| 泛素介导的人类26S蛋白酶体在底物降解过程中的自调节隐藏动力学 |
Wu, Z. |
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Hidden dynamics of ubiquitin-mediated autoregulation of human 26S proteasome during substrate degradation |
| 多重连接组轨迹使得多种连接模式能够并行实现。 |
Mostame, P. |
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A multiplex of connectome trajectories enables several connectivity patterns in parallel |
| 增强突变热点预测：原子波动的作用 |
Martis, E. A. F. |
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Enhancing Mutational Hotspot Predictions: The Role of Atomic Fluctuations |
| 肌动蛋白失调引发神经内分泌可塑性和免疫逃逸：小细胞肺癌的一个脆弱性 |
Seo, Y. |
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Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer |
| 增强轴向光学镊子的应用力和作用范围 |
Milstein, J. N. |
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Enhancing the Applied Force and Range of Axial Optical Tweezers |
| 撤销：钢琴演奏中认知与情感相互影响的神经生理学 |
Higuchi, M. K. K. |
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WITHDRAWN: Neurophysiology of Reciprocal Influence of Cognition and Emotion in Pianistic Performances |
| 阿尔茨海默病中性别依赖性脆弱性的原因：后扣带皮层中受损的Parvalbumin中间神经元 |
Terstege, D. J. |
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Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer's disease |
| NOTCH1的表达状态转变伴随着人类早期视网膜祖细胞中的染色质重塑 |
Watabe, Y. |
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Expression status transition of NOTCH1 accompanies chromatin remodeling in human early retinal progenitor cells |
| 探究数学学习困难儿童的前顶叶网络及激活情况：不同缺陷特征的案例研究 |
Wang, F. |
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Investigating Frontoparietal Networks and Activation in Children with Mathematics Learning Difficulties: Cases with Different Deficit Profiles |
| scEGOT：基于熵高斯混合最优传输的单细胞轨迹推断框架 |
Yachimura, T. |
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scEGOT: Single-cell trajectory inference framework based on entropic Gaussian mixture optimal transport |
| 物种特性和群落结构可以推动生态系统中大规模的空间效应传播。 |
Garcia-Callejas, D. |
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Species traits and community structure can drive large-scale spatial propagation of effects in ecosystems |
| 基于模型的突触可塑性规则推断 |
Mehta, Y. |
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Model Based Inference of Synaptic Plasticity Rules |
| 室管膜下区神经胶质生成调节脑缺血后胶质瘢痕处的细胞外基质 |
Ardaya, M. |
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Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia |
| 靶向缺氧人乳腺癌干细胞的分子货物胞内递送 |
Makela, A. V. |
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Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells |
| 将残基级蛋白质语言模型嵌入与最优传输相结合 |
NaderiAlizadeh, N. |
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N/A |
Aggregating Residue-Level Protein Language Model Embeddings with Optimal Transport |
| 驯化的转座子蛋白L1TD1与其祖先L1 ORF1p相互作用，促进LINE-1逆转录转座 |
Kavaklioglu, G. |
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The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition |
| 基于相关自然统计的高效编码解释的重量错觉 |
Bays, P. |
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Weight illusions explained by efficient coding based on correlated natural statistics |
| 受损的26S蛋白酶体导致小鼠学习和记忆缺陷，并诱导由NF-κB介导的神经炎症 |
Huber, C. |
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Impaired 26S proteasome causes learning and memory deficiency and induces neuroinflammation mediated by NF-κB in mice |
| 棕色藻类作为沿海生态系统关键组成部分的进化基因组学研究 |
Denoeud, F. |
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Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems |
| 机械负荷揭示了在小鼠心脏代谢疾病中，心肌细胞固有的刚度对舒张功能障碍的贡献。 |
Janssens, J. V. |
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Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease |
| 皮质丘脑模型在睡眠神经生理学中的应用及其在移动脑电图中的应用 |
Morshedzadeh, T. |
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Corticothalamic modelling of sleep neurophysiology with applications to mobile EEG |
| 单细胞RNA测序揭示了不同关系间的转录同步性 |
Brusman, L. E. |
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Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships |
| 一种涉及巨型可移动元件的古老倒位多态性在入侵性真菌病原体中 |
Hartmann, F. E. |
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An old inversion polymorphism involving giant mobile elements in an invasive fungal pathogen |
| 在喜马拉雅山西部，尺蛾科蛾类群落的特征分布并不随海拔梯度变化。 |
Dey, P. |
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Trait distribution in Geometrid moth assemblages does not vary along a western Himalayan elevational gradient |
