| 脊髓兴奋性增加导致运动复杂性降低 |
de Graaf, M. L. |
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N/A |
Increased spinal excitation causes decreased locomotor complexity |
| 婴儿低频脑电皮层功率、皮层追踪和相位振幅耦合预测一年后的语言能力。 |
Attaheri, A. |
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N/A |
Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later. |
| 在真菌发病过程中，铁死亡的一种新型线粒体调节网络 |
Shen, Q. |
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N/A |
A novel mitochondrial regulon for Ferroptosis during fungal pathogenesis |
| 一统天下？评估可持续森林管理指标对多分类群数据在生物多样性保护中的表现 |
Paillet, Y. |
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N/A |
One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation |
| 光敏素将绿藻中的蓝光感知与淀粉代谢联系起来 |
Yuan, Y. |
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N/A |
Phototropin connects blue light perception to starch metabolism in green algae |
| 逐次检测神经时间序列中的认知事件 |
Weindel, G. |
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N/A |
Trial-by-trial detection of cognitive events in neural time-series |
| 从BioModels中筛选模型：开发创建OMEX文件的工作流程 |
Xu, J. |
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N/A |
Curating models from BioModels: Developing a workflow for creating OMEX files |
| 一段涉及多个P450基因的基因组重复有助于登革热蚊子埃及伊蚊的杀虫剂抗性。 |
Bacot, T. |
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N/A |
A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti |
| 将心率与自我-社交触摸区分中涉及的皮层网络动态相联系 |
Candia-Rivera, D. |
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N/A |
Linking heartbeats with the cortical network dynamics involved in self-social touch distinction |
| ARTEM：一种用于识别RNA和DNA三级基序的方法，包括骨架排列，并举例应用于类扭结转角基序 |
Baulin, E. F. |
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N/A |
ARTEM: a method for RNA and DNA tertiary motif identification with backbone permutations, and its example application to kink-turn-like motifs |
| 使用重组脱氧核糖核酸酶I治疗抗髓过氧化物酶肾小球肾炎，通过腺相关病毒基因疗法得到增强 |
Cao Le, A. |
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N/A |
Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy |
| 空间转录组学基因表达框架 |
Cao, S. |
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N/A |
A framework for gene representation on spatial transcriptomics |
| 强迫性与适应性应对策略的肾上腺素能和巴甫洛夫基础 |
Chernoff, C. S. |
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N/A |
Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies |
| FoldMark：通过水印技术保护蛋白质生成模型 |
ZHANG, Z. |
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N/A |
FoldMark: Protecting Protein Generative Models with Watermarking |
| 偏倚校正元分析克服小脑忽视，以完善小脑行为地形图 |
Magielse, N. |
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N/A |
Bias-accounting meta-analyses overcome cerebellar neglect to refine the cerebellar behavioral topography |
| 父母谈判策略演变中衍生出的替代后代抚养模式的出现 |
Zheng, J. |
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N/A |
Emergence of alternative offspring care patterns from the evolution of parental negotiation strategies |
| 进化上较近的转录因子参与人类细胞周期的调控 |
Pulver, C. |
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N/A |
Evolutionarily recent transcription factors partake in human cell cycle regulation |
| 调控转录因子（TF）-DNA相互作用的比较和群体基因组学分析 |
Joshi, M. |
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N/A |
Comparative and population genomics analyses of the regulatory Transcription Factor (TF)-DNA interaction |
| 多样化的祖先代表性改善了遗传不耐受度量 |
Han, A. |
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N/A |
Diverse ancestral representation improves genetic intolerance metrics |
| 单变量与多变量参考区间方法的比较 |
MERGEN, E. K. |
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N/A |
COMPARISON OF UNIVARIATE AND MULTIVARIATE REFERENCE INTERVAL METHODS |
| 用于复杂异质性单细胞数据的标记基因捕捞 |
Shao, Y. |
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N/A |
Marker gene fishing for single-cell data with complex heterogeneity |
| 未能考虑RNA数量会导致背景升高，并导致PRC2和GFP在体内结合RNA的误导性表象。 |
Guo, J. K. |
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N/A |
Failing to account for RNA quantity inflates background and leads to the misleading appearance that PRC2 and GFP bind to RNA in vivo |
| 解码肝癌预后：从多组学亚型、预后模型到单细胞验证 |
Wang, Y. |
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N/A |
Decoding Liver Cancer Prognosis: From Multi-omics Subtypes, Prognostic Models to Single Cell Validation |
| 复杂性和孟德尔性状中的多效性决定因素及其进化后果 |
Barbitoff, Y. A. |
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N/A |
Functional determinants and evolutionary consequences of pleiotropy in complex and Mendelian traits |
| 利用可扩展的方法恢复和维持人类死后视网膜的光反应，以测试退行性疾病疗法 |
Becker, S. |
