| 从单细胞的动力学和几何结构中学习细胞特异性网络 |
Zhang, S. Y. |
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N/A |
Learning cell-specific networks from dynamics and geometry of single cells |
| 计算机模拟兔眼和人眼中玻璃体内注射贝伐单抗后的药物分布 |
Chowdhury, J. M. |
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N/A |
Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes |
| 用等效电路解释神经可塑性：一种机制性视角 |
Nilsson, M. N. P. |
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N/A |
Explaining neuroplasticity using equivalent circuits: A mechanistic perspective |
| SNP分配用于估计遗传力（SAFE-h2）：一种用于探索表型基因组起源的工具，用于使用仅加性等位基因效应或加性和非加性等位基因效应估计SNP遗传力 |
Darbani, B. |
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N/A |
SNP Allocation For Estimating Heritability (SAFE-h2): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects |
| 通过高分辨率冷冻电镜结构揭示的APC/C的新结构特征：apo-APC/C和APC/C CDH1:EMI1复合物的结构 |
Hoefler, A. |
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N/A |
New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C CDH1:EMI1 complex |
| 致幻剂5-HT2A受体激动作用：神经元特征与神经血管耦合的改变。 |
Padawer-Curry, J. A. |
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N/A |
Psychedelic 5-HT2A receptor agonism: neuronal signatures and altered neurovascular coupling. |
| 海马中三种中间神经元群体的绝对数量及所有GABA能突触的绝对数量 |
Takacs, V. |
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N/A |
Absolute number of three populations of interneurons and all GABAergic synapses in the human hippocampus |
| 膜电位介导细胞对机械压力的响应 |
Mukherjee, A. |
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N/A |
Membrane potential mediates the cellular response to mechanical pressure |
| 粘附斑衍生的液-液相分离调控mRNA翻译 |
Kumar, A. |
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N/A |
Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation |
| TRPV1和TRPM2在温暖温度检测中的不同作用 |
Abd El Hay, M. Y. |
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N/A |
Diverging roles of TRPV1 and TRPM2 in warm-temperature detection |
| 无细胞优化生产原卟啉IX |
Garcia, D. C. |
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N/A |
Cell-Free Optimized Production of Protoporphyrin IX |
| 短链脂肪酸代谢产物丙酸和丁酸是独特的表观遗传调控因子，连接着饮食、代谢和基因表达。 |
Nshanian, M. |
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N/A |
Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression |
| 基于逻辑的生物网络建模与Netflux |
Clark, A. P. |
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N/A |
Logic-based modeling of biological networks with Netflux |
| 利用大型语言模型揭示人脑中的多层次和多模态语义表征 |
Nakagi, Y. |
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N/A |
Unveiling Multi-level and Multi-modal Semantic Representations in the Human Brain using Large Language Models |
| 抗漂移姿态追踪器（ADPT）：一种基于Transformer的网络，用于跨物种的稳健动物姿态估计 |
Tang, G. |
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N/A |
Anti-drift pose tracker (ADPT): A transformer-based network for robust animal pose estimation cross-species |
| 所有细菌基因组 - 已组装、可用且可搜索的细菌基因组数据库 |
Hunt, M. |
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N/A |
AllTheBacteria - all bacterial genomes assembled, available and searchable |
| 患者来源的ccRCC类器官单细胞中异质性和新型转录本的表达 |
Karakulak, T. |
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N/A |
Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids |
| 在变暖和干燥的气候条件下，热带干旱森林树木的叶部和生殖物候的量和时间变化 |
Lai, H. R. |
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N/A |
Changes in quantity and timing of foliar and reproductive phenology of tropical dry-forest trees under a warming and drying climate |
| 在主动舔食的小鼠中，皮层对味觉和温度信号的编码 |
Nash, A. N. |
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N/A |
Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice |
| 受损的卵黄囊NAD代谢会破坏小鼠胚胎发育，这与人类出生缺陷有关。 |
Bozon, K. |
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N/A |
Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects |
| 一个用于抗体序列理解的生成基础模型 |
Barton, J. |
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N/A |
A generative foundation model for antibody sequence understanding |
| 比较群体基因组学揭示了西南太平洋热液喷口区一致的次级缝合带 |
Tran Lu Y, A. |
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N/A |
Comparative population genomics unveils congruent secondary suture zone in Southwest Pacific Hydrothermal Vents |
| iHDSel软件：利用Price方程和群体稳定性指数检测与选择性清除相符的基因组模式。以SARS-CoV-2为例。 |
Carvajal-Rodriguez, A. |
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N/A |
