BioRxiv 2025-01-09 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 进化在于细节：现代人类与尼安德特人的调控差异 | Barker, H. | N/A | Evolution is in the details: Regulatory differences in modern human and Neanderthal | |
| SATB1通过与碱基非配对区域（BURs）结合来组织基因组，为SATB1调控的基因表达提供了支架。 | Kohwi, Y. | N/A | Genome organization by SATB1 binding to base-unpairing regions (BURs) provides scaffold for SATB1-regulated gene expression | |
| 陆禽性别二色性演化的大规模辐射研究：重新审视华莱士模型中偏向雌性的选择机制 | Li, Z. | N/A | The evolution of sexual dichromatism in a large radiation of landfowl: Re-examining female-biased selection in Wallace's model | |
| RAD51C在高尔基体和细胞核之间的时空动态调控同源重组和基因组稳定性。 | Galea, G. | N/A | Spatiotemporal dynamics of RAD51C between the Golgi and nucleus regulates homologous recombination and genomic stability. | |
| 基于相互作用的神经群体的生物合理性决策模型 | Baspinar, E. | N/A | A biologically plausible decision-making model based on interacting neural populations | |
| 通过数百万次实验室检测揭示的孕期和产后动态 | Bar, A. | N/A | Pregnancy and postpartum dynamics revealed by millions of lab tests | |
| 以下是将这段英文翻译成中文的结果： |
证据表明，合成的自体四倍体秀丽隐杆线虫（Caenorhabditis elegans）因多倍性而增强了抗逆性。
翻译说明： - "Evidence for" 翻译为“证据表明”。 - "increased stress resistance" 翻译为“增强了抗逆性”。 - "due to polyploidy" 翻译为“因多倍性”。 - "synthetic autotetraploid" 翻译为“合成的自体四倍体”。 - "Caenorhabditis elegans" 是模式生物，通常保留其拉丁学名，中文名称为“秀丽隐杆线虫”。 | Chauve, L. | PDF | N/A | Evidence for increased stress resistance due to polyploidy from synthetic autotetraploid Caenorhabditis elegans | | 沉浸式集体觅食中社会和独立学习适应机制 | Wu, C. M. | PDF | N/A | Adaptive mechanisms of social and asocial learning in immersive collective foraging | | 光遗传学控制RhoA的GEF揭示了一个从收缩到突起的信号转换机制 | de Seze, J. | PDF | N/A | Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion | | 实验设计影响Ornithodoros蜱对非洲猪瘟病毒的媒介能力：已发表评估的荟萃分析 | Bernard, J. | PDF | N/A | Experimental design impacts the vector competence of Ornithodoros ticks for African swine fever virus: a meta-analysis of published evaluations | | 斑马鱼定向和防御反应的血清素能调节 | do Nascimento, B. G. | PDF | N/A | Serotonergic mediation of orienting and defensive responses in zebrafish | | 评估环境干扰和农药混合物对氮循环相关土壤微生物指标的影响 | Drocco, C. | PDF | N/A | Evaluating the Effects of Environmental Disturbances and Pesticide Mixtures on N-cycle related Soil Microbial Endpoints | | 爆炸效应蛋白Pwl2是一种毒力因子，它通过改变宿主蛋白HIPP43的细胞定位来抑制免疫反应。 | Were, V. | PDF | N/A | The blast effector Pwl2 is a virulence factor that modifies the cellular localisation of host protein HIPP43 to suppress immunity. | | 利用药物调节的分子连接性绘制血清素动态图 | Ionescu, T. M. | PDF | N/A | Mapping Serotonergic Dynamics using Drug-Modulated Molecular Connectivity | | 随机性细胞内在干细胞决策控制涡虫中集落的生长 | Frankovits, T. | PDF | N/A | Stochastic cell-intrinsic stem cell decisions control colony growth in planarians | | 人类和小鼠神经祖细胞命运特化中纤毛过渡区蛋白的差异性需求 | Wiegering, A. | PDF | N/A | A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification | | 组蛋白伴侣Spn1在启动子处保护染色质，并在开放阅读框中维持核小体定位 | Tonsager, A. J. | PDF | N/A | The Histone Chaperone Spn1 Preserves Chromatin Protections at Promoters and Nucleosome Positioning in Open Reading Frames | | 大脑中双向网络核心与感知意识和认知的关联 | Taguchi, T. | PDF | N/A | Association of bidirectional network cores in the brain with perceptual awareness and cognition | | 生态因素而非社会因素解释了头足类动物大脑大小的差异。 | Basava, K. | PDF | N/A | Ecological not social factors explain brain size in cephalopods | | 对13种突变特征归因工具进行基准测试，其中包括一种新的改进算法 | Jiang, N. | PDF | N/A | Benchmarking 13 tools for mutational signature attribution, including a new and improved algorithm | | DeMBA：一个用于在空间和时间中导航小鼠大脑的发展图谱 | Carey, H. | PDF | N/A | DeMBA: a developmental atlas for navigating the mouse brain in space and time | | 树群落的多维结构承载着宿主-寄生蜂网络及其系统发育组成 | Wang, M.-Q. | PDF | N/A | Multi-dimensionality of tree communities structure host-parasitoid networks and their phylogenetic composition | | STAT3-VDAC1轴调节线粒体功能并在急性髓性白血病细胞存活中起关键作用 | Gil, K. B. | PDF | N/A | The STAT3-VDAC1 Axis Modulates Mitochondrial Function and Plays a Critical Role in the Survival of Acute Myeloid Leukemia Cells | | DNA中的N6-甲基腺苷促进基因组稳定性 | Conti, B. | PDF | N/A | N6-methyladenosine in DNA promotes genome stability | | 通过卡尔曼滤波提高全身质心位置的准确性 | Le Mouel, C. | PDF | N/A | Improved accuracy of the whole body Center of Mass position through Kalman filtering | | 分子系统发育学揭示了澳大利亚洞穴蟋蟀（直翅目：Rhaphidophoridae）的进化历史和隐藏多样性 | Beasley-Hall, P. G. | PDF | N/A | Molecular phylogenetics illuminates the evolutionary history and hidden diversity of Australian cave crickets (Orthoptera: Rhaphidophoridae) | | Shank3小鼠中与年龄相关的皮质过度连接在麻醉状态下得到逆转 | Montagni, E. | PDF | N/A | Age-Dependent Cortical Overconnectivity in Shank3 Mice is Reversed by Anesthesia | | wtf杀手减数分裂驱动因子的功能限制 | Srinivasa, A. N. | PDF | N/A | Functional constraints of wtf killer meiotic drivers | | β-连环蛋白在栉水母Mnemiopsis leidyi中的定位表明其在细胞粘附和核功能中的祖先作用 | Walters, B. M. | PDF | N/A | β-catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function | | 绵羊双心室心力衰竭中的三尖瓣瓣叶重塑：瓣叶之间的比较 | Kostelnik, C. J. | PDF | N/A | Tricuspid valve leaflet remodeling in sheep with biventricular heart failure: A comparison between leaflets | | 强迫症SAPAP3小鼠模型的病前特征：行为、神经可塑性和裸盖菇素治疗 | Lazar, M. | PDF | N/A | Premorbid Characteristics of the SAPAP3-Mouse Model of Obsessive-Compulsive Disorder: Behavior, Neuroplasticity, and Psilocybin Treatment | | habtools: 一个用于计算表面和物体三维指标的R包 | Schiettekatte, N. M. | PDF | N/A | habtools: an R package to calculate 3D metrics for surfaces and objects | | 传粉者访问模式和不同的生殖相容性导致了印度西高止山脉一种夜间姜科植物中不同形态的不均等丰度。 | Shrotri, S. | PDF | N/A | Pollinator visitation pattern and differential reproductive compatibilities contribute to the unequal morph abundances in a nocturnal ginger from Western Ghats, India | | 个体特定策略指导类别学习 | Collina, J. | PDF | N/A | Individual-specific strategies inform category learning | | 适应性而非预测性驱动哺乳动物感觉皮层中的神经元放电反应 | Westerberg, J. A. | PDF | N/A | Adaptation, not prediction, drives neuronal spiking responses in mammalian sensory cortex | | 突变体可以增加硝基呋喃妥因耐药性突变的发生率和特异性。 | Kettlewell, R. | PDF | N/A | Mutators can increase both the rate of occurrence and specificity of nitrofurantoin resistance mutations | | FtsK对于无FtsZ的沙眼衣原体独特分裂体复合物的组装至关重要 | Harpring, M. | PDF | N/A | FtsK is Critical for the Assembly of the Unique Divisome Complex of the FtsZ-less Chlamydia trachomatis | | 优化寄生线虫的单核分离和RNA测序 | Buddenborg, S. K. | PDF | N/A | Optimisation of single-nuclei isolation and RNA sequencing of parasitic nematodes | | 脂质包装缺陷是α-突触核蛋白膜结合的必要和充分条件 | Johnson, D. H. | PDF | N/A | Lipid Packing Defects are Necessary and Sufficient for Membrane Binding of alpha-Synuclein | | 在问题解决过程中，眼与手的协同动作揭示了层次化的计划组织。 | Eluchans, M. | PDF | N/A | Eye and hand coarticulation during problem solving reveals hierarchically organized planning | | 在妊娠首三个月期间人类心脏图谱的多模态精细化 | De Bono, C. | PDF | N/A | Multi-modal refinement of the human heart atlas during the first gestational trimester | | 在复杂的生态系统动态中，结构化和随机性相互作用交织在一起。 | Giral Martinez, J. | PDF | N/A | Structured and random interactions interplay in complex ecosystems dynamics | | 结构上不同的锰感应核糖开关适体调节多种表达平台架构。 | Stephen, C. | PDF | N/A | Structurally distinct manganese-sensing riboswitch aptamers regulate diverse expression platform architectures | | 无需生态位指导、反馈或微调的自我更新 | MacArthur, B. | PDF | N/A | Self-renewal without niche instruction, feedback or fine-tuning | | 以下是这段英文的中文翻译：
蛋白质序列的固有无序特征的概率注释
翻译说明： - "Probabilistic" 翻译为“概率的”，表示基于概率的预测或注释。 - "Annotations" 翻译为“注释”，指对序列特征的解释或标记。 - "Protein Sequences" 翻译为“蛋白质序列”，即蛋白质的氨基酸排列顺序。 - "Intrinsically Disordered Features" 翻译为“固有无序特征”，指蛋白质序列中缺乏固定三维结构的部分。
整体翻译为“蛋白质序列的固有无序特征的概率注释”，表示通过概率方法对蛋白质序列中可能存在的无序区域进行预测或标记。 | Malhis, N. | PDF | N/A | Probabilistic Annotations of Protein Sequences for Intrinsically Disordered Features | | 遗传和行为分析表明，铜绿蝇（Lucilia cuprina）的幼虫和成虫阶段利用不同的感觉系统来检测腐烂的牛肉。 | Wulff, J. P. | PDF | N/A | Genetic and behavioral analyses suggest that larval and adult stages of Lucilia cuprina employ different sensory systems to detect rotten beef | | 墨西哥丽脂鲤地表鱼和洞穴鱼性腺中性别调控基因的差异表达 | Webster, K. A. | PDF | N/A | Differential expression of sex regulatory genes in gonads of Astyanax mexicanus surface fish and cavefish | | 以下是这段文字的中文翻译：
基于无标记多模态非线性光学成像的前列腺导管内癌的纹理分析分类
翻译说明： - "Texture-Analysis Classification" 翻译为 "纹理分析分类"，指的是通过分析图像纹理特征进行分类的方法。 - "Intraductal Carcinoma of the Prostate" 翻译为 "前列腺导管内癌"，是一种前列腺癌的亚型。 - "Label-Free" 翻译为 "无标记"，表示无需使用染色或标记物。 - "Multimodal Nonlinear Optical Imaging" 翻译为 "多模态非线性光学成像"，是一种结合多种非线性光学技术的成像方法。
