| 疫苗增强的竞争允许肠道内细菌菌株的合理替换 |
Lentsch, V. |
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N/A |
Vaccine-enhanced competition permits rational bacterial strain replacement in the gut |
| 在NMDA受体抗体脑炎小鼠模型中，胼胝体连接的中断是导致长期感觉运动障碍的基础。 |
Zhou, J. |
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N/A |
Disrupted callosal connectivity underlies long-lasting sensory-motor deficits in an NMDA receptor antibody encephalitis mouse model |
| 对真菌蚊基因组（双翅目：粪生迟眼蕈蚊）进行染色体水平支架搭建 |
Urban, J. M. |
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N/A |
Chromosome-scale scaffolding of the fungus gnat genome (Diptera: Bradysia coprophila) |
| 经验改变了控制突触可塑性和学习的时机规则 |
Jayabal, S. |
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N/A |
Experience Alters the Timing Rules Governing Synaptic Plasticity and Learning |
| 出口蛋白1/XPO1核输出途径抑制对冠状病毒复制的影响。 |
Rahman, M. M. |
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N/A |
Effect of exportin 1/XPO1 nuclear export pathway inhibition on coronavirus replication. |
| II类和III类病毒融合蛋白能够识别并重组复杂的生物膜结构。 |
Poojari, C. S. |
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N/A |
Viral fusion proteins of class II and III recognize and reorganize complex biological membranes |
| 一种新的管道SPICE识别出新的JUN-IKZF1复合元件 |
Li, P. |
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N/A |
A new pipeline SPICE identifies novel JUN-IKZF1 composite elements |
| 改善焦虑研究：通过多状态摘要指标揭示特质焦虑的新方法 |
Varga, Z. K. |
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N/A |
Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states |
| 单核细胞利用突出力在基于胶原蛋白的粘弹性细胞外基质中生成迁移路径。 |
Adebowale, K. |
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N/A |
Monocytes use protrusive forces to generate migration paths in viscoelastic collagen-based extracellular matrices |
| 乳腺癌细胞在脑转移阶段对肿瘤微环境的差异性适应与重塑 |
Wu, X. |
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N/A |
Differential Adaptation and Remodeling of the Tumor Microenvironment in Breast Cancer Cells During the Stages of Brain Metastasis |
| 光谱分解揭示了海鞘形态发生的过程 |
Dokmegang, J. |
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N/A |
Spectral decomposition unlocks ascidian morphogenesis |
| 在主动推理框架下人类决策中新颖性和变异性神经相关性 |
Zhang, S. |
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N/A |
The Neural Correlates of Novelty and Variability in Human Decision-Making under an Active Inference Framework |
| 癌症免疫疗法的效果在淋巴结切除后仍然持续。 |
Zhou, H. |
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N/A |
Cancer immunotherapy response persists after lymph node resection |
| 病毒基因组特征可预测正痘病毒的宿主 |
Tseng, K. K. |
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N/A |
Viral genomic features predict orthopoxvirus reservoir hosts |
| 早发性家族性阿尔茨海默病和Sanfilippo综合征斑马鱼模型的多组学分析揭示了疾病机制的共性 |
Barthelson, K. |
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N/A |
Multi-omics analyses of early-onset familial Alzheimer's disease and Sanfilippo syndrome zebrafish models reveal commonalities in disease mechanisms |
| 关于金鱼卵和胚胎的独立刺激性——关于金鱼卵中节律性卵黄收缩的活体交流 |
Sanchez, P. G. L. |
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N/A |
On the independent irritability of goldfish eggs and embryos -- a living communication on the rhythmic yolk contractions in goldfish |
| 越冬而非繁殖的海洋环境可能调节长途迁徙海鸟的存活率下降。 |
Snell, K. |
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N/A |
Wintering, rather than breeding, oceanic conditions may modulate declining survival in a long-distance migratory seabird |
| vmrseq: 单细胞甲基化异质性的概率建模 |
Shen, N. |
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N/A |
vmrseq: Probabilistic Modeling of Single-cell Methylation Heterogeneity |
| 揭示丘脑深部脑刺激背后的网络机制 |
Tian, Y. |
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N/A |
Uncovering network mechanism underlying thalamic deep brain stimulation |
| 元代谢组生态学揭示了地球化学和微生物功能潜力与七条河流中有机质发展之间的联系。 |
Danczak, R. E. |
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N/A |
Meta-metabolome ecology reveals that geochemistry and microbial functional potential are linked to organic matter development across seven rivers |
| 自然主义对话中，社会和语义背景对语音编码的影响 |
Abassi, E. |
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N/A |
Influence of social and semantic contexts on phonetic encoding in naturalistic conversations |
| 癌症相关成纤维细胞如何促进人类肺癌中T细胞的排除：一个物理学的视角 |
Ackermann, J. |
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N/A |
How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective |
| 估计神经网络中的有效连接性：基于导数和基于相关性方法的比较 |
Laasch, N. |
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N/A |
Estimating effective connectivity in neural networks: comparison of derivative-based and correlation-based methods |
| 生物相容性钕掺杂纳米晶体作为衍射极限体外温度传感探针 |
Bravo, M. |
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N/A |
Biocompatible Neodymium-Doped Nanocrystals as Probes for Diffraction-limited, in vitro Temperature Sensing |
| 限时进食导致小鼠消化系统的性别和器官特异性反应 |
Oparija-Rogenmozere, L. |
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N/A |
Time-restricted feeding leads to sex- and organ-specific responses in the murine digestive system |
| HippoMaps：人类海马结构的多尺度地图绘制 |
DeKraker, J. |
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N/A |
HippoMaps: Multiscale cartography of the human hippocampal formation |
| 在单个网格模块内，网格细胞属性的稳健变异性增强了局部空间的编码能力 |
Redman, W. T. |
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N/A |
Robust variability of grid cell properties within individual grid modules enhances encoding of local space |
| 在癌症FFPE样本中，RNA聚合酶II在组蛋白基因上的超转录 |
Henikoff, S. |
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N/A |
RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples |
| 55900种RNA病毒的元转录组综合分析揭示了RNA病毒组在全球污水处理厂中对人类健康的潜在影响及其生态角色 |
Yuan, L. |
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N/A |
Metatranscriptomic Compendium of 55900 RNA Viruses Deciphers Human Health Implication and Ecological roles of RNA Virome in Global Wastewater Treatment Plants |
| 道路密度简化了区域食物网。 |
Mestre, F. |
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N/A |
Road density simplifies regional food webs |
| KaiC的初始磷酸化是由其自激酶自我抑制的释放所激活的。 |
Furuike, Y. |
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N/A |
The priming phosphorylation of KaiC is activated by the release of its autokinase autoinhibition |
| 额叶外区域在有意识运动行为中的作用：一项使用快速光学成像的注册报告 |
Colombari, E. |
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N/A |
The role of extra-striate areas in conscious motor behavior: a registered report with Fast-Optical Imaging |
| HCF101是人类病原体刚地弓形虫（Toxoplasma gondii）中CIA胞质铁硫合成途径的新组分。 |
Renaud, E. A. |
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N/A |
HCF101 is a novel component of the CIA cytosolic iron-sulfur synthesis pathway in the human pathogen Toxoplasma gondii |
| 目标导向行为背后的视觉运动转换 |
Zhao, P. |
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N/A |
The visuomotor transformations underlying target-directed behavior |
| 一个在时间生物学上保守的复合体与秀丽隐杆线虫的发育时间相关。 |
Spangler, R. K. |
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N/A |
A conserved chronobiological complex times C. elegans development |
| 一种新的期望最大化方法，用于从时间序列遗传数据中推断一般二倍体选择 |
Fine, A. G. |
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N/A |