iHDSel software: The Price equation and the population stability index to detect genomic patterns compatible with selective sweeps. An example with SARS-CoV-2. |
| 对秀丽隐杆线虫中Smad和Schnurri转录因子的全基因组分析显示了它们广泛的相互作用，并在胶原蛋白分泌中发挥功能。 |
Vora, M. |
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N/A |
Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion |
| 开源自动化通用高内涵多重荧光RNA原位分析（AURA）协议 |
Descarpentrie, J. |
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N/A |
Protocol for open-source Automated Universal high-content multiplex fluorescence for RNA in situ Analysis (AURA) |
| 草莓COP9信号体FvCSN5A通过促进多胺氧化酶FvPAO5的降解，调控植物发育和果实成熟，从而控制多胺和H2O2的稳态。 |
Huang, Y. |
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N/A |
Strawberry COP9 signalosome FvCSN5A regulates plant development and fruit ripening by facilitating polyamine oxidase FvPAO5 degradation to control polyamine and H2O2 homeostasis |
| 在小鼠中，绿茶化合物在饮用绿茶后的血浆中出现的情况受到肠道微生物群的调节。 |
Sterrett, J. D. |
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N/A |
Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice |
| 空间变异竞争导致植物适应性和分布对环境梯度的反应不匹配 |
Hayashi, K. T. |
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N/A |
Spatially variable competition contributes to mismatched responses of plant fitness and occurrence to environmental gradients |
| 来自韩国都湖组（中新世）的新鲣鱼标本（属名Auxis） |
Suh, D. |
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N/A |
A new tuna specimen (Genus Auxis) from the Duho Formation (Miocene) of South Korea |
| 细胞类型特异性调控TOR介导的微管乙酰化预测Yki丢失诱导的果蝇鳞状细胞癌 |
Bhattacharya, R. |
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N/A |
Cell-Type-Specific Regulation of TOR-Mediated Microtubule Acetylation Predicts Yki Loss-Induced Squamous Cell Carcinoma in Drosophila |
| 是我还是火车在动？人类在平衡控制中通过一种非线性反馈机制来解决感官冲突。 |
Asslaender, L. |
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N/A |
Is it me or the train moving? Humans resolve sensory conflicts with a nonlinear feedback mechanism in balance control |
| 操作性酒精自我给药以一种驱动药物强化特性的方式，靶向含有GluA2的AMPAR表达和伏隔核中的突触活动。 |
Faccidomo, S. |
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N/A |
Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug |
| 不活动介导的分子适应：从体力活动减少的临床前模型中获得的见解 |
Meyer, A. |
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N/A |
Inactivity-mediated molecular adaptations: insights from a pre-clinical model of physical activity reduction |
| C57BL/6J小鼠在家庭笼中饮用乙醇和操作性自我给药方面的性别差异，但谷氨酸AMPAR活性调节的等效性 |
Faccidomo, S. |
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N/A |
Sex Differences in Home-Cage Ethanol Drinking and Operant Self-Administration in C57BL/6J Mice but Equivalent Regulation by Glutamate AMPAR Activity |
| 利用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层特定层区域边界图 |
Autio, J. A. |
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N/A |
Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI |
| 通过完全自主的HABITS系统实现新颖且优化的鼠标行为：家庭笼辅助行为创新与测试系统 |
Yu, B. |
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N/A |
Novel and optimized mouse behavior enabled by fully autonomous HABITS: Home-cage Assisted Behavioral Innovation and Testing System |
| Pannexin-2 缺陷破坏视觉通路并导致斑马鱼眼部缺陷 |
Shanbhag, R. |
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N/A |
Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish |
| 血液培养物中含有遗传多样性的白色念珠菌菌株，这些菌株在棘白菌素耐药性和毒力方面可能存在差异。 |
Fleres, G. |
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N/A |
Blood cultures contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and virulence |
| 高度多孔的颗粒状水凝胶，通过静电纺丝水凝胶纤维增强，以实现长期稳定性 |
Whitewolf, J. |
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N/A |
Highly porous granular hydrogels reinforced by electrospun hydrogel fibers for long-term stability |
| 化石记录中稀疏时间序列的反应规范适应度峰值追踪 |
Ergon, R. |
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N/A |
Reaction norm fitness peaks tracking applied on sparse time series in the fossil record |
| 岛屿人口统计学：哥特兰岛标志性金雕的繁殖动态及驱动因素 |
Singh, N. J. |
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N/A |
Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles |
| 无标记鸟枪法蛋白质组学中监测宿主细胞蛋白的MS/MS搜索算法比较分析，采用捕获离子淌度和ddaPASEF技术 |
Khalil, S. |
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N/A |
Comparative analysis of MS/MS search algorithms in label-free shotgun proteomics for monitoring host-cell proteins using trapped ion mobility and ddaPASEF |
| 雌蛾将植物的声发射纳入其产卵决策中 |
Seltzer, R. |
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N/A |
Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision |
| 新生转录本O-MAP揭示了由RBM20和TTN RNA构建的单基因位点亚核区室的分子结构 |
Kania, E. E. |
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N/A |
Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA |
| 抑郁症和焦虑症中基底前脑对内在脑网络的调控改变 |
Jamieson, A. J. |
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N/A |
Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders |
| 在人类和小鼠胰岛素中，一种翻译后将半胱氨酸转化为丝氨酸的转变，产生了一种糖尿病新表位。 |
Srivastava, N. |
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N/A |
A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope |
| 资源环境塑造了人类阴道微生物群的组成和稳定性。 |
Kamiya, T. |
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N/A |
Resource landscape shapes the composition and stability of the human vaginal microbiota |
| ER Ca2+水平通过调节L型Ca2+通道活性来控制神经调质的分泌。 |
Hoogstraaten, R. I. |
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N/A |
ER Ca2+-levels control neuromodulator secretion by regulating L-type Ca2+-channel activity |
| 在一年的时间里，孟加拉国各地的霍乱弧菌谱系和泛基因组多样性存在地理差异。 |
Qin, C. |
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N/A |
Vibrio cholerae lineage and pangenome diversity varies geographically across Bangladesh over one year |
| 有丝分裂CIP2A-TOPBP1轴促进有丝分裂途径在MiDAS和MMEJ之间的选择。 |
Martin, P. R. |
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N/A |
The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ |
| 重度抑郁症外周血单个核细胞神经免疫网络中突触相关基因的失调 |
Adri, A. |
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N/A |
Dysregulation of synaptic-related genes within neuroimmune networks of peripheral blood mononuclear cells in major depressive disorder |
| 比较用于预测急性髓系白血病患者突变状态的机器学习模型，使用RNA测序数据 |
Silva, R. |
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N/A |
Comparing machine learning models for predicting mutation status in Acute Myeloid Leukemia patients using RNA-seq data |
| 加拿大早期职业健康研究人员特征及COVID-19疫情期间的职业倦怠经历 |
Hewko, S. |
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N/A |
Characteristics of early career health researchers and experiences of burnout during the COVID-19 pandemic in Canada |
| 我们是意识的传感器！关于睡眠中的觉醒如何影响梦境回忆的回顾与分析。 |
Stucky, B. |
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N/A |
We are the sensors of consciousness! A review and analysis on how awakenings during sleep influence dream recall. |
| 坦桑尼亚南部伊法卡拉-卢皮罗-曼古拉野生动物管理区的利益相关者对其有效性的看法 |
Tarimo, L. J. |
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N/A |
Stakeholder perspectives on the effectiveness of the Ifakara-Lupiro-Mang'ula Wildlife Management Area in Southern Tanzania |
| 对GWAS汇总统计数据的稀疏矩阵分解，能够稳健地处理样本共享问题，从而提高对具有多样遗传结构的因素的检测和解释能力。 |
Omdahl, A. R. |
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N/A |
Sparse matrix factorization of GWAS summary statistics robust to sample sharing improves detection and interpretation of factors with diverse genetic architectures |
| 量化颅骨整骨手法对阿尔茨海默病野生型和转基因大鼠模型的影响 |
Hines, D. |
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N/A |
Effect of quantified cranial osteopathic manipulation on wild type and transgenic rat models of Alzheimer's disease |
| 经典三叉神经痛患者的脑老化 |
Cruz-Almeida, Y. |
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N/A |
Brain Aging Among Individuals with Classical Trigeminal Neuralgia |
| 在实体瘤基质中异常表达的X型胶原蛋白与上皮-间质转化、免疫抑制和促转移通路、骨髓基质细胞特征以及不良的生存预后相关。 |
Famili-Youth, E. H. H. |
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N/A |
Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis |
| 饮食和非酶氧化固醇在子痫前期胎盘中的积累：对妊娠并发症中胆固醇动态的见解 |
Zou, L. |
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N/A |
Accumulation of Dietary and Non-Enzymatic Oxysterols in Preeclamptic Placentas: Insights into Cholesterol Dynamics in Pregnancy Complications |
| 母亲运动方式对婴儿脐带血蛋白质组的影响 |
Jevtovic, F. |
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N/A |
Effects of maternal exercise modes on infant cord blood proteome |
| 小窝蛋白-1和水通道蛋白-4作为遗传性脑淀粉样血管病中纤维蛋白原驱动脑血管病理的介质 |
Singh, V. |
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N/A |
Caveolin-1 and Aquaporin-4 as Mediators of Fibrinogen-Driven Cerebrovascular Pathology in Hereditary Cerebral Amyloid Angiopathy |
| 使用高灵敏度磷脂酰丝氨酸结合试剂在体内评估细胞外囊泡的周转 |
Flaskamp, L. |
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N/A |
Assessing Extracellular Vesicle Turnover In vivo Using Highly Sensitive Phosphatidylserine-Binding Reagents |
| 在有鳞目深系谱中，核与线粒体氧化磷酸化复合体亚基的趋同进化证据 |
Wallnoefer, O. |
