| 已撤回：成年小鼠齿状回苔藓细胞对颗粒细胞和CA3区的兴奋性影响：体外和体内研究。 |
Bernstein, H. L. |
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N/A |
WITHDRAWN: Excitatory effects of dentate gyrus mossy cells on granule cells and area CA3: an vitro and in vivo study in adult mice. |
| 基于HHpred方法对SARS-CoV-2蛋白质进行重新注释，为更深入理解该病毒开启了新的机遇 |
Brezellec, P. |
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N/A |
Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus |
| 在小鼠决策过程中，先验信息的全脑表征 |
Findling, C. |
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N/A |
Brain-wide representations of prior information in mouse decision-making |
| 杜兴肌营养不良症（Duchenne Muscular Dystrophy）中成纤维细胞的包含导致疾病加重，MYOrganoids揭示了微肌营养不良蛋白治疗效力的局限性 |
Palmieri, L. |
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Disease exacerbation by fibroblast inclusion in Duchenne Muscular Dystrophy MYOrganoids reveals limitations of microdystrophin therapeutic efficacy |
| 从孵化场到远洋：气候变化与鲑鱼海洋生存的关联 |
Kitada, S. |
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N/A |
Hatcheries to high seas: climate change connections to salmon marine survival |
| scELMo：来自语言模型的嵌入在单细胞数据分析中是优秀的学习者 |
Liu, T. |
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scELMo: Embeddings from Language Models are Good Learners for Single-cell Data Analysis |
| 可3D打印的非侵入性非人灵长类动物头部固定系统 |
Shahbazi, E. |
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N/A |
3D-Printable Non-invasive Head Immobilization System for Non-Human Primates |
| 撤回：人类胎盘中截短的NLRC5异构体：表达、由miR-218-5p调控及其在滋养层细胞中的功能 |
Shan, Y. |
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N/A |
WITHDRAWN: Truncated NLRC5 isoforms in human placenta: expression, regulation by miR-218-5p, and function in trophoblasts |
| 记忆元认知成分由楔前叶与海马之间高伽马活动所支持的结构构成 |
Pan, K. |
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N/A |
Components of Mnemonic Metacognition Constitutionally Supported by High Gamma Activity Between the Precuneus and Hippocampus |
| 两亲螺旋8的膜曲率关联驱动组成型GPCR内吞作用 |
Herlo, R. |
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Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis |
| 超越皮层几何：罕见的长程连接塑造的大脑动力学 |
Vohryzek, J. |
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Beyond cortical geometry: brain dynamics shaped by rare long-range connections |
| 人CD29+/CD56+肌源性前体细胞展现出向腱细胞分化的潜力，并能促进肌腱的再生。 |
Shao, X. |
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Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration |
| 肉食性动物的适应性景观揭示了头骨、附肢骨骼和轴向骨骼之间的功能权衡。 |
Law, C. |
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N/A |
The carnivoran adaptive landscape reveals functional trade-offs among the skull, appendicular, and axial skeleton |
| 一种新型进食机制：太阳鸟通过舌内吸力饮用花蜜 |
Cuban, D. |
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N/A |
A novel feeding mechanism: Sunbirds drink nectar via intralingual suction |
| 药物激活整合应激反应激酶抑制病理性线粒体碎片化 |
Baron, K. R. |
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Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation |
| 发现猴痘病毒H3中的硫酸乙酰肝素结合域作为抗痘病毒药物靶点：结合AI与MD模拟 |
Zheng, B. |
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N/A |
Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combining AI and MD Simulations |
| BiRNA-BERT通过自适应分词实现了高效的RNA语言建模 |
Tahmid, M. T. |
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BiRNA-BERT Allows Efficient RNA Language Modeling with Adaptive Tokenization |
| 基于接触的胸苷酸转移促进集体肿瘤生长 |
Siddiqui, M. A. |
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N/A |
Contact-based thymidylate transfer promotes collective tumor growth |
| 拟南芥中亲本冲突对印记基因的影响。 |
Le veve, A. |
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N/A |
The effect of parental conflict in imprinting genes in A. lyrata. |
| 南方海獭（Enhydra lutris nereis）的理论咬合力和颌肌生长模式 |
Law, C. |
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N/A |
Growth patterns of theoretical bite force and jaw musculature in southern sea otters (Enhydra lutris nereis) |
| 河流无脊椎动物在景观中表现出时间生态过程的空间不对称性 |
Lin, X. |
