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贝叶斯球:贝叶斯方法在职业棒球击球员中的整合 Brantley, J. A. PDF N/A Bayesball: Bayesian Integration in Professional Baseball Batters
p53翻译异构体Δ40p53通过调节miR-4671-5p/SGSH轴调控细胞周期 Pal, A. PDF N/A p53 translational-isoform Δ 40p53 regulates cell cycle by modulating the miR-4671-5p/SGSH axis
古代和现代伊比利亚牛的基因组中留下了野牛杂交的遗传遗产 Günther, T. PDF N/A The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle
一种富含棕色脂肪的脂肪因子,ASRA,是一种瘦素受体拮抗剂,能够刺激食欲。 Huang, L. PDF N/A A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite
使用变分自编码器实现AI设计的基因组 Dudek, N. K. PDF N/A Towards AI-designed genomes using a variational autoencoder
通过集体迁徙实现的非遗传性适应 Vo, L. PDF N/A Non-genetic adaptation by collective migration
人类强化学习中对缓慢变化特征的归纳偏置 Hedrich, N. L. PDF N/A An inductive bias for slowly changing features in human reinforcement learning
全脑血流动力学预测人类在睡眠和清醒状态下的神经节律 Jacob, L. P. L. PDF N/A Brainwide hemodynamics predict neural rhythms across sleep and wakefulness in humans
定量超微结构时间线揭示了自噬在细胞核中的作用,并揭示了动力蛋白样蛋白1在核膜中的作用 Mannino, P. J. PDF N/A A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope
调控性ChREBP/14-3-3复合物的分子胶保护β细胞免受糖脂毒性影响。 Katz, L. S. PDF N/A Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.
肾小球弹性与基因表达模式定义了Alport肾病的两个阶段 Yoon, J. PDF N/A Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
BAITSAO:基于语言模型的药物协同分析基础模型构建 Liu, T. PDF N/A BAITSAO: Building A Foundation Model for Drug Synergy Analysis Powered by Language Models
在不同黄鲈(Perca flavescens)种群中,有效种群大小变化背景下发生的平行遗传适应 Yin, X. PDF N/A Parallel genetic adaptation amidst a background of changing effective population sizes in divergent yellow perch (Perca flavescens) populations
心灵字幕:从人脑活动中演化出心理内容的描述性文本 Horikawa, T. PDF N/A Mind Captioning: Evolving descriptive text of mental content from human brain activity
导致精神病的损伤在大脑海马中映射到一条共同的脑回路 Pines, A. R. PDF N/A Lesions that Cause Psychosis Map to a Common Brain Circuit in the Hippocampus
静水压力与肌动蛋白聚合的联合作用驱动内皮尖端细胞迁移和发芽血管生成 Kondrychyn, I. PDF N/A Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis
基于CRISPRi的微胶质细胞自闭症谱系障碍风险基因筛选揭示了ADNP在微胶质细胞内吞作用和突触修剪中的作用 Teter, O. M. PDF N/A CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning
微生物间的相互作用影响抗生素抗性演化的速度和模式。 Zandbergen, L. E. PDF N/A Microbial interactions affect the tempo and mode of antibiotic resistance evolution
理解深度药物反应模型性能的来源揭示了见解和改进 Branson, N. PDF N/A Understanding the Sources of Performance in Deep Drug Response Models Reveals Insights and Improvements
在高分辨率和高准确度下对听觉中脑的神经编码进行建模 Drakopoulos, F. PDF N/A Modeling neural coding in the auditory midbrain with high resolution and accuracy
探究自然脑动力学拓扑结构中的个体差异 Xian, J. PDF N/A Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics
乙烯受体获得和丧失功能突变体揭示了根中依赖于ETR1的转录网络 Khoury, M. G. PDF N/A Ethylene Receptor Gain- and Loss-of-function Mutants Reveal an ETR1-dependent Transcriptional Network in Roots
一种高效预测自然物体感知相似性的高通量方法 Kaniuth, P. PDF N/A A high-throughput approach for the efficient prediction of perceived similarity of natural objects
在异源二倍体和四倍体种群中,基因组预测杂种优势、近交控制和配对分配 Endelman, J. B. PDF N/A Genomic prediction of heterosis, inbreeding control, and mate allocation in outbred diploid and tetraploid populations
