| 从局部相互作用和光滑梯度中涌现出强大的全局模块 |
Khona, M. |
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N/A |
Emergence of robust global modules from local interactions and smooth gradients |
| KPop：通过序列嵌入实现微生物基因组的准确且可扩展的比较分析 |
Didelot, X. |
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N/A |
KPop: Accurate and scalable comparative analysis of microbial genomes by sequence embeddings |
| 在未受干扰的DNA复制过程中，ATR的激活受到VCP/p97的限制，这是通过从染色质中提取DNA聚合酶α/引发酶实现的。 |
Rodriguez-Acebes, S. |
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N/A |
The activation of ATR during unperturbed DNA replication is restricted by VCP/p97 through the extraction of DNA polymerase α/Primase from chromatin |
| 拟南芥LSM7对于生长素介导的SAUR基因调控和热形态发生是必不可少的。 |
Nardeli, S. M. |
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N/A |
Arabidopsis thaliana LSM7 is essential for auxin-mediated regulation of SAUR genes and thermomorphogenesis |
| SMARCAD1和TOPBP1在从2C样状态向多能状态过渡时，对异染色质的维持起到了作用。 |
Sebastian-Perez, R. |
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N/A |
SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state |
| 全脑因果发现使用fMRI |
Arab, F. |
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N/A |
Whole-Brain Causal Discovery Using fMRI |
| 尼古丁与安慰剂口香糖对疼痛敏感性的影响及其对峰值α频率的介导作用 |
Millard, S. K. |
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N/A |
Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency |
| 外侧嗅周皮质通过整合视觉空间序列来支持物体感知。 |
Bonnen, T. |
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N/A |
Perirhinal cortex supports object perception by integrating over visuospatial sequences |
| RNA G-四链体在衰老和阿尔茨海默病中的新角色 |
Kallweit, L. |
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N/A |
A New Role for RNA G-quadruplexes in Aging and Alzheimer's Disease |
| 发声过程中对听觉反馈错误的意识和无意识感知：行为功能与事件相关电位相关性 |
Suchy, D. |
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N/A |
Conscious and unconscious perception of errors in auditory feedback during vocalization: Behavioral functions and event-related potential correlates |
| 母体蔗糖摄入改变了母亲、胎盘和胎儿的类固醇水平。 |
Seib, D. R. |
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N/A |
Maternal sucrose consumption alters steroid levels in the mother, placenta, and fetus |
| 海马体背腹轴上恐惧学习和恐惧表达的整合 |
Pompili, M. N. |
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N/A |
Integration of fear learning and fear expression across the dorsoventral axis of the hippocampus |
| 利用光遗传学技术绘制小鼠纹状体中与节律性相位相关的兴奋性图谱 |
Mohapatra, M. |
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N/A |
Optogenetic mapping of rhythmic phase-dependent excitability in the mouse striatum |
| 程序性细胞死亡与蚂蚁翅膀多态性的起源：对个体性重大进化转变的启示 |
Hanna, L. |
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N/A |
Programmed cell death and the origin of wing polyphenism in ants: implications for major evolutionary transitions in individuality |
| MixtureFinder：用于系统发育分析的DNA混合模型估计 |
Ren, H. |
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N/A |
MixtureFinder: Estimating DNA mixture models for phylogenetic analyses |
| VPS41的缺失会引发胰岛素储存的逐渐丧失以及β细胞身份的下调。 |
Yau, B. |
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N/A |
VPS41 deletion triggers progressive loss of insulin stores and downregulation of beta-cell identity |
| 肝脏特异性生存运动神经元（SMN）耗竭对中枢神经系统及外周组织病理学的影响 |
de Almeida, M. M. |
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N/A |
Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology |
| Cdbgtricks：更新压缩de Bruijn图的策略 |
Hannoush, K. |
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N/A |
Cdbgtricks: strategies to update a compacted de bruijn graph |
| 群体认同促进大脑整合以实现集体表现 |
Enhui, X. |
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N/A |
Group identification drives brain integration for collective performance |
| 超高剂量率氦离子束：在保持肿瘤控制的同时最小化脑组织损伤 |
Dokic, I. |
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N/A |
Ultra-High Dose Rate Helium Ion Beams: Minimizing Brain Tissue Damage while Preserving Tumor Control |
| 未被抑制的皮层抑制性神经元集合控制着远距离记忆的提取 |
Wang, S. |
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N/A |
Unsilenced inhibitory cortical ensemble gates remote memory retrieval |
| MLL4调控出生后腭部生长和中腭缝发育 |
Lee, J.-M. |
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N/A |
MLL4 regulates postnatal palate growth and midpalatal suture development |
| 一种基于脉冲依赖的突触神经网络片上学习算法 |
Stuck, M. |
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N/A |
A Burst-Dependent Algorithm for Neuromorphic On-Chip Learning of Spiking Neural Networks |
| 伏隔核中D1/D2中型多棘神经元在雄性东方田鼠配对结合形成中的不同作用 |
Zhang, L. |
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N/A |
