| 利用深度领域自适应匹配从体内尖峰序列中重建电路连接性 |
Sheng, K. |
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N/A |
Reconstructing Circuit Connectivity from in vivo Spike Trains Using Deep Domain-Adaptive Matching |
| 典型想象者和无想象症者中的视觉心理意象：一项毫米级7-T fMRI研究 |
Liu, J. |
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N/A |
Visual mental imagery in typical imagers and in aphantasia: A millimeter-scale 7-T fMRI study |
| 音高并非螺旋：探究音乐音高在不同任务和经验中的结构 |
Marjieh, R. |
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N/A |
Pitch is Not a Helix: Probing the Structure of Musical Pitch Across Tasks and Experience |
| 用于研究果蝇联想学习的驱动线 |
Shuai, Y. |
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N/A |
Driver lines for studying associative learning in Drosophila |
| BRAF抑制剂二聚体选择性和结合协同作用的机制 |
Clayton, J. |
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N/A |
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors |
| 通过个性化碱基编辑在iPSC衍生的神经元中建模和校正蛋白质构象疾病 |
Konishi, C. T. |
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N/A |
Modeling and Correction of Protein Conformational Disease in iPSC-derived Neurons through Personalized Base Editing |
| 通过共表达AsCas12a超变体、T7 RNA聚合酶和胞嘧啶碱基编辑器，改进了利什曼原虫的基础编辑和功能筛选。 |
May, N. H. |
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N/A |
Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA Polymerase, and a cytosine base editor |
| 一个反馈驱动的脑类器官平台能够实现自动维护和高分辨率神经活动监测。 |
Voitiuk, K. |
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N/A |
A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring |
| 细胞内口袋构象通过μ阿片受体决定信号传导 |
Cooper, D. A. |
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N/A |
Intracellular pocket conformations determine signaling through the μ opioid receptor |
| 果蝇腿部本体感受和外感受神经回路的差异 |
Lee, S.-Y. J. |
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N/A |
Divergent neural circuits for proprioceptive and exteroceptive sensing of the Drosophila leg |
| 细菌双链DNA病毒基因组图谱的探索揭示了在广泛镶嵌性中存在ANI差距 |
Ndovie, W. |
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N/A |
Exploration of the genetic landscape of bacterial dsDNA viruses reveals an ANI gap amidst extensive mosaicism |
| SAUSI：一种用于测量社交回避与动机的综合测验 |
Grammer, J. |
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N/A |
SAUSI: an integrative assay for measuring social aversion and motivation |
| 降低腹内侧下丘脑（VMH）中神经元一氧化氮合酶（nNOS）的表达会增加雌性小鼠的体重和血糖水平，同时减少其体力活动。 |
Hirschberg, P. R. |
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N/A |
Reducing neuronal nitric oxide synthase (nNOS) expression in the ventromedial hypothalamus (VMH) increases body weight and blood glucose levels while decreasing physical activity in female mice. |
| 可解释的蛋白质-DNA相互作用通过结构-序列优化捕捉 |
Zhang, Y. |
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N/A |
Interpretable Protein-DNA Interactions Captured by Structure-Sequence Optimization |
| 竞争效应调节微小RNA池的组成 |
Raak, S. B. |
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N/A |
Competition effects regulating the composition of the microRNA pool |
| 解读情绪状态下内侧前额叶皮层下行通路中的隐藏变异性 |
Lai, C.-H. |
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N/A |
Decoding the hidden variabilities in mPFC descending pathways across emotional states |
| 海南岛非结核分枝杆菌的分布、流行及耐药性 |
Xu, X. |
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N/A |
Distribution, Prevalence, and Antibiotic Resistance of Non-Tuberculous Mycobacteria on Hainan Island |
| 支原体滑动运动的F1样ATP酶的二聚体组装 |
Toyonaga, T. |
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N/A |
Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma |
| 消费者体型和栖息地偏好对资源分布的空间指纹 |
Little, C. J. |
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N/A |
Spatial fingerprint of consumer body size and habitat preference on resource distribution |
