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BioRxiv 2024-12-24 Papers

标题 作者 PDF链接 代码仓库 Title
自然选择塑造了鸟类和哺乳动物的种群动态。 Witting, L. PDF N/A Natural selection shapes the population dynamics of birds and mammals
由疾病相关突变揭示的小热休克蛋白HSPB5的激活机制。 Woods, C. N. PDF N/A Activation mechanism of Small Heat Shock Protein HSPB5 revealed by disease-associated mutants.
营养卵影响蚂蚁Pogonomyrmex rugosus的种姓决定 Genzoni, E. PDF N/A Trophic eggs affect caste determination in the ant Pogonomyrmex rugosus
脂质双层增强膜蛋白的协作网络 Muhammednazaar, S. PDF N/A Lipid Bilayer Strengthens the Cooperative Network of Membrane Proteins
常见变异对人类大脑基因表达的影响:从RNA到蛋白质再到精神分裂症风险 Liang, Q. PDF N/A The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk
狼鳍鱼化石中的古DNA:进化关键发现与方法论再评估 Zhao, W. PDF N/A Ancient DNA in Lycoptera Fossils: Key Discoveries for Evolution and Methodological Reassessment
通过前馈-循环回路的对齐,连贯的皮层表征在经验后得以发展。 Lempel, A. A. PDF N/A Coherent cortical representations develop after experience via feedforward-recurrent circuit alignment
对侧海马扩散性去极化促进卒中后功能恢复 Boyce, A. K. PDF N/A Contralesional hippocampal spreading depolarization promotes functional recovery after stroke
Spotiflow:基于深度立体流回归的荧光显微镜精确高效斑点检测

解释: - "Spotiflow" 是工具或方法的名称,保留不变。 - "accurate and efficient" 翻译为“精确高效”,强调方法的准确性和效率。 - "spot detection" 翻译为“斑点检测”,指的是在图像中识别和定位斑点的过程。 - "fluorescence microscopy" 翻译为“荧光显微镜”,指的是使用荧光技术进行显微观察的方法。 - "deep stereographic flow regression" 翻译为“深度立体流回归”,指的是使用深度学习技术进行立体流回归分析的方法。