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N/A |
Restoring and sustaining human postmortem retinal light responses with scalable methods for testing degenerative disease therapies |
| 酒精依赖戒断的神经标志物：来自奖励学习的启示 |
Komarnyckyj, M. |
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N/A |
Neural markers of abstinence in alcohol dependence: Insights from Reward Learning |
| 两个H3K23组蛋白甲基转移酶，SET-32和SET-21，协同作用以促进在秀丽隐杆线虫中通过核RNAi介导的跨代表观遗传继承。 |
Gu, S. G. |
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N/A |
Two H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote nuclear RNAi-mediated transgenerational epigenetic inheritance in Caenorhabditis elegans |
| 两种H3K23组蛋白甲基转移酶，SET-32和SET-21，在秀丽隐杆线虫中协同作用，促进核RNAi介导的跨代表观遗传继承。 |
Gu, S. G. |
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N/A |
Two H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote nuclear RNAi-mediated transgenerational epigenetic inheritance in Caenorhabditis elegans |
| 孕期补充益生菌对健康人群是否安全？一项针对临床前研究的系统综述 |
COCA, M. R. |
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N/A |
Is Probiotic Supplementation During Pregnancy Safe for Healthy Populations? A Systematic Review of Preclinical Studies |
| 神经元检测触发全身消化系统关闭，以应对不良食物来源 |
Liu, Y. |
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Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources |
| 从开花期到高温耐受性：PHOTOPERIOD 1（PPD-H1）通过提高高温环境下的抗逆性和能量代谢来调控穗部结实率 |
Lan, T. |
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N/A |
From Flowering Time to High Temperature Resilience: PHOTOPERIOD 1 (PPD-H1) Controls Spike Fertility through Improving Stress Resistance and Energy Metabolism under High Ambient Temperatures |
| 陆生植物特异的H3K27甲基转移酶ATXR5和ATXR6调控植物发育及胁迫响应 |
Li, X. |
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Land plant-specific H3K27 methyltransferases ATXR5 and ATXR6 control plant development and stress responses |
| 实时闭环反馈系统用于小鼠中尺度皮层信号与运动控制：CLoPy |
Gupta, P. K. |
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Real-Time Closed-Loop Feedback System For Mouse Mesoscale Cortical Signal And Movement Control: CLoPy |
| 巨噬细胞-平滑肌细胞轴通过激活EGFR途径影响大细胞性动脉炎中的血管重塑 |
Chevalier, K. |
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N/A |
A macrophage-smooth muscle cell axis influences vascular remodeling through activation of the EGFR pathway in giant cell arteritis |
| 淋巴细胞减少促使T细胞衰竭在免疫缺陷STING功能获得性小鼠中 |
Freytag, D. |
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N/A |
Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice |
| 用于体外流感气溶胶暴露的气液界面模型 |
Seibert, B. |
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N/A |
Air-Liquid Interface Model for Influenza Aerosol Exposure In Vitro |
| 血液点卡上动物粪便材料的DNA提取方案 |
Llarena, A.-K. |
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N/A |
DNA Extraction Protocols for Animal Fecal Material on Blood Spot Cards |
| 通过液相色谱-串联质谱（LC-MS/MS）对mRNA中的N6-甲基腺苷和肌苷进行全球分析揭示了复杂的分布情况。 |
Stejskal, S. |
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N/A |
Global Analysis by LC-MS/MS of N6-Methyladenosine and Inosine in mRNA Reveals Complex Incidence |
| 双CRISPR干扰策略用于靶向癌细胞中非编码RNA之间的合成致死相互作用 |
Schlosshauer, J. J. |
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N/A |
Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions between Non-Coding RNAs in Cancer Cells |
| Vcfexpress：灵活、快速的过滤和格式化VCF的用户表达式 |
Pedersen, B. S. |
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N/A |
Vcfexpress: flexible, rapid user-expressions to filter and format VCFs |
| 预测肿瘤突变负荷从超高频介电泳交叉频率 |
Daverat, H. |
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N/A |
Predicting Tumor Mutational Burden from UHF-Dielectrophoresis Crossover Frequency |
| CD3、CD4和CD8的染色结果与亚洲乳腺癌患者的总体生存呈正相关，而PD-L1则不然。 |
Pan, J.-W. |
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N/A |
CD3, CD4, and CD8 staining, but not PD-L1, are positively correlated with overall survival in Asian breast cancer |
| DNA甲基化是转移性肾细胞癌中靶向治疗和免疫检查点治疗反应的关键决定因素。 |
Jeanneret, F. |
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N/A |
DNA methylation is a key determinant of response to targeted and immune checkpoint therapies in metastatic renal cell carcinoma |
| 解析油菜开花时间变异的分子基础 |
Zhang, L. |
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N/A |
Dissecting the molecular basis of variability for flowering time in Camelina sativa |
| R-Loop的调控与线粒体基因组的稳定性需要5'-3'外切核酸酶/盖帽内切核酸酶OEX1的参与。 |
Schatz-Daas, D. |
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N/A |
R-Loop control and mitochondria genome stability requires the 5'-3' exonuclease/flap-endonuclease OEX1 |