| 朝着昆虫相机陷阱图像的边缘处理方向发展 |
Bjerge, K. |
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N/A |
Towards edge processing of images from insect camera traps |
| 平行HIV-1适应性景观塑造了人类和猕猴中病毒动力学，这些宿主能够产生广谱中和抗体。 |
Shimagaki, K. S. |
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N/A |
Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies. |
| 躯体感觉知觉的兴奋性调节并不依赖于前馈神经元群体的放电。 |
Stephani, T. |
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N/A |
Excitability modulations of somatosensory perception do not depend on feedforward neuronal population spikes |
| 条件序列-结构整合：一种用于精准抗体工程和亲和力优化的创新方法 |
Jamialahmadi, B. |
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N/A |
Conditional Sequence-Structure Integration: A Novel Approach for Precision Antibody Engineering and Affinity Optimization |
| 非周期性和振荡系统构成了人类领域一般认知的基础 |
Lu, R. |
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N/A |
Aperiodic and oscillatory systems underpinning human domain-general cognition |
| PeakClimber：一种用于使用指数高斯函数精确量化复杂多分析物HPLC色谱图的软件工具 |
Derrick, J. |
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N/A |
PeakClimber: A software tool for the accurate quantification of complex multianalyte HPLC chromatograms using the exponential Gaussian function |
| SOI：利用直系同源指数进行同线性基因组的鲁棒鉴定及其在进化基因组学中的广泛应用 |
Zhang, R.-G. |
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N/A |
SOI: Robust identification of orthologous synteny with the Orthology Index and broad applications in evolutionary genomics |
| 双光子NAD(P)H-FLIM显示，与宿主巨噬细胞在接触青蒿素衍生物后不同，猪蛔虫幼虫的能量代谢未受影响。 |
Musimbi, Z. D. |
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N/A |
Two-Photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure |
| 具身视角：角回和楔前叶在自然事件记忆中解码自我身份 |
Iriye, H. |
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N/A |
An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events |
| 血清素类迷幻药DOI会损害听觉皮层的异常检测能力 |
Horrocks, M. |
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N/A |
The serotonergic psychedelic DOI impairs deviance detection in the auditory cortex |
| BindCraft：功能性蛋白质结合剂的一步设计 |
Pacesa, M. |
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N/A |
BindCraft: one-shot design of functional protein binders |
| 中性粒细胞表现出不同的迁移表型，这些表型受跨内皮迁移的调控。 |
Schwartz, A. B. |
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N/A |
Neutrophils exhibit distinct migration phenotypes that are regulated by transendothelial migration |
| 伏隔核D2表达神经元：通过节律性光遗传刺激平衡奖励与舔舐中断 |
Requejo-Mendoza, N. |
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N/A |
Nucleus accumbens D2-expressing neurons: Balancing reward and licking disruption through rhythmic optogenetic stimulation |
| 高吞吐量蛋白质组学和磷酸蛋白质组学分析的福尔马林固定石蜡包埋组织 |
Haines, M. |
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N/A |
High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissue |
| 寄生虫、宿主、猎物和环境之间的LINE-RTE逆转录转座子的水平转移。 |
Brann, T. |
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N/A |
Horizontal transfer of a LINE-RTE retrotransposon among parasite, host, prey and environment. |
| 编程群体组成和多细胞形态的合成比例计算 |
An, B. |
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N/A |
Synthetic ratio computation for programming population composition and multicellular morphology |
| 转录因子GATA1识别RNA的独特机制 |
Ugay, D. A. |
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N/A |
A distinct mechanism of RNA recognition by the transcription factor GATA1 |
| 大豆（Glycine max. (L.) Merrill）品系表型形态特征及遗传多样性评估，以促进育种进展 |
Saha, M. |
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N/A |
Pheno-Morphological Characterization and Genetic Diversity Assessment of Grain and Vegetable Soybean (Glycine max. (L.) Merrill) Lines for Breeding Advancements |
| 单倍二倍体加速了昆虫线粒体基因组的进化 |
Pakrashi, A. |