活性树突化学突触与间隙连接的细胞外信号之间的二分法 Sirmaur, R. PDF N/A Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions
突触前囊泡循环中的幂律适应 Mikulasch, F. A. PDF N/A Power-law adaptation in the presynaptic vesicle cycle
重复激活视前区接收神经元在室旁核后部介导慢性热诱导的负性情绪效价和过度唤醒状态 Cao, Z. PDF N/A Repeated activation of preoptic area-recipient neurons in posterior paraventricular nucleus mediates chronic heat-induced negative emotional valence and hyperarousal states
交配系统对多个属中谱系分化的影响分析 Xu, K. PDF N/A Analysis of the effects of mating systems on lineage diversification across multiple genera
用于多胺的基因编码荧光报告器 Sharma, P. PDF N/A Genetically encoded fluorescent reporter for polyamines
主要抑郁症的基因年龄差距估计(GAGE):使用基因表达的惩罚性生物年龄模型 Li, Y. PDF N/A Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression
在肿瘤发生过程中,mRNA的等位基因失衡被选择性地保留,这一现象源于表观遗传的改变,并且与预后相关。 Palou-Marquez, G. PDF N/A Allele imbalance in mRNA is selected in tumorigenesis, results from epigenetic alterations and has prognostic relevance
横断面脑龄评估在预测未来脑变化方面存在局限性。 Korbmacher, M. PDF N/A Cross-sectional brain age assessments are limited in predicting future brain change
通过基因组和线粒体数据揭示的濒危物种西伯利亚鼯鼠(Pteromys volans)的种群结构 Ito dos Santos, F. PDF N/A Population structure of the endangered Siberian flying squirrel (Pteromys volans) revealed by genomic and mitochondrial data
弥合秀丽隐杆线虫的连接组与全脑活动之间的差距 Creamer, M. S. PDF N/A Bridging the gap between the connectome and whole-brain activity in C. elegans
过滤点过程可有效捕捉神经电生理记录中的节奏性和宽带功率谱结构 Bloniasz, P. F. PDF N/A Filtered Point Processes Tractably Capture Rhythmic And Broadband Power Spectral Structure in Neural Electrophysiological Recordings
利用光谱流式细胞术对全细胞中核组蛋白H3的翻译后修饰进行分析 Golden, C. S. PDF N/A Nuclear Histone H3 Post-translational Modification Profiling in Whole Cells using Spectral Flow Cytometry
通过拓扑高阶功能连接解析精神分裂症中的整合-分离失衡 Li, Q. PDF N/A Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity
ASCL1介导的染色质结合和基因激活的增殖性与神经元程序具有细胞周期阶段特异性 Beckman, W. F. PDF N/A Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific
LipiDetective - 一种用于在串联质谱中识别分子脂质种类的深度学习模型 Wuerf, V. PDF N/A LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra
代谢物营养图谱指南(MeNu GUIDE)——一种用于揭示与疾病病因相互作用的代谢物营养图谱 Wuerf, V. PDF N/A MeNu GUIDE - a metabolite nutrition graph to uncover interactions with disease etiology
sv-channels:使用一维卷积神经网络过滤基因组删除 Santuari, L. PDF N/A sv-channels: filtering genomic deletions using one-dimensional convolutional neural networks
节奏与背景(RnB):睡眠记录的光谱分析 Dube, J. PDF N/A Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings
利用语言引导的视觉模型进行空间蛋白质组学的广义细胞表型分析 Wang, X. PDF N/A Generalized cell phenotyping for spatial proteomics with language-informed vision models
较长的内含子往往含有更多的串联重复序列,并且更频繁地经历插入和删除,这些插入和删除大多发生在编码蛋白质的内在无序区域。 Homma, K. PDF N/A Longer internal exons tend to have more tandem repeats and more frequently experience insertions and deletions that are mostly in intrinsically disordered regions of the encoded proteins
长期服用裸盖菇素对前额-纹状体-丘脑回路动态性和有效性连接的影响 Pasquini, L. PDF N/A Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits
减少功能缺陷的老化造血干细胞(HSCs)可减轻老年受体小鼠的衰老相关表型 Wang, Y. PDF N/A Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice
从人类诱导多能干细胞(iPSCs)生成形态上不同的星形胶质细胞亚型揭示了胶质形态、功能和反应性之间的联系 O'Toole, K. PDF N/A Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity
核糖体丰度而非同源基因组成对于生殖系发育至关重要 Grobicki, K. Z. A. PDF N/A Ribosome abundance, not paralogue composition, is essential for germline development
CPSM:用于预测单个癌症患者生存概率的自动化机器学习管道R包 Kaur, H. PDF N/A CPSM: R-package of an Automated Machine Learning Pipeline for Predicting the Survival Probability of Single Cancer Patient
上游开放阅读框在果蝇进化和发育过程中缓冲翻译变异性 Sun, Y. PDF N/A Upstream open reading frames buffer translational variability during Drosophila evolution and development
AlphaRING: 通过蛋白质建模和残基相互作用网络分析进行错义变异分类 Logsdon, A. PDF N/A AlphaRING: Missense Variant Classification via Protein Modelling and Residue Interaction Network Analysis
首次为三种海葵(珊瑚纲:海葵目)宿主物种生成了从头组装的HiFi基因组 De Jode, A. PDF N/A The first de novo HiFi genome assemblies for three clownfish-hosting sea anemone species (Anthozoa: Actiniaria)
从Hi-C数据解读跨物种的3D基因组结构 Shkolikov, A. PDF N/A Deciphering the 3D genome organization across species from Hi-C data
雪貂乳腺内感染牛H5N1流感病毒导致哺乳期新生儿传播和死亡 Baker, P. H. PDF N/A Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission and mortality in suckling neonates
在肠道微生物群中,通过衣壳介导的大规模细菌基因组DNA的移动 Borodovich, T. PDF N/A Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
人类中枢神经系统中的体感高频振荡 Bailey, E. PDF N/A Somatosensory high frequency oscillations across the human central nervous system
很少是绝对的,总是高维的:神经代码如何随着皮层层次的变化而变化 Posani, L. PDF N/A Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy
产后中缝背侧核对脊髓内侧深背侧角RORβ中间神经元的5-羟色胺调节的成熟过程 West, C. W. PDF N/A Postnatal maturation of serotonergic modulation of spinal RORβ interneurons in the medial deep dorsal horn
揭示动态人脑相位一致性网络 Olsen, A. S. PDF N/A Uncovering dynamic human brain phase coherence networks
一种基于视紫红质的新型电压指示剂,用于在体内同时进行双光子光学记录与GCaMP Villette, V. PDF N/A A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo
Gria3突变小鼠(一种精神分裂症的遗传动物模型)中脑区特异性改变及活动调节基因的失调 Huang, W.-C. PDF N/A Brain-region-specific changes and dysregulation of activity regulated genes in Gria3 mutant mice, a genetic animal model of schizophrenia
终纹床核的促肾上腺皮质激素释放因子神经元在性别和动情周期阶段上表现出依赖性的突触活动差异,以及在焦虑增强的惊跳反应中的作用差异。 Chudoba, R. PDF N/A Corticotropin-releasing factor neurons of the bed nucleus of the stria terminalis demonstrate sex- and estrous phase-dependent differences in synaptic activity and in their role in anxiety-potentiated startle
淀粉样β寡聚体引起的社交和情境记忆障碍通过Sigma-1受体激活得以恢复 Djebari, S. PDF N/A Social and Contextual Memory Impairments Induced by Amyloid-β Oligomers are Rescued by Sigma-1 Receptor Activation
单个神经元对特定模态和非模态语言的处理 Yair, L. PDF N/A Modality-Specific and Amodal Language Processing by Single Neurons
激活下丘脑-脑桥-脊髓通路促进小鼠脊髓损伤后的运动启动和功能恢复 Li, Y. PDF N/A Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice
外侧下丘脑中的皮层输入整合主要由内侧前额叶皮层主导。 Razenberg, L. J. A. M. PDF N/A Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex
时钟基因period和timeless控制果蝇运动终末的突触发生 Ferreiro, M. J. PDF N/A Clock genes period and timeless control synaptogenesis in Drosophila motor terminals
在人类真菌病原体的形态发生过程中,细胞质的动态流动性 Serrano, A. PDF N/A Dynamic cytoplasmic fluidity during morphogenesis in a human fungal pathogen
使用无基因模型对发育细胞命运转变进行定量引导 Hajji, I. PDF N/A Quantitative guiding of developmental cell fate transitions using gene-free modelling