| 利用大型语言模型推进植物代谢研究：扩展数据库并提取标注数据 |
Knapp, R. |
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N/A |
Advancing Plant Metabolic Research By Using Large Language Models To Expand Databases And Extract Labelled Data |
| 标注冷冻电镜断层成像体积：一项机器学习挑战 |
Peck, A. |
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N/A |
Annotating CryoET Volumes: A Machine Learning Challenge |
| 雌性蛾类将植物声学信号纳入其产卵决策中 |
Seltzer, R. |
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N/A |
Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision |
| 利用CFD建模描述叶轮设计对植物细胞发酵的影响 |
Manickavasagam, V. M. |
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N/A |
Characterizing the effect of impeller design in plant cell fermentations using CFD modeling |
| 磷酸酶PP2C12是LRX-RALF-FER介导的细胞壁完整性感知中的负调控因子。 |
Hou, X. |
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N/A |
The phosphatase PP2C12 is a negative player in LRX-RALF-FER-mediated cell wall integrity sensing |
| 基质利用和交叉喂养协同作用决定了微生物群对病原体入侵的抵抗力 |
Yang, X. |
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N/A |
Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion |
| 在脆性X模型中，重复扩展与由Pol θ、Rad52、Rad54l或Rad54b介导的双链断裂修复无关。 |
Hayward, B. E. |
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N/A |
Repeat expansion in a Fragile X model is independent of double strand break repair mediated by Pol θ, Rad52, Rad54l or Rad54b |
| 细胞生长的几何平衡模型 |
Vazquez, A. |
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N/A |
Geometrically balanced model of cell growth |
| 神经血管完整性与衰老中液体运输的关系：一项多模态神经影像学研究 |
Rowsthorn, E. |
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N/A |
Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study |
| 皮层生长抑素中间神经元对神经血管耦合的双向调控 |
Mohamed, B. |
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N/A |
Bidirectional control of neurovascular coupling by cortical somatostatin interneurons |
| 同时诱发的慢伽马波和快伽马波在灵长类动物初级视觉皮层中独立传播 |
Gautham, B. K. |
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N/A |
Simultaneously induced slow and fast gamma waves travel independently in primate primary visual cortex |
| AAV载体中微RNA靶序列排列的优化显著增强了皮层小胶质细胞中转基因表达的特异性和效率 |
Aoki, R. |
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N/A |
Optimization of microRNA Target Sequence Arrangement in AAV Vectors Dramatically Enhances Specificity and Efficiency of Transgene Expression in Cortical Microglia |
| RAB GTP酶的邻近图谱 |
Gaudreault St-Laurent, V. |
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N/A |
A Proximity MAP of RAB GTPases |
| 一种用于蓝钟虫单细胞习惯化的受体失活模型 |
Rajan, D. H. |
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N/A |
A receptor-inactivation model for single-celled habituation in Stentor coeruleus |
| ANKZF1通过LC3介导的线粒体自噬帮助消除应激损伤的线粒体。 |
Ali, M. |
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N/A |
ANKZF1 helps to eliminate the stress-damaged mitochondria by LC3-mediated mitophagy |
| AMP激活蛋白激酶对网格蛋白介导的内吞作用的货物选择性调节 |
Orofiamma, L. A. |
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N/A |
Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase |
| 一种用于钙的绿色终身生物传感器，其亮度在其整个动态范围内保持稳定 |
van der Linden, F. H. |
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N/A |
A green lifetime biosensor for calcium that remains bright over its full dynamic range |
| CDR2是一种动力蛋白适配器，被kinectin招募来调节内质网片的组织结构。 |
Teixeira, V. |
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N/A |
CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization |
| 使用spoon处理空间分辨转录组数据中的均值-方差关系 |
Shah, K. H. |
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N/A |
Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon |
| 光依赖的黄素氧化还原和加合物状态调控转录因子EL222的构象和DNA结合活性 |
Chaudhari, A. S. |
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N/A |
Light-dependent flavin redox and adduct states control the conformation and DNA binding activity of the transcription factor EL222 |
| 利用带正电荷的可生物降解纳米材料实现体外和体内的mRNA高效递送 |
Yang, X. |
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N/A |
Efficient mRNA Delivery In Vitro and In Vivo Using a Polycharged Biodegradable Nanomaterial |
| 通过免疫信息学和计算表位预测设计Mpox疫苗 |
Rivera-Orellana, S. |
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N/A |
Mpox Vaccine Design Through Immunoinformatics and Computational Epitope Prediction |
| VirNA：一种用于研究病毒演化的新型最小生成网络算法 |
Mazzotti, G. |
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N/A |
VirNA: a novel Minimum Spanning Networks algorithm for investigating viral evolution |
| 新冠病毒疾病（COVID）后疲劳持续超过12周与基于努力的决策过程中奖励敏感性降低相关。 |
Scholing, J. M. |
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N/A |