Different Roles of D1/D2 Medium Spiny Neurons in the Nucleus Accumbens in Pair Bond Formation of Male Mandarin Voles |
| 铜绿假单胞菌中CsoR对趋化性和铜抗性的协同调控 |
He, M. |
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N/A |
Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida |
| 利用CRISPR富集的宏基因组方法增强废水样本中抗生素抗性基因的检测 |
Mao, Y. |
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N/A |
Enhanced detection for antibiotic resistance genes in wastewater samples using CRISPR-enriched metagenomic method |
| 磷酸化和去磷酸化在Rubisco活化酶调控中的作用 |
Bhatnagar, N. |
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N/A |
The role of phosphorylation and dephosphorylation in the regulation of Rubisco activase |
| 选择性自噬通过降解Su(var)2-10/PIAS来微调Stat92E活性，在果蝇神经胶质损伤信号传导过程中起作用。 |
Vincze, V. |
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N/A |
Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signalling in Drosophila |
| 广泛的行为指标与大脑微观结构之间的关联在自闭症谱系障碍（ASD）中普遍存在，这表明年龄可能介导了不同亚型的ASD。 |
Ressa, H. |
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N/A |
Widespread Associations between Behavioral Metrics and Brain Microstructure in ASD Suggest Age Mediates Subtypes of ASD |
| Megabouts：一种用于斑马鱼运动分析的灵活管道 |
Jouary, A. |
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N/A |
Megabouts: a flexible pipeline for zebrafish locomotion analysis |
| 雌性生殖系特异性蛋白Sakura与Otu相互作用，对生殖干细胞的更新、分化及卵子发生过程至关重要。 |
Azlan, A. |
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N/A |
Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis |
| 工作记忆从优先和非优先状态中提取的长期影响 |
Born, F. |
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N/A |
Long-Term Effects of Working Memory Retrieval From Prioritized and Deprioritized States |
| 弓形虫引发的侵袭孔 |
Kegawa, Y. |
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N/A |
The invasion pore induced by Toxoplasma gondii |
| 鸡盲肠微生物群落的代谢建模揭示了竞争与合作的格局 |
Utkina, I. |
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N/A |
Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation |
| 利用H2在Cupriavidus necator H16中生产木糖醇 |
Jämsä, T. |
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N/A |
H2-driven xylitol production in Cupriavidus necator H16 |
| 开发自主神经系统多尺度神经连接知识库 |
Imam, F. T. |
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N/A |
Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System |
| 核糖体生物合成超激活与ErbB信号传导介导的网络重塑导致对FGFR2抑制的适应性抗性 |
Zhang, T. |
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N/A |
Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition |
| 离子传感器与dSarm并行作用，促进神经退行性变 |
Avetisyan, A. |
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N/A |
An Ionic Sensor acts in Parallel to dSarm to Promote Neurodegeneration |
| 多尺度兴奋-抑制平衡动力学：整合代谢物动力学与时变执行网络 |
Saviola, F. |
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N/A |
Multiscale excitation-inhibition balance dynamics: integrating metabolite kinetics with time-varying executive networks |
| 核糖体丰度而非旁系同源基因组成对生殖系发育至关重要 |
Grobicki, K. Z. A. |
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N/A |
Ribosome abundance, not paralogue composition, is essential for germline development |
| 高分辨率成像图谱揭示了胰腺交感神经支配在糖尿病小鼠中的情境依赖性作用 |
Xu, Q. |
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N/A |
High-resolution imaging atlas reveals context-dependent role of pancreatic sympathetic innervation in diabetic mice |
| 靶向激活小胶质细胞PPARδ重编程免疫代谢并增强饮食诱导肥胖中的胰岛素敏感性。 |
Jiao, H. |
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N/A |
Targeted activation of microglial PPARdelta reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity. |
| 在问题解决过程中，眼睛和手的协同发音揭示了层次化的规划结构。 |
Eluchans, M. |
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N/A |
Eye and hand coarticulation during problem solving reveals hierarchically organized planning |
| Lewy-MSA混合折叠驱动独特的神经元α-突触核蛋白病理 |
Enomoto, M. |
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N/A |
Lewy-MSA hybrid fold drives distinct neuronal a-synuclein pathology |
| 将空间药物异质性与微生物生长动力学在理论和实验中联系起来 |
Hu, Z. |
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N/A |
Linking spatial drug heterogeneity to microbial growthdynamics in theory and experiment |
| 在胚胎关键时期，线粒体活性氧的保守和HIF1-α信号传导指导随后的神经系统发育 |
Sobrid-Camean, D. |
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N/A |
Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development |
| 人类平滑受体中胆固醇感知与转运的能量学 |
Bansal, P. D. |
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N/A |
Energetics of cholesterol perception and translocation in the human Smoothened receptor |
| 有家族性额颞叶痴呆病史的无症状个体尿蛋白的变化 |
Su, Y. |
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N/A |