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N/A |
Evidence of convergent evolution in the nuclear and mitochondrial OXPHOS subunits across the deep lineages of Squamata |
| 通过张量分解重构RNA-断层扫描转录组的三维空间结构 |
Song, T. |
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N/A |
Reconstructing 3D Spatial Structures of RNA-Tomography Transcriptomes by Tensor Factorization |
| 全蛋白质组反向分子对接揭示叶酸受体作为PFAS诱导神经发育毒性的介质 |
Kong, A. X. |
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N/A |
Proteome-wide reverse molecular docking reveals folic acid receptor as a mediator of PFAS-induced neurodevelopmental toxicity |
| 调控Koisio技术生产的流体对血管外膜间质液流动的影响及其通过输送艾司洛尔对心率的作用 |
Li, B. |
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N/A |
Regulating of Koisio technology-produced fluid on Vascular Adventitial Interstitial Fluid flow and its Effect on heart rate by delivering Esmolol |
| 蛋白质-蛋白质相互作用是遗传相互作用网络中上位性的主要来源 |
Castellanos-Girouard, X. |
PDF |
N/A |
Protein-protein interaction is a major source of epistasis in genetic interaction networks |
| 坏死性脑膜脑炎中的星形胶质细胞功能障碍、脱髓鞘和结节性炎症 |
Hernandez, S. I. |
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N/A |
Astroglial Dysfunction, Demyelination and Nodular inflammation in Necrotizing Meningoencephalitis |
| 在竞争性生态系统中多重稳定平衡的结构 |
Taylor, W. |
PDF |
N/A |
On the structure of multiple stable equilibria in competitive ecological systems |
| scPrediXcan将深度学习和单细胞数据的进展整合到一个强大的细胞类型特异性转录组关联研究框架中。 |
Zhou, Y. |
PDF |
N/A |
scPrediXcan integrates advances in deep learning and single-cell data into a powerful cell-type-specific transcriptome-wide association study framework |
| 底物和产物选择性尼龙水解酶的鉴定与表征 |
Drufva, E. |
PDF |
N/A |
Identification and characterization of substrate- and product-selective nylon hydrolases |
| 金属水解酶的计算设计 |
Kim, D. |
PDF |
N/A |
Computational Design of Metallohydrolases |
| 大鼠颞下颌关节中锌特异性髁突区的硫物种 |
Lee, B. H. |
PDF |
N/A |
Sulfur-species in Zinc-specific Condylar Zones of a Rat Temporomandibular Joint |
| PYR1生物传感器驱动的克鲁维酵母基因组范围CRISPR筛选，以提高单萜类化合物生产 |
Robertson, N. R. |
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N/A |
PYR1 biosensor-driven genome-wide CRISPR screens for improved monoterpenoid production in Kluyveromyces marxianus |
| 心脏组织中早期后去极化驱动的心律失常机制 |
Stein, J. |
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N/A |
Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue |
| 快速反应特质在感觉运动皮层中的Mu和Beta节律效应在提示前和运动执行期间表现出双重分离 |
Kamali, S. |
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N/A |
Mu and beta power effects of fast response trait double dissociate during precue and movement execution in the sensorimotor cortex |
| 通信子空间与人工神经网络的训练相一致 |
Poggi, P. G. |
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N/A |
Communication subspaces align with training in ANNs |
| 紫外线诱导的DNA修复机制及其对大肠杆菌突变性和培养能力的影响 |
Ghosh, S. |
PDF |
N/A |
UV-Induced DNA Repair Mechanisms and Their Effects on Mutagenesis and Culturability in Escherichia coli |
| 布氏锥虫的糖体ATP依赖性磷酸果糖激酶在体内类似条件下，在细胞内以糖异生方向进行操作。 |
Plazolles, N. |
PDF |
N/A |
The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates in the gluconeogenic direction in cellulo under in vivo-like conditions |
| Mcm3中一个必需的核定位序列的序列特异性 |
Wang, Z. |
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N/A |
Sequence specificity of an essential nuclear localization sequence in Mcm3 |
| 生物膜形成和生态位适应在塑造远距离运输的尘埃微生物群落中起着基础性作用。 |
Lang-Yona, N. |
PDF |
N/A |
Biofilm Formation and Niche Adaptation Play Fundamental Role in Shaping Long-Distance Transported Dust Microbial Community |
| 自然发生的、菌株特异性的鲍曼不动杆菌IV型菌毛回缩缺陷促进了生物膜的形成 |
Yu, Y. |
PDF |
N/A |
Naturally-occurring, strain-specific defects in the retraction of Acinetobacter baumannii type IV pili promote biofilm formation |
| 揭示可可病原菌Moniliophthora perniciosa对嘧菌酯抗性的新机制 |
do Prado, P. F. V. |
PDF |
N/A |
Unveiling novel mechanisms of strobilurin resistance in the cacao pathogen Moniliophthora perniciosa |
| 5500年前贝加尔湖狩猎采集者的致命瘟疫爆发 |
Macleod, R. |
PDF |
N/A |
Lethal Plague Outbreaks in Lake Baikal Hunter-gatherers 5500 Years Ago |
| 基于活动的增强型碱基编辑器突变扫描的选择 |
Kaplan, E. G. |
PDF |
N/A |
Activity-based selection for enhanced base editor mutational scanning |
| 使用MxP(R) Quant 500试剂盒对人血和啮齿动物血液进行标准化代谢组学和脂质组学分析的实验室间比较 |
Zararsiz, G. E. |
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N/A |
Interlaboratory comparison of standardised metabolomics and lipidomics analyses in human and rodent blood using the MxP(R) Quant 500 kit |