A novel expectation-maximization approach to infer general diploid selection from time-series genetic data |
| 在不同的神经决策信号中，对演化信念和瞬时信念更新的可分离编码 |
Pares-Pujolras, E. |
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N/A |
Dissociable encoding of evolving beliefs and momentary belief updates in distinct neural decision signals |
| 太平洋雨林中指示性莺类物种复合体的动态气候适应 |
Wang, S. |
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N/A |
The dynamic climate adaptation of indicator warbler species complex in the Pacific Rainforest |
| 骆驼科单域抗体对锥虫乳酸激酶的变构抑制 |
Pinto Torres, J. E. |
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N/A |
Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody |
| 植物圈中的挥发性有机化合物专家 |
Padaki, V. G. |
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N/A |
Volatile Organic Compound Specialists in the Phycosphere |
| 人类下丘中的快速和刺激特异性偏差检测 |
Wetekam, J. |
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N/A |
Rapid and Stimulus-Specific Deviance Detection in the Human Inferior Colliculus |
| 特发性震颤在自然运动过程中破坏了大脑的节律网络 |
West, T. |
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N/A |
Essential Tremor Disrupts Rhythmic Brain Networks During Naturalistic Movement |
| 一种由亲和力驱动的Twisted gastrulation调控细胞外BMP的机制 |
Moore, G. |
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N/A |
An avidity-driven mechanism of extracellular BMP regulation by Twisted gastrulation |
| 钠负荷正常血压小鼠血管重塑的性别相关差异 |
Silva, J. C. d. S. |
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N/A |
Sex-related differences in vascular remodeling of sodium overloaded normotensive mice |
| 局部核质比通过细胞周期状态调节H3.3的整合，在合子基因组激活期间发挥作用。 |
Bhatt, A. D. |
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N/A |
Local nuclear to cytoplasmic ratio regulates H3.3 incorporation via cell cycle state during zygotic genome activation |
| 发育中的鸡三叉神经节转录组图谱 |
Leonard, C. E. |
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N/A |
The transcriptional landscape of the developing chick trigeminal ganglion |
| 在南非的两个污水处理厂中检测到的隐孢子虫卵囊和贾第虫包囊 |
Gonose, T. |
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N/A |
Cryptosporidium oocysts and Giardia cysts at two South African wastewater treatment plants |
| 在条件学习过程中，延迟结果的信用分配的神经机制 |
Witkowski, P. |
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N/A |
Neural mechanisms of credit assignment for delayed outcomes during contingent learning |
| 血管紧张素转换酶中心模型：与计算的AT1受体和醛固酮水平相关的肽通量 |
Westwood, B. M. |
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N/A |
Angiotensin Converting Enzyme Hub Model of Peptide Flux Relating Calculated AT1 Receptor and Aldosterone Levels |
| 小鼠颅神经板空间和时间基因表达的单细胞图谱 |
Brooks, E. R. |
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N/A |
A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate |
| 功能性状和土壤水分可利用性塑造了二倍体-多倍体复合体中的竞争相互作用 |
Rodriguez-Parra, A. |
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N/A |
Functional traits and soil water availability shape competitive interactions in a diploid-polyploid complex |
| 大型齿鲸种内体长变化的总结 |
McClure, J. |
PDF |
N/A |
A summary of intraspecific size variation for large odontocetes |
| 一种统一的贝叶斯方法用于转录组关联研究 |
Khan, A. K. |
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N/A |
A unified Bayesian approach to transcriptome-wide association study |
| 鼻内给予锂盐可抑制大脑中的炎症性细胞焦亡，并改善5XFAD小鼠的记忆丧失和抑郁样行为。 |
Bhuiyan, P. |
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N/A |
Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD mice |
| 学习发育动力学的几何模型 |
Howe, A. E. S. |
PDF |
N/A |
Learning geometric models for developmental dynamics |
| 穴样蛋白-1调控尤文肉瘤中的环境依赖性信号传导与生存。 |
Segal, D. |
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N/A |
Caveolin-1 regulates context-dependent signaling and survival in Ewing Sarcoma. |
| 通过味觉受体检测细菌可启动细胞免疫反应 |
Mazariegos, A. N. |
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N/A |
Detection of bacteria through taste receptors primes the cellular immune response |
| Meta2DB：用于健康状态预测的精选鸟枪法宏基因组特征集和元数据 |
Kok, C. R. |
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N/A |
Meta2DB: Curated Shotgun Metagenomic Feature Sets and Metadata for Health State Prediction |
| 在灵长类腹侧前运动皮层中时间感知期间的情境神经动力学 |
Diaz, H. |
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N/A |
Contextual Neural Dynamics During Time Perception in Primate Ventral Premotor Cortex |
| 单突触腹侧被盖区谷氨酸投射至蓝斑，增强厌恶情绪处理。 |
Parker, K. E. |
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N/A |
Monosynaptic ventral tegmental area glutamate projections to the locus coeruleus enhance aversive processing |
| 个体在政策精确性上的差异：与自杀意念及默认模式网络动态的关联 |
Yoon, D. |
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N/A |
Individual Differences in Policy Precision: Links to Suicidal Ideation and Default Mode Network Dynamics |
| 关系整合需求是通过高阶皮层网络中阿尔法和贝塔节律的时延神经表征来追踪的。 |
Robinson, C. N. |
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N/A |
Relational integration demands are tracked by temporally delayed neural representations in alpha and beta rhythms within higher-order cortical networks |
| 用于分析力激活蛋白延伸和相互作用的DNA纳米装置 |
Zhou, K. |
PDF |
N/A |
DNA nanodevice for analysis of force-activated protein extension and interactions |
| 小分子脂筏稳定性调节剂和蛋白质-筏分配调节剂 |
Stefanski, K. M. |
PDF |
N/A |
Small-molecule modulators of lipid raft stability and protein-raft partitioning |
| 氧化应激对腺苷A2a受体结构、功能及信号传导的影响 |
Company, I. |
PDF |
N/A |
The effect of oxidative stress on the Adenosine A2a Receptor structure, activity and signalling |
| 细菌核糖体中药物结合残基的演变 |
Ekemezie, C. L. |
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N/A |
Evolution of drug-binding residues in bacterial ribosomes |
| 肌肉基生物混合设备的低成本打印机使用的3D打印树脂的细胞毒性和特性研究 |
Liao, A. S. |
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N/A |
Cytotoxicity and Characterization of 3D-Printable Resins Using a Low-Cost Printer for Muscle-based Biohybrid Devices |
| 细节决定成败！多模态个性化能够提升经颅直流电刺激对感觉运动整合调节的疗效。 |
Radecke, J.-O. |
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N/A |
Details matter! Multimodal personalization increases the efficacy of transcranial direct current stimulation for modulation of sensorimotor integration |
| 机器学习揭示了胶质母细胞瘤和骨肉瘤的新型治疗靶点 |
Li, N. |
PDF |
N/A |
Machine learning reveals novel targets for both glioblastoma and osteosarcoma |
| 超声组织碎裂术与人类多能干细胞衍生的肝球植入术作为先天性代谢性肝病潜在治疗手段的安全性与有效性：在免疫健全的啮齿动物模型中的评估。 |
Rashidi, H. |
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N/A |
The safety and efficacy of Ultrasound Histotripsy and human pluripotent stem cell-derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: assessment in an immunocompetent rodent model. |
| 连续的感觉运动转换增强了猕猴运动皮层神经动力学对扰动的鲁棒性 |
Zheng, C. |
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N/A |
Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex |
| 基于机制的方法在设计针对无义突变疾病的个性化联合疗法中的应用 |
Bhat, S. |
PDF |
N/A |
Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases |
| 蛋白质语言可视化工具：语言模型时代的序列相似性网络 |
Espinoza Herrera, J. |
PDF |
N/A |
The Protein Language Visualizer: Sequence Similarity Networks for the Era of Language Models |
| CellBinDB：一个大规模多模态注释细胞分割数据集，并附有通用模型的基准测试 |
Shi, C. |
PDF |
N/A |
CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models |
| 关键期信号通过线粒体活性氧（ROS）和缺氧诱导因子-1α（HIF-1α）指导神经系统发育。 |
Sobrid-Camean, D. |
