| 量化种内性状变异和种间性状相关性对相互作用种群的影响——一种非线性平均方法 |
van Benthem, K. J. |
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Quantifying the effects of intraspecific trait variation and interspecific trait correlations on interacting populations - a nonlinear averaging approach |
| 通过基因拷贝数变异揭示的尼安德特人、丹尼索瓦人和智人的遗传饮食适应性 |
Vicedomini, R. |
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N/A |
Genetic dietary adaptation in Neandertal, Denisovan and Sapiens revealed by gene copy number variation |
| 一个基于网络的水生指示物种大型溞组织学图谱 |
Ngu, M. S. |
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N/A |
A web-based histology atlas for the freshwater sentinel species Daphnia magna |
| 腹侧视觉通路中的有机卷积可以解释V4区形状调谐的多样性 |
Gold, C. S. |
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Organic Convolution in The Ventral Visual Pathway Can Explain the Variety of Shape Tuning in Area V4 |
| 泛素化蛋白质组分析鉴定卡波西肉瘤疱疹病毒裂解再激活中的新宿主因子 |
Causey, A. |
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Analysis of the ubiquitin-modified proteome identifies novel host factors in Kaposi's sarcoma herpesvirus lytic reactivation |
| 动作电位的消亡导致神经元之间的电耦合 |
Schloetter, M. |
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Annihilation of action potentials induces electrical coupling between neurons |
| 海马体中相关事件的区分有助于记忆在发育过程中的再激活 |
Varga, N. L. |
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Differentiation of related events in hippocampus supports memory reinstatement in development |
| SARS-CoV-2感染人多能干细胞衍生的血管细胞揭示了平滑肌细胞在感染期间作为血管病理学的关键介质。 |
Richards, A. |
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SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection |
| 小鼠8细胞胚胎中启动了一波新的DNA甲基化，与H3K27me3共同调控印记X染色体失活。 |
Yue, Y. |
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A wave of minor de novo DNA methylation initiates in mouse 8-cell embryos and co-regulates imprinted X- chromosome inactivation with H3K27me3 |
| 寄生虫复杂生命周期中的多重感染 |
Nguyen, P. L. |
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On multiple infections by parasites with complex life cycles |
| 胶质母细胞瘤和其他颅内肿瘤会引发全身性的交感神经活动过度，从而限制了免疫治疗的效果。 |
Lorrey, S. J. |
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Glioblastoma and other intracranial tumors elicit systemic sympathetic hyperactivity that limits immunotherapeutic responses |
| Meteorins调节左右组织者的形成以及脊椎动物身体不对称性的建立。 |
Eggeler, F. |
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Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry |
| 压应力通过侧向张力和Piezo1驱动形态发生性凋亡 |
Merle, T. |
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Compressive stress drives morphogenetic apoptosis through lateral tension and Piezo1 |
| RNAformer：一种简单而有效的同源性感知RNA二级结构预测模型 |
Franke, J. K. H. |
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RNAformer: A Simple yet Effective Model for Homology-Aware RNA Secondary Structure Prediction |
| 在隐球菌中，Shugoshin对Bub1激酶活性的依赖对于维持纺锤体组装检查点反应并非必需。 |
Polisetty, S. D. |
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The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans |
| 单倍体型解析的癌症核型重建与功能解析 |
Brunette, G. J. |
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Haplotype-resolved reconstruction and functional interrogation of cancer karyotypes |
| HSV-1感染导致+1核小体的下游移位 |
Weiss, E. |
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HSV-1 infection induces a downstream-shift of the +1 nucleosome |
| 利用直接RNA测序技术探究酶依赖的假尿苷酸化，以评估神经元表转录组的可塑性 |
Fanari, O. |
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Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess neuronal epitranscriptome plasticity |
| 机械力通过mTORC2-PKC途径调控心内膜Notch活化 |
Mu, Y. |
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Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway |
| 睫状蛋白IFT88的时间性消融改变了正常的脑电波模式 |
Strobel, M. R. |
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Temporal Ablation of the Ciliary Protein IFT88 Alters Normal Brainwave Patterns |
| 在活体中对鸟类上皮应用组织尺度的张力，以研究多尺度力学和胚层间耦合 |
Oikonomou, P. |
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Application of tissue-scale tension to avian epithelia in vivo to study multiscale mechanics and inter-germ layer coupling |
| 非超突变癌症通过逆转种系突变偏倚来获得驱动突变。 |
Tuffaha, M. Z. |
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Non-hypermutator cancers access driver mutations through reversals in germline mutational bias |
| 使用纳米孔直接RNA测序（DRS）进行mRNA psi图谱分析揭示了细胞类型特异性的假尿苷酸化 |
McCormick, C. A. |
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mRNA psi profiling using nanopore DRS reveals cell type-specific pseudouridylation |
| 叶绿体单线态氧信号通过植物U-Box 4介导，导致RNA全局变化，叶绿体铁螯合酶二突变体的转录组分析揭示了这一过程。 |
Rai, S. |
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Transcript profiling of plastid ferrochelatase two mutants reveals that chloroplast singlet oxygen signals lead to global changes in RNA profiles and are mediated by Plant U-Box 4 |
| 快速进化转变和重叠的性偏倚基因表达模式变异使得性别的简单二元分类变得困难。 |
Xie, C. |
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Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary classification of sexes |
| PEX14在人类细胞中作为连接optineurin和peroxisome自噬的分子桥梁。 |
Li, H. |
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PEX14 functions as a molecular link between optineurin and pexophagy in human cells |
| 静水流深：形态保守的多板纲动物进化中的大规模基因组重排 |
Sigwart, J. D. |
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Still waters run deep: Large scale genome rearrangements in the evolution of morphologically conservative Polyplacophora |
| 因果、预测还是观察？不良结局路径中关键事件关系的不同理解及其对实践的影响 |
Zhou, Z. |
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Causal, Predictive or Observational? Different Understandings of Key Event Relationships for Adverse Outcome Pathways and Their Implications on Practice |
| 重建自始新世以来欧亚淡水鱼类（鳅科）的系统发育和进化历史 |
Slechtova, V. |
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Reconstructing the phylogeny and evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene |
| 人类微生物组来源的肽通过分子模拟影响实验性自身免疫性脑脊髓炎的发展 |
Ma, X. |
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Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicry |
| 持久、私有和移动基因：进化泛基因组中基因动态模型 |
Gamblin, J. |
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Persistent, Private and Mobile genes: a model for gene dynamics in evolving pangenomes |
| 重塑信息格局：将Waddington景观应用于衰老信息论与表观遗传再生 |
Wu, Y. |
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Transform the Information Landscape: Applying Waddington Landscape to Information Theory of Aging and Epigenetic Rejeuvanation |
| 整合分子动力学模拟解析交联数据，揭示线粒体蛋白质分布 |
Schuhmann, F. |
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Integrative Molecular Dynamics Simulations Untangle Cross-Linking Data to Unveil Mitochondrial Protein Distributions |
| 鸟类词汇地图集：一个全球英语鸟类名称描述性类别数据库 |
Morrison, E. S. |
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AvianLexiconAtlas: A database of descriptive categories of English-language bird names around the world |
| 对单极刷状细胞施加逼真的苔藓纤维输入模式，会引发一系列时间响应，这些响应由不同谷氨酸受体介导的成分组成。 |
Huson, V. |
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Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors |
| 在人类肺癌恶病质的新型临床前模型中，早期脂肪组织消耗 |
Snoke, D. B. |
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Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia |
| 环氧化酶-2的破坏易导致保留射血分数的心力衰竭 |
Ricciotti, E. |
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Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction |
| 确定内在无序蛋白质在原子分辨率下的精确构象集合 |
Borthakur, K. |
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Determining accurate conformational ensembles ofintrinsically disordered proteins at atomic resolution |
| p62纤维的结构组织及富含钙的p62包裹脂滴货物的细胞超微结构 |
Berkamp, S. |
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Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo |
| 阿拉斯加红藻Devaleraea mollis和Palmaria hecatensis的培养方案 |
Dittrich, M. |
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Cultivation protocols the rhodophytes, Devaleraea mollis and Palmaria hecatensis from Alaska |
| 开发自主神经系统多尺度神经连接知识库 |
Imam, F. T. |
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Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System |
| 揭示椋鸟群集体逃逸的机制 |
Papadopoulou, M. |
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N/A |
Revealing mechanisms underlying the collective escape of starling flocks |
| 细菌核糖体药物结合残基的自然变异 |
Ekemezie, C. L. |
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N/A |
Natural variation in the drug-binding residues of bacterial ribosomes |
| 基因尺度体外重建揭示组蛋白乙酰化直接调控染色质结构 |
Fukai, Y. |
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Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture |
| 血管转录因子TMO5调控PIN1极性和器官发生，位于茎尖分生组织中MONOPTEROS的下游 |
Kareem, A. |
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Vascular Transcription Factor TMO5 Regulates PIN1 Polarity andOrganogenesis Downstream of MONOPTEROS in the Shoot Meristem |
| 晚更新世巴西东南部灰侏儒鹿摄食策略的千年尺度稳定性。 |
Hubbe, A. |
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Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil. |
| 注意你的光谱：验证同位素组蛋白肽段形式鉴定时需要注意的要点 |
Hijazi, H. |
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Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms |
| 鉴定和表征类衣原体细菌Simkania negevensis的泛素E3 RING连接酶 |
Hörner, E.-M. |
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Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis |
| 协调蛋白模块在人卵巢癌模型中单细胞分辨率下定义卡铂诱导的DNA损伤反应 |
Bedia, J. S. |
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Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models |
| 两种入侵性蚧虫（铁杉毛蚧和菠萝瘿蚧）的基因组使得对烟碱型乙酰胆碱受体的特征描述成为可能。 |
Glendening, A. M. |
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Genomes of two invasive Adelges species (hemlock woolly adelgid and pineapple gall adelgid) enable characterization of nicotinic acetylcholine receptors |
| 同时抑制COX-1和COX-2不足以引发与长期使用非甾体抗炎药相关的肠病。 |
Barekat, K. |
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Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use |
| 结核分枝杆菌中一种新型放线菌特异性核糖体休眠因子 |
Majumdar, S. |
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A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis |
| 线粒体自噬有助于维持细胞质蛋白质稳态，以保护心脏功能 |
Diwan, A. |
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N/A |
Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function |
| 脂肪源性间充质干细胞与视网膜色素上皮细胞在应激环境中的相互作用通过隧道纳米管进行 |
Gozel, M. |
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Adipose-derived Mesenchymal Stem Cells and Retinal Pigment Epithelial Cells Interactions in Stress Environment via Tunneling Nanotubes |
| 自噬抑制在低氧条件下诱导急性髓系白血病细胞死亡并增强化疗效果 |
Wang, E. S. |
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N/A |
Autophagy inhibition induces AML cell death and enhances the efficacy of chemotherapy under hypoxia |
| S100A4和TIGIT的联合抑制通过激活T细胞和NK细胞抑制晚期乳腺癌向肺部的转移 |
Leu, J.-S. |
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Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells |
| Th1细胞是富含髓系细胞的血管周围激活生态位的关键组织者。 |
Bala, N. |
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Th1 cells are critical tissue organizers of myeloid-rich perivascular activation niches. |
| DOA/CLK2磷酸化Fl(2)d/WTAP以增强m6A mRNA甲基转移酶复合物的活性 |
McQuarrie, D. W. |
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DOA/CLK2 phosphorylates Fl(2)d/WTAP to enhance m6A mRNA methyltransferase complex activity |
| 跨父系环境和遗传背景的代际遗传的胚胎特征 |
Dura, M. |
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N/A |
Embryonic Signatures of Intergenerational Inheritance across Paternal Environments and Genetic Backgrounds |
| TonB依赖受体和氧化酶在铜抗性中的作用，该抗性与铁依赖性相关，在弯曲芽孢杆菌中 |
Cherry, P. |
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N/A |
Role of a TonB-dependent receptor and an oxygenase in iron-dependent copper resistance in Caulobacter crescentus |
| 通过片段重复实现的可进化性遵循物种特异性动力学 |
Islam, S. |
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Evolvability through segmental duplication follows species-specific dynamics |
| 通过转录激活在哺乳动物生殖细胞中启动基因启动子处的表观遗传景观 |
Li, P. |
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N/A |
Priming Epigenetic Landscape at Gene Promoters through Transcriptional Activation in Mammalian Germ Cells |
| 逐步破坏大肠杆菌RNA聚合酶-{lambda}R启动子接触和转录起始中的气泡塌陷的证据 |
Rector, M. J. |
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Evidence for Stepwise Disruption of E. coli RNA Polymerase-{lambda}R Promoter Contacts and Bubble Collapse in Transcription Initiation |
| 使用RAG的大型语言模型在自动标注表型描述方面的有效性 |
Kainer, D. |
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The effectiveness of Large Language Models with RAG for auto-annotating phenotype descriptions |
| 临床实践中的生物信息学建议 |
Lavrichenko, K. |
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N/A |
Recommendations for Bioinformatics in Clinical Practice |
| CHARMER：检测和协调跨组织和Hi-C协议的高置信度染色质相互作用 |
Cole, S. |
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N/A |
CHARMER: detecting and harmonizing high-confidence chromatin interactions across tissues and Hi-C protocols |
| Sirt5通过抑制ANT2的乳酸化来保护心脏功能免受缺血-再灌注损伤。 |
Zhang, L. |
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Sirt5 preserves cardiac function in ischemia-reperfusion injury by inhibiting ANT2 lactylation |
| 腿部固定及随后的恢复期抗阻训练对年轻健康成年人骨骼肌血管生成相关标志物的影响，与先前的抗阻训练经验无关。 |
McIntosh, M. C. |
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Leg immobilization and subsequent recovery resistance training affect skeletal muscle angiogenesis related markers in young healthy adults regardless of prior resistance training experience |
| 弥合巴西生物科学家Python培训差距：改进与挑战 |
Crestana, G. S. |
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Bridging the Python Training Gap for Bioscientists in Brazil: Improvements and Challenges |
| 单脉冲电刺激人脑的细胞类型特异性反应 |
Cowan, R. L. |
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N/A |
Cell-type specific responses to single-pulse electrical stimulation of the human brain |
| 离线5Hz-rTUS诱发皮层脊髓兴奋性双盲重复实验失败 |
Fong, P.-Y. |
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N/A |
Failed Double-Blind Replication of Offline 5Hz-rTUS-Induced Corticospinal Excitability |
| 通过静息脑熵（BEN）揭示了鼻内催产素给药的年龄依赖性效应。 |
Song, D. |
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N/A |
Age-dependent effects of intranasal oxytocin administration were revealed by resting brain entropy (BEN) |
| 铜绿假单胞菌介导的心脏功能障碍是由感染期间释放的胞外囊泡驱动的。 |
Rajaram, M. V. S. |
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N/A |
Pseudomonas aeruginosa-mediated cardiac dysfunction is driven by extracellular vesicles released during infection |
| 聚磷酸盐积累的贝氏硫细菌垫的非凡生理特征表明，磷酸盐缓冲在海洋沉积物中起着关键作用。 |
Iakovchuk, N. |
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N/A |
Extraordinary physiology of polyphosphate-accumulating Beggiatoa mats suggests a key role for phosphate buffering in marine sediments |
| 组蛋白伴侣Spt6通过其保守的N端结构域控制染色质结构 |
Warner, J. L. |
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N/A |
The histone chaperone Spt6 controls chromatin structure through its conserved N-terminal domain |
| 一个用于绘制生物多样性、气候和可持续发展关键生命支持区（ELSAs）的操作框架 |
Venter, O. |
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N/A |
An operational framework to map Essential Life Support Areas (ELSAs) for biodiversity, climate, and sustainable development |
| 使用总蛋白方法对保留和降低射血分数的心力衰竭患者进行AI驱动的分类 |
Lenzi, A. |
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N/A |
AI-driven Classification of Heart Failure Preserved and Reduced Ejection Fraction Patients Using the Total Protein Approach |
| Bwa，一种碱性神经酰胺酶-ACER2的直系同源物，通过促炎细胞因子信号传导促进果蝇肠道干细胞增殖。 |
Rahman, M. M. |
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N/A |
Bwa, an ortholog of alkaline ceramidase-ACER2, promotes intestinal stem cell proliferation through pro-inflammatory cytokine signaling in Drosophila melanogaster |
| 肾足细胞的线粒体呼吸能力较高，且随年龄变化，并具有性别二态性。 |
Campbell, M. D. |
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N/A |
Mitochondrial respiratory capacity in kidney podocytes is high, age-dependent, and sexually dimorphic. |
| 探讨癌症患者对微生物组工程技术态度的研究 |
Owen, K. A. |
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N/A |
Engaging cancer patients on their attitudes towards microbiome engineering technologies |
| 侧化的记忆网络解释了昆虫导航中使用的高阶视觉特征 |
Filippi, G. |
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N/A |
Lateralised memory networks explain the use of higher-order visual features in navigating insects |
| 增强的Notch依赖性胶质生成和延迟的生理成熟是Lowe综合征中神经发育缺陷的基础 |
Sharma, Y. |
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N/A |
Enhanced Notch dependent gliogenesis and delayed physiological maturation underlie neurodevelopmental defects in Lowe syndrome |
| 细胞和髓鞘构筑图谱指导下的灰质和白质结构特性的耦合老化 |
Hoagey, D. A. |
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N/A |
Coupled aging of cyto- and myeloarchitectonic atlas-informed gray and white matter structural properties |
| 跨参考框架的多感官整合与加法前馈网络 |
Farahmandi, A. |
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N/A |
Multisensory integration across reference frames with additive feed-forward networks |
| 在狼疮性肾炎中，纤维化区域的炎症先于肾功能的丧失。 |
Malvica, S. |
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N/A |
Inflammation in Areas of Fibrosis Precedes Loss of Kidney Function in Lupus Nephritis |
| 欧洲受保护地区面临气候变化的加速暴露 |
Cimatti, M. |
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N/A |
The accelerating exposure of European protected areas to climate change |
| 婴儿代谢的动态全身模型 |
Zaunseder, E. |
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N/A |
Dynamic whole-body models for infant metabolism |
| 有额颞叶痴呆家族史的无症状个体尿液蛋白质的变化 |
Su, Y. |
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N/A |
Changes in urinary proteins of unaffected individuals with a family history of frontotemporal dementia |
| 谱系特异性性状变异导致入侵性多宿主野生动物寄生虫中广泛存在同时共存和竞争排斥动态 |
Garner, T. W. |
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N/A |
Lineage-specific trait variation generates widespread, contemporaneous coexistence and competitive exclusion dynamics in an invasive, multihost wildlife parasite |
| 汉密尔顿法则的一般版本 |
van Veelen, M. |
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N/A |
The general version of Hamilton's rule |
| 使用边缘计算的玻璃体视网膜手术术中增强现实 |
Ye, R. Z. |
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N/A |
Intraoperative Augmented Reality for Vitreoretinal Surgery using Edge Computing |
| 通过ROCK抑制在蛋白酶可降解水凝胶中促进人唾液腺干细胞/祖细胞的极化和分化 |
Metkari, A. |
PDF |
N/A |
Promoting Polarization and Differentiation of Primary Human Salivary Gland Stem/Progenitor Cells in Protease-Degradable Hydrogels via ROCK Inhibition |
| iSIM-sigma：分子相似性高效标准差计算 |
Perez, K. L. |
PDF |
N/A |
iSIM-sigma: efficient standard deviation calculation for molecular similarity |
| SPACE：STRING蛋白质作为互补嵌入 |
Hu, D. |
PDF |
N/A |
SPACE: STRING proteins as complementary embeddings |
| DockFormer：利用成对Transformer高效预测多模态受体-配体相互作用 |
Shor, B. |
PDF |
N/A |
DockFormer: Efficient Multi-Modal Receptor-Ligand Interaction Prediction using Pair Transformer |
| 利用独特性：在弹性奠基图上的种子-链-延伸对齐 |
Rizzo, N. |
PDF |
N/A |
Exploiting uniqueness: seed-chain-extend alignment on elastic founder graphs |
| DyNDG：基于时间序列动态网络整合差异基因识别白血病相关基因 |
A, J. |
PDF |
N/A |
DyNDG: Identifying Leukemia-Related Genes based on the Time-Series Dynamical Network by Integrating Differential Genes |
| LRRC8A:D体积调节阴离子通道的组装与脂质调控 |
Lurie, A. |
PDF |
N/A |
Assembly and lipid-gating of LRRC8A:D volume-regulated anion channels |
| 利用实验血管数据进行高分辨率脑肿瘤模拟 |
Behle, E. |
PDF |
N/A |
Leveraging Experimental Vasculature Data for High Resolution Brain Tumor Simulations |
| 黑色素瘤患者前哨淋巴结中的免疫组织对远处转移具有预后意义 |
Amitay, Y. |
PDF |
N/A |
Immune organization in sentinel lymph nodes of melanoma patients is prognostic of distant metastases |
| 重复给予药用级中链甘油三酯（一种常见的药理学辅料），通过腹腔注射而非口服途径在小鼠中表现出剂量依赖性毒性。 |
Adler-Wachter, M. |
PDF |
N/A |
Repeated administration of pharmaceutical-grade medium chain triglycerides, a common pharmacologic excipient, confers dose-dependent toxicity by the intraperitoneal but not oral route in mice |
| 识别新型药物相互作用：迈向女性生殖健康精准医学 |
Garcia-Acero, P. |
PDF |
N/A |
Identification of novel drug-drug interactions: towards precision medicine in women's reproductive health |
| 比较转录组学分析揭示了由Pantoea agglomerans pv. betae的III型效应子操控的候选基因，这些基因导致了甜菜根瘤的形成。 |
Gupta, P. |
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N/A |
Comparative transcriptomic profile reveals candidate genes manipulated by type III effectors of Pantoea agglomerans pv. betae leading to gall formation in beet |
| 蒸腾作用洞察：通过高级建模估算蒸腾作用 |
Friedman, S. |
PDF |
N/A |
Transpiration Insights: Estimating Transpiration Through Advanced Modeling |
| 评估法国本土人口暴露于农药施用的程度，采用高分辨率的农药使用强度地图 |
Nowak, B. |
PDF |
N/A |
Assessment of population exposure to pesticide applications with a high-resolution map of pesticide use intensity for mainland France |
| cpTatC蛋白的N端结构域与叶绿体TAT转运中的前体成熟结构域相互作用 |
Maddethalawe, T. |
PDF |
N/A |
The N-terminal Domain of cpTatC Protein Interacts with the Precursor Mature Domain in Chloroplast TAT Translocation |
| 海洋硅藻三角褐指藻（Phaeodactylum tricornutum）对生长素（auxin）的生理、转录组和代谢组响应 |
Chen, Y.-T. |
PDF |
N/A |
Physiological, transcriptomic and metabolomic responses of the marine diatom Phaeodactylum tricornutum to auxin |
| 完整的菠菜叶绿体中类囊体膜的分子结构 |
Wietrzynski, W. |
PDF |
N/A |
Molecular architecture of thylakoid membranes within intact spinach chloroplasts |
| OsbHLH089和OsbHLH094通过调节OsSLR1水平来维持水稻的雄性生殖适应性 |
Fernandes, T. |
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N/A |
OsbHLH089 and OsbHLH094 Modulate OsSLR1 Levels to Maintain Male Reproductive Fitness in Rice |
| 使用Microsoft Sway作为药剂学实验课程中生成数据的存储库：一项关于外用制剂特性表征的案例研究 |
Chen, Q. |
PDF |
N/A |
Employing Microsoft Sway as a Repository for Data Generated in Pharmaceutics Experimental Courses: A Case study on Topical Formulation Characterization |
| 预处理脂肪间充质干细胞衍生的外泌体对贝赫切特葡萄膜炎免疫调节的影响 |
Gozel, M. |
PDF |
N/A |
Effects of Primed Adipose Mesenchymal Stem Cell-Derived Exosomes on Immunomodulation in Behcet Uveitis |
| 在人类细胞中表达重组人谷氨酰化TTLLs会导致不同的微管谷氨酰化模式，其中只有TTLL6会破坏微管动力学。 |
Al Kabbani, M. A. |
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N/A |
Expression of recombinant human glutamylating TTLLs in human cells leads to differential tubulin glutamylation patterns, with only TTLL6 disrupting microtubule dynamics |
| 使用新型造影剂对髓核进行高分辨率三维显微CT成像 |
Buckles, M. M. |
PDF |
N/A |
High-resolution 3-dimensional micro-CT imaging of the nucleus pulposus using a novel contrast agent |
| 亚热带树木生物多样性实验中，物种内和个体内的性状变异性随树种丰富度的增加而降低。 |
Castro Sanchez-Bermejo, P. |
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N/A |
Intraspecific and intraindividual trait variability decrease with tree species richness in a subtropical tree biodiversity experiment |
| 沿海盐沼滨螺Littoraria irrorata的生态关联：现场和实验室证据表明其对植被栖息地的偏好 |
Klinges, D. H. |
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N/A |
Ecological associations of the coastal marsh periwinkle snail Littoraria irrorata: field and laboratory evidence of vegetation habitat preferences |
| 多物种生态动力学中结构化与随机相互作用的相互作用 |
Giral Martinez, J. |
PDF |
N/A |
Interplay of structured and random interactions in many-species ecological dynamics |
| 海拔和海洋屏障塑造了新西兰卡波卡波瓦伊（Uropetala）蜻蜓的分布、扩散和多样性 |
Tolman, E. R. |
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N/A |
Elevational and Oceanic Barriers Shape the Distribution, Dispersal and Diversity of Aotearoa's Kapokapowai (Uropetala) Dragonflies |
| 解锁两栖植物适应的秘密：RNA修饰的作用 |
Mazdziarz, M. A. |
PDF |
N/A |
Unlocking the Secrets of Amphibious Plant Adaptation: The Role of RNA Modifications |
| 真菌GPCR基因家族的鉴定与分类 |
LIU, Z. |
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N/A |
Identification and Classification of Fungal GPCR Gene Families |
| 基因组语言模型的局限性与增强：动态选择方法 |
Qiu, S. |
PDF |
N/A |
Limitations and Enhancements in Genomic Language Models: Dynamic Selection Approach |
| 氯化物遗传编码指示剂的定向进化 |
Peng, W. |
PDF |
N/A |
Directed Evolution of a Genetically Encoded Indicator for Chloride |
| 脂肪组织的机械各向异性调节卵巢癌的侵袭 |
Gonzalez-Molina, J. |
PDF |
N/A |
The mechanical anisotropy of adipose tissues regulates ovarian cancer invasion |
| 基于强化学习的电机脑机接口软件模拟器 |
Liang, K.-F. |
PDF |
N/A |
A reinforcement learning based software simulator for motor brain-computer interfaces |
| VaxLLM：利用微调的大型语言模型进行布鲁氏菌疫苗的自动化标注 |
Li, X. |
PDF |
N/A |
VaxLLM: Leveraging Fine-tuned Large Language Model for automated annotation of Brucella Vaccines |
| 利用人类泛蛋白组提升蛋白质组学和元蛋白质组学中的肽段和蛋白质鉴定能力 |
Canderan, J. |
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N/A |
Leveraging the Human Panproteome to Enhance Peptide and Protein Identification in Proteomics and Metaproteomics |
| 通过计算机模拟发现大肠杆菌中芳香族氨基酸生产的靶点 |
Fonseca, A. P. |
PDF |
N/A |
In silico target discovery for aromatic amino acid production in Escherichia coli |
| OrthologAL：一个用于非人类临床前高维基因表达数据质量感知人源化的Shiny应用程序 |
CHOWDARY, R. |
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N/A |
OrthologAL: A Shiny application for quality-aware humanization of non-human pre-clinical high-dimensional gene expression data |
| 使用二甲双胍针对更年期过渡期可改善乳腺癌预后，但停药对代谢健康有不利影响：来自绝经后乳腺癌的临床前模型研究结果。 |
Corleto, K. A. |
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N/A |
Targeting the menopause transition with metformin improves breast cancer outcomes, but discontinuation has deleterious effects on metabolic health: Findings from a preclinical model of postmenopausal breast cancer. |
| 在癌症中，CD47相对于CD24在巨噬细胞免疫检查点中占主导地位。 |
Allen, J. |
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N/A |
CD47 predominates over CD24 as a macrophage immune checkpoint in cancer. |
| 逐步组装冠爬行动物解剖结构：晚古生代新双孔类旁系群阐明 |
Jenkins, X. |
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N/A |
Stepwise Assembly Of Crown Reptile Anatomy Clarified By Late Paleozoic Outgroups Of Neodiapsida |
| 内皮细胞中的RIPK3可减轻缺血-再灌注损伤中的器官特异性炎症和血管通透性 |
Johnson, C. F. |
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N/A |
Endothelial RIPK3 minimizes organotypic inflammation and vascular permeability in ischemia-reperfusion injury |
| 植物易感性的组织非依赖性：通过根和叶对系统性植物病原菌拉氏假单胞菌在茄子和番茄幼苗中的比较致病性研究 |
Bhuyan, S. |
PDF |
N/A |
Tissue-independent nature of plant susceptibility: a comparative pathogenicity study of the systemic phytopathogen Ralstonia pseudosolanacearum in eggplant and tomato seedlings through root and leaf |
| 一种基于质量源于设计（QbD）的策略，用于开发同时负载姜黄素和siRNA的脂质体复合物，以对抗与骨关节炎相关的炎症和氧化应激。 |
Ranamalla, S. R. |
PDF |
N/A |
A QbD strategy to develop curcumin and siRNA co-loaded lipoplexes to combat osteoarthritis-related inflammation and oxidative stress |
| 溶酶体钙信号通过钙刺激的腺苷酸环化酶1和8介导急性α-肾上腺素能反应 |
Akerman, E. |
PDF |
N/A |
Lysosomal calcium signalling contributes to the acute α-adrenergic response via calcium-stimulated adenylyl cyclase 1 and 8 |
| 心房心肌细胞中的心房颗粒作为酸性钙储存库 |
Akerman, E. |
PDF |
N/A |
Atrial Granules in Atrial Cardiomyocytes as Acidic Calcium Stores |
| 鉴定调控启动子序列在蒺藜苜蓿（Medicago truncatula）根瘤衰老初期指导MtCP6转录的作用。 |
Yang, L. |
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N/A |
Identification of regulatory promoter sequences directing MtCP6 transcription at the onset of nodule senescence in Medicago truncatula. |
| 人工智能对蛋白质结构的建模能否区分传感器和辅助NLR免疫受体？ |
Toghani, A. |
PDF |
N/A |
Can AI modelling of protein structures distinguish between sensor and helper NLR immune receptors? |
| 单细胞代谢振荡普遍存在，可能有助于缓解蛋白质组约束。 |
Wongprommoon, A. |
PDF |
N/A |
Single-cell metabolic oscillations are pervasive and may alleviate a proteome constraint |
| 额极皮层刺激导致反事实加工的长期中断：来自局部场电位变化的见解 |
Ainsworth, M. |
PDF |
N/A |
Frontopolar cortex stimulation induces prolonged disruption to counterfactual processing: insights from altered local field potentials |
| 阅读习得促使语言跨模态在左腹侧枕颞皮层中的融合 |
Debska, A. |
PDF |
N/A |
Reading Acquisition Drives Linguistic Cross-Modal Convergence in The Left Ventral Occipitotemporal Cortex |
| 在成年早产小鼠的感觉皮层和前额叶皮层中，对行为显著线索的类似青少年的处理方式 |
McCoy, E. |
PDF |
N/A |
Adolescent-like Processing of Behaviorally Salient Cues in Sensory and Prefrontal Cortices of Adult Preterm-Born Mice |
| 人类视觉皮层中概念流形的几何结构变异 |
St-Yves, G. |
PDF |
N/A |
Variation in the geometry of concept manifolds acrosshuman visual cortex |
| CalliCog：一个用于自由行为非人灵长类的开源认知神经科学工具包 |
Scott, J. |
PDF |
N/A |
CalliCog: an open-source cognitive neuroscience toolkit for freely behaving nonhuman primates |
| 量化存储在突触连接中的信息，而非神经网络的放电模式 |
Fan, X. |
PDF |
N/A |
Quantifying information stored in synaptic connections rather than in firing patterns of neural networks |
| 通过内部感觉预测的持续学习，建模对改变的感觉反馈的语音适应 |
Elie, B. |
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N/A |
Modeling speech adaptation to altered sensory feedback through continuous learning of internal sensory predictions |
| 气质特质的神经行为相关性：基于气质与性格量表及功能性磁共振成像选择任务的见解 |
Abbasi Sisara, M. |
PDF |
N/A |
Behavioral and Neural Correlates of Temperament Traits: Insights from Temperament and Character Inventory and fMRI-Based Choice Tasks |
| 塑造发育中的小人：感觉重映射中剥夺与补偿行为的作用 |
Tucciarelli, R. |
PDF |
N/A |
Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping |
| 皮层组装体支持快速放电的人类PVALB+皮层中间神经元的发育，并揭示了与精神分裂症相关的缺陷。 |
Walsh, R. M. |
PDF |
N/A |
Cortical assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects |
| 元认知内省改变了决策前神经证据积累的动力学 |
Dou, W. |
PDF |
N/A |
Metacognitive Introspection Alters the Dynamics of Pre-Decisional Neural Evidence Accumulation |
| 在自然视觉中，观察到的动作的行为相关特征在皮层表征的几何结构中占据主导地位。 |
Han, J. |
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N/A |
Behaviorally-relevant features of observed actions dominate cortical representational geometry in natural vision |
| 成人嗅球解剖、组织学及超微结构：血管及淀粉样小体评估 |
Raspeno-Garcia, J. |
PDF |
N/A |
Anatomy, histology and ultrastructure of the adult human olfactory peduncle: blood vessel and corpora amylacea assessment |
| 你的记忆宫殿有多坚固？可靠的房间表征预示着随后放置物品的恢复 |
Masis-Obando, R. |
PDF |
N/A |
How sturdy is your memory palace? Reliable room representations predict subsequent reinstatement of placed objects |
| 神经遗传学证据表明，Lgr3阳性生长控制中间神经元在果蝇中表现出振荡行为 |
Zanini, R. |
PDF |
N/A |
Neurogenetic evidence for oscillatory behavior of Lgr3-positive growth control interneurons in Drosophila |
| 跨感觉切换的神经机制：延迟感觉处理和增加认知努力的证据 |
Vanneau, T. |
PDF |
N/A |
Neural Mechanisms of Intersensory Switching: Evidence for Delayed Sensory Processing and Increased Cognitive Effort |
| 在个体水平的功能梯度分析中，普罗克鲁斯特斯对齐法 |
Sasse, L. |
PDF |
N/A |
Procrustes Alignment in Individual-level Analyses of Functional Gradients |
| 纵向结构磁共振脑影像配准刚体配准算法比较研究 |
Rezaee Jouryabi, Y. |
PDF |
N/A |
A comparative study of rigid-body registration algorithms for the alignment of longitudinal structural MRI of the brain |
| APP NL-G-F小鼠内侧内嗅皮层中的空间编码受损和神经元过度活跃 |
Rodriguez, G. A. |
PDF |
N/A |
Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of APP NL-G-F mice |
| 嗜酸性粒细胞促进单核细胞向巨噬细胞分化及抗菌免疫 |
Wilson, G. J. |
PDF |
N/A |
Eosinophils promote monocyte to macrophage differentiation and anti-bacterial immunity |
| 中性粒细胞趋化因子CXCL5在急性肺损伤中诱导肺屏障通透性 |
Berger, S. |
PDF |
N/A |
Neutrophil-chemoattractant CXCL5 induces lung barrier permeability in acute lung injury |
| 增强的艰难梭菌TcdB疫苗与合成双TLR配体佐剂联合使用的免疫原性。 |
Naz, F. |
PDF |
N/A |
Enhanced immunogenicity of a Clostridioides difficile TcdB vaccine adjuvanted with a synthetic dual-TLR ligand adjuvant. |
| MCUB依赖性抑制线粒体钙摄取的机制 |
Rai, N. K. |
PDF |
N/A |
Mechanism of MCUB-dependent inhibition of mitochondrial calcium uptake |
| 环节动物视角下FGF信号在尾部再生中的作用 |
Shalaeva, A. Y. |
PDF |
N/A |
Annelid perspectives into the role of FGF signaling in caudal regeneration |
| 整合体复合物通过全局调控转录延伸，防止神经元过早分化。 |
Somsen, H. B. |
PDF |
N/A |
The Integrator complex prevents premature neuronal differentiation through global control of transcription elongation. |
| 性染色体塑造了植入前小鼠胚胎的转录景观 |
Snell, D. M. |
PDF |
N/A |
Sex chromosomes shape the transcriptional landscape of the preimplantation mouseembryo |
| 尽管与膜翅目昆虫存在进化上的相似性，但从蟑螂到白蚁的社会性进化过程中，监管复杂性有所降低。 |
Jones, A. |
PDF |
N/A |
Reduced regulatory complexity associated with the evolutionary transition to sociality from cockroaches to termites despite evolutionary parallels with Hymenoptera |
| 翻译上游区域的快速降解表明翻译起始过程效率低下。 |
Tress, M. L. |
PDF |
N/A |
The rapid degradation of translated upstream regions points to an inefficient translation initiation process |
| 颜色变化作为免疫能力权衡假说预测的权衡的替代解决方案 |
Sacchi, R. |
PDF |
N/A |
Colour morphs as alternative solutions to the trade-off predicted by the Immuno-Competence Handicap Hypothesis |
| 秀丽隐杆线虫可靠的气味感知与可变的联想学习 |
Tasnim, S. |
PDF |
N/A |
Reliable odorant sensing but variable associative learning in C. elegans |
| 量子关联在工程化磁敏荧光蛋白中的应用使活细胞内实现多模态传感成为可能 |
Abrahams, G. J. |
PDF |
N/A |
Quantum Correlations in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells |
| 从头组装的数据库使得无需事先了解群落组成，即可对微生物群进行基于物种特异性蛋白质的稳定同位素探针研究。 |
Klaes, S. |
PDF |
N/A |
De novo assembled databases enable species-specific protein-based stable isotope probing of microbiomes without prior knowledge of the community composition |
| 深度学习揭示了对抗肺炎克雷伯菌的潜在抗生素耐药药物 |
Lin, P. |
PDF |
N/A |
Deep Learning Unravels Potential Antibiotic-Resistance Drugs against Klebsiella Pneumoniae |
| 易患炎症性肠病会促进小鼠模型中ATF6驱动的结肠癌发生侵袭性癌变。 |
Kövilein, J. |
PDF |
N/A |
Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer |
| 利用机器学习识别特发性肺纤维化与肺鳞状细胞癌之间分子网络的差异 |
Nojima, Y. |
PDF |
N/A |
Identification of the differences in molecular networks between idiopathic pulmonaryfibrosis and lung squamous cell carcinoma using machine learning |
| 皮质神经活动在应对机械性扰动时的反应：手偏好和使用手的影响 |
Hooks, K. |
PDF |
N/A |
Cortical neural activity during responses to mechanical perturbation: Effects of hand preference and hand used |
| 在慢性暴饮酒精后的戒断和长期戒断期间，小胶质细胞促进神经退行性和过度兴奋。 |
McNair, E. |
PDF |
N/A |
Microglia promote neurodegeneration and hyperkatifeia during withdrawal and prolonged abstinence from chronic binge alcohol |
| 一种用于θ节律采样的通用过程，可以对环境信息或内部存储信息进行采样。 |
Fiebelkorn, I. C. |
PDF |
N/A |
A domain-general process for theta-rhythmic sampling of either environmental information or internally stored information |
| 眶额皮层和前扣带皮层亚区在决策与脑-体调节中的功能二分法 |
Papageorgiou, G. K. |
PDF |
N/A |
Functional Dichotomy of Orbitofrontal Cortex and Anterior Cingulate Cortex Subregions in Decision-Making and Brain-Body Regulation |
| 处理双关幽默中的负面词汇：混合情感的动态表现，融合了娱乐性与消极性 |
Sun, Y. |
PDF |
N/A |
Processing negative words in pun-humor: dynamic representation of mixed feelings blending amusement and negativity |
| 通过PARG99选择性抑制细胞质中的PARylation：一种针对FUS相关神经退行性变的靶向方法 |
Kodavati, M. |
PDF |
N/A |
Selective Inhibition of Cytosolic PARylation via PARG99: A Targeted Approach for Mitigating FUS-associated Neurodegeneration |
| 通过体内邻近标记技术揭示视网膜神经元中的电突触蛋白质组 |
Tetenborg, S. |
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Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling |
| 学习和可塑性信号诱导突触线粒体中的极化ATP合酶 |
Hu, Y. |
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Polarized ATP synthase in synaptic mitochondria induced by learning and plasticity signals |
| 耳念珠菌氧化应激反应相关过氧化物酶Tsa1b作为一种毒力因子，促进感染。 |
Areitio, M. |
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The oxidative stress response-related peroxiredoxin Tsa1b of Candida auris functions as a virulence factor that promotes infection |
| 鉴定出EcpK，一种对粘细菌Myxococcus xanthus中胞外多糖生物合成至关重要的细菌酪氨酸假激酶 |
Bloecher, L. |
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Identification of EcpK, a bacterial tyrosine pseudokinase important for exopolysaccharide biosynthesis in Myxococcus xanthus |
| 多个冗余的羧酸转运蛋白支持恶性疟原虫线粒体代谢 |
Prigge, S. T. |
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MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN PLASMODIUM FALCIPARUM |
| 当代H3N2病毒受体结合域中的上位性，这些病毒已回复为结合唾液酸化二乳糖胺重复序列 |
Liang, R. |
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Epistasis in the receptor binding domain of contemporary H3N2 viruses that reverted to bind sialylated diLacNAc repeats |
| 细菌RNA中假尿苷的定量图谱 |
Sharma, S. |
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Quantitative mapping of pseudouridines in bacteria RNA |
| MdfA和ClpCP介导的发育调控蛋白水解在枯草芽孢杆菌孢子形成过程中的代谢分化中起作用 |
Riley, E. P. |
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Developmentally-regulated proteolysis by MdfA and ClpCP mediates metabolic differentiation during Bacillus subtilis sporulation |
| 肠球菌细胞壁的重塑通过释放肠球菌多糖抗原（EPA）来支撑其致病性。 |
Smith, R. E. |
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Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA) |
| 生长速率调控酿酒酵母中RNA聚合酶II的转录延伸 |
Garrido-Godino, A. I. |
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Growth rate regulates RNA polymerase II transcription elongation in Saccharomyces cerevisiae |
| COVID-19疾病严重程度与T细胞受体库之间的关联 |
Chen, X. |
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Association between COVID-19 Disease Severity and T Cell Receptor Repertoire |
| 编程群体组成和多细胞形态的综合比率计算 |
An, B. |
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Synthetic ratio computation for programming population composition and multicellular morphology |
| 高分辨率分析揭示了转基因的转录和翻译调控的耦合机制。 |
Peterman, E. L. |
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High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes |
| 基于大肠杆菌的无细胞系统中苹果酸的碳节约型生物生产 |
Cardiff, R. |
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Carbon-conserving Bioproduction of Malate in an E. coli-based Cell-Free System |
| 在日本发现异源四倍体杂种物种黑曲霉 |
Shibata, S. |
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Discovery of allodiploid hybrid species Aspergillus latus in Japan |
| 罗非鱼湖病毒核蛋白与RNA结合的结构 |
Arragain, B. |
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Structure of the Tilapia lake virus nucleoprotein bound to RNA |
| 果糖诱发代谢功能障碍的倾向取决于基线饮食、饮食暴露的时间长度以及小鼠的性别。 |
Fadhul, T. |
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The propensity of fructose to induce metabolic dysfunction is dependent on the baseline diet, length of the dietary exposure, and sex of the mice. |
| 拟南芥PRMT5通过缓冲供体剪接位点的遗传变异，调节前体mRNA剪接和发育 |
Beckel, M. S. |
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Arabidopsis PRMT5 Buffers Pre-mRNA Splicing and Development Against Genetic Variation in Donor Splice Sites |
| 从700,000生物银行参与者中探究DNA重复扩展的原因和后果 |
Hujoel, M. L. A. |
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Insights into the causes and consequences of DNA repeat expansions from 700,000 biobank participants |
| 启动子与关键的压力相关转录因子结合，以调控压力应答基因簇。 |
Malfait, J. |
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Epromoters bind key stress-related transcription factors to regulate clusters of stress response genes |