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BioRxiv 2024-11-02 Papers

标题 作者 PDF链接 代码仓库 Title
阳光强度对水稻(Oryza sativa ssp. indica)地方品种开花时间和暴露持续时间的影响 Deb, D. PDF N/A The Effect of Sunlight Intensity on Flower Opening Time and Exposure Duration in Rice (Oryza sativa ssp. indica) Landraces
一个整合了机制的模型,描述了在单一资源上进行的开发性和干扰性竞争,产生了广泛的共存现象。 Smith, D. J. B. PDF N/A A Mechanistically Integrated Model of Exploitative and Interference Competition over a Single Resource Produces Widespread Coexistence
精神分裂症相关DRD2基因突变的影响及其与断奶后孤立小鼠模型中社会行为与生化变化的关联 Mukesh, N. PDF N/A Effect of Schizophrenia linked DRD2 gene mutations and correlation of social behavior with biochemical changes in a post-weaning isolated mouse model
敲除细胞周期依赖性激酶8和19会导致细胞周期蛋白C的耗竭,并抑制小鼠的精子发生和雄性生育能力。 Bruter, A. V. PDF N/A Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice
不同物种和发育阶段的海马和新皮层中阿片类药物介导的抑制性抑制的差异 Caccavano, A. P. PDF N/A Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development
通过双功能HSV载体治疗性疫苗清除慢性SIV感染猕猴体内的病毒潜伏期 Wen, Z. PDF N/A Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
使用生成模型预测蛋白质折叠的绝对稳定性 Cagiada, M. PDF N/A Predicting absolute protein folding stability using generative models
互补的遗传和表观遗传变化有助于快速适应多种全球变化压力 Brennan, R. PDF N/A Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors
放射科医生感知错误的神经认知机制:初步研究结果 Bruno, M. A. PDF N/A Neurocognitive Mechanism of Radiologists Perceptual Errors: Results of Preliminary Studies
Dnajc12敲除小鼠的特征分析,作为低多巴胺能的模型 Deng, I. B. PDF N/A Characterization of Dnajc12 knockout mice, a model of hypodopaminergia
一种经济实惠的解决方案,用于研究斑胸草雀颅内脑电图(iEEG)信号 Abolghasemi, M.-M. PDF N/A An affordable solution for investigating zebra finch intracranial electroencephalography (iEEG) signals
利用DNA折纸纳米块对果蝇E-钙粘蛋白外域片段及其相互作用的纳米尺度可视化研究 Oda, H. PDF N/A Nanoscale visualization of Drosophila E-cadherin ectodomain fragments and their interactions using DNA origami nanoblocks
身体自主感神经相关性 Regev Krugwasser, A. PDF N/A Neural Correlates of the Embodied Sense of Agency
m6A RNA修饰在转录后水平上调控突触功能,这一过程在衰老以及突触核蛋白病的小鼠模型中发挥作用。 Chopra, A. PDF N/A The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy
视神经头处的轴突运输受损在新型Cre诱导的小鼠青光眼模型中促进了神经退行性变 Kaipa, B. R. PDF N/A Impaired axonal transport at the optic nerve head contributes to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucoma
p24家族成员TMED9通过快速内质网应激诱导的出口途径,协调错误折叠的GPI锚定蛋白从内质网到高尔基体的清除。 Ronzier, E. PDF N/A The p24-family member, TMED9, coordinates clearance of misfolded GPI-anchored proteins from the ER to the Golgi via the Rapid ER Stress-Induced Export pathway
视觉特征注意力控制的分层组织 Meyyappan, S. PDF N/A Hierarchical Organization of Visual Feature Attention Control
阻止BMP4前域磷酸化的突变会损害同源二聚体的蛋白水解成熟,导致小鼠早期死亡。 Kim, H.-s. PDF N/A Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to early lethality in mice
一种针对鲍曼不动杆菌的新型烈性噬菌体:在小鼠肺部感染模型中的疗效和安全性 Wang, J. PDF N/A A Novel Genus of Virulent Phage Targeting Acinetobacter baumannii: Efficacy and Safety in a Murine Model of Pulmonary Infection