| 通过着丝粒DNA序列增强的力传递至内着丝粒 |
Miedlar, E. |
PDF |
N/A |
Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences |
| 基于机制的方法在设计针对无义突变疾病的个性化联合疗法中的应用 |
Bhat, S. |
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N/A |
Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases |
| 动物编码的非核糖体途径合成bursatellin类似物。 |
Schmidt, E. W. |
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N/A |
Animal-encoded nonribosomal pathway to bursatellin analogs. |
| RhoA通过其EF手结构域别构激活磷脂酶Cε |
Ohri, V. |
PDF |
N/A |
RhoA Allosterically Activates Phospholipase Cε via its EF Hands |
| 杨树：一个系统发育学分析流程 |
Krishnakumar, R. |
PDF |
N/A |
Poplar: A Phylogenetics Pipeline |
| 通过基于同源性和表示的分层聚类探索大型蛋白质序列空间 |
Chen, J. Z. |
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N/A |
Exploring large protein sequence space through homology- and representation-based hierarchical clustering |
| 利用大型语言模型增强基因集富集分析 |
Zhu, J. |
PDF |
N/A |
Enhancing Gene Set Overrepresentation Analysis with Large Language Models |
| 在科学会议上无法理解的图表 |
Faulkes, Z. |
PDF |
N/A |
Uninterpretable graphs at a scientific conference |
| 外周CGRP参与偏头痛的脑电网络活动 |
Johnson, M. S. |
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N/A |
Peripheral CGRP engages brain-wide electrical network activity of migraine |
| 社交焦虑改变了电影观看期间心智理论激活和跨受试者神经变异性的情况 |
Mangnus, M. |
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N/A |
Social Anxiety Alters Theory of Mind Activation and Intersubject Neural Variability During Movie Viewing |
| 下调星形胶质细胞C3的产生可缓解tau病模型中的神经元线粒体功能障碍 |
Lei, C. |
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N/A |
Downregulation of astrocytic C3 production alleviates neuronal mitochondrial dysfunction in tauopathy models |
| 学习后的休息有助于记忆巩固，并能逆转3xTg-AD小鼠在新环境中空间重定向能力的损伤。 |
Stimmell, A. C. |
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N/A |
Resting After Learning Facilitates Memory Consolidation and Reverses Spatial Reorientation Impairments in 'New Surroundings' in 3xTg-AD Mice |
| FreeSurfer版本对帕金森病结构神经影像分析的影响 |
Sokolowski, A. |
PDF |
N/A |
The impact of FreeSurfer versions on structural neuroimaging analyses of Parkinson's disease |
| 通过单细胞电感耦合等离子体质谱法快速精确量化淋巴细胞铁含量 |
Holdship, P. |
PDF |
N/A |
Rapid and precise quantification of lymphocyte iron content by single cell inductively coupled plasma mass spectrometry |
| 约氏疟原虫的特化S型核糖体增强了宿主到媒介的疟疾传播 |
McGee, J. P. |
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N/A |
Specialized S-type ribosomes of Plasmodium yoelii enhance host-to-vector malaria transmission |
| 在利什曼原虫（Leishmania major）中，核DNA复制依赖于每个染色体上的一个组成性起始点，并辅以数千次随机起始事件。 |
Damasceno, J. D. |
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N/A |
Nuclear DNA replication in Leishmania major relies on a single constitutive origin per chromosome supplemented by thousands of stochastic initiation events |
| Cochlin的缺失导致肌腱结构和功能的损伤 |
Adjei-Sowah, E. |
PDF |
N/A |
Loss of Cochlin drives impairments in tendon structure and function |
| SARS-CoV-2对宿主胆固醇的操控 |
Doyle, A. |
PDF |
N/A |
Manipulation of Host Cholesterol by SARS-CoV-2 |
| 纳米孔数据类型、碱基识别与组装算法比较：单个MinION流式细胞仪的全植物基因组组装及甲基化分析 |
Martin, S. |
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N/A |
A Comparison of Nanopore Data Types, Basecalling, and Assembly Algorithms: Whole Plant Genome Assembly and Methylation Analysis from a Single MinION Flow cell |
| 光亲和标记技术助力在天然细胞中转录组范围内鉴定剪接调控小分子-RNA结合事件 |
Shah, R. |
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N/A |
Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells |
| 驱动神经退行性溶酶体贮积障碍模型中小胶质细胞表观遗传和转录反应的机制 |
Balak, C. D. |
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N/A |
Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model |
| 内嗅皮层中的反复抑制性动态支持模式分离 |
Zheng, Y. |
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N/A |
Recurrent Inhibitory Dynamics in the Entorhinal Cortex Support Pattern Separation |
| 7特斯拉下SNR高效的全脑伪连续动脉自旋标记灌注成像 |
Woods, J. G. |
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N/A |
SNR-Efficient Whole-Brain Pseudo-Continuous Arterial Spin Labeling Perfusion Imaging at 7 Tesla |
| 转铁蛋白受体介导的血液-脑屏障运输在早期发育中升高，但在成年衰老过程中保持稳定。 |
Torres, V. O. |
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N/A |
Transferrin receptor-mediated transport at the blood-brain barrier is elevated in early development but maintained across adult aging |
| 多尺度基于云的神经电生理分析与可视化管道 |
Geng, J. |
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N/A |
Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization |
| 在哺乳动物皮层胶质发生和胶质瘤发生过程中，通过Olig1/2调控少突胶质前体细胞与嗅球中间神经元的命运 |
TIAN, Y. |
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N/A |
Orchestrating the Acquisition of Oligodendrocyte Precursor Cell versus Olfactory Bulb Interneuron Fates through Olig1/2 during Mammalian Cortical Gliogenesis and Gliomagenesis |
| 解码嗅结节中的中脑边缘多巴胺传递及其通过神经化学感应和化学遗传学对甲基苯丙胺反应的贡献 |
Bhimani, R. V. |
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N/A |
Decoding mesolimbic dopamine transmission in the olfactory tubercle and its contribution to methamphetamine responses through neurochemical sensing and chemogenetics |
| 姜黄素通过CDK5/p35信号通路减轻小胶质细胞介导的慢性神经性疼痛 |
Tong, F. |
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N/A |
Curcumin attenuates microglia-mediated chronic neuropathic pain through CDK5 /p35 signaling pathway |
| 空间工作记忆期间发作间期的尖波携带有助于或干扰空间表征，并对表现产生相反的影响。 |
Yi, J. D. |
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N/A |
Interictal spikes during spatial working memory carry helpful or distracting representations of space and have opposing impacts on performance. |
| 黑质网状部至中缝背核的谷氨酸能投射促进小鼠的社会等级 |
Fan, Y. |
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N/A |
The Glutamatergic Projection from the Substantia Nigra Pars Reticulata to the Dorsal Raphe Nucleus Facilitates Social Hierarchy in Mice |
| 受损的蛋白酶体引发线粒体DNA释放，激活小鼠脑中的cGAS-STING信号通路并导致坏死。 |
Dwamena, A. |
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N/A |
Impaired proteasome induces mitochondrial DNA release to activate the cGAS-STING signaling pathway and cause necroptosis in mouse brain |
| 基于MRI的人类神经发育新生物型与冲动行为表现相关 |
Zhou, Z. |
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N/A |
Novel MRI-based Biotypes of Human Neurodevelopment associated with Impulsivity performance |
| 不同频率的胡须刺激揭示了清醒大鼠感觉系统中功能性磁共振成像信号的非均匀调制 |
Paasonen, J. |
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N/A |
Whisker stimulation with different frequencies reveals non-uniform modulation of functional magnetic resonance imaging signal across sensory systems in awake rats |
| 沙漠蝗虫听觉功能的性别差异 |
Austin, T. |
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N/A |
Sex differences in auditory function of the desert locust |
| 在少突胶质细胞命运决定期间，procaspase-3的瞬时上调 |
Kamen, Y. |
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N/A |
Transient upregulation of procaspase-3 during oligodendrocyte fate decisions |
| YORU：基于用户定义动物外观的深度学习社交行为检测 |
YAMANOUCHI, H. M. |
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N/A |
YORU: social behavior detection based on user-defined animal appearance using deep learning |
| Nrf2 在成年小鼠大脑中以细胞类型特异性的方式调控体内平衡转录特征和炎症反应。 |
He, X. |
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N/A |
Nrf2 controls homeostatic transcriptional signatures and inflammatory responses in a cell-type specific manner in the adult mouse brain |
| 间充质细胞衍生的细胞外囊泡改善了恒河猴工作记忆的年龄相关性缺陷以及脑部MRI和脑脊液中神经退行性变的体内生物标志物。 |
Mackie, E. C. |
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N/A |
Mesenchymal Cell-Derived Extracellular Vesicles Ameliorate Age-Related Deficits in Working Memory as well as Brain MRI and CSF in vivo Biomarkers of Neurodegeneration in Rhesus Monkeys. |
| 中脑多巴胺D2R调节与威胁相关事件的显著性 |
Castell, L. |
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N/A |
Midbrain dopamine D2R regulates the salience of threat-related events |
| 在自我思考期间，mPFC中认知过程的分解 |
Levorsen, M. |
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N/A |
Decomposing Cognitive Processes in the mPFC During Self-Thinking |
| 低频皮层活动反映了依赖于语境的词序列解析 |
Chen, H. |
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N/A |
Low-frequency Cortical Activity Reflects Context-dependent Parsing of Word Sequences |
| 小脑中的神经计算向量微积分 |
Fakharian, M. A. |
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N/A |
A vector calculus for neural computation in the cerebellum |
| 成人脑膜的整合分层图谱 |
Degenhard, T. |
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N/A |
An integrative layer-resolved atlas of the adult human meninges |
| 人类上行觉醒系统皮层下核团编码预期奖励，但不预测后续记忆 |
Lloyd, B. |
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N/A |
Subcortical nuclei of the human ascending arousal system encode anticipated reward but do not predict subsequent memory |
| 基于钙的输入时序学习 |
Kamalabad, S. S. |
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N/A |
Calcium-based input timing learning |