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Riverine Invertebrates Exhibit Spatial Asymmetry in Temporal Ecological Processes Across Landscapes |
| SbcB 以不依赖核酸外切酶的方式促进霍乱弧菌的自然转化过程。 |
Dalia, T. N. |
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N/A |
SbcB facilitates natural transformation in Vibrio cholerae in an exonuclease-independent manner |
| 通过流形再现分析进行生成模型验证 |
Lazzaro, N. |
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N/A |
Generative Models Validation via Manifold Recapitulation Analysis |
| 西澳大利亚城市灌木丛火灾后的兰花输家和赢家：与其他特征深度融合的响应连续体 |
Brundrett, M. C. |
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Orchid losers and winners after fire in West Australian urban bushland: A response continuum deeply integrated with other traits |
| TFAP2C是调节子宫内滋养层细胞侵袭和深部血绒毛膜胎盘形成的关键因子。 |
Dominguez, E. M. |
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TFAP2C is a key regulator of intrauterine trophoblast cell invasion and deep hemochorial placentation |
| PPD-H1通过提高抗逆性和能量代谢，在高温环境下增强花粉活力 |
Lan, T. |
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PPD-H1 Improves Stress Resistance and Energy Metabolism to Boost Spike Fertility under High Ambient Temperatures |
| 利用CryFold改进冷冻电镜图的自动模型构建 |
Su, B. |
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N/A |
Improved automated model building for cryo-EM maps using CryFold |
| 来自L. meyenii Walp的脂质纳米颗粒通过多模态蛋白质冠形成减轻脓毒症 |
Sung, J. J. |
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Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation |
| 性特异性调控芬太尼奖赏的昼夜节律转录因子NPAS2 |
Barko, K. |
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Sex-specific Regulation of Fentanyl Reward by the Circadian Transcription Factor NPAS2 |
| 基于神经形态成像的人类血细胞计数 |
Zhang, Z. |
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N/A |
Neuromorphic Imaging Cytometry on Human Blood Cells |
| NOTCH3激活机制的异质性揭示了针对CADASIL的靶向治疗潜力。 |
Hosseini-Alghaderi, S. S. |
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N/A |
Heterogeneity of NOTCH3 activation mechanisms uncovers therapeutic potential for targeted therapies for CADASIL. |
| 在早衰小鼠中，TFAM和线粒体DNA拷贝数操作引发的组织特异性反应 |
Kremer, L. S. |
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Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice |
| 多功能便携式Cas12a介导的抗生素抗性标记检测 |
Vargas-Reyes, M. |
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N/A |
Versatile and Portable Cas12a-mediated Detection of Antibiotic Resistance Markers |
| 高分辨率冷冻电镜展示了肠产毒性大肠杆菌中的I型和IV型菌毛结构的水合形态。 |
Nakamura, S. |
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N/A |
High-resolution Cryo-EM visualises hydrated type I and IV pilus structures from enterotoxigenic Escherichia coli |
| 线粒体调控巨核细胞-红细胞祖细胞的细胞命运决定 |
Sung, E. |
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N/A |
Mitochondria Regulate the Cell Fate Decisions of Megakaryocyte-Erythroid Progenitors |
| 成熟皮下脂肪细胞中的Wnt激活通过依赖于ATGL的脂解作用导致脂肪营养不良和皮肤纤维化。 |
Ma, Q. |
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Wnt activation in mature dermal adipocytes leads to lipodystrophy and skin fibrosis via ATGL-dependent lipolysis. |
| 全球高致病性禽流感H5N1和H5Nx的风险地图：基于2020年以来发生的疫情事件 |
Dupas, M.-C. |
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N/A |
Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onward |
| 自动发现最优离散字符模型 |
Boyko, J. |
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N/A |
Automatic Discovery of Optimal Discrete Character Models |
| 一种与Haematomyzus elephantis共生的专性共生体，其基因组显著减少，类似于吸血虱中的共生细菌。 |
Rihova, J. |
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N/A |
An obligate symbiont of Haematomyzus elephantis with a strongly reduced genome resembles symbiotic bacteria in sucking lice |
| 新型增殖相关基因标志物在微卫星稳定型结直肠癌预后中的开发与验证 |
Wang, S. |
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N/A |
Development and validation of novel proliferation-related gene signature for MSS colorectal cancer prognosis |
| 自上而下的形状线索对半透明感知的影响 |
Nagai, T. |
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N/A |
Top-Down Effects on Translucency Perception in Relation to Shape Cues |
| 朊病毒安全实验室拭子测试 |
Simmons, S. M. |
