| 一个bHLH相互作用代码控制果蝇肠道中的双向分化和自我更新 |
Puig-Barbe, A. |
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N/A |
A bHLH interaction code controls bipotential differentiation and self-renewal in the Drosophila gut |
| Balbiani小体是在卵母细胞发育早期，由微管调控的Buc分子凝聚形成的。 |
Kar, S. |
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N/A |
The Balbiani body is formed by microtubule-controlled molecular condensation of Buc in early oogenesis |
| E3泛素连接酶DTX3L和去泛素化酶USP28通过相互调节彼此的蛋白水平，精细调控DNA双链修复过程。 |
Mennerich, D. |
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N/A |
The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA double strand repair through mutual regulation of their protein levels |
| 整合多个单细胞多组学样本与Smmit |
Wan, C. |
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N/A |
Integrating multiple single-cell multi-omics samples with Smmit |
| 人类TUBA1B短开放阅读框产物通过importin-β调控癌细胞生长 |
Tao, Y. |
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N/A |
Human TUBA1B short open reading frame product regulates cancer cell growth via importin-β |
| 评估基础模型在单细胞数据分析中的效用 |
Liu, T. |
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N/A |
Evaluating the Utilities of Foundation Models in Single-cell Data Analysis |
| 数据驱动估计中对全脑单变量关联研究可重复性的偏差。 |
Burns, C. D. G. |
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N/A |
Bias in data-driven estimates of the reproducibility of univariate brain-wide association studies. |
| 髓系细胞驱动的内皮细胞向周细胞的转分化促进了中风后血脑屏障功能的恢复和大脑的自愈。 |
Li, T. |
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N/A |
The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke |
| 静息态7T fMRI中的跨皮层深度多层网络分析 |
Kotlarz, P. |
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N/A |
Multilayer Network Analysis across Cortical Depths in Resting-State 7T fMRI |
| 使用来自相同读数的核和叶绿体数据进行亚科进化分析 |
Witharana, E. P. |
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N/A |
Subfamily evolution analysis using nuclear and chloroplast data from the same reads |
| 语音特征处理中的神经动力学：证据表明特征从声学到句法处理的逐步进展 |
Karunathilake, I. M. D. |
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N/A |
Neural Dynamics of the Processing of Speech Features: Evidence for a Progression of Features from Acoustic to Sentential Processing |
| NAB2-STAT6驱动了孤立性纤维瘤中依赖EGR1的神经内分泌程序 |
Hill, C. |
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N/A |
NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in Solitary Fibrous Tumors |
| 在嵌入三维胶原蛋白基质的人类脂肪基质细胞中，肌腱分化程序被激活。 |
Horde, M. |
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N/A |
The tendon differentiation program is activated in human adipose stromal cells embedded in a 3D-collagen matrix |
| 表征相似性调节新奇的神经和行为特征 |
Becker, S. |
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N/A |
Representational similarity modulates neural and behavioral signatures of novelty |
| 通过基因丢失实现的大流行副溶血性弧菌波次更替 |
Yang, C. |
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N/A |
Pandemic Vibrio parahaemolyticus wave succession by gene loss |
| 地方选择塑造了欧洲玉米地方品种的多样性。 |
Takou, M. |
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N/A |
Local selection shaped the diversity of European maize landraces |
| 重新评估阅读障碍中的神经噪声假说：来自脑电图和7T磁共振波谱生物标志的见解 |
Glica, A. |
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N/A |
Reevaluating the Neural Noise Hypothesis in Dyslexia: Insights from EEG and 7T MRS Biomarkers |
| 噬菌体编码的Hm-oscar基因在茶小卷蛾（Homona magnanima）中再现了沃尔巴克氏体引发的雄性杀灭现象。 |
Arai, H. |
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N/A |
Prophage-encoded Hm-oscar gene recapitulates Wolbachia-induced male killing in the tea tortrix moth Homona magnanima |
| 时间细胞在学习过程的早期就会出现，并且编码超出任务要求的刺激模态。 |
Bhattacharjee, S. |
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N/A |
Time cells emerge early in learning and encode stimulus modality past task requirements |
| 运动序列学习引发与mu峰特异性相关的皮层脊髓可塑性 |
Suresh, T. |
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N/A |