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N/A |
HAPLODIPLOIDY ACCELERATES MITOGENOME EVOLUTION IN INSECTS |
| RpiBeh：一种多用途的开源解决方案，用于实时追踪和基于行为驱动的啮齿动物神经行为学闭环干预 |
Sun, Y. |
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N/A |
RpiBeh: a multi-purpose open-source solution for real-time tracking and behavior-driven closed-loop interventions in rodent neuroethology |
| 冷冻电镜显示，源自心脏IGLV6的AL纤维可以具有多态性。 |
Bassett, P. T. |
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N/A |
Cryo-EM reveals that cardiac IGLV6-derived AL fibrils can be polymorphic |
| 科学出版物中定量聚合酶链反应（qPCR）方法的报告质量 |
Drude, N. I. |
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N/A |
Reporting quality of quantitative polymerase chain reaction (qPCR) methods in scientific publications |
| 你可以做到！利用已发表的关于水螅口部张开的本科生研究来训练本科生 |
Hackler, S. |
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N/A |
You can do it! Using published undergraduate research on Hydra mouth opening to train undergraduates |
| Ozboneviz：澳大利亚在FAIR 3D影像和扩展生物多样性收藏方面的先例 |
Weisbecker, V. |
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N/A |
Ozboneviz: An Australian Precedent in FAIR 3D Imagery and Extended Biodiversity Collections |
| 符号和非符号数字在数字线二等分任务中对中心识别的影响不同 |
Porru, A. |
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N/A |
Symbolic and Non-Symbolic numbers differently affect centre identification in a number-line bisection task |
| 发作间期抑制性网络的崩溃允许癫痫发作扩散 |
Makhoul, G. S. P. |
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N/A |
Collapse of Interictal Suppressive Networks Permits Seizure Spread |
| 控制感能缓解压力 |
Fielder, J. C. |
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N/A |
Sense of control buffers against stress |
| 执行功能与更新预测表征之间的相互作用 |
Pedraza, F. |
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N/A |
The interplay between executive functions and updating predictive representations |
| 前扣带皮层损伤会破坏人类处理奖励的电生理特征 |
Oerlemans, J. |
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N/A |
Lesions of anterior cingulate cortex disrupt an electrophysiological signature of reward processing in humans |
| 外周免疫细胞对刺激的反应将帕金森病从前驱期到临床期的进展进行了分层 |
Mark, J. R. |
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N/A |
Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages |
| 模拟驾驶环境中器乐对双任务干扰的影响 |
Khadiv, E. |
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N/A |
The Impact of Instrumental Music on Dual-task Interference in a Simulated Driving Environment |
| ForestForward：可视化和访问过去五十年综合世界森林数据 |
Tejada-Gutierrez, E. L. |
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N/A |
ForestForward: visualizing and accessing integrated world forest data from the last fifty years |
| 接受个体化新抗原导向疫苗治疗的转移性癌症患者全面纵向ctDNA监测 |
Schenk, D. |
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N/A |
Comprehensive Longitudinal ctDNA Monitoring in Metastatic Cancer Patients Treated with an Individualized Neoantigen-directed Vaccine |
| PISA：多功能3D单分子光片显微镜 |
Taniguchi, Y. |
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N/A |
PISA: versatile microscope for 3D single molecule light sheet imaging |
| 积雪草组织培养衍生的胞外囊泡：多角度应用于护肤领域 |
Chang, T.-M. |
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N/A |
Centella asiatica Tissue Culture-Derived Extracellular Vesicles: A Multifaceted Approach to Skincare Applications |
| 比较功能性和结构性神经影像数据中的个体内部和个体间相关脑连接性 |
Di, X. |
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N/A |
Comparing Intra- and Inter-individual Correlational Brain Connectivity from Functional and Structural Neuroimaging Data |
| 周围传入纤维对脊髓感觉输入的调节。寻找中继站 |
Slawinska, U. |
PDF |
N/A |
Modulation of sensory input to the spinal cord by peripheral afferent fibres. Searching for relays |
| 通过台式质谱仪进行多模态脂质-蛋白质-组织学成像，探索阿尔茨海默病小鼠中的Aβ斑块微环境 |
