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BioRxiv 2025-01-16 Papers

标题 作者 PDF链接 代码仓库 Title
在由蛋白质聚集体引起的应激条件下,蛋白酶体通过扩散和依赖细胞骨架的机制进行重新分布。 Morten, M. J. PDF N/A Redistribution of proteasomes through diffusion and cytoskeleton-dependent mechanisms upon stress induced by protein aggregates
SRSF3是心外膜形成的关键调控因子。 Lupu, I.-E. PDF N/A SRSF3 is a key regulator of epicardial formation
无尺度模型下的染色体结构、动力学与力学研究 Grosse-Holz, S. PDF N/A Scale-free models of chromosome structure, dynamics, and mechanics
在非快速眼动睡眠期间进行的目标记忆重新激活是否需要互补的快速眼动睡眠以促进记忆巩固? Sifuentes Ortega, R. PDF N/A Does targeted memory reactivation during NREM sleep require complementary REM sleep for memory consolidation?
以下是这段英文的中文翻译:

证据表明,通过合成的自体四倍体秀丽隐杆线虫(Caenorhabditis elegans)可以增强抗逆性,这与多倍体化有关。

翻译说明: - polyploidy:多倍体化,指细胞或生物体含有超过两套染色体的现象。 - synthetic autotetraploid:合成的自体四倍体,指通过人工方法使生物体成为四倍体。 - Caenorhabditis elegans:秀丽隐杆线虫,一种常用于生物学研究的模式生物。 - stress resistance:抗逆性,指生物体对环境压力(如高温、干旱等)的耐受能力。 | Chauve, L. | PDF | N/A | Evidence for increased stress resistance due to polyploidy from synthetic autotetraploid Caenorhabditis elegans | | 感知觉意识的突发依赖性丘脑皮质基础 | Whyte, C. J. | PDF | N/A | A Burst-dependent Thalamocortical Substrate for Perceptual Awareness | | 变态过程逆转了Rana arvalis(一种蛙类)沿纬度梯度的行为表型。 | Cortazar-Chinarro, M. | PDF | N/A | Metamorphosis reverses the behavioural phenotype in Rana arvalis along a latitudinal gradient | | 西南太平洋地区花朵大小的演化 | Ciarle, R. | PDF | N/A | Flower size evolution in the Southwest Pacific | | 高强度任务切换训练与单一任务训练对儿童认知控制的行为和神经表现有不同的影响 | Schwarze, S. A. | PDF | N/A | Intensive task-switching training and single-task training differentially affect behavioral and neural manifestations of cognitive control in children | | 组蛋白H2A.Z去乙酰化与心肌梗死/Tip60缺失心肌细胞的去分化 | Wang, X. | PDF | N/A | Histone H2A.Z Deacetylation and Dedifferentiationin Infarcted/Tip60-depleted Cardiomyocytes | | 识别针对人类TRPM4的小分子抑制剂的结合位点 | Ekundayo, B. | PDF | N/A | Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4 | | 亚历山大病蛋白GFAP驱动线粒体分裂 | XIONG, D. | PDF | N/A | The Alexander Disease Protein GFAP Drives Mitochondrial Fission | | 将这段翻译成中文如下:

基于仿生透明质酸支架的导电MXene基微网格3D打印技术,用于引导和增强神经修复应用中的电刺激。

解释: - 3D-Printing:3D打印 - Electroconductive:导电的 - MXene-based:基于MXene的(MXene是一种二维材料) - Micro-meshes:微网格 - Biomimetic:仿生的 - Hyaluronic Acid-based Scaffold:基于透明质酸的支架 - Directs and Enhances:引导和增强 - Electrical Stimulation:电刺激 - Neural Repair Applications:神经修复应用

