BioRxiv 2025-01-10 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 过表达受体样激酶BIR1基因会导致拟南芥中依赖SOBIR1和EDS1的细胞死亡表型。 | Guzman-Benito, I. | N/A | Overexpression of the receptor-like kinase BIR1 gene causes SOBIR1- and EDS1-dependent cell death phenotypes in Arabidopsis | |
| 猴痘病毒在细胞间传播,并在人类神经类器官中导致神经元死亡。 | Schultz-Pernice, I. | N/A | Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids | |
| 解码人类大脑中观察到的动作的物理原理 | Wurm, M. F. | N/A | Decoding the physics of observed actions in the human brain | |
| 撤回:伽马疱疹病毒感染改变了转移RNA的剪接并引发tRNA的切割 | Manning, A. C. | N/A | WITHDRAWN: Gammaherpesvirus infection alters transfer RNA splicing and triggers tRNA cleavage | |
| 超灵敏元蛋白质组学重新定义了肠道暗元蛋白质组,揭示了肠道炎症性疾病中的宿主-微生物组相互作用及药物靶点。 | Xian, F. | N/A | Ultra-sensitivity metaproteomics redefines the gut dark metaproteome, uncovering host-microbiome interactions and drug targets in intestinal inflammatory diseases. | |
| 撤回:人为电磁场对地磁位移鳐鱼行为的影响 | NEWTON, K. | N/A | WITHDRAWN: The Effects of Anthropogenic Electromagnetic Fields on the Behavior of Geomagnetically Displaced Skates | |
| 通过使用自发的视网膜活动对人工神经网络进行预训练,可以提高其在自然场景中的运动预测能力。 | May, L. | N/A | Pre-training artificial neural networks with spontaneous retinal activity improves motion prediction in natural scenes | |
| 通过研究柳枝稷中多个因素来优化复杂性状的基因组预测 | Wang, P. | N/A | Optimizing genomic prediction for complex traits via investigating multiple factors in switchgrass | |
| 以下是这段文字的中文翻译: |
受驱动蛋白和原肌球蛋白马达失调影响的收缩性细胞骨架结构的瞬时流动分析
这个标题涉及对细胞骨架结构在驱动蛋白(kinesin)和原肌球蛋白(tropomyosin)马达失调情况下的瞬时流动行为的研究。细胞骨架是细胞内维持形状和运动的关键结构,而驱动蛋白和原肌球蛋白是调控其动态行为的重要分子马达。研究这些马达的失调如何影响细胞骨架的收缩性和流动特性,有助于理解细胞力学和疾病机制。 | Matov, A. | PDF | N/A | Instantaneous Flow Analysis of Contractile Cytoskeletal Structures Affected by the Dysregulation of Kinesin and Tropomyosin Motors | | 证明你的残疾!模拟医学评估作为慢性疼痛患者的一种强有力的新型压力诱导范式。 | Chiron, A. | PDF | N/A | Justify your disability! A simulated medical evaluation as a robust novel stress induction paradigm in chronic pain patients. | | 撤回:神经效率评分的验证与应用 | Wenger, M. J. | PDF | N/A | WITHDRAWN: The Neural efficiency score: Validation and application | | 撤回:卤虫(Artemia leach, 1819,鳃足纲:无甲目)的线粒体基因组系统发育及分化时间估计,重点关注孤雌生殖谱系 | Asem, A. | PDF | N/A | WITHDRAWN: Mitogenomic phylogeny and divergence time estimation of Artemia leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages | | 大鼠内侧颞叶中感觉与恐惧记忆的整合 | Wong, F. S. | PDF | N/A | Integration of sensory and fear memories in the rat medial temporal lobe | | 对意大利南部浮萍物种的一项调查首次记录了杂交种地中海浮萍(Lemna x mediterranea)在自然环境中的分布情况。 | Romano, L. E. | PDF | N/A | A survey of duckweed species in Southern Italy provided first distribution records of the hybrid Lemna x mediterranea in nature | | 心磷脂缺乏在脂肪性肝炎中破坏了CoQ-复合物III的界面 | Brothwell, M. J. | PDF | N/A | Cardiolipin deficiency disrupts CoQ-complex III interface in steatohepatitis | | 斑马鱼中rbfox1功能缺失导致bdnf/trkb2和pac1a表达失调,进而引发HPI轴过度激活、应激反应改变以及稳态过载。 | Leggieri, A. | PDF | N/A | rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload | | 由植物乳杆菌SJ33产生的新型低分子量化合物对肺炎克雷伯菌的抗生物膜活性 | Ray Mohapatra, A. | PDF | N/A | Anti-biofilm activity of new low molecular weight compounds produced by Lactiplantibacillus plantarum SJ33 against Klebsiella pneumoniae | | 团结一致:从退化的永久冻土土壤中分离和表征产生胞外多糖的细菌 | Waqas, M. | PDF | N/A | Stick together: Isolation and characterization of exopolysaccharide producing bacteria from degraded permafrost soils | | TOGGLE通过单细胞转录组学在单一类型的成熟细胞中识别命运和功能过程。 | Chen, J. | PDF | N/A | TOGGLE identifies fate and function process within a single type of mature cell through single-cell transcriptomics | | 以下是这段英文的中文翻译:
短柄草根系结构和解剖对硝酸盐和铵盐适应性的调控分析