整体翻译传达了原文的核心内容,同时保持了专业术语的准确性。 | Mantes, A. D. | PDF | N/A | Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression | | 阿片类药物诱导的风险行为在前边缘前额叶皮层的神经特征 | Quave, C. B. | PDF | N/A | Neural signatures of opioid-induced risk-taking behavior in the prelimbic prefrontal cortex | | 相同句子,不同语法,不同大脑反应:一项关于印地语和尼泊尔语分裂作格结构中格与一致性编码的脑磁图研究 | Chacon, D. A. | PDF | N/A | Same Sentences, Different Grammars, Different Brain Responses: An MEG study on Case and Agreement Encoding in Hindi and Nepali Split-Ergative Structures | | 纹状体动作选择与强化学习的动态机制 | Lindsey, J. | PDF | N/A | Dynamics of striatal action selection and reinforcement learning | | 结合无线电遥测和雷达测量技术,测试一种空中食虫鸟类的优化觅食行为 | Bloch, I. | PDF | N/A | Combining radio-telemetry and radar measurements to test optimal foraging in an aerial insectivore bird | | 通过外部切趾相位对比显微镜对活体哺乳动物细胞内的结构进行无标记成像 | Ohno, H. | PDF | N/A | Label-free imaging of intracellular structures in living mammalian cells via external apodization phase-contrast microscopy | | 根瘤菌效应因子NopT靶向结瘤因子受体以调控百脉根中的共生关系 | Bao, H. | PDF | N/A | The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus | | Kv2.2通道介导前列腺素E2对胰腺β细胞中葡萄糖刺激的胰岛素分泌的抑制作用。 | Pan, C. | PDF | N/A | The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells | | 阈下经颅磁刺激对桡侧腕屈肌长潜伏期反应的抑制作用 | Helm, C. A. | PDF | N/A | Inhibitory Effect of Subthreshold TMS on the Long-latency Response in the Flexor Carpi Radialis | | 细胞外囊泡主要通过整合素和GM1与层粘连蛋白的相互作用粘附在细胞上。 | Isogai, T. | PDF | N/A | Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin | | 肠道胶质细胞调控潘氏细胞分泌及肠道微生物生态 | Prochera, A. | PDF | N/A | Enteric glia regulate Paneth cell secretion and intestinal microbial ecology | | 食品添加剂二氧化钛对免疫活性细胞的靶向作用 | Wills, J. W. | PDF | N/A | Immunocompetent Cell Targeting by Food-Additive Titanium Dioxide | | 需要一个由δ-微管蛋白/ε-微管蛋白/Ted蛋白组成的复合物来维持中心粒的结构。 | Pudlowski, R. | PDF | N/A | A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture | | 拯救DNMT1未能完全逆转其在小鼠胚胎干细胞中缺失的分子和功能影响 | Elder, E. | PDF | N/A | Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells | | 由GABA能、谷氨酸能和章鱼胺能神经元介导的非自主性UPRER的独特机制。 | Coakley, A. J. | PDF | N/A | Distinct mechanisms of non-autonomous UPRER mediated by GABAergic, glutamatergic, and octopaminergic neurons. | | 端到端神经网络的挑战性冷冻电镜和冷冻电子断层扫描数据集从头重建 | Levy, A. | PDF | N/A | End-to-end neural ab initio reconstruction of challenging cryo-EM and cryo-ET datasets | | 多种毒素展现出与烟碱型乙酰胆碱受体的共同结合模式,揭示了一种新的分子决定因素。 | Do, H. N. | PDF | N/A | Diverse toxins exhibit a common binding mode to the Nicotinic Acetylcholine Receptors revealing a new molecular determinant | | 水禽的延迟二色性作为评估生命率的便捷工具 | Tableau, A. | PDF | N/A | Delayed dichromatism in waterfowl as a convenient tool for assessing vital rates | | 多巴胺能够增加海马神经元的蛋白质合成,从而促进多巴胺依赖的长时程增强(LTP)。 | Fuchsberger, T. | PDF | N/A | Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTP | | 尽管存在竞争,但仍能共存:植被结构复杂性对演替过程中苔藓植物多样性的影响。 | Hanusch, M. | PDF | N/A | Coexistence despite competition: Effects of vegetation structural complexity on bryophyte diversity over succession. | | 生态进化引导的病理组学分析用于预测导管原位癌升级 | Xiao, Y. | PDF | N/A | Eco-evolutionary Guided Pathomic Analysis to Predict DCIS Upstaging | | 揭示纳木错湖中隐藏的RNA病毒多样性:来自极端高海拔环境的进化洞见 | Wu, L. | PDF | N/A | Uncovering the hidden RNA virus diversity in Lake Nam Co: evolutionary insights from an extreme high-altitude environment | | 淀粉样变性轻链的构象指纹。 | Paissoni, C. | PDF | N/A | A conformational fingerprint for amyloidogenic light chains. | | T3SS转位子通过直接与NLRC4/NAIP炎症小体相互作用诱导细胞焦亡。 | Zhao, Y. | PDF | N/A | T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome | | 在基于长梯度折射率(GRIN)透镜的显微内窥镜中进行像差校正,以实现深部脑区域的扩展视野双光子成像 | Sattin, A. | PDF | N/A | Aberration correction in long GRIN lens-based microendoscopes for extended field-of-view two-photon imaging in deep brain regions | | 节丛孢菌(Arthrobotrys oligospora)的线虫捕捉装置是一种适应温度变化的铁储存表型

翻译说明: - Nematode-Trapping Devices:线虫捕捉装置,指的是节丛孢菌用于捕捉线虫的特殊结构。 - Arthrobotrys oligospora:节丛孢菌,是一种能够捕捉线虫的真菌。 - Iron Storage Phenotype:铁储存表型,指该真菌在特定条件下表现出储存铁的特性。 - Adapted to Temperature Changes:适应温度变化,表明这种表型能够随着温度的变化而调整。

整句话的意思是,节丛孢菌的线虫捕捉装置具有储存铁的特性,这种特性使其能够适应温度的变化。 | Zhou, J. | PDF | N/A | Nematode-Trapping Devices of Arthrobotrys oligospora is an Iron Storage Phenotype Adapted to Temperature Changes | | 野生狒狒肠道微生物组年龄的社会和环境预测因素 | Dasari, M. R. | PDF | N/A | Social and environmental predictors of gut microbiome age in wild baboons | | 单细胞整合与多模态分析揭示了结直肠癌中中性粒细胞的表型及空间组织特征。 | Marteau, V. | PDF | N/A | Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer | | 神经突扩散标志物的发育变化在海马体的不同区域表现出差异,并且与海马组织的细胞组成共同变化。 | Kember, J. | PDF | N/A | Developmental changes in diffusion markers of neurite vary across the hippocampus and covary with the cellular composition of hippocampal tissue | | 选择性血清素再摄取抑制剂(SSRIs)对中缝背核血清素神经元空间转录组的影响 | Henningson, C. | PDF | N/A | Effects of SSRIs on the spatial transcriptome of dorsal raphe serotonin neurons | | P3定点突变:一种基于带有3'突出端的引物对的高效方法 | Mousavi, N. | PDF | N/A | P3 site-directed mutagenesis: An efficient method based on primer pairs with 3' overhangs | | p-ClustVal:一种新颖的p-adic方法,用于增强高维度单细胞RNA测序数据的聚类分析

这段翻译将“p-ClustVal”保留为原文,因为这是一个专有名词或方法名称,通常在翻译中保持不变。接下来的部分,“A Novel p-adic Approach for Enhanced Clustering of High-Dimensional scRNASeq Data”,翻译为“一种新颖的p-adic方法,用于增强高维度单细胞RNA测序数据的聚类分析”。这里,“p-adic”是一种数学概念,指的是与素数p相关的数论方法,而“scRNASeq”是单细胞RNA测序的缩写,这在生物学和医学研究中是一个常用的术语。整体翻译旨在准确传达原文的技术内容和应用领域。 | Sharma, P. | PDF | N/A | p-ClustVal: A Novel p-adic Approach for Enhanced Clustering of High-Dimensional scRNASeq Data | | 病理性微环路在患者海马切片中引发癫痫样事件 | Elliott, M. | PDF | N/A | Pathological microcircuits initiate epileptiform events in patient hippocampal slices | | 通过控制肽段身份传播的假发现率(FDR),提高差异丰度蛋白质的检测能力 | Solivais, A. J. | PDF | N/A | Improved detection of differentially abundant proteins through FDR-control of peptide-identity-propagation | | 比较皮质类固醇对人类MR(Ile-180)和人类MR单倍型(Ile180Val)的转录激活作用 | Katsu, Y. | PDF | N/A | Comparison of Transcriptional Activation by Corticosteroids of Human MR (Ile-180) and Human MR Haplotype (Ile180Val) | | 通过NMDA受体GluN2B羧基末端域的非离子型信号传导驱动树突棘的形态可塑性,并逆转小鼠海马中的脆性X综合征表型。 | Barnes, S. A. | PDF | N/A | Non-ionotropic signaling through the NMDA receptor GluN2B carboxy terminal domain drives morphological plasticity of dendritic spines and reverses fragile X phenotypes in mouse hippocampus | | 随机生长爆发使单个细菌能够无负担地生产鞭毛 | Garcia-Alcala, M. | PDF | N/A | Stochastic Growth Bursts Enable Burden-Free Flagellum Production in a Single Bacterium | | PI3Kα的RAS结合域的共价抑制剂能够抑制由RAS和HER2驱动的肿瘤生长。 | Klebba, J. E. | PDF | N/A | Covalent inhibitors of the RAS binding domain of PI3Ka impair tumor growth driven by RAS and HER2 | | 在生物学黎明时期的结构酶学、系统发育学、分化与符号反身性 | Carter, C. W. | PDF | N/A | Structural Enzymology, Phylogenetics, Differentiation, and Symbolic Reflexivity at the Dawn of Biology | | 主要组织相容性复合体多样性对社会性哺乳动物适应性的性别依赖性影响 | Schubert, N. | PDF | N/A | Sex-dependent influence of major histocompatibility complex diversity on fitness in a social mammal | | 小鼠大脑类器官模型在体内模拟神经发育和功能,并捕捉与人类的差异 | Lloyd-Davies Sanchez, D. J. | PDF | N/A | Mouse brain organoids model in vivo neurodevelopment and function and capture differences to human | | 厄瓜多尔低山地热带雨林中蕨类植物的低度和兼性菌根化现象 | Michel, J. | PDF | N/A | Low and facultative mycorrhization of ferns in a low-montane tropical rainforest in Ecuador | | 随机化空间主成分分析(RASP):一种用于高分辨率空间转录组数据降维的计算高效方法 | Gingerich, I. K. | PDF | N/A | Randomized Spatial PCA (RASP): a computationally efficient method for dimensionality reduction of high-resolution spatial transcriptomics data | | 裂殖酵母中不同细胞位点的内吞斑块动力学受到差异性调控 | Campbell, B. F. | PDF | N/A | Endocytic Patch Dynamics are Differentially Regulated at Distinct Cell Sites in Fission Yeast | | 模拟阿塔卡马地貌中土壤微生物群落的新兴代谢潜力 | Andreani-Gerard, C. M. | PDF | N/A | Modeling the emergent metabolic potential of soil microbiomes in Atacama landscapes | | 解析TULP3与组蛋白去乙酰化酶SIRT1和SIRT2相互作用的分子机制 | Ramu, M. | PDF | N/A | Deciphering the molecular mechanism associated with the interaction of TULP3 and Histone deacetylases, SIRT1 and SIRT2 | | APOE4增加对淀粉样蛋白的易感性,加速情景记忆衰退 | Vanderlip, C. R. | PDF | N/A | APOE4 Increases Susceptibility to Amyloid, Accelerating Episodic Memory Decline | | 经验丰富的冥想者在冲突监控和刺激预期过程中的神经差异,很可能是由增强的注意力驱动的。 | Hill, A. T. | PDF | N/A | Neural differences in conflict monitoring and stimulus expectancy processes in experienced meditators are likely driven by enhanced attention | | 注意力领域作为一种认知行为标记,用于区分互联网成瘾与奖励,但不适用于吸烟成瘾。 | Mao, M. | PDF | N/A | Attention field as a cognitive-behavioral marker for demarcating internet- but not smoking-addiction from reward | | 植物暴露对精神分裂症小鼠社会缺陷的恢复作用

这段翻译将英文标题“The Restoration of Social Defects in Schizophrenic Mice by Plant Exposure”转化为中文,同时保持了原文的学术性和专业性。标题中的“Restoration”翻译为“恢复作用”,强调了植物暴露对精神分裂症小鼠社会缺陷的积极影响。“Social Defects”翻译为“社会缺陷”,指的是小鼠在社交行为上的异常或障碍。“Schizophrenic Mice”翻译为“精神分裂症小鼠”,指的是用于研究精神分裂症的动物模型。“Plant Exposure”翻译为“植物暴露”,指的是小鼠与植物的接触或处于植物环境中的情况。整个标题清晰地传达了研究的核心内容,即通过植物暴露来恢复精神分裂症小鼠的社会缺陷。 | Li, M. | PDF | N/A | The Restoration of Social Defects in Schizophrenic Mice by Plant Exposure | | 弹性蛋白酶介导的脑小血管病中的白质损伤:小胶质细胞与中性粒细胞的双人舞

(注:这里的“pas de deux”是法语,意为“双人舞”,在医学文献中常用来形象地描述两种细胞或分子之间的相互作用或协同效应。) | Dong, C.-Y. | PDF | N/A | Elastase mediated white matter damage in cerebral small vessel disease: Microglia - neutrophils pas de deux | | 流动迅速补充稀缺的营养物质,以促进细菌的生长。 | Padron, G. C. | PDF | N/A | Flow rapidly replenishes scarce nutrients to promote bacterial growth | | SAR11中的生境特异性与少数受到高度选择的基因相关。 | Tucker, S. J. | PDF | N/A | Habitat-specificity in SAR11 is associated with a handful of genes under high selection | | 在沉默信息调节因子异染色质复合体中,新颖的相互作用增强了亚基间的通讯和基因抑制。 | Kotz, J. | PDF | N/A | Novel interactions within the silent information regulator heterochromatin complex potentiate inter-subunit communication and gene repression | | 秀丽隐杆线虫(C. elegans)中的LET-381/FoxF和DMD-4/DMRT调控中胚层HMC内皮细胞的发育。 | Stefanakis, N. | PDF | N/A | C. elegans LET-381/FoxF and DMD-4/DMRT control development of the mesodermal HMC endothelial cell | | 组蛋白H4限制果蝇组蛋白基因座的转录 | Ahmad, K. | PDF | N/A | Histone H4 limits transcription of the histone locus in Drosophila | | 补丁:一种用于解码伤口愈合中共享和条件特异性转录程序的表示学习框架 | Beker, O. | PDF | N/A | Patches: A Representation Learning framework for Decoding Shared and Condition-Specific Transcriptional Programs in Wound Healing | | 系统性质粒工程用于细菌中目标类胡萝卜素的合成 | Furubayashi, M. | PDF | N/A | Systematic Plasmid Engineering for Targeted Carotenoid Synthesis in Bacteria | | Lep-Rec的交叉模型揭示了重组具有更高的遗传性。 | Rastas, P. M. A. | PDF | N/A | Crossover model of Lep-Rec reveals higher heritability of recombination | | 脂质双分子层决定了环磷酸腺苷(cAMP)与起搏通道结合的所有osteric效应,但不影响其内在亲和力。 | Idikuda, V. | PDF | N/A | Lipid bilayers determine the allostery but not intrinsic affinity of cAMP binding to pacemaker channels | | 表面负电荷在激动剂结合到神经肌肉乙酰胆碱受体未配体开放状态中的作用 | Khatoon, N. | PDF | N/A | Role of surface negative charges in agonist binding to the unliganded open state of the neuromuscular acetylcholine receptor | | 表达VSIG4的巨噬细胞在腹膜腔中对抗寄生虫和抗转移反应中的作用

这段翻译保留了原文的科学性和专业性,同时确保了中文表达的准确性和流畅性。翻译中,“VSIG4-Expressing Macrophages”被译为“表达VSIG4的巨噬细胞”,直接传达了原文中巨噬细胞表达VSIG4蛋白的信息。“Contribute To”译为“在……中起作用”,符合中文表达习惯,同时也准确传达了原文中巨噬细胞在特定生理过程中的作用。“Anti-Parasitic And Anti-Metastatic Responses”被译为“对抗寄生虫和抗转移反应”,清晰地表达了巨噬细胞在腹膜腔中的两种主要功能。“Peritoneal Cavity”译为“腹膜腔”,是医学术语,确保了翻译的专业性。整体翻译既忠实于原文,又符合中文表达习惯,易于理解。 | Van Ginderachter, J. A. | PDF | N/A | VSIG4-Expressing Macrophages Contribute To Anti-Parasitic And Anti-Metastatic Responses In The Peritoneal Cavity | | 在卡波西肉瘤相关疱疹病毒(KSHV)感染期间,干扰素-β(Interferon-β)的诱导异质性是由干扰素-β增强体(enhanceosome)转录因子而非IRF3决定的。 | Kaku, M. | PDF | N/A | Interferon-β induction heterogeneity during KSHV infection is determined by interferon-β enhanceosome transcription factors other than IRF3 | | 对于小立碗藓(Physcomitrium patens)原丝体发育至关重要的过程,需要由功能冗余的PpROP GTPases提供的不同水平的总活性。 | Le Bail, A. | PDF | N/A | Processes essential for Physcomitrium patens protonemal development require distinct levels of total activity provided by functionally redundant PpROP GTPases | | 乳腺癌患者外周血淋巴细胞中DNA双链断裂与细胞死亡之间的相关性 | Solana-Pena, A. | PDF | N/A | Correlation between DNA double strand breaks and cell death in peripheral blood lymphocytes from breast cancer patients | | 基于规则的二萜类化合物库解构与重建:模式分类与结构景观解析

这段翻译将英文标题“Rule-Based Deconstruction and Reconstruction of Diterpene Libraries: Categorizing Patterns & Unravelling the Structural Landscape”转化为中文,同时保留了原文的专业性和准确性。翻译后的标题清晰地传达了原文的核心内容,即通过基于规则的方法对二萜类化合物库进行解构和重建,进而对化合物模式进行分类并解析其结构景观。 | Mathieu, D. | PDF | N/A | Rule-Based Deconstruction and Reconstruction of Diterpene Libraries: Categorizing Patterns & Unravelling the Structural Landscape | | YAP通过与RIF1相互作用来缓解鳞状细胞癌中的复制应激。 | Bojko, J. | PDF | N/A | YAP engages RIF1 to dampen replication stress in squamous cell carcinoma. | | 硝基化动力学失调促进亚硝化应激并导致射血分数保留型心脏代谢性心力衰竭 | Li, Z. | PDF | N/A | Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction | | 解码由RAR特异性激动剂驱动的神经元-星形胶质细胞命运转变过程中的转录身份 | Galindo-Albarran, A. | PDF | N/A | Decoding transcriptional identity during Neuron-Astroglia Cell Fate driven by RAR-specific agonists | | TSvelo:通过联合建模转录与剪接实现全面的RNA速度推断

RNA速度是一种利用未剪接和剪接mRNA的动态变化来推断细胞未来状态的技术。TSvelo方法通过同时考虑转录和剪接过程,提供了一种更全面的RNA速度推断框架。这种方法能够更准确地捕捉细胞状态的动态变化,从而在单细胞RNA测序数据分析中提供更深入的见解。 | Li, J. | PDF | N/A | TSvelo: Comprehensive RNA velocity inference by jointly modeling Transcription and Splicing | | 重新思考癌症药物协同作用预测:呼吁机器学习应用的标准化 | Wong, A. M. | PDF | N/A | Rethinking cancer drug synergy prediction: a call for standardization in machine learning applications | | 活体出血脑中的髓系细胞单细胞时间图谱 | Kawamura, Y. | PDF | N/A | Single-Cell Temporal Atlas of Myeloid Cells in the Live Haemorrhagic Brain | | 揭示石油中的古代DNA:洞察地球隐秘生命事件与地质历史 | Zhao, W.-Q. | PDF | N/A | Uncovering Ancient DNA in Petroleum: Insights into Earth Hidden Life Events and Geological History | | 这段英文翻译成中文是:“一种女巫扫帚植原体效应蛋白通过稳定植物中的bHLH转录因子来诱导矮化。” | Yang, S. | PDF | N/A | A Witches' Broom Phytoplasma effector induces stunting by stabilizing a bHLH transcription factor in plants | | 远程检测浮游水生植被的红边光谱特征 | Murakami, A. | PDF | N/A | Remote Detection of Red-Edge Spectral Characteristics in Floating Aquatic Vegetation | | 工程化改造大麦NLR中的Exo70整合结构域以增强稻瘟病抗性 | Saado, I. | PDF | N/A | Engineering an Exo70 integrated domain of a barley NLR for improved blast resistance | | 在Pink1基因敲除小鼠和野生型小鼠中,单次感染啮齿柠檬酸杆菌(Citrobacter rodentium)会导致局部血脑屏障扰动和胶质细胞激活,但不会引起多巴胺神经元轴突末端的损失。 | Mukherjee, S. | PDF | N/A | A single Citrobacter rodentium infection in Pink1 knockout and wild type mice leads to regional blood-brain-barrier perturbation and glial activation without dopamine neuron axon terminal loss | | GJB2的细胞特异性递送恢复了DFNB1耳聋小鼠模型的听觉功能,并在非人灵长类动物(NHP)耳蜗中实现了适当的表达。 | Ivanchenko, M. V. | PDF | N/A | Cell-specific delivery of GJB2 restores auditory function in mouse models of DFNB1 deafness and mediates appropriate expression in NHP cochlea | | 与行为强化相关的奖励表征的重新激活 | Tong, A. P. S. | PDF | N/A | Reactivation of reward representations associated with the reinforcement of behavior | | 新分离的基因组和全球海洋宏基因组揭示了SAR11的生态相关单元。 | Freel, K. C. | PDF | N/A | New isolate genomes and global marine metagenomes resolve ecologically relevant units of SAR11 | | 专家世界中的通才:具有广泛宿主范围的弧菌噬菌体

在这个由专家主导的世界里,弧菌噬菌体以其广泛的宿主范围脱颖而出,成为了微生物领域中的“通才”。这些噬菌体能够感染多种不同的弧菌菌株,展现出独特的适应能力和多样性。它们的存在不仅挑战了我们对宿主-噬菌体关系的传统理解,也为开发新型抗菌策略提供了宝贵的资源。通过研究这些具有广泛宿主范围的弧菌噬菌体,科学家们希望能够揭示其背后的分子机制,并探索其在控制弧菌感染、维护水生生态系统健康以及促进食品安全等方面的潜在应用。 | Bernard, C. | PDF | N/A | Generalists in a Specialist World: Vibrio-Phages with Broad Host Range | | 在长链非编码RNA DRAIC中,存在一个由可变剪接调控的36个碱基的发夹结构,该结构与IKKα的卷曲螺旋域相互作用,并抑制NF-kB及肿瘤细胞表型。 | Hao, X. | PDF | N/A | A 36-base hairpin within lncRNA DRAIC, which is modulated by alternative splicing, interacts with the IKKα coiled-coil domain and inhibits NF-kB and tumor cell phenotypes | | 香烟烟雾通过氧化应激诱导PPP1R15A,从而调节支气管上皮细胞的炎症细胞因子产生。 | Amatngalim, G. D. | PDF | N/A | Cigarette smoke induces PPP1R15A via oxidative stress to modulate inflammatory cytokine production by bronchial epithelial cells | | 恢复氧化磷酸化可增强线粒体DNA翻译缺陷的人骨髓间充质干细胞的成骨能力。 | Fernandez Guerra, P. | PDF | N/A | Restoring oxidative phosphorylation enhances osteogenesis in mitochondrial DNA translation defective human bone marrow stromal cells | | 横跨美国本土的冠层高度模型与NAIP影像对 | Allred, B. W. | PDF | N/A | Canopy height model and NAIP imagery pairs across CONUS | | 增强的多功能性和便利性:ReMOT介导的昆虫基因修饰技术的进展与策略优化 | Liang, X. | PDF | N/A | Increased versatility and convenience: advances and strategy optimization of ReMOT-mediated genetic modification in insects | | 鸡腿颜色由抑制皮肤黑色素(ID)决定,这一过程通过一种调控CDKN2A表达的结构变异来介导。 | Li, J. | PDF | N/A | Chicken shank color determined by Inhibition of dermal melanin (ID) is mediated by a structural variation regulating CDKN2A expression | | 全基因组范围内利用双链DNA脱氨酶绘制真核生物开放染色质区域图谱 | Dong, W. | PDF | N/A | Genome-wide Mapping Eukaryotic Open Chromatin Regions with Double-Stranded DNA Deaminase | | 狗基因组中的候选印记控制区域 | Wyss, P. | PDF | N/A | Candidate imprinting control regions in dog genome | | 通过体外重构研究自噬货物招募和膜扩张的机制 | Zhang, W. | PDF | N/A | Mechanistic studies of autophagic cargo recruitment and membrane expansion through in vitro reconstitution | | ISCO:用于类器官精确分割与对比分析的智能框架 | ZHOU, J. | PDF | N/A | ISCO: Intelligent Framework for Accurate Segmentation and Comparative Analysis of Organoids | | 用于批量及单细胞Hi-C数据中染色质环注释的通用工具 | Hou, Y. | PDF | N/A | A universal tool for chromatin loop annotation in bulk and single-cell Hi-C data | | 揭示诊疗潜力:深入探索无细胞微RNA-蛋白质相互作用 | Sahu, V. K. | PDF | N/A | Unveiling theranostic potential: Insights into cell-free microRNA-protein interactions | | 以下是这段英文的中文翻译:

山羊乳清蛋白源生物活性肽作为胰脂肪酶和α-淀粉酶抑制剂的蛋白质组学表征及分子机制研究

翻译说明: 1. Proteomic Characterization 翻译为“蛋白质组学表征”,指通过蛋白质组学技术对生物活性肽进行分析和鉴定。 2. Molecular Mechanism 翻译为“分子机制”,指研究生物活性肽抑制胰脂肪酶和α-淀粉酶的具体分子作用机制。 3. Goat Whey Protein-Derived Bioactive Peptides 翻译为“山羊乳清蛋白源生物活性肽”,指从山羊乳清蛋白中提取或衍生的具有生物活性的肽段。 4. Pancreatic Lipase and alpha-Amylase Inhibitors 翻译为“胰脂肪酶和α-淀粉酶抑制剂”,指这些生物活性肽具有抑制胰脂肪酶和α-淀粉酶活性的功能。

希望这个翻译对你有帮助!如果需要进一步调整或补充,请随时告诉我。 | Sansi, M. S. | PDF | N/A | Proteomic Characterization and Molecular Mechanism of Goat Whey Protein-Derived Bioactive Peptides as Pancreatic Lipase and alpha-Amylase Inhibitors | | 错义突变:骨架结构位置效应 | Perez Martell, R. I. | PDF | N/A | Missense mutations: Backbone structure positional effects | | 将“Identification of SMARCA1 as a key regulator for Colorectal Cancer”翻译成中文为:

“SMARCA1被鉴定为结直肠癌的关键调控因子”

这个翻译准确表达了原文的含义,即SMARCA1在结直肠癌中扮演着重要的调控角色。 | Fu, C. | PDF | N/A | Identification of SMARCA1 as a key regulator for Colorectal Cancer | | 肝脏微循环的激光散斑成像 | Zhukov, O. | PDF | N/A | Laser speckle imaging of hepatic microcirculation | | 温度对早期胚胎细胞周期影响的机制起源 | Rombouts, J. | PDF | N/A | Mechanistic origins of temperature scaling in the early embryonic cell cycle | | 以下是这段文字的中文翻译:

儿童阅读障碍中的非典型视觉选择性注意:来自N2pc和PD的证据

翻译说明: - Atypical:非典型的,指与正常情况不同。 - Visual Selective Attention:视觉选择性注意,指在视觉信息中选择性地关注某些刺激而忽略其他刺激的能力。 - Dyslexia:阅读障碍,一种学习障碍,主要表现为阅读困难。 - Evidence from N2pc and PD:来自N2pc和PD的证据。N2pc和PD是脑电图(EEG)中的两个成分,分别与选择性注意和干扰抑制相关。

整体翻译传达了原文的核心内容,即通过N2pc和PD这两个脑电成分,研究阅读障碍儿童在视觉选择性注意方面的非典型表现。 | Liu, H. | PDF | N/A | Atypical Visual Selective Attention in Children with Dyslexia: Evidence from N2pc and PD | | 溶组织内阿米巴(Entamoeba histolytica)的细胞外囊泡驱动促炎性单核细胞信号传导 | Honecker, B. | PDF | N/A | Entamoeba histolytica extracellular vesicles drive pro-inflammatory monocyte signaling | | 以下是这段英文的中文翻译:

按性别划分的冈比亚按蚊胚胎发育过程中的转录组动态

翻译说明: - "Sex-specific" 翻译为“按性别划分的”,表示研究关注的是性别差异。 - "transcriptome dynamics" 翻译为“转录组动态”,指的是基因表达的变化过程。 - "Anopheles gambiae" 是“冈比亚按蚊”,一种传播疟疾的蚊子。 - "during embryonic development" 翻译为“胚胎发育过程中”,表示研究的时间范围。

整句话的意思是研究冈比亚按蚊在胚胎发育过程中,不同性别的基因表达变化。 | Kalita, A. I. | PDF | N/A | Sex-specific transcriptome dynamics of Anopheles gambiae during embryonic development | | 以下是这段英文的中文翻译:

分子对嗜铬粒蛋白B的需求:长期以来寻找的调节分泌的阴离子分流器

翻译解释: - "Molecular requirements" 翻译为 "分子需求" 或 "分子要求"。 - "chromogranin B" 是专业术语,直接保留英文名称 "嗜铬粒蛋白B"。 - "long-sought" 翻译为 "长期以来寻找的"。 - "anion shunter" 翻译为 "阴离子分流器"。 - "regulated secretion" 翻译为 "调节分泌"。

希望这个翻译对你有帮助!如果有其他问题,请随时告诉我。 | Yadav, G. P. | PDF | N/A | Molecular requirements of chromogranin B for the long-sought anion shunter of regulated secretion | | 不同基因型的微囊藻对青鳉鱼造成的独特生态毒理学损害 | MARIE, B. | PDF | N/A | Distinct ecotoxicological impairs induced by different Microcystis genotypes to Medaka fish | | 基于RiboTag的RNA测序揭示了自身免疫性脑脊髓炎中少突胶质细胞谱系特异性炎症 | Wang, Y. | PDF | N/A | RiboTag-based RNA-Seq uncovers oligodendroglial lineage-specific inflammation in autoimmune encephalomyelitis | | 通过耳蜗电图评估人类对侧传出效应 | Verschooten, E. | PDF | N/A | Assessment of Contralateral Efferent Effects in Human Via ECochG | | 以下是这段英文的中文翻译:

马达加斯加新型蝙蝠科布病毒的基因组特征:对病毒进化与人畜共患风险的启示

翻译说明: - "Genomic characterization" 译为“基因组特征”或“基因组表征”。 - "novel bat kobuviruses" 译为“新型蝙蝠科布病毒”,其中“novel”表示新发现的,“kobuviruses”是科布病毒(一种小RNA病毒)。 - "Madagascar" 译为“马达加斯加”,是非洲东南部的一个岛国。 - "implications for" 译为“对……的启示”或“对……的意义”。 - "viral evolution" 译为“病毒进化”。 - "zoonotic risk" 译为“人畜共患风险”,指病毒从动物传播给人类的潜在风险。

整段翻译强调了研究马达加斯加蝙蝠科布病毒的基因组特征,以了解其进化过程及其可能对人类健康构成的威胁。 | Gonzalez, F. L. | PDF | N/A | Genomic characterization of novel bat kobuviruses in Madagascar: implications for viral evolution and zoonotic risk | | 地衣Cladonia rangiformis的参考宏基因组序列 | Heuberger, M. | PDF | N/A | A reference metagenome sequence of the lichen Cladonia rangiformis | | sc-SPLASH 提供了在带有条形码的单细胞测序中进行超高效的无参考序列发现。 | Dehghannasiri, R. | PDF | N/A | sc-SPLASH provides ultra-efficient reference-free discovery in barcoded single-cell sequencing | | 一种可通过光调控代谢型谷氨酸受体5激活的光开关正变构调节剂 | Dumazer, A. | PDF | N/A | A photoswitchable positive allosteric modulator to control the activation of the metabotropic glutamate receptor 5 by light | | 童年交替性偏瘫与Atp1a3基因突变相关的研究揭示了小鼠中多样化的神经学改变。 | Terrey, M. | PDF | N/A | Alternating hemiplegia of childhood associated mutations in Atp1a3 reveal diverse neurological alterations in mice. | | SHEN-LONG,一个新型的心脏调控位点,调控多能干细胞衍生的心肌细胞中的心脏主转录因子NKX2-5。 | Scarafia, M. A. | PDF | N/A | SHEN-LONG, a novel cardiac regulatory locus, regulates cardiac master transcription factor NKX2-5 in pluripotent stem cell derived cardiomyocytes | | DOC2b富集通过减弱人胰岛中的IKKβ和STAT-1信号传导,缓解促炎细胞因子诱导的CXCL10表达。 | Chatterjee Bhowmick, D. | PDF | N/A | DOC2b enrichment mitigates proinflammatory cytokine-induced CXCL10 expression by attenuating IKKβ and STAT-1 signaling in human islets | | pipemake:一个使用Snakemake的管道创建工具,用于生物数据集的可重复分析 | Webb, A. E. | PDF | N/A | pipemake: A pipeline creation tool using Snakemake for reproducible analysis of biological datasets | | 以COVID-19为模型抗原,研究癌症手术患者术后T细胞和B细胞功能障碍的特征 | Olanubi, O. | PDF | N/A | Characterizing postoperative T and B cell dysfunction in cancer surgery patients, using COVID-19 as a model antigen |