Mueller, E. |
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N/A |
Exploring the Abeta Plaque Microenvironment in Alzheimer's Disease Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer |
| 评估空间化声学场景中变化检测的行为和神经相关性 |
Poole, K. C. |
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N/A |
Assessing Behavioral and Neural Correlates of Change Detection in Spatialized Acoustic Scenes |
| 在果蝇翅膀上皮发育过程中，Frizzled1和Frizzled2在低Wingless水平下的竞争性生存中并非冗余。 |
Hingole, S. |
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N/A |
Frizzled1 and Frizzled2 are not redundant for competitive survival under low-Wingless levels in the developing Drosophila wing epithelium |
| 重新审视生物医学研究中的胚胎鸡模型：一个科学案例 |
McGrew, M. J. |
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N/A |
A scientific case for revisiting the embryonic chicken model in biomedical research |
| ANKRD5：轴丝的一个关键组成部分，对精子运动和男性生育能力至关重要 |
Yu, S. |
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N/A |
ANKRD5: a key component of the axoneme required for spermmotility and male fertility |
| 通过血淋巴和环境DNA调查，在普吉特海湾的软壳蛤（Mya arenaria）中识别出双壳类可传播性肿瘤的暴发 |
Weinandt, S. A. |
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N/A |
Identification of an Outbreak of Bivalve Transmissible Neoplasia in Soft-Shell Clams (Mya arenaria) in the Puget Sound Using Hemolymph and eDNA Surveys |
| 圈养繁殖野兔的饮食干预未能使肠道微生物群富集具有野生功能的微生物 |
Aizpurua, O. |
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N/A |
Dietary intervention in captive-bred hares fails to enrich gut microbiomes with wild-like functions |
| 在非洲发现已驯化“迷幻蘑菇”Psilocybe cubensis 最亲近的野生近亲 |
Bradshaw, A. J. |
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N/A |
Discovery of the closest free-living relative of the domesticated "magic mushroom" Psilocybe cubensis in Africa |
| 基于TurboID的邻近标记技术鉴定出维持秀丽隐杆线虫E颗粒完整性和小RNA稳态的新型生殖系蛋白 |
Li, K. |
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N/A |
TurboID-based proximity labeling identifies novel germline proteins that maintain E granule integrity and small RNA homeostasis in C. elegans |
| 一种与腺苷淀粉样纤维形成相关的先天性代谢错误模型可减少TDP-43在酵母中的聚集和毒性 |
Park, S. |
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N/A |
A model of inborn metabolism errors associated with adenine amyloid-like fiber formation reduces TDP-43 aggregation and toxicity in yeast |
| 条纹田鼠（Apodemus agrarius）的ERGA-BGE参考基因组，该物种在欧洲中部和东部广泛分布且数量众多。 |
Janzekovic, F. |
PDF |
N/A |
ERGA-BGE Reference Genome of the Striped Field Mouse (Apodemus agrarius), a Widespread and Abundant Species in Central and Eastern Europe |
| 两种涉及EDN3的结构变异导致鸡的色素沉着过度 |
Ma, C. |
PDF |
N/A |
Two distinct structural variants involving EDN3 cause hyperpigmentation in chicken |
| 人类基因组在核DNA和无细胞DNA中的覆盖情况 |
Luo, J. |
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N/A |
Coverage landscape of the human genome in nucleus DNA and cell-free DNA |
| 乌干达和博茨瓦纳感染艾滋病毒的儿童中存在高KIR多样性 |
John, M. |
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N/A |
High KIR diversity in Uganda and Botswana children living with HIV |
| 通过超滤纯化环状RNA |
Cuevas, K. d. J. G. |
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N/A |
Purifying circular RNA by ultrafiltration |
| 工程化人体淋巴结基质模型用于研究间质液流和T细胞外排 |
Hammel, J. H. |
PDF |
N/A |
Engineered human lymph node stroma model for examining interstitial fluid flow and T cell egress |
| 将无催化活性的RusA与FokI核酸酶融合，并结合PNA，可实现可编程的位点特异性双链DNA断裂 |
Mahfouz, M. |
PDF |
N/A |
Fusions of catalytically inactive RusA to FokI nuclease coupled with PNA enable programable site-specific double-stranded DNA breaks |
| 调整组织模板及其细胞居民的机械环境，以指导机械适应性 |
Putra, V. L. |
PDF |
N/A |
Tuning mechanical milieux of tissue templates and their cellular inhabitants to guide mechanoadaptation |
| Protein2Text：为蛋白质序列提供丰富的描述 |