| 一种涉及多个P450基因的基因组重复有助于登革热蚊子埃及伊蚊的杀虫剂抗性。 |
Bacot, T. |
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A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti |
| 单细胞RNA测序（scRNA-seq）和单细胞ATAC测序（scATAC-seq）揭示了支持细胞通过阶段特异性通信在非阻塞性无精症中调节精子发生障碍 |
Wang, S. |
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ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia |
| 在生物物理上真实的兴奋-抑制尖峰网络中进行高效编码 |
Koren, V. |
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Efficient coding in biophysically realistic excitatory-inhibitory spiking networks |
| 多价Afadin相互作用促进IDR介导的凝聚体形成和上皮细胞的连接分离 |
Kuno, S. |
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Multivalent Afadin Interaction Promotes IDR-Mediated Condensate Formation and Junctional Separation of Epithelial Cells |
| 脑膜调节性T细胞衍生的脑啡肽调控痛觉 |
Midavaine, E. |
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Meningeal Regulatory T cell-derived enkephalin gates nociception |
| 非巢友歧视在蚂蚁中起到排除社会性寄生同种个体的作用 |
Nakamura, T. P. |
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Discrimination against non-nestmates functions to exclude socially parasitic conspecifics in an ant |
| 白细胞介素-1通过诱导肌动蛋白束的形成，阻止了SARS-CoV-2诱导的膜融合，从而限制了病毒的传播。 |
Zheng, X. |
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Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles |
| fmo-4通过ER到线粒体的钙调节在秀丽隐杆线虫中促进长寿和应激抗性 |
Tuckowski, A. M. |
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fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans |
| 热带珊瑚礁鱼类的比较宏基因组学研究表明，尽管宿主和饮食各异，但其肠道核心功能高度保守，同时存在与饮食相关的功能基因富集现象。 |
Wu, D. G. |
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Comparative metagenomics of tropical reef fishes show conserved core gut functions across hosts and diets with diet-related functional gene enrichments |
| 毒力进化：跳出宿主的思维框架 |
Silva, L. M. |
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Virulence evolution: thinking outside of the host |
| 胰腺癌细胞通过隧道纳米管交换核糖体 |
Martinkova, S. |
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Pancreatic cancer cells exchange ribosomes through tunneling nanotubes |
| 在裂顎目（sclerosomatid Opiliones）中，婚配礼物的减少与行为性冲突的增加相吻合。 |
Brown, T. A. |
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The reduction of nuptial gifts in sclerosomatid Opiliones coincides with increased behavioural sexual conflict |
| 细胞信号：多模态与情境化机器学习基础在治疗学中的应用 |
Velez-Arce, A. |
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Signals in the Cells: Multimodal and Contextualized Machine Learning Foundations for Therapeutics |
| 系统建模揭示了ME/CFS和长期新冠肺炎中共同的代谢失调及新型治疗方法 |
Li, G.-H. |
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Systems Modeling Reveals Shared Metabolic Dysregulation and Novel Therapeutic Treatments in ME/CFS and Long COVID |
| 脂肪体衍生细胞因子Upd2调控果蝇气管干细胞的有序迁移 |
Dong, P. |
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Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila |
| 更快速的基于模型的祖先比例估计 |
Santander, C. |
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Faster model-based estimation of ancestry proportions |
| 可移动元件积累推动南美洲刺蛾物种Hylesia metabus（鳞翅目：天蚕蛾科）基因组大小增加 |
Perrier, C. |
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Transposable element accumulation drives genome size increase in Hylesia metabus (Lepidoptera: Saturniidae), an urticating moth species from South America |
| 人类大脑祖先条形码 |
Shibata, D. |
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N/A |
Human Brain Ancestral Barcodes |
| 鉴定用于神经退行性疾病治疗的新型小分子伴侣激活剂 |
Ho, A. |
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Identification of novel small molecule chaperone activators for neurodegenerative disease treatment |
| 经济高效的DNA存储技术：DNA活字印刷术 |
Wang, C. |
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Cost-effective DNA storage with DNA movable type |
| PINK1的缺失会导致黑质纹状体多巴胺能神经元中依赖年龄的线粒体运输缺陷，这是由于p38 MAPK的异常激活所致。 |
Zhao, J. |
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Loss of PINK1 causes age-dependent mitochondrial trafficking deficits in nigrostriatal dopaminergic neurons through aberrant activation of p38 MAPK |
| 照亮微生物席的组装：蓝细菌和绿屈挠菌门合作构建光响应生物膜 |
Bunbury, F. |
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Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms |
| 外毛细胞搅动耳蜗内的液体。 |
Lee, C. |
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N/A |
Outer hair cells stir cochlear fluids |
| Nup107是果蝇（Drosophila melanogaster）中Torso介导的变态转变的关键调控因子。 |
Kawadkar, J. |