Motor sequence learning elicits mu peak-specific corticospinal plasticity |
| Hopfield Kuramoto模型中的脑波动力学 |
Yao, R. |
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N/A |
Brain wave dynamics in Hopfield Kuramoto model |
| 基因组位点的功能图谱揭示增强子受其靶基因的限制。 |
Eder, M. |
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N/A |
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene. |
| 遗传抑制相互作用在不同遗传背景下高度保守。 |
Paltenghi, C. |
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N/A |
Genetic suppression interactions are highly conserved across genetic backgrounds |
| 基于表面的与基于体素的有限元头部模型：应变响应的比较分析 |
Zhou, Z. |
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N/A |
Surface-Based vs. Voxel-Based Finite Element Head Models: Comparative Analyses of Strain Responses |
| 在运动规划中，连续效应揭示了高效编码 |
Wang, T. |
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N/A |
Sequential Effects in Reaching Reveal Efficient Coding in Motor Planning |
| Orthrus：迈向进化与功能的RNA基础模型 |
Fradkin, P. |
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N/A |
Orthrus: Towards Evolutionary and Functional RNA Foundation Models |
| 单分子实验定位精度与理论定位精度之比取决于传感器，通常大于1。 |
Brenlla-Lopez, A. |
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N/A |
The ratio between experimental and theoretical localization precision of single molecules is sensor-dependent and typically larger than one |
| 生物系统适应的累积剂量反应 |
Gupta, A. |
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N/A |
Cumulative dose responses for adapting biological systems |
| 重复的香烟烟雾暴露会降低体外培养的人原代肺成纤维细胞的增殖率。 |
Cannard, E. C. |
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N/A |
Repeated cigarette smoke exposure attenuates the proliferation rate of primary human lung fibroblasts in vitro |
| 永生化的肠系膜间质细胞——体外干细胞龛 |
Canella, M. |
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N/A |
Immortalized Intestinal Telocytes - A Stem Cell Niche In Vitro |
| CAFE：一个集成式网络应用程序，用于光谱流式细胞术中的高维分析与可视化 |
Siam, M. H. B. |
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N/A |
CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry |
| PqsE作为铜绿假单胞菌特异性LuxR型受体调节因子的演变：来自假单胞菌和伯克霍尔德菌的见解 |
Mallery, C. P. |
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N/A |
Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia |
| 东非中晚期石器时代过渡的环境背景：季节性作为关键因素 |
Fusco, M. |
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N/A |
The environmental context of the Middle-to-Late Stone Age Transition in eastern Africa: seasonality as a key factor |
| 环境相关剂量的双酚A和S在子宫内暴露会跨代扰乱生殖细胞编程，通过单核多组学得以解决。 |
Zhao, L. |
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N/A |
Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omics |
| 中脑多巴胺神经元活动通过脑-体回路调节脾脏免疫 |
Gopinath, A. |
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N/A |
Brain-body circuit by which midbrain dopamine neuronal activity modulates splenic immunity |
| 饮食中单糖和双糖含量的耐受曲线决定了小鼠的体重增加、肠道微生物群组成和认知能力。 |
Bartochowski, P. |
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N/A |
Hormetic curve of dietary mono- and disaccharide content determines weight gain, gut microbiota composition and cognitive ability in mice |
| 使用功能性超声进行移动人脑成像 |
Soloukey, S. |
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N/A |
Mobile Human Brain Imaging using Functional Ultrasound |
| 甘氨酸与GABAA受体之间对gephyrin的竞争控制了它们在抑制性突触处的平衡群体 |
Kostrz, D. |
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N/A |
Competition between glycine and GABAA receptors for gephyrin controls their equilibrium populations at inhibitory synapses |
| 大麻素对机械敏感K+通道的抑制作用 |
Docter, T. |
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N/A |
Cannabinoid inhibition of mechanosensitive K+ channels |
| 一种新颖的薄荷醇-DCMU漂白方法用于有孔虫：为共生研究生成无共生体的宿主 |
Schmidt, C. |
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N/A |
A novel menthol-DCMU bleaching method for foraminifera: Generating aposymbiotic hosts for symbiosis research |