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N/A |
Critical period signalling directs nervous system development through mitochondrial ROS and HIF-1α |
| 真核生物核糖体中药物结合残基的演变 |
Chan, L. I. |
PDF |
N/A |
Evolution of drug-binding residues in eukaryotic ribosomes |
| 热诱导的磷脂酰丝氨酸变化驱动HSPA1A在质膜的定位 |
Low, J. |
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N/A |
Heat-Induced Phosphatidylserine Changes Drive HSPA1A's Plasma Membrane Localization |
| 跨越上皮-间质转化（EMT）景观的过渡路径由网络逻辑决定。 |
Dey, A. |
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N/A |
Transition paths across the EMT landscape are dictated by network logic |
| 对已识别的果蝇神经元的突触进行分析，揭示了突触前活性区的细胞类型特异性空间排列。 |
Wu, H. |
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N/A |
Synapse profiling of identified Drosophila neurons revealed cell-type-specific spatial configurations of presynaptic active zones |
| 比较基因组学研究显示，立克次氏菌属细菌具有多种代谢特征，这些特征与其与节肢动物的共生相互作用有关。 |
Floriano, A. M. M. |
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N/A |
Comparative genomics of Rickettsiella bacteria reveal variable metabolic traits involved in symbiotic interactions with arthropods |
| 超分辨率成像揭示了CD81微区在调节Jurkat T细胞微绒毛膜信号传导中的空间组织 |
Ramseier, N. |
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N/A |
Superresolution Imaging Reveals the Spatial Organization of CD81 Microdomains in Regulating Membrane Signaling on Jurkat T Cell Microvilli |
| 基于先天适应性的早期运动训练的共享与独特适应 |
Sadler, D. G. |
PDF |
N/A |
Shared and distinct adaptations to early-life exercise training based on inborn fitness |
| 饮食中一糖和二糖含量的耐受曲线决定了小鼠的体重增加、肠道微生物群组成和认知能力。 |
Bartochowski, P. |
PDF |
N/A |
Hormetic curve of dietary mono- and disaccharide content determines weight gain, gut microbiota composition and cognitive ability in mice |
| AIRE的高分辨率转录组影响：致病变体p.Arg257Ter、p.Cys311Tyr和多基因风险变体p.Arg471Cys的影响 |
Berger, A. H. |
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N/A |
High-Resolution Transcriptional Impact of AIRE: Effects of Pathogenic Variants p.Arg257Ter, p.Cys311Tyr, and Polygenic Risk Variant p.Arg471Cys |
| 在埃希氏大肠杆菌中设计合成途径以生产(+)-短杆菌肽A和B |
Sandoval Hurtado, C. P. |
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N/A |
Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in Escherichia coli |
| 利用合成血清标志物在体内监测转录 |
Watanabe, S. |
PDF |
N/A |
Monitoring in vivo transcription with synthetic serum markers |
| 铁饥饿促使绿藻中的第二个LHCⅠ四聚体结合到光系统Ⅰ上。 |
Liu, H. W. |
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N/A |
Fe starvation induces a second LHCI tetramer to photosystem I in green algae |
| 不同家族间的传感器和辅助NLRs的共转移扩展了被子植物间的免疫受体功能 |
Du, X. |
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N/A |
Interfamily co-transfer of sensor and helper NLRs extends immune receptor functionality between angiosperms |
| 冷胁迫通过CBF依赖的调控途径重塑了桉树杂交种的木材形成。 |
Bachir, I. H. |
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N/A |
Cold stress involves CBF dependent regulatory pathway to remodel wood formation in Eucalyptus gunnii hybrids. |
| 简和迷你简，一个用于马铃薯功能基因组学的模型系统 |
Xin, H. |
PDF |
N/A |
Jan and mini-Jan, a model system for potato functional genomics |
| 胞质中的果糖——蔗糖生物合成调控中被低估的角色？ |
Giesbrecht, O. |
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N/A |
Cytosolic fructose - an underestimated player in the regulation of the sucrose biosynthesis? |
| 细胞增殖与细胞分裂方向的协调控制了拟南芥的径向花柱发育。 |
Jamil, I. |
PDF |
N/A |
The coordination of cell proliferation and cell-division orientation controls Arabidopsis radial style development |
| Lr14a介导的细胞质钙内流调控小麦对叶锈病的气孔免疫 |
Yue, L. |
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N/A |
Cytoplasmic calcium influx mediated by Lr14a regulates stomatal immunity against leaf rust in wheat |
| FaDAM3和FaDAM4是调控栽培草莓季节二态性的候选基因。 |
David, S. |
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N/A |
FaDAM3 and FaDAM4 are candidate genes for the regulation of seasonal dimorphism in cultivated strawberry |
| 双重红色过量（TREx）：一种简单而新颖的数字颜色指数，能够对绿叶以及富含花青素的作物进行无创实时健康评估。 |
Agarwal, A. |
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N/A |
Two-fold Red Excess (TREx): A simple and novel digital color index that enables non-invasive real-time health assessment of green-leaved as well as anthocyanin-rich crops |
| 烟草TA29和芝麻GN13启动子均能在转基因芝麻（Sesamum indicum L.）中提供花药特异性的GUS表达。 |
Debnath, A. J. |
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N/A |
Both tobacco TA29 and sesame GN13 promoters provide anther-specific GUS expression in transgenic sesame (Sesamum indicum L.) |
| 叶用莴苣中，细胞分裂素有效促进芽再生的浓度与种皮颜色之间的关系 |
Kimura, M. |
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N/A |
Relationship between concentration of cytokinin for efficient shoot regeneration and seed coat color in leaf lettuce |
| 恶性疟原虫（在马来西亚消灭前的临床分离株）的内在繁殖率变异 |
Stewart, L. B. |
PDF |
N/A |
Intrinsic multiplication rate variation of Plasmodium falciparum (in clinical isolates prior to elimination in Malaysia |
| 在马来西亚消除之前，临床分离的恶性疟原虫的内在繁殖率变化 |
Stewart, L. B. |
PDF |
N/A |
Intrinsic multiplication rate variation of Plasmodium falciparum in clinical isolates prior to elimination in Malaysia |
| 与环境敏感性和炎症相关生物标志物关系相关的肠道微生物组关键分类群 |
Takasugi, S. |
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N/A |
Key taxa of the gut microbiome associated with the relationship between environmental sensitivity and inflammation-related biomarkers |
| 利用环境DNA（eDNA）针对陆地脊椎动物的研究：趋势、展望及采样考虑 |
Newton, J. P. |
PDF |
N/A |
Targeting terrestrial vertebrates with eDNA: Trends, perspectives, and considerations for sampling |
| PlateletBase：一个综合性的血小板研究与疾病洞察知识库 |
Luo, H. |
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N/A |
PlateletBase: A Comprehensive Knowledgebase for Platelet Research and Disease Insights |
| 将生物分割数据集合理地进行FAIR存储 |
Ho, E. M. L. |
PDF |
N/A |
Depositing biological segmentation datasets FAIRly |
| FSTL3是一种预后不良的生物标志物，并与卵巢癌中的免疫治疗抵抗相关。 |
Chauvin, M. |
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N/A |
FSTL3 is a biomarker of poor prognosis and is associated with immunotherapy resistance in ovarian cancer. |
| 近红外实时无损监测糖分积累的研究表明，单个浆果的成熟速度比在标准异步样本上先前记录的要快两倍。 |
Tavernier, F. |
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N/A |
Near-infrared real time non-destructive monitoring of sugar accumulation reveals that single berries ripen two times faster than previously documented on standard asynchronous samples |
| 胡椒属植物Piper fimbriulatum中显著多样的生物碱骨架 |
Damiani, T. |
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N/A |
Remarkable diversity of alkaloid scaffolds in Piper fimbriulatum |
| 生长素拮抗剂PEO-IAA和生长素运输抑制剂NPA对藓类植物（Physcomitrium patens (Hedw.) Mitt.）配子体发育的影响 |
Robinson, S. R. |
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N/A |
Effects of an auxin antagonist, PEO-IAA, and an auxin transport inhibitor, NPA, on gametophore development in Physcomitrium patens (Hedw.) Mitt. |
| 植物诱导的转录可塑性在广食性和专食性植食者之间存在差异。 |
Wu, J. |
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N/A |
Plant-induced transcriptional plasticity diverges between generalist and specialist herbivores |
| 印度白纹伊蚊种群中的击倒抗性（kdr）突变：携带V1016G、F1534C和F1534L kdr等位基因的单倍型之间缺乏重组 |
Kaur, T. |
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N/A |
Knockdown-resistance (kdr) mutations in Indian Aedes aegypti populations: lack of recombination among haplotypes bearing V1016G, F1534C, and F1534L kdr alleles |