表观基因组的趋同进化在生命之树中招募了DNA修复 Monroe, G. PDF N/A Convergent evolution of epigenome recruited DNA repair across the Tree of Life
人类抗体识别的流感H1和H3血凝素上的保守位点 Maurer, D. P. PDF N/A Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies
从光栅响应构建的编码流形在皮层视觉区域中组织了对自然场景的响应 Dyballa, L. PDF N/A Encoding manifolds constructed from grating responses organize responses to natural scenes in cortical visual areas
后顶叶皮层介导了由稀有性引发的决策偏差以及在不确定性下的学习过程。 Sheng, W. PDF N/A Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty
C9orf72扩展导致不稳定的叶酸敏感脆弱位点FRA9A的形成。 Mirceta, M. PDF N/A C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A
类噬菌体CRISPR样调控RNA沉默细菌的适应性和先天免疫 Liu, C. PDF N/A Phage CRISPR-like regulatory RNAs silence bacterial adaptive and innate immunity
简化胎鼠影像中的不对称量化:基于专家指导的半自动化流程 Rolfe, S. M. PDF N/A Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance
Q_ST--F_ST比较中的错误率取决于遗传结构和估计程序 Liu, J. J. PDF N/A Error rates in Q_ST--F_ST comparisons depend on genetic architecture and estimation procedures
通过全基因组比较谱系地理学揭示的新热带山地与低地鸟类显著的种内多样化动态差异 Wacker, K. S. PDF N/A Distinct intraspecific diversification dynamics in Neotropical montane versus lowland birds revealed by whole-genome comparative phylogeography
基因组学和抗性检测有助于管理两种遭受入侵性桃金娘锈病病原体严重破坏的树种 Chen, S. H. PDF N/A Genomics and resistance assays inform the management of two tree species being devastated by the invasive myrtle rust pathogen
在严重肺炎链球菌肺炎的小鼠模型中,中性粒细胞转录组分化为两条截然不同的轨迹 Pihl, R. M. F. PDF N/A Neutrophil transcriptome diverges into two discrete trajectories in a murine model of severe Streptococcus pneumoniae pneumonia
Lowe综合征中神经发生缺陷是由线粒体丢失和与纤毛相关的音猬因子缺陷引起的。 Lo, C. PDF N/A Defective Neurogenesis in Lowe Syndrome is Caused by Mitochondria Loss and Cilia-related Sonic Hedgehog Defects
补偿性进化以应对DNA复制压力对营养物质的可用性具有鲁棒性 Natalino, M. PDF N/A Compensatory Evolution to DNA Replication Stress is Robust to Nutrient Availability
GDF5的复杂调控相互作用塑造了关节形态和骨关节炎疾病风险 Coveney, C. R. PDF N/A Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk
人乙型肝炎病毒向新热带野生灵长类动物的跨物种传播 boubli, J. PDF N/A Cross-species transmission of human hepatitis B virus to wild Neotropical primates
高通量、多重定量及单分子水平上的单个外泌体分选 Park, J. PDF N/A High-throughput, multiplexed quantification, and sorting of single EVs at single-molecule level
用于单细胞数据整合的图正则化最优传输 Wang, Z. PDF N/A Graph-Regularized Optimal Transport for Single-Cell Data Integration
使用可交换的寡核苷酸标签实现高吞吐量的单分子显微镜,具有可调节的空间分辨率 de Zwaan, K. PDF N/A High-throughput single molecule microscopy with adaptable spatial resolution using exchangeable oligonucleotide labels
左星状神经节与右星状神经节神经元的电生理比较 Verkerk, A. O. PDF N/A Electrophysiological comparison of left versus right stellate ganglia neurons
单细胞、空间和命运图谱分析揭示了耳蜗髓系细胞的微环境依赖性多样性。 Chiot, A. PDF N/A Single-cell, spatial, and fate-mapping analyses uncover niche dependent diversity of cochlear myeloid cells.