| SARS-CoV-2 Nsp4与宿主细胞ESCRT蛋白的协调作用诱导了内质网形态的变化。 |
Kifer, A. |
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N/A |
Orchestration of SARS-CoV-2 Nsp4 and host-cell ESCRT proteins induces morphological changes of the endoplasmic reticulum |
| ATG16L1的WD结构域调控脂质运输，以维持细胞膜的完整性，从而限制流感病毒感染。 |
Bone, B. |
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N/A |
ATG16L1 WD domain regulates lipid trafficking to maintain plasma membrane integrity to limit influenza virus infection |
| JAK2-STAT3通路的调控促进了人类诱导多能干细胞衍生的肌源性祖细胞的扩增和成熟 |
Caputo, L. |
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N/A |
Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSCs-derived myogenic progenitor cells |
| 回顾一下：在巴塔哥尼亚火山灰降落后，胡蜂属（Vespula spp.）的重新入侵情况。 |
Pereira, A. J. |
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N/A |
Circling back: Vespula spp. re-invasion after knockout from volcanic ash fall in Patagonia |
| 钴在河流生物膜中诱导新结构网络的形成：自养-异养耦合的损害。 |
Gourgues, S. |
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N/A |
Cobalt induces the set-up of new structural network in river biofilms: Impairment of autotrophic-heterotrophic coupling. |
| 好的火源：量化美国西部野火的有益生态作用（2010-2020年） |
Balch, J. K. |
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N/A |
Good fire: quantifying the beneficial ecosystem work of western U.S. wildfires (2010-2020) |
| 全寄生植物Hydnoraceae中不同的重复序列揭示了基因组进化的游乐场 |
Kim, W. |
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N/A |
Diverging repeatomes in holoparasitic Hydnoraceae uncover a playground of genome evolution |
| 通用单拷贝敲入系统在秀丽隐杆线虫中的应用：一种质粒即可靶向所有染色体 |
Dinneen, E. |
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N/A |
Universal Single Copy Knock-In System in Caenorhabditis elegans: One Plasmid to Target All Chromosomes |
| 欧洲河七鳃鳗（Lampetra fluviatilis）和溪七鳃鳗（Lampetra planeri）全基因组组装的比较 |
Torresen, O. K. |
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N/A |
Comparison of whole-genome assemblies of European river lamprey (Lampetra fluviatilis) and brook lamprey (Lampetra planeri) |
| PhenoEncoder：一种基因组数据压缩的判别嵌入方法 |
Tas, G. |
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N/A |
PhenoEncoder: A Discriminative Embedding Approach to Genomic Data Compression |
| 行为生物力学：切叶蚁的切割行为取决于叶片边缘的几何形状 |
Puffel, F. |
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N/A |
Behavioural biomechanics: leaf-cutter ant cutting behaviour depends on leaf edge geometry |
| 利用计算工具来理解雷公藤甲素与XPB的相互作用 |
Gorrie, D. |
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N/A |
Leveraging computational tools to understand the triptolide-XPB interaction |
| 膜焦磷酸酶运输H+的快速动力学：直接耦合机制的证据 |
Anashkin, V. A. |
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N/A |
Rapid kinetics of H+ transport by membrane pyrophosphatase: evidence for a direct-coupling mechanism |
| 一种可拉伸且仿生的聚氨酯膜，用于体外肺泡模型构建 |
Mitta, E. |
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N/A |
A stretchable and biomimetic polyurethane membrane for lung alveolar in vitro modelling |
| NucleoSeeker - 精确过滤RNA数据库以整理高质量数据集 |
Upadhyay, U. |
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N/A |
NucleoSeeker - Precision filtering of RNA databases to curate high-quality datasets |
| HIPSTR：TreeAnnotator X 中的最高独立后验子树重建 |
Baele, G. |
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N/A |
HIPSTR: highest independent posterior subtree reconstruction in TreeAnnotator X |
| 侵袭性乳腺癌的自组织是由主动和被动向错动力学的相互作用驱动的。 |
Gottheil, P. |
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N/A |
Self organisation of invasive breast cancer driven by the interplay of active and passive nematic dynamics |
| 肿瘤断裂负荷量化了与结构变异相关的基因组不稳定性，这种不稳定性在多种癌症中具有生物学和临床相关性。 |
Lakbir, S. |
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N/A |
Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers |
| 基质金属蛋白酶-2作为脂肪细胞葡萄糖利用的新型调节因子 |
Lempicki, M. D. |
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N/A |