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Nup107 is a crucial regulator of Torso-mediated metamorphic transition in Drosophila melanogaster |
| 在斑马鱼胚胎的自发神经活动中，出生顺序指定了运动回路的招募 |
Abi Younes, M. |
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Birth order specified recruitment of motor circuits during spontaneous neural activity in zebrafish embryo |
| NEBULA101：一个用于研究语言能力在行为、大脑结构和功能方面的开放数据集 |
Rampinini, A. C. |
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NEBULA101: an open dataset for the study of language aptitude in behaviour, brain structure and function |
| Inpp5e 对光感受器外节维护至关重要 |
Gupta, M. |
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Inpp5e Is Critical for Photoreceptor Outer Segment Maintenance |
| 基于秀丽隐杆线虫毒性测试的自动化微流控平台 |
Wu, J. |
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N/A |
An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans |
| 结构导向的瘿形成微生物分泌组分析提供了对效应子多样性和进化的见解 |
Mukhopadhyay, S. |
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N/A |
Structure-guided secretome analysis of gall-forming microbes offers insights into effector diversity and evolution |
| 负电荷，而非必需的磷酸化，是14-3-3蛋白配体识别所必需的 |
Kamayirese, S. |
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Negative Charges, Not Necessary Phosphorylation, are Required for Ligand Recognition by 14-3-3 Proteins |
| 尼安德特人衍生的变异影响人类疾病位点的颅面增强子活性 |
Uttley, K. |
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Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus |
| 在右美托咪定诱导意识丧失期间大脑连接性和神经血管动力学的变化 |
Fotiadis, P. |
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N/A |
Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness |
| 在观察动作时，空间信息和解剖信息的处理具有不同的时序 |
Waltzing, B. M. |
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N/A |
Separate timescales for spatial and anatomical information processing during action observation |
| 成年大鼠的多重情境辨别：性别差异与厌恶记忆的时间依赖性泛化动态 |
Alves, F. N. L. |
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N/A |
Multiple context discrimination in adult rats: sex variability and dynamics of time-dependent generalization of an aversive memory |
| APOE基因型和生物年龄影响与生物能量代谢相关的多组学关联 |
Ellis, D. S. |
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N/A |
APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics |
| 中间普雷沃菌的蛋白酶interpain A促进人舌鳞状细胞癌细胞增殖和迁移 |
Chang, S.-M. |
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The protease interpain A of Prevotella intermedia promotes human OSCC cells proliferation and migration |
| 早衰症中层粘连蛋白的相行为与解离动力学：聚合物模型研究 |
Hameed, H. A. |
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N/A |
Phase Behavior and Dissociation Kinetics of Lamins in a Polymer Model of Progeria |
| Metagenomics-Toolkit：灵活高效的基于云的宏基因组学工作流程，具备机器学习驱动的资源分配功能 |
Belmann, P. |
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N/A |
Metagenomics-Toolkit: The Flexible and Efficient Cloud-Based Metagenomics Workflow featuring Machine Learning-Enabled Resource Allocation |
| Gb3三糖基化外泌体作为志贺毒素1型的新型中和剂 |
Mikolajczyk, K. |
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N/A |
Gb3 trisaccharide-bearing exosomes as a novel neutralizer for Shiga toxin type 1 |
| CD90识别出具有不同激活和静息维持模式的肌肉干细胞的不同亚群 |
Kheir, E. |
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CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance |
| 全面的蛋白质组学特征描述了高尔基体内运输中间体 |
Sumya, F. T. |
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N/A |
Comprehensive Proteomic Characterization of Intra-Golgi Trafficking Intermediates |
| 系统性炎症和淋巴细胞激活先于类风湿性关节炎 |
He, Z. |
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N/A |
Systemic inflammation and lymphocyte activation precede rheumatoid arthritis |
| 利用改良的群体分离分析法鉴定出芽殖酵母铜抗性中的上位性和隐性数量性状位点 |
Buzby, C. |
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N/A |
Epistasis and cryptic QTL identified using modified bulk segregant analysis of copper resistance in budding yeast |
| 时空转录组分析揭示了发育过程中分子梯度模式以及沿耳蜗轴的音调组织结构。 |
Yan, M. |
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N/A |
Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along cochlear axis |
| 最佳竞争者：互利共生者（如传粉者）的吸引力与选择之间的平衡推动了促进作用，并可能促进作物传粉。 |
Dornhaus, A. |
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N/A |
Optimal competitors: the balance of attraction and choices of mutualists, like pollinators, drives facilitation and may promote crop pollination |
| RBFOX1缺陷的纠正能够修复亨廷顿病的错误剪接并减轻病理 |
Lozano-Munoz, D. |
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N/A |