Dotan, E. |
PDF |
N/A |
Protein2Text: Providing Rich Descriptions for Protein Sequences |
| 癌症药物反应建模：蛋白质组学与转录组学的对比 |
Zheng, Z. |
PDF |
N/A |
Drug Response Modeling across Cancers: Proteomics vs. Transcriptomics |
| 预测和注释鸡基因组中的替代转录起始位点和启动子移位 |
Grushina, V. A. |
PDF |
N/A |
Prediction and annotation of alternative transcription starts and promoter shift in the chicken genome |
| 使用网络聚类算法进行细胞类型分化 |
Fatemi Nasrollahi, F. S. |
PDF |
N/A |
Cell Type Differentiation Using Network Clustering Algorithms |
| 重复扩增障碍中CRISPR/Cas9靶向纳米孔测序方法的比较分析 |
Benarroch, L. |
PDF |
N/A |
Comparative analysis of CRISPR/Cas9-targeted nanopore sequencing approaches in repeat expansion disorders |
| RIDDEN：从转录组数据中推断受体活性的数据驱动推理 |
Barsi, S. |
PDF |
N/A |
RIDDEN: Data-driven inference of receptor activity from transcriptomic data |
| GraphVelo 允许推断多模态单细胞速度和分子机制 |
Chen, Y. |
PDF |
N/A |
GraphVelo allows inference of multi-modal single cell velocities and molecular mechanisms |
| BindingGYM：一个大规模的突变数据集，旨在解析蛋白质-蛋白质相互作用 |
Lu, W. |
PDF |
N/A |
BindingGYM: A Large-Scale Mutational Dataset Toward Deciphering Protein-Protein Interactions |
| 用于生物组织定量光学特性和色团浓度图像的深度集成模型 |
Yan, B. |
PDF |
N/A |
Deep Ensemble Model for Quantitative Optical Property and Chromophore Concentration Images of Biological Tissues |
| 金复合物Auranofin使耐铂的上皮性卵巢癌细胞对顺铂敏感 |
Abdalbari, F. H. |
PDF |
N/A |
The gold complex auranofin sensitizes platinum resistant epithelial ovarian cancer cells to cisplatin |
| 鹦形目中高密度和低密度脂蛋白胆固醇的血清脂质参考区间及其与动脉粥样硬化和其他因素的关联 |
Janeczek, M. |
PDF |
N/A |
Serum lipid reference intervals of high-density and low-density lipoprotein cholesterols and their association with atherosclerosis and other factors in Psittaciformes |
| 苯代谢物通过激活热休克蛋白和Rho GTPase来增加血管通透性。 |
Zelko, I. N. |
PDF |
N/A |
Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases |
| 蛇毒金属蛋白酶主要负责某些非洲蝰蛇毒液的细胞毒性作用。 |
Bartlett, K. E. |
PDF |
N/A |
Snake venom metalloproteinases are predominantly responsible for the cytotoxic effects of certain African viper venoms |
| 肾上腺皮质癌细胞对氧化铁纳米颗粒的摄取 |
Challapalli, R. S. |
PDF |
N/A |
Adrenocortical Cancer Cell uptake of Iron Oxide Nanoparticles |
| ACKR3信号的淋巴激活调节缺血性心脏损伤后的淋巴反应。 |
Balint, L. |
PDF |
N/A |
Lymphatic activation of ACKR3 signaling regulates lymphatic response after ischemic heart injury. |
| At-RS31 调控剪接因子的层级交叉调节，并将选择性剪接与TOR-ABA途径整合 |
Koster, T. |
PDF |
N/A |
At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways |
| CAFE：一个综合性的网络应用程序，用于光谱流式细胞术中的高维度分析与可视化 |
Siam, M. H. B. |
PDF |
N/A |
CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry |
| 参考组织的同时多因素贝叶斯分析（SiMBA）在PET时间活动曲线数据中的实现 |
Matheson, G. J. |
PDF |
N/A |
A Reference Tissue Implementation of Simultaneous Multifactor Bayesian Analysis (SiMBA) of PET Time Activity Curve Data |
| 脑损伤后斑马鱼嗅觉系统的结构再生和功能恢复 |
Calvo-Ochoa, E. |
PDF |
N/A |
Structural regeneration and functional recovery of the olfactory system of zebrafish following brain injury |
| 亚精胺通过调节应激反应缓解抑郁 |
Mackert, S. |
PDF |
N/A |
Spermidine alleviates depression via control of the stress response |
| 小鼠方偏差：在规则修订模型中的审议决策揭示了小鼠中类似“我方”确认偏差的认知过程。 |
Stevens, C. |
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Mice-side bias: Deliberative decision making in a model of rule revision reveals 'myside' confirmation bias-like cognitive processes in mice. |
| 皮层动力学在快速步态启动中的作用，涉及不同的姿势需求 |
Giesbers, I. |
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N/A |
Cortical dynamics underlying initiation of rapid steps with contrasting postural demands |
| 快感不足？幻觉倾向对积极自我语音感觉反馈处理的影响 |
Duggirala, S. X. |
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N/A |
Not enough pleasure? Influence of hallucination proneness on sensory feedback processing of positive self-voice |
| 从子宫到摇篮：胎儿在子宫内的活动模式如何揭示出生后的睡眠行为 |
