| 杆状细菌荧光假单胞菌SBW25的球形mreB缺失突变体的进化救援 |
Yulo, P. R. |
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N/A |
Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25 |
| 机械压缩力增加了乳腺癌和胰腺癌细胞中的PI3K输出信号。 |
Di-Luoffo, M. |
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N/A |
Mechanical compressive forces increase PI3K output signaling in breast and pancreatic cancer cells |
| 一种依赖于Hfq的转录后机制微调了大肠杆菌中RecB的表达 |
Kalita, I. |
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N/A |
An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli |
| 重新审视替代负荷:高比例的死亡可能是选择性的 |
Matheson, J. D. |
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N/A |
Substitution load revisited: a high proportion of deaths can be selective |
| 六亚甲基二醇对FUS相分离影响的分子洞察 |
Zheng, T. |
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N/A |
Molecular insights into the effect of hexanediol on FUS phase separation |
| 突触对胆碱能投射神经元的失调导致在5种果蝇帕金森模型中出现嗅觉功能障碍。 |
Pech, U. |
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N/A |
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models |
| 眼跳前中央凹预测的幅度和时间进程取决于眼跳目标的显著性。 |
Kroell, L. M. |
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N/A |
The magnitude and time course of pre-saccadic foveal prediction depend on the conspicuity of the saccade target |
| 一个新的通用树形指数系统 |
Noble, R. J. |
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N/A |
A new universal system of tree shape indices |
| 成年果蝇大脑和身体中的空间转录组学 |
Janssens, J. |
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N/A |
Spatial transcriptomics in the adult Drosophila brain and body |
| 感知与注意力对意识访问的损害:尽管任务表现相同,但神经机制不同 |
Noorman, S. |
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N/A |
Perceptual versus attentional impairments of conscious access: Distinct neural mechanisms despite equal task performance |
| 一种用于快速DNA片段计数和基因分型的模糊序列发生器 |
Zhou, W. |
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N/A |
A fuzzy sequencer for rapid DNA fragment counting and genotyping |
| 人类第二视觉区域中颜色、视差和自然纹理的中尺度功能组织与连接性 |
Ai, H. |
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N/A |
Mesoscale functional organization and connectivity of color, disparity, and naturalistic texture in human second visual area |
| 一个用于自动和广义突触事件分析的深度学习框架 |
O'Neill, P. S. |
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N/A |
A deep learning framework for automated and generalized synaptic event analysis |
| 基于记忆的偏好的主动和被动构建 |
Nicholas, J. |
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N/A |
Proactive and reactive construction of memory-based preferences |
| 大规模骨骼肌单核多组学分析揭示了广泛的上下文特异性遗传调控 |
Varshney, A. |
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N/A |
Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation |
| prestin对氯离子的结合并不会影响小鼠外毛细胞中极高频率的复杂非线性电容(cNLC)。 |
Bai, J.-P. |
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N/A |
Chloride binding to prestin does not influence very high-frequency complex nonlinear capacitance (cNLC) in the mouse outer hair cell |
| 揭示先天性耳聋对个体大脑组织的影响 |
Amaral, L. |
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N/A |
Unraveling the impact of congenital deafness on individual brain organization |
| 孕期神经生物学变化的纵向研究 |
Niu, Y. |
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N/A |
Longitudinal Investigation of Neurobiological Changes Across Pregnancy |
| 用于从文献中提取生物学证据的Lit-OTAR框架 |
Tirunagari, S. |
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N/A |
Lit-OTAR Framework for Extracting Biological Evidences from Literature |
| 附睾在受精之外的贡献:CRISP1和CRISP3对精子DNA完整性和早期胚胎发育的相关性 |
Sulzyk, V. |
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N/A |
Contribution of the epididymis beyond fertilization: relevance of CRISP1 and CRISP3 for sperm DNA integrity and early embryo development |
| 解读延长寿命干预的时间与影响:时间效能分析器区分早期、中年和衰老阶段的效能 |
Jiang, N. |
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N/A |
Deciphering the Timing and Impact of Life-extending Interventions: Temporal Efficacy Profiler Distinguishes Early, Midlife, and Senescence Phase Efficacies |
| 一个多功能的个人信息检索框架,用于评估个人资料的强度和相似度。 |
Kalinin, A. A. |
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N/A |
A versatile information retrieval framework for evaluating profile strength and similarity |
| 拟南芥FCA凝聚体在RNA 3'端加工中的体内特性 |
Jang, G.-J. |
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N/A |
In vivo properties of Arabidopsis FCA condensates involved in RNA 3' processing |
| 凝聚蛋白IDC、H4K20me1及核周锚定共同维持秀丽隐杆线虫X染色体的抑制状态。 |
Trombley, J. |
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N/A |
Condensin IDC, H4K20me1, and perinuclear tethering maintain X chromosome repression in C. elegans |
| 第六层皮层间神经元是大脑半球内和大脑半球间反馈的主要途径。 |
Weiler, S. |
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N/A |
Layer 6 corticocortical neurons are a major route for intra and interhemispheric feedback |
| 饮食预测了大西洋鲑鱼在整个生命周期中的表现权衡 |
Aykanat, T. |
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N/A |
Diet predicts performance trade-offs along Atlantic salmon ontology |
| 跨组织性别偏倚基因表达揭示了三刺鱼鳃中意想不到的差异。 |
Sylvestre, F. |
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N/A |
Sex-biased gene expression across tissues reveals unexpected differentiation in the gills of the threespine stickleback |
| 放线菌素D和硼替佐米破坏维尔姆斯肿瘤中的蛋白质稳态 |
Tiburcio, P. D. B. |
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N/A |
Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor |
| 多发性硬化进展中的性别差异单细胞图谱 |
Soler-Saez, I. |
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N/A |
Single cell landscape of sex differences in the progression of multiple sclerosis |
| 一种开花时间可塑性的反应规范揭示了玉米适应性的生理痕迹 |
Drouault, J. |
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N/A |
A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation |
| 加利福尼亚沿海湿地中沿陆地-海洋断面的隐匿甲烷循环和甲基营养代谢的空间证据 |
Krause, S. J. E. |
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N/A |
Spatial evidence of cryptic methane cycling and methylotrophic metabolisms along a land-ocean transect in a California coastal wetland |
| 在干旱胁迫下,高粱根部在营养生长期内的转录变化和微生物群动态 |
Kabir, A. H. |
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N/A |
Transcriptional shifts and microbiome dynamics in sorghum roots during vegetative growth under drought stress |
| Amidase和Lysozyme在TseP中的双重功能揭示了Type VI分泌系统中一个新的嵌合效应因子家族 |
Wang, Z.-H. |
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N/A |
Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System |
| 普通狨猴利用身体姿势作为一种多功能信号,用于发起、维持和调整社交游戏。 |
Adriaense, J. E. C. |
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N/A |
Common marmosets use body posture as multi-functional signal to solicit, maintain, and modify social play |
| 致癌代谢物D-2-羟基戊二酸在IDH突变型胶质瘤中促进控制小胶质细胞激活的谱系特异性增强子的DNA高甲基化。 |
Laurenge, A. |
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N/A |
The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas |
| GPRC6A作为一种新型鲜味受体,通过鸟氨酸增强味觉偏好。 |
Yamamoto, T. |
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GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine |
| 为功能性神经成像创建基于解剖学、标准化、可定制且可三维打印的头帽 |
McCann, A. |
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N/A |
Creating anatomically-derived, standardized, customizable, and three-dimensional printable head caps for functional neuroimaging |
| 脂质囊泡中膜弯曲与拉伸的耦合关系 |
Wennerström, H. |
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N/A |
On the coupling between membrane bending and stretching in lipid vesicles |
| 灵活且强大的细胞类型注释,适用于高度多重化的组织图像 |
Sun, H. |
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N/A |
Flexible and robust cell type annotation for highly multiplexed tissue images |
| LM-Merg并:一种用于合并逻辑模型的流程,应用于基因调控 |
Li, L. X. |
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N/A |
LM-Merger: A workflow for merging logical models with an application to gene regulation |
| LM-Merg并:一种用于合并逻辑模型的流程,应用于基因调控 |
Li, L. X. |
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N/A |
LM-Merger: A workflow for merging logical models with an application to gene regulation |
| 通过工程改造的甲烷八叠球菌(Methanosarcina acetivorans)从一碳和二碳化合物中生产倍半萜烯红没药烯。 |
Mentrup, A. |
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N/A |
Production of the sesquiterpene bisabolene from one- and two carbon compounds in an engineered Methanosarcina acetivorans |
| 利用扩散磁共振成像技术在体绘制人类大脑皮层微观结构图 |
Sadikov, A. |
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N/A |
Mapping the Microstructure of Human Cerebral Cortex In Vivo with Diffusion MRI |
| 生物信息学:整合阴性对照以获得优质数据 |
van Nues, R. W. |
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N/A |
Bio-informatics: Integrate negative controls to get the good data |
| 轴突特异性微管调控驱动感觉神经元轴突的不对称再生 |
Costa, A. C. |
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N/A |
Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons |
| 冰与气:年轻北美鹅掌楸叶片中冻融栓塞与冻结扩散的可视化 |
Johnson, K. M. |
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N/A |
Ice and air: Visualisation of freeze-thaw embolism and freezing spread in young L. tulipifera leaves |
| 使用基于模型的fMRI技术,将视觉对比敏感度和视觉损失在整个视野范围内进行映射。 |
Chow-Wing-Bom, H. T. |
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N/A |
Mapping Visual Contrast Sensitivity and Vision Loss Across the Visual Field with Model-Based fMRI |
| 叶片大小决定了玉米中由损伤和植食性昆虫诱导的挥发性物质的释放。 |
Waterman, J. M. |
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N/A |
Leaf size determines damage- and herbivore-induced volatile emissions in maize |
| iModMix:多组学数据的综合模块分析 |
Narvaez-Bandera, I. Y. |
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N/A |
iModMix: Integrative Module Analysis for Multi-omics Data |
| 对涡虫再生特异性的比较分析揭示了轴向cWnt信号梯度对组织极性的贡献。 |
Cleland, J. P. |
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N/A |
A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient. |
| 规范模型揭示了前青春期精神病理学维度中明显的皮层异常。 |
Deng, Q. |
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N/A |
Normative models reveal distinct cortical abnormalities to dimensions of psychopathologies in preadolescents |
| 葡萄糖-6-磷酸酶对于果蝇精子的细胞器重组、能量代谢和运动能力是必需的。 |
Hedjazi, S. |
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N/A |
Glucose-6-phosphatase is required for organelle reorganization, energy metabolism and motility of Drosophila sperm |
| 玉米及相关物种中生殖屏障的分子进化 |
Cryan, E. |
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N/A |
Molecular evolution of a reproductive barrier in maize and related species |
| 系统生物学的通用微分方程:当前状态与开放问题 |
Philipps, M. |
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N/A |
Universal differential equations for systems biology: Current state and open problems |
| 使用AlphaFold2预测肽的结构构象 |
Ille, A. M. |
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N/A |
Prediction of peptide structural conformations with AlphaFold2 |
| 多组学分析揭示了跨多种多发性神经病变的人类腓肠神经特征 |
Heming, M. |
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N/A |
Multi-omic characterization of human sural nerves acrosspolyneuropathies |
| 介导视交叉上核昼夜节律同步的功能性脑连接组 |
Nikhil, K. L. |
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N/A |
The Functional Connectome Mediating Circadian Synchrony in the Suprachiasmatic Nucleus |
| 从整合的转录组数据集中推断基因-通路关联:一种用于四膜虫的交互式基因网络浏览器 |
Bertagna, M. A. |
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N/A |
Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for Tetrahymena thermophila |
| 伤寒沙门氏菌的伤寒毒素在急性伤寒热期间引发了宿主的抗菌反应。 |
Srour, S. |
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N/A |
Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever |
| 轴突起始段几何形态的可变性及其对海马锥体细胞功能的影响 |
Stevens, N. A. |
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N/A |
Variability of axon initial segment geometry and its impact on hippocampal pyramidal cell function |
| 在鱼类多样性中,基因表达对免疫刺激的宏观进化变化 |
Flanagan, B. A. |
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N/A |
Macroevolutionary changes in gene expression response to an immune stimulus across the diversity of fishes |
| 当蝙蝠仅依赖回声定位时,如何从拥挤的群体中离开 - 一种建模方法 |
Mazar, O. |
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N/A |
How bats exit a crowded colony when relying on echolocation only - a modeling approach |
| CAR-T细胞疗法临床试验的临床前模型预测价值:一项系统综述和荟萃分析 |
Andreu-Sanz, D. |
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N/A |
Predictive value of preclinical models for CAR-T cell therapy clinical trials: a systematic review and meta-analysis |
| 协同神经回路与新颖性及目标导向行为的关联 |
Elliott, B. L. |
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N/A |
Synergistic Neural Circuits for Novelty and Goal-Directed Behavior |
| 神经元功能中的高阶相互作用:从基因到生物物理模型中的离子电流 |
Reva, M. |
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N/A |
Higher-Order Interactions in Neuronal Function: From Genes to Ionic Currents in Biophysical Models |
| 尽管人口数量有所恢复,但白头海雕的基因组仍在持续退化。 |
Fontsere, C. |
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N/A |
Persistent genomic erosion in whooping cranes despite demographic recovery |
| 生存蓝图:蓝斑蜻蜓作为城市适应的典范 |
Tolman, E. R. |
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N/A |
The Blueprint for Survival: The Blue Dasher Dragonfly as a Model for Urban Adaptation |
| 生存蓝图:蓝斑蜻蜓作为城市适应的典范 |
Tolman, E. R. |
PDF |
N/A |
The Blueprint for Survival: The Blue Dasher Dragonfly as a Model for Urban Adaptation |
| 前所未有的雌性偏倚突变在指猴中出现 |
Wang, R. J. |
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N/A |
Unprecedented female mutation bias in aye-ayes |
| 探索多拷贝质粒适应性动力学的系统:拷贝数和突变率在进化结果中的作用 |
Pisera, A. |
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N/A |
A System to Explore the Adaptive Dynamics of Multicopy Plasmids: The Role of Copy Number and Mutation Rate in Evolutionary Outcomes |
| 蚊子根据微孢子虫感染的动态进行自我治疗。 |
Zeferino, T. G. |
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N/A |
Mosquitoes self-medicate according to the dynamics of a microsporidian infection |
| 控制蝴蝶银色虹彩的适应性多态性的遗传基础 |
Livraghi, L. |
PDF |
N/A |
Genetic basis of an adaptive polymorphism controlling butterfly silver iridescence |
| 保存的Peromyscus属物种标本头部和耳廓形态的变异及其对听觉功能的启示 |
Sergott, C. E. |
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N/A |
VARIATION IN HEAD AND PINNA MORPHOLOGY OF PRESERVED PEROMYSCUS SPP. SPECIMENS AND IMPLICATIONS FOR AUDITORY FUNCTION |
| 在非洲大猿类物种形成早期,片段重复的不完全谱系分选定义了人类2号染色体的融合位点。 |
Jiang, X. |
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N/A |
Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciation |
| 空间药物不对称性调控抗性进化下的表型多样性-迁移关系 |
Hu, Z. |
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N/A |
Spatial drug asymmetry modulates phenotypic diversity-migration relationships under resistance evolution |
| GPCRchimeraDB:一个用于协助设计嵌合G蛋白偶联受体(GPCRs)的数据库 |
Crauwels, C. |
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N/A |
GPCRchimeraDB: A database of chimeric G-Protein Coupled Receptors (GPCRs) to assist their design |
| 多层组织中干细胞命运决定的生物力学 |
Sahu, P. |
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N/A |
Biomechanics of stem cell fate decisions in multilayered tissues |
| 自闭症谱系障碍个体中,后侧脾状复合体表现出非典型的场景选择性 |
Persichetti, A. S. |
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N/A |
Atypical scene-selectivity in the retrosplenial complex in individuals with autism spectrum disorder |
| 细胞分裂依赖的HMR-1/钙粘蛋白扭转调控秀丽隐杆线虫中首次左右对称性破缺事件 |
Khor, M. J. |
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N/A |
Cytokinesis-dependent twisting of HMR-1/Cadherin regulates the first left-right symmetry-breaking event in Caenorhabditis elegans |
| 对灵长类胚胎体中直系同源细胞类型的鉴定和比较显示了标记基因转移性的局限性。 |
Jocher, J. |
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N/A |
Identification and comparison of orthologous celltypes from primate embryoid bodies shows limits of marker gene transferability |
| 一种CRISPR相关Rossman折叠环核酸酶与腺苷脱氨酶的融合蛋白通过别构作用将ATP转化为ITP |
Whyms, C. T. |
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N/A |
A CRISPR-associated Rossman-fold Ring Nuclease and Adenosine Deaminase Fusion Allosterically Converts ATP to ITP |
| 在果蝇卵子发生过程中,发育调控的肌动蛋白-微管交叉对话 |
Chou, W.-C. |
PDF |
N/A |
Developmentally regulated actin-microtubule crosstalk in Drosophila oogenesis |
| 半胱氨酸反应性共价RNF4配体CCW16通过激活ROS信号传导诱导AML细胞发生铁死亡。 |
Mueller, S. |
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N/A |
The cysteine-reactive covalent RNF4 ligand CCW16 induces ferroptosis in AML cells by activation of ROS signaling |
| 形态发生约束在类原肠胚发育中的作用:对小鼠原肠形成的影响 |
Fiuza, U.-M. |
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N/A |
Morphogenetic constrains in the development of gastruloids: implications for mouse gastrulation |
| 在斑马鱼胚胎发生过程中利用Ace2N-mNeon探索生物电 |
Wu, Z. |
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N/A |
Exploring Bioelectricity with Ace2N-mNeon during Zebrafish Embryogenesis |
| 粘附调控的胶质微环境力学调节神经干细胞的增殖潜能 |
Cristina, A. S. |
PDF |
N/A |
Adhesion-Controlled Mechanics of the Glial Niche Regulate Neural Stem Cell Proliferative Potential |
| 珊瑚礁栖息地的复杂性降低,导致当地光照的可用性和多样性减少。 |
Brambilla, V. |
PDF |
N/A |
Coral reef habitat complexity decreases and diversifies local availability of light |
| 端粒到端粒基因组组装揭示了沃尔巴克氏体驱动的性特异性人口统计学,并对锯蜂中的费希尔原理提出了挑战 |
Zhang, M. |
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N/A |
Telomere-to-Telomere Genome Assembly Uncovers Wolbachia-Driven Sex-Specific Demography and Challenges Fisher's Principle in a Sawfly |
| 因果关系的考虑可以决定机器学习辅助的全基因组关联研究(GWAS)的效用。 |
Mukherjee, S. |
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N/A |
Causal considerations can determine the utility of machine learning assisted GWAS |
| 一个优化的方案,用于在微藻Chlamydomonas reinhardtii中相对定量ATP和多磷酸盐 |
Israelievitch, E. |
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N/A |
