| 混合交配系统中的中性遗传多样性 |
Uyenoyama, M. K. |
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N/A |
Neutral genetic diversity in mixed mating systems |
| 早期生活压力引发与恐惧泛化相关的持续性星形胶质细胞功能障碍。 |
Guayasamin, M. |
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N/A |
Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation |
| 撤回：增强突变热点预测：原子波动的作用 |
Martis, E. A. F. |
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N/A |
WITHDRAWN: Enhancing Mutational Hotspot Predictions: The Role of Atomic Fluctuations |
| 使用在横截面数据上预训练的规范模型来评估神经影像数据中的个体内部纵向变化 |
Rehak Buckova, B. |
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N/A |
Using normative models pre-trained on cross-sectional data to evaluate intra-individual longitudinal changes in neuroimaging data |
| 细胞膜通过胆固醇不对称性维持磷脂不平衡 |
Doktorova, M. |
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N/A |
Cell Membranes Sustain Phospholipid Imbalance Via Cholesterol Asymmetry |
| QInfoMating：性选择与选型交配估计软件 |
Carvajal-Rodriguez, A. |
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N/A |
QInfoMating: Sexual Selection and Assortative Mating Estimation Software |
| HERV的激活将ME/CFS与纤维肌痛区分开来，同时定义了一个新的疾病分类实体。 |
Gimenez-Orenga, K. |
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N/A |
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity |
| 基于文库的单细胞RNA测序中辅助性T细胞亚群的映射与时间追踪 |
Lukyanov, D. K. |
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N/A |
Repertoire-based mapping and time-tracking of helper T cell subsets in scRNA-Seq |
| 睾酮诱导的精囊上皮细胞代谢变化会改变血浆成分，从而增强精子生育能力。 |
Yamanaka, T. |
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N/A |
Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility |
| 来自辐射杂交和CRISPRi的互补人类基因相互作用图谱 |
Smith, D. J. |
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N/A |
Complementary human gene interaction maps from radiation hybrids and CRISPRi |
| 肾小球弹性与基因表达模式定义了Alport肾病的两个阶段 |
Yoon, J. |
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N/A |
Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy |
| MdfA是一种新型的ClpC适配蛋白，在枯草芽孢杆菌孢子的发育过程中发挥作用。 |
Massoni, S. C. |
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N/A |
MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore |
| 特定PIP2亚型组成的识别触发了别构控制机制，该机制用于选择性膜定位内质网固醇转运蛋白StarD4的货物装载和释放功能。 |
Xie, H. |
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N/A |
Recognition of specific PIP2-subtype composition triggers the allosteric control mechanism for selective membrane targeting of cargo loading and release functions of the intracellular sterol transporter StarD4 |
| 在羊膜动物原肠胚形成过程中，左右组织者形成之前，双侧细胞流动呈现出不对称性。 |
Asai, R. |
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N/A |
Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation |
| 视觉的第一个突触处存在一种异质性群体编码 |
Herzog, T. |
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N/A |
A heterogeneous population code at the first synapse of vision |
| 通过生成式深度学习对高度动态蛋白质的构象集合进行采样 |
Ruzmetov, T. |
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N/A |
Sampling Conformational Ensembles of Highly Dynamic Proteins via Generative Deep Learning |
| 将翻译后的数字数据编码到哺乳动物细胞群体的基因组中 |
Callisto, A. |
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N/A |
Post-translational digital data encoding into the genomes of mammalian cell populations |
| 从解剖学角度来看，大脑皮层通过慢速（1-8Hz）和快速（70-120Hz）振荡活动对音乐和语言进行不同的追踪。 |
Osorio, S. |
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N/A |
Anatomically distinct cortical tracking of music and speech by slow (1-8Hz) and fast (70-120Hz) oscillatory activity |
| 在小麦根际中，假单胞菌的分类和功能微多样性是因品种而异的，并且与抗病性特征和根直径有关。 |
Herms, C. H. |
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N/A |
Pseudomonas taxonomic and functional microdiversity in the wheat rhizosphere is cultivar-dependent and links to disease resistance profile and root diameter |
| Oviductin决定了哺乳动物透明带（zona pellucida）的种属特异性。 |
de la Fuente, D. |
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N/A |
Oviductin sets the species-specificity of the mammalian zona pellucida |
| 一个动力学简单行走模型修正了恢复率的定义：人类行走在大支撑阶段与摆动运动有显著偏离 |
Hosseini-Yazdi, S.-S. |
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N/A |
A Powered Simple Walking Model Modifies the Rate of Recovery Definition: Human Walking Deviates Drastically from Pendular Motion During the Double Support Phase |
| 通过非自主元件的调控来维持长期的可转座元件活性 |
Omole, A. D. |
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N/A |
Maintenance of long-term transposable element activity through regulation by nonautonomous elements |
| 天蝎座：增强嵌入以改善DNA序列的下游分析 |
Refahi, M. |
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N/A |
Scorpio : Enhancing Embeddings to Improve Downstream Analysis of DNA sequences |
| 质心工作分析估计不同行走条件下的首选步行速度 |
Hosseini-Yazdi, S.-S. |
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N/A |
Center of Mass Work Analysis Estimates Preferred Walking Speeds for Varying Walking Conditions |
| 解耦冠状病毒Nsp1的功能角色 |
Baeumlin, E. |
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N/A |
Uncoupling the functional roles of Coronavirus Nsp1 |
| 定期更新的基准数据集，用于对AlphaFold应用进行统计正确的评估 |
Dobson, L. |
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N/A |
Regularly updated benchmark sets for statistically correct evaluations of AlphaFold applications |
| 重新审视脑脊液的等效光学特性以提高基于扩散的大脑建模精度 |
Lewis, A. |
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N/A |
Revisiting equivalent optical properties for cerebrospinal fluid to improve diffusion-based modeling accuracy in the brain |
| 碳酸酐酶抑制剂可预防脑淀粉样变性模型中无症状的毛细血管血流紊乱。 |
Gutierrez-Jimenez, E. |
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N/A |
Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis |
| 功能失调的机械传导调节了PIK3CA驱动的血管畸形的进展 |
Aw, W. Y. |
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N/A |
Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations |
| 使用深度学习在冷冻电镜和X射线图中识别配体 |
Karolczak, J. |
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N/A |
Ligand Identification in CryoEM and X-ray Maps Using Deep Learning |
| 响应多样性是复杂食物网中时间稳定性的主要驱动力。 |
Danet, A. |
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N/A |
Response diversity is a major driver of temporal stability in complex food webs |
| 高数据率大分子晶体学（HDRMX）的大规模压缩：对衍射数据及后续结构分析的影响 |
Bernstein, H. J. |
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N/A |
Massive Compression for High Data Rate Macromolecular Crystallography (HDRMX): Impact on Diffraction Data and Subsequent Structural Analysis |
| 物体非刚性各向异性：皮层各向异性对高级知觉的影响 |
Maruya, A. |
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N/A |
Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy |
| 运动学习利用协调的低频皮层-基底神经节活动来优化帕金森病患者运动准备 |
Presbrey, K. N. |
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N/A |
Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson's Disease |
| 利用蚂蚁共生体制作酸奶揭示了用于食品发酵的细菌、酸和酶。 |
Sinotte, V. M. |
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N/A |
Making yogurt with the ant holobiont uncovers bacteria, acids, and enzymes for food fermentation |
| 使用静息态fMRI的因果关系映射揭示了精神分裂症患者的高活动性和低连接性 |
Tahir, A. |
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N/A |
Causality Mapping Using Resting-state fMRI Reveals Hyperactivity and Hypoconnectivity in Schizophrenia Patients |
| 抑制性可塑性调控中时间精度与效应幅度之间的权衡决定了学习表征的可分离性。 |
Rubisch, P. |
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N/A |
The trade-off between temporal precision and effect amplitude of inhibitory plasticity regulation determines separability of learned representations |
| 在营养生长期暴露于高pH胁迫下的豌豆中的转录重编程与微生物群动态 |
Thapa, A. |
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N/A |
Transcriptional reprogramming and microbiome dynamics in garden pea exposed to high pH stress during vegetative stage |
| 在感染猿猴免疫缺陷病毒（SIV）的恒河猴中，大麻素能够改变基底神经节的miRNA m6A甲基化谱，使其趋向于抗炎表型。 |
Okeoma, C. M. |
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N/A |
Cannabinoids shift the basal ganglia miRNA m6A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques |
| 鉴定和靶向气道上皮细胞中SARS-CoV-2-宿主相互作用的调节因子。 |
Dirvin, B. G. |
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N/A |
Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium. |
| 在嗜盐碱杆菌（Haloferax volcanii）的生长周期中，古菌微管蛋白样蛋白CetZ1和CetZ2对细胞形态具有相反的影响。 |
Brown, H. J. |
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N/A |
Archaeal tubulin-like proteins CetZ1 and CetZ2 have opposing effects on cell morphology during the growth cycle of Haloferax volcanii |
| 全小鼠肾小球纳米级光学成像、重建与空间分析 |
Ali, A. |
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N/A |
Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse Glomeruli |
| Kauffman模型中闭合与开放式进化之间因果关系的证据 |
Faggian, M. F. |
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N/A |
Evidence of causality between Closure and Open-Ended Evolution in the Kauffman model |
| 皮质层次结构中神经编码的变化：从稀有的类别性到始终的高维度 |
Posani, L. |
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N/A |
Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy |
| 卵巢生殖干细胞的去分化是依赖于细胞突的。 |
Sutcliffe, C. |
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N/A |
Ovarian germline stem cell dedifferentiation is cytoneme-dependent |
| 侧孢曲霉：一种在日本新出现的隐匿性曲霉病病原体 |
Shibata, S. |
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N/A |
Aspergillus latus: a cryptic causative agent of aspergillosis emerging in Japan |
| 在高维数据空间中，是使用更多的潜在变量还是更少的潜在变量？这就是问题所在。 |
Vaccari, F. E. |
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N/A |
More or fewer latent variables in the high-dimensional data space? That is the question |
| CAFE：一种集成式网络应用程序，用于光谱流式细胞术中的高维数据分析与可视化 |
Siam, M. H. B. |
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N/A |
CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry |
| 自发脑活动背后的神经受体和转运蛋白 |
Nakuci, J. |
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N/A |
The neuroreceptors and transporters underlying spontaneous brain activity |
| 一种心血管-肾脏-代谢综合征的小鼠模型显示，在缺血的后肢中，肢体功能受损。 |
Chitalia, V. |
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N/A |
A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limb |
| 元预测扩展了人类大脑皮层和皮层下区域的奖励学习机制。 |
Shin, J. |
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N/A |
Meta-prediction extends human cortical and subcortical reward learning |
| 重复节奏模式有助于音乐节拍的神经表征 |
Coulon, E. |
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N/A |
Repetition of Rhythmic Patterns Fosters Neural Representation of Musical Meter |
| 将人类基因组演化的历程进行划分 |
Pagani, L. |
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N/A |
Partitioning the genomic journey to becoming Homo sapiens |
| CCNB1IP1顺式调控的进化推动了灵长类动物皮层大小和折叠程度的逐渐增加 |
Hu, T. |
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N/A |
Cis-Regulatory Evolution of CCNB1IP1 Driving Gradual Increase of Cortical Size and Folding in primates |
| 超越二分法：大鼠超声波发声的多样性 |
Wada, R. |
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N/A |
Beyond dichotomy: diversity of rat's ultrasonic vocalizations |
| 人类对声音而非触觉节奏的行为相关分段神经表征 |
Lenoir, C. |
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N/A |
Behavior-relevant periodized neural representation of acoustic but not tactile rhythm in humans |
| 与帕金森病相关的Pink1缺失会破坏包裹性胶质细胞中的囊泡运输，导致多巴胺能神经元突触丧失。 |
Ghezzi, L. |
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N/A |
Parkinson's disease-associated Pink1 loss disrupts vesicle trafficking in ensheathing glia causing dopaminergic neuron synapse loss |
| 基于PDMS的微流控芯片组件的时间分辨冷冻电镜（TRCEM）样品制备 |
Feng, X. |
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N/A |
Time-resolved cryo-EM (TRCEM) sample preparation using a PDMS-based microfluidic chip assembly |
| 通过冷冻电镜揭示的自然华丽的仅由RNA组成的复合物 |
Kretsch, R. C. |
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N/A |
Naturally ornate RNA-only complexes revealed by cryo-EM |
| 利用淋巴结探寻者64Cu标记的革兰氏阴性菌外泌体进行脑脊液淋巴引流PET成像 |
Kim, K. |
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N/A |
Lymphatic drainage of cerebrospinal fluid using lymph node seeker 64Cu-labeled Gram-negative bacterial extracellular vesicles PET |
| mTOR信号通路通过S6K1-RhoA和aPKC-Lgl2轴调控上皮细胞顶端突起的形成。 |
Sen, S. |
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N/A |
mTOR signaling governs the formation of epithelial apical projection via S6K1-RhoA and aPKC-Lgl2 axes |
| 生成用于研究精子中线粒体的转基因小鼠模型 |
Sarkar, H. |
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N/A |
Generation of a Transgenic Mouse Model for Investigating Mitochondria in Sperm |
| 通过联合过表达筛选，我们发现PIPPI是一种与内质网应激反应相关的新型微蛋白。 |
Lafranchi, L. |
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N/A |
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response |
| 细胞体积调控培养的人表皮角质形成细胞的终末分化 |
Watt, F. M. |
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N/A |
Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes |
| 人类白细胞中细胞类型特异性的自噬 |
Dang, L. |
PDF |
N/A |
Cell-type specific autophagy in human leukocytes |
| 微纤维模板孔凝胶生物墨水实现管状界面及微血管化，直至3D生物打印的基本构建单元 |
Guo, Y. |
PDF |
N/A |
Microfiber-Templated Porogel Bioinks Enable Tubular Interfaces and Microvascularization Down to the Building Blocks for 3D Bioprinting |
| 脂质的恒定pH分子动力学模拟 |
Trollmann, M. F. W. |
PDF |
N/A |
Constant-pH MD Simulations of Lipids |
| 人CFTR开放状态的结构和氯离子传导特性 |
Zeng, Z. W. |
PDF |
N/A |
Structure and Cl-Conductance Properties of the Open State of Human CFTR |
| TRIM5α PRYSPRY结构域与HIV衣壳无序相互作用界面的全原子视角 |
Haas-Neill, L. |
PDF |
N/A |
An all-atom view into the disordered interaction interface of the TRIM5α PRYSPRY domain and the HIV capsid |
| 神经回路机制在支配特质与社会竞争中的作用 |
Yan, H. |
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N/A |
Neural Circuit Mechanisms Underlying Dominance Traits and Social Competition |
| T细胞白血病中LMO2的降解会导致转录复合物伙伴的连带破坏以及LMO2依赖的细胞凋亡。 |
Sereesongsaeng, N. |
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N/A |
Degradation of LMO2 in T cell leukaemia causes collateral breakdown of transcription complex partners and LMO2-dependent apoptosis |
| 使用生物发光共振能量转移技术检测7TM受体的基础性和配体依赖性Gi导向活性的关键策略 |
Endzhievskaya, S. |
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N/A |
Essential strategies for the detection of constitutive and ligand-dependent Gi-directed activity of 7TM receptors using bioluminescence resonance energy transfer |
| 血管抑制素是由肾素-血管紧张素系统产生的。 |
Nunez, F. F. |
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N/A |
Vasoinhibin is Generated by the Renin-Angiotensin System |
| 微血管保护和心肌细胞增生是先天性心脏病相关肺动脉高压中右心室适应性发育的基础。 |
Smith, M. A. |
PDF |
N/A |
Microvascular preservation and cardiomyocyte hyperplasia underlie adaptive right ventricular development in congenital heart disease-associated pulmonary arterial hypertension |
| 基于先天适应性的早期运动训练的共享与独特适应性 |
Sadler, D. G. |
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N/A |
Shared and distinct adaptations to early-life exercise training based on inborn fitness |
| 转录组与代谢的综合分析揭示了氧化还原稳态在羊草低光和盐复合胁迫中的功能作用 |
Qu, M. |
PDF |
N/A |
Integrative analysis of transcriptome and metabolism reveals functional roles of redox homeostasis in low light and salt combined stress in Leymus chinensis |
| 利用INSIGHT技术在体内揭示扩散性胶质母细胞瘤细胞的信号网络 |
Ahn, R. |
PDF |
N/A |
Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT |
| FTO（脂肪量和肥胖相关蛋白）缺乏会加重与年龄相关的抑郁样行为和认知功能障碍。 |
Li, M. |
PDF |
N/A |
FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment |
| 自上而下的注意力和阿尔茨海默病的病理影响在学习过程中对皮层的选择性，影响老年人的情景记忆。 |
Sheng, J. |
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N/A |
Top-down attention and Alzheimer's pathology impact cortical selectivity during learning,influencing episodic memory in older adults |
| 活体中感觉轴突的口径在空间和时间上都有变化，并受细胞微环境的影响。 |
Ching, K. |
PDF |
N/A |
Caliber of sensory axons in vivo varies spatially and temporally and is influenced by the cellular microenvironment |
| 抑制性连接的空间约束对尖峰网络中临界性动态发展的影响 |
Kern, F. B. |
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N/A |
Effects of Spatial Constraints of Inhibitory Connectivity on the Dynamical Development of Criticality in Spiking Networks |
| 年龄相关的糖萼重塑驱动T细胞耗竭 |
Zhang, H. |
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N/A |
Age-related remodeling of the glycocalyx drives T cell exhaustion |
| 一种人畜共患的H5N1血凝素结构揭示了一个被自身糖基占据的受体结合位点。 |
Morano, N. C. |
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N/A |
Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan |
| 利用冷冻电镜直接从免疫血清中发现功能性和表位特异性的单克隆抗体 |
Ferguson, J. A. |
PDF |
N/A |
Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryoEM |
| 转录组学图谱及伤口床周围的免疫微环境定义了小鼠指尖截肢后的再生与非再生结果 |
Prabahar, A. |
PDF |
N/A |
Transcriptomic Landscape and Immune Microenvironment AroundWound Bed Define Regenerative versus Non-regenerative Outcomesin Mouse Digit Amputation |
| 揭示真食虫动物中微生物的多样性、传播途径及其人畜共患潜力 |
Li, H. |
PDF |
N/A |
Unveiling the diversity, transmission, and zoonotic potential of microbes in true insectivores |
| 在混合小鼠多样性面板中，盐性和可卡因自我给药的遗传差异 |
Khan, A. H. |
PDF |
N/A |
Differing genetics of saline and cocaine self administration in the hybrid mouse diversity panel |
| 利用3D生物打印的人类皮肤等效物识别强力HSV抗病毒药物 |
Ellison, S. T. |
PDF |
N/A |
Identification of potent HSV antivirals using 3D bioprinted human skin equivalents |
| 载有神经递质的DNA纳米笼作为基于α-突触核蛋白的神经病变细胞和体内潜在治疗剂 |
Vaswani, P. |
PDF |
N/A |
Neurotransmitter loaded DNA nanocages as potential therapeutics for α-synuclein based neuropathies in cells and in vivo |
| 磁力诱导磁小体链（MAGiC）：一种高性能且可导航的生物磁性粒子成像示踪剂 |
Li, L. |
PDF |
N/A |
Magnetically induced magnetosome chain (MAGiC):A biogenic magnetic-particle-imaging tracer with high performance and navigability |
| 酵母知识图谱数据库，用于探索酿酒酵母和裂殖酵母 |
Kumar, M. R. |
PDF |
N/A |
Yeast Knowledge Graphs Database for Exploring Saccharomyces cerevisiae and Schizosaccharomyces pombe |
| 超越细胞聚类和特征聚合：单细胞ATAC-seq数据中是否存在单细胞水平的信息？ |
Kwok, A. W. C. |
PDF |
N/A |
Going beyond cell clustering and feature aggregation: Is there single cell level information in single-cell ATAC-seq data? |
| MEGA-FISH：面向大规模空间组学的多组学可扩展GPU加速FISH处理框架 |
Ito, Y. |
PDF |
N/A |
MEGA-FISH: Multi-omics Extensible GPU-Accelerated FISH Processing Framework for Huge-Scale Spatial Omics |
| 四种皮肤类型中用于维生素D3合成的太阳紫外线B辐射 - 模型传播研究 |
Pasricha, P. K. |
PDF |
N/A |
Solar UVB Radiation for the Synthesis of Vitamin D3 in Four Skin Types - Model Propagation Studies |
| 新见解：槲皮素金属离子螯合物对红斑减少的作用 |
Bolano Alvarez, A. |
PDF |
N/A |
New insight into erythema reduction induced by quercetin metal ions chelates |
| HIV-1 Rev蛋白形成一个锌连接的二聚体。 |
Khan, R. S. |
PDF |
N/A |
HIV-1 Rev Protein Forms a Zinc-Linked Dimer |
| 在单细胞水平上识别疾病特异性易损状态 |
D'Antuono, M. |
PDF |
N/A |
Identification of disease-specific vulnerability states at the single-cell level |
| 一个针对真核生物线粒体细胞色素氧化酶亚基I基因（eKOI）的新型分类数据库：在宏条形码分析中提高群落水平的分类分辨率 |
Gonzalez-Miguens, R. |
PDF |
N/A |
A Novel Taxonomic Database for eukaryotic Mitochondrial Cytochrome Oxidase subunit I Gene (eKOI): Enhancing taxonomic resolution at community-level in metabarcoding analyses |
| 从灾难到侵袭：通过森林结构和气象分析，将风灾树木损害与树皮甲虫爆发联系起来 |
Torresani, M. |
PDF |
N/A |
From calamity to infestation: linking windstorm tree damage to bark beetle outbreak through forest structure and meteorological analysis |
| 跨越物种界限：环境DNA和基因分析揭示了美洲鳗鱼分布末端的杂交定居 |
Jacobsen, M. W. |
PDF |
N/A |
Bridging species boundaries: eDNA and genetic analysis reveal hybrid settlement at the very end of American eel distribution |
| 成年人类下丘脑中单细胞分辨率的空间解析分子性别差异 |
Mulvey, B. |
PDF |
N/A |
Spatially-resolved molecular sex differences at single cell resolution in the adult human hypothalamus |
| 通过整合静电纺膜和流动在肾小球共培养中生物制造过滤屏障 |
mussoni, c. |
PDF |
N/A |
Biofabrication of a filtration barrier by integrating electrospun membranes and flow in a glomerular co-culture |
| 用于血友病A基因治疗的工程化凝血因子VIII，具有增强的分泌和凝血潜力 |
Kashiwakura, Y. |
PDF |
N/A |
Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy |
| 将人口聚类与基因组流行病学整合于PopPIPE |
McHugh, M. P. |
PDF |
N/A |
Integrated population clustering and genomic epidemiology with PopPIPE |
| NCPepFold：通过多粒度表示的环化优化实现非规范环肽结构的准确预测 |
Mao, Q. |
PDF |
N/A |
NCPepFold: Accurate Prediction of Non-canonical Cyclic Peptide Structures via Cyclization Optimization with Multigranular Representation |
| CCR1抑制增强了多发性骨髓瘤细胞对糖皮质激素治疗的敏感性。 |
Luyckx, B. |
PDF |
N/A |
CCR1 inhibition sensitizes multiple myeloma cells toglucocorticoid therapy |
| 在癌症中追逐不存在的微小RNA |
Orang, A. |
PDF |
N/A |
Chasing non-existent microRNAs in cancer |
| 骨保护素与纤维调节蛋白-1的相互作用对于纤维化肺组织中细胞外基质的沉积至关重要。 |
Liu, Y. |
PDF |
N/A |
Interaction of osteoprotegerin with fibulin-1 is essential for extracellular matrix deposition in fibrotic lung tissue |
| ARID1A诱导的转录重编程重塑了黑色素瘤中对药物治疗的信号响应。 |
Barker, C. G. |
PDF |
N/A |
ARID1A-induced transcriptional reprogramming rewires signalling responses to drug treatment in melanoma |
| 自我信念形成的时间相关波动 |
Mayer, A. V. |
PDF |
N/A |
Time-of-day related fluctuations of self-belief formation |
| 动词-小品词结构的认知动态：一项眼动研究 |
Kissane, H. |
PDF |
N/A |
Cognitive Dynamics of Verb-Particle Constructions: An Eye-Tracking Study |
| 肌肉、前庭和触觉刺激对梦境整合影响的比较研究 |
Peters, E. |
PDF |
N/A |
A Comparative Study of Muscular, Vestibular, and Haptic Stimulation on Dream Incorporation |
| 小鼠海马CA1区锥体神经元的一个子集学习稀疏的突触输入模式。 |
Shahul, A. K. |
PDF |
N/A |
A subset of mouse hippocampus CA1 pyramidal neurons learns sparse synaptic input patterns. |
| 在有或没有视觉刺激的情况下，视觉皮层各区域间的逐次交互作用 |
Hidalgo, D. |
PDF |
N/A |
Trial-by-trial inter-areal interactions in visual cortex in the presence or absence of visual stimulation |
| 大脑反应的持续时间各不相同——建模策略与挑战 |
Skukies, R. S. |
PDF |
N/A |
Brain responses vary in duration - modelingstrategies and challenges |
| 访问TIL衍生的CD8 T细胞在可切除的HBV-HCC患者中抑制肿瘤复发的能力 |
Kah, J. |
PDF |
N/A |
Accessing the specific capacity of TIL-derived CD8 T-cells to suppress tumor recurrence in resectable HBV-HCC patients |
| Cited4a限制了斑马鱼心脏再生过程中心肌细胞的去分化和增殖 |
Forman-Rubinsky, R. |
PDF |
N/A |
Cited4a limits cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration |
| 扩散进化只能从气候变化中拯救有限数量的物种 |
Kamal, P. |
PDF |
N/A |
Dispersal evolution can only rescue a limited set of species from climate change |
| ActinoMation：一种用于中通量链霉菌属机器人接合的文学编程方法 |
Moeller, T. A. |
PDF |
N/A |
ActinoMation: a literate programming approach for medium-throughput robotic conjugation of Streptomyces spp. |
| 用于组成性高通量测序数据差异丰度检验的评分匹配方法 |
Ostner, J. |
PDF |
N/A |
Score matching for differential abundance testing of compositional high-throughput sequencing data |
| NicheTrans：空间感知的多组学翻译 |
Wang, Z. |
PDF |
N/A |
NicheTrans: Spatial-aware Cross-omics Translation |
| 通过活性噪声对细胞质粘度的超灵敏调控 |
Zhao, Z. |
PDF |
N/A |
Ultrasensitive tuning of cytoplasmic viscosity via active noise |
| 白细胞介素-4诱导CD11c+小胶质细胞，从而改善小鼠的神经性疼痛 |
Kohno, K. |
PDF |
N/A |
Interleukin-4 induces CD11c+ microglia leading to amelioration of neuropathic pain in mice |
| 高分辨率运动学方法用于量化肌营养不良斑马鱼幼体的运动障碍 |
Widrick, J. J. |
PDF |
N/A |
High resolution kinematic approach for quantifying impaired mobility of dystrophic zebrafish larvae |
| 水稻叶片超疏水性的结构、遗传和适应性基础 |
Hiraiwa, A. |
PDF |
N/A |
Structural, genetic, and adaptive basis of superhydrophobicity in rice leaves |
| 印度和坦桑尼亚大规模现场研究中的脑电数据质量 |
Vianney, S. J.-M. |
PDF |
N/A |
EEG data quality in large scale field studies in India and Tanzania |
| 在人类和非人类灵长类动物中发现了与疫苗介导的结核病保护相关的体液相关性 |
Kelkar, N. S. |
PDF |
N/A |
Humoral correlate of vaccine-mediated protection from tuberculosis identified in humans and non-human primates |
| 人类参考基因集中有超过2,500个编码基因的状态仍未确定。 |
Maquedano, M. |
PDF |
N/A |
More than 2,500 coding genes in the human reference gene set still have unsettled status |
| 视网膜节细胞类型中与胆碱能视网膜波破坏相关的转录组变化 |
Somaiya, R. D. |
PDF |
N/A |
Transcriptomic changes in retinal ganglion cell types associated with the disruption of cholinergic retinal waves |
| 为动态GABA编辑的磁共振波谱数据进行稳健的时间子采样建模：考虑射击间变异性 |
Craven, A. R. |
PDF |
N/A |
Modelling inter-shot variability for robust temporal sub-sampling of dynamic, GABA-edited MR spectroscopy data |
| 大型效应生命史基因组区域与大西洋鲑的功能形态特征相关 |
Aykanat, T. |
PDF |
N/A |
Large effect life-history genomic regions are associated with functional morphological traits in Atlantic salmon |
| 红藻UV性染色体的结构和进化特征 |
Lipinska, A. P. |
PDF |
N/A |
Structural and evolutionary features of red algal UV sex chromosomes |
| 微小RNA的协同缺失揭示了啮齿动物基因调控的多层次重构 |
Langschied, F. |
PDF |
N/A |
Concerted loss of micro-RNAs uncovers multi-level restructuring of gene regulation in rodents |
| 真菌毒素和草甘膦残留对欧洲黇鹿肠道微生物群及抗性组的影响 |
Toth, A. G. |
PDF |
N/A |
Impact of Mycotoxins and Glyphosate residue on the Gut Microbiome and Resistome of European Fallow Deer |
| 鸽子对注视的跟随行为随着示范者数量的增加而增加。 |
Delacoux, M. |
PDF |
N/A |
Gaze Following in Pigeons Increases with the Number of Demonstrators |
| BioMedGraphica：一个集成的平台，用于生物医学先验知识和组学信号图生成 |
Zhang, H. |
PDF |
N/A |
BioMedGraphica: An All-in-One Platform for Biomedical Prior Knowledge and Omic Signaling Graph Generation |
| Gfa2bin通过将基因组图转换为泛基因组基因型，实现了基于图的GWAS（全基因组关联分析）。 |
Vorbrugg, S. |
PDF |
N/A |
Gfa2bin enables graph-based GWAS by converting genome graphs to pan-genomic genotypes |
| 单分子生物剂量测定法 |
Lamontagne, M. |
PDF |
N/A |
Single-molecule biodosimetry |
| 一种利用多物种基因组模型和基于原生质体的宏量并行报告基因分析来调控植物基因表达的可扩展方法 |
Jevtic, S. |
PDF |
N/A |
A scalable method for modulating plant gene expression using a multispecies genomic model and protoplast-based massively parallel reporter assay |
| 单体/二聚体开关调节植物腺苷激酶的活性。 |
Kopecny, D. J. |
PDF |
N/A |
The monomer/dimer switch modulates the activity of plant adenosine kinase |
| 《一百个神经网络与大脑观看视频：从对齐中汲取的教训》 |
Sartzetaki, C. |
PDF |
N/A |
One Hundred Neural Networks and Brains Watching Videos: Lessons from Alignment |
| 使用滞后希尔伯特自相关法对神经节律性进行多尺度参数化 |
Zhang, S. |
PDF |
N/A |
Multi-scale parameterization of neural rhythmicity with lagged Hilbert autocoherence |
| 使用滞后希尔伯特自相关对神经节律性进行多尺度参数化 |
Zhang, S. |
PDF |
N/A |
Multi-scale parameterization of neural rhythmicity with lagged Hilbert autocoherence |
| deepBlastoid：一种基于深度学习的高通量分类器，用于使用明场图像对人类囊胚进行分类，并附带置信度评估 |
Fan, Z. |
PDF |
N/A |
deepBlastoid: A Deep Learning-Based High-Throughput Classifier for Human Blastoids Using Brightfield Images with Confidence Assessment |
| 单细胞数据的系统发育动力学推断 |
Dieselhorst, T. |
PDF |
N/A |
Phylodynamic inference on single-cell data |
| 酶调控的非热波动增强配体扩散和受体介导的内吞作用 |
Nividha, |
PDF |
N/A |
Enzyme-Regulated Non-Thermal Fluctuations Enhance Ligand Diffusion and Receptor-Mediated Endocytosis |
| 心肌细胞STIM1下调通过失调线粒体超微结构和代谢信号，加剧心肌梗死后重塑 |
Cacheux, M. |
PDF |
N/A |
Cardiomyocyte STIM1 downregulation exacerbates post-Myocardial Infarction remodeling by dysregulating mitochondrial ultrastructure and metabolic signaling |
| 鉴定非洲爪蟾胚胎组织中的类脑功能信息架构。 |
Varley, T. |
PDF |
N/A |
Identification of brain-like functional information architectures in embryonic tissue of Xenopus laevis. |
| 朊病毒疾病的二价siRNA |
Gentile, J. E. |
PDF |
N/A |
Divalent siRNA for prion disease |
| 使用交互式视觉语言系统对行走环境的自我中心感知 |
Tan, H. |
PDF |
N/A |
Egocentric perception of walking environments using an interactive vision-language system |
| 与tau蛋白过度磷酸化相关的老年猕猴内嗅皮层钙信号失调。 |
Bathla, S. |
PDF |
N/A |
Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation. |
| 古代沉积物中的DNA显示，在格兰德提顿国家公园，海狸连续居住了超过5000年。 |
Baker, D. N. |
PDF |
N/A |
Ancient sedimentary DNA shows more than 5000 years of continuous beaver occupancy in Grand Teton National Park |
| 萨马科尾矿坝灾难发生六年后植物的招募：对物种丰富度和植物生长的影响 |
Paz, A. A. |
PDF |
N/A |
Plant recruitment six years after the Samarcos tailings-dam disaster: Impacts on species richness and plant growth |
| 微粒局部递送生长因子调控体外鸡胚骨模型中依赖生长因子的成骨和成软骨基因表达。 |
Rashidi, H. |
PDF |
N/A |
Localized Delivery of Growth Factors from Microparticles Modulate Osteogenic and Chondrogenic Gene Expression in Growth Factor-dependent Manner in an ex vivo Chick Embryonic Bone Model. |
| 定义SARS-CoV-2刺突糖蛋白受体结合基序中高度保守的B细胞表位 |
Malladi, S. K. |
PDF |
N/A |
Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein |
| 罗氏菌属新种Rhodococcus parequi sp. nov.，是从马场土壤中分离得到的一种新种，与病原菌Rhodococcus equi密切相关。 |
Vazquez-Boland, J. A. |
PDF |
N/A |
Rhodococcus parequi sp. nov., a new species isolated from equine farm soil closely related to the pathogen Rhodococcus equi. |
| 人乳微生物组宏基因组检测方法的优化 |
Zhang, Q. |
PDF |
N/A |
Optimization of metagenomic detection method for human breast milk microbiome |
| 细菌的Site 2蛋白酶通过靶向噬菌体裂解蛋白，在抵抗RNA噬菌体中发挥作用。 |
Bae, H.-W. |
PDF |
N/A |
A bacterial site 2 protease contributes to RNA phage resistance by targeting phage lysis protein |
| 冷冻电镜解析了古菌双链DNA病毒HFTV1从头部到尾部的结构。 |
Zhang, D. X. |
PDF |
N/A |
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail |
| mRNA从核糖体中释放出来并配对作为单向正向旁路跳跃的驱动力的证据：其停止允许反向扫描。 |
Atkins, J. |
PDF |
N/A |
Evidence for the pairing of mRNA exiting ribosomes acting as a Driver of unidirectional forward bypassing: Its cessation permits Backwards scanning |
| 章鱼中的Z染色体剂量补偿与一种雄性特异性长链非编码RNA |
Papanicolaou, N. |
PDF |
N/A |
Z-chromosome dosage compensation and a male-specific lncRNA in octopus |
| 结构更多，精度更少：ESM3的结合预测悖论 |
Loux, T. |
PDF |
N/A |
More Structures, Less Accuracy: ESM3's Binding Prediction Paradox |
| XPG-DNA损伤结合动态的调控：由切刻前和切刻后核酸切除修复因子和EXO1共同参与 |
Muniesa-Vargas, A. |
PDF |
N/A |
Regulation of XPG-DNA damage binding dynamics by pre- and post-incision nucleotide excision repair factors and EXO1 |
| XRN1 提供游离核苷酸，以支持阿尔法病毒的复制过程。 |
Ruscica, V. |
PDF |
N/A |
XRN1 supplies free nucleotides to feed alphavirus replication |
| DDI-GPT：利用知识图谱增强的大型语言模型进行药物-药物相互作用的解释性预测 |
Xu, C. |
PDF |
N/A |
DDI-GPT: Explainable Prediction of Drug-Drug Interactions using Large Language Models enhanced with Knowledge Graphs |
| SARS-CoV-2刺突蛋白进化的综合分析：表位分类与免疫逃逸预测 |
Teruel, N. F. B. |
PDF |
N/A |
Comprehensive Analysis of SARS-CoV-2 Spike Evolution: Epitope Classification and Immune Escape Prediction |
| DNA复制介导的双组分调控系统激活作为Burkholderia thailandensis的一种对冲策略 |
Lowrey, L. C. |
PDF |
N/A |
DNA duplication-mediated activation of a two-component regulatory system serves as a bet-hedging strategy for Burkholderia thailandensis |
| 爱沙尼亚人群肠道古菌收集 |
Pantiukh, K. |
PDF |
N/A |
Human gut archaea collection from Estonian population |
| 群体感应调节的小RNA Lrs1参与了铜绿假单胞菌对低铁环境的适应。 |
Panagiotopoulou, D. |
PDF |
N/A |
The Quorum Sensing regulated sRNA Lrs1 is involved in the adaptation to low iron in Pseudomonas aeruginosa |
| PqsE作为铜绿假单胞菌特异性LuxR型受体调节器的演变：来自假单菌属和伯克霍尔德菌属的启示 |
Paczkowski, J. E. |
PDF |
N/A |
Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia |
| 无肠海生蠕虫硫酸盐还原共生体的基因组和蛋白质组特征 |
D'Angelo, G. |
PDF |
N/A |
Genomic and proteomic characterization of sulfate-reducing symbionts of gutless marine annelids |
| 噪声暴露前后大鼠尿液蛋白质组的变化 |
Yang, M. |
PDF |
N/A |
Changes in urinary proteome of rats before and after noise exposure |
| 转录组分析揭示了新品种豚鼠肌肉肥大的MSTN突变及机制 |
Carmen, S. |
PDF |
N/A |
Transcriptomic Analysis Reveals MSTN Mutations and Mechanisms of Muscle Hypertrophy in a New Guinea Pig Breed |
| 转录因子与NIPBL/MAU2形成三元复合物，以在增强子上定位cohesin。 |
Fettweis, G. |
PDF |
N/A |
Transcription factors form a ternary complex with NIPBL/MAU2 to localize cohesin at enhancers |
| 通过单细胞RNA测序在三刺鱼中识别的不同细胞类型的进化速率存在差异。 |
Rodgers, M. L. |
PDF |
N/A |
Rates of evolution differ between cell types identified by single-cell RNAseq in threespine stickleback |
| 非典型结构与功能：来自Additional Sex Combs-like蛋白的PHD结构域 |
Reddington, C. J. |
PDF |
N/A |
Unconventional structure and function of PHD domains from Additional Sex Combs-like proteins |
| CECR2溴结构域展现出对乙酰化组蛋白与非组蛋白配体不同的结合模式。 |
Phillips, M. |
PDF |
N/A |
The CECR2 bromodomain displays distinct binding modes to select for acetylated histone proteins versus non-histone ligands. |
| 基于动力学和结构的比较：沉默型鞭毛蛋白与刺激型鞭毛蛋白与TLR5的相互作用 |
Bell, M. E. W. |
PDF |
N/A |
Kinetic and structure-based comparisons of silent and stimulatory flagellin interactions with TLR5 |
| 黏蛋白在流感病毒抑制中的结构决定因素：唾液酸化糖类与分子大小的协同作用 |
Butnarasu, C. |
PDF |
N/A |
Structural Determinants of Mucins in Influenza Virus Inhibition: The Synergistic Role of Sialylated Glycans and Molecular Size |
| 通过单电子氧化实现手性选择性光酶催化C(sp3)-H功能化 |
Zhu, J. |
PDF |
N/A |
Enantioselective photoenzymatic C(sp3)-H functionalization via single-electron oxidation of carbanions |
| 工程酵母中提取的必需固醇可防止蜜蜂群体数量下降 |
Moore, E. V. |
PDF |
N/A |
Essential sterols from engineered yeast prevent honeybee colony population decline |
| 实证研究表明，转移性喂养能提高地面筑巢鸟类的生产力。 |
Bamber, J. A. |
PDF |
N/A |
Empirical evidence that diversionary feeding increases productivity in ground-nesting birds. |
| 在人工环境中通过调整环境条件实现造礁珊瑚的“非季节性”产卵 |
Koukoumaftsis, L. P. |
PDF |
N/A |
Controlled 'out-of-season' spawning of reef-forming corals in aquaria using offset environmental profiles |
| 极度濒危的阿拉伯剑羚（Gazella arabica acacia）饮食策略的保育意义 |
Lavie, N. |
PDF |
N/A |
Conservation implications of dietary strategies in the critically endangered Acacia gazelle (Gazella arabica acacia) |
| 基于凝集素的天然糖RNA的简单快速检测 |
Li, Y. |
PDF |
N/A |
Simple and rapid lectin-based detection of native glycoRNAs |
| 鸣禽在东喜马拉雅混种鸟群中处于更核心的地位。 |
Gupta, S. |
PDF |
N/A |
Vocal species are more central in Eastern Himalayan Mixed-Species bird flocks |
| 共生效应、产卵不同步以及混合繁殖模式在常见的大规模产卵珊瑚中 |
Ricardo, G. F. |
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N/A |
Allee effects, spawning asynchrony, and mixed reproductive modes in a common mass spawning coral |