Correction of RBFOX1 deficit rescues Huntington's disease mis-splicing and pathology |
| 丛枝菌根真菌基因型和核组织作为宿主植物营养获取和稳定碳捕获的驱动因素 |
Ferguson, R. |
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Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon capture |
| 加拿大科学研究生的津贴低于贫困线。 |
Fraass, A. J. |
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N/A |
Canadian science graduate stipends lie below the poverty line |
| 使用荧光图像中的不均匀背景减除法进行即时早期基因表达神经元的自动细胞检测 |
Osanai, H. |
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N/A |
Automated cell detection for immediate early gene-expressing neurons using inhomogeneous background subtraction in fluorescent images |
| 南非2024年猴痘分子流行病学初步报告 |
Featherston, J. |
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N/A |
Preliminary report on the molecular epidemiology of mpox, South Africa 2024 |
| scLong：一种拥有十亿参数的基础模型，用于在单细胞转录组学中捕捉长程基因上下文 |
Bai, D. |
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N/A |
scLong: A Billion-Parameter Foundation Model for Capturing Long-Range Gene Context in Single-Cell Transcriptomics |
| 以少求多：基于模拟的推断使扩散加权磁共振成像在极短的采集时间内实现高精度 |
Eggl, M. F. |
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N/A |
More with less: Simulation-based inference enables accurate diffusion-weighted MRI with minimal acquisition time |
| 持续的感觉运动转换增强了猕猴运动皮层神经动力学对扰动的鲁棒性 |
Zheng, C. |
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N/A |
Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex |
| 扩展杏仁核促肾上腺皮质激素释放激素神经元调控草原田鼠（Microtus ochrogaster）在社会挫败后形成的配对结合中的性别二态性变化 |
Tickerhoof, M. C. |
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N/A |
Extended amygdala corticotropin-releasing hormone neurons regulate sexually dimorphic changes in pair bond formation following social defeat in prairie voles (Microtus ochrogaster) |
| CircAge：一个综合性的跨物种和组织的老化相关环状RNA资源 |
Dong, X. |
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N/A |
CircAge: A Comprehensive Resource for Aging-Associated Circular RNAs Across Species and Tissues |
| 整合知识、组学和人工智能，开发患者特异性的虚拟化身 |
Bekkar, A. |
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N/A |
Integrating knowledge, omics and AI to develop patient-specific virtual avatars |
| 基于图自编码器和StrNN的心力衰竭患者死亡率因果分析 |
Kim, D. |
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N/A |
Graph Autoencoder and StrNN based Causal Analysis of Mortality in Heart Failure Patients |
| 抑制富含丝氨酸和精氨酸的剪接因子3可诱导表皮分化并降低皮肤鳞状细胞癌风险 |
Donohue, I. M. |
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N/A |
Inhibition of serine and arginine-rich splicing factor 3 induces epidermal differentiation and decreases cutaneous squamous cell carcinoma risk |
| TRPV4钙通透性通道有助于主动脉狭窄中的瓣膜硬化 |
Dutta, B. |
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N/A |
TRPV4 calcium-permeable channel contributes to valve stiffening in aortic stenosis |
| 对大脑中非言语听觉记忆的系统性及元分析回顾 |
Campo, F. F. |
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N/A |
A systematic and meta-analytic review of non-verbal auditory memory in the brain |
| 偏头痛与内感受之间的关系：准确性正常但感觉和行为改变 |
Jones, S. |
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N/A |
Relationships between migraine and interoception: normal accuracy but altered sensibility and behaviour |
| 多结果生存数据的惩罚降秩回归支持年龄相关疾病的共同代谢风险评分 |
Sluiskes, M. H. |
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N/A |
Penalized reduced rank regression for multi-outcome survival data supports a common metabolic risk score for age-related diseases |
| 用于跨物种测试膜定位标签的工具包 |
Karapidaki, I. |
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N/A |
A toolkit for testing membrane localisation tags across species |
| 耦合人地系统建模趋势：范围综述 |
Thampi, V. |
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N/A |
Trends in Coupled Human-Environment Systems Modelling: A Scoping Review |
| 传统草药提取物对抗多药耐药细菌的有效性：综述 |
Pane, Y. S. |
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N/A |
Effectiveness of Traditional Herbal Extracts Against Multidrug-Resistant Bacteria: A Review |
| 海马体OLM中间神经元调节CA1位置细胞的可塑性和重映射 |
Udakis, M. |
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N/A |
Hippocampal OLM interneurons regulate CA1 place cell plasticity and remapping |
| γ-分泌酶功能障碍谱作为PSEN1、PSEN2和APP致病基因中ADAD发病年龄的统一预测因子 |
Gutierrez Fernandez, S. |
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N/A |
Spectrum of gamma-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes |
| 气候变化塑造了亚高山草地实验中的物种丰富度-均匀度关系 |
Muehlbauer, L. K. |
