的食物摄入调控 |
Ponte, M. E. |
PDF |
N/A |
Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting |
| 降低肝脏线粒体能量代谢会损害胃预充填和禁食后的食物摄入调控 |
Ponte, M. E. |
PDF |
N/A |
Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting |
| 脂肪细胞素信号通过抑制平滑肌嘌呤能收缩性调节膀胱功能 |
Luo, Z. |
PDF |
N/A |
Adiponectin Signaling Regulates Urinary Bladder Function by Blunting Smooth Muscle Purinergic Contractility |
| 通过膜脂重塑调控外周脂肪储存能力的饮食控制 |
Tol, M. J. |
PDF |
N/A |
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling |
| 一种肿瘤分泌的蛋白质利用胰高血糖素释放导致宿主消瘦。 |
Ding, G. |
PDF |
N/A |
A tumor-secreted protein utilizes glucagon release to cause host wasting |
| 钙稳态反馈控制预测心房颤动的起始、重构和进展 |
Moise, N. |
PDF |
N/A |
Calcium homeostatic feedback control predicts atrial fibrillation initiation, remodeling, and progression |
| CpGPT：一种用于DNA甲基化的基础模型 |
de Lima Camillo, L. P. |
PDF |
N/A |
CpGPT: a Foundation Model for DNA Methylation |
| RGS10减轻慢性炎症应激引起的全身免疫失调 |
Jernigan, J. E. |
PDF |
N/A |
RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress |
| 工程细菌诱导的肿瘤特异性抗体促进膀胱癌免疫治疗 |
Rouanne, M. |
PDF |
N/A |
Tumor-specific antibodies elicited by engineered bacteria promote bladder cancer immunotherapy |
| 细胞因子诱导的人巨噬细胞在体外向与阿尔茨海默病相关的分子和细胞表型重编程 |
Podlesny-Drabiniok, A. |
PDF |
N/A |
Cytokine-induced reprogramming of human macrophages toward Alzheimer's disease-relevant molecular and cellular phenotypes in vitro |
| HP1/Swi6的磷酸化缓解了其与Suv39/Clr4在核小体上的竞争，并促进了H3K9三甲基化的扩散。 |
Kennedy, D. R. |
PDF |
N/A |
Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. |
| CCAFE：从GWAS汇总统计数据中估计病例和对照的等位基因频率 |
Stoneman, H. R. |
PDF |
N/A |
CCAFE: Estimating Case and Control Allele Frequencies from GWAS Summary Statistics |
| 高风险MYCN扩增和高风险MYCN非扩增神经母细胞瘤患者的比较网络分析 |
Chang, E. |
PDF |
N/A |
A comparative network analysis of high-risk MYCN amplified and high-risk MYCN non-amplified neuroblastoma patients |
| Hypermut 3：识别在特定核苷酸背景下允许多态性特征的具体突变模式 |
Lapp, Z. |
PDF |
N/A |
Hypermut 3: Identifying specific mutational patterns in a defined nucleotide context that allows multistate characters |
| 非洲刺鼠（Acomys）对致癌作用的抗性与肿瘤抑制基因的上调相关。 |
Vitorino, M. |
PDF |
N/A |
Resistance to Carcinogenesis in the African Spiny Mouse (Acomys) correlates with upregulation of tumor suppressor genes. |
| 乳铁蛋白衍生肽嵌合体诱导多发性骨髓瘤中依赖于半胱天冬酶的细胞死亡 |
Jang, Y.-S. |
PDF |
N/A |
Lactoferrin-Derived Peptide Chimera Induces Caspase-independent Cell Death in Multiple Myeloma |
| 慢性肾脏病中改变的全身生物能量储备使心脏更易出现更差的功能结果 |
Young, M. |
PDF |
N/A |
Altered systemic bioenergetic reserve in chronic kidney disease predisposes hearts to worse functional outcomes |
| 基于序列的TCR-肽表示：利用跨表位对比微调蛋白质语言模型 |
Im, C. |
PDF |
N/A |
Sequence-based TCR-Peptide Representations Using Cross-Epitope Contrastive Fine-tuning of Protein Language Models |
| 纳米尺度3D DNA追踪揭示了有丝分裂染色体自我组织的机制 |
Beckwith, K. S. |
PDF |
N/A |
Nanoscale 3D DNA tracing reveals the mechanism of self-organization of mitotic chromosomes |
| 肯尼亚西部小农玉米生产系统中农林复合种植的采用及其对土壤质量的影响 |
Nyuma, H. T. |
PDF |
N/A |
Agroforestry adoption and its influence on soil quality under smallholder maize production systems in western Kenya |
| 基于血液DNA甲基化的年龄预测 |
liu, R. |
PDF |
N/A |
Age Prediction based on Blood DNA Methylation |
| 使用酒石黄进行光学透明化可实现通过巩膜的深度光学相干断层扫描成像 |
Narawane, A. |
PDF |
N/A |
Optical Clearing with Tartrazine Enables Deep Transscleral Imaging with Optical Coherence Tomography |
| 可扩展制备坚韧且可回收的孢子承载型生物复合热塑性聚氨酯 |
Kim, H. S. |
PDF |
N/A |
Scalable Fabrication of a Tough and Recyclable Spore-Bearing Biocomposite Thermoplastic Polyurethane |
| PAV-spotter：利用信号互相关性识别目标捕获数据中的存在/缺失变异 |
de Visser, M. C. |
PDF |
N/A |
PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data |
| 功能性便携式血液透析机XKIDNEY的评估 |
Lee, J. K. |
PDF |
N/A |
Evaluation of a Functional Portable Hemodialysis Machine, XKIDNEY |
| 分箱与分类法的结合：TaxVAMB利用双模态变分自编码器提升宏基因组分箱效果 |
Kutuzova, S. |
PDF |
N/A |