| 果糖-2,6-二磷酸恢复了运动神经元疾病中TDP-43病理驱动的基因组修复缺陷 |
Mitra, J. |
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N/A |
Fructose-2,6-bisphosphate restores TDP-43 pathology-driven genome repair deficiency in motor neuron diseases |
| 果蝇神经元的独特非对称分支优化了时间树突计算 |
Chou, P.-J. |
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N/A |
Unique Asymmetric Branching of Drosophila Neurons Optimizes Temporal Dendritic Computation |
| 猕猴外侧膝状体神经元的单细胞转录组分析揭示了新的亚群 |
Sun, S. H. |
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N/A |
Single-cell transcriptomic analysis of macaque LGN neurons reveals novel subpopulations |
| 与加速的产后发育长期功能连接组相关的自发脑动力学 |
Ma, L. |
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N/A |
Spontaneous Brain Dynamics Associated With Acceleration Of Longterm Functional Connectome In Postnatal Development |
| 深度神经网络解释了听觉皮层的尖峰活动 |
Ahmed, B. |
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N/A |
Deep Neural Networks Explain Spiking Activity in Auditory Cortex |
| 肌萎缩侧索硬化症（ALS）大脑和脊髓中神经免疫区室的单细胞转录组图谱 |
Tuddenham, J. |
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N/A |
Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord |
| 帕金森病患者在在线和离线运动序列学习中受损和增强 |
Van Roy, A. |
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N/A |
Impaired online and enhanced offline motor sequence learning in individuals with Parkinson's disease |
| 在做出感知决策以在不同行动之间进行选择时，人类会预见运动控制需求的结果。 |
Leroy, E. |
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N/A |
Humans anticipate the consequences of motor control demands when making perceptual decisions between actions |
| 降低蓝斑核去甲肾上腺素能信号传导至脊髓星形胶质细胞亚群是应激诱发疼痛易化所必需的。 |
Kawanabe-Kobayashi, R. |
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N/A |
Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation |
| 价值对与任务无关的听觉失配负波无影响 |
Hutchinson, B. T. |
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N/A |
No Effect of Value on the Task Irrelevant Auditory Mismatch Negativity |
| 病理性微电路在患者海马切片中启动癫痫样事件 |
Elliott, M. |
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N/A |
Pathological microcircuits initiate epileptiform events in patient hippocampal slices |
| 工作记忆中感觉和运动内容的动态优先级排序 |
Echeverria-Altuna, I. |
PDF |
N/A |
Dynamic prioritisation of sensory and motor contents in working memory |
| 星形胶质细胞连接蛋白43的磷酸化作用在轻度创伤性脑损伤后对癫痫易感性的影响 |
Munoz-Ballester, C. |
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N/A |
Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild Traumatic Brain Injury |
| 恢复精神分裂症中的突触平衡：基于丘脑-皮层电导模型的见解。 |
Berndt, L. C. S. |
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N/A |
Restoring Synaptic Balance in Schizophrenia: Insights from a thalamo-cortical conductance-based model. |
| 大鼠体感皮层血液流动动力学的建模 |
Battini, S. |
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N/A |
Modeling of blood flow dynamics in the rat somatosensory cortex |
| 空间转录组学分析鉴定出一种表达SERPINA3的星形胶质细胞状态，与人类神经炎斑微环境相关 |
Karaahmet, B. |
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N/A |
Spatial Transcriptomic Analysis Identifies a SERPINA3-Expressing Astrocytic State Associated with the Human Neuritic Plaque Microenvironment |
| 硫脂缺乏引起的星形胶质细胞增生和髓鞘脂质稳态失调与Trem2介导的微胶质细胞激活无关。 |
Mittra, N. |
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N/A |
Sulfatide deficiency-induced astrogliosis and myelin lipid dyshomeostasis are independent of Trem2-mediated microglial activation |
| miR-29a调控对成年大脑记忆稳定性的双向影响 |
Viglione, A. |
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N/A |
Bidirectional Impact of miR-29a modulation on Memory Stability in the Adult Brain |
| 一种基于PET的功能激活和分子连接识别的统一方法，借助功能PET工具箱实现 |
Hahn, A. |
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N/A |
A Unified Approach for Identifying PET-based Neuronal Activation and Molecular Connectivity with the functional PET toolbox |
| 由特定亚型TrkB-T1序列建立的相互作用调控中风中的炎症反应和神经毒性 |
Ugalde-Trivino, L. |
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N/A |
Interactions established by isoform-specific TrkB-T1 sequences govern inflammatory response and neurotoxicity in stroke |
| 使用潜在状态逆强化学习建模复杂动物行为 |
Jha, A. |
PDF |
N/A |
Modeling Complex Animal Behavior with Latent State Inverse Reinforcement Learning |
| 年长即有序：皮层自发活动的熵减少标志着健康衰老 |
Chang, D. |
PDF |
N/A |
Older is Order: Entropy reduction in cortical spontaneous activity marks healthy aging |
| 脑功能网络连接插值法表征了神经精神连续谱与异质性 |
Li, X. |
PDF |
N/A |