Markovic, A. |
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N/A |
From womb to crib: How fetal activity patterns in utero reveal postnatal sleep behavior |
| 规模多样性、丰度和能量：生物多样性动态的平衡理论 |
Storch, D. |
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N/A |
Scaling diversity, abundance and energy: the Equilibrium Theory of Biodiversity Dynamics |
| 利用贝叶斯分层模型结合声学遥测、生物学和环境数据评估溯河性鲑科鱼类的存活率 |
Munaweera, I. |
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N/A |
Estimating survival of an anadromous salmonid using Bayesian hierarchical models applied to acoustic telemetry, biological, and environmental data |
| 通过谱系学视角看幻影上位 |
Ignatieva, A. |
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N/A |
Phantom epistasis through the lens of genealogies |
| 环境诱导的精子sRNA变异与斑马鱼后代的基因表达和转座元件相关 |
Godden, A. M. |
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N/A |
Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring |
| 在更新世乳齿象的边缘种群中，气候驱动的扩散和物种形成反复发生。 |
Karpinski, E. |
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N/A |
Repeated climate-driven dispersal and speciation in peripheral populations of Pleistocene mastodons |
| 生活在不同气候带的北极熊亚种群之间转座子活性差异 |
Godden, A. M. |
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N/A |
Diverging transposon activity among polar bear sub-populations inhabiting different climate zones |
| 在Podospora anserina中，MAT近端区域的遗传分化并不足以抑制重组 |
Grognet, P. |
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N/A |
Genetic differentiation in the MAT-proximal region is not sufficient for suppressing recombination in Podospora anserina |
| 色素沉着与视网膜色素上皮厚度：一项研究眼内与眼外色素组织表型与基因型关系的研究。 |
Julian, T. H. |
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Pigmentation and retinal pigment epithelium thickness: a study of the phenotypic and genotypic relationships between ocular and extraocular pigmented tissues. |
| 一种模拟人类LDLR相关动脉粥样硬化的猫科动物模型 |
Hytonen, M. K. |
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N/A |
A feline model of human LDLR-related atherosclerosis |
| 大肠杆菌中补骨脂素-链间交联抗性的复杂发展需要AcrR失活、保留marbox序列以及MarA、SoxS或Rob全球调控因子中的一个。 |
Worley, T. K. |
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N/A |
The complex development of psoralen-interstrand crosslink resistance in Escherichia coli requires AcrR inactivation, retention of a marbox sequence, and one of three MarA, SoxS, or Rob global regulators |
| 功能基因组学验证PPARγ信号在肺动脉平滑肌细胞中的作用：对肺动脉高压治疗的启示 |
Su, R. |
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N/A |
Functional Genomics Validation of PPAR gamma Signalling in PASMCs: Therapeutic Implications for Pulmonary Arterial Hypertension |
| 埃及伊蚊全线粒体基因组分析揭示与沃尔巴克氏菌感染的关联 |
Gupta, B. |
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N/A |
Whole mitochondrial genome analysis of Aedes aegypti reveal association with Wolbachia infection |
| 预测多肽结构构象与AlphaFold2 |
Ille, A. M. |
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N/A |
Prediction of peptide structural conformations with AlphaFold2 |
| 使用混合数据集中的二维电导率概率分布进行遗传序列识别的机器学习框架 |
Wang, Y. |
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N/A |
A ML Framework for Genetic Sequence Identification using 2D Electrical Conductance Probability Distributions from Mixed Data Sets |
| GRU-SCANET：释放基于GRU的正弦捕获网络在精准命名实体识别中的潜力 |
Happi Happi, B. G. |
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N/A |
GRU-SCANET: Unleashing the Power of GRU-based Sinusoidal CApture Network for Precision-driven Named Entity Recognition |
| 体外β2肾上腺素受体刺激下BPH-1细胞的神经内分泌分化 |
PIGAT, N. |
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N/A |
In vitro neuroendocrine differentiation of BPH-1 cells under beta2 adrenergic receptor stimulation |
| 小鼠膀胱癌中多谱系肿瘤细胞群体的图谱绘制 |
Schrode, N. |