Binning meets taxonomy: TaxVAMB improves metagenome binning using bi-modal variational autoencoder |
| 使用PHILHARMONIC解码非模式生物的功能性相互作用网络 |
Sledzieski, S. |
PDF |
N/A |
Decoding the Functional Interactome of Non-Model Organisms with PHILHARMONIC |
| 面向蛋白质生成模型鲁棒性评估：对度量标准的系统分析 |
Strashnov, P. |
PDF |
N/A |
Towards Robust Evaluation of Protein Generative Models: A Systematic Analysis of Metrics |
| 蛋白质和编码序列的整合使得语言模型能够相互增强 |
Zhao, H.-R. |
PDF |
N/A |
Integration of protein and coding sequences enables mutual augmentation of the language model |
| 用于分析力激活蛋白延伸和相互作用的DNA纳米装置 |
Zhou, K. |
PDF |
N/A |
DNA nanodevice for analysis of force-activated protein extension and interactions |
| 单分子分析揭示了变体PRC1复合物介导的染色质泛素化机制 |
Teslenko, A. |
PDF |
N/A |
Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes |
| 5hmC增强PARP捕获并恢复化学抗性BRCA1/2缺陷细胞对PARP抑制剂的敏感性 |
Kharat, S. S. |
PDF |
N/A |
5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells |
| 危地马拉宫颈癌进展分析——从癌前病变到侵袭性疾病 |
Robinson, E. |
PDF |
N/A |
Analysis of the progression of cervical cancer in Guatemala- from pre-malignancy to invasive disease |
| 苔藓植物Marchantia中组织平坦性的机械调控 |
Ferria, J. |
PDF |
N/A |
Mechanical regulation of tissue flatness in Marchantia |
| 拟南芥氨基酸转运蛋白UmamiT20赋予对灰霉病菌的易感性。 |
Prior, M. |
PDF |
N/A |
The Arabidopsis amino acid transporter UmamiT20 confers susceptibility to B. cinerea |
| AtTOC159受体通过β信号和位于C端的半乳糖脂特异性转运肽样序列，被靶向定位到叶绿体外膜。 |
Fish, M. |
PDF |
N/A |
AtTOC159 Receptors are Targeted to the Chloroplast Outer Membrane by a β-Signal and Galactolipid-Specific Transit Peptide-Like Sequence at the C-Terminus |
| 对光周期的敏感性是亚麻荠（Camelina sativa）中一种复杂的性状。 |
Ramirez-Corona, B. |
PDF |
N/A |
Sensitivity to photoperiod is a complex trait in Camelina sativa |
| 评估孟加拉国贾肖尔地区万寿菊（Tagetes erecta）栽培中田间病害的发生率和严重程度：研究结果 |
Shome, A. |
PDF |
N/A |
Assessing the Incidence and Severity of Field Diseases in Marigold (Tagetes erecta) Cultivation: Results from Jashore District, Bangladesh |
| 利用抗原和肽特征预测细菌中的免疫原性CD4+ T细胞表位 |
Marrama, D. |
PDF |
N/A |
Predicting Immunogenic CD4+ T Cell Epitopes in Bacteria Using Antigen and Peptide Features |
| 乳酸乳球菌乳亚种C60通过在肠道环境中对树突状细胞进行功能性修饰，促进B细胞产生免疫球蛋白A。 |
Saito, S. |
PDF |
N/A |
Lactococcus lactis subsp. cremoris C60 promotes immunoglobulin A production from B cells through functional modification of dendritic cells in intestinal environment |
| 通过工程化共刺激受体生成具有降低脱靶交叉反应性的T细胞 |
Cabezas Caballero, J. |
PDF |
N/A |
Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors |
| 由Arp2/3驱动的膜振荡在神经干细胞分裂期间收缩细胞间桥 |
LaFoya, B. |
PDF |
N/A |
Membrane oscillations driven by Arp2/3 constrict the intercellular bridge during neural stem cell divisions |
| 新型类肝细胞肝类器官再现了关键的成熟肝功能 |
Ardisasmita, A. I. |
PDF |
N/A |
Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions |
| 通过预测裂头绦虫（Schistocephalus solidus）的排泄/分泌蛋白和跨膜蛋白，揭示其种群间的蛋白质组分化 |
Wang, A. |
PDF |
N/A |
Among-Population Differentiation in the Tapeworm Proteome through Prediction of Excretory/Secretory and Transmembrane Proteins in Schistocephalus solidus |
| C9orf72扩展导致不稳定的叶酸敏感性脆性位点FRA9A的形成。 |
Mirceta, M. |
PDF |
N/A |
C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A |
| 一种由自噬基因ATG9B突变引起的新型神经发育罕见疾病的特征描述 |
Kilic, S. |
PDF |
N/A |
Characterization of a novel neurodevelopmental rare disease caused by a mutation within the autophagy gene ATG9B |
| 鉴定用于选择燕麦冠锈病抗性的诊断性KASP标记 |
Nguyen, D. T. |
PDF |
N/A |
Identification of diagnostic KASP markers for selection of crown rust resistance in oats |
| 潜在致病基因的概率性精细定位 |
Okamoto, J. |
PDF |
N/A |
Probabilistic Fine-mapping of Putative Causal Genes |
| VizCNV：一个集成平台，用于同时进行三联体基因组测序数据的相位BAF和CNV分析 |
Du, H. |
PDF |
N/A |
VizCNV: An integrated platform for concurrent phased BAF and CNV analysis with trio genome sequencing data |
| 传奇：在多模态转录组测序数据中识别共表达基因 |
Deng, T. |
PDF |
N/A |
LEGEND: Identifying Co-expressed Genes in Multimodal Transcriptomic Sequencing Data |
| 运动意识中的运动等效性 |
Fasola, J. |
PDF |
N/A |