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N/A |
Climate change shapes richness-evenness relationships in a subalpine grassland experiment |
| 个体间基因表达的变异性意味着大脑偏倚基因在各器官中具有稳定的调控机制。 |
Bucao, C. F. |
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N/A |
Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs |
| 系统性基因组-表观基因组分析揭示了胃肠道腺癌中与MYB相关的超级增强子的谱系特异性及功能意义 |
Li, F. |
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N/A |
Systemic genome-epigenome analysis captures the lineage specificity and functional significance for MYB associated super-enhancer in gastrointestinal adenocarcinoma |
| GHT-SELEX 展示了许多人源转录因子出乎意料的高内在序列特异性及复杂的 DNA 结合特性。 |
Jolma, A. |
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N/A |
GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors |
| 大量未知的人类转录因子与基因组暗物质结合 |
Razavi, R. |
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N/A |
Extensive binding of uncharacterized human transcription factors to genomic dark matter |
| 一种综合方法用于优先筛选牛复杂性状的候选因果基因 |
Ghoreishifar, M. |
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N/A |
An integrative approach to prioritize candidate causal genes for complex traits in cattle |
| gen3DNet：一个用于生成三维网络模型的R包 |
Mollah, S. |
PDF |
N/A |
gen3DNet: An R Package for Generating 3D Network Models |
| scExplorer：一个全面的单细胞RNA测序数据分析网络服务器 |
Galaz, S. F. H. |
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N/A |
scExplorer: A Comprehensive Web Server for Single-Cell RNA Sequencing Data Analysis |
| 虚拟实验室：AI智能体设计新型SARS-CoV-2纳米抗体并经实验验证 |
Swanson, K. |
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N/A |
The Virtual Lab: AI Agents Design New SARS-CoV-2 Nanobodies with Experimental Validation |
| 一种计算上非结构化蛋白质的简单方法：一些发现 |
Powell, A. |
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N/A |
A simple method for computationally unstructuring proteins: some findings |
| 单细胞多组学分析揭示了NPM1突变型AML克隆演化中的基因型-免疫表型关系 |
Drucker, M. |
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N/A |
Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis |
| 通过呼出气颗粒（PExA）收集的远端肺液态活检中的microRNA和非靶向蛋白质组分析揭示了细胞外囊泡的存在。 |
Bonatti, M. |
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N/A |
microRNA and non-targeted proteome analysis of liquid biopsies from the distal lung collected by Particles in Exhaled Air (PExA) reveals presence from extracellular vesicles |
| 工程化和进化型自养大肠杆菌菌株的系统级表征 |
Yilmaz, S. |
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N/A |
System-level characterization of engineered and evolved formatotrophic E. coli strains |
| 调控蛋白质在十种人类癌症类型中丰度的主调控因子 |
Wang, Z. |
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N/A |
Master regulators governing protein abundance across ten human cancer types |
| DIA-BERT：用于增强DIA蛋白质组学数据分析的端到端预训练变换器模型 |
Liu, Z. |
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N/A |
DIA-BERT: pre-trained end-to-end transformer models for enhanced DIA proteomics data analysis |
| 初级视觉皮层中运动的潜在编码 |
Cosnier-Horeau, C. |
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N/A |
Latent encoding of movement in primary visual cortex |
| SIMPL：从行为中优化神经表征的扩展且简便的方法 |
George, T. M. |
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N/A |
SIMPL: Scalable and hassle-free optimization of neural representations from behaviour |
| 尼莫地平在体外可减少小胶质细胞的激活，这一结论通过形态学表型、吞噬活性和新一代RNA测序得以证实。 |
Pesti, I. |
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N/A |
Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and next generation RNA sequencing |
| 高级视觉皮层的组织与视觉信息而非抽象的语言信息相一致。 |
Shoham, A. |
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N/A |
The organization of high-level visual cortex is aligned with visual rather than abstract linguistic information |
| ConvexGating 从单细胞流式细胞数据中的聚类推断出门控策略。 |
Friedrich, V. D. |
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N/A |
ConvexGating infers gating strategies from clusters in single cell cytometry data |
| 单核苷酸开关赋予假单胞菌噬菌体抗性 |
Vacheron, J. |
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N/A |
Single nucleotide switches confer bacteriophage resistance to Pseudomonas protegens |
| 疫苗诱导和混合免疫对澳大利亚昆士兰州两个队列中关注的SARS-CoV-2变种的保护作用（2021-2022年）。 |
Parry, R. H. |
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N/A |
Vaccine-induced and hybrid immunity against SARS-CoV-2 variants of concern in two cohorts in Queensland, Australia (2021-2022). |
| 秀丽隐杆线虫（C. elegans）中的体细胞性腺形态发生需要通过HBL-1作用的异时性通路。 |
Minutillo, M. |
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N/A |