希望这段翻译对你有帮助！如果有其他问题，欢迎随时提问。 | Gagnon, J. R. | PDF | N/A | Texture-Analysis Classification of Intraductal Carcinoma of the Prostate Using Label-Free Multimodal Nonlinear Optical Imaging | | 中更新世过渡期间东地中海远洋生态系统对海水条件变化的响应 | Agiadi, K. | PDF | N/A | Pelagic ecosystem responses to changes in seawater conditions during the Middle Pleistocene Transition in the Eastern Mediterranean | | CLCNet：一种用于植物基因组预测的对比学习与染色体感知网络 | Huang, J. | PDF | N/A | CLCNet: a contrastive learning and chromosome-aware network for genomic prediction in plants | | 病毒准种推断。个体样本比较分析方法。 | Gregori, J. | PDF | N/A | Inference with Viral Quasispecies. Methods for Individual Samples Comparative Analysis. | | 使用Evolla解码蛋白质的分子语言 | Zhou, X. | PDF | N/A | Decoding the Molecular Language of Proteins with Evolla | | Chiari II型脑畸形是继发于开放性脊柱裂的一种病症。 | Clark, M. | PDF | N/A | Chiari II brain malformation is secondary to open spina bifida | | 更具支配地位的狒狒睡眠时间更少且质量较低。 | Fele, M. | PDF | N/A | More dominant baboons have less and lower quality sleep | | 聚合酶突变是H5N1流感病毒早期适应奶牛及其他哺乳动物的基础。 | Dholakia, V. | PDF | N/A | Polymerase mutations underlie early adaptation of H5N1 influenza virus to dairy cattle and other mammals. | | 人类睡眠纺锤波追踪实验性兴奋的脑回路 | Thom, J. L. | PDF | N/A | Human sleep spindles track experimentally excited brain circuits | | 优化合成囊性纤维化痰液培养基以促进非典型流感嗜血杆菌的生长 | Do Carmo Silva, P. | PDF | N/A | Optimising synthetic cystic fibrosis sputum media for growth of non-typeable Haemophilus influenzae | | LncPTPred：基于交联免疫沉淀（CLIP-Seq）数据预测长链非编码RNA与蛋白质相互作用 | Das, G. | PDF | N/A | LncPTPred: Predicting lncRNA-Protein Interaction based on Crosslinking and Immunoprecipitation (CLIP-Seq) Data | | 低磁场以钟形响应刺激心脏线粒体生物能量学：可能通过自由基对机制 | Beutner, G. | PDF | N/A | Low Magnetic Fields Stimulate Cardiac Mitochondrial Bioenergetics with a Bell-Shaped Response: Possibly Via a Radical Pair Mechanism | | 不同兴奋性输入源的协调增强了小鼠视觉丘脑中的运动选择性 | Fei, Y. | PDF | N/A | Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus | | 铁硫簇蛋白是等离子体处理的大肠杆菌中的薄弱环节。 | Krewing, M. | PDF | N/A | Iron-sulfur cluster proteins present the weak spot in plasma-treated Escherichia coli | | 星舰巨型转座子在真菌植物病原体的塑料基因组区域中占据主导地位，并推动毒力进化 | Sato, Y. | PDF | N/A | Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution | | 墨西哥ToBRFV分离株的宿主特异性适应与全球传播潜力：基因组分析的启示
在这段翻译中，"Host-Specific Adaptations" 指的是病毒或病原体对特定宿主的适应性变化，"Global Transmission Potential" 指的是该病原体在全球范围内传播的可能性。"Mexican ToBRFV Isolate" 指的是在墨西哥分离出的一种ToBRFV（番茄褐色皱果病毒）的样本。"Insights from Genomic Analysis" 表示通过基因组分析获得的深入理解或见解。整体而言，这段文字描述的是通过基因组分析，研究人员对墨西哥ToBRFV分离株的宿主适应性和全球传播潜力有了更深入的理解。 | Macorra, E. J. Z. | PDF | N/A | Host-Specific Adaptations and Global Transmission Potential of a Mexican ToBRFV Isolate: Insights from Genomic Analysis | | NF-κB是缺氧诱导基因表达的核心调控因子 | Shakir, D. | PDF | N/A | NF-κB is a Central Regulator of Hypoxia-Induced Gene Expression | | 基于网络的框架用于研究原发性纤毛病的病因学和表型多样性 | Aarts, E. M. | PDF | N/A | Network-based framework for studying etiology and phenotype diversity in primary ciliopathies | | DHDDS患者细胞中的Niemann-Pick C样内溶酶体功能障碍，这是一种先天性糖基化障碍，可以通过米格鲁司特（miglustat）进行治疗。 | Best, H. L. | PDF | N/A | Niemann-Pick C-like endo-lysosomal dysfunction in DHDDS patient cells, a congenital disorder of glycosylation, can be treated with miglustat | | 长期通过营养缺陷型交叉喂养维持微生物群落稳态 | Grandel, N. E. | PDF | N/A | Long-term homeostasis in microbial consortia via auxotrophic cross-feeding | | 高阶脑电图微状态句法及替代测试 | von Wegner, F. | PDF | N/A | Higher-order EEG microstate syntax and surrogate testing | | 通过竞争性抑制进行整体启动：新皮质柱中感觉上下文存储和偏差检测的局部机制 | Thorpe, R. V. | PDF | N/A | Ensemble priming via competitive inhibition: local mechanisms of sensory context storage and deviance detection in the neocortical column | | 学习诱导的可塑性在记忆回忆过程中降低了皮质印迹细胞树突的兴奋性。 | Rosier, M. | PDF | N/A | Learning-induced plasticity decreases cortical engram cell dendritic excitability during memory recall | | 皮层第5层亚型在联想学习中的不同作用 | Moberg, S. | PDF | N/A | Distinct roles of cortical layer 5 subtypes in associative learning | | 活动依赖的神经元L型钙通道通过CaMKII进行聚类 | Yang, Q. | PDF | N/A | Activity dependent Clustering of Neuronal L-Type Calcium Channels by CaMKII | | 与青少年特质焦虑相关的静息态连接模式 | Baggio, T. | PDF | N/A | Resting State connectivity patterns associated with trait anxiety in adolescence | | 通过脑电图超扫描技术揭示互动大脑间的信息对齐 | Moerel, D. | PDF | N/A | Unlocking information alignment between interacting brains with EEG hyperscanning | | 时间重复性作为解释听觉系统中神经反应的一般机制 | Rancon, U. | PDF | N/A | Temporal recurrence as a general mechanism toexplain neural responses in the auditory system | | 一种植物有益细菌的细胞外囊泡在植物中触发独特的系统反应 | Zannis-Peyrot, T. | PDF | N/A | Extracellular vesicles of a phytobeneficial bacterium trigger distinct systemic response in plant | | 2.3 A A21的结构，一种保守的痘病毒进入融合复合体的蛋白质成分 | Diesterbeck, U. S. | PDF | N/A | The 2.3 A Structure of A21, a Protein Component of the Conserved Poxvirus Entry-Fusion Complex | | 以下是这段英文的中文翻译：
老年参与者肌肉、活动能力和衰老研究中VO2峰值（最大摄氧量）的MicroRNA特征
翻译说明： - MicroRNA signatures：MicroRNA特征，指与特定生理状态或疾病相关的MicroRNA表达模式。 - VO2peak：最大摄氧量，是衡量心肺功能和有氧运动能力的重要指标。 - Study of Muscle, Mobility and Aging：肌肉、活动能力和衰老研究，是一项针对老年人的研究项目。
希望这个翻译对你有帮助！ | Karere, G. | PDF | N/A | MicroRNA signatures of VO2peak in older adult participants of the Study of Muscle, Mobility and Aging | | 进化稀疏学习与配对物种对比揭示了趋同性状的共享遗传基础 | Kumar, S. | PDF | N/A | Evolutionary sparse learning with paired species contrast reveals the shared genetic basis of convergent traits | | 人类蛋白质编码体细胞突变在不同组织和个体中的分布情况 | Xu, H. | PDF | N/A | Landscape of human protein-coding somatic mutations across tissues and individuals | | 分枝杆菌NDH-2与2-巯基喹唑啉酮抑制剂结合的结构 | Liang, Y. | PDF | N/A | Structure of mycobacterial NDH-2 bound to a 2-mercapto-quinazolinone inhibitor | | 多组学和生化重建揭示了CDK7依赖的机制，这些机制控制着RNA聚合酶II在基因5'端和3'端的功能。 | Luyties, O. | PDF | N/A | Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3'-ends | | 以下是这段英文的中文翻译：
战略性地调节基于双分子转子荧光团的极性和粘度敏感性以用于α-突触核蛋白成像
翻译说明： - "Strategic Modulation" 译为“战略性地调节”，强调有目的性的调整。 - "Polarity and Viscosity Sensitivity" 译为“极性和粘度敏感性”，指荧光团对极性和粘度的响应特性。 - "Bimane Molecular Rotor-Based Fluorophores" 译为“基于双分子转子的荧光团”，指以双分子转子为基础的荧光分子。 - "for Imaging α-Synuclein" 译为“用于α-突触核蛋白成像”，说明其应用方向是α-突触核蛋白的成像研究。 | Yarra, V. | PDF | N/A | Strategic Modulation of Polarity and Viscosity Sensitivity of Bimane Molecular Rotor-Based Fluorophores for Imaging α-Synuclein | | 分子动力学指导下的维多利亚水母绿色荧光蛋白（Aequorea victoria Green Fluorescent Protein）发色团相互作用工程，成功生成了一种更亮且具有改进抗光漂白性能的变体。 | Ahmed, R. | PDF | N/A | Molecular dynamics guided engineering of Aequorea victoria Green Fluorescent Protein chromophore interactions generates a brighter variant with improved photobleaching resistance | | 两种独立的易位模式驱动神经干细胞向人类胎儿大脑皮层的扩散 | Wimmer, R. | PDF | N/A | Two independent translocation modes drive neural stem cell dissemination into the human fetal cortex | | 人类REXO4是细胞周期进程所必需的 | Clutario, K. M. | PDF | N/A | Human REXO4 is Required for Cell Cycle Progression | | 肌球蛋白II活性对限制的快速适应维持了中性粒细胞在毛细血管中的迁移 | Deygas, M. | PDF | N/A | Fast adaptation of Myosin II activity to confinement sustains neutrophil migration in capillaries | | 伯格-霍尔姆氧钼酶模型氧原子转移反应的新解释：高活性氧原子转移受体的证据 | Berg, J. M. | PDF | N/A | A New Interpretation for Oxygen Atom-Transfer Reactions for the Berg-Holm Oxo-Molybdenum Enzyme Model: Evidence for a Highly Active Oxygen Atom Transfer Acceptor | | 设计和表征HIV-1疫苗候选物以引发针对多个表位的抗体 | Gristick, H. B. | PDF | N/A | Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes | | 19S蛋白酶体缺失通过不依赖泛素的KIF11降解导致单极纺锤体的形成。 | Marescal, O. | PDF | N/A | 19S proteasome loss causes monopolar spindles through ubiquitin-independent KIF11 degradation | | 人类海马体中的涟漪预示着经验与网格状图式的对齐。 | Xiao, Z. | PDF | N/A | Human hippocampal ripples predict the alignment of experience to a grid-like schema | | 自闭症小鼠模型中PV环路稳态的生理和分子损伤 | Monday, H. R. | PDF | N/A | Physiological and molecular impairment of PV circuit homeostasis in mouse models of autism | | 海马体-皮层连接与个体差异及在区分相似记忆方面的训练收益有关。 | Iliopoulos, P. | PDF | N/A | Hippocampal-cortical connectivity relates to inter-individual differences and training gains in distinguishing similar memories | | 视网膜方向选择性的球形编码使得在集成和视网膜定位操作中能够进行解码。 | Laniado, D. D. | PDF | N/A | Spherical code of retinal orientation-selectivity enables decoding in ensembled and retinotopic operation | | 评估Garmin压力水平评分与心率变异性测量的对比 | Rosenbach, H. | PDF | N/A | Assessing Garmin Stress Level Score Against Heart Rate Variability Measurements | | 大浮萍（Spirodela polyrhiza）中的多倍体-二倍体共存现象 | Mortier, F. | PDF | N/A | Polyploid - diploid coexistence in the greater duckweed Spirodela polyrhiza | | 在巴西钩虫（Nippostrongylus brasiliensis）感染期间，迁移性皮肤γδ T细胞决定了肺部免疫与组织损伤之间的平衡。 | Papotto, P. H. | PDF | N/A | Migratory dermal gamma delta T cells determine the balance between lung immunity and tissue damage during Nippostrongylus brasiliensis infection | | 以下是这段英文的中文翻译：
脆性X综合征大鼠模型中头部方向信号的年龄依赖性变化
翻译解释： - Age-dependent：年龄依赖性的，表示与年龄相关的。 - alterations：变化，指在某个方面的改变。 - head-direction signal：头部方向信号，通常指动物在空间导航中头部朝向的信号。 - rat model：大鼠模型，指用大鼠作为研究对象建立的实验模型。 - Fragile X Syndrome：脆性X综合征，一种遗传性智力障碍疾病。
整句话的意思是：在脆性X综合征的大鼠模型中，头部方向信号会随着年龄的增长而发生改变。 | Moore, N. | PDF | N/A | Age-dependent alterations in the head-direction signal in a rat model of Fragile X Syndrome | | 揭示失忆小鼠中的隐藏知识 | Santi, A. | PDF | N/A | Revealing hidden knowledge in amnestic mice | | 调节细胞衰老可调控整合应激反应信号以控制血细胞稳态 | Ghosh, K. | PDF | N/A | Modulation of cellular ageing regulates Integrated Stress Response signalling to control blood cell homeostasis | | 在早期蛹发育过程中，组织生长模式的转换延长了果蝇翅原基的生长阶段。 | El Marzkioui, K. | PDF | N/A | A switch in the mode of tissue growth extends the growth phase of Drosophila wing primordia during early pupal development | | microRNA-210通过靶向线粒体自噬增强细胞存活和旁分泌潜能，用于心脏细胞治疗。 | Alonaizan, R. | PDF | N/A | microRNA-210 enhances cell survival and paracrine potential for cardiac cell therapy while targeting mitophagy. | | 胎儿的造血祖细胞具有独特的起源和命运 | Soares-da-Silva, F. | PDF | N/A | Distinct origin and fate for fetal hematopoietic progenitors | | 保守的核形态识别功能性放射状胶质神经祖细胞 | Soriano, J. P. | PDF | N/A | CONSERVED NUCLEAR MORPHOLOGY IDENTIFIES FUNCTIONAL RADIAL GLIA NEURAL PROGENITORS | | 在发育中的果蝇眼睛和翅膀中敲除PR-DUB亚单位calypso会导致组织模式异常，大小和形状发生改变。 | Luf, M. | PDF | N/A | Knockdown of PR-DUB subunit calypso in the developing Drosophila eye and wing results in mis-patterned tissues with altered size and shape | | 肠道RICT-1通过卵黄蛋白VIT-3调控秀丽隐杆线虫幼虫生殖细胞前体库 | Kloock, A. | PDF | N/A | Intestinal RICT-1 regulates the larval germline progenitor pool via the vitellogenin VIT-3 in C. elegans | | Foxi2和Sox3是控制外胚层胚层分化的主要调控因子。 | Hendrickson, C. | PDF | N/A | Foxi2 and Sox3 are master regulators controlling ectoderm germ layer specification | | 利用谱系追踪和单细胞转录组学解析斑马鱼肝胆管的异质性和细胞可塑性 | Mi, J. | PDF | N/A | Deciphering the zebrafish hepatic duct heterogeneity and cell plasticity using lineage tracing and single-cell transcriptomics | | 在斑马鱼生长突增期间，胆管细胞在部分肝脏损伤后对肝细胞的再生起到了贡献作用。 | Eski, S. E. | PDF | N/A | Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish | | 血清素抑制雌性慈鲷鱼的性接受能力 | Lee, P. | PDF | N/A | Serotonin inhibits sexual receptivity in female cichlid fish | | 金丝雀在繁殖季节过渡期间对独唱和重叠歌唱的调节方式有所不同 | Totiger, S. | PDF | N/A | Canaries differentially modulate solo and overlapping singing during the transition to the breeding season | | 婴儿习惯化的理性信息收集解释 | Karni, G. | PDF | N/A | A Rational Information Gathering Account of Infant Habituation | | JNK通路抑制导致ER+乳腺癌对联合内分泌治疗和CDK4/6抑制的耐药性 | Alexandrou, S. | PDF | N/A | JNK pathway suppression drives resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer | | 上下文依赖性翻译抑制作为一种新型肿瘤治疗模式 | Diamond, P. D. | PDF | N/A | Context-dependent translation inhibition as a novel oncology therapeutic modality | | 一项整合了单细胞和空间转录组学的甲状腺癌进展图谱研究，识别出了具有预后意义的成纤维细胞亚群。 | Loberg, M. A. | PDF | N/A | An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations | | 氧化磷酸化受损驱动原发性肿瘤逃逸和转移 | Arner, E. N. | PDF | N/A | Impaired oxidative phosphorylation drives primary tumor escape and metastasis | | 上游开放阅读框翻译增强了有丝分裂停滞癌细胞中免疫原性肽的呈递 | Kowar, A. | PDF | N/A | Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells | | APMAT分析揭示了CD8 T细胞受体、同源抗原以及T细胞表型和持久性之间的关联。 | Xie, J. | PDF | N/A | APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence | | 与COVID-19严重程度相关的DPP9基因调控变异的鉴定与功能表征 | Farah, G. | PDF | N/A | Identification and Functional Characterization of Regulatory Variants in DPP9 Associated with COVID-19 Severity | | 设计新型合成启动子以调节T细胞中的基因表达 | Bonfa, G. | PDF | N/A | Design of novel synthetic promoters to tune gene expression in T cells | | 在二十面体病毒解组装过程中基因组RNA的有序释放 | Zhou, Y. | PDF | N/A | Ordered release of genomic RNA during icosahedral virus disassembly | | 重新审视多西环素暴露后预防（doxy-PEP）对奈瑟菌共生菌中多西环素耐药性选择的潜在影响 | Robinson, L. R. | PDF | N/A | Re-visiting the potential impact of doxycycline post-exposure prophylaxis (doxy-PEP) on the selection of doxycycline resistance in Neisseria commensals | | 宏转录组学揭示了珊瑚Porites lutea中“谁在做什么”的情况。 | Tandon, K. | PDF | N/A | Metatranscriptomics sheds light on 'who is doing what' in the coral Porites lutea | | 膳食蛋白质来源通过直接影响以及与肠道微生物群的相互作用，改变了蛋白酶、肠上皮和免疫蛋白的丰度。 | Awan, A. | PDF | N/A | Source of dietary protein alters the abundance of proteases, intestinal epithelial and immune proteins both directly and via interactions with the gut microbiota | | UFMylation促进正黄病毒属感染性颗粒的产生 | Schmidt, H. M. | PDF | N/A | UFMylation promotes orthoflavivirus infectious particle production | | 环指E3连接酶RNF25独立于其在泛素信号传导中的典型作用保护DNA复制叉 | Chiou, L. F. | PDF | N/A | The RING Finger E3 Ligase RNF25 Protects DNA Replication Forks Independently of its Canonical Roles in Ubiquitin Signaling | | METTL3通过促进m6A-YTHDC1依赖的SGK1基因转录加剧内膜增生 | huang, J. | PDF | N/A | METTL3 Aggravates Intimal Hyperplasia by Facilitating the m6A-YTHDC1-dependent SGK1 Gene Transcription | | 核仁应激诱导化合物影响RNA聚合酶I转录机制对rDNA的占据 | Yglesias, M. V. | PDF | N/A | Nucleolar Stress-inducing Compounds Influence rDNA occupancy of RNA Polymerase I Transcription Machinery | | SLFN11介导的tRNA调控通过破坏蛋白质稳态来诱导细胞死亡，以响应DNA损伤剂。 | Iimori, Y. | PDF | N/A | SLFN11-mediated tRNA regulation induces cell death by disrupting proteostasis in response to DNA-damaging agents | | 严格的肠道来源细胞外囊泡分离流程及其对潜伏HIV的影响 | Anyanwu, N. C. J. | PDF | N/A | Rigorous process for isolation of gut-derived extracellular vesicles and the effect on latent HIV | | 通过结构分析揭示了海洋假交替单胞菌中完整的{λ}-卡拉胶降解级联反应。 | Vickers, C. J. | PDF | N/A | The complete {lambda}-carrageenan depolymerization cascade from a marine Pseudoalteromonad revealed by structural analysis of the enzymes. | | AMPylation调节PLD3的加工过程。 | Hoffmann, L. | PDF | N/A | AMPylation regulates PLD3 processing. | | 整合素α5靶向抗体的结构和功能表征用于抗血管生成治疗 | Nguyen, A. | PDF | N/A | Structural and functional characterization of integrin a5-targeting antibodies for anti-angiogenic therapy | | Ag+调控的凝血酶适配体 | Alieva, R. | PDF | N/A | Ag+-regulated aptamers to thrombin | | 前导链和滞后链上的脱碱基位点对脊椎动物复制体的进程有不同的影响，但涉及类似的旁路机制。 | Cranford, M. T. | PDF | N/A | Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms | | 以下是这段文字的中文翻译：
结构洞察白色念珠菌锌载体Pra1的锌清除机制
这段文字主要介绍了通过结构研究来理解白色念珠菌（Candida albicans）中的锌载体蛋白Pra1如何清除锌的机制。 | Syrjanen, J. L. | PDF | N/A | Structural insights into mechanisms of zinc scavenging by the Candida albicans zincophore Pra1 |