Matrix Metalloproteinase-2 as a novel regulator of glucose utilization by adipocytes |
| CLE4肽激素调控马铃薯的从头再生芽。 |
Gancheva, M. |
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N/A |
CLE4 peptide hormone regulates de novo shoot regeneration in potato |
| 识别发芽抑制剂CIPC的基因靶点 |
Grand, T. M. |
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N/A |
Identification of Gene Targets for the Sprouting Inhibitor CIPC |
| 离开科学：38个经合组织国家中生物学家的流失 |
Kwiek, M. |
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N/A |
Leaving Science: Attrition of Biologists in 38 OECD Countries |
| 性别差异对疼痛强度感知在疼痛方案标准化中的影响 |
Wragan, M. |
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N/A |
The impact of sex differences on perceived pain intensity in pain protocol standardization |
| 多组学整合与人类背根神经节蛋白质组学揭示TNFα信号传导为相关的性别二态性通路 |
Barry, A. M. |
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N/A |
Multi-omic integration with human DRG proteomics highlights TNFα signalling as a relevant sexually dimorphic pathway |
| 光照线索对颜色恒常性的影响在同时识别光照和反射率变化中的作用 |
Virtanen, L. S. |
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N/A |
The effect of illumination cues on color constancy in simultaneous identification of illumination and reflectance changes |
| 通过使用协变量分析和单倍型块对主要组织相容性复合体关联进行深入分析，揭示了艾滋病精英控制分子病因学的新机制。 |
Rahmouni, M. |
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N/A |
Deep analysis of the Major Histocompatibility Complex associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS |
| 评估氨基酸相似性感知k-mer在表示TCR库以进行分类时的实用性 |
Kockelbergh, H. |
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N/A |
Evaluating the utility of amino acid similarity-aware kmers to represent TCR repertoires for classification |
| 城市蜥蜴中极高的铅耐受性 |
Blanchette, A. |
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N/A |
Extreme lead tolerance in an urban lizard |
| 生命史策略能在多大程度上为物种保护规划提供信息？ |
Stevenson, E. A. |
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N/A |
To what extent can life history strategies inform species conservation planning? |
| UniFORM：面向多重组织成像的通用免疫荧光标准化 |
Wang, K. |
PDF |
N/A |
UniFORM: Towards Universal Immunofluorescence Normalization for Multiplex Tissue Imaging |
| 影响组蛋白乙酰化的化学扰动调控结直肠癌的分化 |
Likasitwatanakul, P. |
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N/A |
Chemical perturbations impacting histone acetylation governcolorectal cancer differentiation |
| 大麻（Cannabis sativa L.）中新型白粉病抗性位点（PM2）的定位与特性研究 |
Seifi, S. |
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N/A |
Mapping and characterization of a novel powdery mildew resistance locus (PM2) in Cannabis sativa L. |
| 生长素和色氨酸在链藻（Penium margaritaceum）中引发了共同的反应。 |
Weijers, D. |
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N/A |
Auxin and tryptophan trigger common responses in the streptophyte alga Penium margaritaceum |
| 几丁质土壤改良通过增强模式触发的免疫来引发系统性植物抗病性。 |
Makechemu, M. |
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N/A |
Chitin soil amendment triggers systemic plant disease resistance through enhanced pattern-triggered immunity |
| 未加载和加载货物的液泡分选受体1的腔内结构域（VSR1-Nt）的两种晶体结构揭示了两个货物结合位点及其运输机制。 |
Borges, R. J. |
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N/A |
The two crystal structures of unloaded and cargo-loaded Vacuolar Sorting Receptor 1 lumenal domain (VSR1-Nt) reveal two cargo binding sites and a mechanism of transport. |
| 纳米比亚的仙女圈：土壤线虫的敌对领地 |
Treonis, A. |
PDF |
N/A |
Namibian fairy circles: Hostile territory for soil nematodes |
| 捕食者与猎物互动中的诚实信号：检验资源分配假说 |
Burdfield-Steel, E. |
PDF |
N/A |
Honest signalling in predator-prey interactions: testing the resource allocation hypothesis |
| 阿尔瓦雷斯龙类恐龙肉食性饮食的令人信服的证据 |
WANG, S. |
PDF |
N/A |
Convincing Evidence of Carnivorous Diet in Alvarezsaurian Dinosaur |
| 呼吸、咀嚼和吞咽过程中舌根形态变化的动态 |
Liu, Z.-J. |
PDF |
N/A |
The Dynamics of Shape Changes in the Tongue Base during Respiration, Chewing and Swallowing |
| 功能失调的振荡爆发模式是导致患有注意力缺陷多动障碍（ADHD）的青少年工作记忆缺陷的基础。 |