Changes in urinary proteins of unaffected individuals with a family history of frontotemporal dementia |
| 塑造发育中的小人：剥夺和补偿行为在感觉重映射中的作用 |
Tucciarelli, R. |
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N/A |
Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping |
| 发现一种源自SARS-CoV2 S2蛋白的肽段，具有类似超抗原的T细胞刺激特性 |
Tu, T. H. |
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N/A |
The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells |
| 特定谱系驱动因子库将果蝇腹神经索中发育中的神经回路与行为联系起来。 |
Soffers, J. H. |
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N/A |
A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord. |
| 对一个由宏基因组组装的基因组进行比较基因组分析，揭示了Mucoromycotina细根内生菌根真菌中独特的共生特性 |
Cole, J. |
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N/A |
Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus |
| 基于人群的元蛋白质组学揭示了肠道微生物群与表型之间的功能关联 |
Liang, S. |
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N/A |
Population-based metaproteomics reveals functional associations between gut microbiota and phenotypes |
| 通过瞬时递送CRISPR表观基因组编辑器核糖核蛋白实现可编程的表观基因组编辑 |
Xu, D. |
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N/A |
Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins |
| 氨基酸酰基-RNA环化连接的立体选择性 |
Kim, S. |
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N/A |
Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation |
| 基因（组）重复对GPCR信号通路扩展和进化的影响 |
Barradas, A. |
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N/A |
Implications of gen(om)e duplications on the expansion and evolution of the GPCR signalling pathway |
| 特定阶段CAR介导的信号传导从诱导多能干细胞生成类似初始状态、TCR缺失的CAR T细胞 |
Yoo, S. P. |
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N/A |
Stage-specific CAR-mediated signaling generates naive-like, TCR-null CAR T cells from induced pluripotent stem cells |
| 聚集肠道：神经退行与细菌功能性淀粉样蛋白之间的联系 |
Wojciechowska, A. W. |
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N/A |
Aggregating gut: on the link between neurodegeneration and bacterial functional amyloids |
| SNMF：综合学习突变特征与预测DNA修复缺陷 |
Goossens, S. A. C. H. |
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N/A |
SNMF: Integrated Learning of Mutational Signatures and Prediction of DNA Repair Deficiencies |
| TCF3::HLF通过调控增强子-启动子网络并激活MEF2C，促进白血病中未成熟造血干细胞基因表达 |
Priebe, V. |
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N/A |
TCF3::HLF Orchestrates an Enhancer-Promoter Network with Activation of MEF2C to Promote Immature HSC gene Expression in Leukemia |
| 分析公开可用的转录组数据以识别与骨肉瘤转移相关的关键基因和通路 |
Horak, I. |
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N/A |
Analysis of publicly available transcriptomic data to identify key genes and pathways associated with osteosarcoma metastasis |
| Alk1在动脉内皮细胞中的缺失会导致鼻出血、脑微出血、动脉异常以及平滑肌覆盖缺陷。 |
Zhang, X. |
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N/A |
Arterial endothelial deletion of Alk1 causes epistaxis and cerebral microhemorrhage with aberrant arteries and defective smooth muscle coverage. |
| 大豆脉坏死病毒（SVNV）蛋白的特性分析：田间株系序列分析及不同细胞类型中定位模式的比较 |
Shehata, A. H. |
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N/A |
Characterization of Soybean Vein Necrosis Virus (SVNV) Proteins: Sequence Analysis of Field Strains and Comparison of Localization Patterns in Differing Cell Types |
| 感觉神经元中的Piezo2影响全身和脂肪组织的代谢 |
Passini, F. S. |
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N/A |
Piezo2 in sensory neurons influences systemic and adipose tissue metabolism |
| 蚕豆耐寒性的全基因组关联研究揭示了冷季豆科植物中的同源位点，并突出了相关的候选基因 |
Imbert, B. |
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N/A |
Genome-wide association study of frost tolerance in Vicia faba reveals syntenic loci in cool-season legumes and highlights relevant candidate genes |
| PIEZO1在完整细胞中的纳米结构和结构多样性 |
Verkest, C. |
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N/A |
Cluster nanoarchitecture and structural diversity of PIEZO1 in intact cells |
| 使用蛋白酶体靶向纳米体偶联物降解内在无序蛋白 |
Sun, X. |
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N/A |
Degradation of intrinsically disordered proteins using proteolysis targeting nanobody conjugate |
| 自我冷却的花朵：炎热地中海环境中夏季开花的蓟的热生态学 |
Herrera, C. M. |
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N/A |
Flowers that cool themselves: thermal ecology of summer-blooming thistles in hot Mediterranean environments |
| 珊瑚修复只有在当地人类压力水平较低时才可行 |
Brookson, C. B. |
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N/A |
Coral restoration is only practical when local human pressure levels are low |
| 鱼与熊掌不可兼得：在景观连通性恢复中权衡生态系统服务与生物多样性组合 |
Neyret, M. |
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N/A |