Motor Equivalence in Motor Awareness |
| 基于物理的超快速大象鼻子建模 |
Kaczmarski, B. K. |
PDF |
N/A |
Ultra-fast physics-based modeling of the elephant trunk |
| 无标记光学活检揭示了糖尿病肾脏组织的生物分子和形态学特征，包括二维和三维 |
Fung, A. A. |
PDF |
N/A |
Label-Free Optical Biopsy Reveals Biomolecular and Morphological Features of Diabetic Kidney Tissue in 2D and 3D |
| 在循环中使用大型语言模型设计多样且高性能的蛋白质 |
Gomez-Uribe, C. |
PDF |
N/A |
Designing diverse and high-performance proteins with a large language model in the loop |
| 突破束缚：针对肝脏的无缝整合环状AAV载体的研发 |
Estes, B. J. G. |
PDF |
N/A |
Breaking Free: Development of Circular AAV Cargos for Targeted Seamless Integration in the Liver |
| 基于泛基因组的整数规划框架用于基因组推断 |
Chandra, G. |
PDF |
N/A |
Integer programming framework for pangenome-based genome inference |
| SpatialPPI 2.0：通过图注意力网络中的残基间分析增强蛋白质-蛋白质相互作用预测 |
Hu, W. |
PDF |
N/A |
SpatialPPI 2.0: Enhancing Protein-Protein Interaction Prediction through Inter-Residue Analysis in Graph Attention Networks |
| 解析人类蛋白质中内在无序性的复杂性 |
de Vries, I. |
PDF |
N/A |
Disentangling the CHAOS of intrinsic disorder in human proteins |
| 基准测试HelixFold3预测的Holo结构用于相对自由能扰动计算 |
Furui, K. |
PDF |
N/A |
Benchmarking HelixFold3-Predicted Holo Structures for Relative Free Energy Perturbation Calculations |
| 利用智能手机RGB影像和LiDAR点云进行增强型叶片氮素和地上生物量评估——以中国菠菜为例 |
Harikumar, A. |
PDF |
N/A |
Harnessing Smartphone RGB Imagery and LiDAR Point Cloud for Enhanced Leaf Nitrogen and Shoot Biomass Assessment - Chinese Spinach as a Case Study |
| 从组学数据中统一知识驱动的网络推断 |
Rodriguez-Mier, P. |
PDF |
N/A |
Unified knowledge-driven network inference from omics data |
| 利用细胞显像图像数据进行生物活性预测的半监督对比学习 |
Bushiri Pwesombo, D. |
PDF |
N/A |
Semi-supervised Contrastive Learning for Bioactivity Prediction using Cell Painting Image Data |
| 内源性大麻素亚型选择性的动态机制 |
Dutta, S. |
PDF |
N/A |
Dynamic Mechanism for Subtype Selectivity of Endocannabinoids |
| 解开应力纤维和未成束肌动蛋白网络对细胞形状响应的皮质张力各向异性贡献的纠缠 |
Fage, F. |
PDF |
N/A |
Disentangling the contributions of stress fibres and the unbundled actin meshwork to the anisotropy of cortical tension in response to cell shape |
| LSD1抑制减弱了BRAFV600E结直肠癌中靶向治疗诱导的谱系可塑性 |
Ladaika, C. |
PDF |
N/A |
LSD1 inhibition attenuates targeted therapy-induced lineage plasticity in BRAFV600E colorectal cancer |
| 内源性EWSR1-FLI1去泛素化位点等位基因能够调控肿瘤细胞系和异种移植模型中融合癌蛋白的表达 |
McGinnis, J. H. |
PDF |
N/A |
Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts |
| DNA甲基化随机性与转录变异性相关，并识别出在基因定义的AML亚型中普遍存在的表观遗传干扰。 |
Hilgart, E. |
PDF |
N/A |
DNA methylation stochasticity is linked to transcriptional variability and identifies convergent epigenetic disruption across genetically-defined subtypes of AML |
| 油菜素内酯和类黄酮醇能够提高花粉管萌发和生长的温度胁迫耐受性。 |
Matsuura-Tokita, K. |
PDF |
N/A |
Brassinosteroids and Flavonols Confer Temperature Stress Tolerance to Pollen Tube Germination and Growth |
| 通过体外重组大麦Mla NLR基因鉴定效应物结合的关键功能获得性残基 |
Zhang, X. |
PDF |
N/A |
Identification of a key gain-of-function residue for effector binding by in vitro shuffling of barley Mla NLR genes |
| 急性髓系白血病与慢性髓系白血病急变期中的共享遗传与调控机制 |
Basu, S. |
PDF |
N/A |
Shared Genetic and Regulatory Mechanisms in AcuteMyeloid Leukaemia and Blast Crisis Chronic MyeloidLeukaemia |
| 晚成雏大脑与婴儿发声学习的演化 |
Biazzi, R. B. |
PDF |
N/A |
Altricial brains and the evolution of infant vocal learning |
| 眶额皮层中的神经动力学揭示了认知策略 |
Schiereck, S. S. |
PDF |
N/A |
Neural dynamics in the orbitofrontal cortex reveal cognitive strategies |
| BT-11 在阿尔茨海默病中的再利用潜力及其作用机制的见解 |
Birnbaum, E. M. |
PDF |
N/A |
BT-11 repurposing potential for Alzheimer's disease and insights into its mode of actions |
| 神经退行性变会损害发育同步行为模式的巩固 |
Laufer, L. |
PDF |
N/A |
Neurodegeneration impairs the consolidation of developmentally synchronized behavioral patterns |
| 先验的相关性如何？贝叶斯因果推断在易变环境中的动态感知 |
Meijer, D. |
PDF |
N/A |
How relevant is the prior? Bayesian causal inference for dynamic perception in volatile environments |
| 动脉内脱氧核糖核酸酶治疗可改善老年小鼠的卒中预后 |
