| 匹罗卡品诱导的癫痫持续状态后，星形胶质细胞中持续的DNA甲基化和稳态基因的下调：对癫痫发生的影响 |
Gomez Cuautle, D. D. |
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Persistent DNA methylation and downregulation of homeostatic genes in astrocytes after pilocarpine-induced status epilepticus: Implications for epileptogenesis |
| CD44和Ezrin通过限制表皮生长因子受体（EGF受体）的流动性，生成了一种新的细胞骨架信号模块的空间排列，从而驱动基于膜泡（bleb）的细胞迁移。 |
Jha, A. |
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CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration |
| Empathi：基于嵌入的噬菌体蛋白质注释工具，通过分层分配实现 |
Boulay, A. |
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Empathi: Embedding-based Phage Protein Annotation Tool by Hierarchical Assignment |
| YX0798 是一种高效、选择性且口服有效的 CDK9 抑制剂，用于治疗侵袭性淋巴瘤。 |
Jiang, V. |
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YX0798 Is a Highly Potent, Selective, and Orally Effective CDK9 Inhibitor for Treating Aggressive Lymphoma |
| Tetralone-ABA 能够增强葡萄藤（包括欧洲葡萄 V. vinifera 和杂交葡萄 V. hybrid）的冬季抗寒能力，减少其脱锻炼过程，并延迟芽的萌发。 |
Wang, H. |
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Tetralone-ABA enhances winter cold acclimation, reduces deacclimation, and delays budbreak in V. vinifera and V. hybrid grapevines |
| 人类趋避冲突的电路动力学 |
Staveland, B. R. |
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Circuit dynamics of approach-avoidance conflict in humans |
| 通过使用新表位抗体P90对HD（亨廷顿病）人类和小鼠脑组织进行Western blot和免疫染色检测HTTex1p，揭示了CAG重复扩增对其大小、溶解性以及对MSH3沉默反应的影响。 |
Sapp, E. |
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Detection of HTTex1p by western blot and immunostaining of HD human and mouse brain using neo-epitope antibody P90 highlights impact of CAG repeat expansion on its size, solubility, and response to MSH3 silencing |
| 大脑语言激活及其与认知和语言测量指标的关系 |
Balboni, I. |
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Brain activation for language and its relationship to cognitive and linguistic measures |
| 不同的机制将驱动蛋白功能的获得与丧失与轴突变性联系起来。 |
Liew, Y.-T. |
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Different mechanisms link gain and loss of kinesin functions to axonal degeneration |
| 在阿尔茨海默病神经病理学发病时，对人类内嗅皮层进行细胞类型特异性分析 |
Rodriguez-Rodriguez, P. |
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Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer's disease neuropathology |
| 小鼠初级视觉皮层对冲突性双眼刺激的皮质反应 |
Montgomery, D. P. |
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Cortical responses to conflicting binocular stimuli in mouse primary visual cortex |
| 神经生长因子信号调节轴突维持蛋白的丰度及沃勒变性的动力学 |
Danos, J. A. |
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Nerve Growth Factor Signaling Tunes Axon Maintenance Protein Abundance and Kinetics of Wallerian Degeneration |
| Nurr1调控屏状核的发育与功能 |
Yan, K. |
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Nurr1 orchestrates claustrum development and functionality |
| 极低水活性条件下的生命极限：太阳能盐场（智利阿塔卡马盐沼）中的锂浓度池 |
Demergasso, C. |
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The limit of life at extremely low water activity:Lithium-concentration ponds in a solar saltern(Salar de Atacama, Chile) |
| ZapA采用双重机制来促进大肠杆菌中Z环的形成。 |
Cui, Y. |
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ZapA employs a two-pronged mechanism to facilitate Z ring formation in Escherichia coli |
| 在生长中的神经元中，CoREST-2和RE-1对H3K9me2异染色质的动态平衡调控 |
Drube, J. F. |
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Dynamic balance of H3K9me2 heterochromatin by CoREST-2 and RE-1 in growing neurons |
| Argonaute蛋白调控精子生成转录程序的时间进程。 |
Carro, M. d. l. M. |
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Argonaute proteins regulate the timing of the spermatogenic transcriptional program |
| 单细胞和空间转录组学揭示了B染色体在驱动植物入侵性中的作用 |
Wang, C. |
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Single-cell and spatial transcriptomics uncover the role of B chromosomes in driving plant invasiveness |
| 40S核糖体亚基通过一维扩散在mRNA上扫描寻找起始密码子。 |
Wakabayashi, H. |
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40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion |
| 虹膜隐窝可能降低闭角型青光眼的发生风险：一项基于临床和人类虹膜数据的计算生物力学研究 |
Tan, R. K. Y. |
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Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived from Clinical and Human Iris Data |
| 在激光扫描显微镜中通过结构化检测进行波前估计 |
Fersini, F. |
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Wavefront estimation through structured detection in laser scanning microscopy |
| 利用Bambu-Clump从单细胞和空间长读长RNA测序数据中进行异构体水平的发现、定量及融合分析。 |
Sim, A. D. |
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Isoform-level discovery, quantification and fusion analysis from single-cell and spatial long-read RNA-seq data with Bambu-Clump |
| 通过新型染色质相互作用数据标准化方法提升增强子-启动子环的检测 |
Wang, X. |
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Boosting the detection of enhancer-promoter loops via novel normalization methods for chromatin interaction data |
| 微生物通用模型：利用大型语言模型进行情境化微生物组分析 |
Zhang, H. |
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Microbial general model: Leveraging large language model for contextualized microbiome analysis |
| 代表性荧光蛋白中双光子吸收的方向性 |
Lazar, J. |
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Directionality of two-photon absorption in representative fluorescent proteins |
| 离散免疫抑制屏障的获得促进了从癌前病变到浸润性人类肺癌的起始和进展。 |
Yoffe, L. |
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Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer. |
| MaiZaic：一个强大的端到端流程，用于拼接自由飞行的农业领域航拍视频 |
Kharismawati, D. E. |
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MaiZaic: a robust end-to-end pipeline for mosaicking freely flown aerial video of agricultural fields |
| 在神经元发育过程中，长时间尺度上的旋转稳定动力学逐渐显现。 |
Burrows, D. R. |
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Rotationally Stable Dynamics Over Long Timescales Emerge in Neuronal Development |
| 在结直肠癌的侵袭性生物膜中，核梭杆菌（Fusobacterium nucleatum）的含量显著增加。 |
Queen, J. |
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Fusobacterium nucleatum is enriched in invasive biofilms in colorectal cancer |
| 单核RNA测序揭示了死后间隔时间对小鼠大脑细胞组成和基因表达分析的影响。 |
yunxia, G. |
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Single-nucleus RNA sequencing revealed the impact of post-mortem interval on the cellular component and gene expression analysis of mouse brains |
| 无交联剂的原位水凝胶诱导人牙髓干细胞自聚集，并增强其抗菌活性。 |
Lee, S. J. |
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Crosslinker-free in situ hydrogel induces self-aggregation of human dental pulp stem cells with enhanced antibacterial activity |
| 当代HIV-1 C亚型在不同区域表现出独特的中和特性，针对最优秀的广谱中和抗体。 |
Sutar, J. |
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Distinct region-specific neutralization profiles of contemporary HIV-1 clade C against best-in-class broadly neutralizing antibodies |
| T细胞衍生的IFN-γ在病毒感染期间抑制滤泡辅助性T细胞分化和抗体反应 |
Sala, E. |
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T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses during Viral Infections |
| Clostridium novyi B型在野生亚洲象中引发致命的出血性疾病。 |
Padhi, S. K. |
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Clostridium novyi type B causes fatal hemorrhagic disease in wild Asian elephants |
| 先前感染传染性法氏囊病病毒（IBDV）延长了某些鸡只从口咽腔排出野鸭H3N8甲型流感病毒（IAV）的时间，并增加了IAV样本中氨基酸替换的数量。 |
Nazki, S. |
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Prior infection with IBDV prolonged the shedding of a mallard H3N8 influenza A virus (IAV) challenge from the oropharyngeal cavity of some chickens and increased the number of amino acid substitutions in the IAV samples |
| SerRS通过液-液相分离（LLPS）被隔离，影响了局部翻译过程，并导致抗生素持久性的形成。 |
Zhang, Z. |
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Sequestration of SerRS through LLPS Impairs Localized Translation and Contributes to Antibiotic Persistence |
| 回顾过往：先前的捕食风险经历并不决定群体中个体的反捕食反应 |
Rawat, K. |
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Peers over the past: Prior predation-risk experience does not dictate antipredator responses of individuals in groups |
| 《埃塞俄比亚西北部南贡德尔地区食用大麦（Hordeum vulgare L.）的适应性与产量稳定性分析》 |
Worku, A. A. |
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Adaptability and yield stability analysis of food barley (Hordeum vulgare L.) in South Gondar zone, Northwest Ethiopia |
| 五个模式物种中端粒到端粒基因组的填充区域基因组特征 |
Xiong, C. |
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Genomic feature of filled regions of telomere-to-telomere genomes in five model species |
| 26S蛋白酶体中USP14调控底物降解的动力学模型 |
Wu, D. |
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A kinetic model for USP14 regulated substrate degradation in 26S proteasome |
| 黄病毒劫持HuR以抑制CNPY3：免疫逃逸与治疗干预的新途径 |
Ding, X. |
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Flaviviruses Hijack HuR to Suppress CNPY3: A Novel Pathway for Immune Evasion and Therapeutic Intervention |
| 一种含有从牛初乳中纯化的分泌组的新产品，Purasomes IRC100+，用于治疗阴道萎缩：体外研究评估其安全性和有效性 |
Salvaggio, A. |
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A new product containing secretome purified from bovine colostrum, Purasomes IRC100+, in the treatment of vaginal atrophy: in vitro study to evaluate safety and effectiveness |
| BORC通过马达蛋白UNC-104/KIF1A和UNC-116/KIF5来分离突触小泡和溶酶体蛋白。 |
Mathew, A. |
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BORC segregates synaptic vesicle and lysosomal proteins through motors UNC-104/KIF1A and UNC-116/KIF5 |
| 变暖增加了真核寄生浮游生物的丰富度并塑造了其群落结构 |
Rajarajan, A. |
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Warming increases richness and shapes assemblages of eukaryotic parasitic plankton |
| 第三种类型的PETase来自海洋的Halopseudomonas谱系。 |
Turak, O. |
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A third type of PETase from the marine Halopseudomonas lineage |
| 肽盘辅助的疏水聚类技术用于生产多聚体和多特异性纳米抗体蛋白 |
Duong, F. |
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Peptidisc-assisted hydrophobic clustering towards the production of multimeric and multispecific nanobody proteins |
| 非核小体的 (CENP-A/H4)2 - DNA 复合物可能作为着丝粒组织的一个平台 |
Ali-Ahmad, A. |
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Non-nucleosomal (CENP-A/H4)2 - DNA complexes as a possible platform for centromere organization |
| 通过人工智能驱动的迭代学习在蛋白质序列空间中进行高效搜索 |
Sanchez-Ruiz, J. |
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Efficient searches in protein sequence space through AI-driven iterative learning |
| 非稀释结合理论及表面相分离在膜结合蛋白中的应用 |
Zhao, X. |
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Theory of non-dilute binding and surface phase separation applied to membrane-binding proteins |
| 成熟的套索肽通过广泛存在的乙酰转移酶进行迭代酰化，以生产脂质套索肽。 |
Xiong, J. |
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Iterative acylation on mature lasso peptides by widespread acetyltransferases for lipolasso production |
| 持久性烈性噬菌体存在于细菌分离物中。 |
Dougherty, P. E. |
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Persistent virulent phages exist in bacterial isolates |
| 脂质组学揭示多能干细胞向神经和中胚层谱系分化过程中的细胞特异性变化 |
Odenkirk, M. T. |
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Lipidomics Reveals Cell Specific Changes During Pluripotent Differentiation to Neural and Mesodermal Lineages |
| 发育中的突触修剪在小脑橄榄核环路中塑造预测性处理 |
Verma, S. |
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Developmental synaptic pruning in the olivo-cerebellar circuit sculpts predictive processing |
| 婴儿早期的听觉通路成熟：与言语产生的关联 |
Liu, F. |
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Auditory tract maturation in early infancy: Links to speech production |
| GPNMB 是溶酶体功能障碍的生物标志物，并通过 LRRK2 调控的溶酶体胞吐作用分泌。 |
Bogacki, E. C. |
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GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis |
| 乙醇通过增加颅神经嵴细胞的凋亡，在Bmp突变体中诱导颅面缺陷，这一过程独立于nkx2.3的作用。 |
Vo, H. D. L. |
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Ethanol induces craniofacial defects in Bmp mutants independent of nkx2.3 by elevating cranial neural crest cell apoptosis |
| 意外的D-统计量转向：为何应用于人类的D-统计量测量的是突变率变异而非尼安德特人基因渗入 |
Amos, W. |
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Unexpected D-tour Ahead: Why the D-Statistic, applied to Humans, Measures Mutation Rate Variation not Neanderthal Introgression |