BioRxiv 2024-12-30 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 一种在中枢神经系统全细胞膜片钳记录中可靠测量微型及自发性突触后电位/电流的新方法 | Dervinis, M. | N/A | A novel method for reliably measuring miniature and spontaneous postsynaptic potentials/currents in whole-cell patch clamp recordings in the central nervous system | |
| 利用多功能蛋白质组学工具绘制GALNT1底物图谱 | Saei, A. A. | N/A | Mapping the GALNT1 substrate landscape with versatile proteomics tools | |
| 对炎症反应元件的多物种分析揭示了转座元件对NF-κB结合的古老和谱系特异性贡献 | Wang, L. | N/A | Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding | |
| 婚赠行为演化的通用模型 | Charmouh, A. P. | N/A | A general model for the evolution of nuptial gift-giving | |
| 一个用于量化流感病毒mRNA核输出速率的统计框架。 | Miura, M. | N/A | A statistical framework for quantifying the nuclear export rate of influenza viral mRNAs. | |
| 合成控制方法消除了在单细胞和空间转录组数据分析中因重复使用数据而产生的虚假发现。 | Song, D. | N/A | Synthetic control removes spurious discoveries from double dipping in single-cell and spatial transcriptomics data analyses | |
| 将互惠网络从物种层面缩小到个体层面，揭示了植物种群内一致的互动生态位和角色。 | Quintero, E. | N/A | Downscaling mutualistic networks from species to individuals reveals consistent interaction niches and roles within plant populations | |
| 由SARS-CoV-2 NSP6和SARS-CoV-2调控的miRNAs影响的大脑、心脏和肺部的通路：一项提示癌症发病率的计算机模拟研究 | Chatterjee, S. | N/A | Pathways in the brain, heart, and lung influenced by SARS-CoV-2 NSP6 and SARS-CoV-2 regulated miRNAs: an in silico study hinting cancer incidence | |
| 顺铂对蛋白质磷酸化的重编程 | Qi, L. | N/A | Cisplatin reprogramming of protein phosphorylation | |
| 《从土壤到地表：探索绿色基础设施对建筑环境中微生物群落的影响》 | Mcgonigal, M. | N/A | From Soil to Surface: Exploring the Impact of Green Infrastructure on Microbial Communities in the Built Environment | |
| 《非适应性精子的扩散搜索建模：实证与计算洞察》 | Brisard, B. M. | N/A | Modeling Diffusive Search by Non-Adaptive Sperm: Empirical and Computational Insights | |
| 从PacBio HiFi数据中估算基因转换片段长度和速率 | Charmouh, A. P. | N/A | Estimating gene conversion tract length and rate from PacBio HiFi data | |
| 新型量子分析方法揭示了不同大小皮质锥体神经元之间兴奋性突触电量的平均守恒性。 | Dervinis, M. | N/A | Novel quantal analysis method reveals conservation of average excitatory synaptic charge across cortical pyramidal neurons of different sizes | |
| 从无人机上记录的蝴蝶运动描绘了它们在野外的迁徙飞行行为。 | de Margerie, E. | N/A | Butterfly movements recorded from a UAV depict migratory flight behaviour in the wild. | |
| 星形胶质细胞衍生的MFG-E8促进阿尔茨海默病小鼠模型中的小胶质细胞突触消除。 | Sokolova, D. | N/A | Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models | |
| 原料和制造环境作为味噌微生物群落的决定因素。 | Ito, K. | N/A | Raw materials and manufacturing environment as determinants of miso microbial community. | |
| 结构和功能证据支持将小鼠的高阶视觉区域重新定义为一个单一的V2区。 | Rowley, D. P. | N/A | Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2 | |
| 半球间和半球内的前庭信号来源对V1的影响 | Bouvier, G. | N/A | Inter- and Intrahemispheric Sources of Vestibular Signals to V1 | |