| 白质分数各向异性寿命规范模型：应用于早期精神病 |
Cirstian, R. |
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N/A |
Lifespan Normative Models of White Matter Fractional Anisotropy: Applications to Early Psychosis |
| 下一代测序揭示了在早发性结直肠癌中出现新型生殖系变异的模式。 |
VANDE PERRE, P. |
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N/A |
Next generation sequencing identifies a pattern of novel germline variants in early-onset colorectal cancer |
| 保持轨道：胶原蛋白纤维的排列方向对高剪切力下的血栓形成有显著影响。 |
Melnikova, J. A. |
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N/A |
Staying on track: collagen fibers orientation strongly affects thrombi formation at high shear |
| Pex3促进过氧化物酶体与过氧化物酶体以及过氧化物酶体与脂滴接触点的形成。 |
Amado, L. |
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N/A |
Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites |
| 一种针对牛肝菌（Boletus edulis）的单倍体型解析染色体参考基因组 |
Brejon Lamartiniere, E. |
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N/A |
A haplotype-resolved chromosomal reference genome for the porcini mushroom Boletus edulis |
| 强迫症患者在认知负荷下的心率动态与抗氧化能力 |
Portnova, G. V. |
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N/A |
The heart rate dynamics and antioxidant capacity under cognitive load in Obsessive-Compulsive disorder |
| 驱动蛋白KIF3AC循环内吞的整合素，以极化粘附形成朝向前缘 |
Rockenbach, J. A. |
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N/A |
The kinesin KIF3AC recycles endocytosed integrin to polarize adhesion formation towards the leading edge |
| 温度敏感的皮层凝聚调节三细胞连接处的机械响应 |
Zheng, Q.-h. |
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N/A |
Temperature-sensitive cortical condensation modulates mechano-response at Tricellular Junctions |
| Bicoid-核小体竞争设定了一个由基因组复制所限制的转录浓度阈值。 |
Degen, E. A. |
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N/A |
Bicoid-nucleosome competition sets a concentration threshold for transcription constrained by genome replication |
| 不同的调控元件程序引导小鼠性腺发育过程中性别特异的支持细胞分化。 |
Stevant, I. |
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N/A |
Divergent regulatory element programs steer sex-specific supporting cell differentiation along mouse gonadal development |
| 单细胞转录组学分析显示，经过X射线照射的果蝇翅盘细胞存在异质性，这种异质性与细胞周期状态和细胞位置相关。 |
Cruz, J. |
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N/A |
Single cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location |
| 使用Jax-EPBD高效生成高吞吐量的DNA呼吸特征 |
Inan, T. T. |
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N/A |
Efficient High-Throughput DNA Breathing Features Generation Using Jax-EPBD |
| inVAE：用于生成多元单细胞参考图的条件不变表示学习 |
Aliee, H. |
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N/A |
inVAE: Conditionally invariant representation learning for generating multivariate single-cell reference maps |
| 根-孔隙相互作用，被低估的驱动因素，影响根际结构和根鞘发育 |
Geers-Lucas, M. |
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N/A |
Root-pore interactions, the underestimated driver for rhizosphere structure and rhizosheath development |
| 用于细胞内肽组和小蛋白部分质谱分析的通用工具集 |
Kote, S. |
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N/A |
Universal toolset for mass spectrometric analysis of intracellular peptidome and small protein fraction |
| 传感器运动驱动主动神经元细胞自动机中的突发注意力和可扩展性 |
Kvalsund, M.-K. |
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N/A |
Sensor Movement Drives Emergent Attention and Scalability in Active Neural Cellular Automata |
| 小鼠上丘中的Loom反应依赖于感觉运动背景 |
Zucca, S. |
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N/A |
Loom response in mouse superior colliculus depends on sensorimotor context |
| 创伤性脑损伤的临床前模型中，伽马频段脑电功能网络的拓扑结构、成本和动力学的改变 |
Tsikonofilos, K. |
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N/A |
Alterations in topology, cost and dynamics of gamma-band EEG functional networks in a preclinical model of traumatic brain injury |
| Msp1 和 Pex19-Pex3 协同作用，以实现 Pex15 在过氧化物酶体中的正确定位。 |
Matsumoto, S. |
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N/A |
Msp1 and Pex19-Pex3 cooperate to achieve correct localization of Pex15 to peroxisomes |
| GRASP55通过控制溶酶体酶在高尔基体中的分类，保护了溶酶体的正常功能。 |
Nuechel, J. |
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N/A |
GRASP55 Safeguards Proper Lysosome Function by Controlling Sorting of Lysosomal Enzymes at the Golgi |
| 肠道成纤维细胞异质性：统一RNA测序研究并引入共识驱动的命名法 |
Glisovic, N. |
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N/A |
Intestinal fibroblast heterogeneity: unifying RNA-seq studies and introducing consensus-driven nomenclature |
| 量化H9c2大鼠心肌细胞视黄酸分化的形态学、功能和生化特征 |
York, N. S. |
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N/A |
Quantification of morphological, functional, and biochemical features of H9c2 rat cardiomyoblast retinoic acid differentiation |
| 雷帕霉素诱导的自噬增强了脂质分解并改善了大西洋鲑鱼细胞的脂毒性。 |
Phadwal, K. |
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N/A |
Rapamycin induced autophagy enhances lipid breakdown and ameliorates lipotoxicity in Atlantic salmon cells. |
| 5' HOXD基因在手关节滑膜成纤维细胞中差异性调控基因表达 |
Mirrahimi, M. |
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N/A |
5' HOXD Genes Differentially Regulate Gene Expression of Synovial Fibroblasts in Hand Joints |
| Survivin调节硬度诱导的血管平滑肌细胞迁移 |
Mousso, T. |
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N/A |
Survivin modulates stiffness-induced vascular smooth muscle cell motility |
| 肝脂稳态中线粒体-脂滴相互作用的空间解析重塑。 |
Kang, S. W. S. |
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N/A |
Spatially resolved rewiring of mitochondria-lipid droplet interactions in hepatic lipid homeostasis. |
| NFAT2通过利用表观遗传景观的差异，同时驱动Orai3的转录和蛋白质降解。 |
Raju, S. |
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N/A |
NFAT2 drives both Orai3 transcription and protein degradation by harnessing the differences in epigenetic landscape |
| 冷冻电镜揭示PMEL淀粉样蛋白的致病机制与色素播散综合征相关 |
Yanagisawa, H. |
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N/A |
Cryo-EM of PMEL Amyloids Reveals Pathogenic Mechanism of Pigment Dispersion Syndrome |
| 内体成熟是由通过Na+/H+交换体和pH依赖的Rab GTPase循环进行的向内质子信号传导所调控的。 |
Lee, Y. |
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N/A |
Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling |
| 周细胞将物理创伤信号转化为快速的血管反应。 |
Gelashvili, Z. |
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N/A |
Perivascular macrophages convert physical wound signals into rapid vascular responses |
| 使用快速扩增多重-荧光原位杂交（RAM-FISH）进行空间mRNA定位 |
Banerjee, T. D. |
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N/A |
Spatial mRNA profiling using Rapid Amplified Multiplexed-FISH (RAM-FISH) |
| 海绵-海草共生关系中的互惠营养益处 |
Cardini, U. |
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N/A |
Reciprocal nutritional benefits in a sponge-seagrass association |
| 树枝年龄 2.0：调整不同分类群之间可食性差异的树枝年龄数据，以追踪有蹄类动物在不同地点和时间上的啃食情况 |
Waller, D. M. |
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N/A |
Twig Age 2.0: Adjusting twig age data for differences in palatability among taxa to track ungulate browsing over sites and time |
| Notch信号通路在肺部的多纤毛细胞中稳定了运动纤毛的长度。 |
Guha, A. |
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N/A |
Notch signaling stabilizes lengths of motile cilia in multiciliated cells in the lung |
| 致癌性RAS诱导了一种独特的非经典自噬形式，该形式由P38-ULK1-PI4KB轴介导。 |
Ge, L. |
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N/A |
Oncogenic RAS Induces a Distinctive Form of Non-Canonical Autophagy Mediated by the P38-ULK1-PI4KB Axis |
| APOBEC3B N端和C端结构域之间的调控相互作用 |
Braza, K. |
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N/A |
Regulatory interactions between APOBEC3B N- and C-terminal domains |
| 选择晶体衍射数据的有效且可靠的指标 |
Fu, Z. |
PDF |
N/A |
Effective and Reliable Metrics to Select Crystal Diffraction Data |
| RNA池中的序列基序动态变化 |
Harth-Kitzerow, J. |
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N/A |
Sequence motif dynamics in RNA pools |
| 秀丽隐杆线虫肠道细菌负荷的差异表明宿主与微生物之间存在复杂的相互作用。 |
Boddu, S. S. |
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N/A |
Variance in C. elegans gut bacterial load suggests complex host-microbe dynamics |
| 多盆地Go-Martini方法用于研究蛋白质的构象转变和环境相互作用 |
Yang, S. |
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N/A |
Multiple-Basin Go-Martini for Investigating Conformational Transitions and Environmental Interactions of Proteins |
| GSK3β驱动的ABLIM1与心肌肌联蛋白相互作用调节的分子机制 |
Sun, B. |
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N/A |
Molecular mechanisms of GSK3β-driven modulation of ABLIM1 and titin interactions in cardiac muscle |
| 基准测试人体步态模拟的预测能力。 |
Afschrift, M. |
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N/A |
Benchmarking the predictive capability of human gait simulations. |
| 使用设计表面活性剂蛋白质组装分层多相凝聚物 |
Guan, M. |
PDF |
N/A |
Assembly of Hierarchical Multiphase Condensates Using Designer Surfactant Proteins |
| 一个研究多组分肌动蛋白动力学的广义理论框架 |
Nandi, M. |
PDF |
N/A |
A generalized theoretical framework to investigate multicomponent actin dynamics |
| 一个研究多组分肌动蛋白动力学的广义理论框架 |
Nandi, M. |
PDF |
N/A |
A generalized theoretical framework to investigate multicomponent actin dynamics |
| 基于Mango成像系统的TO1-B染料的截短和“双头”衍生物，具有增强的亮度和选择性以及显著的红移 |
Svetlova, J. I. |
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N/A |
Truncated and "double-headed" derivatives of TO1-B dye for Mango-based imaging systems with increased brightness and selectivity and large Stocks shift |
| 使用DNA条形码库发现结合FKBP12和新靶点的分子胶 |
Michaud, G. A. |
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N/A |
Discovery of molecular glues that bind FKBP12 and novel targets using DNA-barcoded libraries |
| 使用DNA条形码库发现结合FKBP12和新靶点的分子胶 |
Zandi, T. A. |
PDF |
N/A |
Discovery of molecular glues that bind FKBP12 and novel targets using DNA-barcoded libraries |
| 戈谢病中血液和红细胞的计算机生物物理学和流变学 |
Chai, Z. |
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N/A |
In silico biophysics and rheology of blood and red blood cells in Gaucher Disease |
| 转录抑制因子BCL11A的Z0结构域的解决方案结构揭示了蛋白质结合锌指的序列特性 |
Harris, R. E. |
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N/A |
Solution structure of the Z0 domain from transcription repressor BCL11A sheds light on the sequence properties of protein-binding zinc-fingers |
| MuSkeMo：开源软件，用于在Blender中构建、分析和可视化人体和动物的肌肉骨骼模型及其运动 |
van Bijlert, P. A. |
PDF |
N/A |
MuSkeMo: Open-source software to construct, analyze, and visualize human and animal musculoskeletal models and movements in Blender |
| 分子拥挤抑制机械应力驱动的DNA链分离 |
Desai, P. R. |
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N/A |
Molecular Crowding Suppresses Mechanical Stress-Driven DNA Strand Separation |
| KAT6/KAT7的催化抑制增强了Menin抑制剂在MLL白血病中的疗效，并克服了原发性和获得性耐药性。 |
Gordon, S. J. |
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N/A |
Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia |
| 脑膜瘤中的肿瘤相关巨噬细胞：作为独立的不良预后因素，其影响超越了T细胞的益处 |
Lotsch, C. |
PDF |
N/A |
Tumor-Associated Macrophages in Meningiomas: An Independent Prognostic Factor for Poor Survival Outperforming the Benefits of T cells |
| 一种NAMPT抑制剂减少了一种针对5-磷酸核糖-1-焦磷酸结合环的抗体对NAMPT的捕获：这是NAMPT占有率测定的合理依据 |
Shomali, M. |
PDF |
N/A |
An NAMPT Inhibitor Decreases NAMPT Capture by an Antibody Directed against the 5-Phosphoribosyl-1-Pyrophosphate-Binding Loop: A Rational for an NAMPT Occupancy Assay |
| STAT1促进PD-L1激活及淋巴管平滑肌瘤病中的肿瘤生长 |
Olatoke, T. |
PDF |
N/A |
STAT1 Promotes PD-L1 Activation and Tumor Growth in Lymphangioleiomyomatosis |
| 前列腺癌相关成纤维细胞的分泌组分析以识别潜在的治疗靶点 |
Abikar, A. |
PDF |
N/A |
Secretome analysis of cancer-associated fibroblasts from prostate cancer to identify potential therapeutic targets |
| AKR1C介导了HER-2阳性胃癌细胞系对T-Dxd的获得性耐药。 |
wang, d. |
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N/A |
AKR1C mediates the acquired resistance to T-Dxd in a HER-2 positive gastric cancer line |
| 精神病前驱期亚群中的显著网络分离与症状特征 |
Iyer, A. |
PDF |
N/A |
Salience Network Segregation and Symptom Profiles in Psychosis Prodrome Subgroups |
| E-钙粘蛋白的内吞作用促进了非经典的EGFR:STAT信号传导，从而诱导细胞死亡并抑制异染色质化。 |
Ramirez-Moreno, M. |
PDF |
N/A |
E-cadherin endocytosis promotes non-canonical EGFR:STAT signalling to induce cell death and inhibit heterochromatinisation |
| 脂质翻转、O抗原屏蔽及水动力学：通过100-200微秒粗粒化模拟揭示的大肠杆菌外膜蛋白特性 |
Kalenkiewicz, A. |
PDF |
N/A |
Lipid Flipping, O-antigen Shielding, and Water Dynamics Revealed by 100-200 μs Coarse-Grained Simulations of E. coli Outer Membrane Proteins |
| RNA编码物理信息。 |
Seim, I. |
PDF |
N/A |
RNA encodes physical information |
| 合理设计19F NMR标记位点以探测蛋白质结构和相互作用 |
Streit, J. O. |
PDF |
N/A |
Rational design of 19F NMR labelling sites to probe protein structure and interactions |
| 识别中分辨率冷冻电镜密度图中的氨基酸侧链 |
Mondal, D. |
PDF |
N/A |
Recognizing amino acid sidechains in a medium resolution cryo-electron density map |
| 人类RAD52复合物经历相分离，并促进RAD51前联会丝的捆绑和端到端连接。 |
Alshareedah, I. |
PDF |
N/A |
The human RAD52 complex undergoes phase separation and facilitates bundling and end-to-end tethering of RAD51 presynaptic filaments |
| 珊瑚珊瑚虫特异性视蛋白采用了一种新颖的氯离子对抗离子用于光谱调谐 |
Sakai, Y. |
PDF |
N/A |
Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning |
| 对天然结构和化学图谱数据的分析揭示了RNA中的局部稳定性补偿现象。 |
Cornwell-Arquitt, R. L. |
PDF |
N/A |
Analysis of natural structures and chemical mapping data reveals local stability compensation in RNA |
| ColBuilder：交联胶原蛋白纤维的灵活结构生成 |
Monego, D. |
PDF |
N/A |
ColBuilder: Flexible structure generation of crosslinked collagen fibrils |
| 离子液体对泛素稳定性的调控：疏水相互作用的主导作用 |
Shrivastava, A. |
PDF |
N/A |
Ionic Liquid-Induced Modulation of Ubiquitin Stability: The Dominant Role of Hydrophobic Interactions |
| 急性淋巴细胞白血病中的增强子异质性驱动患者间的差异基因表达 |
Smith, A. L. |
PDF |
N/A |
Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression between patients |
| 通过细胞外囊泡优先释放的微小RNA与从导管原位癌向浸润性乳腺癌进展相关 |
Elayapillai, S. P. |
PDF |
N/A |
Preferential Release of microRNAs via Extracellular Vesicles is Associated with Ductal Carcinoma In Situ to Invasive Breast Cancer Progression |
| METCAM/MUC18在鼻咽癌III型的发展中扮演着肿瘤促进者的角色。 |
Liu, Y.-C. |
PDF |
N/A |
METCAM/MUC18 plays a tumor promoter role in the development of nasopharyngeal carcinoma type III |
| 纤维状癌的单细胞多组学分析揭示了重构的细胞间通讯模式和独特的脆弱性 |
Farghli, A. R. |
PDF |
N/A |
Single-cell multi-omic analysis of fibrolamellar carcinoma reveals rewired cell-to-cell communication patterns and unique vulnerabilities |
| 解读与卵巢癌患者不良生存率相关的肿瘤浸润性CD73+调节性γδ T细胞生态系统 |
LAFONT, V. |
PDF |
N/A |
Deciphering the tumor-infiltrating CD73+ regulatory gammadelta T cell ecosystem associated with poor survival of patients with ovarian cancer |
| FAK通过调节糖酵解和线粒体功能，通过肌动蛋白-肌球蛋白收缩性调控胶质母细胞瘤干细胞的能量代谢。 |
Masalmeh, R. H. A. |
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N/A |
FAK modulates glioblastoma stem cell energetics via actomyosin contractility: regulation of glycolysis and mitochondrial function |
| 现代化组织病理学分析：一种用于肠道微菌落存活实验数字图像分析的全自动工作流程 |
Baikalov, A. |
PDF |
N/A |
Modernizing histopathological analysis: a fully automated workflow for the digital image analysis of the intestinal microcolony survival assay |
| DNMT/G9a复合物抑制揭示了急性髓性白血病的表观遗传脆弱性并诱导干扰素反应 |
Schoenefeld, A. |
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N/A |
DNMT/G9a Complex Inhibition Uncovers Epigenetic Vulnerabilities and Induces IFN-Response in Acute Myeloid Leukemia |
| 增强子长链非编码RNA LOC730338限制了对抗淋巴瘤细胞的先天免疫反应，抑制了依赖ADAR2的替代转录。 |
Cascione, L. |
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N/A |
Enhancer lncRNA LOC730338 limits the innate immune response against lymphoma cells, inhibiting ADAR2-dependent alternative transcription. |
| 细胞优先调控细胞质量密度 |
Fu, J. |
PDF |
N/A |
Cells Prioritize the Regulation of Cell Mass Density |
| 通过图神经网络和迁移学习实现对蛋白质分子性质的精确预测 |
Wozniak, S. |
PDF |
N/A |
Accurate Predictions of Molecular Properties of Proteins via Graph Neural Networks and Transfer Learning |
| OASL通过cGAS-STING途径对胃癌中OXA诱导的免疫原性细胞死亡的影响 |
Sun, D. |
PDF |
N/A |
Effect of OASL on OXA-induced immunogenic cell death in gastric cancer via cGAS-STING pathway |
| 三阴性乳腺癌的患者源性异种移植模型能够实现化疗反应的解析和预测。 |
Lei, J. T. |
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N/A |
Patient-Derived Xenografts of Triple-Negative Breast Cancer Enable Deconvolution and Prediction of Chemotherapy Responses |
| CoREST复合物的抑制通过改变RNA剪接促进新抗原表达并增强肿瘤免疫 |
Fisher, R. J. |
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N/A |
CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity |
| 儿童期单侧半球切除术后患者的空间和物体注意能力 |
Robert, S. |
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N/A |
Space- and object-based attention in patientswith a single hemisphere following childhood resection |
| 得克萨斯州中部海岸科帕诺湾、阿拉善湾和红鱼湾底栖有孔虫（玫瑰红染色）的分布情况 |
Barrera, A. |
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N/A |
DISTRIBUTION OF LIVING (ROSE BENGAL STAINED) BENTHIC FORAMINIFERA IN COPANO, ARANSAS, AND REDFISH BAYS, CENTRAL TEXAS COAST |
| 变体集蒸馏 |
Christ, R. |
PDF |
N/A |
Variant Set Distillation |
| 从心脏组织基质或血浆中分离的小细胞外囊泡显示出与年龄相关的货物变化，这些变化有助于慢性心血管疾病的发展。 |
Ronan, G. |
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N/A |
Small Extracellular Vesicles Isolated from Cardiac Tissue Matrix or Plasma Display Distinct Aging-Related Changes in Cargo Contributing to Chronic Cardiovascular Disease |
| 记忆编码的相位重置动力学 |
Colyer, R. A. |
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N/A |
Phase reset dynamics of memory encoding |
| 通路热力学分析假设谷氨酸代谢的变化是调节免疫反应的关键因素 |
Malla, S. |
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N/A |
Pathway Thermodynamic Analysis Postulates Change in Glutamate Metabolism as a Key Factor in Modulating Immune Responses |
| CD4共受体调控性别特异性NK细胞对急性弓形虫感染的反应。 |
Roy, T. |
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N/A |
CD4 Co-Receptor Regulates Sex-Specific NK Cell Responses to Acute Toxoplasma gondii Infection. |
| 种子传播中断限制了热带森林的再生。 |
Fricke, E. C. |
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N/A |
Seed dispersal disruption limits tropical forest regrowth |
| 在小鼠眼中，全反式视黄酸受光和多巴胺的调节。 |
Talwar, S. |
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N/A |
Modulation of all-trans retinoic acid by light and dopamine in the murine eye |
| 皮肤成纤维细胞稳态的改变有助于愈合结果 |
Huang, Y. |
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N/A |
Alteration of skin fibroblast steady state contributes to healing outcomes |
| 从三色堇（Viola odorata）中计算预测的环肽（cyclotides）作为肺炎链球菌（Streptococcus pneumoniae）神经氨酸酶潜在抑制剂的研究 |
Sankar, S. |
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N/A |
Computational prediction of cyclotides from Viola odorata as potential inhibitors against the neuraminidase of Streptococcus pneumoniae |
| 全球多组学分析显示，渐进式跑步机运动对啮齿动物的exerkines有影响。 |
Taha, H. B. |
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N/A |
Global multi-omics analysis of exerkines in progressive treadmill-exercised rodents |
| 任务因素影响在牵张反射中的时间位移 |
Torell, F. |
PDF |
N/A |
Temporal shift in task factor influence across the stretch reflex |
| 通过超局部温度测量法测量的麻醉动物大脑与体温之间的关系 |
Osypov, A. A. |
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N/A |
Relationship between Brain and Body Temperature in Anesthetized Animals Measured by Ultralocal Thermometry |
| 丘脑网状核亚群的生物物理建模及其对网络动力学的差异化贡献 |
Litvak, P. F. |
PDF |
N/A |
Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to network dynamics |
| 皮质类器官中的目标导向学习 |
Robbins, A. S. |
PDF |
N/A |
Goal-Directed Learning in Cortical Organoids |
| 在小鼠体感皮层中的感知选择与运动信号 |
Minamisawa, G. |
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N/A |
Perceptual choice and motor signals in mouse somatosensory cortex |
| 行为和遗传标志物，用于识别芬太尼摄入量增加的易感性。 |
Keady, J. |
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N/A |
Behavioral and genetic markers of susceptibility to escalate fentanyl intake. |
| 多模态单细胞分析揭示了人类药物难治性癫痫中神经元衰老的分子标志物。 |
Ge, Q. |
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N/A |
Multimodal single-cell analyses reveal molecular markers of neuronal senescence in human drug-resistant epilepsy |
| 在戒断初期阻断下丘脑分泌素受体1可减少未来的可卡因需求 |
Espana, R. |
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N/A |
Hypocretin receptor 1 blockade early in abstinence reduces future demand for cocaine |
| 使用EMG驱动的肌肉骨骼模型开发实时神经控制器 |
Thomas, J. B. |
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N/A |
Development of a real-time neural controller using an EMG-driven musculoskeletal model |
| 一种用于线性表位疫苗分析的快速方法揭示了意外的表位标签免疫原性 |
Browne-Cole, K. |
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N/A |
A rapid approach for linear epitope vaccine profiling reveals unexpected epitope tag immunogenicity |
| 虚拟临床试验揭示了靶向肿瘤相关巨噬细胞和小胶质细胞治疗胶质母细胞瘤的显著临床潜力 |
Mongeon, B. |
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N/A |
Virtual clinical trial reveals significant clinical potential of targeting tumour-associated macrophages and microglia to treat glioblastoma |
| 通过遗传亲本分配和PIT标记验证大西洋鲑（Salmo Salar）鳞片读数 |
Utne, K. R. |
PDF |
N/A |
Validating Atlantic salmon (Salmo Salar) scale reading by genetic parent assignment and PIT-tagging |
| 性尺寸二态性与哺乳动物中的雄激素反应数量相关，但仅限于小型体型的物种。 |
Ghione, C. R. |
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N/A |
Sexual size dimorphism correlates with the number of androgen response in mammals, but only in small-bodied species |
| 发育不完全的羽枝增加了早期羽毛的形态多样性 |
Zhang, Y. |
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N/A |
Developmentally Incomplete Barb Rami Increased the Morphological Diversity of Early Feathers |
| 博物馆保护见解：揭示贾巴托小丑蛙（Atelopus ignescens）的灭绝因素 |
Guerra, M. A. |
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N/A |
Museum insights for conservation: Unraveling the Extinction Factors in the Jambato Harlequin Frog, Atelopus ignescens |
| 兰花、天蛾与达尔文再探：天蛾传粉如何推动了旧大陆和新大陆安格科斯类植物的物种形成 |
Farminhao, J. N. |
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N/A |
Orchids, hawkmoths and Darwin revisited: How adaptation to pollination by hawkmoths spurred the speciation of Old and New World angraecoids |
| 使用红外摄像机追踪棉铃虫（鳞翅目：夜蛾科）在性信息素诱捕器周围的飞行行为 |
Duplais, C. |
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N/A |
Tracking Helicoverpa zea (Lepidoptera: Noctuidae) flight behavior with infrared camera around pheromone trap |
| 老鼠在追求食物和休闲时遵循相同的理性原则。 |
Logue, R. S. |
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N/A |
Rats pursue food and leisure following the same rational principles |
| 玻璃化与快速复温在药理学和生物医学研究中对精准切割的肝脏切片的应用 |
Ramesh, S. |
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N/A |
Vitrification and rapid rewarming of precision-cut liver slices for pharmacological and biomedical research |
| 使用卷积神经网络进行挤出式生物打印的自主控制 |
Kelly, D. |
PDF |
N/A |
Autonomous control of extrusion bioprinting using convolutional neural networks |
| 利用配对的生物力学-组织学有限元分析（FEA）建模模拟大型机械活性培养系统（BigMACS），以推导力学生物学设计关系。 |
Schoenborn, S. |
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N/A |
Simulating big mechanically-active culture systems (BigMACS) using paired biomechanics-histology FEA modelling to derive mechanobiology design relationships. |
| 基于环境电离质谱成像的分子数字孪生技术的发展及其在肿瘤外科实时应用中的潜力 |
ZIrem, Y. |
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N/A |
Development of Molecular Digital Twins Based on Ambient Ionization Mass Spectrometry Imaging for Real-Time Application in Oncological Surgery |
| 皮肤等效物中再生的真皮间充质细胞的异质性调节屏障功能和弹性。 |
Kimura, S. |
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N/A |
The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulate barrier function and elasticity. |
| 一种用于类器官成熟自适应智能调制的AI-半机械人系统 |
Liu, R. |
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N/A |
An AI-Cyborg System for Adaptive Intelligent Modulation of Organoid Maturation |
| OrthoHMM：利用隐马尔可夫模型改进直系同源群的推断 |
Steenwyk, J. L. |
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N/A |
OrthoHMM: Improved Inference of Ortholog Groups using Hidden Markov Models |
| 卷积-长短期记忆网络方法用于时间热点捕捞区（CATCH）：一种用于渔业捕捞概率密度时空预测的AI驱动模型 |
Agmata, A. |
PDF |
N/A |
Convolutional-LSTM Approach for Temporal Catch Hotspots (CATCH): An AI-Driven Model for Spatiotemporal Forecasting of Fisheries Catch Probability Densities |
| 模拟类似PPR疾病的扩散以改进监测 |
Apolloni, A. |
PDF |
N/A |
Simulating the diffusion of PPR-like disease to improve surveillanc |
| scPDA：基于液滴的单细胞数据中蛋白质表达的去噪 |
Zhu, O. |
PDF |
N/A |
scPDA: Denoising Protein Expression in Droplet-Based Single-Cell Data |
| 跨多个实验室整合定性和定量数据以进行模型校准 |
Rodriguez, R. B. |
PDF |
N/A |
Integrating qualitative and quantitative data across multiple labs for model calibration |
| SPE-CZE-MS 技术能够定量检测磷酸化肽的仄摩尔浓度。 |
Serrano, L. R. |
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N/A |
SPE-CZE-MS quantifies zeptomole concentrations ofphosphorylated peptides |
| 混合神经微分方程用于模拟生物学中未知机制和状态 |
Whipple, B. |
PDF |
N/A |
Hybrid Neural Differential Equations to Model Unknown Mechanisms and States in Biology |
| 在儿童皮质切除术后视觉皮层的类别选择性的横断面和纵向变化 |
Liu, T. T. |
PDF |
N/A |
Cross-sectional and longitudinal changes in category-selectivity in visual cortex following pediatric cortical resection |
| 运动诱导的AMPK信号转导的差异性转录输出改善了轴突再生和功能恢复 |
Behera, S. |
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N/A |
Exercise-induced differential transcriptional output of AMPK signalling improves axon regeneration and functional recovery |
| 抗体通过配体模拟和变构干扰来破坏细菌的粘附。 |
Hvorecny, K. L. |
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N/A |
Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference |
| 使用旁系同源基因进行系统发育推断可以减轻长枝吸引效应的影响。 |
Smith, M. L. |
PDF |
N/A |
Using paralogs for phylogenetic inference mitigates the effects of long-branch attraction |
| 一种无需标记的基于纳米孔的阻抗传感器，用于十分钟内检测SARS-CoV-2 |
Meng, Z. |
PDF |
N/A |
A Label-free Nanowell-based Impedance Sensor for Ten-minute SARS-CoV-2 Detection |
| 解读结直肠癌与肝细胞相互作用：一种用于探索肝肿瘤微环境中代谢串扰的多组学平台 |
Nelson, A. B. |
PDF |
N/A |
Deciphering Colorectal Cancer-Hepatocyte Interactions: A Multiomic Platform for Interrogation of Metabolic Crosstalk in the Liver-Tumor Microenvironment |
| mRNA-1273和NVX-CoV2373 COVID-19疫苗多克隆抗体反应的结构血清学 |
Bangaru, S. |
PDF |
N/A |
Structural serology of polyclonal antibody responses to mRNA-1273 and NVX-CoV2373 COVID-19 vaccines |
| 悬浮含菌模拟呼吸道液滴的蒸发与致病性：在不同相对湿度和蒸发阶段的研究 |
Agharkar, A. N. |
PDF |
N/A |
Evaporation and pathogenesis of levitated bacteria-laden surrogate respiratory fluid droplets: At different relative humidity and evaporation stages |
| 万古霉素耐药的肠球菌通过占据特定的营养和代谢物定义的肠道生态位，在抗生素处理后的肠道中定植。 |
King, O. G. |
PDF |
N/A |
Vancomycin-resistant Enterococcus colonise the antibiotic-treated intestine by occupying distinct nutrient- and metabolite-defined intestinal niches |
| 生境过滤而非微生物群起源控制土壤中微生物群移植的结果 |
Causevic, S. |
PDF |
N/A |
Habitat filtering but not microbiota origin controls microbiome transplant outcomes in soil |
| 探索共生大肠杆菌在体外调节抗生素抗性沙门氏菌海德堡株转录组变化的研究 |
Kariyawasam, S. |
PDF |
N/A |
Exploring Transcriptomic Changes in Antibiotic-Resistant Salmonella Heidelberg Modulated by Commensal Escherichia coli in Vitro |
| 金黄色葡萄球菌COL：一种非典型的MRSA模型菌株，表现出缓慢生长和抗生素耐受性 |
Stevens, C. E. |
PDF |
N/A |
Staphylococcus aureus COL: An Atypical Model Strain of MRSA that Exhibits Slow Growth and Antibiotic Tolerance |
| 沙门氏菌鼠伤寒杆菌通过操控突触融合蛋白7在宿主细胞的内吞-溶酶体运输中导航 |
Vij, R. |
PDF |
N/A |
Salmonella Typhimurium Manipulates Syntaxin 7 to Navigate Endo-Lysosomal Trafficking in Host Cells |
| 一种新型膜应激反应，通过ClpP蛋白酶靶向DnaA起始因子来阻止染色体复制 |
Saxena, R. |
PDF |
N/A |
A novel membrane stress-response that blocks chromosomal replication by targeting the DnaA initiator via the ClpP protease |
| MetaBiome：一种多尺度模型，整合基于代理的建模和代谢网络，揭示黏膜微生物群落中的空间调控 |
Aminian-Dehkordi, J. |
PDF |
N/A |
MetaBiome: A Multiscale Model Integrating Agent-Based Modeling and Metabolic Networks Reveals Spatial Regulation in Mucosal Microbial Communities |
| 一种新型抗真菌相互作用测试方法：评估白色念珠菌临床分离株中的协同作用与拮抗作用。 |
Lundvik, H. |
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N/A |
A Novel Method for Testing Antifungal Interactions: Assessing Synergy and Antagonism in Candida albicans Clinical Isolates. |
| 微生物群落中的移民概率和持续时间 |
Curtis, T. P. |
PDF |
N/A |
The probability and duration of immigration in microbial communities |
| 维持伴侣蛋白Spy中的甲硫氨酸残基处于还原状态对于周质蛋白质稳态至关重要。 |
Loiseau, L. |
PDF |
N/A |
Maintaining the methionine residues of the chaperone Spy in a reduced state is crucial for periplasmic proteostasis. |
| 增强产量与温和纯化HIV用于病毒体成熟过程的冷冻电镜断层分析。 |
Preece, B. |
PDF |
N/A |
Enhanced Yield and Gentle Purification of HIV for Cryo-Electron Tomography Analysis of Virion Maturation. |
| spotPCR：一种利用独特分子标识符快速高效地索引单个模板分子的方法 |
Limberis, J. D. |
PDF |
N/A |
spotPCR: A Rapid and Efficient Approach for Indexing Individual Template Molecules using Unique Molecular Identifiers |
| 增强RNA递送：NeoLNP转染试剂的实用见解 |
Chen, X. |
PDF |
N/A |
Enhancing RNA Delivery: Practical Insights into NeoLNP Transfection Reagent |
| 多聚磷酸盐作为超级增强子复合物的新型调控因子：相分离的破坏与基因表达 |
Yang, Z. |
PDF |
N/A |
Polyphosphate as a Novel Regulator of Super-Enhancer Complexes: Disruption of Phase Separation and Gene Expression |
| Sir2蛋白对于rDNA在静止状态下特有的凝聚三维染色质结构是必需的。 |
Cucinotta, C. |
PDF |
N/A |
Sir2 is required for the quiescence-specific condensed three-dimensional chromatin structure of rDNA |
| 年龄相关的DNA甲基化变化模式 |
Chen, K. Y. |
PDF |
N/A |
Age-Related Patterns of DNA Methylation Changes |
| 基于在二聚体界面引入二硫键和B因子分析，对提高ZHD101热稳定性的合理分子设计 |
DING, W. |
PDF |
N/A |
Rational molecular design for improved ZHD101 thermal stability based on the introduction of disulfide bonds at the dimer interface and B-factor analysis |
| 林蛙在免疫基因表达和能量储存表型上的组成性差异与冬季环境共同变化 |
Vaziri, G. J. |
PDF |
N/A |
Constitutive differences in immune gene expression and energy storage phenotypes co-vary with winter environment in wood frogs |
| 红点豆娘（Hetaerina spp.）非生态物种形成的时空动态 |
Patterson, C. |
PDF |
N/A |
Spatiotemporal dynamics of non-ecological speciation in rubyspot damselflies (Hetaerina spp.) |
| 哺乳动物热休克蛋白A4家族直向同源物Hsc70Cb在果蝇D. melanogaster的精子发生过程中对两个阶段是必需的。 |
Houston, B. J. |
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N/A |
Mammalian heat shock protein A4 family ortholog Hsc70Cb is required for two phases of spermatogenesis in D. melanogaster |
| 长读基因组学揭示了一种双核真菌中广泛的核特异性进化和等位基因特异性表达 |
Tam, R. |
PDF |
N/A |
Long-read genomics reveal extensive nuclear-specific evolution and allele-specific expression in a dikaryotic fungus |
| 糖皮质激素受体的多聚化途径 |
Estebanez-Perpina, E. |
PDF |
N/A |
The multimerization pathway of the glucocorticoid receptor |
| 通过自上而下蛋白质组学对跨物种心室肌球蛋白轻链1中S-谷胱甘肽化的深入表征 |
Chapman, E. A. |
PDF |
N/A |
In-depth Characterization of S-Glutathionylation in Ventricular Myosin Light Chain 1 Across Species by Top-Down Proteomics |
| 结核分枝杆菌EsxG·EsxH（TB9.8·TB10.4）肽作为亚单位疫苗，用于增强卡介苗（BCG）在肺结核实验模型中的接种效果。 |
Martinez-Olivares, C. E. |
PDF |
N/A |
Mycobacterial EsxG·EsxH (TB9.8·TB10.4) peptides as a subunit vaccine to booster BCG vaccination in an experimental model of pulmonary Tuberculosis |
| 超稳定且多功能的微卫星FoxP3集合 |
Leng, F. |
PDF |
N/A |
Ultrastable and Versatile FoxP3 Ensembles on Microsatellites |
| 一种独特的自体荧光分布模式标志着植物细胞壁的酶解破坏 |
Hossein Khani, S. |
PDF |
N/A |
A Distinct Autofluorescence Distribution Pattern Marks Enzymatic Deconstruction of Plant Cell Wall |
| 钙调蛋白结合是钙介导的TRPA1脱敏作用所必需的。 |
Sanders, J. H. |
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N/A |
Calmodulin binding is required for calcium mediated TRPA1 desensitization |
| 山梨酸通过I类HDACs的非经典活性诱导赖氨酸山梨酰化，以调控炎症基因的表达 |
Sin, Y.-C. |
PDF |
N/A |
Sorbate Induces Lysine Sorbylation Through Non-Canonical Activities of Class I HDACs to Regulate the Expression of Inflammation Genes |
| 人类酸感应离子通道1a的构象可塑性 |
Cahill, J. |
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Conformational plasticity of human acid-sensing ion channel 1a |
| 利用高吞吐量细菌表达分泌型scFv-ompY融合蛋白，对tilvestamab（一种抗AXL功能阻断抗体）的抗原结合位点进行映射。 |
Christakou, E. |
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Paratope mapping of tilvestamab, an anti-AXL function blocking antibody, using high-throughput bacterial expression of secreted scFv-ompY fusion proteins |
| 使用INDEGRA进行无偏差转录组比较的高精度RNA完整性定义 |
Cleynen, A. |
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High-Accuracy RNA Integrity Definition for Unbiased Transcriptome Comparisons with INDEGRA |
| 多尺度单细胞评估特发性肺纤维化中的纤维化生态位 |
Liu, B. |
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Multiscale single-cell assessment of the fibrotic niche in idiopathic pulmonary fibrosis |
| 设计具有氨酰-tRNA合成酶活性的核酶 |
Gan, G. |
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Engineering a ribozyme with aminoacyl-tRNA synthetase activity |
| 多组学分析与牛（Bos taurus）基因组规模代谢重构，以优化培养肉的生产 |
Lee, J. |
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Multi-omics analysis and genome-scale metabolic reconstruction of cattle Bos taurus for optimal production of cultured meat |
| 在两种密切相关的鹿鼠物种（Peromyscus maniculatus和P. leucopus）中的听力研究 |
Joseph, L. |
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Hearing in Two Closely Related Peromyscus Species (Peromyscus maniculatus and P. leucopus) |
| 动态细胞命运可塑性和组织整合推动功能性滑膜关节再生 |
Blumenkrantz, M. |
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Dynamic cell fate plasticity and tissue integration drive functional synovial joint regeneration |
| 人类卵母细胞中的线粒体DNA突变会受到频率依赖性选择的影响，但不会随年龄增长而增加。 |
Arbeithuber, B. |
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Mitochondrial DNA mutations in human oocytes undergo frequency-dependent selection but do not increase with age |
| 用于蓝藻细胞分割与分类的机器学习模型 |
Huffine, C. A. |
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Machine Learning Models for Segmentation and Classification of Cyanobacterial Cells |
| 夜行性斗牛蚁（Myrmecia midas）在没有成功的情况下运行路线的复杂性 |
deeti, s. |
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Intricacies of running a route without success in night-active bull ants (Myrmecia midas) |
| 丹麦猪群中重组A(H1N1)流感病毒的迅速激增及其人畜共患潜力 |
Ryt-Hansen, P. |
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Rapid Surge of Reassortant A(H1N1) Influenza Viruses in Danish Swine and their Zoonotic Potential |
| 分类学的时间机器 |
Davis-Richardson, A. |
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A Time Machine for Taxonomy |
| 通过对外周血的跨疾病建模，识别出可预测阿尔茨海默病的2型糖尿病生物标志物。 |
Ball, B. K. |
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Cross-disease modeling of peripheral blood identifies biomarkers of type 2 diabetes predictive of Alzheimer's disease |
| 对强光暴露引起的打喷嚏反应：一个光敏感性打喷嚏者的案例研究 |
Bickerstaff, L. |
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Sneezing in response to bright light exposure: A case study in a photic sneezer |
| 频率跟随反应揭示的与年龄相关的神经相位锁定能力下降，对包络和时间精细结构的锁定：可能是影响言语可懂度的耳蜗突触病变的一个潜在标志。 |
Ponsot, E. |
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Age-related decline in neural phase-locking to envelope and temporal fine structure revealed by frequency following responses: A potential signature of cochlear synaptopathy impairing speech intelligibility |
| 食品来源化合物延长冷冻人乳的保质期 |
Silpe, J. E. |
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Food-Derived Compounds Extend the Shelf-Life of Frozen Human Milk |
| 使用新型Klhl14-Cre小鼠系选择性靶向皮质脊髓神经元的一个特定亚群，使得从发育到成熟阶段的分子和解剖学研究成为可能。 |
Lustig, J. |
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Selective Targeting of a Defined Subpopulation of Corticospinal Neurons using a Novel Klhl14-Cre Mouse Line Enables Molecular and Anatomical Investigations through Development into Maturity |
| 你在说什么？人类大脑中言语主题的表征 |
Boncz, A. |
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What are you talking about? Representation of the Topic of Speech in the Human Brain |
| 记忆印迹的解构揭示了在学习过程中招募的不同神经元集群 |
Pouget, C. |
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Deconstruction of a memory engram reveals distinct ensembles recruited at learning |
| 认知努力与奖励。任务时间和多巴胺能及胆碱能基质参与的功能性成像。 |
Orsini, C. |
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Cognitive effort and reward. Functional imaging of time on task and the involvement of dopaminergic and cholinergic substrates |
| 从人类到蠕虫，所有的核糖体RNA和45S间隔区都充满了生物体特有的基序，这些基序的其他副本主要存在于大量神经系统基因中，其中包括许多与人类疾病相关的基因。 |
Rigoutsos, I. |
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All ribosomal RNAs and 45S spacers from humans to worms are packed with organism-specific motifs whose other copies are found predominantly in numerous nervous system genes including many associated with human disorders |
| 利用单核多组学技术对癫痫中伴有少突胶质细胞增生的轻度皮质发育不良的细胞类型进行映射 |
Galvao, I. C. |
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Cell type mapping of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy using single-nucleus multiomics |
| 有蹄类动物的个性和人类盾牌效应共同导致了长距离迁徙的减少。 |
Cotterill, G. |
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Ungulate personality and the human shield contribute to long-distance migration loss |