整体翻译为:基于仿生透明质酸支架的导电MXene基微网格3D打印技术,用于引导和增强神经修复应用中的电刺激。 | Woods, I. | PDF | N/A | 3D-Printing of Electroconductive MXene-based Micro-meshes in a Biomimetic Hyaluronic Acid-based Scaffold Directs and Enhances Electrical Stimulation for Neural Repair Applications. | | 剪接因子激酶SRPK1是外周血管疾病的治疗靶点。 | Bhalla, S. R. | PDF | N/A | The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease | | 动物起源时期大量外包高能耗氨基酸 | Kasalo, N. | PDF | N/A | Massive outsourcing of energetically costly amino acids at the origin of animals | | Rudhira介导的微管稳定性控制小鼠血管发育过程中的TGFβ信号传导 | Joshi, D. | PDF | N/A | Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development | | 沙眼衣原体的T3SS结构和效应基因在不同的表型细胞形式中表达。 | Grieshaber, N. | PDF | N/A | The T3SS structural and effector genes of Chlamydia trachomatis are expressed in distinct phenotypic cell forms. | | 对烟曲霉小RNA生成机制的研究揭示了双链RNA依赖的生长停滞证据。 | Kelani, A. A. | PDF | N/A | Investigation of Aspergillus fumigatus small RNA biogenesis uncovers evidence of double-stranded RNA-dependent growth arrest. | | 对秀丽隐杆线虫(C. elegans)中Smad和Schnurri转录因子的全基因组分析表明,它们之间存在广泛的相互作用,并在胶原蛋白分泌中发挥功能。 | Vora, M. | PDF | N/A | Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion | | 以下是这段文字的中文翻译:

山兔(Lepus timidus)染色体水平参考基因组组装

翻译说明: - "Chromosome-level" 译为“染色体水平”,表示基因组的组装精度达到了染色体级别。 - "reference genome assembly" 译为“参考基因组组装”,指的是作为标准参考的基因组序列。 - "mountain hare" 译为“山兔”,是 Lepus timidus 的常见中文名称。

希望这对你有帮助! | Fekete, Z. | PDF | N/A | Chromosome-level reference genome assembly for the mountain hare (Lepus timidus) | | 藻际圈挥发性有机化合物专家 | Padaki, V. G. | PDF | N/A | Volatile Organic Compound Specialists in the Phycosphere | | CA1锥体神经元和轴突-轴突细胞之间的相互交互控制着尖波-涟漪事件 | Gilbert, E. T. | PDF | N/A | Reciprocal interactions between CA1 pyramidal and axo-axonic cells control sharp wave-ripple events | | 微囊藻中标记基因及细胞内无定形碳酸钙生物矿化候选基因表达的昼夜变化 | Bruley, A. | PDF | N/A | Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis | | 在霍乱弧菌生物膜中进行细胞尺度的基因表达测量,揭示了其发育过程中的时空模式。 | Johnson, G. E. | PDF | N/A | Cell-scale gene-expression measurements in Vibrio cholerae biofilms reveal spatiotemporal patterns underlying development | | 对所有人类旁系同源基因对进行遗传定位,以表征合成致死性和缓冲效应 | Flister, M. J. | PDF | N/A | Genetic Mapping of All Human Paralog Pairs to Characterize Synthetic Lethality and Buffering | | 一种基于胍的冠状病毒复制抑制剂,该抑制剂针对nsp15内切核糖核酸酶,并选择对干扰素敏感的突变病毒。 | Van Loy, B. | PDF | N/A | A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses | | 以下是这段英文的中文翻译:

扁盘动物分泌细胞类型与摄食、先天免疫和行为调节有关

翻译说明: - Placozoan 指的是“扁盘动物”,一种简单的多细胞生物。 - secretory cell types 指的是“分泌细胞类型”。 - implicated in 表示“与……有关”或“涉及”。 - feeding 是“摄食”。 - innate immunity 是“先天免疫”。 - regulation of behavior 是“行为调节”。

