| 个体间在皮层组织的感觉运动-关联轴上的差异具有独特的遗传基础 |
Bignardi, G. |
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Distinct genetic underpinnings of inter-individual differences in the sensorimotor-association axis of cortical organisation |
| RNA结合蛋白IMP1/ZBP1驱动Actb mRNA在微胶质细胞外周突起中的定位和局部翻译，并介导形态变化、运动性和吞噬作用以响应炎症 |
Imaz-Iruretagoyena, J. |
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RNA binding protein IMP1/ZBP1 drives Actb mRNA localization and local translation in microglial peripheral processes and mediates morphological changes, motility and phagocytosis in response to inflammation |
| 保守的3'茎环结构使我们能够在宏基因组中全面分析细菌转录终止，无论是否依赖Rho因子 |
Jin, Y. |
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Conserved 3' Stem-Loop Structures Enable Comprehensive Analysis of Bacterial Transcription Termination in Metagenomes, Regardless of Rho Factor Dependency |
| 通过快速突触变化实现的简单句法规则 |
Sun, L. |
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Simple syntactic rules through rapid synaptic changes |
| miRTarDS：利用Sentence-BERT从预测数据库中高精度提炼蛋白质水平的微RNA目标相互作用 |
Chen, B. |
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miRTarDS: High-Accuracy Refining Protein-level MicroRNA Target Interactions from Prediction Databases Using Sentence-BERT |
| 微囊藻中标记基因及细胞内无定形碳酸钙生物矿化候选基因表达的昼夜变化 |
Bruley, A. |
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Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis |
| 值班爸爸：斑胸草雀首次孵卵记录 |
Scheiber, I. B. R. |
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Dads on duty: First account of nest sitting in barnacle ganders |
| 谱系限制的机制基础 |
Wu, B. |
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Mechanistic basis of lineage restriction |
| 每月对大型藻类的调查显示，城市潮间带区域存在着一个多样且动态的生物群落。 |
Schenk, S. |
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Monthly macroalgal surveys reveal a diverse and dynamic community in an urban intertidal zone |
| 淀粉样前体蛋白（Amyloid Beta Precursor Protein）在短命的蓝绿光鳉鱼（Nothobranchius furzeri）中促进了脑衰老和学习能力的下降。 |
de Bakker, D. E. M. |
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Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri) |
| 对蝾螈Y染色体更替的鉴定未能支持Triturus平衡致死系统起源于性染色体 |
France, J. M. |
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Identification of Y-chromosome turnover in newts fails to support a sex chromosome origin for the Triturus balanced lethal system |
| 在胚胎关键期，线粒体活性氧和HIF1-α信号的保守作用指导了后续神经系统发育。 |
Sobrid-Camean, D. |
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Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development |
| 内耳神经元脱层的时间决定了它们的地形和目标神经支配 |
Saini, S. S. J. S. |
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Timing of delamination of inner ear neurons specifies their topography and target innervation |
| 细菌计数时连续稀释过程中样本体积传递与传递次数之间的权衡 |
Jain, M. |
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Trade-off between sample volume passaged and number of passages involved during serial dilution for bacterial enumeration |
| 人巨细胞病毒全病毒蛋白质组学揭示gpUL141是一种病毒颗粒成分，通过调节包膜糖蛋白组成以抵御体液免疫 |
Bentley, K. |
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Whole Virion Proteomics of HCMV Reveals that gpUL141 is a Virion Component that Regulates Envelope Glycoprotein Composition to Protect Against Humoral Immunity |
| 葡萄糖感应ChREBP蛋白在糖尿病视网膜病变发病机制中的作用 |
Starr, C. R. |
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Glucose-Sensing ChREBP Protein in the Pathogenesis of Diabetic Retinopathy |
| 自愿行动能增强感官预测，并促进对相关感官刺激的神经处理。 |
Ody, E. |
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Voluntary action sharpens sensory prediction and facilitates neural processing of contingent sensory stimuli |
| 个性预测在新栖息地中的扩散和定居——一项中尺度实验 |
Gismann, J. |
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Personality predicts dispersal and settlement in a novel habitat - a mesocosm experiment |
| 北极星：人类群体中扩展单倍型纯合性推断的祖先和衍生多态等位基因的极化。 |
Lisi, A. |
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Polaris: Polarization of ancestral and derived polymorphic alleles for inferences of extended haplotype homozygosity in human populations. |
| 腹侧被盖区GABA神经元整合正负效价 |
Stelzner, M. E. |
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Ventral tegmental area GABA neurons integrate positive and negative valence |
| GABA能杏仁核神经元中的HCN1通道支撑着偏向雄性的攻击行为 |
Li, K. |
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HCN1 channels in GABAergic amygdalar neurons underpin male-biased aggressive behaviors |
| 通过磁共振成像组织学表征的黑猩猩大脑寿命轨迹 |
Lipp, I. |
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Lifespan trajectory of chimpanzee brains characterized by magnetic resonance imaging histology |
| Pcdh15在内耳毛细胞内在极性发育中的作用 |
Kaushik, R. |
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Role Of Pcdh15 In The Development Of Intrinsic Polarity Of Inner Ear Hair Cells |
| 空间单细胞细胞器组学揭示了营养依赖的肝细胞异质性，并预测了体内的病理生理状态 |
Hillsley, A. |
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Spatial single-cell Organellomics reveals nutrient dependent hepatocyteheterogeneity and predicts pathophysiological status in vivo |
| 单细胞分析揭示了B细胞发育的多方面特征，以及与年龄相关的B细胞亚群 |
Yang, X. |
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Single-cell analysis reveals multi-faceted features of B cell development together with age-associated B cell subpopulations |
| 高尔基体中谷胱甘肽氧化还原状态的表征 |
Miro-Vinyals, C. |
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Characterization of the Glutathione Redox State in the Golgi Apparatus |
| 储存操作的钙离子进入参与了肺血管内皮细胞中的内皮间质转化 |
Babicheva, A. |
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Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells |
| FNBP4介导的非中心体形成蛋白FMN1在肌动蛋白细胞骨架动态调控中的机制性见解 |
Das, S. |
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Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics |
| MuSpAn：一个多尺度空间分析工具箱 |
Bull, J. A. |
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MuSpAn: A Toolbox for Multiscale Spatial Analysis |
| SubCell: 用于显微镜的视觉基础模型捕捉单细胞生物学 |
Gupta, A. |
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SubCell: Vision foundation models for microscopycapture single-cell biology |
| 从卵母细胞中分离和操控减数分裂纺锤体揭示了在不对称分裂过程中由牵引力调控的迁移 |
Liu, N. |
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Isolation and manipulation of meiotic spindles from mouse oocytes reveals migration regulated by pulling force during asymmetric division |
| 染色质压缩遵循幂律缩放规律，从间期到有丝分裂期间，其与细胞大小成比例变化。 |
Stockinger, P. |
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Chromatin Compaction Follows a Power Law Scaling with Cell Size from Interphase Through Mitosis |
| 超分辨成像揭示了CD81微区在调节Jurkat T细胞微绒毛膜信号传导中的空间组织 |
Ramseier, N. |
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Superresolution Imaging Reveals the Spatial Organization of CD81 Microdomains in Regulating Membrane Signaling on Jurkat T Cell Microvilli |
| FAK活性通过VEGFR2-Cbl-NF-κB信号通路加剧了扰流介导的动脉粥样硬化。 |
Lim, S. |
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FAK activity exacerbates disturbed flow-mediated atherosclerosis via VEGFR2-Cbl-NF-κB signaling. |
| 用于面部修复、再生和抗衰老的外泌体：不同商业产品之间的比较 |
Salvaggio, A. |
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Exosomes for facial repair, regeneration and rejuvenation: comparison between different commercial products |
| 间充质干细胞/基质细胞向CD45+巨噬细胞样细胞的分化：拓展对MSC可塑性的认识 |
Rusch, R. M. |
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Differentiation of Mesenchymal Stem/ Stromal Cells into CD45+ Macrophage-like Cells: Expanding Insights into MSC Plasticity |
| 肌修复过程中肌营养不良蛋白表达的时空分析 |
Hildyard, J. C. W. |
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Spatiotemporal analysis of dystrophin expression during muscle repair |
| 普利帕斯汀是枯草芽孢杆菌在对抗镰刀菌属时共享的一种有益物质。 |
Stannius, R. O. |
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Plipastatin is a shared good by Bacillus subtilis during combating Fusarium spp. |
| 细胞内RNA环状结构水平升高会抑制抗病毒反应。 |
Duan, C. |
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Elevated levels of intracellular RNA lariats suppress the antiviral response |
| 去组蛋白修饰的Cas12a增强了单细胞CRISPR筛选 |
Snetkova, V. |
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Degron-modified Cas12a enhances single-cell CRISPR screening |
| 人类遗传变异揭示FCRL3是淋巴细胞的鼠疫耶尔森菌受体 |
Keener, R. |
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Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis |
| Leucine Rich Repeat Kinase 2的Ras of Complex Proteins/GTPase结构域中的功能丧失性编码变异 |
Butterfield, S. |
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Loss-of-function coding variants in the Ras of Complex Proteins/GTPase domain of Leucine Rich Repeat Kinase 2 |
| 利用DMS MaP-Seq技术概念化核糖体mRNA解旋 |
Kellenberger, P. |
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Conceptualizing Ribosomal mRNA Unwinding Utilizing DMS MaP-Seq |
| 细胞修饰tRNALys3的氨酰化的人类赖氨酰-tRNA合成酶的结构基础 |
Devarkar, S. C. |
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Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase |
| 评估HGNC中人类非编码RNA命名的稳健性 |
Prasetyo, N. K. |
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Assessing the robustness of human ncRNA notation at HGNC |
| 基于HSV-1基因组维持的HEK293细胞开发EASY-HSV（高效且简单的高产单纯疱疹病毒载体）系统 |
Maeda, F. |
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Development of the EASY-HSV (Efficient And Simple high-Yield Herpes Simplex virus Vector) system based on HSV-1 genome-maintaining HEK293 cells |
| 脂质纳米颗粒递送mRNA逆转溶酶体酸性脂肪酶缺乏症的病理发生于临床前模型中 |
Zadory, M. |
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Lipid-based nanoparticles deliver mRNA to reverse the pathogenesis of lysosomal acid lipase deficiency in a preclinical model |
| OMAnnotator：一种构建注释共识基因组序列的新方法 |
Bates, S. |
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OMAnnotator: a novel approach to building an annotated consensus genome sequence |
| ProkBERT PhaStyle：利用预训练基因组语言模型进行准确的噬菌体生活方式预测 |
Juhasz, J. |
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ProkBERT PhaStyle: Accurate Phage Lifestyle Prediction with Pretrained Genomic Language Models |
| 体外调节基于肌动蛋白的活性组装的收缩性和变形模式：从二维活性网络到液晶液滴 |
Stam, S. |
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Tuning the contractility and deformation modes of active actin-based assemblies in vitro: from 2D active networks to liquid crystal drops |
| CCR7和细胞粘附分子在鸡胚发育中对B细胞迁移至法氏囊的调控 |
Brunner, M. |
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Regulation of B cell migration to the Bursa of Fabricius by CCR7 and cell adhesion molecules in chicken embryonic development |
| 源自肉桂皮提取物的纳米杀菌剂：植物化学成分分析及其对水稻细菌性穗枯病的抗菌功效 |
Alsutan, Q. M. |
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Nanobactericides Derived from Cinnamon Bark Extract: Phytochemical Profiling and Antibacterial Efficacy Against Bacterial Panicle Blight in Rice |
| 根际土壤微生物类群的活性可以预测根系定殖的成功与否。 |
Harris, J. E. |
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The activity of soil microbial taxa in the rhizosphere predicts the success of root colonization |
| 人诱导多能干细胞衍生的肌肉细胞作为研究EDMD1发病机制的新模型。 |
Lisowska, M. |
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Human iPSCs-derived muscle cells as a new model for investigation of EDMD1 pathogenesis. |
| 一码多用：用于修复热点外显子剪接突变的反义寡核苷酸 |
Duan, C. |
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One-Size-Fits-Many: Antisense oligonucleotides for rescuing splicing mutations in hotspot exons |
| 透明质酸与新兴组织力学协同调控指尖再生 |
Mui, B. W. H. |
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Hyaluronic Acid and Emergent Tissue Mechanics Orchestrate Digit Tip Regeneration |
| 没有证据表明蝴蝶的蛋白质组组成与其实际的温度极限和饮食生态位宽度有关。 |
Caron, F. |
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No evidence that proteome composition is associated with realised thermal limit and dietary niche breadth in butterflies |
| 亚致死剂量的农药暴露会降低有益传粉者的交配率并扰乱其化学信号传递。 |
Derstine, N. |
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Sublethal pesticide exposure decreases mating and disrupts chemical signaling in a beneficial pollinator |
| 减数分裂性染色体失活：果蝇属中的保守性 |
Avelino, C. C. |
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Meiotic Sex Chromosome Inactivation: conservation across the Drosophila genus |
| 发现5mC特异性脱氨酶及其在碱基分辨率下超灵敏直接测序甲基化位点的应用。 |
Yang, W. |
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The discovery of 5mC-selective deaminases and their application to ultra-sensitive direct sequencing of methylated sites at base resolution. |
| SpatioMark：量化空间邻近性对细胞表型的影响 |
Iyengar, S. S. |
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SpatioMark: Quantifying the impact of spatial proximity on cell phenotype |
| 建模并预测单细胞多基因扰动响应：scLAMBDA |
Wang, G. |
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Modeling and predicting single-cell multi-gene perturbation responses with scLAMBDA |
| CASSIA能够在单细胞RNA测序数据中进行稳健、自动的细胞注释。 |
Xie, E. |
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CASSIA allows for robust, automated cell annotation in single-cell RNA-sequencing data |
| 果蝇连接组中的并行与汇聚多感官级联 |
Betzel, R. F. |
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Parallel and converging multisensory cascades in the Drosophila connectome |
| 利用FoxP2区分鸣禽发声学习中的直接和间接基底神经节通路 |
Jagannathan, A. |
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Using FoxP2 to Distinguish Direct and Indirect Basal Ganglia Pathways for Vocal Learning in Songbirds |