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N/A |
Mapping of Multilineage Tumor Cell Populations in Mouse Bladder Cancer |
| SUMO抑制加上CD40激动剂通过干扰素介导的巨噬细胞激活增加了抗肿瘤免疫原性 |
Li, K. Y. |
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SUMO Inhibition Plus CD40 Agonism Increases Anti-Tumor Immunogenicity Through Interferon Mediated Macrophage Activation |
| 在详细的皮层模型中，尖峰分类偏差和信息丢失 |
Laquitaine, S. |
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N/A |
Spike sorting biases and information loss in a detailed cortical model |
| TRPM7活性以依赖镁的方式驱动人类CD4 T细胞的激活和分化 |
Madlmayr, A. |
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TRPM7 activity drives human CD4 T-cell activation and differentiation in a magnesium dependent manner |
| 在组织工程平台上协同生成心脏驻留样巨噬细胞和心肌细胞成熟 |
Suku, M. |
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N/A |
Synergistic generation of cardiac resident-like macrophages and cardiomyocyte maturation in tissue engineered platforms |
| 破坏基底CXCR4寡聚体损害淋巴瘤中的致癌特性 |
Mobach, S. |
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N/A |
Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms |
| 建立可靠的小鼠三甲胺N-氧化物状态血液生物标志物：口服胆碱挑战、饮食胆碱和禁食条件的影响 |
Din, A. U. |
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N/A |
Establishing reliable blood biomarkers for trimethylamine N-oxide status in rodents: effects of oral choline challenge, dietary choline and fasting conditions |
| 将多样化的生物活性数据整合到化学检查器化合物宇宙中 |
Comajuncosa-Creus, A. |
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N/A |
Integration of diverse bioactivity data into the Chemical Checker compound universe |
| MerQuaCo：一种基于图像的空间转录组学质量控制计算工具 |
Martin, N. X. |
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N/A |
MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics |
| 布卡·德拉·伊纳和格罗塔·德尔·卡普里奥洛：对意大利中部两个晚期穆斯特文化遗址的新年代学、石器和动物群分析 |
Gennai, J. |
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N/A |
Buca della Iena and Grotta del Capriolo: new chronological, lithic, and faunal analyses of two late Mousterian sites in Central Italy |
| 果蝇中一种用于情境依赖的多模态信号传递的神经回路 |
Steinfath, E. |
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N/A |
A neural circuit for context-dependent multimodal signaling in Drosophila |
| lenacapavir通过一种主要机制实现对HIV-1成熟过程的高度有效抑制。 |
Huang, S.-W. |
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N/A |
The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir |
| 鱼精蛋白的抗真菌活性 |
Kumarasamy, A. |
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N/A |
Antifungal activity of protamine |
| 植物来源的代谢物与根际微生物群功能的相互作用增强了干旱胁迫耐受性 |
Kazarina, A. |
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N/A |
Interaction of plant-derived metabolites and rhizobiome functions enhances drought stress tolerance |
| 基质孔隙度与假体关节感染期间金黄色葡萄球菌生物膜的存活有关。 |
Bhattacharya, M. |
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N/A |
Matrix porosity is associated with Staphylococcus aureus biofilm survival during prosthetic joint infection |
| 在B族链球菌中进行的CRISPRi文库筛选鉴定出表面免疫原性蛋白（Sip）作为多种宿主相互作用的中介因子。 |
Firestone, K. |
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N/A |
A CRISPRi Library Screen in Group B Streptococcus Identifies Surface Immunogenic Protein (Sip) as a Mediator of Multiple Host Interactions |
| 施肥对草地食物链中的微生物群落产生影响 |
Jetter, K. |
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N/A |
Fertilization impacts microbiomes along the grassland trophic chain |
| 敲除仅在排泄腺细胞中表达的所有线虫特异性NSPC基因，会导致转录组特征表明胰岛素信号传导受到影响。 |
Mackiewicz, Z. |
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N/A |
Knockout of all nematode-specific NSPC genes expressed exclusively in the excretory gland cell results in transcriptomic signatures indicating an affected insulin signaling |
| PER2蛋白表达减少导致β1-AA诱导的心脏自噬节律紊乱 |
Li, P. |
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N/A |
Reduced expression of PER2 protein contrbutes to β1-AA induced cardiac autophagy rhythm disorder |
| 不同相互作用类型的生态网络在生物地理尺度上具有模块性，并且高度依赖于采样强度。 |
Garcia-Callejas, D. |
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N/A |
Ecological networks across interaction types are modular and highly driven by sampling intensity at biogeographical scales |
| 蛋白质进化中的波动与可预测性极限 |
Rossi, S. |
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N/A |
Fluctuations and the limit of predictability in protein evolution |
| 一般人群中的亲代间基因转换：一种新的杂合性丧失机制 |
Toratani, J. |
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N/A |
Interparental Gene Conversion in General Population: A Novel Mechanism For Loss of Heterozygosity |
| 一氧化氮通过Rab5的S-亚硝基化调节吞噬作用 |
Hagiwara, M. |
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N/A |
Nitric oxide regulates phagocytosis through S-nitrosylation of Rab5 |
| 基于大环降解剂BTR2004对CUL3KLHL20驱动的BET家族BRD蛋白靶向降解的时间和空间特性研究 |
Yeh, J. |
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N/A |
Temporal and Spatial Characterization of CUL3KLHL20-driven Targeted Degradation of BET family, BRD Proteins by the Macrocycle-based Degrader BTR2004 |
| 设计白细胞介素-21模拟物的强大抗癌活性 |
Chun, J.-H. |
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N/A |
Potent antitumor activity of a designed interleukin-21 mimic |
| 用于冷冻电镜和冷冻电子断层扫描中方向估计的贝叶斯视角 |
Xu, S. |
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N/A |
Bayesian Perspective for Orientation Estimation in Cryo-EM and Cryo-ET |
| 由NKX2-1调控的表观遗传重塑和三维染色质重构推动神经内分泌前列腺癌的发展。 |
Lu, X. |
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N/A |
Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancer |
| 发现新型选择性GPR17拮抗剂作为开发糖尿病和肥胖症新治疗策略的药理工具 |
Zhu, H. |
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N/A |
Discovery of Novel and Selective GPR17 Antagonists as Pharmacological Tools for Developing New Therapeutic Strategies in Diabetes and Obesity |
| 小麦白粉病菌（Zymoseptoria tritici）的隐匿感染是通过阶段特异性下调β-葡聚糖酶来实现的。 |
Rebaque, D. |
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N/A |
Zymoseptoria tritici stealth infection is facilitated by stage-specific down-regulation of a β-glucanase |
| 陆生植物中果胶裂解酶样基因的进化及其在寄生植物吸器形成中的作用 |
Zhang, H. |
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N/A |
The evolution of pectate lyase-like genes across land plants, and their roles in haustorium formation in parasitic plants |
| 一步法生物催化级联反应从醛或羧酸制备多种L-苯丙氨酸衍生物 |
Anderson, S. R. |
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N/A |
A One-Pot Biocatalytic Cascade to Access Diverse L-Phenylalanine Derivatives from Aldehydes or Carboxylic Acids |
| MCSPACE：从高通量共定位数据推断微生物组的时空动态 |
Uppal, G. |
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N/A |
MCSPACE: inferring microbiome spatiotemporal dynamics from high-throughput co-localization data |
| 家庭环境中的病原体和抗菌药物耐药基因：孟加拉国农村土壤地板和牛粪研究 |
Nguyen, A. T. |
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N/A |
Pathogens and Antimicrobial Resistance Genes in Household Environments: A Study of Soil Floors and Cow Dung in Rural Bangladesh |
| 全基因组分析大肠杆菌对次硫氰酸盐胁迫的响应，揭示RclB和RclC可能降低细胞膜通透性的作用 |
Meredith, J. D. |
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N/A |
Genome-wide characterization of hypothiocyanite stress response of Escherichia coli reveals a potential role for RclB and RclC in lowering cell envelope permeability |
| 通过HIV-1编码的反义转录本实现表观遗传沉默及潜伏逆转的阻断 |
Li, R. |
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N/A |
Epigenetic silencing and blockade of latency reversal by an HIV-1 encoded antisense transcript |
| 成年蜂王食用花粉和花蜜。 |
St. Clair, A. |
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N/A |
Adult honey bee queens consume pollen and nectar |