| 在刺激呈现之后：在自由观察过程中，对物体内部的持续注视不会重新唤起类别表征。 | Auerbach-Asch, C. R. | N/A | Beyond stimulus onset: Ongoing fixations within an object do not re-evoke category representations during free-viewing. | |
| 通过对大量天然配对的人类抗体序列和结构数据的大规模分析，揭示了保守的重链/轻链接触区域以及种系偏好性。 | Dudzic, P. | N/A | Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data. | |
| singIST：一种用于疾病模型与人类之间单细胞转录组学比较的综合方法 | Moruno-Cuenca, A. | N/A | singIST: an integrative method for comparative single-cell trancriptomics between disease models and humans | |
| JMJD6与YBX1发生物理相互作用并调控HOTAIR近端启动子 | Gupta, A. | N/A | JMJD6 and YBX1 physically interact and regulate HOTAIR proximal promoter | |
| 大豆根质外体蛋白质组分析结合AlphaFold预测揭示了大豆炭疽病菌（Macrophomina phaseolina）的侵染策略及工程抗性的潜在靶点 |
这段翻译将原文的科学研究内容准确地转化为中文，同时保持了专业术语的准确性，如“Proteome Analysis”翻译为“蛋白质组分析”，“Apoplast”翻译为“质外体”，“AlphaFold”保留原文，“Macrophomina phaseolina”翻译为“大豆炭疽病菌”，“Infection Strategies”翻译为“侵染策略”，“Engineering Resistance”翻译为“工程抗性”。整体翻译流畅，符合学术论文的表达习惯。 | Veeraganti Naveen Prakash, C. | PDF | N/A | Proteome Analysis of Soybean Root Apoplast Combined with AlphaFold Prediction Reveal Macrophomina phaseolina Infection Strategies and Potential Targets for Engineering Resistance | | NeoPhAR：下一代噬菌体疗法应对抗菌素耐药性 | Rivera-Orellana, S. | PDF | N/A | NeoPhAR: Next-generation Phage Therapy for Antimicrobial Resistance | | HDAC3在成年心脏中的非酶依赖性功能 | Qian, S. | PDF | N/A | Enzyme-independent functions of HDAC3 in the adult heart | | 一种用于小鼠临床前MRI的3D打印支架，配备集成水加热系统 | Gaudin, R. | PDF | N/A | A 3D-printed cradle for mouse preclinical MRI with an integrated water heating system | | 在受损的老年哺乳动物皮层中，轴突再生受损且突触动态增强 | Bass, C. | PDF | N/A | Impaired axon regeneration and heightened synaptic dynamics in the injured aged mammalian cortex | | 线虫种类Agriotes obscurus、A. sputator和A. lineatus与新型颗粒制剂Metarhizium brunneum的相互作用 | Paluch, M. | PDF | N/A | Interaction of the wireworm species Agriotes obscurus, A. sputator and A. lineatus with a new granule formulation of Metarhizium brunneum | | 两种新型绿僵菌制剂在防治马铃薯种植中金针虫的效果 | Paluch, M. | PDF | N/A | The effectiveness of two new Metarhizium brunneum formulations against wireworms in potato cultivation | | 探索印度中部黑土的微生物组及农业实践对土壤微生物群落的影响 | Kumar, S. | PDF | N/A | Exploring the microbiome of black soil from Central India and the impacts of agricultural practices on soil microbial communities | | 《胃癌中的生物信息学驱动的ceRNA网络：新型预后mRNA-miRNA-lncRNA相互作用的鉴定》 | Kamal, E. | PDF | N/A | A Bioinformatics-Driven ceRNA Network in Stomach Adenocarcinoma: Identification of Novel Prognostic mRNA-miRNA-lncRNA Interactions | | NeuroTorch：一个面向神经科学的机器学习Python库 | Gince, J. | PDF | N/A | NeuroTorch: A Python library for neuroscience-oriented machine learning | | RNA结合蛋白Staufen与Tm1-I/C之间的直接相互作用调控了oskar mRNP的组成与运输。 | Gaber, T. | PDF | N/A | A direct interaction between the RNA-binding proteins Staufen and Tm1-I/C regulates oskar mRNP composition and transport | | 自体血清对体外肉芽肿模型的影响：研究结核分枝杆菌感染动态 | Bourg, C. | PDF | N/A | Impact of autologous serum on an in vitro granuloma model to study Mycobacterium tuberculosis infection dynamics | | 小麦白粉病菌中序列多样的效应蛋白通过与相应免疫受体的相互作用，决定了识别的特异性。 | Isaksson, J. | PDF | N/A | Interactions of sequence diverse effector proteins of wheat powdery mildew control recognition specificity by the corresponding immune receptor | | 通过膜蛋白质组学分析揭示，磷酸盐饥饿条件下拟南芥根中膜货物依赖于CORNICHON HOMOLOG 5的ER输出。 | Liu, T.-Y. | PDF | N/A | CORNICHON HOMOLOG 5-dependent ER export of membrane cargoes in phosphate-starved Arabidopsis root as revealed by membrane proteomic analysis | | 人类肠道微生物组基因共表达网络揭示了帕金森病中分类和功能多样性的丧失 | Villette, R. | PDF | N/A | Human gut microbiome gene co-expression network reveals a loss in taxonomic and functional diversity in Parkinson's disease | | 基底纤毛而非胞质中的PKA特异性调控Smoothened下游的HH信号通路。 | Zhang, H. | PDF | N/A | The Basal Ciliary but not Cytosol PKA Specifically Regulates HH Pathway Downstream of Smoothened | | 组织损伤通过调控命运转导的侧向抑制回路加速干细胞分化 | Sanders, E. N. | PDF | N/A | Organ injury accelerates stem cell differentiation by modulating a fate-transducing lateral inhibition circuit | | CLCNet：一种用于植物基因组预测的对比学习与染色体感知网络 | Huang, J. | PDF | N/A | CLCNet: a contrastive learning and chromosome-aware network for genomic prediction in plants | | 基于模型的贝叶斯推断在异质性纵向数据中的癌症动态分析 | Santacatterina, G. | PDF | N/A | Model-based Bayesian inference of cancer dynamics from heterogenous longitudinal data | | 卡泰斯塔汀通过促进线粒体结构和功能，提高心脏代谢的灵活性。 | Chirasani, V. R. | PDF | N/A | Catestatin improves heart metabolic flexibility by promoting mitochondrial structure and function | | 葡萄藤从幼年期到成年期营养生长阶段转变的转录组调控 | Ferradas, Y. | PDF | N/A | Transcriptomic regulation of juvenile-to-adult vegetative phase transition in grapevine | | 我们能否从群体活动的频谱中推断出兴奋-抑制平衡？ | Chakravarty, K. | PDF | N/A | Can we infer excitation-inhibition balance from the spectrum of population activity? | | 肠道细菌产生的鞘脂类物质调节失调的皮肤脂质稳态 | Lee, M.-T. | PDF | N/A | Gut bacterial sphingolipid production modulates dysregulated skin lipid homeostasis | | 共生细菌伙伴通过化学防御在海洋海绵中垂直传播 | Fujita, M. | PDF | N/A | Symbiotic Bacterial Partners for Chemical Defense are Vertically Transmitted in a Marine Sponge | | 在序列适应度景观中，倒置的拓扑结构能够实现进化控制。 | Chen, P. | PDF | N/A | Inverted topologies in sequential fitness landscapes enable evolutionary control | | 外周血管移植中植入材料和吻合角度对血流动力学的影响 | Schoenborn, S. | PDF | N/A | Haemodynamic impact of implant materials and anastomotic angle in peripheral vascular grafts | | 基因转换指导的模块化聚酮合酶连续工程 | Jin, W. | PDF | N/A | Gene Conversion Directed Successive Engineering of Modular Polyketide Synthases | | p47的新型伴侣蛋白活性调控力介导的从内质网到细胞质的逆向转运 | Haldar, S. | PDF | N/A | The Novel Chaperone Activity of p47 Modulates Force-Mediated Retrotranslocation from the Endoplasmic Reticulum to the Cytosol | | 致癌基因KRAS的转录剂量驱动肺腺癌细胞状态、进展和转移
这段文字可以翻译为：“致癌基因KRAS的转录剂量驱动肺腺癌细胞状态、进展和转移。” 其中，“Transcriptional Dosage”指的是基因转录的剂量或水平，“Oncogenic KRAS”是指具有致癌潜能的KRAS基因，“Drives”表示驱动或促使，“Lung Adenocarcinoma”是肺腺癌，“Cell States”指细胞的状态，“Progression”表示疾病的进展，“Metastasis”则是指癌症的转移。 | Serresi, M. | PDF | N/A | Transcriptional Dosage of Oncogenic KRAS Drives Lung Adenocarcinoma Cell States, Progression and Metastasis | | 癌症 vs. 对话式人工智能 | Kawchak, K. | PDF | N/A | Cancer vs. Conversational Artificial Intelligence | | 小分子反向激动剂VUF16840对非典型趋化因子受体ACKR3的组成型活性的抑制。 | Bosma, R. | PDF | N/A | Inhibition of constitutive activity of the atypical chemokine receptor ACKR3 by the small-molecule inverse agonist VUF16840 | | 直接RNA牛津纳米孔测序技术能够区分tRNA中U34位点的修饰。 | Kusmirek, W. | PDF | N/A | Direct RNA Oxford Nanopore sequencing distinguishes between modifications in tRNA at the U34 position | | H3K4-H3K9组蛋白甲基化模式与癌胎发育网络作为儿童高级别胶质瘤细胞命运决定的驱动因素 | Uthamacumaran, A. | PDF | N/A | H3K4-H3K9 Histone Methylation Patterns and Oncofetal Developmental Networks as Drivers of Cell Fate Decisions in Pediatric High-Grade Gliomas | | 猴子在路径规划任务中背侧前运动皮层与集合相关神经活动的多样性 | Sakamoto, K. | PDF | N/A | Diversity of set-related neuronal activity in the dorsal premotor cortex of monkeys during a path-planning task | | 不同认知状态下健康老年人认知储备的电生理相关性 | Zhunussova, A. | PDF | N/A | Electrophysiological correlates of cognitive reserve in healthy older adults at different cognitive states | | 研究感觉运动空间依赖性在塑造对虚拟3D物体的意识访问中的作用 | Motyka, P. | PDF | N/A | Investigating the role of sensorimotor spatial dependencies in shaping conscious access to virtual 3D objects | | 在猕猴的颞上沟中，头部和身体方向的整合特异地针对直立的身体。 | Zafirova, Y. | PDF | N/A | Integration of head and body orientations in the macaque superior temporal sulcus is specific to upright bodies | | 小鼠大脑中转录组、形态学和电生理学细胞类型密度的定量空间图谱 | Veraszto, C. | PDF | N/A | A quantitative spatial atlas of transcriptomic, morphological, and electrophysiological cell type densities in the mouse brain | | Layilin调节皮肤中调节性T细胞的运动性和抑制能力 | Gouirand, V. | PDF | N/A | Layilin Regulates Treg Motility and Suppressive Capacity in Skin | | 一种基于第四代完全删除腺病毒载体的强效大流行禽流感病毒疫苗 | Qi, Y. | PDF | N/A | A Potent Pandemic Avian Influenza Virus Vaccine Based on a 4th Generation Fully Deleted Adenoviral Vector | | 免疫细胞单细胞RNA测序分析揭示了一种与年龄相关的T细胞亚群与症状性良性前列腺增生的关联。 | Broman, M. | PDF | N/A | Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia | | 一个无菌损伤的微生理系统通过巨噬细胞来源的细胞外囊泡的相互作用展示了中性粒细胞的反向迁移。 | Babatunde, K. A. | PDF | N/A | A microphysiological system of sterile injury demonstrates neutrophil reverse migration via macrophage-derived extracellular vesicle crosstalk. | | 单细胞RNA测序结合TCR测序揭示小鼠淋巴和非淋巴组织中双TCR Treg细胞的比例及特性 | Xu, Y. | PDF | N/A | scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues | | 开发一种针对鸭IFN-γ蛋白的单克隆抗体及其在细胞内细胞因子染色中的应用 | Chen, Y. | PDF | N/A | Development of a monoclonal antibody against duck IFN-γ protein and the application for Intracellular Cytokine Staining | | 镉的摄入不会破坏亚社会性昆虫幼体间微生物群落的社会传播。 | Cheutin, M.-C. | PDF | N/A | Cadmium ingestion does not disrupt the social transmission of the microbiome in juveniles of a subsocial insect | | 在无症状的旱季感染期间，恶性疟原虫（Plasmodium falciparum）表达的var基因数量较少，且表达水平低于临床疟疾病例。 | Ceesay, S. | PDF | N/A | Plasmodium falciparum expresses fewer var genes at lower levels during asymptomatic dry season infections than clinical malaria cases | | 原生生物作为复杂微生物和病毒关联的媒介 | Schulz, F. | PDF | N/A | Protists as mediators of complex microbial and viral associations | | 利用CRISPR-Cas技术快速鉴定诊断样本中的非洲猪瘟病毒 | Kambakam, S. | PDF | N/A | Rapid identification of African swine fever virus in diagnostic samples using CRISPR-Cas | | 从不同环境中分离自蟑螂（德国小蠊）的大肠杆菌的抗菌素耐药性、致病性和毒力模式：一个公共卫生问题 | Sigma, S. H. | PDF | N/A | Antimicrobial resistance, pathogenicity and virulence patterns of Escherichia coli isolated from cockroaches (Blattella germanica) across diverse environments: a public health concern | | GnT基序：长度大于或等于8个碱基对的短核苷酸序列，在细菌中能够使T-G:C突变率提高超过1000倍。 | Horton, J. S. | PDF | N/A | GnT motifs: short nucleotide tracts of greater than or equal to 8bp that can increase T-G:C mutation rates >1000-fold in bacteria | | 非孟德尔染色体传递和不寻常的性别决定是否会影响蝇类Bradysia coprophila中的雄性择偶行为？ | Hodson, C. N. | PDF | N/A | Does non-Mendelian chromosome transmission and unusual sex determination affect male mate choice in the fly Bradysia coprophila? | | 野外种群反应规范预测中的变量误差与验证问题 | Ergon, R. | PDF | N/A | Errors-in-variables and validation problems in reaction norm predictions for wild populations | | MicroRNA分析揭示了成年果蝇肠道干细胞功能的新型调控因子。 | Sreejith, P. | PDF | N/A | MicroRNA profiling identifies novel regulators of stem cell function in the adult Drosophila intestine. | | 靶向GSK-β的肽类抑制剂：阿尔茨海默病干预的合理计算策略 | Zareei, S. | PDF | N/A | Targeting GSK-beta with Peptide Inhibitors: A Rational Computational Strategy for Alzheimer's Disease Intervention | | YnaI展示了小电导机械敏感通道中结构门控机制的多样性。 | Flegler, V. J. | PDF | N/A | YnaI exemplifies the diversity of structural gating mechanisms in mechanosensitive channels of small conductance | | 探索合成数据生成在髓母细胞瘤亚组边界研究中的应用 | Prol-Castelo, G. | PDF | N/A | Exploring the Boundaries of Medulloblastoma Subgroups with Synthetic Data Generation | | 基于图网络的疾病-基因-药物关联分析：零样本疾病-药物预测及分析策略 | Liu, Y. | PDF | N/A | Graph Network-Based Analysis of Disease-Gene-Drug Associations: Zero-Shot Disease-Drug Prediction and Analysis Strategies | | 单细胞分析揭示了乙型肝炎病毒阳性（HBV-positive）与乙型肝炎病毒阴性（HBV-negative）肝细胞癌（HCC）病例中不同的免疫特征。 | Liu, K. | PDF | N/A | Single-cell analysis reveals distinct immune characteristics of hepatocellular carcinoma in HBV-positive versus HBV-negative cases | | 人类胰岛素降解酶构象动力学的表征与调控以控制酶活性 | Mancl, J. M. | PDF | N/A | Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity | | 评估过表达Ld_ζ1结构域的多诺瓦利什曼原虫活体在实验性人类内脏利什曼病中的免疫药理学保护效果 | Bansal, R. | PDF | N/A | Evaluation of Immunopharmacological Efficacy of Live Leishmania donovani Overexpressing Ld_ζ1domain for Protection Against Experimental Human Visceral Leishmaniasis | | CCT-217：一种具有里程碑意义的基因沉默疗法，用于减肥，通过促进脂肪褐变，增强瘦体重比例，减少内脏和皮下脂肪，并恢复肥胖患者的代谢健康。 | Reddy, R. | PDF | N/A | CCT-217: A Landmark Gene Silencing Therapeutic for Weight Loss That Enhances Lean Mass Composition, Reduces Visceral, Subcutaneous Fat and Restores Metabolic Health in Obesity through Browning | | 全面评估模拟禁食饮食：唾液代谢物谱、体重减轻及生物标志物分析 | Hof, K. S. | PDF | N/A | Comprehensive Assessment of a Fasting-Mimicking Diet: Salivary Metabolite Profiles, Weight Loss, and Biomarker Analysis | | 将致癌信号重定向至RNA载体复制以治疗转移性癌症 | Lin, M. Z. | PDF | N/A | Rewiring oncogenic signaling to RNA vector replication for the treatment of metastatic cancer | | 奖励与惩罚敏感性的可分离神经功能和分子特征 | Xu, T. | PDF | N/A | Dissociable neurofunctional and molecular characterizations of reward and punishment sensitivity | | 乳腺癌重塑前哨淋巴结中的淋巴管 | Eichin, D. | PDF | N/A | Breast Cancer Remodels Lymphatics in Sentinel Lymph Nodes | | 转录动态揭示BNIP3在果蝇肌肉重塑过程中线粒体自噬的作用
在这项研究中，我们通过转录组分析揭示了BNIP3在果蝇肌肉重塑过程中在线粒体自噬（mitophagy）中的关键作用。BNIP3是一种已知的线粒体自噬相关蛋白，其在肌肉组织中的表达动态变化与线粒体质量控制密切相关。我们的研究发现，在肌肉重塑的不同阶段，BNIP3的转录水平显著波动，表明其在调控线粒体清除和细胞代谢平衡中扮演重要角色。进一步的功能实验证实，BNIP3的缺失会导致线粒体自噬受损，进而影响肌肉组织的正常重塑过程。这些发现为理解肌肉重塑中的分子机制提供了新的见解，并强调了BNIP3在这一过程中的重要性。 | Taoka, H. | PDF | N/A | Transcriptional Dynamics Uncover the Role of BNIP3 in Mitophagy during Muscle Remodeling in Drosophila | | 胞质羧肽酶5（Cytosolic Carboxypeptidase 5）维持哺乳动物室管膜细胞的多纤毛，以确保大脑的正常稳态和功能。 | Dad, R. | PDF | N/A | Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain | | 丘脑前室旁核中表达D2的神经元调节习得的厌恶和安全显著性 | Miranda, M. | PDF | N/A | D2-expressing neurons of the anterior paraventricular nucleus of the thalamus modulate learned aversive and safety salience | | 利用乳清蛋白衍生肽对阿尔茨海默病中成对螺旋丝（PHFs）组装的计算机模拟破坏研究 | Pourmand, S. | PDF | N/A | Computational Disruption of Paired Helical Filaments (PHFs) Assembly Using Milk Lactalbumin-derived Peptides Against Alzheimer's Disease | | 一种可光切换的HaloTag，用于在活细胞中实现荧光的时空控制。 | Walterspiel, F. | PDF | N/A | A photoswitchable HaloTag for spatiotemporal control of fluorescence in living cells | | 人类XPR1磷酸盐输出的结构基础 | Wang, Y. | PDF | N/A | Structural basis of phosphate export by human XPR1 | | 理性设计不饱和硫醚可电离脂质以增强体内mRNA递送 | Samaridou, E. | PDF | N/A | Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In vivo mRNA Delivery | | 使用人工智能预测非编码RNA的功能 | Correia, D. C. | PDF | N/A | Predicting non-coding RNA function using Artificial Intelligence | | 同一菌株，两个基因组：在构建Myxococcus xanthus DZ2的共识环状基因组过程中，揭示了近缘粘细菌菌株间大型多倍体前噬菌体区域的多样性。 | Sharma, G. | PDF | N/A | Same strain, two genomes: Creating a consensus circular genome of Myxococcus xanthus DZ2 revealed the diversity of a large polyploid prophage region within the close-related myxobacterial strains | | 长期免疫变化在COVID-19后的表现，以及卡介苗接种和潜伏感染对疾病严重程度的影响 | Bendickova, K. | PDF | N/A | Long-term immune changes after COVID-19 and the effect of BCG vaccination and latent infections on disease severity | | 抑制PCBP1通过调节TAK1增强PPARγ，以改善妊娠糖尿病中的血糖和脂质代谢紊乱 | Xia, X. | PDF | N/A | Suppression of PCBP1 Enhances PPARgamma via TAK1 Modulation to Improve Glycemic and Lipid Metabolism Disorders in Gestational Diabetes Mellitus | | 蚯蚓（Eisenia andrei）在暴露于草甘膦污染的杂草堆肥中的行为与存活研究 | Ortiz-Ceballos, G. C. | PDF | N/A | Behavior and survival of earthworm (Eisenia andrei) to exposure to glyphosate-contaminated weed compost | | 缓慢的空间迁移有助于在时变环境中消除合作性抗菌素耐药性。 | Hernandez-Navarro, L. | PDF | N/A | Slow spatial migration can help eradicate cooperative antimicrobial resistance in time-varying environments | | MECOM通过抑制CEBPA表达来阻止细胞分化，从而驱动侵袭性白血病的发生。 | Fleming, T. J. | PDF | N/A | CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias | | 上下文依赖的PSIICOS：一种考虑任务相关功率泄漏的功能连接性估计新框架 | Kleeva, D. | PDF | N/A | Context-Dependent PSIICOS: A Novel Framework for Functional Connectivity Estimation Accounting for Task-Related Power Leakage | | 星形胶质细胞来源的细胞外基质蛋白在应激诱导的抑郁症中调节突触重塑。 | Zhang, R. | PDF | N/A | Astrocyte-derived extracellular matrix proteins regulate synapse remodeling in stress-induced depression | | 如何处理黑暗：对数尺度上零膨胀个人光照暴露数据的建模与可视化 | Zauner, J. | PDF | N/A | How to deal with darkness: Modeling and visualization of zero-inflated personal light exposure data on a logarithmic scale | | 大脑表面深处的回旋：重现一项历史报告，该报告将“桥接”的中央沟与额顶叶中部的pli de passage（额顶叶中间通道）相关联。 | Schweizer, R. | PDF | N/A | The deep winding at the brain surface: replicating a historical report associating the 'bridged' central sulcus with the pli de passage fronto-parietal moyen | | 测量到的表征距离何时能够反映神经表征的几何结构？ | Bossio Botero, V. | PDF | N/A | When do measured representational distances reflect the neural representational geometry? | | 在鸣禽学习过程的强化学习模型中，权重转移的作用 | Tran, K. | PDF | N/A | Weight Transfer in the Reinforcement Learning Model of Songbird Acquisition | | 卡泊芬净与铁结合会降低其对白色念珠菌的抗真菌效果。 | Pedras, A. | PDF | N/A | Caspofungin binding to iron compromises its antifungal efficacy against Candida albicans | | 硫化氢（H2S）通过协调氧化还原平衡、碳代谢和线粒体生物能量学来抑制SARS-CoV-2病毒感染。 | Agrawal, R. | PDF | N/A | Hydrogen sulfide (H2S) coordinates redox balance, carbon metabolism, and mitochondrial bioenergetics to suppress SARS-CoV-2 infection. | | 在大鼠以中等速度和快速小跑时进行主动水平扰动期间的肢体负荷控制 | Andrada, E. | PDF | N/A | Control of limb loading during active horizontal perturbations at moderate and fast trots in rats | | 微管上动力蛋白运输机器组装的分子基础 | Rao, Q. | PDF | N/A | Molecular basis for the assembly of the dynein transport machinery on microtubules | | 以下是这段文字的中文翻译：
LC-MS/MS 表征 SOBERANA(R)02，一种针对 SARS-CoV-2 的受体结合域-破伤风类毒素结合疫苗
翻译说明： - LC-MS/MS：液相色谱-串联质谱法，是一种用于分析复杂混合物的技术。 - SOBERANA(R)02：疫苗名称，保留原文。 - receptor binding domain-tetanus toxoid conjugate vaccine：受体结合域-破伤风类毒素结合疫苗，描述了疫苗的组成和作用机制。 - against SARS-CoV-2：针对 SARS-CoV-2，说明了疫苗的目标病毒。
希望这个翻译对您有帮助！ | Martinez, O. | PDF | N/A | LC-MS/MS characterization of SOBERANA(R)02, a receptor binding domain-tetanus toxoid conjugate vaccine against SARS-CoV-2 | | 核苷酸编码调控着Lis1解除动力蛋白自抑制的能力。 | Geohring, I. C. | PDF | N/A | A nucleotide code governs Lis1's ability to relieve dynein autoinhibition | | Nde1促进Lis1与全长自抑制状态的人源Dynein-1的结合 | Yang, J. | PDF | N/A | Nde1 Promotes Lis1 Binding to Full-Length Autoinhibited Human Dynein-1 | | 通过尿液蛋白质组探索二甲双胍对人体的影响 | Chen, Y. | PDF | N/A | Exploring the effects of metformin on the body by urine proteome | | 有效马尔可夫动力学方法解决随机基因表达的非马尔可夫动力学 | Li, Y. | PDF | N/A | Effective Markovian dynamics method of solving non-Markovian dynamics of stochastic gene expression | | RhoBAST RNA适配体实现环开启荧光的结构基础。 | Siwik, S. H. | PDF | N/A | Structural basis for ring-opening fluorescence by the RhoBAST RNA aptamer. | | 推断病毒准种的方法：个体样本比较分析。 | Gregori, J. | PDF | N/A | Inference with Viral Quasispecies. Methods for Individual Samples Comparative Analysis. | | TCPGdb：一个全面的T细胞扰动基因组学数据库，用于识别关键的T细胞调控因子 | Dong, C. | PDF | N/A | TCPGdb: A comprehensive T cell perturbation genomics database for identification of critical T cell regulators | | 局部应力与长程应力在果蝇胚胎头沟形成中的作用 | Niloy, R. A. | PDF | N/A | The role of local and long-range stresses in cephalic furrow formation in the Drosophila melanogaster embryo | | 用于评估合成基因电路的线性混合效应模型 | Partipilo, G. | PDF | N/A | A Linear Mixed Effects Model for Evaluating Synthetic Gene Circuits | | 神经退行性和神经发育性作用：大分子脂质转运蛋白VPS13A和BLTP2在运动障碍中的角色 | Neuman, S. D. | PDF | N/A | Neurodegenerative and neurodevelopmental roles for bulk lipid transporters VPS13A and BLTP2 in movement disorders | | 在最近出现的携带NSP6中L260F突变的SARS-CoV-2变体中，RNA复制和致病性得到了增强。 | Taha, T. Y. | PDF | N/A | Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6 | | 深度学习模型用于从微CT成像中精确分割果蝇大脑
在这项研究中，我们开发了一种基于深度学习的模型，专门用于从微CT（计算机断层扫描）成像数据中精确分割果蝇（Drosophila melanogaster）的大脑。该模型结合了先进的卷积神经网络（CNN）架构，能够高效地处理三维图像数据，并准确地识别和分割出果蝇大脑的复杂结构。通过大量的训练数据和优化算法，我们的模型在多个评估指标上均表现出色，为神经科学研究提供了一种强大的工具，有助于更深入地理解果蝇大脑的解剖和功能。 | McDaniel, J. F. | PDF | N/A | A Deep Learning Model for Accurate Segmentation of the Drosophila melanogaster Brain from Micro-CT Imaging | | 冷大气等离子体在生物打印的三维肿瘤微环境模型中选择性破坏乳腺癌生长 | Bouret, L. M. | PDF | N/A | Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor Microenvironment Model |