早期运动干扰了斑马鱼鳍再生过程中促进修复的细胞外基质程序 Lewis, V. M. PDF N/A Early exercise disrupts a pro-repair extracellular matrix program during zebrafish fin regeneration
人类滋养层干细胞和胎盘中的染色体不稳定性 Wang, D. PDF N/A Chromosomal Instability in Human Trophoblast Stem Cells and Placentas
在一种模型刺胞动物-藻类共生关系中,若缺乏异养性摄食,无性后代发育过程中共生关系会瓦解。 Bedgood, S. A. PDF N/A Symbiosis collapses during development of asexual offspring in the absence of heterotrophic feeding in a model cnidarian-algal symbiosis
通过四种方案在类器官中重建人类脑细胞多样性 Naas, J. PDF N/A Reconstitution of Human Brain Cell Diversity in Organoids via Four Protocols
无偏倚的多能性景观分析揭示了克隆命运偏倚的空间调节因子 Erickson, A. G. PDF N/A Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases
无偏倚的多能性景观分析揭示了克隆命运偏倚的空间调节因子 Erickson, A. G. PDF N/A Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases
全脑因果连接在解码神经反馈中的作用:一项元研究 Arab, F. PDF N/A Whole-brain causal connectivity during decoded neurofeedback: a meta study
使用可穿戴设备信号的婴幼儿自动持续注意力预测方法,尽快完成翻译。 Zhang, Y. PDF N/A ASAP: An automatic sustained attention prediction method for infants and toddlers using wearable device signals
结合神经绘画与转录组学揭示22q11.2缺失的细胞类型特异性形态和分子特征 Tegtmeyer, M. PDF N/A Combining NeuroPainting with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion
右侧后部θ波反映了在目标导向导航过程中,人类海马旁区因显著线索而发生的相位重置。 Güth, M. R. PDF N/A Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
热休克因子1调控跨物种的睡眠-觉醒周期 Yamazaki, S. PDF N/A Heat Shock Factor 1 Governs Sleep-Wake Cycles Across Species
在PS19小鼠中上调ANKHD1表达可减少Tau蛋白磷酸化,并缓解Tau毒性引起的认知功能障碍。 Tian, X. PDF N/A Upregulating ANKHD1 in PS19 mice reduces Tau phosphorylation and mitigates Tau-toxicity-induced cognitive deficits
无意识和有意识视觉处理的神经相关性 Menetrey, M. Q. PDF N/A Neural correlates of unconscious and conscious visual processing
小脑白质发育受依赖于fractalkine的小胶质细胞对少突胶质前体细胞的吞噬作用调控。 Chappell, M. K. PDF N/A Cerebellar white matter development is regulated by fractalkine-dependent microglia phagocytosis of oligodendrocyte progenitor cells
可以高效地从牛胚胎发育的不同阶段获得原始牛胚胎干细胞系,并且这些细胞系具有相似的分子特征。 Guiltinan, C. PDF N/A Primed bovine embryonic stem cell lines can be derived at diverse stages of blastocyst development with similar efficiency and molecular characteristics
保守的蚜虫唾液化学感觉蛋白效应子Mp10通过靶向植物细胞膜上的AMSH去泛素化酶来抑制模式触发的免疫 Gravino, M. PDF N/A The conserved aphid saliva chemosensory protein effector Mp10 targets plant AMSH deubiquitinases at cellular membranes to suppress pattern-triggered immunity
TaMYB7-A1的自然变异调控小麦对PHS的抗性并特化其地理适应性 Wang, H. PDF N/A Natural variations of TaMYB7-A1 regulate PHS resistance and specify wheat geographic adaptation
增强型肠道上皮共培养模型与轨道机械刺激:在食品纳米毒理学中的概念验证应用 Santoni, M. PDF N/A Enhanced Intestinal Epithelial Co-Culture Model with Orbital Mechanical Stimulation: A Proof-of-Concept Application in Food Nanotoxicology
比较功能性磁共振成像揭示了狗和人类在视觉皮层功能组织上对于生命感知存在的差异 Farkas, E. B. PDF N/A Comparative fMRI reveals differences in the functional organization of the visual cortex for animacy perception in dogs and humans
转译抑制剂与铜离子协同作用,增强抗生素活性 Vazquez-Hernandez, M. PDF N/A Trans-Translation inhibitors and copper ions synergize for enhanced antibiotic activity