Yin, J. |
PDF |
N/A |
Intra-arterial Deoxyribonuclease therapy improves stroke outcomes in aged mice |
| Ephrin介导的树突-树突排斥作用调节中枢神经系统中树突的区室特异性靶向定位 |
Deng, X. |
PDF |
N/A |
Ephrin-mediated dendrite-dendrite repulsion regulates compartment- specific targeting of dendrites in the central nervous system |
| 用于可植入神经设备的软生物相容性聚合物光纤锥 |
Meneghetti, M. |
PDF |
N/A |
Soft biocompatible polymer optical fiber tapers for implantable neural devices |
| 分泌型磷脂酶PLA2G12A通过脂解修饰胞外囊泡促进溶血磷脂信号传导，从而促进致病性Th17分化。 |
Mochizuki, C. |
PDF |
N/A |
Secreted phospholipase PLA2G12A-driven lysophospholipid signaling via lipolytic modification of extracellular vesicles facilitates pathogenic Th17 differentiation |
| Sirtuin2阻断抑制了巨噬细胞和人源化小鼠中人类免疫缺陷病毒-1和结核分枝杆菌的复制 |
Singh, V. K. |
PDF |
N/A |
Sirtuin2 blockade inhibits replication of Human Immunodeficiency Virus-1 and 1 Mycobacterium tuberculosis in macrophages and humanized mice |
| WAVE1和WAVE2在细胞进入过程中促进人乳头瘤病毒驱动的肌动蛋白聚合。 |
Fernandez, D. J. |
PDF |
N/A |
WAVE1 and WAVE2 facilitate human papillomavirus-driven actin polymerization during cellular entry |
| Notch、β-连环蛋白和MAPK信号通路在双胚层动物Nematostella vectensis中分离了内胚层和中胚层。 |
Haillot, E. |
PDF |
N/A |
Notch, beta-catenin and MAPK signaling segregate endoderm and mesoderm in the diploblast Nematostella vectensis |
| 海葵生命史中基质组分的分子动力学 |
Bergheim, B. G. |
PDF |
N/A |
Molecular dynamics of the matrisome across sea anemone life history |
| 线粒体氧化还原开关授权动物形态发生的开始 |
Kahlin, U. |
PDF |
N/A |
A mitochondrial redox switch licenses the onset of morphogenesis in animals |
| eIF4ET 调控减数分裂蛋白质组水平，以促进卵母细胞的形成和储存 |
Bhatia, P. |
PDF |
N/A |
eIF4ET regulates meiotic proteome levels to enable oocyte formation and storage |
| 西澳大利亚城市灌木丛火灾后的兰花输家和赢家：与其他特征深度整合的响应连续体 |
Brundrett, M. C. |
PDF |
N/A |
Orchid losers and winners after fire in West Australian urban bushland: A response continuum deeply integrated with other traits |
| 南极生物安全政策有效地管理了外来物种引入的比率。 |
Leihy, R. I. |
PDF |
N/A |
Antarctic biosecurity policy effectively manages the rates of alien introductions |
| 跨物种分析揭示无普遍的程序性衰老机制：斑马鱼、果蝇和线虫单细胞转录组学的见解 |
Niu, Y. |
PDF |
N/A |
Cross-Species Analysis Reveals No Universal Programmed Aging Mechanism: Insights from Single-Cell Transcriptomics in Zebrafish, Fruit Fly, and Nematode |
| 结合核基因组和线粒体基因组系统发育的生物信息学研究，以定义鞘翅目分类的关键节点 |
Creedy, T. J. |
PDF |
N/A |
Bioinformatics of combined nuclear and mitochondrial phylogenomics to define key nodes for the classification of Coleoptera |
| 深入研究基因组以精确定位XX虹鳟自发性逆转的QTL位置 |
Dehaullon, A. |
PDF |
N/A |
In-depth investigation of genome to refine QTL positions for spontaneous sex-reversal in XX rainbow trout |
| 染色体性别和性腺性别对小鼠社会动机的影响不同 |
Chaturvedi, S. M. |
PDF |
N/A |
Chromosomal and gonadal sex have differing effects on social motivation in mice |
| Cloudgene 3：将Nextflow管道转化为强大的Web服务 |
Forer, L. |
PDF |
N/A |
Cloudgene 3: Transforming Nextflow Pipelines into Powerful Web Services |
| scMultiNODE：多模态时间单细胞数据的整合模型 |
Zhang, J. |
PDF |
N/A |
scMultiNODE: Integrative Model for Multi-Modal Temporal Single-Cell Data |
| GenePert：利用GenePT嵌入进行基因扰动预测 |
Chen, Y. T. |
PDF |
N/A |
GenePert: Leveraging GenePT Embeddings for Gene Perturbation Prediction |
| 通过异质性测序识别细胞反应的调节因子 |
Berg, K. |
PDF |
N/A |
Identifying Modulators of Cellular Responses by Heterogeneity-sequencing |
| 基于反应类型评分的化学酶合成规划 |
Li, H. |
PDF |
N/A |
Chemoenzymatic Synthesis Planning Guided by Reaction Type Score |
| 新孢子虫（Neospora caninum）对宿主细胞膜生物物理动力学的调控：基于超光谱成像和相量分析的LAURDAN荧光研究 |
Diaz, M. |
PDF |
N/A |
Modulation of Host Cell Membrane Biophysics Dynamics by Neospora caninum: A Study Using LAURDAN Fluorescence with Hyperspectral Imaging and Phasor Analysis |
| LassoESM：一种专为增强套索肽性质预测而定制的语言模型 |
Mi, X. |
PDF |
N/A |
LassoESM: A tailored language model for enhanced lasso peptide property prediction |
| 从单分子荧光测量中获得的特定位置自由能表面参数，这些测量针对的是位于DNA复制叉接合处的激子耦合（iCy3）2二聚体探针 |
Maurer, J. |
PDF |