Somatic gonad morphogenesis in C. elegans requires the heterochronic pathway acting through HBL-1 |
| 母体运动以一种与运动方式特异性的方式改变胎盘蛋白质组 |
Jevtovic, F. |
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N/A |
Maternal exercise alters placental proteome in an exercise mode-specific manner |
| 通过BaFOMS视角解读生态流行病学系统中的记忆模式：一种贝叶斯分数阶模型选择方法 |
Mestry, D. V. |
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N/A |
Deciphering Memory Patterns in Eco-Epidemiological systems through the lens of BaFOMS: A Bayesian Fractional Order Model Selection Method |
| 单配制果蝇会重新交配：热暴露对交配行为和繁殖力的可塑性和进化影响——以暗色果蝇为例 |
Grandela, A. |
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N/A |
Monandrous flies do remate: plastic and evolutionary consequences of heat exposure on mating behaviour and fertility in Drosophila subobscura |
| 对在COVID-19第一波期间导致医院爆发的持久性、耐唑类药物的C. parapsilosis菌株的基因组特征分析 |
Vumbaca, M. |
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N/A |
Genomic characterization of a persistent, azole-resistant C. parapsilosis strain responsible for a hospital outbreak during the first COVID-19 wave |
| 跨平台DNA基序发现与基准测试：探索研究不足的人类转录因子结合特异性 |
Vorontsov, I. E. |
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N/A |
Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors |
| QT-WEAVER：尽管基因树估计存在误差，校正四重分布仍能改善系统基因组学分析 |
Hasan, N. B. |
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N/A |
QT-WEAVER: Correcting quartet distribution improves phylogenomic analyses despite gene tree estimation error |
| GRIP：用于液相色谱梯度保留时间预测的物理信息神经网络 |
George, K. |
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N/A |
GRIP: physics-informed neural network for gradient retention time prediction in liquid chromatography |
| 在女性中，CETP表达在冷暴露和体温中性环境下均能提高身体代谢率，从而有助于形成更为瘦削的表型。 |
Castelli, J. Z. |
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N/A |
CETP expression in females increases body metabolism under both cold exposure and thermoneutrality contributing to a leaner phenotype |
| 使用分布式仿真在神经网络中建模神经元-星形胶质细胞相互作用 |
Jiang, H.-J. |
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N/A |
Modeling neuron-astrocyte interactions in neural networks using distributed simulation |
| 边缘海的连通性与种群结构——综述 |
Henriksson, S. |
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N/A |
Connectivity and population structure in a marginal sea - a review |
| 在植物协同非自体识别自交不亲和系统中协调冲突的选择压力 |
Jangid, A. |
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N/A |
Reconciling conflicting selection pressures in the plant collaborative non-self recognition self-incompatibility system |
| 解析肺癌恶性肿瘤中复杂基因组重排的进化历程 |
Hu, X. |
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N/A |
Deconstructing evolutionary histories of complex genomic rearrangements in lung malignancies |
| 通过上皮微生理分析平台构建的人类干细胞衍生的肾集合管模型：Epi-MAP |
Hong, S. |
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N/A |
Human Stem Cell-derived Kidney Collecting Duct Model via Epithelial Microphysiological Analysis Platform: Epi-MAP |
| 血-肿瘤屏障类器官重现了胶质母细胞瘤微环境，并实现了治疗递送的高通量建模。 |
Cho, C.-F. |
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N/A |
Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery |
| 血-肿瘤屏障类器官再现了胶质母细胞瘤微环境，并实现了治疗递送的高通量建模。 |
Zhuang, P. |
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N/A |
Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery |
| 微生物群应激诱导miRNA的鉴定，与慢性鼻窦炎（CRS）的网络关系及表达 |
Wei, B. |
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N/A |
Identification of Stress-induced miRNA of Microbial flora, networking, expression with chronic rhinosinusitis (CRS) |
| 通过基因过表达和编辑，以果实表皮特异性nsLTP启动子为目标，针对番茄果实角质层进行研究 |
Alonso, M. |
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N/A |
Targeting the tomato fruit cuticle by gene overexpression and editing with the fruit epidermis-preferential nsLTP promoter |
| 人类单个神经元的活动受到基底外侧杏仁核内源性θ脉冲刺激的调控 |
Campbell, J. M. |
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N/A |
Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala |
| 通过内在运动节奏的频率失谐实现皮层手部和言语区域的功能分离。 |
Anastasopoulou, I. |
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N/A |
Functional segregation of cortical hand and speech areas by frequency detuning of an intrinsic motor rhythm. |
| 饮食诱导的肥胖与慢性压力在小鼠更年期模型中的相互作用 |
Knox, N. |
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N/A |
The Interaction Of Diet-Induced Obesity And Chronic Stress In A Mouse Model Of Menopause |
| 经训练的先天免疫系统减弱了巨噬细胞对癌细胞的吞噬作用 |
Chatzis, A. |