糖磷酸介导的肽聚糖前体合成抑制 Keller, M. R. PDF N/A Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis
用于开发靶向IPNv VP2蛋白纳米抗体的小说库组装技术 Pino-Belmar, C. PDF N/A Novel Library Assembly Technique for Developing Nanobodies Targeting IPNv VP2 Protein
SAM转甲基化途径和腺苷再循环生成ATP对于系统性调节和免疫反应至关重要。 Nedbalova, P. PDF N/A SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response
温度和溶解有机物塑造了亚北极海中海洋原核生物的活动和基因表达 Amnebrink, D. PDF N/A Temperature and dissolved organic matter shape marine prokaryotic activity and gene expression in a sub-arctic sea
AACDB:抗原-抗体复合物数据库——一个全面的数据库,揭示相互作用界面的洞察力 Zhou, Y. PDF N/A AACDB: Antigen-Antibody Complex Database -- a Comprehensive Database Unlocking Insights into Interaction Interface
视觉训练诱导的人类枕叶快速睡眠纺锤体聚集现象通过全夜高清脑电图记录揭示 Gervan, P. PDF N/A Visual training induced occipital fast sleep spindle clustering in humans revealed by full-night HD-EEG recordings
通过昼夜节律转录因子NPAS2调节雄性和雌性小鼠中的芬太尼奖赏机制 Barko, K. PDF N/A Regulation of Fentanyl Reward in Male and Female Mice by the Circadian Transcription Factor NPAS2
任务期间个体大脑活动模式由不同的静息态网络预测,这些网络可能反映了局部神经生物学特征。 Scholz, R. PDF N/A Individual brain activity patterns during task are predicted by distinct resting-state networks that may reflect local neurobiological features
前运动核HVC中神经活动的时间和刻板序列传播的生物物理网络建模 Diab, Z. B. PDF N/A Biophysical network modeling of temporal and stereotyped sequence propagation of neural activity in the premotor nucleus HVC
AcrVIB1通过促进无功能的crRNA结合,使其易受RNase攻击,从而抑制CRISPR-Cas13b免疫。 Wandera, K. G. PDF N/A AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack
快速行进至分支形态 Kriuchechnikova, A. N. PDF N/A Fast marching to branching morphologies
CB1和CB2受体在调节母体免疫激活和围产期大麻素暴露对认知影响的方面表现出差异性作用。 Mackie, K. PDF N/A CB1 and CB2 receptors differentially modulate the cognitive impact of maternal immune activation and perinatal cannabinoid exposure
连接图谱和基于扰动的敏感性分析识别出MEK抑制剂作为人类肺成纤维细胞中的衰老抑制剂 Nayeri Rad, A. PDF N/A Connectivity Map and perturbation-based sensitivity analysis identifies MEK inhibitors as senolytics in human lung fibroblasts
尖生长细胞的形态动力学 Jones, G. W. PDF N/A Morphodynamics of tip growing cells
热激触发的小孢子转录重编程破坏了甘蓝型油菜花粉发育进程 Lohani, N. PDF N/A Heat-Triggered Transcriptional Reprogramming in Microspores Disrupts Progression of Pollen Development in Brassica napus L.
靶向DNA ADP-核糖基化在细菌中触发模板修复,在真核生物中引发碱基突变 Patinios, C. PDF N/A Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes
荧光假单胞菌中遗传电路的动力学 Rico, J. PDF N/A Dynamics of genetic circuits in Pseudomonas protegens
谷氨酸受体依赖的海马神经元细胞质酸化涉及从细胞外空间被动流入的质子。 Pedersen, S. E. PDF N/A Glutamate receptor-dependent cytosolic acidification in hippocampal neurons involves passive flux of protons from the extracellular space
干扰素Epsilon通过自分泌的细胞内信号传导保护上皮屏障免受病毒感染 Casazza, R. L. PDF N/A Interferon Epsilon Protects Epithelial Barriers from Viral Infection through Autocrine Intracellular Signaling
鉴定调控食道过敏性炎症的神经免疫回路 Kellerman, K. PDF N/A Identification of a Neuroimmune Circuit that Regulates Allergic Inflammation in the Esophagus
IL-33通过恢复体液免疫来预防复发性艰难梭菌感染。 naz, f. PDF N/A IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity
通过成像质谱流式细胞术对细胞外基质进行表型分析,确定了与过敏性气道炎症相关的不同细胞外基质环境。 Parkinson, J. E. PDF N/A Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation.