N/A |
Site-specific free energy surface parameters from single-molecule fluorescence measurements of exciton-coupled (iCy3)2 dimer probes positioned at DNA replication fork junctions |
| 成纤维细胞激活蛋白定义了局部ccRCC中与上皮-间质转化相关的侵袭性癌细胞状态和预后 |
Pellinen, T. |
PDF |
N/A |
Fibroblast activation protein defines aggressive EMT-associated cancer cell state and prognosis in localized ccRCC |
| 尤文氏肉瘤的起源：神经嵴向中胚层的胚胎重编程 |
Vasileva, E. |
PDF |
N/A |
Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm |
| 多亚基自噬捕获复合物促进胰腺癌中ER停滞的MHC-I降解。 |
Berquez, M. |
PDF |
N/A |
A multi-subunit autophagic capture complex facilitates degradation of ER stalled MHC-I in pancreatic cancer. |
| 肥胖通过激活PPARD/PDK4/ANGPTL4通路诱导胃平滑肌细胞的表型转换。 |
Dekkar, S. |
PDF |
N/A |
Obesity induces phenotypic switching of gastric smooth muscle cells through the activation of the PPARD/PDK4/ANGPTL4 pathway |
| 质体编码的RNA聚合酶构建了一个光诱导光合作用的物流链。 |
Gillet, F.-X. |
PDF |
N/A |
The plastid-encoded RNA polymerase structures a logistic chain for light-induced photosynthesis |
| 对多种普通小麦种质资源中的籽粒进行多性状评价，包括高蛋白品种 |
KOSINA, R. |
PDF |
N/A |
Multi-character assessment of caryopsis in diverse common wheat germplasm,including high protein breeds |
| 光通过解除psbA顺式ORF对翻译因子HCF173的抑制作用，激活植物中psbA的翻译。 |
Williams-Carrier, R. |
PDF |
N/A |
Light activates psbA translation in plants by relieving inhibition of translation factor HCF173 by the psbA ORF in cis |
| 铝通过ABA诱导大麦根部的木栓质生物合成 |
Meng, H. |
PDF |
N/A |
Aluminium induces suberin biosynthesis in barley roots via ABA |
| 不同年龄阶段大脑网络灵活性在运动学习中的不同作用 |
Uehara, K. |
PDF |
N/A |
Distinct roles of brain network flexibility in motor learning across age |
| 躯体运动分离将睡眠时长与社会经济背景、屏幕使用时间、认知功能和精神病理学联系起来。 |
Michael, C. |
PDF |
N/A |
Somatomotor disconnection links sleep duration with socioeconomic context, screen time, cognition, and psychopathology |
| 交易地点以换取空间：提高位置分辨率会降低海马编码中的情境容量 |
Rooke, S. |
PDF |
N/A |
Trading Place for Space: Increasing Location Resolution Reduces Contextual Capacity in Hippocampal Codes |
| 一种怀旧脑音乐接口，用于增强年轻人和老年人群体的怀旧情感、幸福感及记忆鲜活度 |
Sakakibara, Y. |
PDF |
N/A |
A Nostalgia Brain-Music Interface for Enhancing Nostalgia, Well-Being, and Memory Vividness in Young and Elderly Individuals |
| 发作相关啁啾声作为监测癫痫进展的生物标志物 |
Bahador, N. |
PDF |
N/A |
Ictal-Related Chirp as a Biomarker for Monitoring Seizure Progression |
| 工作记忆中的任务无关特征会改变当前的视觉处理 |
Shi, H. |
PDF |
N/A |
Task-irrelevant features in working memory alter current visual processing |
| 视觉引导运动过程中细胞类型特异性纹状体集合活动的动态失衡。 |
Howe, M. |
PDF |
N/A |
Dynamic imbalances in cell-type specific striatal ensemble activity during visually guided locomotion. |
| 随着年龄的增长，沉思、担忧和积极思考等情绪大脑状态的独特性也会增加。 |
Misaki, M. |
PDF |
N/A |
Aging increases the distinctiveness of emotional brain states across rumination, worry, and positive thinking |
| 哺乳期大鼠的幼崽防御行为：伏隔核壳区神经肽信号传导及其相互作用的机制 |
Sanson, A. |
PDF |
N/A |
Pup defence in lactating rats: The underlying neuropeptide signalling and their interactions in the nucleus accumbens shell |
| 基准测试用于推断TCR特异性的无监督方法 |
Jouannet, C. |
PDF |
N/A |
Benchmarking unsupervised methods for inferring TCR specificity |
| DDO佐剂流感病毒A型核蛋白mRNA疫苗诱导出强大的体液和细胞型1免疫反应，并保护小鼠免受挑战。 |
Gnazzo, V. |
PDF |
N/A |
DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge |
| 新生儿重症监护室中母乳、捐赠母乳和母乳强化剂中的EGF和IgA |
Tamar, C. |
PDF |
N/A |
EGF and IgA in maternal milk, donor milk and milk fortifiers in the Neonatal Intensive Care Unit setting |
| 含MT1-MMP的连接外泌体在乳腺癌进展中促进细胞外基质降解 |
Palmulli, R. |
PDF |
N/A |
Tethered exosomes containing MT1-MMP contribute to extracellular matrix degradation during breast cancer progression |
| 在基因图增强的细胞状态流形上引导细胞转变 |
Wang, T. |
PDF |
N/A |
Directing cellular transitions on gene graph-enhanced cell state manifold |
| 奥斯卡雷拉海绵属：隐藏的彩色多样性 |
Guiollot, E. |
PDF |
N/A |
The Oscarella sponges genus: a hidden yet colorful diversity |
| 多变量性状演化：基于系统发育的定量遗传G矩阵演化模型。 |
Blomberg, S. P. |