One cannot have it all: trading-off ecosystem services and biodiversity bundles in landscape connectivity restoration |
| 与太平洋西北地区土壤中种植的优质冬豌豆品种相关的细菌群落 |
Yurgel, S. |
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N/A |
Bacterial communities associated with food-quality winter pea cultivars grown in Pacific Northwest soils |
| 进化救援模型提供了推动癌细胞种群走向灭绝的策略。 |
Dabi, A. |
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N/A |
Evolutionary rescue model informs strategies for driving cancer cell populations to extinction |
| 更新后的参考基因组序列和注释揭示了基因的丢失和获得，这些变化是裸鼹鼠生物学特性的基础。 |
Sokolowski, D. J. |
PDF |
N/A |
An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology |
| siRNA途径对埃及伊蚊转座子表达的有限影响 |
Bergman, A. |
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N/A |
Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti |
| 关联分析揭示了在茄子驯化过程中，既有人为选择事件，也有环境选择事件。 |
Omondi, E. |
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N/A |
Association analyses reveal both anthropic and environmental selective events during eggplant domestication |
| 利用葡糖杆菌氧化菌对超镁铁质矿物的生物加速风化作用 |
Lee, J. J. |
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N/A |
Bio-Accelerated Weathering of Ultramafic Minerals with Gluconobacter oxydans |
| 长期肘部疼痛及重复经颅磁刺激对皮层抑制作用的影响：一项TMS-EEG研究 |
Chowdhury, N. |
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N/A |
The effect of prolonged elbow pain and rTMS on cortical inhibition: A TMS-EEG study |
| 鼠疫耶尔森菌的全球进化模式及其向非洲的传播 |
Mas Fiol, G. |
PDF |
N/A |
Global evolutionary patterns of Yersinia pestis and its spread into Africa |
| 宫颈阴道微生物特征可预测感染女性沙眼衣原体向生殖道上部的传播 |
Jeong, S. |
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N/A |
Cervicovaginal microbial features predicts Chlamydia trachomatis spread to the upper genital tract of infected women |
| 重复的香烟烟雾暴露会降低体外培养的人类肺成纤维细胞的增殖速率。 |
Cannard, E. C. |
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N/A |
Repeated cigarette smoke exposure attenuates the proliferation rate of primary human lung fibroblasts in vitro |
| 使用3D-NaissI方法揭示成年心脏组织的原生结构 |
PATALUCH, N. |
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N/A |
Unveiling the native architecture of adult cardiac tissue using the 3D-NaissI method |
| Rab2B促进伴侣蛋白介导的肌动蛋白折叠，并防止锥虫中的发育性转录重编程和静止 |
Li, F.-J. |
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N/A |
Rab2B promotes chaperonin-mediated actin folding and prevents developmental transcription reprogramming and quiescence in trypanosomes |
| 非肌肉型α-肌动蛋白是心肌Z盘的内在组成部分，参与调节肌节周转、收缩力和心脏重塑过程。 |
Hayes, J. B. |
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N/A |
A non-muscle α-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling |
| FIC-1介导的AMP化作用丧失会激活UPRER，并上调细胞质HSP70分子伴侣，以抑制多聚谷氨酰胺毒性。 |
Van Pelt, K. M. |
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N/A |
Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity |
| 喜马拉雅全基因组序列提供了对种群形成和适应的见解 |
Arciero, E. |
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N/A |
Himalayan whole-genome sequences provide insight into population formation and adaptation |
| 肝细胞癌阶段特异性转录组图谱：来自超级和差生存者的见解及预后特征鉴定 |
Xu, X. |
PDF |
N/A |
Stage-Specific Transcriptome Landscape of Hepatocellular Carcinoma: Insights from Super and Poor Survivors with Prognostic Signature Identification |
| 糖萼诱导的膜管形成 |
Xiao, K. |
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N/A |
Glycocalyx-induced formation of membrane tubes |
| 早期生活压力的性别二态结果背后的电路机制 |
Jiang, C. |
PDF |
N/A |
Circuit mechanisms underlying sexually dimorphic outcomes of early life stress |
| 基因组特征及多药耐药肺炎克雷伯菌株BCSIR-JUMIID的功能解析 |
Ahmed, M. F. |
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N/A |
Genomic characterization and functional insights of multidrug-resistant Klebsiella pneumoniae strain BCSIR-JUMIID |
| Cavin1结合纳米抗体揭示了N端卷曲螺旋域的结构灵活性及其受调控的相互作用 |
Gao, Y. |
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N/A |
Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain |
| 使用一种新方法ARGO（Analysis of Red Green Offset），在活体中可视化突触小泡蛋白Synaptogyrin/SNG-1的周转情况 |
Shiliaev, N. |
PDF |
N/A |
Visualizing turnover of synaptic vesicle protein Synaptogyrin/SNG-1 in vivo using a new method, ARGO (Analysis of Red Green Offset) |
| 由分布在膜表面的聚合酶驱动的肌动蛋白细丝组装 |
Mullins, D. |
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N/A |
Actin filament assembly driven by distributive polymerases clustered on membrane surfaces |
| 依那普利通过靶向抗氧化基因，经由磷酸化Smad1/5/9来缓解衰老。 |
Lyu, W. |
PDF |
N/A |
Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9 |
| 永生化的肠间质细胞——体外干细胞龛 |
Canella, M. |
PDF |
N/A |
Immortalized Intestinal Telocytes - A Stem Cell Niche In Vitro |
| Rho效应蛋白ARHGAP18通过YAP和Merlin协调Hippo通路的反馈回路，以调节细胞骨架和上皮细胞极性。 |