一种伴有婴儿肠结肠炎的自发性炎症动物模型 Kang, Z. PDF N/A An animal model for autoinflammation with infantile enterocolitis
鼻病毒作为严重哮喘儿童气道T细胞动态的驱动因素 Bryant, N. PDF N/A Rhinovirus as a Driver of Airway T-Cell Dynamics in Children with Severe Asthma
肠道细菌Bacteroidales的适应性变化有助于其与溶菌性噬菌体的稳定共存。 Cortes-Martin, A. PDF N/A Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages
尼日利亚夸拉州伊洛林大都会区养殖鱼类中迟缓爱德华菌的抗菌敏感性特征 OLABISI, F. O. PDF N/A ANTIMICROBIAL SUSCEPTIBILITY PROFILE OF Edwardsiella tarda FROM FARMED FISH IN ILORIN METROPOLIS, KWARA STATE NIGERIA
有益细菌枯草芽孢杆菌(B. subtilis)的生物膜和浮游细胞在应对原生动物捕食者痢疾内变形虫(Entamoeba histolytica)时采用的不同应对策略。 Kolodkin-Gal, I. PDF N/A Differential coping strategies exerted by biofilm and planktonic cells of the beneficial bacterium B. subtilis in response to the protozoan predator Entamoeba histolytica.
博茨瓦纳、加蓬、肯尼亚、南非和美国非洲象体内潜伏的象内皮嗜性疱疹病毒和象伽玛疱疹病毒感染情况 Pearson, V. R. PDF N/A Quiescent Infections of Elephant Endotheliotropic Herpesviruses and Elephant Gammaherpesviruses in African Elephants in Botswana, Gabon, Kenya, South Africa and USA
猎物移动影响虚拟二营养级系统中捕食者专业技能的获取 Fraser Franco, M. PDF N/A Prey movement shapes the acquisition of predator expertise in a virtual bi-trophic system
在具有角色间速率变化的Mkv模型上 Capobianco, A. PDF N/A On the Mkv Model with Among-Character Rate Variation
尼莫知道:小丑鱼能够区分细小和广阔地理尺度上的隐秘宿主物种,并揭示了小丑鱼与其宿主海葵之间潜在的适应性辐射。 Chiodo, T. PDF N/A Nemo knows: clownfishes differentiate cryptic host species across fine and broad geographic scales and reveal a potential adaptive radiation in the clownfish-hosting sea anemones.
非洲无花果蝇(Zaprionus indianus)在温带地区定居后翅膀尺寸的快速进化 Gray, W. J. PDF N/A Rapid wing size evolution in African fig flies (Zaprionus indianus) following temperate colonization
HSP90 缓冲了 BRCA1 中的有害遗传变异 Gracia, B. PDF N/A HSP90 buffers deleterious genetic variations in BRCA1
GWAC:一种在数据受限物种中识别功能变异的机器学习方法 Sharo, A. G. PDF N/A GWAC: A machine learning method to identify functional variants in data-constrained species
用于多组学分析样品制备的单个微流控装置 Ravi Kumar, R. K. PDF N/A A single microfluidic device for multi-omics analysis sample preparation
在微流控人体皮肤等效物中以单细胞分辨率复制动态免疫反应 Hindle, S. A. PDF N/A Replicating dynamic immune responses at single-cell resolution within a microfluidic human skin equivalent
基于结构的模拟的前瞻性评估揭示了其预测激酶突变对抑制剂结合影响的能力 Singh, S. PDF N/A Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding
OncotreeVIS - 一种用于可视化突变树队列的交互式图形用户界面 Baciu-Dragan, M. A. PDF N/A OncotreeVIS - an interactive graphical user interface for visualizing mutation tree cohorts
靶向TEAD的小分子通过诱导辅因子转换来调节Hippo通路 Guarnaccia, A. D. PDF N/A TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway
单细胞分辨率的空间分析:抗原呈递型癌症相关成纤维细胞微环境的解析 Chen, X. PDF N/A Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches
鉴定MRTFA/SRF通路作为癌症中静止状态的关键调节因子。 Panesso-Gomez, S. PDF N/A Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer.