翻译说明: - "Regulatory Analysis" 翻译为 "调控分析",表示对某种调控机制的研究。 - "Root Architectural and Anatomical Adaptation" 翻译为 "根系结构和解剖适应性",指植物根系在形态和解剖上的适应性变化。 - "Nitrate and Ammonium" 翻译为 "硝酸盐和铵盐",是两种常见的氮源形式。 - "Brachypodium distachyon" 是植物学名,通常直接保留原文,或翻译为 "短柄草"。
希望这段翻译对你有帮助! | Rouina, H. | PDF | N/A | Regulatory Analysis of Root Architectural and Anatomical Adaptation to Nitrate and Ammonium in Brachypodium distachyon | | 多发性硬化症类器官中的髓鞘形成受损:p21将少突胶质细胞功能障碍与疾病亚型联系起来 | Daviaud, N. | PDF | N/A | Impaired Myelination in Multiple Sclerosis Organoids: p21 Links Oligodendrocyte Dysfunction to Disease Subtype | | 成年人类未成熟神经元在健康衰老、阿尔茨海默病和认知韧性中的独特转录特征 | Tosoni, G. | PDF | N/A | Unique transcriptional profiles of adult human immature neurons in healthy aging, Alzheimer's disease, and cognitive resilience | | SARS-CoV-2 T细胞反应随多次COVID-19加强针接种的演变 | da Silva Antunes, R. | PDF | N/A | Evolution of SARS-CoV-2 T cell responses as a function of multiple COVID-19 boosters | | 牛呼吸道和乳腺上皮细胞对禽源和哺乳动物来源的2.3.4.4b分支H5N1高致病性禽流感病毒的易感性 | Meliopoulos, V. A. | PDF | N/A | Susceptibility of bovine respiratory and mammary epithelial cells to avian and mammalian derived clade 2.3.4.4b H5N1 highly pathogenic avian influenza viruses | | SAMHD1通过线粒体途径增强HIV-1诱导的单核细胞凋亡 | Yang, H. | PDF | N/A | SAMHD1 enhances HIV-1-induced apoptosis in monocytic cells via the mitochondrial pathway | | TERRA R环触发端粒维护机制向断裂诱导复制和依赖PrimPol的修复方向转变。 | Lingner, J. | PDF | N/A | TERRA R-loops trigger a switch in telomere maintenance towards break-induced replication and PrimPol-dependent repair | | 通过多反应监测质谱法和QconCAT蛋白标准对溶酶体蛋白进行绝对定量 | Mosen, P. R. | PDF | N/A | Absolute Quantification of Lysosomal Proteins by Multiple Reaction Monitoring Mass Spectrometry and QconCAT Protein Standards | | 群体遗传学中模型变异下的选择和时序推断的稳健性 | Escabi, J. | PDF | N/A | Robustness of Selection and Timing Inference under Model Variation in Population Genetics | | 基因组和宏基因组对微生物碳酸酐酶基因的调查揭示了新的进化分支、高度多样性以及生物群落特异性 | Franco, M. E. E. | PDF | N/A | Genomic and metagenomic survey of microbial carbonic anhydrase genes reveals novel clades, high diversity, and biome-specificity | | N6-甲基腺苷和NEXT复合物调控Xist RNA的降解与X染色体失活动力学 | Wei, G. | PDF | N/A | N6-methyladenosine and the NEXT complex direct Xist RNA turnover and X inactivation dynamics | | HAPLN2的聚集是小鼠大脑生理老化的一个标志,HAPLN2是周围结细胞外基质的一个组成部分。 | Watanabe, A. | PDF | N/A | Aggregation of HAPLN2, a component of the perinodal extracellular matrix, is a hallmark of physiological brain aging in mice | | Cas12a蛋白的桥螺旋的螺旋转变是R-loop形成和RuvC激活的变构调节因子。 | Ganguly, C. | PDF | N/A | Helical transition of the bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation | | CpgD是一种磷酸甘油酸胞苷酰转移酶,是合成神经酰胺二磷酸甘油酯所必需的。 | Dhakephalkar, T. | PDF | N/A | CpgD is a phosphoglycerate cytidylyltransferase required for ceramide diphosphoglycerate synthesis | | PrfH亚家族在拯救翻译过程中停滞的受损和完整核糖体的分子和结构基础 | Tian, Y. | PDF | N/A | Molecular and structural basis of a subfamily of PrfH rescuing both the damaged and intact ribosomes stalled in translation | | N端的无序-有序转变是IscU变构的关键决定因素。 | Na, J. | PDF | N/A | The N-terminal order-disorder transition is a critical determinant for a metamorphosis of IscU | | 拟杆菌目T6SS小亚基Hcp形成识别效应蛋白的异聚体。 | San-Miguel, S. G. | PDF | N/A | Bacteroidales T6SS minor Hcp subunits form heteromers recognising effectors | | 利用人类多能干细胞衍生的骨骼组装体模拟人类肢体骨骼发育 | Takao, T. | PDF | N/A | Modeling the human limb skeletal development using human pluripotent stem cell-derived skeletal assembloid | | 阿尔茨海默病对大脑结构和行为影响的全球性剖析:高分辨率磁共振成像揭示显著的区域效应
在这项研究中,我们通过高分辨率磁共振成像(MRH)技术,对阿尔茨海默病(Alzheimer's disease, AD)对大脑结构和行为的影响进行了全面的全球性剖析。研究结果表明,AD在大脑的不同区域产生了显著的影响,这些影响不仅体现在大脑结构的改变上,也反映在患者的行为和认知功能上。高分辨率MRH技术为我们提供了详细的大脑图像,使我们能够精确地识别和量化这些区域性的变化,从而更深入地理解AD的病理机制及其对患者生活质量的影响。 | Johnson, G. A. | PDF | N/A | Global dissection of the impact of Alzheimer's disease on brain architecture and behavior: High resolution MRH resolves robust regional effects | | 伏隔核中Shank3的缺乏揭示了社交特异性动机的丧失 | Folkes, O. M. | PDF | N/A | Deficiency of Shank3 in the Nucleus Accumbens Reveals a Loss of Social-Specific Motivation | | 中脑扩展杏仁核及其他社交行为网络中心的Otp谱系儿茶酚胺能神经元的发育 | Morales, L. | PDF | N/A | Development of catecholaminergic neurons of Otp-lineage in the medial extended amygdala and other centers of the social behavior network | | 在计算机编程指令后,前顶叶推理系统中逻辑算法表示的快速“循环利用” | Liu, Y.-F. | PDF | N/A | Rapid "recycling" of logical algorithm representations in fronto-parietal reasoning systems following computer programming instructions | | Replay在离线状态下构建了一个高效的认知地图,以避免在线计算。 | Ou, J. | PDF | N/A | Replay builds an efficient cognitive map offline to avoid computation online | | 人类皮质层中的预测性声学处理 | Faes, L. K. | PDF | N/A | Predictive acoustical processing in human cortical layers | | C12ORF57:突触AMPA电流和兴奋性神经元稳态的新型主要调节因子 | Jiang, R. | PDF | N/A | C12ORF57: a novel principal regulator of synaptic AMPA currents and excitatory neuronal homeostasis | | 神经板预模式化使得脊髓中中间神经前体细胞的特定化成为可能。 | Nandagopal, S. | PDF | N/A | Neural plate pre-patterning enables specification of intermediate neural progenitors in the spinal cord | | 以下是将“Generation and Characterization of a Knockout Mouse of an Enhancer of EBF3”翻译成中文的结果:
EBF3增强子的基因敲除小鼠的构建与表征
这个标题描述了一项研究,旨在通过基因编辑技术构建EBF3基因增强子的敲除小鼠模型,并对其表型和功能进行详细分析。 | Hurtado, E. C. | PDF | N/A | Generation and Characterization of a Knockout Mouse of an Enhancer of EBF3 | | 响应面法优化大枣果肉总黄酮提取工艺及其镇静催眠作用研究
翻译说明: 1. "Optimization of Extraction Process by Response Surface Methodology" 翻译为 "响应面法优化提取工艺",其中 "响应面法" 是常用的统计优化方法,"提取工艺" 指的是从原料中提取目标成分的过程。 2. "Total Flavonoids from Ziziphus Jujube Flesh" 翻译为 "大枣果肉总黄酮",其中 "Ziziphus Jujube" 是 "大枣" 的学名,"Flesh" 指的是果肉部分,"总黄酮" 是指一类具有生物活性的化合物。 3. "Sedative-Hypnotic Effects" 翻译为 "镇静催眠作用",指的是药物或化合物对中枢神经系统的抑制作用,能够帮助缓解焦虑和促进睡眠。
整体翻译保持了原文的专业性和准确性,同时符合中文的表达习惯。 | Yang, Y. | PDF | N/A | Optimization of Extraction Process by Response Surface Methodology of Total Flavonoids from Ziziphus Jujube Flesh and its Sedative-Hypnotic Effects | | 水稻幼苗根部的微观形态及铵离子跨膜运输特性 | Zhang, X. | PDF | N/A | Micromorphology and ammonium transmembrane transport characteristics in roots of rice seedlings | | PSI Atlas:一个全面的植物自交不亲和性知识库 | Wang, C. | PDF | N/A | PSI Atlas: a comprehensive knowledgebase of plant self-incompatibility | | Anillin 直接将微管与纤维状肌动蛋白交联在一起。 | Bareja, I. | PDF | N/A | Anillin directly cross-links microtubules with filamentous actin | | ATR和PKMYT1抑制使一部分三阴性乳腺癌(TNBC)患者来源的模型重新对卡铂敏感,导致有丝分裂灾难。 | Guay, J. | PDF | N/A | ATR and PKMYT1 inhibition re-sensitize a subset of TNBC patient-derived models to carboplatin inducing mitotic catastrophe | | SUPERKILLER (SKI)复合体的亚基3介导了miR172引导的结节数控制1 (NNC1)的切割,以调节蒺藜苜蓿(Medicago truncatula)中的结瘤过程。 | Traubenik, S. | PDF | N/A | The subunit 3 of the SUPERKILLER (SKI) complex mediates miR172-directed cleavage of Nodule Number Control 1 (NNC1) to modulate nodulation in Medicago truncatula | | 机械力对人脑类器官中神经干细胞命运决定的影响 | Falk, S. | PDF | N/A | Mechanical impact on neural stem cell lineage decisions in human brain organoids | | 对白色念珠菌中CRISPR-Cas9等位基因编辑系统的比较评估:在一种具有挑战性的病原体中进行的研究 | Carolus, H. | PDF | N/A | A comparative evaluation of CRISPR-Cas9 allele editing systems in Candida auris: challenging research in a challenging bug | | 蓝藻素B(Cyanochelin B):这是一种由蓝藻Leptolyngbya sp. NIES-3755产生的铁载体(siderophore),具有光解特性,能够在紫外线照射下阻止铁的独占。 | Falcao, B. P. | PDF | N/A | Cyanochelin B: A siderophore produced by cyanobacterium Leptolyngbya sp. NIES-3755 with photolytic properties that negate iron monopolization in the UV-light | | 大规模基于培养的方法用于从复杂样本中筛选产AmpC、ESBL和碳青霉烯酶的菌株 | Taddeucci-Rocha, G. | PDF | N/A | Massive culture-based approach for the screening of AmpC-, ESBL- and carbapenemase producers from complex samples | | 烟酸通过增强SIRT1和SIRT6信号通路以及促进血管平滑肌细胞(VSMC)自噬来防止血管钙化。 | Chen, S.-l. | PDF | N/A | Niacin protects against vascular calcification via enhanced SIRT1 and SIRT6 signaling and promoted VSMC autophagy | | ERGA-BGE 基因组:Erebia palarica Chapman, 1905,一种仅分布于伊比利亚西北部山区的蝴蝶 | Vila, M. | PDF | N/A | ERGA-BGE genome of Erebia palarica Chapman, 1905: a montane butterfly endemic to North-West Iberia | | 迁移学习应用于预测小分子生物活性 | Tian, L. | PDF | N/A | Transfer learning applied in predicting small molecule bioactivity | | 使用计算机模型预测非小细胞肺癌的个性化治疗组合 | Clarke, M. A. | PDF | N/A | Predicting Personalised Therapeutic Combinations in Non-Small Cell Lung Cancer Using In Silico Modelling | | PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1通过与SAR1 GTPase相互作用参与COPII组装。 | Lung, H.-F. | PDF | N/A | Involvement of PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 in COPII assembly by interacting with SAR1 GTPase | | 人体运动中高维协调性的方差谱缩放分析 | Dotov, D. | PDF | N/A | Variance spectrum scaling analysis for high-dimensional coordination in human movement | | 多巴胺和血清素对人类奖励与惩罚过程的不同影响:一项系统综述与荟萃分析 | Mkrtchian, A. | PDF | N/A | Differential effects of dopamine and serotonin on reward and punishment processes in humans: A systematic review and meta-analysis | | 新学习单词巩固期间的α和β去同步化 | Zappa, A. | PDF | N/A | Alpha and beta desynchronization during consolidation of newly learned words | | 综合感染组分析揭示野生动物中具有人畜共患潜力的多种传染性病原体 | Hou, X. | PDF | N/A | Comprehensive Infectome Analysis Reveals Diverse Infectious Agents with Zoonotic Potential in Wildlife | | 二肽酶1是冠状病毒PHEV的功能性受体。 | Dufloo, J. | PDF | N/A | Dipeptidase 1 is a functional receptor for coronavirus PHEV | | 西班牙月蛾(Graellsia isabellae Graells, 1849)的ERGA-BGE基因组:一种受《栖息地指令》保护的夜行性鳞翅目昆虫 | Vila, M. | PDF | N/A | ERGA-BGE genome of the Spanish Moon Moth Graellsia isabellae Graells, 1849: a nocturnal lepidopteran protected by the Habitats Directive | | 酵母热休克反应期间的动态全局乙酰化重塑 | Hardman-Kavanaugh, R. E. | PDF | N/A | Dynamic global acetylation remodeling during the yeast heat shock response | | 限制器减缓早期转录延伸,使RNA聚合酶II在非编码RNA位点上易于终止。 | Mimoso, C. A. | PDF | N/A | Restrictor slows early transcription elongation to render RNA polymerase II susceptible to termination at non-coding RNA loci | | ISFP10的临床前和毒理学评估,一种真菌磷酸葡萄糖变位酶(PGM)抑制剂 | Pellegrino, M. | PDF | N/A | Preclinical and Toxicology Assessment of ISFP10, an Inhibitor of Fungal Phosphoglucomutase (PGM) | | 严重缺铁会促进拟南芥中低氧诱导反应的发生。 | Telara, Y. | PDF | N/A | Severe Fe deficiency promotes hypoxia inducible responses in Arabidopsis thaliana | | 为了在拟南芥中实现侧根的空间适应,需要一个严格调控的生长素信号景观。 | Bui, T. X. | PDF | N/A | A tightly regulated auxin signaling landscape is required for spatial accommodation of lateral roots in Arabidopsis | | 星形醋酸格拉替雷缓解隐球菌相关IRIS小鼠模型中的肺功能障碍和脑神经退行性变 | Anwar, S. | PDF | N/A | Star-Shaped Glatiramer Acetate Mitigates Pulmonary Dysfunction and Brain Neurodegeneration in a Murine Model of Cryptococcus-Associated IRIS | | 二氧化硅介导的炎症性关节炎恶化:一种新型小鼠模型 | Janssen, L. M. F. M. F. | PDF | N/A | Silica-mediated exacerbation of inflammatory arthritis: A novel murine model | | 分泌型Nimrod蛋白NimB1在果蝇中负调控凋亡细胞吞噬的早期步骤。 | Dolgikh, A. | PDF | N/A | The secreted Nimrod NimB1 negatively regulates early steps of apoptotic cell phagocytosis in Drosophila | | 从幼虫阶段到成年期?火蜥蜴幼虫的栖息地类型特异性化学指纹可能为成年后的配偶选择提供初步线索。 | Schulte, L. | PDF | N/A | From larval stage to adulthood? Habitat type-specific chemical fingerprints of fire salamander larvae might give first indication for adult mate preference | | 沿着环境干扰梯度的河口微型底栖生物群落中的动态和生物关联网络对比 | Garate, L. | PDF | N/A | Contrasting dynamics and biotic association networks in estuarine microbenthic communities along an environmental disturbance gradient | | NERINE揭示了跨多种表型的基因网络中罕见的变异关联,并暗示了SNCA-PRL-LRRK2子网络在帕金森病中的作用。 | Nazeen, S. | PDF | N/A | NERINE reveals rare variant associations in gene networks across multiple phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in Parkinson's disease | | 古代基因簇启动单萜吲哚生物碱的生物合成和C-3立体化学反转 | Hwang, J. | PDF | N/A | Ancient gene clusters initiate monoterpene indole alkaloid biosynthesis and C-3 stereochemistry inversion | | 多孔支架的Vat光聚合:微米级精度的稳定化与层厚控制 | Chen, G. | PDF | N/A | Vat Photopolymerization of Porous Scaffolds: Stabilization and Layer Thickness Control for Micron-Scale Accuracy | | 研究合成细菌群落中劳动分工在生产紫色杆菌素中的潜力 | Mehta, H. | PDF | N/A | Investigating The Potential of Division of Labour in Synthetic Bacterial Communities for the Production of Violacein | | 利用计算洞察力识别人类偏肺病毒(HMPV)的有效抑制剂:与天然化合物的协同方法 | Dubey, A. | PDF | N/A | Harnessing Computational Insights to Identify Potent Inhibitors for Human Metapneumovirus (HMPV): A Synergistic Approach with Natural Compounds | | 构象门控结合驱动ATP:钴(I)胺素腺苷转移酶中的负协同效应,以实现优化的钴胺素处理 | Yan, G. | PDF | N/A | Conformation-gated binding drives negative cooperativity in ATP:cob(I)alamin Adenosyltransferase for optimized cobalamin handling | | 胆固醇依赖性EphA2受体的二聚化与构象动力学:基于粗粒化和全原子模拟的见解
在这段翻译中,我尽量保持了原文的专业性和准确性。以下是对翻译的简要解释:
- Cholesterol-Dependent 翻译为“胆固醇依赖性”,指的是与胆固醇相关的特性或过程。
- Dimerization 翻译为“二聚化”,指的是两个分子(如蛋白质)结合形成一个二聚体的过程。
- Conformational Dynamics 翻译为“构象动力学”,指的是分子在空间中的形状和结构随时间的变化。
- EphA2 Receptors 翻译为“EphA2受体”,EphA2是一种特定的受体蛋白。
- Insights from 翻译为“基于……的见解”,表示从某种方法或研究中得出的结论或理解。
- Coarse-Grained and All-Atom Simulations 翻译为“粗粒化和全原子模拟”,这是两种不同的分子模拟方法,分别用于研究分子系统的不同层面。
希望这个翻译对您有帮助!如果有任何进一步的问题或需要更详细的解释,请随时告诉我。 | Sahoo, A. R. | PDF | N/A | Cholesterol-Dependent Dimerization and Conformational Dynamics of EphA2 Receptors: Insights from Coarse-Grained and All-Atom Simulations | | 稻曲病菌通过效应蛋白SCRE9促进赤霉素(GA)的生物合成,从而抑制植物的花部免疫反应。 | Yu, S. | PDF | N/A | Ustilaginoidea virens suppresses floral immunity through promoting GA biosynthesis by the effector SCRE9 | | EPISeg:利用开放获取的多中心数据对回波平面图像上的脊髓进行自动分割 | Banerjee, R. | PDF | N/A | EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data | | 一种通过鼻内递送的纳米脂质载体(NLC)传递的自扩增RNA疫苗,能够建立对预流行H5N1和H7N9流感病毒的保护性免疫。 | Ykema, M. R. | PDF | N/A | An intranasal, NLC-delivered self-amplifying RNA vaccine establishes protective immunity against pre-pandemic H5N1 and H7N9 influenza | | 对恒河猴免疫球蛋白基因座变异的广泛调查与功能分析 | Peres, A. | PDF | N/A | A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques | | 温度对蚊子寄生虫感染的非线性效应在广阔的地理气候梯度上的研究 | Farner, J. E. | PDF | N/A | Nonlinear effects of temperature on mosquito parasite infection across a large geographic climate gradient | | 土壤特性的时空变化预测大陆尺度上的植物健康状况 | Wang, N. | PDF | N/A | Spatiotemporal changes in soil properties predict plant health at continental scale | | 使用直线连分数的生物生长模型 | S, S. I. | PDF | N/A | A Biological Growth Model using Continued Fraction of Straight Lines | | 多样性、连通性和负相互作用定义了跨越陆地、溪流和海洋的强大微生物组网络。 | Kajihara, K. T. | PDF | N/A | Diversity, connectivity and negative interactions define robust microbiome networks across land, stream, and sea | | 丝氨酸蛋白酶抑制剂(serpin)基因的串联重复产生了功能变异和蛇毒抑制剂。 | Ward, M. S. | PDF | N/A | Tandem duplication of serpin genes yields functional variation and snake venom inhibitors. | | 一种风媒传粉的草本植物中雌雄异株现象的解释:基于性别分配上的分裂选择 | Chen, K.-H. | PDF | N/A | Dioecy in a wind-pollinated herb explained by disruptive selection on sex allocation | | PARAS:非核糖体肽合成酶底物特异性的高精度机器学习 | Terlouw, B. R. | PDF | N/A | PARAS: high-accuracy machine-learning of substrate specificities in nonribosomal peptide synthetases | | 使用FlexConsensus算法将构象景观合并到一个单一的共识空间中 | Herreros, D. | PDF | N/A | Merging conformational landscapes in a single consensus space with FlexConsensus algorithm | | BellaVista:基于成像的空间转录组学开源可视化工具 | Coles, A. M. | PDF | N/A | BellaVista: Open-Source Visualization for Imaging-Based Spatial Transcriptomics | | Descriptron:测试人工智能以自动化分类学物种描述,附带用户友好软件包 | Van Dam, A. | PDF | N/A | Descriptron: Testing Artificial Intelligence for Automating Taxonomic Species Descriptions with a User-friendly Software Package | | 开发用于Nextclade的禽流感A(H5)病毒数据集,能够实现快速且准确的病毒分支分类。 | Ort, J. T. | PDF | N/A | Development of avian influenza A(H5) virus datasets for Nextclade enables rapid and accurate clade assignment | | 深度学习生成具有隐秘配体结合位点的apo RNA构象 | Kurisaki, I. | PDF | N/A | Deep learning generates apo RNA conformations with cryptic ligand binding site | | 使用rho、theta和phi描述蛋白质结构:以Caenopore-5为例的研究 | Li, W. | PDF | N/A | Protein Structure Description with rho, theta and phi: A Case Study with Caenopore-5 | | sCCIgen:用于细胞间相互作用研究的高保真空间分辨转录组数据模拟器。 | Song, X. | PDF | N/A | sCCIgen: A high-fidelity spatially resolved transcriptomics data simulator for cell-cell interaction studies. | | 有偏抽样混淆了机器学习对抗菌药物耐药性的预测 | Yu, Y. | PDF | N/A | Biased sampling confounds machine learning prediction of antimicrobial resistance | | 使用溶液和固态核磁共振对多药外排膜蛋白的主链和侧链进行1H、15N和13C共振归属 | Harding, B. D. | PDF | N/A | Backbone and Sidechain 1H, 15N and 13C Resonance Assignments of a Multidrug Efflux Membrane Protein using Solution and Solid-State NMR | | 当停止需要行动时;行动取消与取消行动取消之间的生理相似性 | Weber, S. | PDF | N/A | When Stopping Requires Going; Physiological Similarities Between Action Cancellation and the Cancellation of Action Cancellation | | VineColD:一个用于全球历史追踪和实时监测葡萄藤耐寒性的综合数据库 | Wang, H. | PDF | N/A | VineColD: an integrative database for global historical tracing and real-time monitoring of grapevine cold hardiness | | 基于模拟推理的过度兴奋性补偿 | Mueller-Komorowska, D. | PDF | N/A | Compensation of Hyperexcitability with Simulation-Based Inference | | 源自高度可扩展和再生性人类祖细胞的外泌体在缺血性中风大鼠模型中促进功能改善 | Lee, J. | PDF | N/A | Exosomes derived from highly scalable and regenerative human progenitor cells promote functional improvement in a rat model of ischemic stroke | | 通过在人工基质上局部增加碱度,可以提高早期珊瑚幼体的存活率。 | Ruszczyk, M. | PDF | N/A | Local alkalinity enhancement using artificial substrates increases survivorship of early-stage coral recruits | | 自然秀丽隐杆线虫(Caenorhabditis elegans)种群中的基因组结构变异 | Lesack, K. J. | PDF | N/A | Genome structural variation in natural Caenorhabditis elegans populations | | 以下是将这段英文翻译成中文的结果:
一个用于表征个体人类iPSC衍生伤害感受器轴突电生理学的体外平台
解释: - in vitro platform:体外平台,指的是在实验室环境中进行的实验,而不是在活体生物体内。 - characterizing:表征,指的是对某种特性进行详细描述和分析。 - axonal electrophysiology:轴突电生理学,研究轴突(神经细胞的输出部分)的电活动。 - individual human iPSC-derived nociceptors:个体人类iPSC衍生的伤害感受器,指的是从人类诱导多能干细胞(iPSC)分化而来的单个伤害感受器(负责感知疼痛的神经细胞)。
整体翻译传达了原文的科学含义,描述了一个用于研究人类iPSC衍生伤害感受器轴突电生理特性的实验平台。 | Clement, B. F. | PDF | N/A | An in vitro platform for characterizing axonal electrophysiology of individual human iPSC-derived nociceptors | | 使用STAMapper进行单细胞空间转录组学的高精度细胞类型映射与注释 | Shen, Q. | PDF | N/A | High-precision cell-type mapping and annotation of single-cell spatial transcriptomics with STAMapper | | 中枢神经系统轴突的发育性直径增长并不依赖于少突胶质细胞的包裹或髓鞘形成。 | Bin, J. M. | PDF | N/A | Developmental axon diameter growth of central nervous system axons does not depend on ensheathment or myelination by oligodendrocytes | | 生物神经网络的关键初始化 | Pachitariu, M. | PDF | N/A | A critical initialization for biological neural networks | | 在建筑体验期间的大脑动态:前额叶和海马体区域追踪美学与空间复杂性 | Gregorians, L. | PDF | N/A | Brain dynamics during architectural experience: prefrontal and hippocampal regions track aesthetics and spatial complexity | | 由伤寒沙门氏菌感染引起的缺氧相关免疫亚群将早期细菌肠道侵袭与人类感染结果联系起来 | Bossel Ben-Moshe, N. | PDF | N/A | Hypoxia-related immune subsets induced by Salmonella Typhi infection link early bacterial gut invasion to human infection outcomes | | 对类风湿性关节炎滑膜中的空间转录组学进行深度主题建模,识别出异位淋巴结构的不同类别。 | Periyakoil, P. K. | PDF | N/A | Deep topic modeling of spatial transcriptomics in the rheumatoid arthritis synovium identifies distinct classes of ectopic lymphoid structures | | 细胞骨架支架通过调节过渡区完整性促进运动纤毛的组装 | Park, H. | PDF | N/A | A cytoskeletal scaffold promotes motile cilia assembly by regulating transition-zone integrity | | HOXA10介导的子宫内膜上皮-间质转化促进胚胎着床 | Ashary, N. S. | PDF | N/A | Epithelial to Mesenchymal Transition in the Endometrium Mediated by HOXA10 drives Embryo Implantation | | 以下是将这段英文翻译成中文的结果:
烟酰胺腺嘌呤二核苷酸(NAD+)缺乏引起的先天性疾病的斑马鱼模型
希望这个翻译对你有帮助!如果有其他问题,欢迎继续提问。 | Tsurho, V. | PDF | N/A | A zebrafish model of nicotinamide adenine dinucleotide (NAD+) deficiency-derived congenital disorders | | 在人类多能干细胞衍生的心脏类器官上重建冠状动脉血管化和心肌的交感神经支配 | Branco, M. | PDF | N/A | Recreating coronary vascularization and sympathetic innervation of myocardium on a human pluripotent stem cell-derived heart organoid | | 负责巨型粉虫甲虫(Zophobas atratus)不对称下颌齿形成的基因 | Toga, K. | PDF | N/A | Genes responsible for the formation of asymmetrical mandibular teeth in the giant mealworm beetle, Zophobas atratus | | Chd4通过重塑染色质来控制视网膜细胞类型的特化和谱系终止。 | Shah, S. | PDF | N/A | Chd4 remodels chromatin to control retinal cell type specification and lineage termination | | 使用eDNA宏条形码技术与传统捕获法评估淡水鱼类群落:效率与分辨率的差异及其与栖息地和生态的关联 | Curto, M. | PDF | N/A | Freshwater fish community assessment using eDNA metabarcoding vs. capture-based methods: differences in efficiency and resolution coupled to habitat and ecology | | 美国东北部大陆架大西洋鳕鱼的空间密度与栖息地关联 | Lankowicz, K. | PDF | N/A | Spatial density and habitat associations of Atlantic Cod on the Northeastern US Continental Shelf | | Guidestar:一种基于成像的空间转录组学中提高RNA检测准确性的内标方法 | Tan, J. X. M. | PDF | N/A | Guidestar: a spike-in approach to improve RNA detection accuracy in imaging-based spatial transcriptomics | | 猕猴群体内互动的时空动态 | Kononowicz, T. W. | PDF | N/A | Spatio-temporal dynamics of ingroup interactions in macaques | | 通过改进的基于miRNA调控水平网络的方法揭示癌症中性别二态性的分子机制:MIRROR2 | Alfano, C. | PDF | N/A | Molecular mechanisms of sexual dimorphism in cancer through improved miRNA regulation-level network-based approach: MIRROR2 | | 无光刻水稳定导电聚合物纳米线 | Hughes, D. | PDF | N/A | Lithography-free Water Stable Conductive Polymer Nanowires | | 雄性生殖器和腿部的形态揭示了中生代缺翅目(昆虫纲)的分类 | Kocarek, P. | PDF | N/A | Morphology of male genitalia and legs reveals the classification of Mesozoic Zoraptera (Insecta) | | 在接受肠促胰岛素类似物治疗后,通过饮食干预恢复了饮食诱导肥胖小鼠的脂肪组织功能。 | Seuntjens, J. | PDF | N/A | A dietary intervention following incretin analog treatment restores adipose tissue functions in diet-induced obese mice | | 香蕉(Musa acuminata)WRKY基因家族的密码子使用偏好性分析 | Sun, J. | PDF | N/A | Codon Usage Bias Analysis of the WRKY Gene Family in Musa acuminata | | 重访中心法则:基因组、甲基化、转录和翻译在拟南芥蛋白质表达中的独特作用 | Zhong, Z. | PDF | N/A | Revisiting the Central Dogma: the distinct roles of genome, methylation, transcription, and translation on protein expression in Arabidopsis thaliana | | 磷酸化蛋白质组学揭示了慢性髓性白血病中不依赖BCR::ABL1的新型耐药机制 | Bica, V. | PDF | N/A | Phosphoproteomics reveals novel BCR::ABL1-independent mechanisms of resistance in chronic myeloid leukemia | | 源自阿尔茨海默病细胞的大型细胞外囊泡(EVMs)含有线粒体,这些囊泡携带有病理性的功能和分子特征,并传播线粒体功能障碍。 | Eysert, F. | PDF | N/A | Large extracellular vesicles containing mitochondria (EVMs) derived from Alzheimer disease cells harbor pathologic functional and molecular profiles and spread mitochondrial dysfunctions | | 人类自然身体选择性运动处理的证据:来自事件相关电位的研究 | Chesley, J. | PDF | N/A | Natural body-selective motion processing in humans: Evidence from event-related potentials | | VE-cadherin的RGD基序对于细胞间连接、内皮屏障功能以及白细胞外渗并非必需。 | Schoon, R. M. | PDF | N/A | VE-cadherin RGD motifs are dispensable for cell-cell junctions, endothelial barrier function and leukocyte extravasation | | 分泌型卷曲相关蛋白1a(Secreted Frizzled-Related Protein 1a)以剂量依赖的方式调节造血发育。 | Ide, A. D. | PDF | N/A | Secreted Frizzled-Related Protein 1a regulates hematopoietic development in a dose-dependent manner | | 通过分析差异生长模式来解决前脑发育组织的问题 | Manning, E. | PDF | N/A | Resolving forebrain developmental organisation by analysis of differential growth patterns | | 性染色体和染色体重排是导致Jaera albifrons海洋等足类动物行为性隔离的关键因素。 | Ribardiere, A. | PDF | N/A | Sex chromosomes and chromosomal rearrangements are key to behavioural sexual isolation in Jaera albifrons marine isopods | | 对秀丽隐杆线虫减数分裂过程中链入侵的动力学分析揭示了姐妹染色单体和同源染色体导向修复的速率相似。 | Hamrick, A. | PDF | N/A | Kinetic analysis of strand invasion during C. elegans meiosis reveals similar rates of sister- and homolog-directed repair | | 使用协作交叉(Collaborative Cross)推导小家鼠(Mus musculus)心脏参考范围及新心脏模型的鉴定 | Threadgill, D. W. | PDF | N/A | Derivation of cardiac reference ranges for Mus musculus using the Collaborative Cross and identification of new cardiac models | | 简单DNA重复序列的内在稳定性塑造了重复长度在进化中的稳定分布 | McGinty, R. J. | PDF | N/A | Inherent instability of simple DNA repeats shapes an evolutionarily stable distribution of repeat lengths | | “我们所有人”研究计划中的次大陆遗传多样性:对生物医学研究的影响
在这段翻译中,“Subcontinental”指的是次大陆,通常指印度次大陆;“Genetic Diversity”意为遗传多样性;“All of Us Research Program”是一个特定的研究计划名称,直译为“我们所有人”研究计划;“Implications for Biomedical Research”表示对生物医学研究的影响或意义。整段话的意思是探讨在“我们所有人”研究计划中,次大陆的遗传多样性对生物医学研究可能产生的影响或重要性。 | Gouveia, M. H. | PDF | N/A | Subcontinental Genetic Diversity in the All of Us Research Program: Implications for Biomedical Research | | 通过状态特异性相互作用映射癌症基因动态 | Maqueda Real, A. | PDF | N/A | Mapping cancer gene dynamics through state-specific interactions | | 分子重新适应:啮齿动物中GC偏向基因转换的有害事件后的补偿性进化 | Riffis, M. | PDF | N/A | Molecular re-adaptation: compensatory evolution following deleterious episodes of GC-biased gene conversion in rodents | | TREK K2P通道中非典型电压门控的原子机制 | Sun, H. | PDF | N/A | Atomistic Mechanism of Non-Canonical Voltage Gating in TREK K2P Channels | | 最小侵入性DNA介导的光稳定化技术用于扩展单分子和超分辨率成像 | Scheckenbach, M. | PDF | N/A | Minimally Invasive DNA-Mediated Photostabilization for Extended Single-Molecule and Super-resolution Imaging | | 以下是这段文字的中文翻译:
关于冠状病毒HKU5通过ACE2受体识别的跨物种传播的分子机制研究
翻译解释: - "Molecular Insights" 翻译为 "分子机制研究",表示从分子层面深入探讨。 - "Cross-Species Spillover" 翻译为 "跨物种传播",指病毒从一种物种传播到另一种物种的过程。 - "Coronavirus HKU5" 直接保留为 "冠状病毒HKU5",因为这是特定病毒的名称。 - "via ACE2 Receptor Recognition" 翻译为 "通过ACE2受体识别",表示病毒通过识别ACE2受体实现传播。
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