Fatigue >12 weeks after coronavirus disease (COVID) is associated with reduced reward sensitivity during effort-based decision making |
| 综合宏基因组学和代谢组学揭示了实验性COVID-19中与年龄相关的肠道微生物群和代谢物改变 |
Rodrigues, P. B. |
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N/A |
Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in experimental COVID-19 |
| 纳米颗粒支持的快速数字化量化针对SARS-CoV-2变种的中和抗体 |
Mirjalili, S. |
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N/A |
Nanoparticle-Supported, Rapid, Digital Quantification of Neutralizing Antibodies Against SARS-CoV-2 Variants |
| BNT162b2 JN.1和KP.2适应型COVID-19疫苗的免疫学和生物物理特性 |
Chen, W. |
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N/A |
Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines |
| 利用铜绿假单胞菌荧光绿脓菌素色素开发发光塑料砖 |
Pandey, K. |
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N/A |
Development of glowing plastic bricks from waste plastic and florescent pyoverdine pigment of Pseudomonas aeruginosa |
| 抗非生长和胞内细菌的抗菌化合物 |
Kaldalu, N. |
PDF |
N/A |
Antibacterial Compounds Against Non-Growing and Intracellular Bacteria |
| 一个可访问的3D HepG2/C3A肝球体模型，支持恶性疟原虫在肝细胞内的完整生命周期 |
Alqurashi, S. O. |
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N/A |
An Accessible 3D HepG2/C3A Liver Spheroid Model Supporting the Complete Intrahepatocytic Lifecycle of Plasmodium falciparum |
| 微生物学与人类学：在澳大利亚新南威尔士州农村冬季估计死亡时间的多学科方法。 |
Green, H. |
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N/A |
Microbiology and Anthropology: a multidisciplinary approach for estimating time since death during Winter in rural New South Wales, Australia. |
| Lrp1促进Jamestown Canyon病毒对神经元的感染 |
Frey, Z. D. |
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N/A |
Lrp1 facilitates infection of neurons by Jamestown Canyon virus |
| 牛瘤胃中大肠杆菌O26:H11、O111:H8和O145:NM血清型的生长动力学及蛋白质表达。 |
Kudva, I. T. |
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N/A |
Growth dynamics and protein-expression of Escherichia coli serotypes O26:H11, O111:H8 and O145:NM in the bovine rumen. |
| 增强的胞外基质生成对无细胞壁的大肠杆菌提供了保护作用。 |
Crooijmans, M. E. |
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N/A |
Enhanced extracellular matrix production provides protection to cell wall-deficient Escherichia coli |
| 与侵染红松的树皮甲虫相关的长喙壳科真菌，包括在中国发现的新种Ceratocystiopsis fushunensis的描述。 |
Ran, Y. |
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N/A |
Ophiostomatalean fungi associated with bark beetles infesting Pinus koraiensis, including the description of Ceratocystiopsis fushunensis sp. nov. in China |
| 病毒样博格古菌染色体外元素与巨型真核病毒的趋同进化 |
Banfield, J. |
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N/A |
Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses |
| 通过一种创新的喷枪技术，证明了海洋环境相对于陆地环境缺乏功能性聚酯生物降解潜力。 |
Contreras-Moll, A. |
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N/A |
Lack of functional polyester-biodegrading potential in marine versus terrestrial environments evidenced by an innovative airbrushing technique |
| 细菌和真菌中的木质纤维素降解用于生物质转化 |
Hsin, K.-T. |
PDF |
N/A |
Lignocellulose Degradation in Bacteria and Fungi for Biomass Conversion |
| 通过元蛋白质组学评估水生关键物种在不同饮食下的关键肠道微生物组分和功能 |
Dumas, T. |
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N/A |
Key gut microbiota components and functions in an aquatic keystone species across diets assessed by metaproteomics |
| SCA2/ALS13小鼠模型脊髓磷酸蛋白质组揭示了ATXN2-N端SH3-肌动蛋白相互作用网络的改变，以及通过WNK1-MYO6-OPTN-SQSTM1途径的自噬调控异常 |
Almaguer-Mederos, L. E. |
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N/A |
Spinal cord phosphoproteome of a SCA2/ALS13 mouse model reveals alteration of ATXN2-N-term SH3-actin interactome and of autophagy via WNK1-MYO6-OPTN-SQSTM1 |
| MRAP2辅助蛋白直接与黑皮质素-3受体相互作用，以增强信号传导。 |
Jamaluddin, A. |
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N/A |
The MRAP2 accessory protein directly interacts with melanocortin-3 receptor to enhance signaling |
| 通过细胞间mRNA转移在体外互补人类疾病表型 |
Haimovich, G. |
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N/A |
Complementation of a human disease phenotype in vitro by intercellular mRNA transfer |
| 心脏重编程中的核小体重塑 |
Harris, S. |
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N/A |
Nucleosome repositioning in cardiac reprogramming |
| 人类及其他大猿类端粒到端粒基因组中G-四链体的进化动力学 |
Mohanty, S. K. |
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N/A |
Evolutionary Dynamics of G-Quadruplexes in Human and Other Great Ape Telomere-to-Telomere Genomes |
| 操纵IKZF1的可变剪接在T细胞中引发不同的基因调控反应 |
Pastor, L. |
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N/A |