PDF |
N/A |
Multivariate Trait Evolution: Models for the Evolution of the Quantitative Genetic G-Matrix on Phylogenies. |
| 基因组洞察指导肺癌和膀胱肿瘤一线免疫治疗个性化反应 |
Brea-Iglesias, J. |
PDF |
N/A |
Genomic Insights Guiding Personalized First-Line Immunotherapy Response in Lung and Bladder Tumors |
| 探索细鳞甲螨（Oppia nitens）的基因组：环境应激响应与毒性适应 |
Adedokun, A. A. |
PDF |
N/A |
Exploring The Genome of The Oribatid Mite, Oppia Nitens: Environmental Stress Response and Toxicity Adaptation |
| 重温亚里士多德对蜜蜂的观察：蜜蜂普遍表现出高度的花期恒定性，但这种特性是由当地丰富的开花植物种类所塑造的。 |
Shrotri, S. |
PDF |
N/A |
Revisiting Aristotle's observation on bees: High floral constancy is common among bees but it is shaped by the locally abundant flowering species |
| 动态肾脏类器官微生理分析平台 |
Hong, S. |
PDF |
N/A |
Dynamic Kidney Organoid Microphysiological Analysis Platform |
| 利用大型语言模型实现异质生物医学样本元数据的自动化协调与大规模整合 |
Higashi, K. |
PDF |
N/A |
Automated Harmonization and Large-Scale Integration of Heterogeneous Biomedical Sample Metadata Using Large Language Models |
| 通过融合基于spot的空间转录组学、位置和组织学信息，利用图卷积网络推断单细胞分辨率的空间基因表达 |
Xue, S. |
PDF |
N/A |
Inferring single-cell resolution spatial gene expression via fusing spot-based spatial transcriptomics, location and histology using GCN |
| 利用系统发育和祖先序列重建方法，探索在猪与人之间传播的甲型流感病毒的遗传特征 |
Anker, K. M. |
PDF |
N/A |
Exploring genetic signatures of zoonotic influenza A virus at the swine-human interface with phylogenetic and ancestral sequence reconstruction |
| 胰腺腺泡-导管化生过渡状态的DNA甲基化记忆在没有Kras突变的情况下改变Kras下游PI3K和Rho GTPase信号传导 |
Feinberg, A. P. |
PDF |
N/A |
DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation |
| 细胞内双调蛋白对于BRCA2突变/+乳腺上皮细胞在应对复制应激时维持异染色质稳定和基因组稳定性至关重要。 |
Jiang, T. |
PDF |
N/A |
Intracellular amphiregulin is critical for heterochromatin maintenance and genomic stability in response to replication stress in BRCA2mut/+mammary epithelial cells |
| 几丁质酶-1抑制逆转了代谢失调，并在非酒精性脂肪性肝炎（MASH）动物模型中恢复了体内平衡。 |
Drzewicka, K. |
PDF |
N/A |
Chitinase-1 inhibition reverses metabolic dysregulation and restores homeostasis in MASH animal models |
| 冰与气：年轻北美鹅掌楸叶片中冻融栓塞与冰冻扩散的可视化 |
Johnson, K. M. |
PDF |
N/A |
Ice and air: Visualisation of freeze-thaw embolism and freezing spread in young L. tulipifera leaves |
| 差异基因表达分析鉴定出一组来自Solanum chacoense胚珠的防御素样肽，具有体外花粉管吸引活性。 |
Liu, Y. |
PDF |
N/A |
Differential gene expression analysis identifies a group of defensin like peptides from Solanum chacoense ovules with in vitro pollen tube attraction activity |
| 选择性育种以确定性和光周期敏感性为目标的普通豆（Phaseolus vulgaris L.） |
Denning-James, K. |
PDF |
N/A |
Selective breeding for determinacy and photoperiod sensitivity in common bean (Phaseolus vulgaris L.) |
| E2F4DN对p38MAPK磷酸化的抵抗通过Cited2减轻了DNA损伤诱导的神经元死亡 |
Llabres-Mas, A. M. |
PDF |
N/A |
Resistance of E2F4DN to p38MAPK phosphorylation attenuates DNA damage-induced neuronal death via Cited2 |
| 双光子成像中血流动力学阻塞效应的定量分析 |
Yogesh, B. |
PDF |
N/A |
Quantification of the effect of hemodynamic occlusion in two-photon imaging |
| 一种基于功能性磁共振成像（fMRI）的方法，用于测量视觉皮层中视觉场各部分的对比度敏感度 |
Chow-Wing-Bom, H. T. |
PDF |
N/A |
An fMRI-based Approach for Measuring Contrast Sensitivity Across the Visual Field in Visual Cortex |
| 使用多线性探针在小鼠中进行经颅脑全域功能超声和超声定位显微镜 |
Vert, M. |
PDF |
N/A |
Transcranial Brain-Wide Functional Ultrasound and Ultrasound Localization Microscopy in Mice using Multilinear Probes |
| Slit调控果蝇大脑中树突和轴突的区室特异性靶向 |
Deng, X. |
PDF |
N/A |
Slit regulates compartment-specific targeting of dendrites and axons in the Drosophila brain |
| 记忆系统的适应不良损害了背侧CA1依赖的时间绑定和陈述性记忆——以自闭症Cntnap2敲除小鼠模型为例 |
Rawlinson, E. C. |
PDF |
N/A |
Maladaptation of Memory Systems Impairs Dorsal CA1-Dependent Temporal Binding and Declarative Memory in The Cntnap2 Knockout Mouse Model of Autism |
| 揭示头颈部癌症患者对SARS-CoV-2的体液和细胞免疫反应：罗马尼亚疫苗接种与自然感染的比较研究 |
Marutescu, L. |
PDF |
N/A |
Unveiling Humoral and Cellular Immune Responses to SARS-CoV-2 in Head and Neck Cancer: A Comparative Study of Vaccination and Natural Infection in Romania |
| 假单胞菌利用混合碳源生产异戊二烯醇的替代途径导致乙酸耐受性的变化 |
de Siqueira, G. M. V. |
PDF |
N/A |
Alternate routes to acetate tolerance lead to varied isoprenol production from mixed carbon sources in Pseudomonas putida |
| 克服艰难梭菌分型中的重复性和变异性挑战 |
Bravo-Anton, L. |
PDF |
N/A |
Overcoming Challenges of Reproducibility and Variability for the Clostridioides difficile typification |
| 针对肿瘤相关微生物具核梭杆菌（F. nucleatum）的靶向治疗：利用生物工程益生菌表达引导性抗菌肽（gAMP） |
Choudhury, A. |
PDF |
N/A |
Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP) |
| NINJ1是HSV-1在小鼠巨噬细胞中的限制因子 |
Broz, P. |
PDF |
N/A |
NINJ1 is a restriction factor for HSV-1 in mouse macrophages |
| 温带噬菌体提高抗生素在秀丽隐杆线虫感染模型中的有效性 |
Fatima, R. |
PDF |
N/A |
Temperate phages increase antibiotic effectiveness in a Caenorhabditis elegans infection model |
| 肝素在宿主抵抗播散性念珠菌病中的关键作用 |
Arekar, T. |
PDF |
N/A |
Essential role of Hepcidin in host resistance to disseminated candidiasis |
| Tad菌毛排列复合体的结构揭示了菌毛延伸的周质通道 |
Evans, S. L. |
PDF |
N/A |
The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension |
| 替米沙坦主要通过AT1/PPARγ轴抑制JEV感染。 |
Datey, A. |
PDF |
N/A |
Telmisartan impedes JEV infection predominately via AT1/PPARγ axis |
| 对反义抗生素耐药决定因素的系统鉴定表明，适应策略依赖于递送肽 |
Mulkern, A. J. |
PDF |
N/A |
A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide |
| 鉴定出一组基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂，能够抑制冠状病毒的复制 |
Pfannenstiel, J. J. |
PDF |
N/A |
Identification of a series of pyrrolo-pyrimidine based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication |
| 机械化学图案化定位了管腔上皮组织者的位置 |
Weevers, S. L. |
PDF |
N/A |
Mechanochemical Patterning Localizes the Organizer of a Luminal Epithelium |
| 描述外来物种对西南不列颠哥伦比亚地区单体三刺鱼（Gasterosteus aculeatus）种群形态的影响 |
Kienzle, H. M. |
PDF |
N/A |
Characterizing the impacts of exotic species on the morphology of solitary threespine stickleback (Gasterosteus aculeatus) populations in southwestern British Columbia |
| 利用真核细胞重编程的tracrRNAs在人类细胞中劫持并记录细胞内RNAs |
Lee, S.-H. |
PDF |
N/A |
Hijacking and recording intracellular RNAs in human cells using eukaryotic reprogrammed tracrRNAs |
| 多铜氧化酶漆酶的定向进化用于细胞表面邻近标记和电子显微镜技术 |
Lee, S.-Y. |
PDF |
N/A |
Directed evolution of the multicopper oxidase laccase for cell surface proximity labeling and electron microscopy |
| 基于模式的基因组挖掘指导从海洋链霉菌中发现抗菌药物吲哚吡咯A。 |
Sweeney, D. |
PDF |
N/A |
Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomycete. |
| 碳纳米点作为红色荧光探针用于紫杉醇治疗期间DNA动力学的超分辨率显微成像 |
Garg, R. |
PDF |
N/A |
Carbon nanodots as a red emissive fluorescent probe for the super-resolution microscopy of DNA dynamics during paclitaxel treatment |
| 结核分枝杆菌mce1操纵子中长链脂肪酸辅酶A合成酶FadD5的结构酶学研究 |
Rahman, M. A. |
PDF |
N/A |
Structural enzymological studies of the long chain fatty acyl-CoA synthetase FadD5 from the mce1 operon of Mycobacterium tuberculosis |
| VAPOR：使用传输算子的变分自编码器解耦发育中的共发生生物过程 |
Sheng, J. |
PDF |
N/A |
VAPOR: Variational autoencoder with transport operators decouples co-occurring biological processes in development |
| DNMT3AR882H在原发性人类急性髓系白血病中并非疾病维持所必需，但与白血病干细胞频率增加相关 |
Koehnke, T. |
PDF |
N/A |
DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency |
| 核糖体生物发生超激活与ErbB信号传导介导的网络重塑导致对FGFR2抑制的适应性抗性 |
Zhang, T. |
PDF |
N/A |
Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition |
| 主基因型塑造了硬粒小麦的根系真菌群落 |
TRINQUIER, M. |
PDF |
N/A |
Host genotype shapes root mycobiota in durum wheat |
| 基于表面的深度学习皮质形状分析方法 |
Im, Y. |
PDF |
N/A |
A Surface-based deep learning approach for cortical shape analysis |
| 在并行操作和监控环境时，自适应的目光与手部协调 |
Fooken, J. |
PDF |
N/A |
Adaptive Gaze and Hand Coordination while Manipulating and Monitoring the Environment in Parallel |
| 兴奋性毒性诱导的神经营养素受体TrkB-FL的逆向运输调节高尔基体稳定性，并成为中风神经保护的靶点 |
Esteban-Ortega, G. M. |
PDF |
N/A |
Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection |
| Ninjurin-1介导的质膜破裂是一个两步过程，需要细胞膨胀。 |
Hartenian, E. |
PDF |
N/A |
Ninjurin-1 mediated plasma membrane rupture is a two-step process requiring cell swelling |
| 白色念珠菌多药耐药ABC转运蛋白CDR1的结构、动力学和进化 |
Shin, J. |
PDF |
N/A |
Structure, dynamics and evolution of the Candida albicans multi-drug resistance ABC transporter CDR1 |
| 植物化学特性及印楝素对选定人类细菌病原体的抗菌特性 |
Ibuot, A. A. |
PDF |
N/A |
Phytochemical characterization and antimicrobial properties of Azadirachtin indica against selected bacterial human pathogens |
| 年龄、性别和线粒体单倍型影响遗传多样性大鼠模型中的肠道微生物组组成和代谢物。 |
Nguyen, H. V. M. |
PDF |
N/A |
Age, Sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model. |
| 抗生素的杀伤力决定了分枝杆菌感染的结果 |
Jovanovic, A. |
PDF |
N/A |
Antibiotic lethality dictates mycobacterial infection outcomes |
| 鉴定出一大批具有广泛宿主范围的Enterobacter巨型噬菌体，这些噬菌体可感染致病性γ-变形菌 |
Kanhirun, N. |
PDF |
N/A |
Identification of a large cohort of Enterobacter jumbo phages with broad host ranges across pathogenic Gammaproteobacteria |
| 德克萨斯州分离的牛源性流感A(H5N1)病毒的复制动力学、致病性及病毒诱导的细胞反应 |
Mostafa, A. |
PDF |
N/A |
Replication Kinetics, Pathogenicity and Virus-induced Cellular Responses of Cattle-origin Influenza A(H5N1) Isolates from Texas, United States |
| 工程化多价抗体片段的结构景观及其作为结晶支架的应用 |
Kedari, A. |
PDF |
N/A |
Structural landscape of engineered multivalent antibody fragments and their application as crystallization scaffolds |
| 靶向二斑叶螨Tetranychus urticae前体rRNA的反义DNA杀螨剂作为增强真菌绿僵菌Metarhizium robertsii功效的试剂 |
Gavrilova, D. |
PDF |
N/A |
Antisense DNA acaricide targeting pre-rRNA of two-spotted spider mite Tetranychus urticae as efficacy-enhancing agent of fungus Metarhizium robertsii |
| 植物线粒体核糖体成熟与翻译的结构研究 |
Skaltsogiannis, V. |
PDF |
N/A |
Structural insights into maturation and translationof a plant mitoribosome |
| TreeFormer：一种基于Transformer的树重排操作，用于系统发育重建 |
Ly-Trong, N. |
PDF |
N/A |
TreeFormer: A transformer-based tree rearrangement operation for phylogenetic reconstruction |
| TaxonGPT：利用生成式人工智能进行分类学分类 |
Huang, H. |
PDF |
N/A |
TaxonGPT: Taxonomic Classification Using Generative Artificial Intelligence |
| 利用斯坦波霉素聚酮合酶中酰基转移酶的固有杂泛性进行类似物的突变合成 |
Su, L. |
PDF |
N/A |
Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues |
| SCAD递送平台：一种高效的中枢神经系统和肝外寡核苷酸治疗的新方法 |
Kang, M. |
PDF |
N/A |
SCAD Delivery Platform: A Novel Approach for Efficient CNS and Extrahepatic Oligonucleotide Therapeutics |
| 突变株和非突变株枯草芽孢杆菌对利用西瓜籽生产奥吉里（ogiri）的微生物多样性及理化性质的影响 |
Babatuyi, C. |
PDF |
N/A |
Effects of mutant and non-mutant strains of Bacillus subtilis to produce ogiri from Citrullus vulgaris seeds on their microbial diversity and physicochemical properties |
| 一种紧密调控酵母RNA稳态的共转录机制 |
Esteban-Serna, S. |
PDF |
N/A |
A co-transcriptional mechanism for tightly controlling RNA homeostasis in yeast |
| 从数千个随机内含子中学习的内含子介导增强的序列决定因素 |
Kowal, E. J. |
PDF |
N/A |
Sequence determinants of intron-mediated enhancement learned from thousands of random introns |
| 研究泼尼松龙对杜氏肌营养不良小鼠模型行为的影响 |
Verhaeg, M. |
PDF |
N/A |
Investigating the effects of prednisolone on behavior in mouse models of Duchenne muscular dystrophy |
| 共享转录组特征揭示了突触修剪作为阿尔茨海默病与癫痫之间的联系 |
Li, H. |
PDF |
N/A |
Shared Transcriptomic Signatures Reveal Synaptic Pruning as a Link Between Alzheimer's Disease and Epilepsy |
| 皮质-伏隔核通路的转录组分析揭示了应激易感性背后的性别特异性改变 |
Pessoni, A. M. |
PDF |
N/A |
Transcriptional profiling of the cortico-accumbal pathway reveals sex-specific alterations underlying stress susceptibility |
| 通过表达谱分析和结构分析揭示重复基因的功能命运 |
Warwick Vesztrocy, A. |
PDF |
N/A |
Unveiling the Functional Fate of Duplicated Genes Through Expression Profiling and Structural Analysis |
| 通过适当建模遗传、环境和社会文化因素，提高在代表性不足群体中的全基因组关联研究（GWAS）表现 |
Cataldo-Ramirez, C. |
PDF |
N/A |
Improving GWAS performance in underrepresented groups by appropriate modeling of genetics, environment, and sociocultural factors |
| 学习推断传递性：前运动皮层中对心理直线上序列排序的推断 |
Raglio, S. |
PDF |
N/A |
Learning to infer transitively: serial ordering on a mental line in premotor cortex |