An optimised protocol for the relative quantification of ATP and polyphosphates in the microalga Chlamydomonas reinhardtii |
| 一个使用大型语言模型(LLMs)进行SARS-CoV-2蛋白质序列比较的无监督框架 |
Littlefield, S. B. |
PDF |
N/A |
An unsupervised framework for comparing SARS-CoV-2 protein sequences using LLMs |
| SeuratIntegrate:一个R包,用于简化与Seurat集成方法的使用 |
Specque, F. |
PDF |
N/A |
SeuratIntegrate: an R package to facilitate the use of integration methods with Seurat |
| 基于肿瘤内微生物组的肿瘤生存指数在泛癌尺度上预测免疫相互作用和药物敏感性 |
Gao, Y. |
PDF |
N/A |
Intra-tumor microbiome-based tumor survival indices predict immune interaction and drug sensitivity on pan-cancer scale |
| ggrain - 一个用于绘制雨云图的 ggplot2 扩展 |
Judd, N. |
PDF |
N/A |
ggrain - a ggplot2 extension for raincloud plots |
| 纵向评估轻度认知障碍向阿尔茨海默病痴呆的转化:来自神经心理学测试和电生理学的观察与机制 |
Dunstan, D. M. |
PDF |
N/A |
Longitudinal assessment of the conversion of mild cognitive impairment into Alzheimer's dementia: Observations and mechanisms from neuropsychological testing and electrophysiology |
| 支架蛋白CasL通过限制膜起泡来调节T细胞迁移。 |
Kurtz, L. A. |
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N/A |
The scaffold protein CasL regulates T cell migration by restricting membrane blebbing |
| 多尺度分析与功能验证:骨骼疾病细胞与遗传决定因素的研究 |
Chai, R. C. |
PDF |
N/A |
Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease |
| 脊椎动物分工的健身驱动力 |
Garcia-Ruiz, I. |
PDF |
N/A |
Fitness drivers of division of labor in vertebrates |
| 鞭毛虫鞭毛的近端部分发生了鞭毛内运输的选择性。 |
Alves, A. A. |
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N/A |
Intraflagellar Transport Selectivity Occurs with the Proximal Portion of the Trypanosome Flagellum |
| IQCG的新型微管成核因子在人类中迅速进化,具有双重作用 |
YU, H. |
PDF |
N/A |
Dual roles of IQCG, a novel microtubule nucleation factor rapidly evolving in humans |
| IQCG的新型微管成核因子的双重作用,在人类中迅速进化 |
Liu, X. |
PDF |
N/A |
Dual roles of IQCG, a novel microtubule nucleation factor rapidly evolving in humans |
| 冷凝物作为翻译枢纽,协调多核细胞的生长。 |
Geisterfer, Z. M. |
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N/A |
Condensates act as translation hubs to coordinate multinucleate cell growth |
| 对裸鼹鼠细胞中储存操纵钙进入途径的功能性表征 |
Drugachenok, P. |
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N/A |
Functional characterization of the store-operated calcium entry pathway in naked mole-rat cells |
| 果蝇依赖复制的组蛋白基因在细胞周期调控下的转录暂停 |
Kemp, J. P. |
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N/A |
Cell cycle-regulated transcriptional pausing of Drosophila replication-dependent histone genes |
| 成纤维蛋白FMNL2在黑色素瘤细胞对基质硬度的反应中起作用。 |
Clugston, J. D. |
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N/A |
The formin FMNL2 plays a role in the response of melanoma cells to substrate stiffness |
| PERK信号通过促进增殖来维持内质网应激下造血干细胞池的完整性。 |
Zheng, M. |
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N/A |
PERK Signaling Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation |
| C端HSP90二聚化小分子抑制剂通过调节自噬,并与mTOR抑制剂协同作用,杀灭顺铂耐药的癌细胞。 |
David, C. |
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N/A |
Small-molecule inhibitor of C-terminal HSP90 dimerization modulates autophagy and functions synergistically with mTOR inhibition to kill cisplatin-resistant cancer cells |
| FAF2是一种双功能调节因子,参与过氧化物酶体稳态和饱和脂质反应的调控。 |
Kim, C. |
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N/A |
FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses |
| 结果导向显微技术:细胞生物学的闭环光遗传控制 |
Passmore, J. |
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N/A |
Outcome-Driven Microscopy: Closed-Loop Optogenetic Control of Cell Biology |
| TMEM55A介导的PI5P信号通路调控α细胞肌动蛋白解聚及胰高血糖素分泌 |
Liu, X. |
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N/A |
TMEM55A-mediated PI5P signaling regulates α-cell actin depolymerization and glucagon secretion |
| 二甲双胍抑制衰老和老化过程中染色质片段的核外排 |
Kumazawa, T. |
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N/A |
Metformin inhibits nuclear egress of chromatin fragments in senescence and aging |
| 硅藻中主要转运蛋白载体亚家族的动态重定位与分化表达 |
Liu, S. |
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N/A |
Dynamic relocalization and divergent expression of a major facilitator carrier subfamily in diatoms |
| HNF4alpha在β细胞中的敲除效果是年龄和性别依赖性的。 |
Villaca, C. B. |
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N/A |
The effect of HNF4alpha knockout in beta cells is age and gender dependent |
| EMC复合体在裂殖酵母的线粒体呼吸和静止状态中起着关键作用。 |
Berraquero, M. |
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N/A |
A key role of the EMC complex for mitochondrial respiration and quiescence in fission yeasts |
| 利用氢/氘交换质谱法探究Pup连接酶PafA的结构异质性 |
Plourde, A. |
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N/A |
Probing the structural heterogeneity of Pup ligase PafA using H/D exchange mass spectrometry |
| OST组件RPN1是一种新型调控因子,能够调节IRE1的RNase活性,并与多个不同的IRE1和PERK复合体相互作用。 |
Larburu, N. |
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N/A |
OST component RPN1 is a novel regulator of IRE1 RNase activity that interacts with multiple distinct IRE1 and PERK complexes |
| 基于结构的嵌合流感血凝素设计以诱导跨组免疫 |
Castro, K. M. |
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N/A |
Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity |
| 交联介导的相互作用组分析揭示了PHD2-HIF1α相互作用热点及PHD2在调控蛋白质类泛素化中的作用 |
Ouyang, H. |
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N/A |
Crosslinking-mediated Interactome Analysis Identified PHD2-HIF1α Interaction Hotspots and the Role of PHD2 in Regulating Protein Neddylation |
| 水稻中α-扩张蛋白前体的结构表征与功能评估 |
Nayem, R. I. |
PDF |
N/A |
Structural Characterization and Functional Assessment of the Alpha-Expansin Precursor in Oryza sativa |
| 机械应力引发解剖结构变化,促进番茄提前开花,并提高产量,这一过程涉及乙烯和生长素。 |
Castro-Estrada, J. |
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N/A |
Mechanical stress induces anatomical changes, tomato early flowering, and increased yield involving ethylene and auxins |
| 探索苔藓植物小立碗藓(Marchantia polymorpha)中胞间连丝的形成与渗透性 |
Hsu, C.-Y. |
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N/A |
Exploring The Formation And Permeability Of Plasmodesmata In The Liverwort, Marchantia polymorpha |
| 普通菜豆中的非特异性磷脂酶C,PvNPC4,调控根和根瘤的发育。 |
Pacheco, R. |
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N/A |
The non-specific phospholipase C of common bean PvNPC4 modulates roots and nodule development |
| 关于Piper chaba(Chui jhal)的全面研究:植物化学成分与抗氧化作用 |
Kundu, M. |
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N/A |
A Comprehensive Study of Piper chaba (Chui jhal): Phytochemistry and Antioxidant Effects |
| 玉米自交系在昼夜转录模式上表现出等位基因变异。 |
Gage, J. L. |
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N/A |
Maize inbreds show allelic variation for diel transcription patterns |
| 观赏植物普通耧斗菜的基因组序列揭示了黄酮类生物合成基因组 |
Friedhoff, R. |
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N/A |
Genome sequence of the ornamental plant Aquilegia vulgaris reveals the flavonoid biosynthesis gene repertoire |
| 玉米粗糙胚乳6是一种预测的RNA解旋酶,对于miRNA加工和胚乳细胞模式形成是必需的。 |
Yang, T. |
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N/A |
Maize rough endosperm6 is a predicted RNA helicase required for miRNA processing and endosperm cell patterning |
| 假定的禾本科特异性EXO70类群的新功能化 |
Bergum, M. |
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N/A |
Putative neofunctionalization of a Poales-specific EXO70 clade |
| 在拟南芥中,内珠被控制胚囊发育和种子形状。 |
Mody, T. A. |
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N/A |
The inner integument controls embryo sac development and seed shape in Arabidopsis thaliana |
| 心脏成纤维细胞的细胞各向异性性由YAP依赖的细胞收缩性和细胞外基质(ECM)生成决定。 |
Pereira-Sousa, D. |
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N/A |
Cardiac fibroblasts cellular anisotropy is determined by YAP-dependent cellular contractility and ECM production |
| COMMD3在胞内体运输中的独立于指挥官的功能 |
Squiers, G. T. |
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N/A |
A Commander-independent function of COMMD3 in endosomal trafficking |
| NRBP1假激酶在渗透压应激下结合并激活WNK通路 |
Amnekar, R. |
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N/A |
NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress |
| 秀丽隐杆线虫中唯一必需的低分子量原肌球蛋白同工型对其咽肌功能至关重要。 |
Kimmich, M. J. |
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N/A |
The sole essential low molecular weight tropomyosin isoform of Caenorhabditis elegans is essential for pharyngeal muscle function. |
| 植物GORK K+通道调控中对称性转换的结构与机制洞察 |
Li, Q.-y. |
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N/A |
Structural and Mechanistic Insights into Symmetry Conversion in Plant GORK K+ Channel Regulation |
| 功能性大脑连接与音乐训练:从音乐感知中的脑电图相位同步中获得的见解 |
Provorova, A. |
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N/A |
Functional Brain Connectivity and Musical Training: Insights from EEG Phase Synchronization During Music Perception |
| 以患者来源的诱导多能干细胞为模型研究额颞叶痴呆病理 |
Barber, D. L. |
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N/A |
Patient-derived Induced Pluripotent Stem Cells as a Model to Study Frontotemporal Dementia Pathologies |
| 腹侧前运动皮层内的多稳态双峰感知编码 |
Andrade-Ortega, B. |
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N/A |
Multi-Stable Bimodal Perceptual Coding within the Ventral Premotor Cortex |
| 老龄化、阿尔茨海默病病理和APOE4对老年人纵向功能连接和情景记忆的不同影响 |
Fischer, L. |
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N/A |
Differential effects of aging, Alzheimer's pathology, and APOE4 on longitudinal functional connectivity and episodic memory in older adults |
| 多巴胺能对身份预测误差的反应依赖于眶额皮质和海马体的程度不同。 |
Takahashi, Y. |
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N/A |
Dopaminergic responses to identity prediction errors depend differently on the orbitofrontal cortex and hippocampus |
| AmpliPiper:一种多用途的扩增子测序分析工具,适用于多基因位点的DNA条形码分析 |
Bertelli, A. |
PDF |
N/A |
AmpliPiper: A versatile amplicon-seq analysis tool for multilocus DNA barcoding |
| 单细胞表示的因果解耦与可控反事实生成 |
Gao, Y. |
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N/A |
Causal disentanglement for single-cell representations and controllable counterfactual generation |
| DDI2缺乏通过恶化细胞生存条件抑制肝癌进展 |
Liu, K. |
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N/A |
Deficiency of DDI2 suppresses liver cancer progression byworsening cell survival conditions |
| 通过积极记忆回忆提升吹奏管乐器的主观表现成就:交感神经激活与情绪效价的影响 |
Watanabe, A. |
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N/A |
Enhanced Subjective Performance Achievement in Wind Instrument Playing through Positive Memory Recall: Effects of Sympathetic Activation and Emotional Valence |
| 热量限制:减轻神经元损伤的一种潜在方法:来自阿尔茨海默病细胞模型的启示 |
Sharma, A. |
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N/A |
Caloric restriction: A potential approach for mitigating neuronal damage: Lesson from cellular model of Alzheimer Disease |
| 麦哲伦企鹅在复杂的海流环境中平衡导航与觅食机会 |
Gunner, R. M. |
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N/A |
Magellanic penguins balance navigation with foraging opportunities in complex current regimes |
| mmVelo:一种用于估计跨多模态的细胞状态依赖性动力学的深度生成模型 |
Nomura, S. |
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N/A |
mmVelo: A deep generative model for estimating cell state-dependent dynamics across multiple modalities |
| 计算建模评估PKP2基因治疗对致心律失常性心肌病心室传导特性的影响 |
Ostini, A. |
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N/A |
Computational Modeling of Effects of PKP2 Gene Therapy on Ventricular Conduction Properties in Arrhythmogenic Cardiomyopathy |
| 基于脑电图的长时警觉性和注意力涣散评估:采用用户中心频率标记方法 |
Ladouce, S. |
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N/A |
EEG-based Assessment of Long-Term Vigilance and Lapses of Attention using a User-Centered Frequency-Tagging Approach |
| 脑静脉血流通过硬脑膜淋巴管调节脑液清除 |
El Kamouh, M.-R. |
PDF |
N/A |
Cerebral Venous Blood Flow Regulates Brain Fluid Clearance via Dural Lymphatics |
| 白细胞介素-1β 在心律失常性心肌病进展中起驱动作用 |
Penna, V. R. |
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N/A |
Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy |
| 一种新的Tensin1异构体促进肌动蛋白纤维组装,以实现高效的红细胞前体细胞核排出 |
Coffin, M. |
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N/A |
A novel isoform of Tensin1 promotes actin filament assembly for efficient erythroblast enucleation |
| 热选择改变了蓝贻贝幼体的遗传多样性和表现。 |
Nascimento-Schulze, J. C. |
PDF |
N/A |
Thermal selection shifts genetic diversity and performance in blue mussel juveniles |
| 非桑蚕丝素功能化提高了对齐聚吡咯-蚕丝复合材料中的电荷转移效率,以促进电刺激神经突生长 |
Borah, R. |
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N/A |
Non-mulberry silk fibroin functionalization enhances charge-transfer efficiency in aligned polypyrrole-silk composites for electrically stimulated neurite outgrowth |
| Cnot4杂合性减轻了高脂饮食引起的小鼠肥胖,并损害了PPARγ介导的脂肪细胞分化。 |
Yamaguchi, T. |
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N/A |
Cnot4 heterozygosity attenuates high fat diet-induced obesity in mice and impairs PPARγ-mediated adipocyte differentiation. |
| DKC1介导的rRNA假尿苷化通过靶向hnRNP A1来维持IRES依赖性翻译和ATF4驱动的代谢适应。 |
Gupta, A. |
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N/A |
DKC1-mediated pseudouridylation of rRNA targets hnRNP A1 to sustain IRES-dependent translation and ATF4-driven metabolic adaptation |
| B型肾插入细胞中V-ATPase相互作用蛋白Tldc2的敲除会损害尿液碱化。 |
Eaton, A. F. |
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N/A |
Knockout of the V-ATPase interacting protein Tldc2 in B-type kidney intercalated cells impairs urine alkalinization |
| 岛叶皮层编码任务对齐 |
Niediek, J. |
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N/A |
Insular cortex encodes task alignment |
| 使用深度度量学习对发育中的大脑进行功能指纹识别:一项ABCD研究 |
Xu, R. |
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N/A |
Functional fingerprinting for the developing brain using deep metric learning: an ABCD study |
| 雄性C. elegans单核神经元转录组分析揭示了性别特异性和性别共享行为的调控因子 |
Morillo, K. S. |
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N/A |
Single-Nucleus Neuronal Transcriptional Profiling of Male C. elegans Uncovers Regulators of Sex-Specific and Sex-Shared Behaviors |
| Mdivi-1对氧化低密度脂蛋白诱导的人单核细胞代谢改变、炎症反应及泡沫细胞形成的影响 |
Mosalmanzadeh, N. |
PDF |
N/A |
Modulatory Effects of Mdivi-1 on OxLDL-Induced Metabolic Alterations, Inflammatory Responses, and Foam Cell Formation in Human Monocytes |
| 计算建模揭示了胡须轻弹脑电图背后的生物学机制。 |
Tharayil, J. J. |
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N/A |
Computational modeling reveals biological mechanisms underlying the whisker-flick EEG |
| 在外部干扰后,工作记忆中重新选择视觉和运动内容时的神经动力学 |
Gresch, D. |
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N/A |
Neural dynamics of reselecting visual and motor contents in working memory after external interference |
| 自私却健忘的大脑:在低血糖期间,大脑氧代谢保持稳定,但记忆巩固受损。 |
Bose, A. |
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N/A |
The selfish yet forgetful brain: Stable cerebral oxygen metabolism during hypoglycemia but impaired memory consolidation |
| 果蝇触角中光和隐花色素对气味感觉的控制 |
Thakur, D. |
PDF |
N/A |
Control of odor sensation by light and cryptochrome in the Drosophila antenna |
| 基于机器学习的共定位与扩散分析的胰岛素类似物在细胞内的多样化运输 |
Bleshoy, S. V. |
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N/A |
Diverse Intracellular Trafficking of Insulin Analogs byMachine Learning-based Colocalization and DiffusionAnalysis |
| 预测昼夜节律调节对高血压大鼠肾脏转运蛋白的影响 |
zheng, k. |
PDF |
N/A |
Predicted Effect of Circadian Regulation of Renal Transporters in a Hypertensive Rat |
| 慢性行为和癫痫发作结果:小鼠实验性创伤性脑损伤及伴随的肺炎克雷伯菌肺部感染 |
Rewell, S. S. |
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N/A |
Chronic Behavioral and Seizure Outcomes following Experimental Traumatic Brain Injury and Comorbid Klebsiella pneumoniae Lung Infection in Mice |
| 新一代减肥药物抑制大脑奖励回路 |
Godschall, E. N. |
PDF |
N/A |
A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs |
| 针对SNAPTM-TIL的临床前概念验证:一种个性化、新一代的肿瘤浸润淋巴细胞治疗平台 |
Halder, T. G. |
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N/A |
Preclinical Proof of Concept for SNAPTM-TIL: a personalized, next-generation tumor-infiltrating lymphocyte therapy platform |
| 在觅食任务中,大黄蜂能够灵活地根据感官信息内容调整学习和决策策略。 |
Spaethe, J. |
PDF |
N/A |
Bumblebees flexibly adjust learning and decision strategies to sensory information content in a foraging task |
| 用于三维神经元培养中记录活动的应力触发型柔性微电极阵列 |
Serra, J. |
PDF |
N/A |
Stress-actuated Flexible Microelectrode Arrays for Activity Recording in 3D Neuronal Cultures |
| PepMSND:整合多层次特征工程和综合数据库以提升体内/体外肽血液稳定性预测 |
Haomeng, H. |
PDF |
N/A |
PepMSND: Integrating Multi-level Feature Engineering and Comprehensive Databases to Enhance in vivo/in vitro Peptide Blood Stability Prediction |
| 在阿尔茨海默病中使用内省变分自编码器进行多模态规范建模 |
Kumar, S. |
PDF |
N/A |
Multimodal normative modeling in Alzheimer Disease with introspective variational autoencoders |
| 纹状体的两个组成部分,即纹状小体和基质,嵌入在很大程度上不同的静息状态功能网络中。 |
Sadiq, A. |
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N/A |
The striatal compartments, striosome and matrix, are embedded in largely distinct resting state functional networks |
| 使用福尔马林固定、石蜡包埋的肿瘤样本,对基于成像的单细胞分辨率空间转录组学分析平台进行比较 |
Ozirmak Lermi, N. |
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N/A |
Comparison of imaging-based single-cell resolution spatial transcriptomics profiling platforms using formalin-fixed, paraffin-embedded tumor samples |
| 特定的SOX10增强子元件调控黑色素瘤中的表型可塑性和药物抗性 |
DeGeorgia, S. N. |
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N/A |
Specific SOX10 enhancer elements modulate phenotype plasticity and drug resistance in melanoma |
| 适应胱氨酸限制应激通过翻译上调氧化磷酸戊糖途径促进胰腺导管腺癌(PDAC)肿瘤生长和转移。 |
Li, Y. |
PDF |
N/A |
Adaptation to cystine limitation stress promotes PDAC tumor growth and metastasis through translational upregulation of OxPPP |
| 重复暴露于5G-3.5 GHz信号不会改变成年雄性小鼠的行为,但会改变其大脑内的基因表达。 |
Lameth, J. |
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N/A |
Repeated head-exposures to a 5G-3.5 GHz signal do not alter behavior but modify intracerebral gene expression in adult male mice. |
| RasGRP1信号通过调控c-Maf表达,引导发育中的γδ胸腺细胞向γδT17谱系分化。 |
Joannou, K. |
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N/A |
RasGRP1 Signalling Programs Developing γδ-Thymocytes towards the γδT17 Lineage Through Control of c-Maf Expression |
| 使用非侵入性生物监测评估未驯化的北绒毛蛛猴(Brachyteles hypoxanthus)的群体规模和人口构成 |
Kaizer, M. C. |
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N/A |
Assessing group size and the demographic composition of unhabituated northern muriqui (Brachyteles hypoxanthus) using non-invasive biomonitoring |
| 直立蛇的姿势控制 |
Hoffmann, L. A. |
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N/A |
Postural control in an upright snake |
| CCL17-CCR4轴在突变STAT6介导的复发/难治性弥漫大B细胞淋巴瘤微环境重塑和治疗抵抗中起关键作用。 |
Abraham, M. J. |
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N/A |
The CCL17-CCR4 axis is critical for mutant STAT6-mediated microenvironmental remodelling and therapeutic resistance in Relapsed/Refractory Diffuse Large B Cell Lymphoma |
| 野生大山雀离婚的时间和社会后果:一种现象学方法 |
Abraham, A. D. |
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N/A |
Timing and social consequences of divorce in wild great tits: a phenomenological approach |
| miRScore:一种快速且精确的微RNA验证工具 |
Vanek, A. |
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N/A |
miRScore: a rapid and precise microRNA validation tool |
| 针对急性髓性白血病中FBXO21介导的p85α泛素化的小分子靶向研究 |
Dobish, K. K. |
PDF |
N/A |
Small molecule targeting of FBXO21 mediated p85αubiquitylation in acute myeloid leukemia |
| Notch信号通路维持着肝细胞癌中一种类似祖细胞的亚型。 |
Seidel, K. |
PDF |
N/A |
Notch signaling maintains a progenitor-like subclass of hepatocellular carcinoma |
| 鬃毛囊地鼠(Chaetodipus hispidus)听觉脑干反应中的性别差异 |
Joseph, L. |
PDF |
N/A |
Sex Differences in Auditory Brainstem Responses in the Hispid Pocket Mouse (Chaetodipus hispidus) |
| 关注注意力:高关注度位点作为语言模型中蛋白质家族和功能的指示器 |
Nayar, G. |
PDF |
N/A |
Paying Attention to Attention: High Attention Sites as Indicators of Protein Family and Function in Language Models |
| 开始与停止 - 一个用于交互式模拟控制的PhysiCell和PhysiBoSS 2.0插件 |
Smeriglio, R. |
PDF |
N/A |
Start&Stop - a PhysiCell and PhysiBoSS 2.0 add-on for interactive simulation control |
| 感觉毛细胞中转导通道门控力的电控制。 |
Joliot, A. |
PDF |
N/A |
Electrical control of the transduction channels' gating force in sensory hair cells. |
| 整合多组学揭示前驱期和特发性帕金森病肠道微生物群功能的改变 |
Villette, R. |
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N/A |
Integrated multi-omics highlights alterations of gut microbiome functions in prodromal and idiopathic Parkinson's disease |
| 在果蝇中,繁殖和对宏量营养素的偏好与生物学年龄或时间年龄的关系不同。 |
Lushchak, O. |
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N/A |
Reproduction and preference to macronutrients have different relations to biological or chronological age in Drosophila |
| 有证据表明,听觉感知判断具有系统性——然而这种节奏性又与任务和运动相关——的节奏性。 |
Fabio, C. |
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N/A |
Evidence for systematic - yet task- and motor-contingent - rhythmicity of auditory perceptual judgements |
| MIND-Map:用于估计大脑动态状态的综合工具箱 |
Khodaei, M. |
PDF |
N/A |
MIND-Map; A Comprehensive Toolbox for Estimating Brain Dynamic States |
| 非热量甜味剂与葡萄糖共同作用影响下丘脑葡萄糖感应诱导的胰岛素分泌及通过神经细胞代谢的食物再摄取:体内与体外研究方法 |
HAYDAR, J. |
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N/A |
Non-Caloric Sweeteners combined with glucose affect hypothalamic glucose sensing-induced insulin secretion, food re-intake through neuronal cellular metabolism: An in vivo and in vitro approaches |
| 是什么使得人类皮层锥体神经元在功能上如此复杂 |
Aizenbud, I. |
PDF |
N/A |
What makes human cortical pyramidal neurons functionally complex |
| 与多发性硬化症相关的促炎分子会改变人类少突胶质细胞系细胞的发育。 |
Blaszczyk, G. J. |
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N/A |
Pro-Inflammatory Molecules Implicated in Multiple Sclerosis Divert the Development of Human Oligodendrocyte Lineage Cells |
| 肌肉协同结构和激活模式的变化是力场适应、保留和泛化的基础。 |
Herzog, M. |
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N/A |
Changes in Muscle Synergy Structure and Activation Patterns Underlie Force Field Adaptation, Retention, and Generalization |
| PinkyCaMP 是一种基于 mScarlet 的钙传感器,具有卓越的亮度、光稳定性和多重成像能力。 |
Fink, R. |
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N/A |
PinkyCaMP a mScarlet-based calcium sensor with exceptional brightness, photostability, and multiplexing capabilities |
| 在短暂缺血后,Na+/Ca2+交换器触发海马齿状细胞轴突初始段短暂性破坏。 |
Serra, C. |
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N/A |
Na+/Ca2+ exchanger triggers transient disruption of axon initial segments in hippocampal granule cells after brief ischemia. |
| 运动限制的束缚应激通过多巴胺依赖的神经可塑性抑制雄性果蝇的求偶行为。 |
Sato, T. |
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N/A |
Confinement stress with movement restriction suppresses male courtship in Drosophila through dopamine-dependent neuroplasticity |
| 基于快速有限元法的经颅磁刺激电场计算 |
Cao, F. |
PDF |
N/A |
Fast FEM-based Electric Field Calculations for Transcranial Magnetic Stimulation |
| 与年龄相关的功能平衡能力变化可预测多感官整合过程中的α波活动 |
Pepper, J. L. |
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N/A |
Age-Related Changes in Functional Balance Ability Predict Alpha Activity During Multisensory Integration |
| 一项关于优秀阅读者与不良阅读者脑电图的探索性比较研究 |
Alvarez-Alonso, M. J. |
PDF |
N/A |
An Exploratory EEG Comparison of Good and Bad Readers |
| 量化体感传入类型及其变化对疼痛敏感性的贡献:在小鼠行为过程中使用经皮光遗传学刺激 |
Xie, Y.-F. |
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N/A |
Quantifying the contribution of somatosensory afferent types and changes therein to pain sensitivity using transcutaneous optogenetic stimulation in behaving mice |
| 保持眼、头和手的协调:在连续动作任务中快速协调的视觉运动行为 |
Schroeger, A. |
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N/A |
Keeping Your Eye, Head, and Hand on the Ball: Rapidly Orchestrated Visuomotor Behavior in a Continuous Action Task |
| 青少年饮酒会以性别特异性的方式导致长期抑制反应和眶额-纹状体活动的改变。 |
McCane, A. |
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N/A |
Adolescent alcohol consumption produces long term alterations in response inhibition and orbitofrontal-striatal activity in a sex-specific manner |
| 视网膜平铺片上神经节细胞的分子与空间分析:多样性、地形分布及血管周特性 |
Tsai, N. Y. |
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N/A |
Molecular and spatial analysis of ganglion cells on retinal flatmounts: diversity, topography, and perivascularity |
| 调节腓肠肌常见突触输入和运动单位募集阈值:踝关节位置的影响 |
Yu, X. S. |
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N/A |
Modulation of Common Synaptic Inputs and Motor Unit Recruitment Threshold in TricepsSurae Muscles: Effects of Ankle Position |
| 在超急性期缺血性卒中中快速的长程突触重塑 |
Chen, H. |
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N/A |
Rapid long-range synaptic remodeling in hyperacute ischemic stroke |
| 神经元中E2F4DN的表达通过TrkB信号通路恢复了纯合5xFAD小鼠的成年神经发生。 |
Lozano-Urena, A. |
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N/A |
Neuronal expression of E2F4DN restores adult neurogenesis in homozygous 5xFAD mice via TrkB signaling |
| 球面投影对脑图自旋测试的影响 |
Bazinet, V. |
PDF |
N/A |
The effect of spherical projection on spin tests for brain maps |
| 在自然主义虚拟环境中进行自由观看时,研究与扫视启动锁定的脑电图(EEG)特征,以揭示面部感知。 |
Nolte, D. |
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N/A |
Investigating saccade-onset locked EEG signatures of face perception during free-viewing in a naturalistic virtual environment |
| 从尖峰神经网络到可解释的动力学:一个扩散近似框架 |
Mohammadi, N. |
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N/A |
From spiking neuronal networks to interpretable dynamics: a diffusion-approximation framework |
| 赖氨酸去乙酰化抑制剂逆转TDP-43的错误定位,并与阿瑞莫醇联合使用改善神经肌肉病理 |
Scozzari, S. |
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N/A |
Lysine deacetylation inhibition reverses TDP-43 mislocalization and in combination with arimoclomol ameliorates neuromuscular pathology |
| 星形胶质细胞在神经元活动中的特征:基于机器学习的识别方法 |
Pirola, J. P. |
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N/A |
Astrocytic Signatures in Neuronal Activity: A Machine Learning-Based Identification Approach |
| 个体阿尔法频率预测时间感知敏感度 |
Morrow, A. |
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N/A |
Individual Alpha Frequency Predicts the Sensitivity of Time Perception |
| 静息状态和任务状态下白质内在连接网络的证据:一项大规模研究与模板 |
Itkyal, V. S. |
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N/A |
Evidence for white matter intrinsic connectivity networks at rest and during a task: a large-scale study and templates |
| CDNF通过直接结合未折叠蛋白反应传感器PERK和IRE1α来拯救人类诱导多能干细胞衍生的多巴胺神经元。 |
Kovaleva, V. |
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N/A |
CDNF rescues human iPSCs-derived dopamine neurons through direct binding to unfolded protein response sensors PERK and IRE1α |
| 在体人类神经突交换成像(NEXI)在500 mT/m扩散梯度下 |
Chan, K.-S. |
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N/A |
In vivo human neurite exchange imaging (NEXI) at 500 mT/m diffusion gradients |
| 清醒恒河猴经颅磁刺激的皮层兴奋性评估:从募集曲线中获得的转化见解 |
Padanyi, A. |
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N/A |
Assessment of cortical excitability in awake rhesus macaques with transcranial magnetic stimulation: translational insights from recruitment curves |
| 追踪斑马鱼尾鳍肌肉的发育起源 |
Abe, G. |
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N/A |
Tracing of the developmental origin of the caudal fin muscle in zebrafish |
| 棕色变色龙(Anolis sagrei)的产卵前发育 |
Weberling, A. |
PDF |
N/A |
Pre-oviposition development of the brown anole (Anolis sagrei) |
| 自然单克隆自身抗体针对SLE患者的HERV-K102包膜-跨膜蛋白,能够选择性地消除自身反应性免疫细胞和癌细胞。 |
Gong, Q. |
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N/A |
Natural monoclonal autoantibodies against HERV-K102 Envelope-TM from SLE patients selectively eliminate autoreactive immune cells and cancer cells |
| 肌肉内脂肪组织在物理上限制了肌肉功能的恢复。 |
Norris, A. M. |
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N/A |
Intramuscular adipose tissue physically restricts functional muscle recovery |
| 一种利用流式细胞术鉴定美洲大蠊(Periplaneta americana (L.))血细胞亚群相对丰度和功能能力的方法 |
Boyer-Millander, F. J. |
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N/A |
A flow cytometric approach to identifying the relative abundance and functional capacities of hemocyte subsets in the American cockroach, Periplaneta americana (L.) |
| RNA测序揭示了男性和女性绒毛外滋养层细胞中常染色体基因表达差异的发育起始。 |
Shannon, M. J. |
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N/A |
RNA sequencing reveals the developmental onset of autosomal gene expression differences in male and female extravillous trophoblasts |
| 超长测序技术用于解析人类免疫球蛋白重链位点的连续单体型 |
Gornitzka, M. B. |
PDF |
N/A |
Ultra-long sequencing for contiguous haplotype resolution of the human immunoglobulin heavy chain locus |
| 稀有生境、稀有物种和入侵捕食者突显了科罗拉多河流域管理复杂性 |
Hossack, B. R. |
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N/A |
RARE HABITATS, RARE SPECIES, AND INVASIVE PREDATORS HIGHLIGHT MANAGEMENT COMPLEXITIES IN THE COLORADO RIVER SYSTEM |
| 森林栖息地和以森林为主的景观与具有与光敏感性相关的视觉特征的熊蜂物种有关。 |
Bartholomee, O. |
PDF |
N/A |
Forest habitat and forest dominated landscapes are associated with bumblebee species with visual traits related to light sensitivity |
| 外生菌根树木的功能性状影响其对周围土壤有机质性质的影响 |
Edwards, J. D. |
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N/A |
Functional traits of ectomycorrhizal trees influence their effects on surrounding soil organic matter properties |
| 比较转录组学揭示了在初始宿主定殖过程中,植物病原菌与内生菌之间的不同真菌策略。 |
Moonjely, S. |
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N/A |
Comparative transcriptomics reveal contrasting fungal strategies in a plant pathogen versus an endophyte during initial host colonization |
| 体外生物膜形成仅部分预测有益的荧光假单胞菌对根际病原体的保护作用。 |
Liu, Y. |
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N/A |
In vitro biofilm formation only partially predicts beneficial Pseudomonas fluorescens protection against rhizosphere pathogens |
| 野生社会性哺乳动物中主要组织相容性复合体两类的特征分析:条纹獴 |
Schubert, N. |
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N/A |
Characterization of both major histocompatibility complex classes in a wild social mammal: the banded mongoose |
| 利用PacBio技术对油橄榄(Olea europaea L. subsp. europaea)栽培品种‘Frantoio’和‘Leccino’进行基因组组装,揭示了与盐胁迫相关的关键基因在主要结构上的差异。 |
Sebastiani, L. |
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N/A |
PacBio genome assembly of Olea europaea L. subsp. europaea cultivars 'Frantoio' and 'Leccino' reveal main structural differences in key genes related to salt stress |
| 评估预训练数据集大小和多样性对单细胞基础模型性能的影响 |
DenAdel, A. |
PDF |
N/A |
Evaluating the role of pre-training dataset size and diversity on single-cell foundation model performance |
| DNA甲基化在衰老过程中的集体动态变化 |
Hashtroud, A. |
PDF |
N/A |
Collective dynamics of DNA methylation during ageing |
| 比目鱼(Scophthalmus maximus)胚胎发生的表观基因组学 |
Aramburu, O. |
PDF |
N/A |
Epigenomics of embryogenesis in turbot (Scophthalmus maximus) |
| 人口比较显示,坦噶尼喀湖丽鱼科鱼类新亮丽鲷(Neolamprologus brevis)中,更多的社会互动与更大的脑容量相关。 |
Ma, B. |
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N/A |
Population comparisons reveal more social interactions are correlated with larger brains in the Lake Tanganyikan cichlid Neolamprologus brevis |
| 描述肌萎缩侧索硬化症(ALS)的SOD1G93A小鼠模型中运动功能的性别依赖性和解剖学上的衰退 |
Shelest, O. |
PDF |
N/A |
Delineating sex-dependent and anatomic decline of motor functions in the SOD1G93A mouse model of amyotrophic lateral sclerosis |
| 物理相互作用驱动蜜蜂集体调节温度的行为 |
Lambert, C. E. |
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N/A |
Physical Interactions Drive Collective Thermoregulatory Behavior in Honey Bees |
| 光交联26S蛋白酶体基底亚复合体的重组表达 |
Yori Restrepo, S. |
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N/A |
Recombinant Expression of Photo-crosslinkable 26S Proteasome Base Subcomplex |
| 可穿戴螺旋超声贴片用于糖尿病神经性疼痛的外周神经超声调控 |
Pu, C. |
PDF |
N/A |
A Wearable Spiral Ultrasound Patch for Focused Ultrasound Peripheral Neuromodulation of Diabetic Neuropathic Pain |
| 使用锚定细胞片工程制造的肌肉特异性ECM纤维在体积性肌肉损失的大鼠模型中支持组织再生 |
Shahin-Shamsabadi, A. |
PDF |
N/A |
Muscle-Specific ECM Fibers Made with Anchored Cell Sheet Engineering Support Tissue Regeneration in Rat Models of Volumetric Muscle Loss |
| 通过从人类细胞图谱推断基因网络来增强人类相互作用组,以进行疾病预测 |
Sung, E. |
PDF |
N/A |
Augmenting the human interactome for disease prediction through gene networks inferred from human cell atlas |
| 高维中介分析以阐明代谢物在PFAS暴露与妊娠期SARS-CoV-2 IgG减少之间的关联中的作用 |
Guan, H. |
PDF |
N/A |
High-dimensional mediation analysis to elucidate the role of metabolites in the association between PFAS exposure and reduced SARS-CoV-2 IgG in pregnancy |
| 基于空间多组学的鼠标前脑区域特异性分子特征及胆碱能神经元亚型分类的综合分析 |
Chen, Y. |
PDF |
N/A |
Mouse Forebrain Region-specific Molecular Characteristics and Cholinergic Neurons Subtyping: An Integrated Analysis Based on Spatial Multi-omics |
| scMusketeers: 通过模块化自动编码器解决细胞类型注释不平衡和批次效应减少问题 |
Collin, A. |
PDF |
N/A |
scMusketeers: Addressing imbalanced cell type annotation and batch effect reduction with a modular autoencoder |
| 通过单细胞转录组学、整体转录组学和实验验证揭示的1型糖尿病免疫机制 |
Gao, W. |
PDF |
N/A |
Immune mechanisms of type 1 diabetes revealed by single-cell transcriptomics, bulk transcriptomics, and experimental validation |
| Plasmo3Net:一种基于卷积神经网络的算法,用于检测薄血涂片图像中的疟原虫 |
Owoloye, A. |
PDF |
N/A |
Plasmo3Net: A Convolutional Neural Network-Based Algorithm for Detecting Malaria Parasites in Thin Blood Smear Images |
| 一个针对影响动物种群的新发传染病的实时预测框架 |
Theng, M. |
PDF |
N/A |
A real-time forecasting framework for emerging infectious diseases affecting animal populations |
| 量化DIA-MS数据集中之前未被量化的约75-95%的肽段 |
Saxena, G. |
PDF |
N/A |
Quantifying the ~75-95% of Peptides in DIA-MS Datasets that were not Previously Quantified |
| Echidna:一种用于量化影响表型可塑性的基因剂量效应的贝叶斯框架 |
Fan, J. L. |
PDF |
N/A |
Echidna: A Bayesian framework for quantifying gene dosage effect impacting phenotypic plasticity |
| 利用荧光共振能量转移(FRET)在工程化黄色和青色蛋白之间进行淀粉样纤维的定量检测 |
Moustouka, C. |
PDF |
N/A |
Quantitative Detection of Amyloid Fibrils using Fluorescence Resonance Energy Transfer (FRET) Between Engineered Yellow and Cyan Proteins |
| 使用分子动力学模拟解码温度对未结合配体的温度感应腺嘌呤核开关的构象稳定性和有序性的影响 |
Das, S. |
PDF |
N/A |
Decoding the effect of temperatures on conformational stability and order of the ligand unbound thermo-sensing adenine riboswitch using molecular dynamics simulation |
| 使用原子模拟深入研究α-突触核蛋白P1结构域的热响应相行为 |
Chakraborty, S. |
PDF |
N/A |
Insight into the Thermo-responsive Phase Behavior of P1 Domain of α-synuclein using Atomistic Simulations |
| 关于巴西东部拉戈阿圣塔中全新世时期一种小型食果蝙蝠的注记 |
Chahud, A. |
PDF |
N/A |
NOTE ON A SMALL FRUIT-EATING BAT FROM THE MIDDLE HOLOCENE OF LAGOA SANTA, EASTERN BRAZIL |
| CoREST复合物抑制剂corin能够减少非典型畸胎瘤横纹肌样瘤异种移植模型中的肿瘤生长,促进细胞分化,并延长寿命。 |
Geethadevi, A. |
PDF |
N/A |
The CoREST complex inhibitor, corin, leads to decreased tumor growth, increased cellular differentiation and extended lifespan in atypical teratoid rhabdoid tumor xenograft models |
| 拟除虫菊酯类杀虫剂溴氰菊酯会干扰胃肠道中的神经肽和单胺信号传导通路。 |
White, A. C. |
PDF |
N/A |
The pyrethroid insecticide deltamethrin disrupts neuropeptide and monoamine signaling pathways in the gastrointestinal tract |
| 一个三维体外模型再现了体内特征,并揭示了儿童急性淋巴细胞白血病中药物耐受性增加的现象。 |
Kanari, M. |
PDF |
N/A |
A three-dimensional ex vivo model recapitulates in vivo features and unravels increased drug resistance in childhood acute lymphoblastic leukemia |
| 评估了氧化锌纳米颗粒介导的Aframomum citratum(C. Pereira)K. Schum(姜科)在Wistar大鼠中的抗炎作用 |
Eya'ane Meva, F. |
PDF |
N/A |
Anti-inflammatory assessment of zinc oxide nanoparticles mediated Aframomum citratum (C. Pereira) K. Schum (Zingiberaceae) in Wistar rats |
| PRMT1介导的代谢重编程促进白血病发生 |
Su, H. |
PDF |
N/A |
PRMT1-Mediated Metabolic Reprogramming Promotes Leukemogenesis |
| CRISPR-Cas9 RALA敲除与重建。RALA S194磷酸化在RAS依赖性和RAS非依赖性癌症中的检测与作用。 |
Konde, M. |
PDF |
N/A |
CRISPR-Cas9 RALA knockout and reconstitution. Detection and role of RALA S194 phosphorylation in RAS-dependent and RAS-independent cancers. |
| 高通量靶向药物筛选用于治疗NF1相关的高级别胶质瘤,这些肿瘤存在ATRX缺陷 |
Dubey, S. |
PDF |
N/A |
High-Throughput Targeted Drug Screening for NF1-associated High-Grade Gliomas with ATRX Deficiency |
| G蛋白失活作为成瘾治疗的一种机制 |
Neiswanger, C. |
PDF |
N/A |
G protein Inactivation as a Mechanism for Addiction Treatment |
| 果蝇视叶中的差异时间滤波 |
Borst, A. |
PDF |
N/A |
Differential temporal filtering in the fly optic lobe |
| 在意识状态改变期间,楔前叶的功能梯度减弱 |
Lyu, D. |
PDF |
N/A |
Diminished functional gradient of the precuneus during altered states of consciousness |
| 在阿尔茨海默病小鼠模型中,海马区过度表达肌肉因子Irisin的行为和代谢效应 |
Borukhin, J. A. |
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N/A |
Behavioral and metabolic effects of extended hippocampal overexpression of the myokine Irisin in an Alzheimers Disease mouse model |
| 通过皮质和周围躯体感觉刺激调节运动皮质可塑性 |
Bao, S. |
PDF |
N/A |
Modulating Motor Cortex Plasticity via Cortical and Peripheral Somatosensory Stimulation |
| 锥体细胞和中间神经元在尖波纹波的作用下被强烈地重新激活。 |
Javed, M. H. |
PDF |
N/A |
cfos principal cells and interneurons are strongly reactivated by sharp wave ripples |
| 瞬时频率:动态脑因果网络的新型功能生物标志物 |
Tang, H. |
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N/A |
Instantaneous Frequency: A New Functional Biomarker for Dynamic Brain Causal Networks |
| AOSLO光栅扫描视觉刺激对视网膜ON和OFF通路的非对称激活 |
Patterson, S. S. |
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N/A |
Asymmetric Activation of Retinal ON and OFF Pathways by AOSLO Raster-Scanned Visual Stimuli |
| 时间分辨的睡眠阶段神经振荡:与睡眠质量和衰老的关联 |
Passaro, A. D. |
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N/A |
Time-Resolved Neural Oscillations Across Sleep Stages: Associations with Sleep Quality and Aging |
| 伏隔核核心中的A2A阳性神经元调节努力程度 |
Shoemaker, C. T. |
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N/A |
A2A-positive neurons in the nucleus accumbens core regulate effort exertion |
| 使用预训练的编码器-解码器框架,从直接皮质记录中进行自然语音的重新合成 |
Li, J. |
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N/A |
Natural speech re-synthesis from direct cortical recordings using a pre-trained encoder-decoder framework |
| 慢性背痛小鼠模型的神经免疫机制 |
Goins, A. E. |
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N/A |
Neuroimmune mechanisms of a mouse model of chronic back pain |
| 考虑到更复杂的囊泡池模型,对量子突触参数的估计 |
Bornschein, G. |
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N/A |
Estimates of quantal synaptic parameters in light of more complex vesicle pool models |
| 同步三维模式化多种中枢神经系统祖细胞生成具有广泛轴向特征的运动神经元 |
Buchner, F. |
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N/A |
Synchronous 3D patterning of diverse CNS progenitors generates motor neurons of broad axial identity |
| 在人类视觉工作记忆中,区分θ和α振荡与非周期性神经活动的贡献 |
van Engen, Q. |
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N/A |
Dissociating Contributions of Theta and Alpha Oscillations from Aperiodic Neural Activity in Human Visual Working Memory |
| 通过背景去除的单光子钙成像连续预测小鼠压杆运动学参数 |
Li, M. |
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N/A |
Continuous Prediction of Mice Lever-Pressing Kinematic Parameters by Background Removed Single-photon Calcium Images |
| 糖尿病对结核病病理生理学的影响:AGE-RAGE轴和糖化蛋白的作用 |
Panda, S. |
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N/A |
Implications of diabetes mellitus on pathophysiology of Tuberculosis: Role of AGE-RAGE Axis and Glycated Proteins |
| 脓毒症引起人类造血干细胞/祖细胞(HSPCs)的长期重编程,并驱动脓毒症幸存者的髓系失调。 |
De Zuani, M. |
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N/A |
Sepsis induces long-term reprogramming of human HSPCs and drives myeloid dysregulation in sepsis survivors |
| 基于巨大芽孢杆菌(Priestia megaterium)ILBB592的生物肥料提高了磷肥的施用效率,积极影响大豆的营养和产量,并改变了根际细菌群落。 |
Torres, P. |
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N/A |
Priestia megaterium ILBB592 based biofertilizer increases the efficiency of phosphorus fertilization, positively affects soybean nutrition and yield and modifies the rhizospheric bacterial community |
| 一种细菌NLR相关蛋白能够识别多种不相关的噬菌体触发因素,以感知感染。 |
Kibby, E. M. |
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N/A |
A bacterial NLR-related protein recognizes multiple unrelated phage triggers to sense infection |
| 野生狒狒肠道微生物群中真核生物在不同季节和社会群体间的组成 |
Chege, M. |
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N/A |
Eukaryotic composition across seasons and social groups in the gut microbiota of wild baboons |
| 狂犬病糖蛋白的深度突变扫描确定了突变约束和抗体逃逸突变 |
Aditham, A. K. |
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N/A |
Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations |
| METTL7A通过减轻氧化应激来提高牛体细胞核移植胚胎的发育能力 |
Zhu, L. |
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N/A |
METTL7A improves bovine IVF embryo competence by attenuating oxidative stress |
| 斑马鱼中的原肠胚形成需要由NADPH氧化酶产生的活性氧物种来调节囊泡运输。 |
Ramirez Corona, A. |
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N/A |
Epiboly in zebrafish requires reactive oxygen species produced by NADPH oxidases for the regulation of vesicular trafficking |
| 海星Patiria miniata培养技术的进展 |
Barone, V. |
PDF |
N/A |
Advances in culturing of the sea star Patiria miniata |
| 使用人源类躯干结构(hTLS)模拟体节与神经管之间的共同发育 |
Makwana, K. |
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N/A |
Modelling co-development between somites and neural tube with human Trunk-like Structures (hTLS) |
| 降水耐受性决定了印度西高止山脉留鸟的垂直迁移策略。 |
Akshay, V. A. |
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N/A |
Precipitation tolerance determines elevational migration strategies of resident birds of the Western Ghats of India. |
| Gloger法则如何预测鸟类对近红外和中红外辐射的吸收? |
Lee, T. |
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N/A |
How does Gloger's rule predict near- and mid-infrared radiation in birds? |
| 利用环境DNA(eDNA)探索食果性相互作用:以木瓜(Carica papaya)和菠萝(Ananas comosus)为例 |
Banerjee, P. |
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N/A |
Harnessing Environmental DNA (eDNA) to Explore Frugivorous Interactions: A Case Study in Papaya (Carica papaya) and Pineapple (Ananas comosus) |
| 广泛遗传检测控制猫遗传性多囊肾病 |
Ukawa, H. |
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N/A |
Widespread genetic testing control inherited polycystic kidney disease in cats |
| 由LINE-1逆转录转座子引起的染色体重排和不稳定性 |
Mendez-Dorantes, C. |
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N/A |
Chromosomal rearrangements and instability caused by the LINE-1 retrotransposon |
| 用于早期检测猫退行性关节疾病的加速度计衍生分类器 |
Montout, A. |
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N/A |
Accelerometer-derived classifiers for early detection of degenerative joint disease in cats |
| 物质的重要性:原材料影响着僧帽猴的石器工具性能 |
O'Malley, T. D. R. |
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N/A |
Material matters: raw material influences stone tool performance in capuchin monkeys |
| 蚂蚁根据过去、即将来临和预测的逆境进行适应性决策 |
Notomi, Y. |
PDF |
N/A |
Adaptive decision-making by ants in response to past, imminent, and predicted adversity |
| Dairy DigiD ~ 一种基于深度学习的非侵入式生物识别系统,利用Detectron2技术对奶牛进行身份识别 |
Mahato, S. |
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N/A |
Dairy DigiD ~ A Deep Learning-Based, Non-Invasive Biometric Identification System for Dairy Cattle Using Detectron2 |
| StayRose:一种通过遗传密码扩展实现红移的光稳定StayGold衍生物 |
Scott, W. |
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N/A |
StayRose: a photostable StayGold derivative red-shifted by genetic code expansion |
| 解析复杂遗传模式特征:从基因面板的角度 |
Szyda, J. |
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N/A |
Unravelling traits with complex inheritance mode: a gene panel perspective |
| 在存在拷贝数变异、非整倍体和多倍体生物的情况下进行短串联重复序列的基因分型 |
Verbiest, M. A. |
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N/A |
Genotyping Short Tandem Repeats Across Copy Number Alterations, Aneuploidies, and Polyploid Organisms |
| dsRNAmax:一种用于安全有效作物保护的多靶点嵌合dsRNA设计工具 |
Fletcher, S. J. |
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N/A |
dsRNAmax: a Multi-Target Chimeric dsRNA Designer for Safe And Effective Crop Protection |
| 有机磷化合物的计算机毒性评估:基于密度泛函理论和分子对接研究其与人体血清白蛋白(HSA)的相互作用 |
Singh, T. |
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N/A |
In Silico Toxicity Assessment of Organophosphates: A DFT and Molecular Docking Study on Their Interaction with Human Serum Albumin (HSA) |
| 发现通路蛋白折叠中间体揭示了折叠与错误折叠之间的动力学竞争 |
Luan, Q. |
PDF |
N/A |
Discovery of an on-pathway protein folding intermediate illuminates the kinetic competition between folding and misfolding |
| 机械力调节PD-1的抑制功能 |
Chen, H. |
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N/A |
Mechanical force regulates the inhibitory function of PD-1 |
| 通过3D葡聚糖水凝胶培养调节细胞变形性以调控小鼠脾脏和肝脏中间充质干细胞的微循环 |
Zhu, X. |
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N/A |
Modulating Cellular Deformability via 3D Dextran Hydrogel Cultivation to Regulate the Microcirculation of Mesenchymal Stem Cells in Murine Spleen and Liver |
| 嗜酸性粒细胞通过抑制促肿瘤的SPP1+巨噬细胞分化来限制结直肠癌的转移。 |
Handler, K. |
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N/A |
Eosinophils restrict CRC metastasis by inhibiting pro-tumorigenic SPP1+ macrophage differentiation |
| 利用组织病理学图像进行结直肠癌亚型分类的深度学习驱动个性化医疗 |
Truong Le, T. |
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N/A |
Deep Learning-Driven Subtype Classification of Colorectal Cancer Using Histopathology Images for Personalized Medicine |
| 优化用于福尔马林固定人组织中肠神经系统免疫组织化学评估的实验方案。 |
Hong, S. M. |
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N/A |
Optimization of protocols for immunohistochemical assessment of enteric nervous system in formalin fixed human tissue. |
| NRBP1和TSC22D蛋白通过调节WNK通路,影响远端卷曲小管的生理功能。 |
Magana-Avila, G. R. |
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N/A |
NRBP1 and TSC22D proteins impact distal convoluted tubule physiology through modulation of the WNK pathway |
| 肝细胞肉毒碱棕榈酰转移酶1a的失活降低了小鼠中含载脂蛋白B的脂蛋白水平。 |
Helsley, R. N. |
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N/A |
Hepatic Inactivation of Carnitine Palmitoyltransferase 1a Lowers Apolipoprotein B Containing Lipoproteins in Mice |
| 基于动力学模型的多株酿酒酵母菌株工程改造提高了对香豆酸的生产 |
Narayanan, B. |
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N/A |
Kinetic-model-guided engineering of multiple S. cerevisiae strains improves p-coumaric acid production |
| 在山区生存:温度和海拔对喜马拉雅山脉中的悬停蝇(Eristalis tenax)具有相反的生理影响。 |
Gharpure, G. |
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N/A |
Surviving in the mountains: Temperature and elevation have contrasting physiological effects on the hoverfly Eristalis tenax in the Himalayas |
| 控制资源弹性 |
Solomyak, L. |
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N/A |
The resource elasticity of control |
| 大脑图谱显示了整体认知功能及其与神经生物学皮质特征的空间相关性 |
Moodie, J. E. |
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N/A |
Brain maps of general cognitive function and spatial correlations with neurobiological cortical profiles |
| 周围神经的生理活动影响神经对外加电刺激的输出反应:一项体内研究 |
Madden, L. R. |
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N/A |
Physiological activity within peripheral nerves influences neural output in response to electrical stimulation: an in vivo study |
| 中央脑网络在梳理过程中支撑身体部位的协调 |
Ozdil, P. G. |
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N/A |
Centralized brain networks underlie body part coordination during grooming |
| 成像跳舞的大脑:在双人舞蹈中解码感觉、运动和社会过程 |
Bigand, F. |
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N/A |
Imaging the dancing brain: Decoding sensory, motor and social processes during dyadic dance |
| 整合多系统环境因素以预测青少年大脑与行为 |
Ramduny, J. |
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N/A |
Integrating multi-system environmental factors to predict brain and behavior in adolescents |
| 视觉和前庭系统对垂直运动的处理:一项心理物理学研究 |
Delle Monache, S. |
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N/A |
Visual and vestibular processing of vertical motion: a psychophysical study |
| 一种基于低成本FPGA的用于校正堆叠的高速活体FLIM成像方法 |
Moros, F. V. |
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N/A |
A low-cost FPGA-based approach for pile-up corrected high-speed in vivo FLIM imaging |
| 裸盖菇素会导致大脑信号传导通路发生与性别、时间和剂量相关的改变。 |
Barnett, J. H. |
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N/A |
Psilocybin causes sex, time, and dose dependent alterations in brain signaling pathways |
| 导水管周围灰质超越失望,传递出对剩余奖励预期的持续信号。 |
Lee, H. |
PDF |
N/A |
Periaqueductal gray passes over disappointment and signals continuity of remaining reward expectancy |
| 减少的肠道BDNF-TrkB信号传导驱动糖皮质激素介导的胃肠动力障碍 |
Slosberg, J. S. |
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N/A |
Reduced enteric BDNF-TrkB signaling drives glucocorticoid-mediated GI dysmotility |
| 光遗传学抑制消除了感觉输入在大脑皮层的整合 |
Ambrosone, M. |
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N/A |
Optogenetic inhibition quenches the integration of sensory input in the cortex |
| Wdr45基因突变导致早期运动功能障碍和广泛异常的轴突终末,这一现象在基于β-螺旋桨蛋白相关神经退行性疾病(BPAN)患者特征的小鼠模型中得到体现。 |
Meyerink, B. L. |
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N/A |
Mutation in Wdr45 leads to early motor dysfunction and widespread aberrant axon terminals in a beta-propeller protein associated neurodegeneration (BPAN) patient-inspired mouse model |
| 荧光寿命成像揭示了神经元中α-突触核蛋白种子聚集的机制 |
Ivey, P.-M. E. |
PDF |
N/A |
Mechanisms of Alpha-Synuclein Seeded Aggregation in Neurons Revealed by Fluorescence Lifetime Imaging |
| 二态神经网络结构使雄性C.elegans优先进行与性相关的行为 |
WANG, X. |
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N/A |
Dimorphic Neural Network Architecture Prioritizes Sexual-related Behaviors in Male C.elegans |
| 弗朗西斯菌新凶手菌(Francisella novicida)形成外膜管的过程涉及广泛的细胞膜修饰,并与VI型分泌系统的活动以及宿主吞噬体膜的改变密切相关。 |
Rashid, M. |
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N/A |
Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and is linked with type VI secretion and alterations to the host phagosomal membrane |
| 抗生素对Oct-TriA1的从头进化抗性 |
Chowdhury, F. R. |
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N/A |
De novo evolution of antibiotic resistance to Oct-TriA1 |
| 一个完整的胶原蛋白IV荧光素敲入工具包揭示了基底膜中的-链多样性 |
Srinivasan, S. |
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N/A |
A complete collagen IV fluorophore knock-in toolkit reveals -chain diversity in basement membrane |
| 早期秀丽隐杆线虫胚胎中新蛋白质翻译的景观与调控 |
Shukla, Y. |
PDF |
N/A |
Landscape and regulation of new protein translation in the early C. elegans embryo |
| 牛胚外内胚层细胞的建立 |
Ming, H. |
PDF |
N/A |
Establishment of bovine extraembryonic endoderm cells |
| 温暖或明亮 - 昆虫传粉者在微生境中对温度和光照的利用 |
Bartholomee, O. |
PDF |
N/A |
Warm or bright - temperature and light microhabitat use in insect pollinators |
| 微孢子虫寄生虫利用宿主的机制 |
Silva, L. M. |
PDF |
N/A |
Mechanisms of host exploitation by a microsporidian parasite |
| 量子介导的细菌信号传导能否解释适应性突变? |
Ross, P. |
PDF |
N/A |
Could Quantum-Mediated Bacterial Signaling Explain Adaptive Mutation? |
| 衰老会破坏卵巢周期中的时空协调性。 |
Lan, T. C. T. |
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N/A |
Aging disrupts spatiotemporal coordination in the cycling ovary |
| 染色体外DNA介导的谷氨酰胺合成酶2(GS2)扩增使苋菜(Amaranthus palmeri)获得草铵膦抗性。 |
Noguera, M. M. |
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N/A |
Extrachromosomal DNA-mediated glutamine synthetase 2 (GS2) amplification enables glufosinate resistance in Amaranthus palmeri |
| 亚聚类、标记识别以及植物单细胞RNA-seq数据分析中受原生质体化影响的多组学整合 |
Yao, J. |
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N/A |
Sub-clustering, marker identification and multi-omics integration influenced by protoplasting in plant scRNA -seq data analysis |
| SurFlex显微镜:测量表面结合生物分子的柔性 |
Chorlay, A. |
PDF |
N/A |
SurFlex Microscopy: Measuring Flexibility of Surface-Tethered Biomolecules |
| FLASH放疗与常规剂量率放疗在同种异体小鼠乳腺癌模型中的疗效比较 |
Melemenidis, S. |
PDF |
N/A |
Effectiveness of FLASH vs conventional dose rate radiotherapy in a model of orthotopic, murine breast cancer |
| 一种新型泛I类葡萄糖转运蛋白抑制剂DRB18在体外和体内与紫杉醇联合使用对人非小细胞肺癌表现出协同效应。 |
Shriwas, P. |
PDF |
N/A |
A novel pan class-I glucose transporter inhibitor DRB18 exhibits synergistic effects in vitro and in vivo with paclitaxel against human non-small cell lung cancer |
| MCM2通过促进促血管生成的cardiosome信号传导,介导了心肌梗死后心脏保护作用。 |
Alam, P. |
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N/A |
MCM2 mediates post-MI cardioprotection by promoting the pro-angiogenic cardiosome signaling |
| 蛋白质组学分析揭示了在表达PINTAC肽的帕金森病表型毒素模型中,PERK/ISR与MAPK1在翻译控制中的复杂相互作用。 |
NALLUR, G. N. |
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N/A |
Proteomic analysis reveals complex interactions between PERK/ISR and MAPK1 in translational control in a phenotypic toxin model of Parkinsons disease expressing PINTAC peptides. |
| 运动皮层和纹状体中神经动力学层次结构在自然行为中的表现 |
Xing, D. Y. |
PDF |
N/A |
Neural dynamics hierarchy in motor cortex and striatum across naturalistic behaviors |
| 我该去哪里?利用卷积神经网络解码场景处理与视觉空间记忆交互的时间神经动态 |
Naveilhan, C. |
PDF |
N/A |
Where do I go? Decoding temporal neural dynamics of scene processing and visuospatial memory interactions using CNNs |
| 脑微观结构的寿命规范建模 |
Reina, J. E. V. |
PDF |
N/A |
Lifespan Normative Modeling of Brain Microstructure |
| 海草相关炭疽菌(Colletotrichum sp.)的基因组简化可能与其适应海洋单子叶植物宿主有关。 |
Ettinger, C. L. |
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N/A |
Genomic streamlining of seagrass-associated Colletotrichum sp. may be related to its adaptation to a marine monocot host |
| 在病例对照全基因组关联研究中,r2的数学界限及效应大小的影响 |
Paye, S. M. |
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N/A |
Mathematical bounds on r2 and the effect size in case-control genome-wide association studies |
| 探索罕见变异间的基因相互作用揭示了易受复杂疾病影响的基因网络 |
Jiang, H. |
PDF |
N/A |
Exploring Genetic Interactions with Rare Variants Reveals Gene Networks Susceptible to Complex Diseases |