希望这个翻译对你有帮助! | Mayorova, T. D. | PDF | N/A | Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior | | 减少覆盖范围的空间异质性可以提高犬只狂犬病疫苗接种活动的有效性。 | Ferguson, E. | PDF | N/A | Reducing spatial heterogeneity in coverage improves the effectiveness of dog vaccination campaigns against rabies | | 人类和小鼠模型揭示了歌舞伎综合征中抑制性突触发育的增加。 | Knopp, J. | PDF | N/A | Human and Mouse Models for Kabuki Syndrome Reveal Increase in Inhibitory Synapse Development. | | 单细胞RNA测序揭示小鼠动脉粥样硬化过程中外膜成纤维细胞的变化 | Fries, L. E. | PDF | N/A | Single-Cell RNA-Seq Reveals Adventitial Fibroblast Alterations during Mouse Atherosclerosis | | 基于RSPO4的肽体靶向LGR4/5/6的喜树碱类似物缀合物在结直肠癌临床前模型中的抗肿瘤活性。 | Toh, Y. | PDF | N/A | Anti-tumor activity of camptothecin analog conjugate of a RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer. | | 开发和验证用于胶质母细胞瘤治疗的综合肿瘤治疗电场系统:从原型设计到临床前评估

本研究旨在开发和验证一种用于胶质母细胞瘤(GBM)治疗的综合肿瘤治疗电场(TTFields)系统。研究过程涵盖了从原型设计到临床前评估的多个阶段。首先,我们设计了一种新型的TTFields设备原型,该设备能够产生特定频率和强度的交变电场,以抑制肿瘤细胞的增殖并诱导其凋亡。随后,我们对设备进行了优化,确保其在实际应用中的稳定性和安全性。在临床前评估阶段,我们通过体外和体内实验验证了该系统的有效性和生物相容性。实验结果表明,该TTFields系统能够显著抑制胶质母细胞瘤的生长,并延长实验动物的生存期。此外,我们还评估了该系统的安全性,未发现明显的副作用或毒性反应。综上所述,本研究成功开发并验证了一种新型的TTFields系统,为胶质母细胞瘤的治疗提供了新的可能性。 | Wang, X. | PDF | N/A | Development and Validation of a Comprehensive Tumor Treating Fields System for Glioblastoma Therapy: From Prototype Design to Preclinical Evaluation | | 铜绿假单胞菌对VI型分泌系统攻击的抵抗机制 | Tejada-Arranz, A. | PDF | N/A | Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks | | 病毒载体介导的SLC9A6基因替换减轻了Christianson综合征震颤大鼠模型的小脑功能障碍 | Anderson, C. J. | PDF | N/A | Viral vector-mediated SLC9A6 gene replacement reduces cerebellar dysfunction in the shaker rat model of Christianson syndrome | | GCTransNet: 基于全局上下文视觉Transformer的3D线粒体实例分割 | Chen, C. | PDF | N/A | GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers | | 重新定义性传播寄生虫阴道毛滴虫(Trichomonas vaginalis)及其在鸽形目鸟类近亲中的剪接体内含子 | Callejas-Hernandez, F. | PDF | N/A | Redefining the spliceosomal introns of the sexually transmitted parasite Trichomonas vaginalis and its close relatives in columbid birds | | 一项全动物表型药物筛选识别出抑制致动脉粥样硬化脂蛋白的药物 | Kelpsch, D. J. | PDF | N/A | A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins | | 一项全动物表型药物筛选发现了致动脉粥样硬化脂蛋白的抑制剂。 | Kelpsch, D. J. | PDF | N/A | A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins | | 使用MACH2表征转移性癌症迁移历史的解决方案空间 | Roddur, M. S. | PDF | N/A | Characterizing the Solution Space of Migration Histories of Metastatic Cancers with MACH2 | | 时光飞逝:果蝇头部单核RNA测序老化时钟揭示性别差异老化 | Tennant, N. | PDF | N/A | TimeFlies: an snRNA-seq aging clock for the fruit fly head sheds light on sex-biased aging | | 量化单细胞数据中的病理进展 | Khan, S. R. | PDF | N/A | Quantifying Pathological Progression from Single-Cell Data | | 结核分枝杆菌CrgA蛋白形成二聚体结构,其跨膜结构域被夹在细胞质和周围质β-折叠之间,从而能够与其他分裂体蛋白进行多种相互作用。 | Shin, Y. | PDF | N/A | Mycobacterium tuberculosis CrgA Forms a Dimeric Structure with Its Transmembrane Domain Sandwiched between Cytoplasmic and Periplasmic β-Sheets, Enabling Multiple Interactions with Other Divisome Proteins | | 这段英文可以翻译为:

“果胶酸裂解酶样基因在陆地植物中的进化,及其在寄生植物吸器形成中的作用。”

其中,“pectate lyase-like genes”指的是“果胶酸裂解酶样基因”,“land plants”指的是“陆地植物”,“haustorium formation”指的是“吸器形成”,“parasitic plants”指的是“寄生植物”。 | Zhang, H. | PDF | N/A | The evolution of pectate lyase-like genes across land plants, and their roles in haustorium formation in parasitic plants | | 巨噬细胞中的WASp活性通过保护核膜来防止机械诱导的炎症。 | Amadio, R. | PDF | N/A | WASp activity in macrophages prevents mechano-induced inflammation by protecting the nuclear envelope | | YAP通过与RIF1相互作用来缓解鳞状细胞癌中的复制应激。 | Bojko, J. | PDF | N/A | YAP engages RIF1 to dampen replication stress in squamous cell carcinoma. | | 根据英国生物银行(UK Biobank)的序列数据估计,人类基因转换的平均长度约为459个碱基对(bp)。 | Masaki, N. | PDF | N/A | Mean gene conversion tract length in humans estimated to be 459 bp from UK Biobank sequence data | | 促进疼痛通路中Cav3.2通道的门控揭示了血清诱导痛觉过敏的新机制 | Sanner, K. | PDF | N/A | Facilitation of Cav3.2 channel gating in pain pathways reveals a novel mechanism of serum-induced hyperalgesia | | 冠状病毒HKU5通过ACE2受体识别的跨物种传播的分子机制研究 | Xia, L. | PDF | N/A | Molecular Insights into Cross-Species Spillover of Coronavirus HKU5 via ACE2 Receptor Recognition | | 交感神经轴突的再生失败导致神经损伤后功能恢复的缺陷 | Tian, T. | PDF | N/A | Regenerative failure of sympathetic axons contributes to deficits in functional recovery after nerve injury | | 已获许可的治疗药物对Mpox Ib分支的体外抗病毒活性;Mpox治疗的替代方案 | Horton, A. | PDF | N/A | The antiviral activity of licensed therapeutics against Mpox clade Ib, in vitro; alternative options for the treatment of Mpox | | 内源性表达的P2X5包含一部分对细胞外ATP敏感的异构体或转录变体。 | Yang, X.-N. | PDF | N/A | Endogenously expressed P2X5 includes a proportion of isoforms or transcript variants sensitive to extracellular ATP | | 通过有效靶向PI3K激酶,绕过Nrf2过度激活的头颈癌对顺铂的耐药性 | Yadollahi, P. | PDF | N/A | Bypassing cisplatin resistance in Nrf2 hyperactivated head and neck cancer through effective PI3Kinase targeting | | 使用PARTI技术监测细胞内单体特异性酰基-tRNA水平 | Pressimone, M. A. | PDF | N/A | Monitoring monomer-specific acyl-tRNA levels in cells with PARTI | | 在黄杆菌IR1中删除moe A基因会导致结构颜色从绿色转变为蓝色,并改变多糖代谢。 | Escobar Doncel, A. | PDF | N/A | Deletion of the moe A gene in Flavobacterium IR1 drives structural color shift from green to blue and alters polysaccharide metabolism | | 通过整合AlphaFold3和模板信息准确预测蛋白质复合物的化学计量比 | Liu, J. | PDF | N/A | Accurate Prediction of Protein Complex Stoichiometry by Integrating AlphaFold3 and Template Information | | 实验性微生物群移植中细菌和病毒传播的动态 | Weagley, J. | PDF | N/A | Dynamics of Bacterial and Viral Transmission in Experimental Microbiota Transplantation | | 发现并分析了一个841 kbp的噬菌体基因组:迄今为止已知的最大基因组 | CHEN, L. | PDF | N/A | Discovery and analysis of an 841 kbp phage genome: the largest known to date | | 开发一种具有复制能力的小鼠诺如病毒报告系统 | Olson, M. C. | PDF | N/A | Development of a replication competent murine norovirus reporter system | | 定义在委内瑞拉链霉菌中连接RNase III和RNase J介导的初级和次级代谢调控的网络 | Pepler, M. A. D. | PDF | N/A | Defining the networks that connect RNase III and RNase J-mediated regulation of primary and specialized metabolism in Streptomyces venezuelae | | 胎盘疟疾中的多系统失调导致小鼠不良围产期结局 | Ekregbesi, P. | PDF | N/A | Multi-System Dysregulation in Placental Malaria Contributes to Adverse Perinatal Outcomes in Mice | | 在低碳条件下的生长揭示了氨基酸耦合的铁吸收机制 | Lara-Gutierrez, J. | PDF | N/A | Growth in Low Carbon Conditions Reveals Amino-Acid-Coupled Iron Uptake | | Paulinella chromatophore 转运肽的第二部分采用了类似于γ-谷氨酰环转移酶折叠的结构折叠。 | Klimenko, V. | PDF | N/A | The Paulinella chromatophore transit peptide part2 adopts a structural fold similar to the γ-glutamyl-cyclotransferase fold | | 甲氟喹与多粘菌素B联合使用时,能够降低鲍曼不动杆菌的细菌膜流动性,并导致细菌膜变形。 | Tharmalingam, N. | PDF | N/A | Mefloquine reduces the bacterial membrane fluidity of Acinetobacter baumannii and distorts the bacterial membrane when combined with polymyxin B | | DNA编码库筛选揭示出针对隐秘变构结合位点的强效DNMT2抑制剂 | Frey, A. F. | PDF | N/A | DNA-encoded Library Screening Uncovers Potent DNMT2 Inhibitors Targeting a Cryptic Allosteric Binding Site | | 以下是这段英文的中文翻译:

结构基础揭示了驯化的II类内含子样逆转录酶在宿主细胞DNA修复中的功能进化

这个翻译保留了原文的科学性和专业性,同时使中文读者能够理解其含义。 | Park, S. K. | PDF | N/A | Structural basis for the evolution of a domesticated group II intron-like reverse transcriptase to function in host cell DNA repair | | m3C是一种线粒体mRNA修饰,能够促进肿瘤进展。 | Penning, A. | PDF | N/A | m3C is a mitochondrial mRNA modification which promotes tumor progression | | 从宏观到微观:埃及伊蚊的全新基因组使得近缘和远缘物种间的比较基因组学研究成为可能 | Morinaga, G. | PDF | N/A | From macro to micro: De novo genomes of Aedes mosquitoes enable comparative genomics among close and distant relatives | | 利用长读长测序技术在柄孢壳菌(Podospora anserina)中重建具有高度内部保守性的NOD样受体等位基因 | Ament-Velasquez, S. L. | PDF | N/A | Reconstructing NOD-like receptor alleles with high internal conservation in Podospora anserina using long-read sequencing | | 以下是这段英文的中文翻译:

结构机制:泛素连接酶适配蛋白Cyclin F识别E2F1

翻译说明: - "Structural mechanism" 翻译为 "结构机制"。 - "recognition" 翻译为 "识别"。 - "E2F1" 是蛋白质名称,保留不变。 - "ubiquitin ligase adaptor" 翻译为 "泛素连接酶适配蛋白"。 - "Cyclin F" 是蛋白质名称,保留不变。