Manipulation of alternative splicing of IKZF1 elicits distinct gene regulatory responses in T cells |
| 发现嵌合聚酮类家族作为癌症免疫原性化疗先导物 |
Xue, D. |
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N/A |
Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads |
| 由跨膜结构域结构可塑性调控的线粒体PINK1的替代进口通道和目的地 |
Lorriman, J. |
PDF |
N/A |
Alternative Import-Channels And Destinations Of Mitochondrial PINK1 Controlled By Trans-Membrane-Domain Structural Plasticity |
| 在驯养条件下，野生肠道微生物群抑制了斑马鱼体内的机会性病原菌——气单胞菌。 |
Kawano, K. |
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N/A |
Wild gut microbiome suppresses the opportunistic pathogen Aeromonas in medaka under domesticated rearing conditions |
| 保守的HIV-1间隔肽2触发基质晶格成熟 |
Stacey, J. C. V. |
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N/A |
The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation |
| 长链非编码RNA HSCHARME通过调控在人类心肌病中改变的基因调控网络，促进干细胞衍生心肌细胞的成熟。 |
Buonaiuto, G. |
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N/A |
Long noncoding RNA HSCHARME promotes the maturation of stem cells-derived cardiomyocytes by controlling gene regulatory networks altered in human cardiomyopathies |
| 与AMD相关的遗传多态性CFH Y402H使iPSC-RPE细胞对氢醌诱导的压力更为敏感。 |
Armento, A. |
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N/A |
The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells |
| 通过在Cas9介导的基因组编辑过程中短暂双重抑制TP53和DNA甲基化，高效重新激活女性hPSC中的XIST。 |
Motosugi, N. |
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N/A |
Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing |
| 在PYK2-null小鼠中，内皮细胞中可诱导的FAK缺失而非FAK抑制激活了p53，从而抑制肿瘤生长。 |
Chen, X. L. |
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N/A |
Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice |
| 全息显微镜揭示了在血管内皮化过程中，无需标记的内皮细胞定量动力学。 |
Leineweber, W. D. |
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N/A |
Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization |
| 磷脂信号和多泡内溶酶体调节稻瘟菌共生界面处的膜动态变化 |
Selvaraj, P. |
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N/A |
Phospholipid signaling and multivesicular endolysosomes modulate membrane dynamics at the biotrophic interface in Rice Blast |
| RING1 决定 GSDMD 介导的炎症反应及宿主对病原体感染的易感性 |
Li, Y. |
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N/A |
RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infection |
| 鸡和鼠神经嵴发育的比较分析 |
Kulesa, P. M. |
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N/A |
Comparative Analysis of Neural Crest Development in the Chick and Mouse |
| Wnt1-Cre2转基因会导致非神经嵴细胞类型的异常重组。 |
Gandhi, S. |
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N/A |
The Wnt1-Cre2 transgene causes aberrant recombination in non-neural crest cell types |
| 体外受精引发雄性小鼠后代的生殖变化，并具有多代效应。 |
Rhon-Calderon, E. A. |
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N/A |
In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects |
| EEMtoolbox：一个用户友好的R包，用于灵活的集成生态系统建模 |
Pascal, L. V. |
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N/A |
EEMtoolbox: A user-friendly R package for flexible ensemble ecosystem modeling |
| 轻踏海底：延绳钓陷阱和钓钩渔具的海底接触定量估算 |
Doherty, B. |
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N/A |
Treading lightly: Quantitative estimates of seafloor contact for longline trap and hook fishing gear |
| 自上而下的气候过程调节北美森林中的生物多样性与功能关系 |
Maluquer, X. S. |
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N/A |
TOP-DOWN CLIMATIC PROCESSES MODULATE BIODIVERSITY-FUNCTIONING RELATIONSHIPS ACROSS NORTH AMERICAN FORESTS |
| 鱼类研究的边界？伊塔蒂亚亚探险与生物多样性数据库揭示了巴西高海拔水生生态系统中鱼类分布的空白 |
Soares Guedes, G. H. |
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N/A |
A fish frontier? Itatiaia expedition and biodiversity repositories reveal gaps in fish occurrences in Brazil's high-altitude aquatic ecosystems |
| 湿度和竞争限制了埋葬甲繁殖的短暂资源质量 |
Hayes, T. E. |
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N/A |
Moisture and competition constrain ephemeral resource quality for burying beetle reproduction |
| 电鳐科（Narcinidae，Gill, 1862）电鳐的谱系地理学：系统回顾与美洲扩散路径的证据。 |
Rodrigues-Filho, L. F. S. |
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N/A |
Phylogeography of the electric rays of the family Narcinidae (Gill, 1862): systematic review and evidence of the dispersal routes to America. |
| 啤酒花中X-A平衡性决定系统的进化与功能 |
Akagi, T. |
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N/A |
Evolution and functioning of an X-A balance sex determination system in hops |
| 由自由基和类过氧桥相互作用驱动的TCA循环中的C-C键断裂与生成 |
Yang, L. |
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N/A |
C-C bond cleavage and generation in TCA cycle driven by radicals and peroxo-bridge like interaction |