Kavanaugh, B. |
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N/A |
Dysfunctional oscillatory bursting patterns underlie working memory deficits in adolescents with ADHD |
| 小鼠同源皮层中多感官汇聚的空间组织 |
Patel, K. P. |
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N/A |
Spatial organization of multisensory convergence in mouse isocortex |
| 性别特异性单转录本水平的小鼠脑内加压素及其受体（AVPR1a）图谱 |
Gumerova, A. A. |
PDF |
N/A |
Gender-specific Single Transcript Level Atlas of Vasopressin and its Receptor (AVPR1a) in the Mouse Brain |
| 在不同亚型、区域和物种中寻找神经元放电率适应性的转录组相关性：一项Patch-seq分析 |
Meng, J. H. |
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N/A |
In Search of Transcriptomic Correlates of Neuronal Firing-Rate Adaptation across Subtypes, Regions and Species: A Patch-seq Analysis |
| 来自腹侧被盖区的GABA能神经元代表并调节力矢量。 |
Jiang, Q. |
PDF |
N/A |
GABAergic neurons from the ventral tegmental area represent and regulate force vectors |
| 干细胞因子对浦肯野细胞抑制的调控 |
Zaman, T. |
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N/A |
Modulation of Purkinje Cell Inhibition by Stem Cell Factor |
| 网格细胞预测动物未来的移动。 |
Csordas, D. E. |
PDF |
N/A |
Grid cells anticipate the animal's future movement |
| 跨多发性神经病的多组学人类腓肠神经特征分析 |
Heming, M. |
PDF |
N/A |
Multi-omic characterization of human sural nerves acrosspolyneuropathies |
| 针对脂质代谢的一类新型天然驱虫药物 |
Zahreddine, H. |
PDF |
N/A |
A new class of natural anthelmintics targeting lipid metabolism |
| 高分辨率转录组影响分析：AIRE致病性变异p.Arg257Ter、p.Cys311Tyr及多基因风险变异p.Arg471Cys的影响 |
Berger, A. H. |
PDF |
N/A |
High-Resolution Transcriptional Impact of AIRE: Effects of Pathogenic Variants p.Arg257Ter, p.Cys311Tyr, and Polygenic Risk Variant p.Arg471Cys |
| 当前的转录组数据库和通过免疫检查点阻断进行免疫治疗的生物标志物发现 |
Zhang, H. |
PDF |
N/A |
Current transcriptome database and biomarker discovery for immunotherapy by immune checkpoint blockade |
| 通过比较分析Bos基因组揭示印度牛的免疫遗传基础 |
Thambiraja, M. |
PDF |
N/A |
Genetic basis of immunity in Indian cattle as revealed by comparative analysis of Bos genome |
| 构建包容性领导力：生物科学视角 |
Armstrong, E. M. |
PDF |
N/A |
Building Inclusive Leadership: A Biosciences Approach |
| 多变量恢复力指标预测虫媒疾病暴发：西尼罗河病毒案例研究 |
Delecroix, C. |
PDF |
N/A |
Multivariate resilience indicators to anticipate vector-borne disease outbreaks: a West Nile virus case-study |
| 早期胚胎发育中的成像翻译 |
Bensidoun, P. |
PDF |
N/A |
Imaging Translation in Early Embryo Development |
| 全球干旱地区功能多样性的偏颇图景 |
Tordoni, E. |
PDF |
N/A |
A skewed picture of functional diversity in global drylands |
| 老化与脑血流动态的光谱特性 |
Park, K. Y. |
PDF |
N/A |
Aging and the Spectral Properties of Brain Hemodynamics |
| 加巴喷丁对人类背根神经节的影响：供体特异性电生理和转录组学特征 |
Demeter, J. B. |
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N/A |
Gabapentin's Effect on Human Dorsal Root Ganglia: Donor-Specific Electrophysiological and Transcriptomic Profiles |
| 部分人类脉络丛上皮细胞表现出线粒体偏心分布以及与色素生成相关的酶TYRP1的独特表达。 |
Groh, A. M. |
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A subset of human choroid plexus epithelial cells exhibit mitochondrial eccentricity and distinct expression of the pigmentation-associated enzyme TYRP1 |
| FastReseg：利用转录本位置信息优化基于图像的细胞分割结果，应用于空间转录组学 |
Wu, L. |
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N/A |
FastReseg: using transcript locations to refine image-based cell segmentation results in spatial transcriptomics |
| UltimateSynth：适用于多对比度AI的磁共振成像物理学 |
Adams, R. |
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N/A |
UltimateSynth: MRI Physics for Pan-Contrast AI |
| 揭示核蛋白质的远程异质性组织与N6-甲基腺苷足迹法 |
Yang, W. |
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N/A |
Revealing long-range heterogeneous organization of nucleoproteins with N6-methyladenine footprinting |
| 细胞铁代谢失调会使对化疗产生抗性的癌细胞更容易发生铁死亡。 |
Loftus, L. |
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N/A |
Dysregulation of cellular iron predisposes chemotherapy resistant cancer cells to ferroptosis |
| 去神经支配的交感神经-β3肾上腺素受体介导的脂肪组织脂解作用减弱可减轻小鼠酒精性肝损伤 |
Wickramasinghe, P. |
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N/A |
Ablation of sympathetic nerve-β3 adrenergic receptor-mediated adipose tissue lipolysis attenuates alcohol-induced liver injury in mice |
| 九重atg8突变体为拟南芥中ATG8同工型的功能特化提供了遗传学证据 |
Del Chiaro, A. |
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Nonuple atg8 mutant provides genetic evidence for functional specialization of ATG8 isoforms in Arabidopsis thaliana |
| Pol II的降解会独立于转录丧失而激活细胞死亡。 |
Harper, N. W. |
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Pol II degradation activates cell death independently from the loss of transcription |
| FedPyDESeq2：一种用于批量RNA-seq差异表达分析的联邦框架 |
Muzellec, B. |
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FedPyDESeq2: a federated framework for bulk RNA-seq differential expression analysis |
| 跨越平面空间转录组学到三维细胞图谱的维度鸿沟 |
Lin, S. |
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Bridging the Dimensional Gap from Planar Spatial Transcriptomics to 3D Cell Atlases |
| 一种新型双特异性抗体CVL006在癌症治疗中对PD-L1和VEGF的双重靶向作用优于AK112 |
Wang, C. |
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A Novel Bispecific Antibody CVL006 Superior to AK112 for Dual Targeting of PD-L1 and VEGF in Cancer Therapy |
| 大规模微血管网络中的血流模拟与不确定性量化：应用于脑皮层网络 |
Rasmussen, P. M. |
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N/A |
Blood flow simulation and uncertainty quantification in extensive microvascular networks: Application to brain cortical networks |
| 触觉刺激减少或促进听觉流的分离：心理物理学与建模 |
Darki, F. |
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Tactile stimulations reduce or promote the segregation of auditory streams: psychophysics and modelling |
| 从新的果蝇疾病模型中洞察齿状核-红核-苍白球-路易体萎缩症 |
Prifti, M. V. |
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N/A |
Insights into Dentatorubral-Pallidoluysian Atrophy from a new Drosophila model of disease |
| 脑机接口神经解码算法的比较分析 |
Shevchenko, O. |
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N/A |
Comparative analysis of neural decoding algorithms for brain-machine interfaces |
| 在1型糖尿病早期，传统和调节性T细胞亚群中幼稚和效应T细胞表型的失衡 |
Niederlova, V. |
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N/A |
An imbalance of naive and effector T-cell phenotypes in early type 1 diabetes across conventional and regulatory subsets |
| GM-CSF通过激活多种信号通路，在军团菌感染期间增强了人单核细胞中的促炎性细胞因子反应。 |
Vazquez Marrero, V. R. |
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N/A |
GM-CSF engages multiple signaling pathways to enhance pro-inflammatory cytokine responses in human monocytes during Legionella infection |
| 果蝇中的sev-GAL4驱动因子不在幼虫腹神经节的八对背内侧神经元及其他一些神经元中表达：一项修正 |
Kaushik, V. |
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N/A |
The sev-GAL4 driver in Drosophila melanogaster does not express in the eight pairs of dorso-medial and some other neurons in larval ventral ganglia: A correction |
| 在一种寿命较短的负鼠的生殖细胞中，突变率低但雄性偏向明显 |
Pena-Garcia, Y. |
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Low mutation rate but high male-bias in the germline of a short-lived opossum |
| 二倍体起源、适应多倍化以及异源四倍体拟南芥瑞典种（Arabidopsis suecica）中重新二倍化的开始 |
Burns, R. |
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Diploid origins, adaptation to polyploidy, and the beginning of rediploidization in allotetraploid Arabidopsis suecica |
| 一种用于癌症免疫治疗的新型通用嵌合抗原受体（CAR）-片段抗体结合剂（FAB）分裂系统 |
Arina, A. |
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A new universal chimeric-antigen receptor (CAR)- fragment antibody binder (FAB) split system for cancer immunotherapy |
| DRUGSYNC：使用基于GCN图卷积网络和预学习的药物诱导基因表达谱来预测协同药物组合 |
Zhao, L. |
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DRUGSYNC: Prediction of Synergistic Drug Combinations Using GCN Graph Convolutional Network based and Pre-learned Drug-induced Gene Expression Profiles |
| DiscoEPG：一个用于昆虫电穿透图（EPG）信号特征分析的Python包 |
Dinh, Q. D. |
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DiscoEPG: A Python package for characterization of insect electrical penetration graph (EPG) signals |
| 改进多重蛋白质组学研究的实验设计和数据标准化 |
Fang, H. |
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N/A |
Improving design and normalization of multiplex proteomics study |
| 基于其近原子分辨率结构，进行一种荧光共振能量转移（FRET）实验，以定量测定人类β-心脏肌球蛋白相互作用头模体的水平。 |
Goluguri, R. R. |
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N/A |
A FRET assay to quantitate levels of the human β-cardiac myosin interacting heads motif based on its near-atomic resolution structure |
| 纳米颗粒在三维肿瘤模型中的积累与渗透：尺寸、形状和表面电荷的影响 |
Cybulski, P. |
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N/A |
Nanoparticle Accumulation and Penetration in 3D Tumor Models: the Effect of Size, Shape, and Surface Charge |
| 实验设计与系统松散性对个性化过程的影响：从心血管角度探讨 |
Saxton, H. |
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THE IMPACT OF EXPERIMENTAL DESIGNS & SYSTEM SLOPPINESS ON THE PERSONALISATION PROCESS: A CARDIOVASCULAR PERSPECTIVE |
| 从基于生物学的初级视觉皮层学习脉冲神经网络模型中，稀疏编码、平衡和去相关性的出现 |
Ruslim, M. A. |
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N/A |
Emergence of Sparse Coding, Balance and Decorrelation from a Biologically-Grounded Spiking Neural Network Model of Learning in the Primary Visual Cortex |
| SARITA：一种用于生成SARS-CoV-2刺突蛋白S1亚基的大型语言模型 |
Rancati, S. |
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SARITA: A Large Language Model for Generating the S1 Subunit of the SARS-CoV-2 Spike Protein |
| SARS-CoV-2包膜PDZ结合基序作为一种毒力因子，破坏宿主的上皮细胞间连接。 |
Alvarez, F. |
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The SARS-CoV-2 envelope PDZ Binding Motif acts as a virulence factor disrupting host's epithelial cell-cell junctions |
| 在阿尔茨海默病小鼠模型中，SARS-CoV-2感染加速了淀粉样蛋白的沉积。 |
Parekh, P. A. |
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Accelerated amyloid deposition in SARS-CoV-2 infected mouse models of Alzheimer's disease |
| 卡塔尔手工艺和体力劳动者接种基于BNT162b2 mRNA的COVID-19加强疫苗后的纵向细胞和体液免疫反应。 |
Thomas, R. |
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N/A |
Longitudinal cellular and humoral immune responses following Covid-19 BNT162b2-mRNA-based booster vaccination of craft and manual workers in Qatar. |
| COVID-19患者中分枝杆菌的差异性控制与CD28+ CD8+ T细胞相关 |
Llibre, A. |
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Differential control of mycobacteria among COVID-19 patients is associated with CD28+ CD8+ T cells |
| 在大规模队列中的GWAS显著性阈值 |
Cheruiyot, E. |
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N/A |
GWAS significance thresholds in large cohorts |
| 投资开放科学：资助者的关键考虑因素 |
Cobb-Lewis, D. E. |
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N/A |
Investing in Open Science: Key Considerations for Funders |
| 在执行抓取任务时，主导手和非主导手在神经和行为表现上具有可比性。 |
Balasubramanian, E. |
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N/A |
Comparable neural and behavioural performance in dominant and non-dominant hands during grasping tasks |
| 对SARS-CoV-2 KP.3.1.1刺突蛋白进化的结构和功能洞察 |
Feng, Z. |
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N/A |
Structural and Functional Insights into the Evolution of SARS-CoV-2 KP.3.1.1 Spike Protein |
| 一个预测机车地面反作用力的简单分析模型 |
Opolz, M. D. |
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N/A |
A simple analytical model for predicting locomotive ground reaction forces |
| 线粒体与核DNA在基因表达调控中的相互作用 |
Giannoulis, X. |
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N/A |
Interplay between mitochondrial and nuclear DNA in gene expression regulation |
| 资源环境的变化驱动了黑腹果蝇（Drosophila melanogaster）的适应性分化。 |
Beltz, J. K. |
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Variation in Resource Environment Drives Adaptive Divergence in Drosophila melanogaster |
| 谱系相关的人类分化配对基因（DPGs）表现出调控特征和进化趋势 |
Duan, G. |
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Lineage-associated Human Divergently-Paired Genes (DPGs) Exhibit Regulatory Characteristics and Evolutionary Trends |
| 一种新型HLA II类抗原呈递预测算法揭示了KRAS G12C特异性的免疫原性CD4表位 |
Sprague, D. |
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A novel HLA Class II presentation prediction algorithm deciphers immunogenic CD4 epitopes specific to KRAS G12C |
| 可逆且可重复使用的分隔式微流控芯片，用于背根神经节神经元的共培养 |
Moreau, S. |
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N/A |
Reversible and reusable compartmentalized microfluidic chip for coculture of dorsal root ganglion neurons |
| SOX2诱导的IL-1α介导的免疫抑制推动了上皮异型增生向恶性转化的进程。 |
Taner, H. F. |
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N/A |
SOX2-induced IL-1alpha-mediated immune suppression drives epithelial dysplasia malignant transformation |
| 分类群：利用几何形态测量学和机器学习区分袋鼠后颅骨以应用于动物考古学 |
Mein, E. |
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N/A |
Sorting the mob: using geometric morphometrics and machine learning to differentiate kangaroo postcrania for zooarchaeological applications |
| 在小鼠中通过转基因增强红血球生成素（erythroferrone）的表达，可以改善腺嘌呤诱导的慢性肾病中的贫血症状。 |
Czaya, B. |
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N/A |
Transgenic augmentation of erythroferrone in mice ameliorates anemia in adenine-induced chronic kidney disease |
| 元素分区、元素定位及海枣树暴露于NaCl后的转录组响应 |
Pongrac, P. |
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N/A |
Element partitioning, element localisation and transcriptome responses of date palms exposed to NaCl |
| 人类脉络丛微血管灌注和液体隔室的选择性放松扩散加权成像 |
Li, C. |
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N/A |
Relaxation selective Intravoxel Incoherent Motion Imaging of Microvascular Perfusion and Fluid Compartments in the Human Choroid Plexus |
| Collablots：量化胶原蛋白VI水平及其在胶原蛋白VI相关性肌营养不良症患者细胞培养中的结构紊乱情况 |
Osegui-Barcenilla, N. |
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N/A |
Collablots: Quantification of collagen VI levels and its structural disorganisation in cell cultures from patients with collagen VI-related dystrophies |
| 供体HLA DQ反应性B细胞在慢性免疫抑制下克隆性扩增，并包括具有高亲和力胚系B细胞受体的非典型CD21低CD27- B细胞。 |
Russum, S. |
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N/A |
Donor HLA DQ reactive B cells clonally expand under chronic immunosuppression and include atypical CD21lowCD27- B cells with high avidity germline B cell receptors. |
| 2009年至2020年间从人类流感A病毒株中分离出的N1神经氨酸酶的抗原图谱 |
Portela Catani, J. P. |
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N/A |
The antigenic landscape of N1 neuraminidase in human influenza A virus strains isolated between 2009 and 2020 |
| 对多细胞排列的整体分析将胚胎组织的多样性简化为两种原型，这两种原型需要特定的钙粘蛋白表达。 |
Brambach, M. |
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N/A |
In toto analysis of multicellular arrangement reduces embryonic tissue diversity to two archetypes that require specific cadherin expression |
| 热带森林土壤微生物群在升温条件下比在常温条件下对叶片耐热性的调节作用更强。 |
Hernandes Villani, G. |
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N/A |
Tropical Forest Soil Microbiome Modulates Leaf Heat Tolerance More Strongly Under Warming than Ambient Conditions |
| 通过深度代理模型实现可扩展的DNA特征生成与转录因子结合预测 |
Kabir, A. |
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N/A |
Scalable DNA Feature Generation and Transcription Factor Binding Prediction via Deep Surrogate Models |
| Scouter：利用大型语言模型嵌入预测基因扰动后的转录反应 |
Zhu, O. |
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N/A |
Scouter: Predicting Transcriptional Responses to Genetic Perturbations with LLM embeddings |
| 针对A类G蛋白偶联受体的安全药物大规模筛选的微调深度迁移学习模型 |
Provasi, D. |
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N/A |
Fine-Tuned Deep Transfer Learning Models for Large Screenings of Safer Drugs Targeting Class A G Protein-Coupled Receptors |
| 演示磁带：靶向单细胞测序数据的计算解复用 |
Borgsmueller, N. |
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N/A |
DemoTape: Computational demultiplexing of targeted single-cell sequencing data |
| 使用MPI并行化基于粒子的反应扩散模拟 |
Guo, S. |
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N/A |
Parallelization of particle-based reaction-diffusion simulations using MPI |