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N/A |
Prion safety laboratory swipe test |
| 慢性鼻-鼻窦炎伴鼻息肉与不伴鼻息肉基因表达的比较 |
Kasem, M. |
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N/A |
Comparison of Gene Expression between Chronic Rhinosinusitis with Nasal Polyposis and without Nasal Polyposis |
| 特米尼洛山雪中的微塑料（意大利列蒂） |
Pietrelli, L. |
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N/A |
MICROPLASTICS IN THE MOUNT TERMINILLO SNOW (RIETI, ITALY) |
| 预测与心肌梗塞和肺癌相关的双向分子预后特征：一种计算机模拟视角 |
Nandi, D. D. |
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N/A |
Predicting Prognostic Bidirectional Molecular Signatures Associating Myocardial Infarction and Lung Cancer: An In-Silico Perspective |
| 中性粒细胞胞外陷阱基因表达特征可识别胰腺肿瘤转移抑制的预后和可靶向信号轴 |
McDonald, P. C. |
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N/A |
Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours |
| 单细胞表观遗传分析揭示了与肾癌中BAP1缺陷相关的干扰素应答高水平程序 |
Camp, S. Y. |
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N/A |
Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer |
| 比较儿童数学能力和流利度的神经认知机制：来自fNIRS研究的见解 |
Yeo, A. Y. N. |
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N/A |
Comparing neurocognitive mechanisms of mathematical ability and fluency in children: insights from an fNIRS study |
| 时间对感觉运动适应中的一个耗时、灵活的成分和一个快速、不灵活的成分产生影响。 |
Leow, L.-A. |
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N/A |
Time affects a time-consuming, flexible component and a fast, inflexible component of sensorimotor adaptation. |
| 蝙蝠的自组织声学行为源于简单的规则。 |
Hase, K. |
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N/A |
Self-organized acoustic behavior in bats arises from simple rules |
| 男性创业公司创始人的年龄标准化睾酮水平在B轮融资时达到峰值 |
Moradian, J. |
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N/A |
Age-Normalized Testosterone Peaks at Series B for Male Startup Founders |
| 生物催化领域的语言模型助手 |
Nana Teukam, Y. G. |
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N/A |
A language model assistant for biocatalysis |
| 癌基因诱导的衰老和衰老相关分泌表型（SASP）决定了帕博西尼在PIK3CA突变型结直肠癌中的疗效。 |
Cao, P. |
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N/A |
Oncogene-induced senescence and senescence-associated secretory phenotype (SASP) determine the efficacy of palbociclib in PIK3CA mutated colorectal cancer |
| 沿着一条欧洲小河进行的AI辅助慢性混合风险评估揭示了多个存在风险的地点，而药物是主要的驱动因素。 |
Weichert, F. G. |
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N/A |
AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers |
| 标准流靶向蛋白质组学用于硫代葡萄糖苷生物合成途径中酶的定量 |
Vik, D. |
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N/A |
Standard-flow targeted proteomics for quantification of enzymes in glucosinolate biosynthetic pathways |
| 网格到位置细胞连接性在十一个不同房间中的表现 |
Aggarwal, A. |
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N/A |
Grid to Place Cell Connectivity in Eleven Different Rooms |
| 空气-液体界面精密切割肺切片（PCLS-ALI）：一种用于研究肺曲霉病的新型体外模型 |
Gonzales-Huerta, L. E. |
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N/A |
Precision-cut lung slices in air-liquid interface (PCLS-ALI): A novel ex-vivo model for the study of Pulmonary Aspergillosis |
| 公平对待它：一种简单、快速且高效的方法，用于从死亡帽蘑菇（Amanita phalloides）中提取鹅膏毒素 |
Adams, C. A. |
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N/A |
Giving it a fair shake: A simple, fast, & efficient method to extract amatoxins from the death cap mushroom, Amanita phalloides |
| 长期平衡选择维持了青蛙的隐秘颜色多态性 |
Goutte, S. |
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N/A |
Long-term balancing selection maintains cryptic color polymorphism in frogs |
| 放射疗法在血液恶性肿瘤中的诱变影响和进化作用 |
Diamond, B. |
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N/A |
Mutagenic impact and evolutionary influence of radiotherapy in hematologic malignancies |
| 通过FDR控制肽身份传播，提高差异丰度蛋白质的检测能力 |
Solivais, A. J. |
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N/A |
Improved detection of differentially abundant proteins through FDR-control of peptide-identity-propagation |
| 静脉基因治疗可改善猫桑德霍夫病的寿命和临床结果 |
Maguire, A. S. |
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N/A |
