BioRxiv 2025-01-12 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 无监督无参考推断揭示了人类单细胞中未被识别的受调控转录组复杂性。 | Dehghannasiri, R. | N/A | Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells | |
| 自动多感官整合遵循主观信心而非客观表现 | Gao, Y. | N/A | Automatic multisensory integration follows subjective confidence rather than objectiveperformance | |
| 原核代谢体的结构架构揭示了介导多种蛋白质-蛋白质相互作用的保守界面 | Bhattacharyya, S. | N/A | Structural architecture of a prokaryotic metabolon reveals conserved interfaces mediating multiple protein-protein interactions | |
| 饮食蛋白质来源改变肠道微生物群的组成和功能 | Blakeley-Ruiz, J. A. | N/A | Dietary protein source alters gut microbiota composition and function | |
| 皮层对层次节奏的跟踪协调了生物运动的多感官处理 | Shen, L. | N/A | Cortical tracking of hierarchical rhythms orchestrates the multisensory processing of biological motion | |
| APOE3-R136S突变通过抑制cGAS-STING-IFN通路，赋予了对tau病理的抵抗力。 | Naguib, S. A. | N/A | APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition | |
| 核内Argonaute蛋白NRDE-3在胚胎发育过程中切换小RNA伙伴，以介导时间特异性的基因调控活性。 | Chen, S. | N/A | Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity | |
| 脂质膜对RNA催化活性和稳定性的影响 | Czerniak, T. | N/A | Effects of lipid membranes on RNA catalytic activity and stability | |
| 量化野猪互动以构建疾病传播网络 | Proboste, T. | N/A | Quantifying Feral Pig Interactions to Inform Disease Transmission Networks | |
| TWINKLE：一款用于教学和研究的开源双光子显微镜 | Schottdorf, M. | N/A | TWINKLE: An open-source two-photon microscope for teaching and research | |
| 小脑性伸手共济失调对运动学和动力学需求的敏感性 | Oh, K. | N/A | Sensitivity of Cerebellar Reaching Ataxia to Kinematic and Dynamic Demands | |
| DNA复制叉速度在皮层神经发生中充当引擎 | Wang, J. | N/A | DNA replication fork speed Acts as an Engine in Cortical Neurogenesis | |
| 一种新型的RyR2选择性稳定剂可在不影响心脏功能的情况下预防应激诱导的室性心动过速 | Kurebayashi, N. | N/A | A novel RyR2-selective stabilizer prevents stress-induced ventricular tachycardia without compromising cardiac function | |
| Vγ1+ γδ T细胞来源的IL-4启动CD8 T细胞免疫 | Le, S. | N/A | Vgamma1+ gammadelta T cell-derived IL-4 initiates CD8 T cell immunity | |
| 食品来源的化合物延长冷冻人乳的保质期 | Silpe, J. E. | N/A | Food-Derived Compounds Extend the Shelf-Life of Frozen Human Milk | |
| 一种用于预测蛋白质内在无序区域相互作用的深度学习方法 | Majila, K. | N/A | A deep learning method for predicting interactions for intrinsically disordered regions of proteins | |
| Nurr1调控屏状核的发育与功能 | Yan, K. | N/A | Nurr1 orchestrates claustrum development and functionality | |
| 动态转录组重塑揭示人类神经祖细胞在视网膜色素变性模型中保护视力的机制 | Shahin, S. | N/A | Dynamic Transcriptomic Remodeling in Human Neural Progenitor Cells Reveals Mechanisms for Vision Preservation in Retinitis Pigmentosa Model | |
| 阻塞性睡眠呼吸暂停中的脂肪细胞醛固酮 | Dong, Y. | N/A | Adipocyte Aldosterone in Obstructive Sleep Apnea | |
| Tke5是一种新型的恶臭假单胞菌毒素，它能够使膜去极化，从而杀死植物病原体。 | Velazquez, C. | N/A | Tke5 is a novel Pseudomonas putida toxin that depolarises membranes killing plant pathogens | |
| 将bovicin HC5和ε-聚赖氨酸对橙汁中耐酸热芽孢杆菌（Alicyclobacillus acidoterrestris）的联合效应翻译成中文为：bovicin HC5和ε-聚赖氨酸对橙汁中耐酸热芽孢杆菌的联合效应。 | Iduu, N. V. | N/A | Combinatorial effects of bovicin HC5 and epsilon-polylysine against Alicyclobacillus acidoterrestris in orange juice | |
| 使用牛津纳米孔技术（ONT）进行超短DNA测序的高性能协议 | Zemaitis, L. | N/A | High Performance protocol for ultra-short DNA sequencing using Oxford Nanopore Technology (ONT) | |
| SAPID：一种深入分析植物提取物味道的策略。应用于Swertia chirayita (Roxb.) H.Karst.的复杂味道。 | Rutz, A. | N/A | SAPID: a Strategy to Analyze Plant Extracts Taste In Depth. Application to the complex tasteof Swertia chirayita (Roxb.) H.Karst. | |
| 以下是这段文字的中文翻译： |
从低成本生态计数数据中检测种群趋势的变化 | Singer, L. | PDF | N/A | Testing for changes in population trends from low-cost ecological count data | | 拟南芥基因组-环境关联的实验验证 | Luo, Y. | PDF | N/A | Experimental validation of genome-environment associations in Arabidopsis | | 多变量孟德尔随机化调整遗传混杂因素，分析C反应蛋白对多种疾病的因果影响。 | Shi, R. | PDF | N/A | Multivariable Mendelian Randomization adjusting for heritable confounding analyzes the causal effects of C-reactive protein on multiple diseases | | 昆虫病原性线虫Steinernema hermaphroditum及其共生细菌的基因组 | Schwarz, E. M. | PDF | N/A | Genomes of the entomopathogenic nematode Steinernema hermaphroditum and its associated bacteria | | 通过随机诱变方法提高锌金属蛋白酶的酶效率：突变体酶学及结构特性的研究 | Srivastava, N. | PDF | N/A | Improvement in the enzymatic efficiency of a zinc metalloprotease through random mutagenesis approach: Studies on the enzymatic and structural properties of the mutant | | 胆汁酸敏感离子通道通过跨膜结构域中依赖Ca2+的构象变化来开启。 | Freitas, M. M. | PDF | N/A | The bile acid-sensitive ion channel is gated by Ca2+-dependent conformational changes in the transmembrane domain | | 胶原水凝胶管微生物反应器用于细胞和组织制造 | Yang, Y. | PDF | N/A | Collagen Hydrogel Tube Microbioreactors for Cell and Tissue Manufacturing | | 基于动态规范的灵长类听觉皮层中声音身份的编码 | Esposito, Y. | PDF | N/A | Dynamic Norm-Based Coding of Vocal Identity in the Primate Auditory Cortex | | Drosophila littoralis 昼夜节律与光周期纬度梯度之间的相关性 | Manoli, G. | PDF | N/A | Correlation between circadian and photoperiodic latitudinal clines in Drosophila littoralis | | pH调节提高了抑制性柳枝稷水解产物中的生物燃料产量 | Barten, L. M. | PDF | N/A | pH adjustment increases biofuel production from inhibitory switchgrass hydrolysates | | 厌氧甲烷氧化过程中关键酶MCR的原子分辨率结构揭示了新颖且广泛的翻译后修饰。 | Müller, M.-C. | PDF | N/A | Atomic resolution structures of key enzyme MCR in anaerobic methanotrophy reveal novel and extensive post-translational modifications. | | 逆转录病毒Gag凝聚体与转录爆发位点新生病毒RNA的动态相互作用：对基因组RNA包装的影响 | Kaddis Maldonado, R. J. | PDF | N/A | Dynamic interactions of retroviral Gag condensates with nascent viral RNA at transcriptional burst sites: implications for genomic RNA packaging | | 肠道微生物组中的表观遗传相位变异增强了细菌的适应性 | Ni, M. | PDF | N/A | Epigenetic phase variation in the gut microbiome enhances bacterial adaptation | | 以下是这段英文的中文翻译：
"禁食后屠宰期间荷斯坦×安格斯杂交牛胃肠道微生物群的特征分析"
翻译说明： - Characterization：特征分析，指对某事物进行详细描述和分析。 - Gastrointestinal Tract：胃肠道，指动物的消化系统。 - Holstein x Angus Cross Cattle：荷斯坦×安格斯杂交牛，指荷斯坦奶牛与安格斯肉牛的杂交品种。 - Microbiome：微生物群，指生活在特定环境中的微生物群落。 - During Harvest after Feed Withdrawal：禁食后屠宰期间，指在停止喂食后到屠宰这一时间段。
希望这个翻译对你有帮助！如果有其他问题，欢迎随时提问。 | Costello, M. K. | PDF | N/A | Characterization of the Gastrointestinal Tract Holstein x Angus Cross Cattle Microbiome During Harvest after Feed Withdrawal | | 一种双特异性抗体克服了先前策略的局限性，实现了有效且肿瘤选择性的死亡受体5（DR5）聚集。 | Goldmacher, V. S. | PDF | N/A | A bispecific antibody overcomes limitations of prior strategies to achieve effective and tumor-selective Death Receptor 5 (DR5) clustering | | 由于自噬流受损，细胞外基质机械信号（失调）调节代谢氧化还原稳态。 | Gerardo, H. | PDF | N/A | Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux | | 节点信号（Nodal）与Wnt信号之间的时间协调控制着哺乳动物体型的形成。 | Dias, A. | PDF | N/A | A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan | | 从时间序列推断微生物群落中的资源竞争 | Chen, X. | PDF | N/A | Inferring resource competition in microbial communities from time series | | 温带热浪对昆虫活动昼夜节律的影响：跨栖息地的比较 | Carter, J. | PDF | N/A | Effects of a temperate heatwave on diel rhythms of insect activity: a comparison across habitats | | 宿主回避和抗性各自独立变化，并且对寄生虫基因型具有特异性。 | Amoroso, C. R. | PDF | N/A | Host avoidance and resistance vary independently and are specific to parasite genotype | | 翻转一些变异最慢基因组的开关：在msh1突变体中直接测量植物线粒体和质体突变率 | Broz, A. K. | PDF | N/A | Flipping the switch on some of the slowest mutating genomes: Direct measurements of plant mitochondrial and plastid mutation rates in msh1 mutants | | 人类三维染色质对与心脏病相关的转录因子的剂量依赖性敏感性 | Grant, Z. L. | PDF | N/A | Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor | | 手动与自动注释转座子元素的比较：以果蝇（Drosophila melanogaster）和白纹伊蚊（Aedes albopictus）为例，平衡准确性与生物学相关性 | Carrasco-Valenzuela, T. | PDF | N/A | Manual versus automatic annotation of transposable elements: case studies in Drosophila melanogaster and Aedes albopictus, balancing accuracy and biological relevance | | 一种新型广谱抗生素通过双结合靶点针对多重耐药细菌，且未检测到耐药性。 | He, W. | PDF | N/A | A novel broad-spectrum antibiotic targets multiple-drug-resistant bacteria with dual binding targets and no detectable resistance | | 使用超声波进行微气泡液滴的可编程组装与操控 | Fonseca, A. D. C. | PDF | N/A | Programmable Assembly and Steering of Microbubble Droplets using Ultrasound | | TFBSFootprinter：一种用于预测脊椎动物物种中转录因子结合位点的多组学工具 | Barker, H. | PDF | N/A | TFBSFootprinter: a multiomics tool for prediction of transcription factor binding sites in vertebrate species | | 内在神经时间尺度如何与事件相关活动相关联——柱内连接的关键作用 | Catal, Y. | PDF | N/A | How Intrinsic Neural Timescales Relate To Event-Related Activity - Key Role For Intracolumnar Connections | | 跨前额叶皮层和纹状体的基于模型和无模型强化学习的神经特征 | Miranda, B. | PDF | N/A | Neural signatures of model-based and model-free reinforcement learning across prefrontal cortex and striatum | | 改变的微小RNA表达与由多微生物感染引起的TLR2/4依赖性牙周炎症和骨吸收减少相关 | Jeepipalli, S. | PDF | N/A | Altered microRNA Expression Correlates with Reduced TLR2/4-Dependent Periodontal Inflammation and Bone Resorption Induced by Polymicrobial Infection | | 胆固醇缺乏引导自噬依赖性细胞外囊泡的分泌 | Yaeger, J. D. | PDF | N/A | Cholesterol deficiency directs autophagy-dependent secretion of extracellular vesicles | | 身体活动与久坐刺激的趋近与回避倾向的神经相关性：一项功能性磁共振成像研究 | Cheval, B. | PDF | N/A | Neural correlates of approach and avoidance tendencies toward physical activity and sedentary stimuli: An fMRI study | | 单胺诱导的二酰甘油信号迅速在纳米簇中积累Unc13，以实现快速的突触前增强。 | Blaum, N. | PDF | N/A | Monoamine-induced diacylglycerol signaling rapidly accumulates Unc13 in nanoclusters for fast presynaptic potentiation | | OPTN保护视网膜神经节细胞并改善视神经病变中的神经炎症。 | Wang, Q. | PDF | N/A | OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies | | 经颅磁刺激（TMS）诱发电位对皮层中电场方向的依赖性 | Grano, I. | PDF | N/A | The dependency of TMS-evoked potentials on electric-field orientation in the cortex | | 使用脑电图超扫描技术对石头剪刀布竞争决策的神经解码 | Moerel, D. | PDF | N/A | Neural decoding of competitive decision-making in Rock-Paper-Scissors using EEG hyperscanning | | 转基因A53T小鼠的多巴胺和纹状体区域存在星形胶质细胞的α-突触核蛋白聚集。 | Peat, C. | PDF | N/A | Transgenic A53T mice have astrocytic α-synuclein aggregates in dopamine and striatal regions | | 理解超声波神经调控的高阶网络可塑性机制 | Gatica, M. | PDF | N/A | Understanding the high-order network plasticity mechanisms of ultrasound neuromodulation | | 长期在果蝇中进行多通道记录的研究揭示，与清醒状态相比，果蝇在睡眠期间对异常视觉刺激的反应存在显著差异。 | van Swinderen, B. | PDF | N/A | Long-term multichannel recordings in Drosophila flies reveal distinct responses to deviant visual stimuli during sleep compared to wake | | 增强老年人和听力损失患者的神经语音追踪：随机共振的作用 | Herrmann, B. | PDF | N/A | Enhanced Neural Speech Tracking in Aging and Hearing Loss: The Role of Stochastic Resonance | | 鉴定人类细胞中复制应激反应的关键因素 | Janssen, L. M. E. | PDF | N/A | Identification of critical factors of the replication stress response in human cells | | 肌球蛋白-IC（Myosin-IC）的高分辨率结构揭示了一种独特的肌动蛋白结合方向、ADP释放途径以及动力冲程轨迹。 | Chavali, S. S. | PDF | N/A | High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory | | 巨型KASH蛋白与核糖体协同作用在体内建立细胞质生物物理特性 | Ding, X. | PDF | N/A | Giant KASH proteins and ribosomes synergistically establish cytoplasmic biophysical properties in vivo | | 竞争性信号通路控制电趋化 | Kulkarni, S. | PDF | N/A | Competing signaling pathways controls electrotaxis | | 通过高时间分辨率的荧光寿命光度法对快速和慢速神经元信号进行绝对测量 | Lodder, B. | PDF | N/A | Absolute measurement of fast and slow neuronal signals with fluorescence lifetime photometry at high temporal resolution | | 通过cryoCLEM引导的cryoET技术可视化的记忆印迹突触的三维分子结构 | Lovatt, C. | PDF | N/A | Memory engram synapse 3D molecular architecture visualized by cryoCLEM-guided cryoET | | PKD3定位于晚期内体，以维持依赖于Rab7的内溶酶体稳态。 | Gutierrez-Galindo, E. | PDF | N/A | PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomalhomeostasis | | 扩展了明亮且光稳定的细胞器钙离子传感器的调色板 | Moret, A. | PDF | N/A | An expanded palette of bright and photostable organellar Ca2+ sensors | | 基于图像的筛选识别内源性Dvl2生物分子凝聚体的调控因子 | Schubert, A. | PDF | N/A | Image-based screens identify regulators of endogenous Dvl2 biomolecular condensates | | 睡眠增加了大脑生理脉动的传播速度 | Elabasy, A. | PDF | N/A | Sleep increases propagation speed of physiological brain pulsations | | 从区域脑剖面构建结构和功能脑网络 | Song, D. | PDF | N/A | Constructing structural and functional brain networks from regional brain profiles | | 通过背侧前扣带回克服骄傲是接受不公平提议的基础 | Numano, S. | PDF | N/A | Overcoming pride via the dorsal ACC underlies acceptance of unfair offers | | 自动暗示和心理意象对社会情绪感知的偏见 | Myga, K. A. | PDF | N/A | Autosuggestion and Mental Imagery Bias the Perception of Social Emotions | | 阿普唑仑诱导雌性小鼠情境恐惧记忆的顺行性遗忘并改变背腹侧海马神经元群体活动。 | Kaplan, K. | PDF | N/A | Alprazolam induces anterograde amnesia for contextual fear memory and alters dorsoventral hippocampal neuronal ensembles in female mice | | 体育锻炼恢复由非严重性鼠疟疾破坏的神经认知稳态 | de Sousa, L. P. | PDF | N/A | PHYSICAL EXERCISE RESTORES NEUROCOGNITIVE HOMEOSTASIS DISRUPTED BY NON-SEVERE MURINE MALARIA | | 人类中缝背核活动信号行为策略的变化 | Priestley, L. | PDF | N/A | ACTIVITY IN HUMAN DORSAL RAPHE NUCLEUS SIGNALS CHANGES IN BEHAVIOURAL POLICY | | 基于尖峰时间响应曲线的脉冲耦合振荡器的平均场理论 | Canavier, C. C. | PDF | N/A | A Mean Field Theory for Pulse-Coupled Oscillators based on the Spike Time Response Curve | | 交感神经轴突的再生失败是导致神经损伤后功能恢复缺陷的原因之一。 | Tian, T. | PDF | N/A | Regenerative failure of sympathetic axons contributes to deficits in functional recovery after nerve injury | | 射血分数保留型心力衰竭中血管对认知障碍的贡献：TRPV4和KLF2作为ZSF1模型中神经血管功能障碍的关键介质 | Lambrichts, S. M. P. | PDF | N/A | Vascular contribution to cognitive impairment in heart failure with preserved ejection fraction: TRPV4 and KLF2 as key mediators of neurovascular dysfunction in the ZSF1 model | | 来自心肌梗死模型的透明大鼠心脏中胶原纤维的深层组织二次谐波 | Matsuyama, M. | PDF | N/A | Deep Tissue Second-Harmonics of Collagen Fibers in a Transparent Rat Heart from a Myocardial Infarction Model | | 建立一个临床前慢性伤口模型以表征蛇咬伤中毒的病理生理学 | Dawson, C. A. | PDF | N/A | Establishing a preclinical chronic wound model to characterise the pathophysiology of snakebite envenoming | | 正弦调节去噪昼夜节律机制 | Kaji, H. | PDF | N/A | Sinusoidal regulation denoises circadian machinery | | 生物膜基质保护枯草芽孢杆菌免受过氧化氢的侵害。 | Muratov, E. | PDF | N/A | The biofilm matrix protects Bacillus subtilis against hydrogen peroxide | | 皮质类固醇耐药性在急性移植物抗宿主病（Graft Versus Host Disease, GVHD）发作时由早期免疫反应动态预先决定。 | Le Grand, S. | PDF | N/A | Corticosteroid resistance is predetermined by early immune response dynamics at acute Graft Versus Host disease onset | | 在协作交叉小鼠品系中进行遗传定位，识别出影响可卡因初始敏感性的基因位点。 | Schoenrock, S. A. | PDF | N/A | Genetic mapping in Collaborative Cross mouse strains identifies loci that affect initial sensitivity to cocaine | | 稀疏测序技术允许对全基因组范围内的胞嘧啶修饰水平进行精确且高效的量化。 | Loo, C. E. | PDF | N/A | Sparse Sequencing permits accurate and efficient quantification of genome-wide cytosine modification levels |