Brain functional network connectivity interpolation characterizes neuropsychiatric continuum and heterogeneity |
| 大规模脑干记录中尖峰分类器的比较分析 |
De Preter, C. C. |
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N/A |
Comparative analysis of spike-sorters in large-scale brainstem recordings |
| 多模态探究成年阅读障碍背后的神经认知缺陷 |
Cara, C. |
PDF |
N/A |
Multimodal investigation of the neurocognitive deficits underlying dyslexia in adulthood |
| 性相关基因表达在循环雌性大鼠后内侧杏仁核中的表现以及催乳素对雌性大鼠交配行为的影响 |
Buhler, L. |
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N/A |
SEX-RELATED GENE EXPRESSION IN THE POSTERODORSAL MEDIAL AMYGDALA OF CYCLING FEMALE RATS ALONG WITH PROLACTIN MODULATION OF LORDOSIS BEHAVIOR |
| 特征相似性：一种敏感的方法，用于捕捉脑区和网络的功能相互作用，以支持灵活的行为 |
Wang, X. |
PDF |
N/A |
Feature similarity: a sensitive method to capture the functional interaction of brain regions and networks to support flexible behavior |
| 核糖体丰度，而非旁系同源基因组成，对生殖系发育至关重要 |
Grobicki, K. Z. A. |
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N/A |
Ribosome abundance, not paralogue composition, is essential for germline development |
| 钙信号传导在小鼠胚胎的前部模式形成中是必需的。 |
Stower, M. |
PDF |
N/A |
Calcium signalling is required for anterior patterning in the mouse embryo |
| 在终末期红细胞生成过程中，血红蛋白的高效生产依赖于TENT5C多聚腺苷酸聚合酶与LARP4/5的协同作用。 |
Mazur, M. |
PDF |
N/A |
Efficient globin production during terminal erythropoiesis depends on the synergistic action of TENT5C poly(A) polymerase and LARP4/5 |
| PP2A磷酸酶在Hippo信号调控中具有双重作用 |
Sekar, A. |
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N/A |
A Dual Role for the PP2A Phosphatase in Hippo Signalling Regulation |
| Hox13通过与Fgf10和Tbx4相互作用调控蝾螈后肢芽外突的新功能 |
Tozawa, S. |
PDF |
N/A |
Novel function of Hox13 in regulating outgrowth of the newt hindlimb bud through interaction with Fgf10 and Tbx4 |
| 及时的神经发生能够促进神经元分层过程中核包装顺序的增加 |
Ferme, L. C. |
PDF |
N/A |
Timely neurogenesis enables increased nuclear packing order during neuronal lamination |
| Sox9和Nfi转录因子调控多巴胺前体细胞中神经发生和室管膜成熟的时机 |
Lahti, L. |
PDF |
N/A |
Sox9 and Nfi transcription factors regulate the timing of neurogenesis and ependymal maturation in dopamine progenitors |
| Koolen-de Vries综合征的致病基因KANSL1对于运动纤毛的生成是必需的。 |
Schmidt, J. D. |
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N/A |
Koolen-de Vries Syndrome causal gene KANSL1 is required for motile ciliogenesis |
| 利用机器智能进行回溯性运动分析，预测情绪障碍的潜在风险 |
Jung, W. |
PDF |
N/A |
Back-to-the-future motion analysis using machine intelligence predicts the potential risk of mood disorders |
| 黑猩猩手势序列中下一个元素的可预测性 |
Mielke, A. |
PDF |
N/A |
Predictability of next elements in chimpanzee gesture sequences |
| 刺激的不确定性和相对奖励率决定了感知决策中的适应性反应 |
de la Cuesta-Ferrer, L. |
PDF |
N/A |
Stimulus uncertainty and relative reward rates determine adaptive responding in perceptual decision-making |
| 在乳腺癌诱导骨痛的小鼠模型中，数字通风笼（Digital Ventilated Cages）内的轮跑活动受损，而家庭笼内的活动未受影响。 |
Hopkins, C. |
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N/A |
Wheel running, but not home cage activity in Digital Ventilated Cages(R) is impaired in a mouse model of breast cancer-induced bone pain |
| 慢性口服尼古丁对年轻成年早老素-1/2双敲除痴呆模型小鼠的嗅觉功能障碍无改善作用 |
Si, Y. |
PDF |
N/A |
Lack of Ameliorative Effect of Chronic Oral Nicotine on Olfactory Dysfunction in Young Adult Presenilin-1/2 Double Knockout Mice of a Dementia Model |
| 增强牛磺酸摄取的牛磺酸转运蛋白的结构基础缓解细胞衰老 |
Zhang, H. |
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N/A |
Structural basis of augment taurine uptake by taurine transporter alleviating cellular senescence |
| 注意你的光谱：验证同量异位组蛋白肽段形式鉴定时需要注意的要点 |
Hijazi, H. |
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N/A |
Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms |
| 使用表达植酸酶的酿酒酵母减少高粱面团中的抗营养因子植酸 |
Kale, T. |
PDF |
N/A |
Reducing phytate, an antinutritional factor, in sorghum dough using phytase-expressing Saccharomyces cerevisiae |
| 在长达五亿年的进化过程中，顺式调控密码的保守性 |
Ogawa, Y. |
PDF |
N/A |
Conservation of cis-regulatory codes over half a billion years of evolution |
| 驯化对犬科动物中新氨基酸改变突变的选择效应的进化影响 |
G. Amorim, C. E. |
PDF |
N/A |
Evolutionary consequences of domestication on the selective effects of new amino acid changing mutations in canids |
| 一个多组织发育基因表达图谱，旨在理解绵羊表型的生物学基础 |
Zhao, B. |
PDF |
N/A |
A multi-tissue developmental gene expression atlas towards understanding the biological basis of phenotypes in sheep |
| 人类基因组的调控可塑性 |
Srivastava, J. |
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Regulatory plasticity of the human genome |