池塘和池塘养殖的吉富罗非鱼微生物组动态 Delamare-Deboutteville, J. PDF N/A Microbiome Dynamics in Tank- and Pond-Reared GIFT Tilapia
染色体工程恢复含有复杂染色体8重排的细胞的整倍性 Lee, S. N. PDF N/A Chromosome engineering to restore euploidy in cells harboring a complex rearrangement of chromosome 8
西部斜坡割喉鳟(Oncorhynchus lewisi)的基因组组装揭示了其与虹鳟之间存在种间染色体重排。 Flores, A.-M. PDF N/A The genome assembly of the westslope cutthroat trout, Oncorhynchus lewisi, reveals interspecific chromosomal rearrangements with the rainbow trout
PanTax:利用泛基因组图谱对宏基因组数据进行菌株水平分类 Zhang, W. PDF N/A PanTax: Strain-level taxonomic classification of metagenomic data using pangenome graphs
CellPatch:一种高效的基础模型,用于单细胞转录组学,采用启发式补丁方法 Wu, H.-J. PDF N/A CellPatch: a Highly Efficient Foundation Model for Single-Cell Transcriptomics with Heuristic Patching
滤泡性淋巴瘤和慢性淋巴细胞白血病在单细胞分辨率下的增殖微环境 Ferreira, A. P. PDF N/A The follicular lymphoma and chronic lymphocytic leukemia proliferative microenvironment at single-cell resolution
跨组织图注意力网络用于半监督基因表达预测 Wang, S. PDF N/A Cross-tissue Graph Attention Networks for Semi-supervised Gene Expression Prediction
基于神经形态成像的人血细胞计数法 Zhang, Z. PDF N/A Neuromorphic Imaging Cytometry on Human Blood Cells

medRxiv

标题 作者 PDF链接 代码仓库 Title
了解心内膜心电图成像在三维再入环路心外膜-心内膜标测中的应用 Toloubidokhti, M. PDF N/A Understanding the Utility of Endocardial Electrocardiographic Imaging in Epi-Endocardial Mapping of 3D Reentrant Circuits
为什么美利坚合众国没有批准《联合国儿童权利公约》?作为新的卫生政策分析框架的否决支点 Harris, L. PDF N/A Why has the United States of America not Ratified the United Nations Convention on the Rights of the Child? The veto fulcrum as a new health policy analysis framework
重新分析APOL1肾脏数据支持新的“种族”伦理 Burke, C. O. PDF N/A Re-analyzed APOL1 kidney data support new ethics of 'race'
评估新型冠状病毒肺炎(COVID-19)对拉各斯州社区药房服务交付的影响 Ajibola, O. G. PDF N/A An Assessment of the Effects of Coronavirus Disease 2019 (COVID-19) on Community Pharmacy Service Delivery in Lagos State
生物银行规模的阿尔茨海默病及相关痴呆症特征研究揭示了潜在的致病变异、风险因素及跨不同祖先的遗传修饰因子。 Khani, M. PDF N/A Biobank-scale characterization of Alzheimer's disease and related dementias identifies potential disease-causing variants, risk factors, and genetic modifiers across diverse ancestries
脊髓性肌萎缩基因治疗早期安全概况:病例系列分析 Spellman, R. G. PDF N/A Early Life Safety Profiling of Gene Therapy for Spinal Muscular Atrophy: A Case Series Analysis
煤火相关PM2.5暴露引起的癌症发病率的后续研究。 Nayagam, S. N. PDF N/A Follow-up of cancer incidence associated with smoke-related PM2.5 exposure due to a coal mine fire.
揭示因果基因-组织对和变异体:一种控制微小效应的多变量TWAS方法 Yang, Y. PDF N/A Uncovering causal gene-tissue pairs and variants: A multivariable TWAS method controlling for infinitesimal effects
一项试点前后试验,有无补贴以促进孟加拉国农村地区安全后院家禽养殖实践,预防接触家禽及家禽粪便。 Kwong, L. H. PDF N/A A pilot pre-post trial with and without subsidy to promote safe backyard poultry-raising practices to prevent exposure to poultry and poultry feces in rural Bangladesh
C2人背根神经节中IGHG4的表达可能将B细胞与扩散性慢性颈部疼痛联系起来 Mancilla Moreno, M. PDF N/A IGHG4 Expression in C2 Human Dorsal Root Ganglion Potentially Links B Cells to Spreading Chronic Neck Pain
多队列循环蛋白质组对主动脉瘤风险的因果效应:一项孟德尔随机化研究 Zheng, Y. PDF N/A Causal Effect of Multi-cohort Circulating Proteome on the Risk of Aortic Aneurysm: A Mendelian Randomization Study