Intravenous gene therapy improves lifespan and clinical outcomes in feline Sandhoff Disease |
| 阿尔茨海默病中溶酶体酶基因的不足 |
Benitez, B. A. |
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N/A |
Haploinsufficiency of lysosomal enzyme genes in Alzheimers disease |
| 标准学习与反馈延迟：来自计算模型和行为实验的见解 |
Crossley, M. J. |
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N/A |
Criterial Learning and Feedback Delay: Insights from Computational Models and Behavioral Experiments |
| VNC-Dist：一种基于机器学习的工具，用于量化秀丽隐杆线虫腹神经索中神经元的位置 |
Saharkhiz, S. |
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N/A |
VNC-Dist: A machine learning-based tool for quantification of neuronal positioning in the ventral nerve cord of C. elegans |
| 评估无序区域边界处多聚XYs的螺旋稳定性与MD模拟 |
Goncalves-Kulik, M. |
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N/A |
Assessing the helical stability of polyXYs at the boundaries of Intrinsically Disordered Regions with MD simulations |
| 电场耦合使得动作电位的传导成为可能。 |
Waaben, J. |
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N/A |
Ephaptic coupling enables action potential conduction |
| 胰岛素/胰岛素样生长因子信号通路促进果蝇雌性更高的脂肪储存 |
Biswas, P. |
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N/A |
Insulin/insulin-like growth factor signaling pathway promotes higher fat storage in Drosophila females |
| 内侧颞叶中空间和价值的分布式编码 |
Yang, L. |
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N/A |
Distributed coding of space and valence in the medial temporal lobe |
| 感觉历史驱动LP/丘脑枕-前额叶皮层电路中的适应性神经几何结构 |
Leow, Y. N. |
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N/A |
Sensory History Drives Adaptive Neural Geometry in LP/Pulvinar-Prefrontal Cortex Circuits |
| 通过优化嗅觉记忆网络中的神经流形进行表征学习 |
Hu, B. |
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N/A |
Representational learning by optimization of neural manifolds in an olfactory memory network |
| 体内类似的无支架三维体外肌肉萎缩模型：个性化医学中锚定细胞片工程的案例 |
Shahin-Shamsabadi, A. |
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N/A |
in vivo-like Scaffold-free 3D in vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine |
| 黑鸟：使用合成和低覆盖率长读取进行结构变异检测 |
Meleshko, D. |
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N/A |
Blackbird: structural variant detection using synthetic and low-coverage long-reads |
| 蛋白质晶体结构和AlphaFold预测模型的分子表面的几何特性 |
Wang, L. |
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N/A |
The geometric properties of the molecular surfaces of protein crystal structures and AlphaFold predicted models |
| 用于增强非编码RNA分类的核苷酸序列生成方法 |
Chiquitto, A. G. |
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N/A |
Generative Approaches for Nucleotide Sequences to Enhance Non-coding RNA Classification |
| 阐明非同义替代对人胰岛淀粉样多肽构象变化的影响 |
Bashar, M. A. |
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N/A |
Elucidating conformational alteration of human islet amyloid polypeptide by nonsynonymous substitution |
| 在二叠纪末大灭绝后，中国低纬度地区的河流生态系统迅速恢复 |
Guo, W. |
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N/A |
Rapid riparian ecosystem recovery in low-latitudinal North China following the end-Permian mass extinction |
| 综合心血管对分级下肢负压的剂量反应 |
Whittle, R. S. |
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N/A |
Integrative cardiovascular dose-response to graded lower body negative pressure |
| 时间与催产素在有无妊娠糖尿病的小鼠和人类中的疗效交互作用 |
Duong, T. V.-Q. |
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N/A |
Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes |
| 从神经元到网络的非线性脑连接：量化、来源与定位。 |
Raffaelli, G. T. |
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N/A |
Nonlinear brain connectivity from neurons to networks: quantification, sources and localization. |
| 预测在观看电影过程中由前额叶皮层fNIRS信号引起的全脑神经动力学 |
Gao, S. |
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N/A |
Predicting whole-brain neural dynamics from prefrontal cortex fNIRS signal during movie-watching |
| 抑制Notch信号通路可减轻癫痫持续状态诱导的青春期大鼠脑内癫痫放电 |
Yuan, P. |
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N/A |
Inhibition of Notch Signaling Attenuates Epileptic Discharges in the Adolescent Rat Brain after Status Epilepticus Induction |