| 开发新型可切割交联剂试剂用于细胞内交联的探索之旅 |
Mueller, F. |
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N/A |
A journey towards developing a new cleavable crosslinker reagent for in-cell crosslinking |
| AistSeq：一种基于Tn5的内部质粒测序平台，采用紧凑型台式测序仪 |
Suzuki, H. |
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N/A |
AistSeq: An In-House Tn5-Based Plasmid Sequencing Platform Using A Compact Benchtop Sequencer |
| 利用3D nnUnet和光片显微镜进行自动细胞追踪，以量化斑马鱼中的区域变形 |
Teranikar, T. A. |
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N/A |
Automated cell tracking using 3D nnUnet and Light Sheet Microscopy to quantify regional deformation in zebrafish |
| 血小板膜包覆的超顺磁性氧化铁纳米粒子用于癌症治疗中的靶向紫杉醇递送和磁热疗 |
Tavakoli, M. |
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N/A |
Platelet Membrane-Coated SPION for Targeted Paclitaxel Delivery and Magnetic Hyperthermia in Cancer Therapy |
| 金属离子对DNA纳米结构等温自组装的影响 |
Rodriguez, A. |
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N/A |
Influence of metal ions on the isothermal self-assembly of DNA nanostructures |
| SingleFrag：一种用于MS/MS片段和光谱预测及代谢物注释的深度学习工具 |
Perez-Ribera, M. |
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N/A |
SingleFrag: A deep learning tool for MS/MS fragment and spectral prediction and metabolite annotation |
| 多阶张量的统一分析用于综合分子特征分析 |
De Azevedo, K. |
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N/A |
Unified Analysis of Multi-order Tensors for Integrative Molecular Profiling |
| 通过剪接进化的视角增强转录组注释 |
Zang, X. C. |
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N/A |
Augmenting Transcriptome Annotations through the Lens of Splicing Evolution |
| Rthoptera：R语言中的标准化昆虫生物声学分析工具 |
Rivas, F. |
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N/A |
Rthoptera: standardized insect bioacoustics in R |
| 胡萝卜中的植物化学物质对三阴性乳腺癌PDK1和PLK1具有治疗潜力。 |
Raheem, k. |
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N/A |
Phytochemicals from Daucus carota have therapeutic potential against Triple-Negative Breast Cancer PDK1 and PLK1. |
| TomoPicker：冷冻电子断层扫描中的注释高效粒子挑选 |
Uddin, M. R. |
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N/A |
TomoPicker: Annotation-Efficient Particle Picking in cryo-electron Tomograms |
| G4-Attention：用于预测DNA G-四链体的带注意力机制的深度学习模型 |
Mukherjee, S. |
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N/A |
G4-Attention: Deep Learning Model with Attention for predicting DNA G-Quadruplexes |
| 阶段特异性基因比率突显了与无症状和有症状多发性骨髓瘤相关的基因和机制。 |
Georgiou, G. |
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N/A |
Stage-specific gene ratios highlight genes and mechanisms related to presymptomatic and symptomatic Multiple Myeloma |
| 单细胞分辨率下的转录组装配与海狸 |
Shi, Q. |
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N/A |
Transcriptome Assembly at Single-Cell Resolution with Beaver |
| PAIRWISE：基于深度学习的癌症个性化药物组合有效性预测 |
Xu, C. |
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N/A |
PAIRWISE: Deep Learning-based Prediction of Effective Personalized Drug Combinations in Cancer |
| Biosynth Pipeline：一个集成平台，用于将嵌合型I类聚酮合酶的计算设计与化学生物合成的酶促途径相结合 |
Chainani, Y. |
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N/A |
Biosynth Pipeline: An integrated platform for merging the computational design of chimeric type I polyketide synthases with enzymatic pathways for chemical biosynthesis |
| 单细胞转录组学揭示非酒精性脂肪肝疾病的基因组指标 |
Thakur, M. |
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N/A |
Single Cell Transcriptomics Reveal Genomic Indicators of Nonalcoholic Fatty Liver Disease |
| 用于冷冻电镜图像处理的全面基础模型 |
Yan, Y. |
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N/A |
A comprehensive foundation model for cryo-EM image processing |
| mcBERT：患者级单细胞转录组数据表示 |
Querfurth, B. v. |
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N/A |
mcBERT: Patient-Level Single-cell Transcriptomics Data Representation |
| 单细胞数据自监督学习的基准测试 |
Toma, P. |
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N/A |
Benchmarking Self-Supervised Learning for Single-Cell Data |
| 使用随机丙氨酸序列扫描结合AlphaFold2中的浅层子采样评估无配体和有配体蛋白质状态的结构与构象集合：对功能别构构象预测的见解与教训 |
Raisinghani, N. |
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N/A |
Assessing Structures and Conformational Ensembles of Apo and Holo Protein States Using Randomized Alanine Sequence Scanning Combined with Shallow Subsampling in AlphaFold2 : Insights and Lessons from Predictions of Functional Allosteric Conformations |
| 微管动态由聚类原丝的构象和稳定性所决定。 |
Kalutskii, M. |
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N/A |
Microtubule dynamics are defined by conformations and stability of clustered protofilaments |