夏威夷短尾鱿鱼早期阶段对海洋变暖和酸化的发育及转录组反应 Otjacques, E. PDF N/A Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification
通过动力学限制的溶液相索引技术,实现了快速、简便且无需仪器的单细胞转录组分析 Marafini, P. PDF N/A Solution-phase indexing by kinetic confinement enables rapid, simple, and instrument-free single cell transcriptional profiling
癌症基金会:一种单细胞RNA测序基础模型,用于解析癌症中的药物抗性 Theus, A. PDF N/A CancerFoundation: A single-cell RNA sequencing foundation model to decipher drug resistance in cancer
MAPK信号通路调控植物细胞中DCP1在P-体与应激颗粒间的分配 He, S.-L. PDF N/A MAPK signaling modulates the partition of DCP1 between P-bodies and stress granules in plant cells
植物内化学防御的变异并不能解释小菜蛾对Erysimum cheiranthoides的取食偏好。 Zuest, T. PDF N/A Within-plant variation in chemical defence of Erysimum cheiranthoides does not explain Plutella xylostella feeding preference
稀有物种对高山植物群落系统发育多样性的贡献并不不成比例 Veldhuisen, L. N. PDF N/A Rare species do not disproportionately contribute to phylogenetic diversity in a subalpine plant community
四个ZIP基因在根的外部区域参与了锌、铁、铜和锰的吸收过程。 ROBE, K. PDF N/A Four ZIPs contribute to Zn, Fe, Cu and Mn acquisition at the outer root domain
一种超保守的ARF-DNA界面是生长素触发的转录反应的基础 Rienstra, J. PDF N/A An ultra-conserved ARF-DNA interface underlies auxin-triggered transcriptional response
确保科学研究的稳健性:以分根实验为例 Salvatore, L. PDF N/A Ensuring Robustness in Scientific Research, Split-root assays as an example case
早期分支蓝藻Anthocerotibacter panamensis中光系统I的结构与演化 Jiang, H.-W. PDF N/A Structure and evolution of Photosystem I in the early-branching cyanobacterium Anthocerotibacter panamensis
SOQ1 在拟南芥叶绿体液泡中作为甲硫氨酸亚砜还原酶,用于调节光保护性 qH。 Hao, J. PDF N/A SOQ1 functions as a methionine sulfoxide reductase in the chloroplast lumen for regulation of photoprotective qH in Arabidopsis
复杂鞘脂类在藓类植物小立碗藓的细胞分裂和质膜孔形成中起着至关重要的作用。 Wegner, L. PDF N/A Complex sphingolipids are essential for cell division and plasmodesmal development in the moss Physcomitrium patens
大豆种子产量、蛋白质和油脂的基因组和表型预测 Van der Laan, L. PDF N/A Genomic and Phenomic Prediction for Soybean Seed Yield, Protein, and Oil
特定物种叶际对外部pH变化的响应 Lopez Gonzalez, C. PDF N/A Species-specific phyllosphere responses to external pH change
动物RNA病毒的基因组大小反映了系统发育的限制 Takada, K. PDF N/A Genome sizes of animal RNA viruses reflect phylogenetic constraints
通过导管感染H5N1亚型2.3.4.4b流感病毒 Roubidoux, E. K. PDF N/A Intraductal infection with H5N1 clade 2.3.4.4b influenza virus
来自印度恒河原始河段的新型Tequatrovirus噬菌体在减少污水细菌负荷中的特性研究 Samson, R. PDF N/A Characterization of a Novel Tequatrovirus Phage from Pristine Stretch of The Ganges River, India, in Reducing Bacterial Load from Sewage Water
抑制鞭毛钩中赖氨酰丙氨酸交联的物质作为抗螺旋体微生物 Lynch, M. J. PDF N/A Inhibitors of lysinoalanine crosslinking in the flagella hook as antimicrobials against spirochetes
微生物裂解物作为细胞农业培养基配方中的低成本血清代用品 Dolgin, J. PDF N/A Microbial lysates as low-cost serum replacements in cellular agriculture media formulation