| 脂滴蛋白Perilipin 2通过胰腺胰岛中的β细胞脂噬作用和胰高血糖素表达，对胰岛素分泌的调控至关重要。 |
Liu, S. |
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N/A |
Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets |
| 毛发再生新技术：含外泌体的不同商业产品比较 |
Ferrugia, G. |
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N/A |
New technologies for hair follicle growth and regeneration: comparison between different commercial products contain exosomes |
| Meioc-Piwil1复合物调控rRNA转录以促进精原干细胞的分化 |
Kawasaki, T. |
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N/A |
Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells |
| 利用基于视频的深度学习技术解析自然环境中的蜜蜂摇摆舞 |
Grison, S. |
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N/A |
Unraveling Honey Bee's Waggle Dances in Natural Conditions with Video-Based Deep Learning |
| 湿地草甸中刈割与覆盖对蜗牛群落影响的实验比较 |
Farkas, R. |
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N/A |
Experimental comparison of mowing and mulching on snail communities in wet meadows |
| 将性染色体系统与四足动物成年性别比例变化联系起来的群体统计学途径 |
Pipoly, I. |
PDF |
N/A |
Demographic pathways linking sex-chromosome system to adult sex ratio variation across tetrapods |
| 幼体营养不良下的扩散进化成本 |
Vibishan, B. |
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N/A |
Costs of dispersal evolution under larval malnutrition |
| 当性选择遇到遗传漂变：有限种群中雄性性状与雌性偏好的共同演化 |
Xu, K. |
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N/A |
When sexual selection meets genetic drift: the coevolution of male traits and female preferences in finite populations |
| 在安第斯山脉的拟似杂交区中，阿塔佩特斯刷嘴雀（雀形目，雀科）表现出表型变异和行为隔离的弱化。 |
Munoz-Quintana, G. |
PDF |
N/A |
Phenotypic variation and weak behavioral isolation in a putative hybrid zone between Andean Atlapetes brushfinches (Passerellidae) |
| 结合单核苷酸多态性（SNP）亲本单体型分析与强度分析，可识别出人类胚胎植入前期的减数分裂和有丝分裂非整倍体，以及频繁的片段非整倍体。 |
Handyside, A. H. |
PDF |
N/A |
Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos |
| 解析cfDNA片段化模式：将染色质结构与癌症诊断敏感性相联系 |
Johnston, A. D. |
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N/A |
Unraveling cfDNA Fragmentation Patterns: Linking Chromatin Architecture to Cancer Diagnostic Sensitivity |
| Ca2+/钙调蛋白依赖性蛋白激酶II的α和β亚型在哺乳动物睡眠中的参与有限 |
Yang, W. |
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N/A |
Limited involvement of Ca2+/calmodulin-dependent kinase II alpha and beta in mammalian sleep |
| 含有三核苷酸重复序列的DNA通过噬菌体T7的复制体进行复制 |
Lee, S.-J. |
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N/A |
Replication of DNA containing trinucleotide repeats by the bacteriophage T7 replisome |
| NK-92细胞对白色念珠菌的增强抗真菌活性通过甘露聚糖特异性嵌合抗原受体介导 |
Yamazaki de Campos, G. |
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N/A |
Enhanced antifungal activity of NK-92 cells against Candida albicans mediated by a mannan-specific chimeric antigen receptor |
| 使用生成模型进行概率性脑部MR图像变换 |
Rezvani, S. |
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N/A |
Probabilistic Brain MR Image Transformation Using Generative Models |
| 一种核酸前药能激活线粒体呼吸并延长寿命 |
Anada, T. |
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N/A |
A nucleic acid prodrug activates mitochondrial respiration and extends lifespan |
| 小尺寸植入式神经探针，配备高效倒装芯片微型LED，用于活体光遗传学研究 |
Abrantes, M. |
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N/A |
Small form factor implantable neural probe with efficient flip chip micro LED for in vivo optogenetics |
| 非人灵长类动物子宫各层在妊娠期间的时间依赖性材料特性和组成 |
Fodera, D. M. |
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N/A |
Time-Dependent Material Properties and Composition of the Nonhuman Primate Uterine Layers Through Gestation |
| 利用可解释的人工智能设计高效抗生物膜、抗菌肽 |
Pikalyova, K. |
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N/A |
Design of highly potent anti-biofilm, antimicrobial peptides using explainable artificial intelligence |
| 可解释的聚类性能指标 |
Mondal, K. |
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N/A |
Physically Interpretable Performance Metrics for Clustering |
| Squidiff：利用扩散模型预测细胞发育及对扰动的响应 |
He, S. |
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N/A |