| 酸性条件促进癌细胞来源的细胞外囊泡聚集，并增强其与合成脂质体的融合 |
Fisher, W. S. |
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N/A |
Acidic Conditions Promote Clustering of Cancer Cell Derived Extracellular Vesicles and Enhance their Fusion with Synthetic Liposomes |
| DNA序列对ZTA转录因子-DNA复合物的热力学和结构稳定性的影响：一项全原子分子动力学研究 |
Duraisamy, B. |
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N/A |
Influence of DNA sequences on thermodynamic and structural stability of ZTA transcription factor - DNA complex: An all-atom molecular dynamics study |
| 肌动蛋白周转和肌球蛋白收缩力决定了模拟细胞皮层的突现厚度鲁棒性 |
Gat, S. |
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N/A |
Actin turnover and myosin contractility determine emergent Thickness Robustness of Cell-Mimicking Cortex |
| 蛋白质动力学构成了热感受器对温度强烈依赖的基础 |
Qin, F. |
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N/A |
Protein Dynamics Underlies Strong Temperature Dependence of Heat Receptors |
| Tau-微管蛋白共凝聚物在早期微管组织中的结构化作用 |
Lee-Eom, C. |
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N/A |
Structuring Role of Tau-Tubulin Co-Condensates in Early Microtubule Organization |
| 神经肽Y在水溶液中的pH依赖性结构动态变化 |
Nguyen, T. H. |
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N/A |
pH-dependent structural dynamics of the neuropeptide Y in aqueous solution |
| 等离子体膜囊泡和磷脂酰胆碱-胆固醇囊泡的形状揭示了它们的有效自发曲率 |
Kaur, H. |
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N/A |
Shapes of Plasma Membrane Vesicles and PC-Cholesterol Vesicles Reveal Their Effective Spontaneous Curvature |
| RNA梯度可以引导凝聚物向启动子区域移动：这对增强子-启动子接触以及凝聚物-启动子亲吻现象具有重要意义。 |
Goh, D. |
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N/A |
RNA gradients can guide condensates toward promoters: implications for enhancer-promoter contacts and condensate-promoter kissing |
| 支气管镜诱导的转基因肺癌猪模型的人类可转化性特征 |
Joshi, K. |
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N/A |
Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability |
| 阻断SHP2可增强FGFR2抑制剂的作用，并克服FGFR2扩增型胃癌中的耐药性。 |
Zhang, Y. |
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N/A |
Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer |
| 癌症中N基因和T基因的动力学 |
Perez, G. J. G. |
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N/A |
Dynamics of N-genes and T-genes in cancer |
| 通过SdFFF和UHF-DEP标准化方法对结直肠癌细胞的特征化和分离：转录组分析强调 |
JEMFER, C. |
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N/A |
Towards a standardised method for the characterisation and isolation of colorectal cancer stem cells by SdFFF and UHF-DEP: highlighted by transcriptomic analysis |
| 腱生蛋白-C增强甲状腺癌中的Wnt信号传导 |
Hartmann, H. A. |
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N/A |
Tenascin-C potentiates Wnt signaling in thyroid cancer |
| 氯吡硫磷诱导肺转移并调节三阴性乳腺癌模型中的癌症干细胞标志物 |
Lasagna, M. |
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N/A |
Chlorpyrifos induces lung metastases and modulation of cancer stem cell markers in triple negative breast cancer model |
| MPS1抑制剂NTRC 0066-0在体外和体内对胶质母细胞瘤疗效之间的脱节 |
de Gooijer, M. C. |
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N/A |
Disconnect between in vitro and in vivo efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma |
| 血小板特异性P2Y1受体缺陷小鼠对脂多糖的反应中白细胞募集受到抑制。 |
Pan, D. |
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N/A |
Platelet-specific P2Y1 receptor deficient mice have suppressed leukocyte recruitment in response to lipopolysaccharide. |
| Septins通过调节心肌细胞的储存操作钙内流来调控心脏收缩力。 |
Tripoli, B. A. |
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N/A |
Septins regulate heart contractility through modulation of cardiomyocyte store-operated calcium entry |
| 循环小鼠来源的外泌体调节围绝经期小鼠肝脏转录组，与年龄无关 |
Zanini, B. |
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N/A |
EXOSOMES FROM CYCLIC MICE MODULATE LIVER TRANSCRIPTOME IN ESTROUPAUSE MICE INDEPENDENT OF AGE |
| 利用基于集成网络的系统生物学方法预测与水稻（Oryza sativa）种子发育相关的新候选蛋白质，并分析其子模块和蛋白质枢纽。 |
De Silva, M. R. P. |
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N/A |
Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice (Oryza sativa) using an ensemble network-based systems biology approach. |
| 发现和利用主动感知模式以实现基于经验可观测性的估计 |
Cellini, B. |
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N/A |
Discovering and exploiting active sensing motifs forestimation with empirical observability |
| 高效有限差分法估计随机离散生化系统的二阶参数敏感性 |
Jabeen, F. |
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N/A |
Efficient Finite-Difference Estimation of Second-Order Parametric Sensitivities for Stochastic Discrete Biochemical Systems |
| 一项针对心力衰竭的跨研究转录患者图谱揭示了心脏重塑过程中保守的多细胞协调机制。 |
Lanzer, J. D. |
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N/A |