Murray, E. C. |
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N/A |
The Rho effector ARHGAP18 coordinates a Hippo pathway feedback loop through YAP and Merlin to regulate the cytoskeleton and epithelial cell polarity. |
| CRL4DCAF12对MCMBP的调控确保了DNA复制的最佳许可 |
Yadav, A. K. |
PDF |
N/A |
CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication |
| Notch信号通路在腺体干细胞/祖细胞中驱动促再生和迁移特性 |
Cinat, D. |
PDF |
N/A |
Notch Signaling Drives Pro-Regenerative and Migratory Traits in Glandular Stem/Progenitor Cells |
| 内质网-线粒体接触结构组成的灵活性 |
Covill-Cooke, C. |
PDF |
N/A |
Compositional Flexibility of the ER-Mitochondria Encounter Structure |
| 微管聚合和动力蛋白的抑制会损害与室管膜瘤相关的ZFTA-RELA融合蛋白的核定位及NF-κB的激活。 |
Ishii, M. |
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N/A |
Inhibition of microtubule polymerization and dynein impairs the nuclear localization of the ependymoma-associated ZFTA-RELA fusion protein and NF-κB activation |
| HelD是一种全球转录因子，能够增强快速生长的分枝杆菌中的基因表达。 |
Vankova, V. |
PDF |
N/A |
HelD is a Global Transcription Factor Enhancing Gene Expression in Rapidly Growing Mycobacteria |
| 通过邻近标记技术鉴定金黄色葡萄球菌与内皮细胞表面的相互作用组 |
Ruhling, M. |
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N/A |
Identification of the Staphylococcus aureus Endothelial Cell Surface Interactome by Proximity Labeling |
| 全球丰富滤食者对原绿球藻的捕食 |
Sweeney, C. |
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N/A |
Prochlorococcus predation by a globally abundant filter feeder |
| 细胞死亡效应下不可逆细胞分化的演变 |
Gao, Y. |
PDF |
N/A |
The evolution of irreversible cell differentiation under cell death effect |
| 泛素对SPRTN蛋白酶的变构激活维持了基因组的稳定性 |
Dürauer, S. |
PDF |
N/A |
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability |
| 古HLA-B*73:01等位基因的分子特征揭示了其独特的肽展示谱及与KIR2DL2的偏倚性结合 |
Ross, P. |
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N/A |
Molecular characterization of the archaic HLA-B*73:01 allele reveals presentation of a unique peptidome and skewed engagement by KIR2DL2 |
| 致癌性GNAQ/11诱导的IP3/钙信号通路重塑保护葡萄膜黑色素瘤免受钙驱动的细胞死亡 |
Garcia, C. |
PDF |
N/A |
Oncogenic GNAQ/11-induced remodeling of the IP3/Calcium signaling pathway protects Uveal Melanoma against Calcium-driven cell death |
| MASLD驱动的骨丢失的性二态性 |
Goldscheitter, G. M. |
PDF |
N/A |
Sexual dimorphism of MASLD-driven bone loss |
| 成年斯普拉格-道利大鼠中，中脑动脉反应性和血流动力学的性别差异与全身动脉硬度的变化无关 |
Yamaleyeva, L. |
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N/A |
Sex Differences in Middle Cerebral Artery Reactivity and Hemodynamics Independent from Changes in Systemic Arterial Stiffness in Adult Sprague-Dawley Rats |
| 玉米光合性状变异的定量遗传学 |
Ali, W. |
PDF |
N/A |
Quantitative genetics of photosynthetic trait variation in maize |
| 通过图像到图像的翻译实现无标签多重显微成像，克服像素级和图像级相似性之间的权衡 |
Morikura, T. |
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N/A |
Label-free multiplex microscopic imaging by image-to-image translation overcoming the trade-off between pixel- and image-level similarity |
| 隐蔽的肌肉活动揭示了动态的冻结状态，并为动物的行动做好了准备。 |
Hobbiss, A. F. |
PDF |
N/A |
Covert muscle activity reveals dynamic freezing states and prepares the animal for action |
| SMAC模拟物促使人类巨噬细胞吞噬活癌细胞 |
Liu, S. Y. |
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N/A |
SMAC mimetics induce human macrophages to phagocytose live cancer cells |
| 用于检测耐甲氧西林金黄色葡萄球菌光谱模式时间变化的非目标筛查方法及事后峰特征描述 |
Nichani, K. |
PDF |
N/A |
Non-targeted screening method for detecting temporal shifts in spectral patterns of Methicillin Resistance Staphylococcus aureus and post-hoc description of peak features |
| 景观中的农业实践对草原节肢动物有影响，此外还有当地条件和土地覆盖。 |
Brusse, T. |
PDF |
N/A |
Farming practices in the landscape have an impact on grassland arthropods, in addition to local conditions and land cover |
| 与流量相关的叶片和根系性状的协调影响森林群落构建 |
Ma, Z. |
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N/A |
Coordination of flux-related leaf and root traits impacts forest community assembly |
| 一种基于Omics的方法研究了拟南芥单个FERONIA和MARIS同源基因，证实了细胞壁完整性与脱落酸之间的联系。 |
Jobe, T. O. |
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N/A |
An Omics approach on Marchantia polymorpha single FERONIA and MARIS homologs confirms links between cell wall integrity and abscisic acid |
| 研究寄生植物中不同寄生水平下的长链非编码RNA |
Rodrigues, W. F. C. |
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N/A |
Investigating lncRNAs at different levels of parasitism in parasitic plants |
| 炎症小体传感器NLRP3与REV7相互作用，通过同源重组维持基因组完整性。 |
Burlet, D. |
PDF |
N/A |
The inflammasome sensor NLRP3 interacts with REV7 to maintain genome integrity through homologous recombination |
| Lamin B1依赖性调控人类有丝分裂分离酶 |
Picotto, J. |
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N/A |
Lamin B1-dependent regulation of human separase in mitosis |
| 利用电絮凝处理工艺对纺织印染废水进行处理和再加工 |
fatima, N. |
PDF |
N/A |
Treatment and reprocessing of textile dyeing wastewater by using the electrocoagulation treatment process |
| 环境DNA与社区科学：城市蜻蜓调查的优势与局限 |
Uche-Dike, R. |
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N/A |
Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys |
| 环境DNA与社区科学：城市蜻蜓调查的优势与局限 |
Uche-Dike, R. |
PDF |
N/A |
Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys |
| 早期生活环境温度对野生鸟类肠道微生物群的影响？一项实验方法 |
Ruuskanen, S. |
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N/A |
The effects of early-life ambient temperature on the gut microbiome of a wild bird? an experimental approach |
| pnetr：一个用于PnET系列森林生态系统模型的R包 |
Gao, X. |
PDF |
N/A |
pnetr: An R package for the PnET family of forest ecosystem models |
| 鼠李半乳糖醛酸聚糖-II二聚化缺陷损害了植物中生长与粘附维持之间的协调 |
Baba, A. I. |
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N/A |
Rhamnogalacturonan-II dimerization deficiency impairs the coordination between growth and adhesion maintenance in plants |
| 基于无人机的多光谱成像技术在洪涝耐受玉米品种识别中的应用：一个真实世界的案例研究 |
Mitchell, M. N. |
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N/A |
Drone-Based Identification of Flood-Tolerant Maize via Multispectral Imaging: A Real-World Case Study |
| BPMs通过促进Aux/IAA蛋白IAA10的非生长素依赖性降解来调控拟南芥幼苗的发育。 |
Ban, Z. |
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N/A |
BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 |
| 局部无序与工程光开关中增强的催化作用相关 |
McCormick, J. W. |
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N/A |
Local disorder is associated with enhanced catalysis in an engineered photoswitch |
| 背外侧前额叶皮层通过优化长期策略提取来驱动战略性放弃 |
Noel, J.-P. G. |
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N/A |
Dorsolateral prefrontal cortex drives strategic aborting by optimizing long-run policy extraction |
| 一种自动的、通用的错误信号在不同任务间共享，并预测不同感觉模态的置信度。 |
Davidson, M. J. |
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N/A |
An automatic domain-general error signal is shared across tasks and predicts confidence in different sensory modalities |
| 饥饿对雄性和雌性小鼠的趋避行为有不同的影响 |
Anversa, R. G. |
PDF |
N/A |
Hunger alters approach-avoidance behaviours differently in male and female mice |
| 评估利用磁共振成像（MRI）测量人脑中脑脊液（CSF）动力学全谱新方法的可行性：来自模拟研究的见解 |
van der Voort, E. |
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N/A |
Assessing the feasibility of a new approach to measure the full spectrum of CSF dynamics within the human brain using MRI: insights from a simulation study |
| 大黄蜂对氨基酸的味觉敏感性 |
Rossoni, S. |
PDF |
N/A |
Gustatory sensitivity to amino acids in bumblebees |
| 功能成熟与经验依赖性可塑性在成年新生嗅球多巴胺能神经元中 |
Tufo, C. |
PDF |
N/A |
Functional maturation and experience-dependent plasticity in adult-born olfactory bulb dopaminergic neurons |
| 赛洛西宾-NMDAR调节剂给药的协同行为与神经可塑性效应。 |
Ben Tal, T. |
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N/A |
Synergistic Behavioral and Neuroplastic Effects of Psilocybin-NMDAR Modulator Administration. |
| 胆碱能信号在多感官伽马刺激诱导的淀粉样蛋白周围血管清除中的作用 |
Lavoie, N. S. |
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N/A |
The role of cholinergic signaling in multi-sensory gamma stimulation induced perivascular clearance of amyloid |
| 通过综合应激反应感知胞外L-脯氨酸的可用性决定细胞竞争的结果。 |
Krishnan, S. |
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N/A |
Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition. |
| 草履虫的群集行为 |
Tabata, T. |
PDF |
N/A |
The swarming behaviors of Vorticella |
| 行动中规划：解决顺序实体任务中规划与行动的连续动态问题 |
Nuzzi, D. |
PDF |
N/A |
Planning-while-acting: addressing the continuous dynamics of planning and action in a sequential embodied task |
| 对未来的认知：海豚知道何时需要为未来记住某些事情。 |
Ortiz, S. T. |
PDF |
N/A |
Awareness of the future: Dolphins know when they need to remember for the future |
| 双向响应的温度感受器编码冷和暖 |
Bokiniec, P. |
PDF |
N/A |
Bidirectionally responsive thermoreceptors encode cool and warm |
| 正常衰老过程中脑血流量和葡萄糖代谢率在性别上的差异及其关联性。 |
Deery, H. |
PDF |
N/A |
Sex differences in the rates and association of cerebral blood flow and glucose metabolism in normative ageing. |
| GABA与谷氨酰胺-谷氨酸动态的解耦及其在触觉感知中的作用：一项fMRS研究 |
Pasanta, D. |
PDF |
N/A |
Decoupling of GABA and Glutamine-Glutamate Dynamics and their role in tactile perception: An fMRS Study |
| 高维数据空间中或多或少存在潜在变量？这正是问题的关键所在。 |
Vaccari, F. E. |
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N/A |
More or less latent variables in the high-dimensional data space? That is the question |
| 海马CA2神经元不成比例地表达AAV递送的遗传物质 |
Alexander, G. |
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N/A |
Hippocampal CA2 neurons disproportionately express AAV-delivered genetic cargo |
| 兴奋性和抑制性细胞的层依赖比率如何塑造平衡网络中的皮层编码 |
Alizadeh, A. |
PDF |
N/A |
How the layer-dependent ratio of excitatory to inhibitory cells shapes cortical coding in balanced networks |
| 癫痫持续时间中的周期及其在破伤风毒素大鼠模型中的潜在动态 |
Zarei Eskikand, P. |
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N/A |
Cycles in Seizure Duration and Their Underlying Dynamics in the Tetanus Toxin Rat Model |
| 异甘草素减轻了链脲佐菌素诱导的阿尔茨海默病小鼠模型中的认知障碍、脑内tau蛋白磷酸化及氧化应激。 |
Tang, Z. |
PDF |
N/A |
Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimers disease |
| st-DenseViT：一种用于动态脑网络密集预测的弱监督时空视觉Transformer |
Kazemivash, B. |
PDF |
N/A |
st-DenseViT: A Weakly Supervised Spatiotemporal Vision Transformer for Dense Prediction of Dynamic Brain Networks |
| 静息态功能连接和快速纺锤波的时间组织有助于健康老化中的情景记忆巩固 |
Hamel, A. |
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N/A |
Resting-state functional connectivity and fast spindle temporal organization contribute to episodic memory consolidation in healthy aging |
| 光遗传学操控细胞核背侧蛋白揭示了转录的时间需求及后果 |
Pimmett, V. L. |
PDF |
N/A |
Optogenetic manipulation of nuclear Dorsal reveals temporal requirements and consequences for transcription |
| P300/CBP催化的乙酰化通过激活DUX来保护次级合子基因组激活 |
Xiao, L. |
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N/A |
p300/CBP-catalyzed acetylation safeguards minor zygotic genome activation via activating DUX |
| 好斗的冲突会影响沙漠蚂蚁的归巢路径整合 |
Bollig, A. |
PDF |
N/A |
Aggressive conflict impacts path integration in homing desert ants |
| 一种用于生物分子凝聚物模拟的无序RNA粗粒度模型 |
Yasuda, I. |
PDF |
N/A |
A coarse-grained model of disordered RNA for simulations of biomolecular condensates |
| 通过多站点DMS探针在活细胞中同时映射RNA的二级、三级和四级结构 |
Saleem, I. |
PDF |
N/A |
Simultaneous mapping of RNA secondary, tertiary, and quaternary structure in living cells by multi-site DMS probing |
| IL-33/ST2信号轴在急性SARS-CoV-2感染中的发病机制中起驱动作用 |
Fleming, C. |
PDF |
N/A |
The IL-33/ST2 signaling axis drives pathogenesis in acute SARS-CoV-2 infection |
| 在合成人类肠道微生物群落中发现替代稳定状态 |
Garza, D. R. |
PDF |
N/A |
Discovery of alternative stable states in a synthetic human gut microbial community |
| 广泛保守的新型色素产生在枯草芽孢杆菌物种中的特征描述 |
Stannius, R. O. |
PDF |
N/A |
Characterization of widely conserved novel pigment production in Bacillus subtilis species |
| 真核生物核糖体中药物结合残基的自然变异 |
Chan, L. I. |
PDF |
N/A |
Natural variation of the drug-binding residues in eukaryotic ribosomes |
| 衣原体对兼性宿主多细胞性的适应 |
Helmlinger, L. |
PDF |
N/A |
The adaptation of chlamydiae to facultative host multicellularity |
| 揭示单一人皮肤部位共生棒状杆菌的多样性 |
Thomas, G. H. |
PDF |
N/A |
Revealing the diversity of commensal corynebacteria from a single human skin site |
| 折叠稀释和稀释液体积对细菌培养中菌落形成单位估计的影响 |
Jain, M. |
PDF |
N/A |
The impact of fold-dilution and diluent volume on the estimation of colony forming units in a bacterial culture |
| snRNA输出复合物协同组装的结构基础 |
Dubiez, E. |
PDF |
N/A |
Structural basis for the synergistic assembly of the snRNA export complex |
| 基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论的碱基对结合能计算 |
Deka, N. |
PDF |
N/A |
Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT |
| 用于下一代测序应用的果蝇总RNA中高效去除核糖体RNA |
Koppaka, O. |
PDF |
N/A |
EFFICIENT RIBOSOMAL RNA DEPLETION FROM DROSOPHILA TOTAL RNA FOR NEXT-GENERATION SEQUENCING APPLICATIONS |
| piRNA通路介导了Aedes蚊子体细胞和生殖细胞中LTR逆转录转座子的转录沉默。 |
Taskopru, E. |
PDF |
N/A |
The piRNA pathway mediates transcriptional silencing of LTR retrotransposons in the soma and germline of Aedes mosquitoes |
| 遗传性出血性毛细血管扩张症动静脉畸形中PIEZO1的过度表达 |
Park, H. |
PDF |
N/A |
PIEZO1 overexpression in hereditary hemorrhagic telangiectasia arteriovenous malformations |
| 系统探索NOD样受体中的域组合，揭示了Sordariales真菌中两种类型的NACHT域 |
bonometti, l. |
PDF |
N/A |
Systematic exploration of domain assortments in NOD-like receptors uncovers two types of NACHT domains in Sordariales fungi |
| 人类多能干细胞系中转录基因调控的全基因组单细胞CRISPRi图谱 |
Feng, C. |
PDF |
N/A |
A genome-scale single cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines |
| 通过CRISPR/Cas9和多个重组腺相关病毒（rAAV）高效创建和表征多千碱基敲入 |
Sentmanat, M. F. |
PDF |
N/A |
Efficient creation and characterization of multi-kilobase knockins by CRISPR/Cas9 and multiple rAAVs |
| 达卡市内河流微生物群落的时间和空间分布 |
ALOM, M. M. |
PDF |
N/A |
Temporal and spatial distribution of microbial community in urban river in Dhaka |
| 基因组组织与CUT&Tag（GO-CaT）技术识别了发育中人脑神经元中与核膜相关域的亚结构及其成熟过程 |
Zhang, C. |
PDF |
N/A |
Genome Organization with CUT and Tag (GO-CaT) identifies substructure and maturation of lamina-associated domains in neurons of the developing human brain |
| 从头非分隔化微生物用于纳米抗体的定向进化 |
Wu, D. |
PDF |
N/A |
De novo non-compartmentalized microorganism for directed evolution of nanobodies |
| 一类依赖结合蛋白的溶质转运蛋白，以百日咳博德特氏菌中的TAXI-GltS系统为例 |
Jaques, L. M. |
PDF |
N/A |
A new class of binding protein-dependent solute transporter exemplified by the TAXI-GltS system from Bordetella pertussis |
| 细菌磷脂酰胆碱N-甲基转移酶合成磷脂酰胆碱的结构基础 |
Watanabe, Y. |
PDF |
N/A |
Structural basis for phosphatidylcholine synthesis by bacterial phospholipid N-methyltransferases |
| 结合糖苷酶与纳米孔技术进行糖链测序 |
Gao, Z. |
PDF |
N/A |
Combining Glycosidases and Nanopore Technology for Glycan Sequencing |
| 对秀丽隐杆线虫中随年龄变化的胞外囊泡蛋白的元分析 |
Bhunia, P. K. |
PDF |
N/A |
A meta-analysis of age-dependent changes in extracellular vesicle proteins in C. elegans |
| 一种具有广泛底物谱的LarA消旋酶的催化及底物特异性的结构基础 |
Gatreddi, S. |
PDF |
N/A |
Structural Basis for Catalysis and Substrate Specificity of a LarA Racemase with a Broad Substrate Spectrum |
| 肠道微生物群衍生的GlcNAc-MurNAc是一种TLR4激动剂，能够保护宿主肠道。 |
Li, C. |
PDF |
N/A |
Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut |
| 使用CRISPR-Cas12a实现读出的抗逆转录病毒药物快速酶学检测 |
Singh, M. A. |
PDF |
N/A |
Rapid enzymatic assay for antiretroviral drug monitoring using CRISPR-Cas12a enabled readout |
| 建模和测量密码子使用如何调节细菌中蛋白质过表达过程中负担与产量之间的关系 |
Roots, C. T. |
PDF |
N/A |
Modeling and measuring how codon usage modulates the relationship between burden and yield during protein overexpression in bacteria |
| 重新利用的STAT3抑制剂乙胺嘧啶可控制分枝杆菌感染引起的血管通透性和分枝杆菌负荷 |
Han, D. J. |
PDF |
N/A |
The repurposed STAT3 inhibitor pyrimethamine controls mycobacterial infection-induced vascular permeability and mycobacterial burden |
| 合作簇结合调控了烟曲霉铁调节因子HapX在铁饥饿、充足和过量条件下的功能转换，以适应这些不同的铁环境。 |
Oberegger, S. |
PDF |
N/A |
Cooperative cluster-binding regulates the functional transitions of the Aspergillus fumigatus iron regulator HapX for adaptation to iron starvation, sufficiency and excess |
| 双向互动对双人踝关节和腕关节追踪的影响 |
Short, M. R. |
PDF |
N/A |
Effects of Uni- and Bidirectional Interaction During Dyadic Ankle and Wrist Tracking |
| NoButter：一个用于减少CosMx空间分子成像数据中转录本分散的R包 |
O'Hora, B. |
PDF |
N/A |
NoButter: An R package for reducing transcript dis-persion in CosMx Spatial Molecular Imaging Data |
| OmniSegger：一种用于细菌细胞延时图像分析的管道 |
Lo, T. W. |
PDF |
N/A |
OmniSegger: A time-lapse image analysis pipeline for bacterial cells |
| 协同多重相互作用介导伴侣蛋白HtrA1对α-突触核蛋白聚集的有效抑制 |
Chinchilla, P. |
PDF |
N/A |
Synergistic Multi-Pronged Interactions Mediate the Effective Inhibition of Alpha-Synuclein Aggregation by the Chaperone HtrA1 |
| 通过冷冻电子断层扫描技术揭示表皮生长因子受体在细胞外囊泡中的结构与组织 |
Gonzalez-Magaldi, M. |
PDF |
N/A |
Structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography |
| D-葡萄糖醛酸C5-差向异构酶通过结合EGFR抑制肾脏纤维化 |
Jing, X. |
PDF |
N/A |
D-glucuronyl C5-epimerase binds to EGFR to suppress kidney fibrosis |
| 设计针对肽-MHC-I复合物的高特异性结合剂 |
Liu, B. |
PDF |
N/A |
Design of high specificity binders for peptide-MHC-I complexes |
| 氮素富集改变了根瘤菌基因的选择 |
Hill, C. A. |
PDF |
N/A |
Nitrogen enrichment alters selection on rhizobial genes |
| 用于骨软骨界面再生工程的具有受控矿物梯度水凝胶的高级生物打印 |
Zhao, X. |
PDF |
N/A |
Advanced Bioprinting of Hydrogels with Controlled Mineral Gradients for Regenerative Engineering of the Osteochondral Interface |
| EasyPubPlot：一个用于快速组学数据探索和可视化的闪亮网络应用程序 |
Tien, N. T. N. |
PDF |
N/A |
EasyPubPlot: a shiny web application for rapid omics data exploration and visualization |
| Brisk：精确的资源高效型k-mer字典 |
Smith, C. |
PDF |
N/A |
Brisk: Exact resource-efficient dictionary for k-mers |
| 分子动力学语言模型 |
Murtada, M. H. |
PDF |
N/A |
Language Models for Molecular Dynamics |
| 加速全基因组比对在全基因组组装时代的重要性 |
Chandra, G. |
PDF |
N/A |
Accelerating whole-genome alignment in the age of complete genome assemblies |
| CASTER-DTA：用于预测药物-靶点亲和力的等变图神经网络 |
Kumar, R. |
PDF |
N/A |
CASTER-DTA: Equivariant Graph Neural Networks for Predicting Drug-Target Affinity |
| FIDDLE：一种从串联质谱预测化学公式的深度学习方法 |
Hong, Y. |
PDF |
N/A |
FIDDLE: a deep learning method for chemical formulas prediction from tandem mass spectra |
| G蛋白抑制剂YM-254890是一种别构粘合剂。 |
Trent, T. |
PDF |
N/A |
The G protein inhibitor YM-254890 is an allosteric glue |
| 一个注释详尽的三阴性乳腺癌患者来源异种移植瘤生物库，包含未经治疗的初始样本以及在新辅助化疗全程中的纵向样本。 |
Rinkenbaugh, A. L. |
PDF |
N/A |
An annotated biobank of triple negative breast cancer patient-derived xenografts featuring treatment-naive and longitudinal samples throughout neoadjuvant chemotherapy |
| 粘附-悬浮塑性促进循环肿瘤细胞的传播和定植 |
Huh, H. D. |
PDF |
N/A |
Adherent-suspension plasticity promotes the dissemination and colonization of circulating tumor cells |
| 含爱泼斯坦-巴尔病毒产物的外泌体促进鼻咽癌中与白血病抑制因子相关的巨噬细胞免疫抑制极化 |
Liu, T.-T. |
PDF |
N/A |
Epstein-Barr viral product-containing exosome facilitates LIF-associated immunosuppressive polarization of macrophage in nasopharyngeal carcinoma |