Squidiff: Predicting cellular development and responses to perturbations using a diffusion model |
| Clair3-RNA：一种基于深度学习的用于长读长RNA测序数据的小变异检测工具 |
Zheng, Z. |
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N/A |
Clair3-RNA: A deep learning-based small variant caller for long-read RNA sequencing data |
| AlphaFold 对整个基因组的预测概览 |
Cazals, F. |
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N/A |
AlphaFold predictions on whole genomes at a glance |
| 使用综合生物信息学方法鉴定结直肠癌中的潜在枢纽基因和治疗靶点 |
D, K. |
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N/A |
Identification of Potential Hub Genes and Therapeutic Targets in Colorectal Cancer Using Integrated Bioinformatics Approaches |
| Pharming：从肿瘤单细胞DNA测序中联合克隆树重建SNV和CNA演化 |
Weber, L. L. |
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N/A |
Pharming: Joint Clonal Tree Reconstruction of SNV and CNAEvolution from Single-cell DNA Sequencing of Tumors |
| 基于深度学习的酶最适pH预测及通过点突变提高酸耐受性的设计 |
Qiu, S. |
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N/A |
Deep learning-based prediction of enzyme optimal pH and design of point mutations to improve acid resistance |
| 通过机器学习分析免疫单细胞RNA-seq数据，揭示预测检查点免疫治疗反应的基因和细胞特征 |
Pinhasi, A. |
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N/A |
Uncovering Predictive Gene and Cellular Signatures for Checkpoint Immunotherapy Response through Machine Learning Analysis of Immune Single-Cell RNA-seq Data |
| MAX2泛素连接酶-受体-底物复合体协同独脚金内酯感知机制 |
Arold, S. T. |
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N/A |
Mechanism of cooperative strigolactone perception by the MAX2 ubiquitin ligase-receptor-substrate complex |
| RNA动力学与相分离的中等分辨率模型，显式包含Mg²⁺ |
Li, S. |
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N/A |
An Intermediate Resolution Model of RNA Dynamics and Phase Separation with Explicit Mg2+ |
| 基因编码纳米颗粒的单颗粒追踪：优化表达以进行细胞质扩散研究 |
Korunova, E. |
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N/A |
Single Particle Tracking of Genetically Encoded Nanoparticles: Optimizing Expression for Cytoplasmic Diffusion Studies |
| RAS通路抑制剂与靶向药物的联合在多种癌症类型中具有致癌KRAS变异的源自患者的细胞球体中表现出活性。 |
Davoudi, Z. |
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N/A |
Combinations of RAS pathway inhibitors with targeted agents are active in spheroids of patient-derived cells with oncogenic KRAS variants from multiple cancer types |
| 工程化儿童肿瘤保留了患者肿瘤的基因型和表型，适用于精准医学。 |
Jung, M. |
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N/A |
Engineered paediatric tumours retain patient tumour genotype and phenotype for precision medicine. |
| 线粒体基因组编码的mitomiRs调控三阴性乳腺癌中的细胞可塑性和铁死亡敏感性 |
Kandettu, A. |
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N/A |
Mitochondrial genome-encoded mitomiRs regulate cellular plasticity and susceptibility to ferroptosis in triple-negative breast cancer |
| 通过提示语言模型实现多功能可控蛋白质生成 |
Wang, Z. |
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N/A |
Multi-purpose controllable protein generation via prompted language models |
| 高吞吐量蛋白质组学和磷酸蛋白质组学分析的福尔马林固定石蜡包埋组织 |
Haines, M. |
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N/A |
High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissue |
| 跨颈椎和腰椎脊髓的dI3神经元感觉运动回路图谱 |
Nasiri, S. |
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N/A |
Mapping of dI3 neuron sensorimotor circuits across the cervical and lumbar spinal cord |
| 增强电生理学研究中从场电位提取信息的能力 |
Akella, S. |
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N/A |
Enhancing information extraction from field potentials in electrophysiology studies |
| 同时失去CAMK2A和CAMK2B揭示了内源性体内底物 |
Rigter, P. M. F. |
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N/A |
Simultaneous loss of CAMK2A and CAMK2B reveals endogenous in vivo substrates |
| 受损的补体调节在肺移植后驱动慢性肺移植物功能障碍。 |
Kulkarni, H. S. |
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N/A |
Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation. |
| 孤立的小鼠成年心肌细胞表现出最低的线粒体ATP需求，并高度依赖糖酵解。 |
Mattam, U. |
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N/A |
Isolated Mouse Adult Cardiomyocytes Display Minimal Mitochondrial ATP Demand and Maximal Reliance on Glycolysis |
| PRDM16-CtBP1/2复合物与HDAC1/2相互作用，调节神经发生转录程序并指导皮层神经元迁移 |
Warren, S. |
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N/A |
A PRDM16-CtBP1/2 Complex Interacts with HDAC1/2 to Regulate Transcriptional Programs of Neurogenesis and Guide Cortical Neuron Migration |
| ILSM：用于分析三方交互网络互连结构的软件包 |
Sun, W. |
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N/A |
ILSM: A package for analyzing the interconnection structure of tripartite interaction networks |
| 在温度变化条件下果蝇发育时间的阶段特异性热塑性 |
Chattopadhyay, A. |
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N/A |
Thermal Plasticity of Stage Specific Development Time in Drosophila melanogaster under Shifting Temperatures |
| 推进远程与低资源医疗服务的进展：通过微生物活检皮肤样本在不同温度下对mRNA管家基因稳定性的分析 |
Falckenhayn, C. |
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N/A |
Advancing Remote and Low-Resource Healthcare Delivery with Microbiopsy Skin Sample mRNA Housekeeping Gene Stability Analysis Across Various Temperatures |
| 结合体细胞突变和基因表达的综合分析揭示了在DNA损伤应答下，牙龈颊癌中与核斑点相关的增强干细胞特性 |
Kumar, S. |
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N/A |
Combined analysis of somatic mutations and gene expression reveals nuclear speckles-associated enhanced stemness in gingivobuccal carcinoma under DNA damage response |
| 通过计算优化和结构工程显著提升接枝纳米抗体的抗病毒疗效 |
HUO, L. |
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N/A |
Significantly enhancing antiviral efficacy by computational optimization and structural engineering of grafted nanobodies |
| 质粒、前噬菌体和防御系统从植物微生物群基因组中被耗尽 |
Bograd, A. |
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N/A |
Plasmids, Prophages and Defense Systems are Depleted from Plant Microbiota Genomes |
| 单细胞图谱的分布保留压缩：实现隐私保护数据传播与新细胞类型发现 |
Cai, Z. |
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N/A |
Distribution-preserved compression of single-cell atlases for privacy-protected data dissemination and novel cell type discovery |
| GOBoost：利用长尾基因本体论术语进行准确的蛋白质功能预测 |
Zhang, L. |
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N/A |
GOBoost: Leveraging Long-Tail Gene Ontology Terms for Accurate Protein Function Prediction |
| CD73抑制子宫内膜癌中突变型β-连环蛋白的致癌活性 |
Hirsch, R. M. |
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N/A |
CD73 restrains mutant β-catenin oncogenic activity in endometrial carcinomas |
| 酶约束的梅毒螺旋体代谢模型鉴定出甘油-3-磷酸脱氢酶作为替代电子汇 |
Shahreen, N. |
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N/A |
Enzyme-constrained Metabolic Model of Treponema pallidum Identified Glycerol-3-phosphate Dehydrogenase as an Alternate Electron Sink |
| 人巨细胞病毒预融合样糖蛋白B亚单位疫苗在小鼠中引发的体液免疫反应与融合后gB相似 |
Karthigeyan, K. P. |
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N/A |
A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits similar humoral immunity to that of postfusion gB in mice |
| 一种定量方法揭示了痘病毒感染中抗原呈递和免疫原性的普遍相关性，适用于病毒CD8+ T细胞表位 |
Witney, M. J. |
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N/A |
A quantitative approach to poxvirus infection reveals general correlates of antigen presentation and immunogenicity for viral CD8+ T cell epitopes |
| 在金黄色葡萄球菌中，sRNA介导的细胞壁压力与半乳糖代谢之间的交叉对话 |
Germain, M. |
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N/A |
sRNA-mediated crosstalk between cell wall stress and galactose metabolism in Staphylococcus aureus |
| 结合活细胞荧光成像与原位冷冻电子断层扫描技术，揭示了耐辐射奇异球菌（Deinococcus radiodurans）的隔膜形成过程。 |
Gaifas, L. |
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N/A |
Combining live cell fluorescence imaging with in situ cryo electron tomography sheds light on the septation process in Deinococcus radiodurans |
| SARS-CoV-2 亚变体 KP.3.1.1 和 XEC 的抗体逃逸性 |
Wang, Q. |
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N/A |
Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC |
| 结合代谢工程和发酵优化，通过Cutaneotrichosporon oleaginosus实现成本效益的油脂生产 |
Duman-Ozdamar, Z. E. |
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N/A |
Combining metabolic engineering and fermentation optimization to achieve cost-effective oil production by Cutaneotrichosporon oleaginosus |
| 癌症相关SF3B1突变K700E导致U2/分支点识别广泛变化，但不影响剪接。 |
Damianov, A. |
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N/A |
Cancer-associated SF3B1 mutation K700E causes widespread changes in U2/branchpoint recognition without altering splicing. |
| 生成 snoRNA 引导的可编程 2'O-甲基化 |
Zhao, J. |
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N/A |
Generating snoRNA-guided Programmable 2'O-methylation |
| CDKL5激酶通过富含丝氨酸的C端区域进行液-液相分离，而与神经发育疾病相关的截断则会对其造成损害。 |
Dell'Oca, M. |
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N/A |
The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region and impaired by neurodevelopmental disease-related truncations |
| Lrif1调节Trim28介导的小鼠胚胎干细胞中Dux位点的抑制作用 |
Sikrova, D. |
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N/A |
Lrif1 modulates Trim28-mediated repression of the Dux locus in mouse embryonic stem cells |
| 完整氨酰化tRNA的纳米孔测序 |
White, L. K. |
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N/A |
Nanopore sequencing of intact aminoacylated tRNAs |
| 渗透压膨胀的囊泡而非中间丝上的NLRP3支架促进了炎症小体的组装 |
de Paz Linares, G. A. |
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N/A |
Scaffolding of NLRP3 on osmotically swollen vesicles but not intermediate filaments promotes inflammasome assembly |
| 地球历史上固氮酶结构的演变 |
Cuevas, B. |
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N/A |
Nitrogenase structural evolution across Earth s history |
| 一种用于在真菌性脑膜炎病原体新生隐球菌中进行条件性突变的生长素诱导降解系统 |
Madhani, H. D. |
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N/A |
An auxin-inducible degron system for conditional mutation in the fungal meningitis pathogen Cryptococcus neoformans |
| 通过原位多聚腺苷酸化和空间RNA测序实现微生物群-宿主相互作用的高分辨率空间映射 |
Ntekas, I. |
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N/A |
High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing |
| 野生型和FMR1敲除的人类胚胎干细胞中核糖体的分析 |
Kharbanda, T. |
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N/A |
Analysis of ribosomes from the Wild-type and FMR1 knockout human embryonic stem cells |
| 3-甲基胞嘧啶修饰对神经元富集的精氨酸tRNA反密码子茎的结构影响 |
Berger, K. |
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N/A |
Structural impact of 3-methylcytosine modification on the anticodon stem of a neuronally-enriched arginine tRNA |
| 使用深度学习进行高亲和力蛋白质结合大环的精确从头设计 |
Rettie, S. |
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N/A |
Accurate de novo design of high-affinity protein binding macrocycles using deep learning |
| 无参考分析单细胞RNA测序数据揭示了在蝾螈神经发生过程中rRNA和mtRNA转录的升高 |
Ratul, M. R. Z. |
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N/A |
Reference-free Analysis of scRNA-seq Data Reveals Elevated rRNA and mtRNA Transcription during Neurogenesis in Axolotl |
| 高通量筛选揭示针对肺炎克雷伯菌和大肠杆菌中抗甲氧苄啶的DfrA1蛋白的潜在抑制剂 |
Hasnat, S. |
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N/A |
High-Throughput Screening Reveals Potential Inhibitors Targeting Trimethoprim-Resistant DfrA1 Protein in Klebsiella pneumoniae and Escherichia coli |
| Sphae：一种从测序数据中自动预测噬菌体疗法候选者的工具包 |
Papudeshi, B. |
PDF |
N/A |
Sphae: An automated toolkit for predicting phage therapy candidates from sequencing data |
| 军团菌肺炎杆菌对单一和多宿主的宿主特异性适应 |
Moreno, A. B. |
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N/A |
Host-specific adaptation of Legionella pneumophila to single and multiple hosts |
| 回到角的问题：通过不同类型的重组事件对祖先角状态的重建。 |
Upadhyay, M. |
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N/A |
Back to the horns: a reconstruction of the ancestral horn state through distinct types of recombination events. |
| 用于蛋白质组数据质询的归一化与方向性相互作用评分 |
Poncha, K. F. |
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N/A |
Normalized and Directional Interplay Scoring for the Interrogation of Proteoform Data |
| TAP2蛋白变异体的鉴定，这些变异体对HSV1 ICP47蛋白的抑制具有抗性 |
Nagy, G. |
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N/A |
Identification of TAP2 protein variants resistant to inhibition by the HSV1 ICP47 protein |
| 生物膜生活方式作为氨氧化古菌的共同特征 |
Dreer, M. |
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N/A |
Biofilm lifestyle as a common trait of ammonia-oxidizing archaea |