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N/A |
Trained innate immunity attenuates macrophage efferocytosis of cancer cells |
| PGE2-cAMP和IFN-γ信号通路对TNF反应和IL-1b+巨噬细胞的调控作用 |
Sokhi, U. K. |
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N/A |
Opposing Regulation of TNF Responses and IL-1b+ Macrophages by PGE2-cAMP and IFN-g Signaling |
| 基于质谱的抗体测序系统性基准测试揭示了方法学偏差 |
Chernigovskaya, M. |
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N/A |
Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases |
| 转录因子GABPA是原始多能性的主调控因子 |
Zhou, C. |
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N/A |
The transcription factor GABPA is a master regulator of naive pluripotency |
| 在原代人类软骨细胞中拼接响应的QTLs，识别出潜在的骨关节炎风险基因 |
Byun, S. |
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N/A |
Response splicing QTLs in primary human chondrocytes identifies putative osteoarthritis risk genes |
| LOL-EVE：基于进化序列预测启动子变体效应 |
Shearer, C. |
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N/A |
LOL-EVE: Predicting Promoter VariantEffects from Evolutionary Sequences |
| 通过囊泡出口实现的非破坏性转录组学 |
Armbrust, N. |
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N/A |
Non-destructive transcriptomics via vesicular export |
| 泛癌研究：从原发肿瘤到转移瘤的信号系统转变 |
Zhou, W. |
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N/A |
Pan-cancer study on transition of signaling systems from primary to metastatic tumors |
| 电荷调节和离子核内环境对核小体核心颗粒的影响 |
Nap, R. J. |
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N/A |
The Impact of Charge Regulation and Ionic Intranuclear Environment on the Nucleosome Core Particle |
| 空间转录组学揭示了急性髓系白血病在髓外和髓内组织中的炎症和转分化状态 |
Dasdemir, E. |
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N/A |
Spatial Transcriptomics Reveals Inflammation and Trans-differentiation States of Acute Myeloid Leukemia in Extramedullary and Medullary Tissues |
| 星形胶质细胞-神经元共培养的3D肿瘤球体模型用于抗癌药物筛选 |
Murugappan, S. |
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N/A |
Astrocyte-Neuron co-cultured 3D tumor spheroid model for Anti-cancer Drug Screening |
| 单手和双手运动学习过程中微分贝塔和伽马活动的调制 |
Wu, M. |
PDF |
N/A |
Differential beta and gamma activity modulation during unimanual and bimanual motor learning |
| C3aR1 在 β 细胞上的作用增强了 β 细胞的功能和生存能力。 |
Lima, R. |
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N/A |
C3aR1 on β cells enhances β cell function and survival |
| Spotiphy使得在整个切片上实现单细胞空间全转录组学成为可能 |
Yang, J. |
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N/A |
Spotiphy enables single-cell spatial whole transcriptomics across the entire section |
| 黑素浓缩激素投射到伏隔核会增强食物消费的奖赏价值，但不会引发进食或快速眼动睡眠。 |
Furman, K. L. |
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N/A |
Melanin concentrating hormone projections to the nucleus accumbens enhance the reward value of food consumption and do not induce feeding or REM sleep |
| 前额叶皮层编码与运动解耦的行为状态 |
Rautio, I. V. |
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N/A |
Prefrontal cortex encodes behavior states decoupled from movement |
| 结核分枝杆菌在碳饥饿条件下的蛋白质组学特征分析 |
Devlin, K. L. |
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N/A |
Proteomic characterization of Mycobacterium tuberculosis subjected to carbon starvation |
| 生物边界条件调控肺泡细胞对烟曲霉孢子的内化作用 |
Schiefermeier-Mach, N. |
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N/A |
Biological Boundary Conditions Regulate the Internalization of Aspergillus Fumigatus Conidia by Alveolar Cells |
| Sigma因子作为潜在靶点以提高重组蛋白表达 |
Pohlen, L. |
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N/A |
Sigma factors as potential targets to enhance recombinant protein expression |
| 西班牙小型陆生哺乳动物粪便样本中DNA病毒的完整基因组 |
Buigues, J. |
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N/A |
Complete genomes of DNA viruses in faecal samples from small terrestrial mammals in Spain |
| 资源环境塑造了人类阴道微生物群的组成和稳定性。 |
Kamiya, T. |
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N/A |
Resource landscape shapes the composition and stability of the human vaginal microbiota |
| 口服衣原体疫苗对宿主肠道微生物群和代谢物组成的影响 |
Huang, Y. |
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N/A |
Impact of oral Chlamydia Vaccination on Host Gut Microbiome and Metabolites Composition |
| 一种用于多种致病真菌的体内烧伤伤口感染模型。 |
Mercado-Soto, N. |
PDF |
N/A |
A conserved in vivo burn wound infection model for diverse pathogenic fungi. |
| 盐度影响了现代潮间带微生物岩的微生物碳酸盐沉淀机制 |
Hsieh, Y. E. |
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N/A |