A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling |
| 常见的长足海绵属海绵花园：东北太平洋长足海绵科的分类修订揭示了许多隐秘的引入物种 |
Turner, T. L. |
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N/A |
A common garden of Halichondria sponges: taxonomic revision of Northeast Pacific Halichondriidae reveals many cryptic introduced species |
| 血红素氧合酶-1对干扰素刺激基因表达的影响 |
Chudy, P. |
PDF |
N/A |
Effect of heme oxygenase-1 on the expression of interferon-stimulated genes |
| 使用PANDORA进行MHC II类分子的双向肽构象预测 |
Rademaker, D. T. |
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N/A |
Bidirectional Peptide Conformation Prediction for MHC Class II using PANDORA |
| TRPV4介导的机械转导调控瓣膜间质细胞向肌成纤维细胞的分化：对主动脉瓣狭窄的启示 |
Mukherjee, P. |
PDF |
N/A |
TRPV4-mediated Mechanotransduction Regulates the Differentiation of Valvular Interstitial Cells to Myofibroblasts: Implications for Aortic Stenosis |
| Aramchol 减轻了胆道纤维化小鼠模型中的纤维化，并阻断了 TGFβ 诱导的胆管细胞中的纤维炎症介质。 |
Aseem, S. O. |
PDF |
N/A |
Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes |
| Miro1表达改变全局基因表达、ERK1/2磷酸化、氧化应激以及细胞周期进程 |
Shannon, N. |
PDF |
N/A |
Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression |
| HumanTestisDB：睾丸转录组学和细胞相互作用的综合图谱 |
Wang, M. |
PDF |
N/A |
HumanTestisDB: A Comprehensive Atlas of Testicular Transcriptomics and Cellular Interactions |
| 衰老对小鼠骨折后免疫和骨膜反应的影响 |
King, J. S. |
PDF |
N/A |
Effects of Aging on the Immune and Periosteal Response to Fracture in Mice |
| 抑制DPP4活性通过支持脂肪酸和嘌呤代谢以及减轻炎症来保护由hiPSC衍生的脂肪性肝细胞（HLCs）。 |
Loerch, C. |
PDF |
N/A |
Inhibiting DPP4 activity protects hiPSC-derived steatotic HLCs by supporting fatty acid and purine metabolism and dampening inflammation |
| L-乳酸通过MCT1运输、诱导代谢重编程和基因表达调控，诱导短期和长期的心脏保护作用。 |
Cler, M. |
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N/A |
L-lactic acid induces short- and long-term cardioprotective effects through MCT1 transport, induction of metabolic reprogramming, and gene expression modulation. |
| CXXC5是一种泛素化蛋白，通过泛素化-蛋白酶体途径被降解。 |
Ayten, H. |
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N/A |
CXXC5 is a ubiquitinated protein and is degraded by the ubiquitination-proteasome pathway |
| 新型小麦胚凝集素基质谱流式细胞术细胞条码标记试剂，适用于异质性、活体或固定样本 |
Hannan, R. T. |
PDF |
N/A |
Novel wheat germ agglutinin-based mass cytometry cell barcoding reagent for heterogeneous, live or fixed sample |
| 口服暴露于PET微塑料会改变胰腺转录组——这对1型糖尿病的发病机制具有重要意义 |
Mierzejewski, K. |
PDF |
N/A |
Oral exposure to PET microplastics alters the pancreatic transcriptome-implications for the pathogenesis of type 1 diabetes |
| 不对称基因流动维持着丰富的分布中心 |
Hancock, Z. B. |
PDF |
N/A |
Asymmetric gene flow maintains an abundant range center |
| 子宫接受性的标志早于胎盘哺乳动物出现 |
Basanta, S. |
PDF |
N/A |
Hallmarks of uterine receptivity predate placental mammals |
| 玉米重组景观在驯化过程中发生了演变。 |
Epstein, R. |
PDF |
N/A |
The maize recombination landscape evolved during domestication. |
| 通过比较转录组学深入了解四足动物双锥体的进化起源 |
Tommasini, D. |
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N/A |
Comparative transcriptomic insights into the evolutionary origin of the tetrapod double cone |
| 阿尔法细胞理论：模拟生命系统中的自组装和动态过程 |
Gruhlke, M. C. H. |
PDF |
N/A |
Alpha Cell Theory: Modeling Self-Assembly and Dynamic Processes in Living Systems |
| 氨基酸性质、替代速率以及近中性理论 |
James, J. |
PDF |
N/A |
Amino acid properties, substitution rates, and the nearly neutral theory |
| 范围扩张的历史生物地理学预测了繁殖保障的空间模式 |
Urquhart-Cronish, M. |
PDF |
N/A |
The historical biogeography of range expansion predicts spatial patterns in reproductive assurance |
| 磁性细菌在天然孔隙网络中实现最佳导航 |
Petroff, A. P. |
PDF |
N/A |
Magnetotactic Bacteria Optimally Navigate Natural Pore Networks |
| 细菌生命树中利福平抗性的进化与可进化性 |
Bolourchi, N. |
PDF |
N/A |
Evolution and evolvability of rifampicin resistance across the bacterial tree of life |
| 在免疫检查点阻断的背景下定义CD8+ T细胞受体库的遗传决定因素 |
Ng, E. |
PDF |
N/A |
Defining the genetic determinants of CD8+ T cell receptor repertoire in the context of immune checkpoint blockade |
| 以单个氨基酸分辨率进行蛋白质测序可以识别出区分肌动蛋白原形态的肽段。 |
Sittipongpittaya, N. |
PDF |
N/A |
Protein sequencing with single amino acid resolution discerns peptides that discriminate tropomyosin proteoforms |
| 长寿中的玛土撒拉蛋白：通过数学基因组学揭示其影响 |
Hassan, S. S. |
PDF |
N/A |
Methuselah Proteins in Longevity: Unraveling Their Impact Through Mathematical Genomics |
| 去氨酶辅助的单分子和单细胞染色质纤维测序 |
Swanson, E. G. |
PDF |
N/A |
Deaminase-assisted single-molecule and single-cell chromatin fiber sequencing |
| 新生转录本O-MAP揭示了由RBM20和TTN RNA构建的单基因位点亚核区室的分子结构 |
Kania, E. E. |
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Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA |