| 靶向噬菌体T4纳米颗粒逆转CD4+人类T细胞中的HIV-1潜伏期 |
Batra, H. |
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N/A |
Targeted Bacteriophage T4 Nanoparticles Reverse HIV-1 Latency in CD4+ Human T Cells |
| 内体趋化因子受体信号复合体调控细胞迁移的中心机制 |
Hahn, H. |
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N/A |
Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration |
| 撤回：类风湿性关节炎合并尿路感染患者中奇异变形杆菌分离株的免疫学参数 |
Abdul, F. R. |
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N/A |
WITHDRAWN: Immunological parameters of Proteus mirabilis isolates in Rheumatoid Arthritis patients with urinary tract infections |
| 整合代谢规模和共存理论 |
Saavedra, S. |
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N/A |
Integrating metabolic scaling and coexistence theories |
| 在人类癌细胞中，输入蛋白α在微核中积累，并与基因组不稳定性相关联。 |
Miyamoto, Y. |
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N/A |
Importin α accumulates in micronuclei and associates with genomic instability in human cancer cells |
| 揭示早期人类B细胞淋巴发生调控机制及其在B细胞急性淋巴母细胞白血病发病机制中的意义 |
Planell, N. |
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N/A |
Uncovering the regulatory landscape of early human B-cell lymphopoiesis and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia |
| TEMPTED：纵向微生物组研究的时间感知降维方法 |
Shi, P. |
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N/A |
TEMPTED: Time-Informed Dimensionality Reduction for Longitudinal Microbiome Studies |
| 后顶叶内侧皮层中的中尺度功能架构 |
Hira, R. |
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N/A |
Mesoscale functional architecture in medial posterior parietal cortex |
| 通过内侧视前区异质神经元集群对女性性欲的射精后抑制 |
Ishii, K. K. |
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N/A |
Post-ejaculatory Inhibition of Female Sexual Drive via Heterogeneous Neuronal Ensembles in the Medial Preoptic Area |
| 宽过渡态系综作为酶催化关键组分 |
Jara, G. E. |
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N/A |
Wide Transition-State Ensemble as Key Component for Enzyme Catalysis |
| 通过三维几何形态测量法分析泰坦龙类（恐龙，蜥脚类）后肢形态的演化，揭示了宽步态姿势作为巨型化的适应性特征。 |
Paramo Blazquez, A. |
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N/A |
Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D Geometric Morphometrics reveals wide-gauge posture as an exaptation for gigantism |
| Vangl-Celsr极性复合物在胞内囊泡运输中的紊乱是导致气管-食管形态发生先天性异常的潜在原因。 |
Edwards, N. A. |
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N/A |
Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis |
| 斑马鱼中的折叠与融合神经形成过程需要Vangl2蛋白的参与。 |
MacGowan, J. |
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N/A |
Fold-and-fuse neurulation in zebrafish requires Vangl2 |
| USP7抑制促进老年骨质疏松小鼠早期骨整合 |
Zhou, F. |
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N/A |
USP7 Inhibition Promotes Early Osseointegration in Senile Osteoporotic Mice |
| 在缺乏P物质和CGRPα信号的小鼠中，疼痛持续存在。 |
MacDonald, D. I. |
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N/A |
Pain persists in mice lacking both Substance P and CGRPα signaling |
| 海马体中空间支架的情节记忆和联想记忆 |
Chandra, S. |
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N/A |
Episodic and associative memory from spatial scaffolds in the hippocampus |
| 神经信号反卷积分析的可解释深度学习 |
Tolooshams, B. |
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N/A |
Interpretable deep learning for deconvolutional analysis of neural signals |
| 选择性上皮表达KRASG12D突变在Oncopigs中驱动胰腺导管性肿瘤 |
Jara, C. P. |
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Selective epithelial expression of KRASG12D mutation drives ductal pancreatic neoplasia in Oncopigs |
| 扣带皮层塑造了出生后早期社会发声的发展 |
Nagarajan, G. |
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N/A |
Cingulate cortex shapes early postnatal development of social vocalizations |
| 三重态态布居对GFP型荧光及光漂白的影响 |
Byrdin, M. |
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N/A |
Impact of Triplet State Population on GFP-type Fluorescence and Photobleaching |
| 支配肝脏的迷走神经感觉神经元在喂食高脂饮食的小鼠中，对于脂肪肝和焦虑样行为的发展起着不可或缺的作用。 |
Hwang, J. |
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N/A |
Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis and anxiety-like behavior in mice fed a high-fat diet. |
| 两个对抗性的基因调控网络在低温下驱动拟南芥根毛生长 |
Urzua, T. |
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N/A |
Two antagonistic gene regulatory networks drive Arabidopsis root hair growth at low temperature |
| 一个包含超过34,000种脊椎动物的物种形成速率、不确定性以及存在-缺失矩阵的数据集 |
Vasquez-Restrepo, J. D. |
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N/A |
A dataset containing speciation rates, uncertainty, and presence-absence matrices for more than 34,000 vertebrate species |
| 反馈在视觉工作记忆和长期记忆期间，均能调节皮层反应的空间调谐性。 |
Woodry, R. |
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N/A |
Feedback scales the spatial tuning of cortical responses during both visual working memory and long-term memory |
| 在抗病毒反应中，Fish CDK2招募Dtx4通过泛素化降解TBK1 |
Lu, L.-F. |
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Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response |
| 腹侧苍白球的GABA能神经元在雄性大鼠中驱动摄食行为，但在雌性大鼠中则不然。 |
Scott, A. |
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N/A |
Ventral pallidal GABAergic neurons drive consumption in male, but not female rats |
| 家犬驯化过程中的基因型和表型结果 |
Sweetalana, |
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N/A |
Genotypic and phenotypic consequences of domestication in dogs |
| 有限的证据表明，概率性提示对光栅诱发的事件相关电位和方向解码性能有影响。 |
den Ouden, C. |
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N/A |
Limited evidence for probabilistic cueing effects on grating-evoked event-related potentials and orientation decoding performance |
| 贝叶斯奥卡姆剃刀优化复杂系统模型的方法 |
Wang, C. |
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N/A |
Bayesian Occam's Razor to Optimize Models for Complex Systems |
| 氘代谢成像表型通过葡萄糖转化动力学揭示小鼠胶质母细胞瘤的异质性 |
Simoes, R. V. |
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N/A |
Deuterium Metabolic Imaging Phenotypes Mouse Glioblastoma Heterogeneity Through Glucose Turnover Kinetics |
| 新生儿血液中自闭症谱系障碍的性别特异性DNA甲基化特征 |
Mouat, J. S. |
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Sex-specific DNA methylation signatures of autism spectrum disorder in newborn blood |
| 坏死导致PolgD257A突变小鼠对结核分枝杆菌的易感性增加 |
Mabry, C. J. |
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N/A |
Necrosis drives susceptibility to Mycobacterium tuberculosis in PolgD257A mutator mice |
| 实验诱导的疼痛和感觉异常对无疼痛年轻个体中袖带加压参数变化的响应不同 |
Skalski, J. |
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Experimentally induced pain and paresthesia respond differently to parameter changes of cuff-based compression in pain-free young individuals |
| 角质形成细胞向皮肤鳞状细胞癌的遗传进化 |
Tandukar, B. |
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N/A |
Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma |
| 在早期儿童时期，皮层区域的一个子集表现出类似于成人的功能网络模式。 |
Tu, J. C. |
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A Subset of Cortical Areas Exhibit Adult-like Functional Network Patterns in Early Childhood |
| 微塑料作为抗菌素耐药性的新型促进剂：浓度、组成和尺寸对大肠杆菌多重耐药性的影响 |
Gross, N. |
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N/A |
Microplastics as a novel facilitator for antimicrobial resistance: Effects of concentration, composition, and size on Escherichia coli multidrug resistance |
| 空间转录组分析揭示HDAC抑制通过调节小胶质细胞动态在小鼠中保护免受缺血性中风 |
Jayaraj, K. |
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N/A |
Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice |
| 调节相互抑制的机制控制UNC-13的功能切换 |
Liu, H. |
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N/A |
Mechanism that regulates the mutual inhibition controls functional switch of UNC-13 |
| 青春期对促肾上腺皮质激素释放因子受体1的拮抗作用会导致行为可塑性和杏仁核转录组特征的持续性、性别特异性变化。 |
Martz, J. |
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Peripubertal antagonism of corticotropin-releasing factor receptor 1 results in sustained, sex-specific changes in behavioral plasticity and the transcriptomic profile of the amygdala |
| 揭示具有微生物组相互作用特性的马铃薯品种，以实现可持续农业生产 |
Zhao, T. |
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N/A |
Unveiling the potato cultivars with microbiome interactive traits for sustainable agricultural production |
| wtf杀手减数分裂驱动因子的功能性限制 |
Srinivasa, A. N. |
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N/A |
Functional constraints of wtf killer meiotic drivers |
| 缺铁会导致大豆根部转录发生变化，进而破坏其耐旱性。 |
Hasan, M. R. |
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N/A |
Fe deficiency causes transcriptional shift in roots leading to disruption of drought tolerance in soybean |
| 个人空间与群体灾难中的集体行为 |
Lugo, I. |
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N/A |
The personal space and the collective behavior of crowd disasters |
| 味蕾中的死亡：死亡的味觉受体细胞被胶质样I型细胞吞噬 |
Wilson, C. E. |
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N/A |
Death in the taste bud: engulfment of dying taste receptor cells by glial-like Type I cells |
| 社会结构对和尚鹦鹉发声灵活性的影响 |
Smeele, S. Q. |
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N/A |
The effect of social structure on vocal flexibility in monk parakeets |
| 在高壁面剪切应力条件下，几种PfEBA和PfRH配体对恶性疟原虫疟疾血期生长至关重要。 |
Kals, E. |
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N/A |
Under conditions of high wall shear stress, several PfEBA and PfRH ligands are important for Plasmodium falciparum malaria blood-stage growth |
| 催产素受体调控草原田鼠的滥交行为及发育 |
Sharma, R. |
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N/A |
Oxytocin receptor controls promiscuity and development in prairie voles |
| 通过味觉受体检测细菌可启动细胞免疫反应 |
Mazariegos, A. N. |
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N/A |
Detection of bacteria through taste receptors primes the cellular immune response |
| 果蝇在特征贫乏环境中的空间学习 |
Chen, Y. |
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N/A |
Spatial learning in feature-impoverished environments in Drosophila |
| Lgl在有丝分裂退出时重置Par复合物膜加载，以实现不对称神经干细胞分裂 |
LaFoya, B. |
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N/A |
Lgl resets Par complex membrane loading at mitotic exit to enable asymmetric neural stem cell division |
| 等压标记在MaxQuant中的更新 |
Ferretti, D. |
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N/A |
Isobaric labeling update in MaxQuant |
| 照亮根土力学 |
Le Houx, J. |
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N/A |
Illuminating root-soil mechanics |
| 顶枕叶伽马经颅交流电刺激对视觉空间注意任务中行为表现和神经活动的影响 |
Zheng, T. |
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N/A |
After-effects of Parieto-occipital Gamma Transcranial Alternating Current Stimulation on Behavioral Performance and Neural Activity in Visuo-spatial Attention Task |
| 模拟欧洲范围内人类蜱传脑炎（TBE）发生概率的时空年度变化 |
Dagostin, F. |
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N/A |
Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe |
| 通过激光诱导的Soret效应实现亚稳态相分离液滴生成及长时间DNA富集 |
Kobayashi, M. |
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N/A |
Metastable phase-separated droplet generation and long-time DNA enrichment by laser-induced Soret effect |
| 通过多模态方法分析亚麻荠和高粱对环境胁迫的响应特性 |
Seitz, K. A. |
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N/A |
Characterizing the Responses of Camelina and Sorghum to Environmental Stress through a Multi-Modal Approach |
| 对多样性杂交小鼠研究中寿命的分析确定了多个与长寿相关的基因座 |
Mullis, M. N. |
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N/A |
Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci |
| 委内瑞拉Llanos地区三种空中捕食蝙蝠的饮食与食性生态位划分 |
Azofeifa Romero, Y. |
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N/A |
Diet and trophic niche partitioning of three aerial hawking bat species in the Venezuelan Llanos |
| 海拔和海洋屏障塑造了新西兰卡波卡波瓦伊（Uropetala）蜻蜓的分布、扩散和多样性 |
Tolman, E. R. |
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N/A |
Elevational and Oceanic Barriers Shape the Distribution, Dispersal and Diversity of Aotearoa's Kapokapowai (Uropetala) Dragonflies |
| 基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论的碱基对结合能计算 |
Deka, N. |
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N/A |
Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT |
| 通过自然转化在人类肠道微生物组中测量微生物群落范围内的抗生素抗性传播 |
Chowdhury, N. N. |
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N/A |
Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome |
| 对Lasius蚁属的基因组数据进行去污染处理，以实现准确的物种划分和杂交检测 |
Jecha, K. |
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N/A |
Decontaminating genomic data for accurate species delineation and hybrid detection in the Lasius ant genus |
| 体内网络活动的调节驱动了轴突起始段处轴-轴突突触的纳米尺度重构 |
Compans, B. |
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N/A |
In vivo modulation of network activity drives the nanoscale reorganisation of axo-axonic synapses at the axon initial segment |
| 青春期和成年期怀孕期间的压力会影响下丘脑中的组蛋白乙酰化调节因子。 |
Luther, L. A. |
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N/A |
Stress during puberty and adulthood pregnancy impact histone acetylation regulators in the hypothalamus |
| Lats1/2对于发育中的血管重塑和适应剪切应力的生物力学适应至关重要。 |
Cowdin, M. A. |
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N/A |
Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress |
| 古老社会染色体上超基因的重复进化 |
Lajmi, A. |
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N/A |
Repeated evolution of supergenes on an ancient social chromosome |
| 森林不仅仅是树木：单倍型与推断的溯祖图 |
Fritze, H. |
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N/A |
A forest is more than its trees: haplotypes and inferred ARGs |
| GluA1的细胞质尾部调控细胞内AMPA受体的运输以及对齿状回GABA能中间神经元的突触传递，调节对新奇刺激的反应 |
Leana-Sandoval, G. |
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N/A |
The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty |
| 背外侧前额叶皮层细胞类型特异性增强子。 |
He, J. |
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N/A |
Cell Type Specific Enhancers for Dorsolateral Prefrontal Cortex. |
| 转录调控元件的方向性 |
Chen, Y. |
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N/A |
Directionality of Transcriptional Regulatory Elements |
| 电生理图作为一种功能性读数，用于评估果蝇黑腹果蝇神经退行性变模型中的神经元完整性。 |
Manuel, N. |
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N/A |
Electroretinograms as a functional readout of neuronal integrity in neurodegeneration models of Drosophila melanogaster |
| 嘌呤能受体P2Y13调控室管膜下区成年神经干细胞的激活与分裂模式 |
Paniagua-Herranz, L. |
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N/A |
Purinergic Receptor P2Y13 Controls Activation and Mode of Division in Subependymal Adult Neural Stem Cells |
| H5N1适应牛细胞的多基因决定因素 |
Turnbull, M. L. |
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N/A |
POLYGENIC DETERMINANTS OF H5N1 ADAPTATION TO BOVINE CELLS |
| 分枝杆菌核小体相关蛋白NapM表现出应激诱导的隔膜定位，并调节细胞膜基因表达 |
Milcarz, K. |
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N/A |
The mycobacterial nucleoid-associated protein NapM exhibits stress-induced septal localization and modulates cell envelope gene expression |
| 对涡虫再生特异性的比较分析揭示了轴向cWnt信号梯度对组织极性的贡献。 |
Cleland, J. P. |
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N/A |
A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient. |
| 出生体重差异、基因表达与DNA甲基化：双胞胎表观遗传学研究的综述 |
Wadji, D. L. |
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N/A |
Birth weight discordance, gene expression, and DNA methylation: A review of epigenetic twin studies |
| 相对于群体成员的空间位置会影响狐獴（Suricata suricatta）的体重增加 |
Mosia, R. |
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N/A |
Spatial position relative to group members affects weight gain in meerkats (Suricata suricatta) |
| 光学层析成像技术在旋转驱动下重建多散射样品的3D运动和结构 |
Moser, S. |
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N/A |
Optical tomography reconstructing 3D motion and structure of multiple-scattering samples under rotational actuation |
| 耶氏解脂耶氏酵母中基因编码报告基因的总体评价 |
Zhang, H. |
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N/A |
General assessment of genetically-encoded reporters in Yarrowia lipolytica |
| Alevin-fry-atac 利用虚拟颜色实现单细胞ATAC-seq数据的快速且低内存消耗的基因组伪比对，从而进行准确的数据映射。 |
Singh, N. P. |
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N/A |
Alevin-fry-atac enables rapid and memory frugal mapping of single-cell ATAC-seq data using virtual colors for accurate genomic pseudoalignment |
| extgfa：一种低内存的基因组图谱磁盘表示方法 |
Dabbaghie, F. |
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N/A |
extgfa: a low-memory on-disk representation of genome graphs |
| 斜面显微镜中的主动远程聚焦稳定 |
Nguyen, D. T. |
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N/A |
Active Remote Focus Stabilization in Oblique Plane Microscopy |
| Cetuximab-IRDye800偶联物在EGFR过表达肿瘤中的荧光和光声信号的时间动力学 |
Saad, M. A. |
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N/A |
Temporal dynamics of fluorescence and photoacoustic signals of a Cetuximab-IRDye800 conjugate in EGFR-overexpressing tumors |
| 重新评估爱泼斯坦-巴尔病毒（EBV）与美国乳腺癌之间的关联 |
Hu, C. C. |
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N/A |
Reevaluating the Association Between Epstein-Barr Virus (EBV) and Breast Cancer in the United States |
| 通过sEV液体活检揭示miR-451a和miR-142-3p作为非小细胞肺癌的预后标志物 |
Burdiel Herencia, M. |
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N/A |
Unveiling miR-451a and miR-142-3p as Prognostic Markers in NSCLC via sEV Liquid Biopsy |
| 正电子发射断层扫描（PET）示踪剂能够成像高CD73表达的癌症。 |
Dobelmann, C. |
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N/A |
Positron emission tomography (PET) tracer enables imaging of high CD73 expression in cancer |
| 细胞自主性游离脂肪酸受体4-ChemR23信号级联保护心肌细胞免受缺血损伤 |
Puccini, S. |
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N/A |
A Cell Autonomous Free fatty acid receptor 4 - ChemR23 Signaling Cascade Protects Cardiac Myocytes from Ischemic Injury |
| 在Physcomitrella光生物反应器中生产蜘蛛丝蛋白的重组生产 |
Ramezaniaghdam, M. |
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N/A |
Recombinant production of spider silk protein in Physcomitrella photobioreactors |
| 产后第一年内存在亲子关系障碍的母亲的情绪处理：一项改编的fMRI情绪GoNoGo任务的结果 |
Eckstein, M. |
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N/A |
Emotion processing in mothers with bonding disorder during the first year postpartum: Results of an adapted fMRI emotional GoNoGo Task |
| 短暂的新生儿视觉剥夺对人类腹侧枕颞皮层发育的影响 |
Mattioni, S. |
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N/A |
Impact of a transient neonatal visual deprivation on the development of the ventral occipito-temporal cortex in humans |
| LRRK2 G2019S突变在感染性结肠炎模型中激发了细胞内在的中性粒细胞效应功能增强和肠道炎症 |
Pei, J. |
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N/A |
LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis |
| 红李（Leea rubra Blume）抗氧化、抗糖尿病和抗菌活性的体外研究 |
Mai, H. V. |
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N/A |
In Vitro Studies of Antioxidant, Antidiabetic, and Antibacterial Activities of Leea rubra Blume |
| 在小鼠和人类中移植后高度功能性效应CD8+ T细胞程序的鉴定 |
Cohen, G. S. |
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N/A |
Identification of a Highly Functional Effector CD8+ T Cell Program After Transplantation in Mice and Humans |
| 欧洲亚型蜱传脑炎病毒在韩国的兴起（2005-2014年）可能与人类活动有关 |
Kovalev, S. Y. |
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N/A |
European Subtype Tick-Borne Encephalitis Virus Emergence In South Korea (2005 - 2014) Can Be Associated With Human Activity |
| TTF2通过将TRAIP泛素连接酶与Pol epsilon耦合，驱动有丝分裂复制体的解体和MiDAS。 |
FUJISAWA, R. |
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N/A |
TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Pol epsilon |
| 细胞类型特异性体内蛋白质组与多拷贝突变型甲硫氨酰tRNA合成酶小鼠品系 |
Schuman, E. M. |
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N/A |
Cell type-Specific In Vivo Proteomes with a Multi-copy Mutant Methionyl t-RNA Synthetase Mouse Line |
| 利用原子力显微镜绘制海鞘胚胎在卵裂阶段的单细胞流变学图谱 |
Kotani, T. |
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N/A |
Mapping single-cell rheology of ascidian embryos in the cleavage stages using AFM |
| 皮质微管作为模板，组织了胞吐作用的纳米级图案化。 |
Lindeboom, J. |
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N/A |
Cortical microtubules act as a template to organize nano-scale patterning of exocytosis |
| 两种新型红色FRET ERK生物传感器，波长范围为670-720纳米。 |
DeCuzzi, N. L. |
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N/A |
Two Novel Red-FRET ERK Biosensors in the 670-720nm Range. |
| 双皮质素结构域蛋白ZYG-8对微管的硬化作用有助于在秀丽隐杆线虫合子分裂过程中纺锤体的定向 |
Cueff, L. |
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N/A |
Microtubule stiffening by doublecortin-domain protein ZYG-8 contributes to spindle orientation during C. elegans zygote division |
| Rbfox1和mir-33调控JAK/STAT信号在果蝇成体肌生成中的多效性作用 |
Mukherjee, A. |
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N/A |
Rbfox1 and mir-33 regulate pleiotropic roles of JAK/STAT signalling during adult myogenesis in Drosophila melanogaster |
| 不同的细胞和分子机制导致几丁质沉积，这有助于D. melanogaster中两种几丁质合成酶的特异性。 |
Bertran-Mas, J. |
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N/A |
Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster. |
| 饮食中的余甘子（印度醋栗，Amla）可提高果蝇模型中早期营养不良的生育力和抗氧化应激能力。 |
Padmaraj, P. |
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N/A |
Dietary Phyllanthus emblica L. (Indian gooseberry, Amla) improves fecundity and resistance to oxidative stress in a Drosophila melanogaster model of early-life malnutrition. |
| 海洋硅藻热耐受性的演变：热胁迫下的代谢策略。 |
Aranguren-Gassis, M. |
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N/A |
Evolution of thermal tolerance in marine diatoms: Metabolic strategies under heat stress. |
| 细胞对冷冻-解冻应激产生类似静止状态的趋同适应 |
Tvishamayi, C. |
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N/A |
Convergent cellular adaptation to a quiescence-like state in response to freeze-thaw stress |
| 近似贝叶斯计算支持了人类囊胚阶段胚胎中染色体嵌合现象的高发生率。 |
Yang, Q. |
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N/A |
Approximate Bayesian computation supports a high incidence of chromosomal mosaicism in blastocyst-stage human embryos |
| 鉴定并分析扁虫Hofstenia miamia中的微小RNA的发育特征 |
Duan, Y. |
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N/A |
Identification and developmental profiling of microRNAs in the acoel worm Hofstenia miamia |
| Indel驱动的刀豆氨酸tRNA编辑去乙酰酶CtdA的进化 |
Mayans, O. |
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N/A |
Indel-driven evolution of the canavanine tRNA-editing deacetylase enzyme CtdA |
| 无标记下使用全息断层显微镜和U-Net对内皮细胞线粒体进行可视化与分割 |
Michael, R. |
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N/A |
Label-Free Visualization and Segmentation of Endothelial Cell Mitochondria Using Holotomographic Microscopy and U-Net |
| 在人类肾脏中整合空间多重蛋白质成像和转录组学，追踪近端小管再生潜力的时间线 |
Asghari, M. |
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N/A |
Integration of spatial multiplexed protein imaging and transcriptomics in the human kidney tracks the regenerative potential timeline of proximal tubules |
| 多特征AI集成与投票系统在MAPKAPK2抑制剂发现中的优化 |
Chen, H. |
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N/A |
Optimization of a Multi-Feature AI Ensemble and Voting System for MAPKAPK2 Inhibitor Discovery |
| 使用反事实的定量归因 |
Adjavon, D.-Y. |
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N/A |
Quantitative Attributions with Counterfactuals |
| 涂层刷的电荷分布驱动染色体间的吸引力 |
Sorichetti, V. |
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N/A |
Charge distribution of coating brush drives inter-chromosome attraction |
| 使用冷冻电子断层扫描技术对染色质生物分子凝聚物进行定量空间分析 |
Zhou, H. |
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N/A |
Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography |
| 黏附-悬浮转变促进黑色素瘤的转移扩散 |
Lee, D. K. |
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N/A |
Adherent-to-suspension transition promotes melanoma metastatic dissemination |
| 林奇综合征相关尿路上皮癌中受限的超突变及TERT启动子突变的缺失 |
Nikkola, J. |
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N/A |
Constrained hypermutation and absence of TERT promoter mutations in Lynch syndrome-associated urothelial cancer |
| 一种新型RyR2选择性稳定剂可预防和改善应激诱导的室性心动过速中的严重心律失常 |
Kurebayashi, N. |
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N/A |
A novel RyR2-selective stabilizer prevents and ameliorates severe arrhythmias in stress-induced ventricular tachycardia |
| 大肠杆菌应激反应调节子中的动态异质性介导基因激活和抗菌肽耐受性 |
Blassick, C. M. |
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N/A |
Dynamic heterogeneity in an E. coli stress response regulon mediates gene activation and antimicrobial peptide tolerance |
| 一种多层次形式体系，用于捕捉上皮-间质可塑性中混合表型的特征 |
Hari, K. |
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N/A |
A multi-level formalism to capture the characteristics of hybrid phenotypes in Epithelial-Mesenchymal Plasticity |
| fluxTrAM：将基于示踪剂的代谢组学数据整合到原子分辨率的基因组规模代谢网络中，用于代谢通量分析 |
Huang, L. |
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N/A |
fluxTrAM: Integration of tracer-based metabolomics data into atomically resolved genome-scale metabolic networks for metabolic flux analysis |
| 非甾体抗炎药物的代谢组学反应 |
Ghosh, S. |
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N/A |
Metabolomic Response to Non-Steroidal Anti-Inflammatory Drugs |
| 规范模型揭示了青春期前儿童在精神病理学维度上存在不同的皮层异常 |
Deng, Q. |
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N/A |
Normative models reveal distinct cortical abnormalities to dimensions of psychopathologies in preadolescents |
| 干扰素-γ通过IRF1对炎症NF-κB靶基因的表观遗传调控 |
Mishra, B. |
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Epigenetic Regulation of Inflammatory NF-κB Target Genes by IFN-γ via IRF1 |
| Zfh1与Nau之间的相互作用通过一个由mir-9a介导的负反馈回路，在果蝇（Drosophila melanogaster）中调控Rbfox1及其靶标Stat92E的肌源性阶段依赖性表达。 |
Mukherjee, A. |
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N/A |
The interplay between Zfh1 and Nau orchestrates the myogenic stage-dependent expression of Rbfox1 and its target Stat92E via a mir-9a-mediated negative feedback loop in Drosophila melanogaster |
| 从讣告中识别家庭结构并将其与电子健康记录中的患者进行匹配。 |
Mayer, J. G. |
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N/A |
Identifying Family Structures from Obituaries and Matching them to Patients in an Electronic Heath Record. |
| 深度学习与浅层混合纳米孔-Illumina测序用于经济实惠且准确的检测种系变异。 |
Gambardella, G. |
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N/A |
Deep-leaning and shallow hybrid Nanopore-Illumina sequencing for affordable and accurate detection of germline variants. |
| CEACAM1通过脂噬依赖的铁死亡介导心房颤动，靶向ABCA1 |
Hu, W.-w. |
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CEACAM1 Targets ABCA1 to Mediate Atrial Fibrillation via Lipophagy-Dependent Ferroptosis |
| 独特的最小临床截短突变对BRCA1相互作用组的不同重塑 |
Chen, J. |
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N/A |
Differential Remodeling of the BRCA1 Interactome by a Unique Minimal Clinical Truncation Mutation |
| 从质谱指纹图谱进行基因本体的大规模预测揭示了新的代谢基因功能 |
Vavricka, C. |
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N/A |
Genome-scale prediction of gene ontology from mass fingerprints reveals new metabolic gene functions |
| Cycledesigner 利用 RFdiffusion 和 HighFold 设计针对特定目标的环肽结合剂 |
Zhang, C. |
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N/A |
Cycledesigner Leveraging RFdiffusion and HighFold to Design Cyclic Peptide Binders for Specific Targets |
| 古基因组学支持东地中海和西地中海印欧语言之间存在深远分化。 |
Yediay, F. E. |
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N/A |
Ancient genomics support deep divergence between Eastern and Western Mediterranean Indo-European languages |
| 烟草烟雾改变了肺腺癌中突变、选择和上位性的格局 |
Dasari, K. |
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N/A |
Tobacco smoke alters the landscape of mutation, selection, and epistasis in lung adenocarcinoma |
| NEFFy：一种用于计算有效序列数量的多功能工具 |
Haghani, M. |
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N/A |
NEFFy: A Versatile Tool for Computing the Number of Effective Sequences |
| 在非小细胞肺癌中，细胞间的融合在药物选择下赋予了适应性优势 |
Shultes, P. V. |
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N/A |
Cell-Cell Fusion in NSCLC Confers a Fitness Benefit Under Drug Selection |
| 长期高温影响甘蓝型油菜种子的成熟度和种皮完整性 |
Prabhullachandran, U. |
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N/A |
Long-term high temperatures affect seed maturation and seed coat integrity in Brassica napus |
| 单细胞海洋捕食者的全球种群结构 |
Latorre, F. |
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N/A |
Global population structure of a unicellular marine predator |
| 网络结构和适应性觅食对物种丰富的植物-传粉者群落传粉服务的影响 |
Valdovinos, F. S. |
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N/A |
Effect of network structure and adaptive foraging on pollination services of species-rich plant-pollinator communities |
| 研究设计和在生物银行规模数据集中对有害罕见变异的采样 |
Steiner, M. C. |
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N/A |
Study design and the sampling of deleterious rare variants in biobank-scale datasets |
| 拟谷盗近缘物种基因组中卫星DNA的动态演化 |
Veseljak, D. |
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N/A |
Dynamic evolution of satellite DNAs drastically differentiates the genomes of Tribolium sibling species |
| 从长读取重叠区域估计基因组大小 |
Hall, M. B. |
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N/A |
Genome size estimation from long read overlaps |
| 人脑和猴脑中的连接性：探讨穹窿在轻度认知障碍和阿尔茨海默病中的因果作用 |
Pelekanos, V. |
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N/A |
Connectivity in the human and the monkey brain probes causal involvement of the fornix in Mild Cognitive Impairment and Alzheimer's Disease |
| 在小鼠阿尔茨海默病、动脉粥样硬化及阿尔茨海默病合并动脉粥样硬化模型中表征血管功能 |
Eyre, B. |
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N/A |
Characterizing vascular function in mouse models of Alzheimer's disease, atherosclerosis, and mixed Alzheimer's and atherosclerosis |
| 周围炎症刺激导致小胶质细胞吞噬谷氨酸能输入，并降低伏隔核D1中型多棘神经元的兴奋性。 |
Nakajima, S. |
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N/A |
Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult |
| 突触乙酰胆碱通过烟碱受体在基底外侧杏仁核中诱导出尖波涟漪。 |
Bratsch-Prince, J. X. |
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N/A |
Synaptic acetylcholine induces sharp wave ripples in the basolateral amygdala through nicotinic receptors |
| 异步亚基转换先于乙酰胆碱受体激活 |
Thompson, M. J. |
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N/A |
Asynchronous subunit transitions precede acetylcholine receptor activation |
| MEG信号揭示了顶叶前额叶皮层中手臂姿势编码和内在运动计划的存在。 |
Blohm, G. |
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N/A |
MEG signals reveal arm posture coding and intrinsic movement plans in parietofrontal cortex |
| 用于连续测量亚100纳摩尔尼古丁的荧光蛋白生物传感器的水凝胶封装 |
Nichols, A. L. |
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N/A |
Hydrogel encapsulation of a designed fluorescent protein biosensor for continuous measurements of sub-100 nanomolar nicotine |
| 综合现象学和脑连接性研究表明，在高级冥想（如禅那）中，非线性处理发生了变化。 |
Potash, R. M. |
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N/A |
Integrated phenomenology and brain connectivity demonstrate changes in nonlinear processing in jhana advanced meditation |
| 过度活跃的神经网络促进阿尔茨海默病小鼠模型中的tau蛋白扩散 |
Barbour, A. J. |
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N/A |
Hyperactive neuronal networks facilitate tau spread in an Alzheimer's disease mouse model |
| ASH1L通过动态调节染色质环境调控人类神经元结构与功能 |
Jhanji, M. |
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N/A |
Dynamic Regulation Of The Chromatin Environment By ASH1L Modulates Human Neuronal Structure And Function |
| 对埃及伊蚊基因表达的分析表明，蚊子发育早期阶段的遗传调控发生了变化。 |
dos Santos, R. C. |
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N/A |
Analysis of gene expression in Aedes aegyptisuggests changes in early genetic control of mosquito development |
| 双语接触与性别塑造婴儿对语音特征大脑反应的发展轨迹 |
Puertollano, M. |
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N/A |
Bilingual Exposure and Sex Shape Developmental Trajectories of Brain Responses to Speech-Sound Features in Infants |
| PDGFRα+间充质基质细胞在前列腺发育过程中促进上皮谱系的形成 |
Maiti, D. |
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N/A |
PDGFRα+ Mesenchymal Stromal Cells Contribute to Epithelial Lineages during Prostate Development |
| 通过dPGC1控制线粒体动力学限制了Yorkie诱导的果蝇致癌性生长 |
Sew, W. Q. G. |
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N/A |
Control of mitochondrial dynamics by dPGC1 limits Yorkie-induced oncogenic growth in Drosophila |
| 果蝇对细菌肽聚糖的感知反应整合了正负信号 |
Montanari, M. |
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N/A |
Drosophila's sensory responses to bacterial peptidoglycan integrates positive and negative signals |
| 海洋蠕虫Capitella teleta对神经化学操纵非常敏感，这一发现是通过一种新型的高通量行为工具揭示的。 |
Hendershot, M. |
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N/A |
The marine worm Capitella teleta is sensitive to neurochemical manipulation, as revealed via a novel high-throughput behavioural tool |
| 雌性虎皮鹦鹉更倾向于选择与自己觅食技能不同的雄性。 |
Zou, Y. |
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N/A |
Female budgerigars prefer males with foraging skills that differ from their own |
| 前额叶星形胶质细胞的过度激活通过中枢犬尿氨酸的代谢途径损害认知 |
Beilmann, V. |
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N/A |
Overactivation of prefrontal astrocytes impairs cognition through the metabolic pathway of central kynurenines |
| 静息态fMRI去噪流程在运动校正和行为预测中的有效性。 |
Pavlovich, K. |
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N/A |
The efficacy of resting-state fMRI denoising pipelines for motion correction and behavioural prediction. |
| 解码支持层次任务泛化的任务表示 |
Lee, W. |
PDF |
N/A |
Decoding task representations that support generalization in hierarchical task |
| 不同强度单侧手握疲劳对双侧运动的影响 |
Knorz, A. L. |
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N/A |
The effects of varying intensities of unilateral handgrip fatigue on bilateral movement |
| 早期生活压力暴露的相似性与成年早期神经表征的相似性相关 |
Ilomäki, M. |
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N/A |
Similarity in Early Life Stress Exposure is Associated with Similarity in Neural Representations in Early Adulthood |
| 自主运动在大脑大静脉中引起早期且远端的血流动力学下降 |
Eyre, B. |
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N/A |
Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins |
| ARBEL：一种基于光学的图像分析机器学习工具，用于三维疼痛行为的自动分类 |
Barkai, O. |
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N/A |
ARBEL: A Machine Learning Tool with Light-Based Image Analysis for Automatic Classification of 3D Pain Behaviors |
| VGCC辅助亚基α2δ1是一种与细胞外GluA1相互作用的蛋白质，并调节长时程增强（LTP）、空间记忆和癫痫易感性。 |
Leana-Sandoval, G. |
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N/A |
The VGCC auxiliary subunit α2δ1 is an extracellular GluA1 interactor and regulates LTP, spatial memory, and seizure susceptibility |
| 重复性脑熵（BEN）在沉思期间的改变 |
Lu, J. |
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N/A |
Reproducible Brain Entropy (BEN) Alterations During Rumination |
| 纹状体星形胶质细胞影响多巴胺动态和行为状态转换 |
Lazaridis, I. |
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N/A |
Striatal Astrocytes Influence Dopamine Dynamics and Behavioral State Transitions |
| 人类在感知推断中使用了对听觉空间和时间不确定性的过度自信估计。 |
Hong, F. |
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N/A |
Humans use overconfident estimates of auditory spatial and temporal uncertainty for perceptual inference |
| “多少才算足够？”——儿童自然fMRI功能连接可靠性的考量 |
Rai, S. S. |
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N/A |
How much is 'enough'? Considerations for functional connectivity reliability in pediatric naturalistic fMRI |
| 早期生活逆境改变成年期腹侧被盖区神经元：对压力增加和强迫行为易感性的神经机制的启示 |
Gugula, A. |
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N/A |
Early-life adversity alters adult nucleus incertus neurons: implications for neuronal mechanisms of increased stress and compulsive behavior vulnerability |
| RIG-I介导的神经元特异性I型干扰素信号在FUS-ALS中诱导神经退行性变，并为（FUS-）ALS提供了新的生物标志物驱动的个性化治疗选择。 |
Naumann, M. |
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N/A |
RIG-I mediated neuron-specific IFN type 1 signaling in FUS-ALS induces neurodegeneration and offers new biomarker-driven individualized treatment options for (FUS-)ALS |
| KIF3C在调控小脑发育过程中Bergmann胶质细胞密度和模式形成中发挥作用 |
Waas, B. |
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N/A |
KIF3C Regulates Bergmann Glia Density and Patterning during Cerebellar Development |
| 由于产前大麻二酚暴露导致的焦虑发展轨迹的性别特异性破坏 |
Iezzi, D. |
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N/A |
Sex-specific disruptions in the developmental trajectory of anxiety due to prenatal cannabidiol exposure |
| 人类听觉大脑中时间整合的信号：心理洞察、脑电图证据及临床应用 |
Xu, H. |
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N/A |
A signal of temporal integration in the human auditory brain: psychological insights, EEG evidence, and clinical application |
| 人类听觉大脑中的时间整合信号：心理学洞察、脑电图证据及临床应用 |
Xu, H. |
PDF |
N/A |
A signal of temporal integration in the human auditory brain: psychological insights, EEG evidence, and clinical application |
| KlebPhaCol：一个由社区驱动的克雷伯氏菌研究资源发现了一种与人类肠道相关的新型肠道噬菌体目。 |
Rothschild-Rodriguez, D. |
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N/A |
KlebPhaCol: A community-driven resource for Klebsiella research identified a novel gut phage order associated with the human gut |
| 利用孕早期阴道微生物群早期预测子痫前期 |
Kindschuh, W. F. |
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N/A |
Early prediction of preeclampsia using the first trimester vaginal microbiome |
| 在丝状蓝藻中，氰外排酶B对于运动性、生物膜形成和藻青素生产是必不可少的。 |
Parrett, G. |
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N/A |
Cyanoexosortase B is essential for motility, biofilm formation and scytonemin production in a filamentous cyanobacterium |
| 绘制犬类微生物组图谱：来自狗衰老项目的见解 |
Bamberger, T. |
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N/A |
Mapping the canine microbiome: Insights from the Dog Aging Project |
| 小鼠长期肠道衣原体定植期间肠道屏障破坏的洞察：单细胞转录组学方法 |
Tian, Q. |
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N/A |
Insights into Intestinal Barrier Disruption During Long-Term Gut Chlamydia Colonization in Mice: A Single-Cell Transcriptomic Approach |
| 研究辣椒素在通过细胞外囊泡促进柯萨奇病毒B3传播中的潜在作用 |
Chatterjee, S. |
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N/A |
Investigating the potential role of capsaicin in facilitating the spread of coxsackievirus B3 via extracellular vesicles |
| 沿海植物的根系有助于稳定海洋藻类固定的碳。 |
Hellige, I. |
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N/A |
Roots of coastal plants stabilize carbon fixed by marine algae |
| 识别基孔肯雅病毒nsP2 ATPase的抑制剂 |
Navarro, H. |
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Identification of Inhibitors of Chikungunya virus nsP2 ATPase |
| 整合应激反应沉默的分子基础 |
Yang, Z. |
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N/A |
The molecular basis of integrated stress response silencing |
| 人类线粒体RNA聚合酶结构揭示转录起始位点和滑移机制 |
Shen, J. |
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Human mitochondrial RNA polymerase structures reveal transcription start-site and slippage mechanism |
| 转录因子GATA1识别RNA的独特机制 |
Ugay, D. A. |
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A distinct mechanism of RNA recognition by the transcription factor GATA1 |
| 先进的肽纳米颗粒能够实现对多种细胞类型进行强大且高效的基因编辑器递送。 |
Gustafsson, O. |
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N/A |
Advanced Peptide Nanoparticles Enable Robust and Efficient delivery of gene editors across cell types |
| SARS-CoV-2 N蛋白的动态集合揭示了头对头卷曲螺旋驱动的寡聚化和相分离现象 |
Hernandez, G. G. |
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N/A |
Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation |
| 靶向内质网应激和亚硝基氧化还原失衡在神经内分泌前列腺癌中的治疗作用：一氧化氮的作用 |
FIRDAUS, F. |
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N/A |
Targeting Endoplasmic Reticulum Stress and Nitroso-Redox Imbalance in Neuroendocrine Prostate Cancer: The Therapeutic Role of Nitric Oxide |
| 发散思维和创造性人格对多米尼加大学科学产出和创新质量的影响 |
Montano Medina, G. A. |
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N/A |
The Influence of Divergent Thinking and Creative Personality on the Quality of Scientific Production and Innovation in a Dominican University |
| 通过纳米孔测序和引导学习实现非天然碱基的直接高通量解卷积 |
Perez, M. |
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N/A |
Direct high-throughput deconvolution of unnatural bases via nanopore sequencing and bootstrapped learning |
| 使用Orbitrap Ascend Tribrid质谱仪对亲和纯化蛋白复合物进行FAIMS分析 |
Goswami, P. |
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Analysis of FAIMS for the Study of Affinity-Purified Protein Complexes Using the Orbitrap Ascend Tribrid Mass Spectrometer |
| 环境暴露和家族背景会改变SARS-CoV-2感染后神经病理学和炎症的诱发。 |
Chatterjee, D. |
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Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection. |
| L-天冬酰胺酶治疗在T细胞依赖的B细胞激活模型中，对非恶性B细胞产生可逆的免疫调节和免疫抑制效应。 |
Hadzic, A. |
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L-Asparaginase treatment induces reversible immunoregulatory and immunosuppressive effects in non-malignant B cells in a model of T-cell dependent B cell activation |
| 根据临床表型分层的系统性硬化症患者循环浆细胞样树突状细胞的独特代谢特征 |
Ferreira, B. H. |
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Distinct metabolic profiles of circulating plasmacytoid dendritic cells in systemic sclerosis patients stratified by clinical phenotypes |
| 土壤细菌中性脂质脂肪酸：碳储存还是腐殖质标记？ |
Gorka, S. |
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Soil bacterial neutral lipid fatty acids: Markers for carbon storage or necromass? |
| 扩展CarD相互作用网络：CrsL是耻垢分枝杆菌中的一种新型转录因子 |
Shoman, M. |
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Expanding the CarD interaction network: CrsL is a novel transcription factor in Mycobacterium smegmatis |
| 全基因组测序揭示Enterobacter hormaechei为尼日利亚西南部六家三级护理医院的关键血流病原体。 |
Oni, F. I. |
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Whole genome Sequencing Reveals Enterobacter hormaechei as a key Bloodstream Pathogen in six tertiary care hospitals in southwestern Nigeria. |
| 利用两种和三种物种的FliC嵌合体拯救细菌运动性 |
Scadden, J. |
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Rescue of bacterial motility using two and three-species FliC chimeras |
| 利用两种和三种物种的FliC嵌合体拯救细菌运动性 |
Scadden, J. |
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N/A |
Rescue of bacterial motility using two and three-species FliC chimeras |
| 小龙虾病原菌Candidatus Paracoxiella cheracis n.g. n.sp.的完整基因组序列为我们深入了解其致病机制及Coxiellaceae科的系统发育关系提供了重要线索。 |
Ingle, D. J. |
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The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family |
| 小龙虾病原菌Candidatus Paracoxiella cheracis n.g. n.sp.的完整基因组序列揭示了其致病机制及Coxiellaceae科的系统发育关系。 |
Ingle, D. J. |
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The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family |
| 在铀污染的含水层中，微生物群落的多样性适度下降，组成变化显著 |
Fan, Y. |
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Modest functional diversity decline and pronounced composition shifts of microbial communities in a uranium-contaminated aquifer |
| 金黄色葡萄球菌POT转运蛋白DtpT在人巨噬细胞内二/三肽摄取和谷胱甘肽利用中的独特作用 |
Khan, I. |
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Distinct roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages |
| 针对TREM2-TYROBP跨膜结合的药物筛选 |
Cobas-Carreno, M. |
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Drug screening targeting TREM2-TYROBP transmembrane binding |
| 更大的宿主影响和杂交性：入侵海藻宿主如何优于同时存在的本地物种 |
Ghotbi, M. |
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Greater host influence and promiscuity: How an invasive seaweed host has advantages over co-occurring natives |
| 土地覆盖和气候变化对印度鸟类栖息地的影响 |
Diengdoh, V. L. |
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N/A |
Impact of land cover and climate change on habitat of Indian birds |
| 在波动环境中可塑性和性状置换的演变 |
Chevin, L.-M. |
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Evolution of plasticity and character displacement in a fluctuating environment |
| 四倍体黑莓刺的遗传控制 |
Johns, C. A. |
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Genetic Control of Prickles in Tetraploid Blackberry |
| GAGER：基因调控网络辅助基因表达恢复 |
Chowdhury, M. Z. U. S. |
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GAGER: gene regulatory network assisted gene expression restoration |
| 人β细胞中甘氨酸受体活性的分子相关性 |
Gomes, A. S. |
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Molecular Correlates of Glycine Receptor Activity in Human β Cells |
| 人类诱导多能干细胞（iPSCs）中染色体12三体性激增的起源 |
Narozna, M. |
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Origin of Chromosome 12 Trisomy Surge in Human Induced Pluripotent Stem Cells (iPSCs) |
| 热诱导的磷脂酰丝氨酸变化驱动HSPA1A在质膜的定位 |
Low, J. |
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Heat-Induced Phosphatidylserine Changes Drive HSPA1A's Plasma Membrane Localization |
| 葡萄糖-6-磷酸酶对于果蝇精子的能量代谢、运动能力及生育力是必需的。 |
Hedjazi, S. |
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Glucose-6-phosphatase is required for sperm energy metabolism, motility and fertility in Drosophila |
| 三维hiPSC-心脏微组织工业化用于高通量心脏安全性和药物发现筛选 |
de Korte, T. |
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Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening |
| 成人口腔的免疫调节结构 |
Fernandes Matuck, B. |
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N/A |
The Immunoregulatory Architecture of the Adult Oral Cavity |
| Retromer对抗阿片类药物引起的μ阿片受体下调 |
Dagunts, A. |
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Retromer Opposes Opioid-Induced Downregulation of the Mu Opioid Receptor |
| 多梳抑制复合物2促进动脉粥样硬化斑块的脆弱性 |
Joshi, D. |
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Polycomb Repressive Complex 2 promotes atherosclerotic plaque vulnerability |
| 沿着和逆着受限的粘附梯度进行单细胞迁移 |
Fortunato, I. C. |
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N/A |
Single cell migration along and against confined haptotactic gradients |
| 光遗传学诱导的微管乙酰化揭示了定向细胞迁移中肌动蛋白-微管交叉对话的分子动力学 |
Deb Roy, A. |
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Optogenetically Induced Microtubule Acetylation Unveils the Molecular Dynamics of Actin-Microtubule Crosstalk in Directed Cell Migration |
| 通过mRNA定位控制上皮组织结构 |
Mason, D. E. |
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N/A |
Control of Epithelial Tissue Organization by mRNA Localization |
| BECLIN-1 通过调节内吞运输、F-肌动蛋白组织和溶酶体功能，对维持胃肠道上皮完整性至关重要。 |
Juliani, J. |
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BECLIN-1 is Essential for the Maintenance of Gastrointestinal Epithelial Integrity by Regulating Endocytic Trafficking, F-actin Organization and Lysosomal Function |
| Erk1/2对Pak1的磷酸化作用于细胞迁移需要Arl4D作为支架蛋白的参与。 |
Chang, T.-W. |
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The phosphorylation of Pak1 by Erk1/2 for cell migration requires Arl4D acting as a scaffolding protein |
| MAGI2的调控及其在足细胞病变诊断中的应用 |
Siegerist, F. |
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N/A |
The Regulation of MAGI2 and its Diagnostic Application in Podocytopathies |
| 秀丽隐杆线虫的huntingtin蛋白，即htt-1，在应激条件下能够促进强效的自噬诱导和生存。 |
Chung, C. H. |
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C. elegans huntingtin, htt-1, promotes robust autophagy induction and survival under stress conditions |