Salinity impacted microbial carbonate precipitation mechanisms of modern microbialites in peritidal zone |
| 鉴定出一种新的菜豆金色花叶病毒β卫星DNA，并发现与阿萨姆邦Bhut Jolokia辣椒卷叶病相关的病毒复合体 |
Saikia, R. |
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N/A |
Identification of a novel begomovirus betasatellite and occurrence of a viral complex associated with leaf curl disease in Bhut Jolokia in Assam |
| 通过直接检测RNA氧化来定量亚细胞RNA定位 |
Lo, H.-Y. G. |
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N/A |
Quantification of subcellular RNA localization through direct detection of RNA oxidation |
| 通过多重邻近标记技术进行染色质结构图谱绘制 |
Delamarre, A. |
PDF |
N/A |
Chromatin architecture mapping by multiplex proximity tagging |
| 关于代码本的观点：未表征人类转录因子的序列特异性 |
Jolma, A. |
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N/A |
Perspectives on Codebook: sequence specificity of uncharacterized human transcription factors |
| 使用meSMiLE-seq技术鉴定甲基化敏感的人类转录因子 |
Gralak, A. J. |
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N/A |
Identification of methylation-sensitive human transcription factors using meSMiLE-seq |
| 纤维碎片化在种子种群中产生了多样性 |
Pedrola, J. A. |
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N/A |
Fibril fragmentation generates diversity in seed population |
| 蛋白质病原性在单聚集体水平上的分子决定因素 |
Urbanek, A. |
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N/A |
Molecular determinants of protein pathogenicity at the single-aggregate level |
| 脊椎动物R2逆转录转座子复合体在目标引导逆转录过程中的结构及第二链切割后的结构 |
Thawani, A. |
PDF |
N/A |
Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking |
| 压力改变细菌生物分子凝聚物材料状态，并将其功能从mRNA降解转变为储存 |
Ortiz-Rodrlguez, L. A. |
PDF |
N/A |
Stress Changes the Bacterial Biomolecular Condensate Material State and Shifts Function from mRNA Decay to Storage |
| 使用光学光热红外光谱技术检测未染色组织中的未标记微塑料和纳米塑料 |
Duswald, K. |
PDF |
N/A |
Detection of Unlabeled Micro- and Nanoplastics in Unstained Tissue with Optical Photothermal Infrared Spectroscopy |
| 针对非同源末端连接与辐射在极高风险SHH型髓母细胞瘤中的合成致死性 |
DeCarlo, A. |
PDF |
N/A |
Targeting synthetic lethality between non-homologous end joining and radiation in very high-risk SHH medulloblastoma |
| 开发评估YAP-TEAD抑制剂潜力的流程 - 直接抑制TEAD可抑制NF2突变型间皮瘤模型中的癌细胞生长 |
Cunningham, R. |
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N/A |
Development of a pipeline to evaluate YAP-TEAD inhibitor potential - direct TEAD inhibition represses cancerous growth in a NF2-mutant model of mesothelioma |
| 突变型RIT1与YAP合作，推动类似上皮间质转化的肺癌状态 |
Rominger, M. C. |
PDF |
N/A |
Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state |
| TLL1敲低通过增强抗肿瘤免疫抑制前列腺癌进展 |
hao, j. |
PDF |
N/A |
TLL1 knockdown attenuates prostate cancer progression by enhancing antitumor immunity |
| TCR-TRANSLATE：生成真实抗原特异性T细胞受体序列的条件生成 |
Karthikeyan, D. |
PDF |
N/A |
TCR-TRANSLATE: Conditional Generation of Real Antigen Specific T-cell Receptor Sequences |
| 甲型流感病毒转录生成加帽的cRNA，这些cRNA能够激活RIG-I。 |
Elshina, E. |
PDF |
N/A |
Influenza A virus transcription generates capped cRNAs that activate RIG-I |
| 代谢见解：芽孢杆菌科微生物诱导方解石形成的机制及其在生物基建筑材料中的应用 |
Michael, S. |
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N/A |
Metabolic insights into microbially induced calcite formation by Bacillaceae for application in bio-based construction materials |
| 使用新开发的微卫星分型检测方法研究阿萨希毛孢子菌分离株的遗传关系 |
Francisco, E. C. |
PDF |
N/A |
Investigating the genetic relationship of Trichosporon asahii isolates using a newly developed microsatellite typing assay |
| 解析糖尿病足溃疡的分子足迹：计算机辅助发现关键蛋白质和微RNA特征 |
Chudasama, J. M. |
PDF |
N/A |
Unravelling the Molecular Footprints of Diabetic Foot Ulcers: In Silico Discovery of Key Protein and MicroRNA Signatures |
| 用于植物基因组大小估计的流式细胞术标准的重新校准 |
Soni, A. |
PDF |
N/A |
Re-calibration of flow cytometry standards for plant genome size estimation |
| 通过针对与冠状动脉疾病相关的基因，绘制平滑肌细胞中的动脉粥样硬化机制图谱 |
Albarran-Juarez, J. |
PDF |
N/A |
Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease |
| 表面重塑和细胞-基质相互作用的反转是霍乱弧菌生物膜中社群识别和分散的基础 |
Moreau, A. P. |
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N/A |
Surface remodeling and inversion of cell-matrix interactions underlies community recognition and dispersal in Vibrio cholerae biofilms |
| 通过招募特异性泛素连接酶研究蛋白质降解性 |
Shade, O. |
PDF |
N/A |
Investigating Protein Degradability through Site-Specific Ubiquitin Ligase Recruitment |
| 脂质驱动的SRC自缔合作用调节其转化能力 |
Mohammad Jabeen, I.-L. |
PDF |
N/A |
Lipid-driven SRC self-association modulates its transformation capacity |
| 具有变异活性位点的古菌核糖体结构 |
Nissley, A. J. |
PDF |
N/A |
Structure of an Archaeal Ribosome with a Divergent Active Site |