AnnotIEM:基于16S基因微生物测序的微生物组物种水平注释新工具 Bhatttacharyya, M. PDF N/A AnnotIEM: novel tool for microbiome species-level annotation of 16S gene based microbial sequencing
乳腺肿瘤微生物群调节抗肿瘤免疫和T细胞相关代谢物 Liu, C.-C. PDF N/A Breast tumor microbiome regulates anti-tumor immunity and T cell-associated metabolites
水稻植株中干旱诱导的活性氧调节与对黄单胞菌感染的抗性之间的相声 Ramu, D. S. PDF N/A Crosstalk Between Drought-Induced ROS Regulation and Resistance to Xanthomonas oryzae Infection in Rice Plants
独脚金内酯参与促进玉米对铁的吸收 Fili, S. PDF N/A Strigolactones are involved in enhancing iron uptake in maize
通过多模态方法表征高粱和亚麻荠对环境胁迫的响应 Seitz, K. A. PDF N/A Characterizing the Responses of sorghum and Camelina to Environmental Stress through a Multi-Modal Approach
通过Ca2+传感器调控TIR信号传导,激活ADR1对pRib-AMP-EDS1-PAD4的识别,从而启动气孔免疫机制。 Wang, H. PDF N/A Switch of TIR signaling by a Ca2+ sensor activates ADR1 recognition of pRib-AMP-EDS1-PAD4 for stomatal immunity
利用多环境试验育种数据优化基因型特异性参数评估木薯作物生长模型 Okoma, P. M. PDF N/A Evaluating a Cassava Crop Growth Model by Optimizing Genotypic-Specific Parameters Using Multi-environment Trial Breeding Data
调控玉米杂交种中异交相关基因表达互补的机制 Pitz, M. PDF N/A Regulation of heterosis-associated gene expression complementation in maize hybrids
广泛分布的野生植物在陡峭气候梯度下配子体性状对热胁迫的适应与驯化 Tushabe, D. PDF N/A Adaptation and acclimation of gametophytic traits to heat stress in a widely distributed wild plant along a steep climatic gradient
光温巧合检测器的遗传结构 Seluzicki, A. PDF N/A Genetic architecture of a light-temperature coincidence detector
数学模型指导最佳杀菌剂使用,以防治大豆菌核茎腐病,从而最大化大豆生产利润。 Byer, T. PDF N/A A mathematical model informs optimal fungicide use against Sclerotinia stem rot to maximize profits in soybean production
豆科(蝶形花亚科)植物中一些重要特征的可能多重起源 Aygoren Uluer, D. PDF N/A POSSIBLE MULTIPLE ORIGINS OF SOME IMPORTANT CHARACTERISTICS OF THE KEEL (PAPILIONATE) FLOWERS WITHIN FABALES
拟南芥SUFB和CLP蛋白酶调控SUFBC2D以操控叶绿体中铁硫簇的生物合成 Cheng, Y. PDF N/A Arabidopsis SUFB and CLP protease regulate SUFBC2D to manipulate iron-sulfur cluster biosynthesis in chloroplast
LysR型转录因子PacR在调控Anabaena sp. PCC7120氮代谢中的作用 Werner, E. PDF N/A The role of the LysR-type transcription factor PacR in regulating nitrogen metabolism in Anabaena sp. PCC7120
异戊二烯通过启动植物激素反应来驱避食草昆虫。 Sahu, A. PDF N/A Isoprene deters insect herbivory by priming plant hormone responses
通过一个结构化的跨专业培训项目,提升护理人员管理1型糖尿病患儿的能力 Juhi, A. PDF N/A Building capacity among caregivers for managing children with Type 1 Diabetes Mellitus through a structured Interprofessional training program
基于网络的表征学习揭示了时间和饮食对婴儿肠道微生物和代谢环境的影响 Price, A. PDF N/A Network-based representation learning reveals the impact of time and diet on the gut microbial and metabolomic environment of infants
锌能增强一种反翻译抑制剂的效力,这种抑制剂能杀死结核分枝杆菌和非结核分枝杆菌。 Varshney, A. PDF N/A A trans-translation inhibitor is potentiated by zinc and kills Mycobacterium tuberculosis and non-tuberculous mycobacteria
一种需要用于粘细菌胆固醇生产的香叶基香叶基还原酶同源物 Lee, A. K. PDF N/A A geranylgeranyl reductase homolog required for cholesterol production in Myxococcota
胶原蛋白结合粘附素限制金黄色葡萄球菌皮肤感染 Bhattacharya, M. PDF N/A Collagen binding adhesin restricts Staphylococcus aureus skin infection
在阿根廷恩特雷里奥斯省瓜莱瓜伊丘市患有阴道念珠菌病的育龄女性患者中分离出的念珠菌种 Perez Duarte, I. R. PDF N/A Candida species isolated in female patients of reproductive age with vaginal candidiasis in Gualeguaychu, Entre Rios, Argentina
使用BONCAT解析金黄色葡萄球菌持久性菌株的蛋白质组 George Matlalcuatzi, E. D. C. PDF N/A Using BONCAT To Dissect The Proteome Of S. aureus Persisters
特定连接泛素化靶向破坏揭示了K29连接泛素化在表观基因组完整性中的关键作用 Arroyo-Gomez, J. PDF N/A Targeted disruption of linkage-specific ubiquitylation reveals a key role of K29-linked ubiquitylation in epigenome integrity
利用固定在无人驾驶飞行器上的轻便便携式空气采样器检测加州中央谷地空气中的球孢子菌孢子 Radosevich, M. T. PDF N/A Detection of airborne Coccidioides spores using lightweight portable air samplers affixed to uncrewed aircraft systems in California's Central Valley
PAL-AI揭示了在卵母细胞成熟过程中控制多聚腺苷酸尾长度的遗传决定因素,这些因素与人类生育能力相关。 Xiang, K. PDF N/A PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation with relevance to human fertility
研究短链脂肪酸对结直肠癌中细胞外囊泡生成的影响 Macedo, D. PDF N/A Investigating Short-Chain Fatty Acids Effects on Extracellular Vesicles Production in Colorectal Cancer
陆地蛞蝓Ambigolimax valentianus的耐寒性 Gill, L. T. PDF N/A The cold tolerance of the terrestrial slug, Ambigolimax valentianus
适应毒物的北大西洋青鳉鱼(Fundulus heteroclitus)在低氧条件下基因表达和DNA甲基化变化 Aluru, N. PDF N/A Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus)
人类巨噬细胞反应与L. (V.) panamensis对五价锑的自然抗性之间的相互作用 Fernandez, O. L. PDF N/A Interplay of human macrophage response and natural resistance of L. (V.) panamensis to pentavalent antimony
胚胎肥大细胞来源于表达Cpa3的祖细胞,与粒细胞-单核细胞祖细胞无关 Ma, W. PDF N/A Embryonic Mast Cells Arise from Cpa3-expressing Precursors Independent of Granulocyte-Monocyte Progenitors
一个PI3Kδ-Foxo1-FasL信号放大环路重新编排了CD4+辅助T细胞的信号传导、分化和表观遗传重塑 Golec, D. P. PDF N/A A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T helper cell signaling, differentiation and epigenetic remodeling
灵活的、适用于生产规模的、在台式测序仪上进行的人类全基因组测序 Green, K. PDF N/A FLEXIBLE, PRODUCTION-SCALE, HUMAN WHOLE GENOME SEQUENCING ON A BENCHTOP SEQUENCER
绘制人类结肠肠内分泌细胞所显示的可成药靶点 Lei, Y. PDF N/A Mapping the druggable targets displayed by human colonic enteroendocrine cells
竞争、降水和温度塑造了miombo林冠异速生长律偏离缩放定律的形态 Yambayamba, A. M. PDF N/A Competition, precipitation and temperature shape deviations from scaling laws in the crown allometries of miombo woodlands
按蚊幼虫在水生生态系统中的营养相互作用:一种宏基因组学方法 Karikari, A. S. PDF N/A Trophic Interactions of Anopheles Gambiae Mosquito Larvae in Aquatic Ecosystem: A Metagenomics Approach
从图分析中得出的功能性重要残基:协同进化动态耦合 Xu, M. PDF N/A Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings
栽培啤酒花(Humulus lupulus L.)的进化历史及其根际微生物群落组成 McElwee-Adame, A. PDF N/A Evolutionary history and rhizosphere microbial community composition in domesticated hops (Humulus lupulus L.)
黑腹果蝇利用核结构来招募剂量补偿机制。 Sneideman, M. P. L. PDF N/A Drosophila melanogaster employs nuclear architecture for recruitment of dosage compensation
组蛋白变体H2BE调控活动依赖性基因表达及稳态缩放 Feierman, E. R. PDF N/A Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling
通过建模基因型与环境互作进行花生产量的基因组预测 Lubanga, N. PDF N/A Genomic prediction by modelling genotype by environment interaction for yield in groundnut
核苷酸自组装的病理生理学意义:腺嘌呤衍生核苷酸在疾病机制中的聚集 Dave, R. PDF N/A Pathophysiological Implications of Nucleotide Self-Assembly: Adenine-Derived Nucleotides Aggregation in Disease Mechanisms
多层次牙型多样性的整合将鲨鱼宏观进化模式与生态策略联系起来。 Zimm, R. PDF N/A Integration of multi-level dental diversity links macro-evolutionary patterns to ecological strategies across sharks.
早期区域淋巴结激活可驱动祖先多样性人群中的流感疫苗反应 Siu, J. H. PDF N/A Early regional lymph node activation drives influenza vaccine responses in an ancestrally diverse cohort
PIPENN-EMB:集成网络与蛋白质嵌入超越同源性推广蛋白质界面预测 Thomas, D. P. G. PDF N/A PIPENN-EMB: ensemble net and protein embeddings generalise protein interface prediction beyond homology
在非靶向代谢组学中,是否进行缺失值填补——这就是组成性问题 Krutkin, D. D. PDF N/A To impute or not to impute in untargeted metabolomics - that is the compositional question
癌症突变互斥性的贝叶斯建模 Czyz, P. PDF N/A Bayesian modeling of mutual exclusivity in cancer mutations
PSTP:通过迁移学习和注意力机制解码蛋白质相分离的潜在序列语法 Feng, M. PDF N/A PSTP: Decoding Latent Sequence Grammar through Transfer Learning and Attention for Protein Phase Separation
生成低密度最小化器 Golan, S. PDF N/A Generating low-density minimizers
通过多模态深度学习预测细菌蛋白质功能 Muzio, G. PDF N/A Bacterial protein function prediction via multimodal deep learning
通过链统计提高泛基因组分类准确性 Brown, N. K. PDF N/A Improved pangenomic classification accuracy with chain statistics
缺氧诱导胰腺腺癌(PDAC)细胞系细胞表面的广泛蛋白质和蛋白水解重塑 Lui, I. PDF N/A Hypoxia induces extensive protein and proteolytic remodeling of the cell surface in pancreatic adenocarcinoma (PDAC) cell lines
靶向PTP4A3的过度表达可增强HGSOC细胞对化疗药物的敏感性。 Lopez-Garza, A. PDF N/A Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs.