| JNK MAPK 调控化学耐药性、静止白血病细胞中的 IFN 刺激基因和细胞粘附 |
Lee, S. |
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N/A |
JNK MAPK Regulates IFN-Stimulated Genes and Cell Adhesion in Chemoresistant, Quiescent Leukemic Cells |
| 好妈妈：平原斑马中的依赖幼崽及其母亲比其他个体更能适应较长的旱季 |
Thel, L. |
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N/A |
Good moms: dependent-young and their mothers cope better than others with longer dry season in plains zebras |
| SUMO激活酶亚单位SAE2对有丝分裂保真性中的SUMO蛋白偏向性有贡献。 |
Walker, A. |
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N/A |
The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelity. |
| 淋巴结成纤维细胞表型及由Podoplanin活性调控的免疫交叉对话 |
Makris, S. |
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N/A |
Lymph node fibroblast phenotypes and immune crosstalk regulated by Podoplanin activity |
| 使用dreamlet进行大规模单细胞转录组数据的高效差异表达分析 |
Hoffman, G. E. |
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N/A |
Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet |
| N6-甲基腺苷（m6A）促进具有完整5'剪接位点基序的mRNA在细胞核中的保留 |
Lee, E. S. |
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N/A |
N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs |
| 农药诱导的褐飞虱再猖獗是通过影响一系列促进保幼激素生物合成和雌性生殖力的基因而介导的。 |
Gao, Y. |
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N/A |
Pesticide-induced resurgence in brown planthopper is mediated by action on a suite of genes that promote juvenile hormone biosynthesis and female fecundity |
| APOBEC3活性促进肺癌中获得性耐药EGFR抑制剂期间耐药持久细胞的存活和进化 |
Garcia, N. M. G. |
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N/A |
APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer |
| 中介激酶抑制剂抑制唐氏综合征中过度活跃的干扰素信号传导 |
Cozzolino, K. |
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N/A |
Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome |
| 在自然音乐聆听过程中映射多模态动态网络活动 |
Faber, S. E. |
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N/A |
Mapping multi-modal dynamic network activity during naturalistic music listening |
| 高置信度糖体膜蛋白清单揭示了锥虫中的过氧化物酶体蛋白PEX15 |
Krishna, C. K. |
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N/A |
High confidence glycosomal membrane protein inventory unveils trypanosomal Peroxin PEX15 |
| 在运动执行和运动规划过程中，控制策略可以根据任务需求进行调整。 |
Orban de Xivry, J.-J. |
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N/A |
A control policy can be adapted to task demands during both motor execution and motor planning |
| Oct4 与 Sox2 之间的新兴协同作用调控着早期小鼠胚胎中的多能性网络。 |
Hou, Y. |
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N/A |
Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos |
| 评估不同突变发现方法之间的不一致体细胞突变，以最大限度减少假阴性耐药性发现 |
Lin, H.-F. |
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N/A |
Evaluating discordant somatic calls across mutation discovery approaches to minimize false negative drug-resistant findings |
| 基于电导的神经元模型中高去极化基线偏移的机制与意义 |
Kumar, A. |
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N/A |
Mechanisms and implications of high depolarization baseline offsets in conductance-based neuronal models |
| 共受体Tetraspanin12直接捕获Norrin以促进配体特异性的β-连环蛋白信号传导 |
Bruguera, E. S. |
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N/A |
The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling |
| 全球多样性与进化：巴拿马沙门氏菌——一种全球范围内引起胃肠道和侵袭性疾病但研究不足的血清型：一项基因组流行病学研究 |
Pulford, C. V. |
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N/A |
Global diversity and evolution of Salmonella Panama, an understudied serovar causing gastrointestinal and invasive disease worldwide: a genomic epidemiology study |
| 白血病的侵袭性受染色质重塑和核心调控因子表达变化所驱动。 |
Bonilla, G. |
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N/A |
Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators |
| 在视觉-正字法预测误差表征中指定精度，以更好地理解高效阅读 |
Fu, W. |
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N/A |
Specifying precision in visual-orthographic prediction error representations for a better understanding of efficient reading |
| 蜜蜂嗉囊中的细菌与花蜜和蜜蜂口腔中的细菌不相关。 |
Warren, M. L. |
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N/A |
Bacteria in honeybee crops are decoupled from those in floral nectar and bee mouths |
| 成年神经发生协调了嗅觉感知记忆的灵活性和稳定性 |
Sakelaris, B. |
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N/A |
Adult Neurogenesis Reconciles Flexibility and Stability of Olfactory Perceptual Memory |
| 性染色体的进化与物种形成的两个规则的单一理论 |
Lenormand, T. |
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N/A |
A single theory for the evolution of sex chromosomes and the two rules of speciation |
| 动物物种间SARS-CoV-2的宿主内遗传多样性 |
Naderi, S. |
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N/A |
Within-host genetic diversity of SARS-CoV-2 across animal species |
| 不同的秀丽隐杆线虫毒素等位基因通过不同的机制被抑制 |
Zdraljevic, S. |
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N/A |
Divergent C. elegans toxin alleles are suppressed by distinct mechanisms |
| CetZ1依赖的极性运动机器在嗜盐古菌中的组装 |
Brown, H. J. |
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N/A |
CetZ1-dependent polar assembly of the motility machinery in haloarchaea |
| MYB68调控径向内胚层分化及木栓质模式形成 |
Kraska, L. |
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N/A |
MYB68 regulates radial endodermal differentiation and suberin patterning |
| KCa3.1的早期新型精氨酸甲基化减弱了后续T细胞的耗竭。 |
Sharma, P. |
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N/A |
An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion. |
| 降低腹内侧下丘脑（VMH）中神经型一氧化氮合酶（nNOS）的表达会增加雌性小鼠的体重和血糖水平，同时降低其身体活动。 |
Hirschberg, P. R. |
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N/A |
Reducing neuronal nitric oxide synthase (nNOS) expression in the ventromedial hypothalamus (VMH) increases body weight and blood glucose levels while decreasing physical activity in female mice. |
| 可扩展、高质量工程化干细胞衍生的SIRPα-细胞外囊泡的双模态作用治疗急性肝衰竭 |
Kim, S. |
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N/A |
Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure |
| 控制Ins2基因活性和β细胞状态转换的信号转导通路 |
Chu, J. |
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N/A |
Signal transduction pathways controlling Ins2 gene activity and β cell state transitions |
| 鉴定用于神经退行性疾病治疗的新型小分子伴侣激活剂 |
Ho, A. |
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N/A |
Identification of novel small molecule chaperone activators for neurodegenerative disease treatment |
| 食管腺癌的化生前体状态代表了在发育中的食管中向短暂的上皮细胞状态的逆转。 |
Baker, S. |
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N/A |
The metaplastic precursor state to oesophageal adenocarcinoma represents reversion to a transient epithelial cell state in the developing oesophagus |
| 人类新生儿超越词汇的统计学习 |
Flo, A. |
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N/A |
Statistical learning beyond words in human neonates |
| 克服毒性：为何繁荣与衰退周期对非对抗性微生物有益 |
Wang, M. |
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N/A |
Overcoming toxicity: why boom-and-bust cycles are good for non-antagonistic microbes |
| 鳃组织活检的转录组分析以确定养殖大西洋鲑鱼海水存活率的预测标志物 |
Gronvold, L. |
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N/A |
Transcriptomic profiling of gill biopsies to define predictive markers for seawater survival in farmed Atlantic salmon |
| 增殖事件改善了造血干细胞中DNA损伤的积累，而不影响其功能。 |
Mehatre, S. H. |
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N/A |
Proliferative events ameliorate DNA damage accumulation without affecting function in hematopoietic stem cells |
| 物体非刚性的各向异性：皮层各向异性对高级感知的影响 |
Maruya, A. |
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N/A |
Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy |
| 本科生研究学生使用的ChatGPT辅助阅读协议 |
Sambar, M. |
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N/A |
A ChatGPT Assisted Reading Protocol for Undergraduate Research Students |
| 结构引导的循环嫁接技术提高了流感神经氨酸酶在疫苗开发中的表达和稳定性 |
Rijal, P. |
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N/A |
Structure-Guided Loop Grafting Improves Expression and Stability of Influenza Neuraminidase for Vaccine Development |
| 一种流行性Ralstonia solanacearum谱系的兴起及其宿主范围的扩展 |
Evseeva, D. |
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N/A |
Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum |
| 使用稳定同位素示踪法建模复合脂质稳态 |
Wessendorf-Rodriguez, K. |
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N/A |
Modeling Compound Lipid Homeostasis Using Stable Isotope Tracing |
| 在主要外排敲除系统中确定铜绿假单胞菌MexXY-OprM底物谱，揭示了不同的抗生素底物类别 |
Kavanaugh, L. G. |
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N/A |
Determination of Pseudomonas aeruginosa MexXY-OprM substrate profile in a major efflux knockout system reveals distinct antibiotic substrate classes |
| 基于纵向微生物组的可解释机器学习用于早期疾病结果预测中时变生物标志物的识别 |
Dai, Y. |
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N/A |
Longitudinal Microbiome-based Interpretable Machine Learning for Identification of Time-Varying Biomarkers in Early Prediction of Disease Outcomes |
| 罕见癌症靶点发现框架 |
Li, B. |
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N/A |
A framework for target discovery in rare cancers |
| 生物医学数据的AI准备：Bridge2AI建议 |
Clark, T. |
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N/A |
AI-readiness for Biomedical Data: Bridge2AI Recommendations |
| 听觉皮层中的正交频谱和时间包络表示 |
Takahashi, K. |
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N/A |
Orthogonal spectral and temporal envelope representation in auditory cortex |
| 海葵生命史中基质分子动力学 |
Bergheim, B. G. |
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N/A |
Molecular dynamics of the matrisome across sea anemone life history |
| 神经肌肉骨骼建模流程：基于MATLAB的OpenSim模型个性化与治疗优化功能 |
Hammond, C. V. |
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N/A |
The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim |
| 定义细胞类型特异性CTCF结合和染色质组织的基因组范围代码 |
Do, C. |
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N/A |
A genome wide code to define cell-type specific CTCF binding and chromatin organization |
| 微生物群落中的对抗作为一种觅食策略 |
Stubbusch, A. K. M. |
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N/A |
Antagonism as a foraging strategy in microbial communities |
| 脊椎动物R2逆转录转座子复合物在目标引导逆转录期间的结构及第二链切割后的结构 |
Thawani, A. |
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N/A |
Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking |
| 通过结构建模和分歧日期估算，理解植物和真菌病毒中RNA聚合酶的进化和功能关系 |
Gracy, J. |
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N/A |
Understanding evolutionary and functional relationships of RNA polymerases in plant and fungal viruses through structural modeling and divergence date estimations |
| 对玉米驯化过程中根系表型在特瓦坎新石器时代土壤中的演变进行计算机模拟分析 |
Lopez-Valdivia, I. |
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N/A |
In silico analysis of the evolution of root phenotypes during maize domestication in Neolithic soils of Tehuacan |
| 基于结冷胶的营养培养基增加了土壤微生物培养群的多样性 |
Kulikova, D. |
PDF |
N/A |
Gellan gum-based nutrient medium increases the diversity of cultivated groups of soil microorganisms |
| 与越南H5N1分离株相比，牛H5N1在小鼠中表现出增强的脑炎趋向性。 |
Goldin, K. |
PDF |
N/A |
Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice |
| 磁共振R2*捕捉中风后不连续脑结构中的炎症：一项转化研究 |
Koubiyr, I. |
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N/A |
MRI R2* captures inflammation in disconnected brain structures after stroke: a translational study |
| 在BSL2级别下，使用直接薄层琼脂进行结核分枝杆菌对贝达喹啉的敏感性测试，从痰液处理开始15天内可获得高准确性。 |
Cuella Martin, I. |
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N/A |
Direct thin-layer agar for bedaquiline-susceptibility testing of Mycobacterium tuberculosis at BSL2 level yields high accuracy in 15 days from sputum processing. |
| 野生大麦多样性全基因组测序：用于鉴定和利用遗传变异以改良栽培大麦的资源 |
Sallam, A. H. |
PDF |
N/A |
Whole-Genome Sequencing of the Wild Barley Diversity Collection: A Resource for Identifying and Exploiting Genetic Variation for Cultivated Barley Improvement |
| 基于基因表达的膀胱癌淋巴结转移预测因子评估 |
Johansson, H. B. |
PDF |
N/A |
Evaluation of gene expression-based predictors of lymph node metastasis in bladder cancer |
| 委内瑞拉十一种无尾两栖动物的体型变异与性二态性 |
Canizales, I. |
PDF |
N/A |
Body Size Variation And Sexual Dimorphism In Eleven Species Of Venezuelan Anurans |
| 分子脑老化新多基因风险评分的神经结构和认知特征 |
Clifford, K. P. |
PDF |
N/A |
Neurostructural and cognitive signatures of novel polygenic risk scores for molecular brain aging |
| 内源性LINE-1蛋白及ORF2p相互作用的靶向检测 |
Nielsen, M. I. |
PDF |
N/A |
Targeted detection of endogenous LINE-1 proteins and ORF2p interactions |
| Nano3P-seq：以单分子分辨率绘制编码和非编码转录组图谱 |
Begik, O. |
PDF |
N/A |
Nano3P-seq: charting the coding and non-coding transcriptome at single molecule resolution |
| SuperWater：利用生成式AI预测蛋白质结构上的水分子位置 |
Kuang, X. |
PDF |
N/A |
SuperWater: Predicting Water Molecule Positions on Protein Structures by Generative AI |
| 通过抑制或降解LZK来靶向GOF p53和c-MYC抑制头颈肿瘤生长 |
Funk, A. L. |
PDF |
N/A |
Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth |
| 发育程序中的重复超基序电路 |
Adler, M. |
PDF |
N/A |
Recurrent hyper-motif circuits in developmental programs |
| AZIN2依赖的多胺代谢决定脂肪细胞前体细胞的命运，并保护机体免受肥胖和代谢紊乱的影响。 |
Mund, C. |
PDF |
N/A |
AZIN2-dependent polyamine metabolism determines adipocyte progenitor fate and protects against obesity and dysmetabolism |
| 冰滑硅藻创下了真核细胞运动最低温度限制的纪录 |
Zhang, Q. |
PDF |
N/A |
Ice gliding diatoms establish record-low temperature limit for motility in a eukaryotic cell |
| Boltz-1：使生物分子相互作用建模民主化 |
Wohlwend, J. |
PDF |
N/A |
Boltz-1: Democratizing Biomolecular Interaction Modeling |
| 修改聚集状态可能会提高Ozempic的活性。 |
Bolano Alvarez, A. |
PDF |
N/A |
Modifying the aggregation state may improve the activity of Ozempic |
| 片状伪足中动态稳态的机制 |
Kim, J. H. |
PDF |
N/A |
The Mechanism of Dynamic Steady States in Lamellipodia |
| 细胞分裂过程中染色体形态的渐进变化，通过环捕获模拟再现 |
Kakui, Y. |
PDF |
N/A |
Progressive chromosome shape changes during cell divisions, recapitulated by loop capture simulations |
| 通过细胞内丝状体感知表面形状 |
Shi, H. |
PDF |
N/A |
Sensing the shape of a surface by intracellular filaments |
| 分枝杆菌脂阿糖甘露聚糖负向干扰巨噬细胞对烟曲霉的体外反应 |
Gonzales-Huerta, L. E. |
PDF |
N/A |
Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro |
| 精氨酸调控超毒力肺炎克雷伯菌的黏液表型 |
Ring, B. E. |
PDF |
N/A |
Arginine Regulates the Mucoid Phenotype of Hypervirulent Klebsiella pneumoniae |
| 学习单细胞转录组数据的多细胞表示，有助于表征患者层面的疾病状态。 |
Liu, T. |
PDF |
N/A |
Learning multi-cellular representations of single-cell transcriptomics data enables characterization of patient-level disease states |
| 外周来源巨噬细胞的命运图谱揭示，在创伤性脑损伤后长达8个月的时间里，存在一群持久植入的细胞，这些细胞维持着独特的转录组特征。 |
Paladini, M. S. |
PDF |
N/A |
Fate mapping of peripherally derived macrophages reveals a long-lasting engrafted population that maintains a distinct transcriptomic profile for up to 8 months after Traumatic Brain Injury |
| 根瘤菌能否缓解豆科植物受到气候介导的微生物群落效应的影响？ |
Boyle, J. A. |
PDF |
N/A |
Do rhizobia buffer legumes against climate-mediated microbiome effects? |
| 揭示隐藏的盛宴：将分子检测转化为捕食率——农业生态系统中广食性捕食者生物防治的一个实例。 |
MASSON, A. L. |
PDF |
N/A |
Unveiling the Hidden Feast: translating molecular detection into predation rate. An example on biological control by generalist predators in agricultural fields. |
| 伊维菌素残留对粪便昆虫的依赖于环境背景的影响：与环境压力源、体型和性别在一种腐蝇（Sepsis neocynipsea）中的相互作用 |
Walker, J. |
PDF |
N/A |
Context-dependent effects of ivermectin residues on dung insects: Interactions with environmental stressors, size, and sex in a sepsid fly (Sepsis neocynipsea) |
| 关于非随机交配、适应性进化与信息论 |
Carvajal-Rodriguez, A. |
PDF |
N/A |
On non-random mating, adaptive evolution and information theory |
| 行波划动在雷诺数变化四个数量级的情况下仍能提供强大的推进性能。 |
Ford, M. P. |
PDF |
N/A |
Metachronal rowing provides robust propulsive performance across four orders of magnitude variation in Reynolds number |
| 利用AlphaFold 3进行神经疾病相关蛋白质的结构建模：通向精准医学的路径 |
Gadde, N. |
PDF |
N/A |
Leveraging AlphaFold 3 for Structural Modeling of Neurological Disorder-Associated Proteins: A Pathway to Precision Medicine |
| 使用向量符号架构进行特征选择：结直肠癌 shotgun 宏基因组样本微生物特征的案例研究 |
Cumbo, F. |
PDF |
N/A |
Feature selection with vector-symbolic architectures: a case study on microbial profiles of shotgun metagenomic samples of colorectal cancer |
| 原子模拟揭示线粒体ATP合酶中ATP酶抑制因子1的旋转方向依赖性调控 |
Kobayashi, R. |
PDF |
N/A |
Rotation-direction-dependent regulation of ATPase inhibitory factor 1 for mitochondrial ATP synthase from atomistic simulation |
| 癌症相关DAXX突变揭示了ATRX定位在ALT抑制中的关键作用 |
Clatterbuck Soper, S. F. |
PDF |
N/A |
Cancer-associated DAXX mutations reveal a critical role for ATRX localization in ALT suppression |
| 网络毒理学聚焦研究无机砷和镉对人类和生态系统健康的影响 |
Chivukula, N. |
PDF |
N/A |
Network toxicology focused investigation on the impacts of inorganic arsenic and cadmium on human and ecosystem health |
| Sigma配体介导的BV2小胶质细胞胞质钙调制 |
Lodholz, E. |
PDF |
N/A |
Sigma Ligand-mediated Cytosolic Calcium Modulation in BV2 Microglia Cells |
| 一个TORC1-PHR1信号轴调控拟南芥中的磷饥饿与免疫信号网络 |
Awasthi, P. |
PDF |
N/A |
A TORC1-PHR1 signaling axis regulates phosphorus starvation and immunity signaling network in Arabidopsis |
| 转录反终止作用整合了在嵌合的巴尔通体基因转移因子BaGTA中源自不同噬菌体基因座的表达 |
Korotaev, A. |
PDF |
N/A |
Transcriptional antitermination integrates the expression of loci of diverse phage origin in the chimeric Bartonella Gene Transfer Agent BaGTA |
| 优化从鼻腔衬液中提取DNA以使用第三代测序评估鼻腔微生物群 |
Montgomery, S. T. |
PDF |
N/A |
Optimisation of DNA extraction from nasal lining fluid to assess the nasal microbiome using third-generation sequencing |
| 丝状化图谱揭示了几个转录调控因子，这些因子导致了白色念珠菌和都柏林念珠菌之间的差异。 |
Meza-Davalos, T. |
PDF |
N/A |
Filamentation profile reveals several transcription regulators that contribute to differences between Candida albicans and Candida dubliniensis |
| 人巨细胞病毒pp65的蛋白质-S-亚硝基化降低了其削弱cGAS的能力。 |
Cox, J. B. |
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Protein-S-Nitrosylation of Human Cytomegalovirus pp65 Reduces its Ability to Undermine cGAS. |
| 通过灵活的顺反相互作用快速重塑古菌转录因子功能 |
Martinez-Pastor, M. |
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N/A |
Rapid rewiring of an archaeal transcription factor function via flexible cis-trans interactions |
| JN.1单价mRNA疫苗诱导了针对包括JN.1、KP.3.1.1和XEC在内的广泛SARS-CoV-2 Omicron亚变种的强健抗病毒体液免疫。 |
Uriu, K. |
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Robust antiviral humoral immunity induced by JN.1 monovalent mRNA vaccines against a broad range of SARS-CoV-2 Omicron subvariants including JN.1, KP.3.1.1 and XEC |
| 结合CRISPR激活和干扰能力，利用dCas9和G-四链体结构 |
Kabir, M. L. |
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Combining the CRISPR Activation and Interference Capabilities Using dCas9 and G-Quadruplex Structures |
| 一种综合方法：研究蜱虫幼虫和若虫叮咬小鼠以探讨莱姆病传播与感染 |
Scholl, A. |
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A Comprehensive Method on Black-legged Tick Larvae and Nymph Feeding on Mice to Study Lyme Disease Transmission and Acquisition |
| 组蛋白修饰和转座元件在基因重复后剂量表观遗传调控中的作用 |
Wolfe, T. D. |
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The role of histone modifications and transposable elements in the epigenetic regulation of dosage after gene duplication |
| 复杂性状尾部的多基因结构显著偏离 |
Souaiaia, T. |
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N/A |
Striking Departures from Polygenic Architecture in the Tails of Complex Traits |
| 环节动物管虫Galeolaria caespitosa的分阶段染色体水平基因组 |
Van Dorssen, M. |
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N/A |
A phased chromosome-level genome of the annelid tubeworm Galeolaria caespitosa |
| 大肠杆菌天冬氨酸转氨甲酰酶的核苷酸依赖性变构调节机制 |
Miller, R. C. |
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N/A |
Mechanism of Nucleotide-Dependent Allosteric Regulation in Escherichia coli Aspartate Transcarbamoylase |
| 卵巢癌失调的长非编码RNA中的G四链体结构及其与人血清白蛋白的结合相互作用 |
Singh, D. |
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G-quadruplex Structures in Dysregulated Long Non-Coding RNA of Ovarian Cancer and their Binding Interactions with Human Serum Albumin |
| 经过工程改造的线粒体A-to-G编辑器，具有增强的效率和靶向范围 |
Chen, L. |
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N/A |
Engineered mitochondrial A-to-G editors with enhanced efficiency and targeting scope |
| 通过可植入无线OLEDs进行深部器官癌症的光动力疗法 |
Itazaki, Y. |
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N/A |
Photodynamic Therapy for Deep Organ Cancer by Implantable Wireless OLEDs |
| 计算机辅助多层次优化假单胞菌中丙二酰辅酶A的可用性 |
Batianis, C. |
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Computer assisted multi-level optimization of malonyl-CoA availability in Pseudomonas putida |
| 发现组织和维持神经回路的可塑性规则 |
Bell, D. |
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Discovering plasticity rules that organize and maintain neural circuits |
| 肽聚合物二级结构在抗菌效力和抗生素增效中的作用 |
Barman, S. |
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N/A |
The role of secondary structures of peptide polymers on antimicrobial efficacy and antibiotic potentiation |
| 古菌细胞周期的转录图谱在真核生物中广泛保守 |
Gomez-Raya-Vilanova, M. V. |
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Transcriptional landscape of the archaeal cell cycle is broadly conserved in eukaryotes |
| 化学恒化培养法可降低粪便真核病毒载量，并延缓病毒组移植后的腹泻发生。 |
Offersen, S. M. |
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Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation |
| 在基于肠道的阿尔茨海默病果蝇模型中产生的Abeta聚集物的多样性 |
Elovsson, G. |
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Diversity of Abeta aggregates produced in a gut-based Drosophila model of Alzheimer's disease |
| 心脏p38抑制突显磷酸蛋白质组在心力衰竭进展中的作用 |
Sedighi, S. |
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Inhibition of Cardiac p38 Highlights the Role of the Phosphoproteome in Heart Failure Progression |
| SARS-CoV-2 Spike蛋白跨膜区的序列和结构完整性对于病毒进入宿主细胞至关重要。 |
Ortiz-Mateu, J. |
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The sequence and structural integrity of the SARS-CoV-2 Spike protein transmembrane domain is crucial for viral entry |
| 一种可诱导Cre和Flp组合重组的顺序事件响应型荧光报告系统 |
Pessina, G. |
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A sequential event-responsive fluorescent reporter for inducible Cre and Flp combinatorial recombination |
| 人类eIF2A在翻译起始和uORF介导的翻译调控中起着微小的作用。 |
Teleman, A. A. |
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Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control |
| 冷诱导的GOT1在棕色脂肪组织中激活苹果酸-天冬氨酸穿梭，以支持对脂肪酸的燃料偏好。 |
Park, C.-H. |
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Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids |
| 对多样性杂交小鼠研究中的寿命进行分析，发现了多个与长寿相关的基因座 |
Mullis, M. N. |
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Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci |
| PHRF1的PHD指对组蛋白H3 N端识别对于适当的DNA损伤反应是必需的。 |
Jain, K. |
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Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response |
| SPO11二聚化调控减数分裂DNA双链断裂的形成 |
Oger, C. A. |
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SPO11 dimerization controls meiotic DNA double-strand break formation |
| 利用密度和能量引导评估，自动识别冷冻电镜数据中的小分子 |
Muenks, A. |
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Automated identification of small molecules in cryo-electron microscopy data with density- and energy-guided evaluation |
| 一个评估肉类替代品的建议框架 |
Semper, C. |
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A proposed framework for evaluating meat alternatives |
| 评估当前长读长宏基因组菌株解析工具的性能 |
Afolayan, A. O. |
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Assessing the performance of current strain resolution tools on long-read metagenomes |
| 等离子体激活水对百脉根丛枝菌根共生关系的调节作用 |
Cortese, E. |
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Modulatory effect of plasma-activated water on arbuscular mycorrhizal symbiosis in Lotus japonicus |
| 渔猫化学通讯的功能性见解：半水生栖息地适应的策略机制 |
Das, S. |
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Functional insights on chemical communication of fishing cats: a strategic mechanism for adaptation in semi-aquatic habitat |
| 多模态测量的整合揭示了结核病药物作用的关键机制 |
Johnson, W. C. |
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Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action |
| 移植地点对在家与在医院接受造血干细胞移植患者的肠道微生物群和抗性组的影响 |
Andermann, T. M. |
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The impact of transplant location on the gut microbiome and resistome in patients undergoing hematopoietic stem cell transplantation at home versus in the hospital |
| RNA聚合酶II亚基的过表达会引发基因组不稳定性并扰乱转录调控。 |
Sadurni, M. M. |
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RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription |
| 基于多组学的2D和3D人类iPSC-心肌细胞胰岛素抵抗模型评估显示，其代谢和收缩功能障碍再现了糖尿病心肌病的特征。 |
Carter, R. D. |
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Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. |
| 浮游植物光合生理学揭示了特定深度的浮游动物摄食情况 |
Graff, J. R. |
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Phytoplankton Photophysiology Reveals Depth Specific Zooplankton Grazing |
| 本地和入侵植物群落中蜱虫暴露风险的机制途径 |
Hiatt, D. |
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N/A |
Mechanistic pathways of tick exposure risk in native and invaded plant communities |
| 负韧性趋势导致地中海橡树物种更频繁的极端干旱 |
Vazquez, I. B. |
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N/A |
Negative resilience trends to more frequent extreme droughts in Mediterranean oak species |