整句话描述了Cyclin F通过结构机制识别E2F1的过程。 | Ngoi, P. | PDF | N/A | Structural mechanism for recognition of E2F1 by the ubiquitin ligase adaptor Cyclin F | | 通过单结合测定数据直接获取内在协同性α的实验条件,以FKBP12、MAPRE1和大环分子胶的三元复合物形成为例。 | Schnatwinkel, J. | PDF | N/A | Experimental conditions to retrieve intrinsic cooperativity α directly from single binding assay data exemplified by the ternary complex formation of FKBP12, MAPRE1 and macrocyclic molecular glues | | 以下是这段英文的中文翻译:

高分辨率烟草花叶病毒盘状结构通过冷冻电镜获得

这段文字描述了通过冷冻电镜技术获得的高分辨率烟草花叶病毒(Tobacco Mosaic Virus, TMV)盘状结构的研究成果。 | Abu-Baker, I. | PDF | N/A | High-Resolution Structures of Tobacco Mosaic Virus Disks from Cryo-Electron Microscopy | | 揭示盐浓度对嗜盐酶催化循环不同阶段的影响 | Vallejos-Baccelliere, G. | PDF | N/A | Unveiling the influence of salt concentration on the different stages of the catalytic cycle of a halophilic enzyme | | 真核生物和原核生物中用于高效转录后控制的托尔德开关的计算设计 | Landau, Y. | PDF | N/A | Computational design of toehold switches in eukaryotes and prokaryotes for efficient post-transcriptional control | | 弹性蛋白样多肽复合凝聚体的形成与凝胶化 | Fisher, R. S. | PDF | N/A | Formation and Gelation of Elastin-like Polypeptide Complex Coacervates | | 经验指导小鼠视觉皮层关键期可塑性中神经元调谐的不稳定性 | Brown, T. C. | PDF | N/A | Experience directs the instability of neuronal tuning for critical period plasticity in mouse visual cortex | | 皮层传播波可能支撑着人格特质的变异。 | Bailey, N. W. | PDF | N/A | Cortical travelling waves may underpin variation in personality traits | | 应激激活的神经元群在乳头体上核中储存焦虑而非记忆 | Zhang, J. | PDF | N/A | Stress-activated neuronal ensemble in the supramammillary nucleus stores anxiety but not memory | | 培养环境中神经活动高维几何的自组织 | Nakamuta, A. | PDF | N/A | Self-organization of high-dimensional geometry of neural activity in culture | | 评估从以色列沿海水域分离出的弧菌的毒性和竞争适应性 | Kanarek, K. | PDF | N/A | Assessing toxicity and competitive fitness of vibrios isolated from coastal waters in Israel | | 接种一种新型RNA复制子疫苗可在24种鸟类中提供针对H5N1禽流感病毒的长期保护。 | Zimmer, G. | PDF | N/A | Immunization with a novel RNA replicon vaccine confers long-lasting protection against H5N1 avian influenza virus in 24 bird species | | 识别出一种来自脆弱拟杆菌(Bacteroides fragilis)的分泌性蛋白酶,该酶通过切割蛋白酶激活受体2(PAR2)引发肠道疼痛和炎症。 | Lakemeyer, M. | PDF | N/A | Identification of a secreted protease from Bacteroides fragilis that induces intestinal pain and inflammation by cleavage of PAR2 | | 通过对婴儿粪便中链球菌菌株在人体各部位的追踪研究,发现肠道特异性与粘附素有关。 | Ormaasen, I. | PDF | N/A | Tracing of streptococcal strains from infant stool across human body sites links gut-specificity to adhesins | | 组蛋白修饰调节因子SIN3在细胞对糖酵解通量变化的响应中发挥作用。 | Soukar, I. | PDF | N/A | The histone modification regulator, SIN3, plays a role in the cellular response to changes in glycolytic flux | | 从土壤环境DNA解读景观尺度植物覆盖与生物多样性 | Goodall, T. I. | PDF | N/A | Deciphering landscape-scale plant cover and biodiversity from soil eDNA | | 墨尔本病毒编码一种较短的H2B-H2A双联组蛋白变体,这种变体能够形成结构上独特的核小体结构。 | Villalta, A. | PDF | N/A | Melbournevirus encodes a shorter H2B-H2A doublet histone variant that forms structurally distinct nucleosome structures. | | 以下是这段英文的中文翻译:

DSB诱导后染色体丢失频率的定量分析

翻译说明: - "Quantitative analysis" 翻译为 "定量分析" - "frequency" 翻译为 "频率" - "chromosome loss" 翻译为 "染色体丢失" - "DSB induction" 翻译为 "DSB诱导"(DSB指DNA双链断裂)

希望这个翻译对你有帮助! | Matsuno, S. | PDF | N/A | Quantitative analysis of the frequency of chromosome loss following DSB induction | | 个体发育驱动Gata1突变的阶段特异性效应 | Sommer, A. | PDF | N/A | Ontogeny drives stage-specific effects of a Gata1 mutation | | 酵母DNA聚合酶δ的校对核酸酶抑制跨损伤合成并促进DNA损伤旁路中的重组。 | Jun, C. | PDF | N/A | Yeast DNA Polymerase δ Proofreading Nuclease Suppresses Translesion Synthesis and Facilitates Recombination in DNA Lesion Bypass. | | 通过原生金属蛋白质组学检测铜绿假单胞菌中的铁蛋白超级复合物 | Saito, M. | PDF | N/A | Detection of Iron Protein Supercomplexes in Pseudomonas aeruginosa by Native Metalloproteomics | | 使用幂律特征从单样本单细胞RNA测序数据中识别记忆基因表达 | Ghosh, S. | PDF | N/A | Identifying memory gene expression from single sample scRNA-seq data using power law signatures | | 标题:在USDA 110型慢生根瘤菌(Bradyrhizobium diazoefficiens)从浮游状态向生物膜状态转变过程中Tad菌毛的作用

内容翻译: 本研究探讨了USDA 110型慢生根瘤菌(Bradyrhizobium diazoefficiens)在从浮游生长状态向生物膜形成状态转变过程中,Tad菌毛所扮演的角色。Tad菌毛是一种细胞表面附属结构,已知在多种细菌的黏附、聚集及生物膜形成中起关键作用。通过一系列遗传和表型分析,我们发现Tad菌毛对于USDA 110型菌株在固体表面上的初期附着和生物膜结构的建立至关重要。缺乏Tad菌毛的突变体表现出显著的生物膜形成缺陷,这强调了这些结构在细菌群落生活方式中的重要性。此外,我们的研究还揭示了Tad菌毛在调节细胞间相互作用和环境适应性中的潜在机制,为理解慢生根瘤菌的生态适应性和生物膜相关功能提供了新的见解。 | Iglesias, J. A. | PDF | N/A | Role of Tad Pili during the transition from Planktonic to Biofilm State in Bradyrhizobium diazoefficiens USDA 110 | | 探索古代粪便中的病原体谱 | Capone, D. | PDF | N/A | Exploring the Pathogen Profiles of Ancient Feces | | 单细胞RNA测序揭示了克氏锥虫群体中类转唾液酸酶超家族基因的表达异质性 | Inchausti, L. | PDF | N/A | Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations | | 妇科癌症中免疫检查点抑制剂反应的代谢特征:基于通量平衡分析的见解 | Idumah, G. | PDF | N/A | Metabolic Signatures of Immune Checkpoint Inhibitor Response in Gynecologic Cancers: Insights from Flux Balance Analysis | | 以下是这段英文的中文翻译:

临床和分类学特征:一种新型尿路病原体——兰州普罗维登斯菌

翻译说明: - "Clinical and Taxonomic Characterization" 翻译为 "临床和分类学特征"。 - "Novel" 翻译为 "新型"。 - "Urinary Tract Pathogen" 翻译为 "尿路病原体"。 - "Providencia lanzhouensis" 是细菌的学名,直接保留原文,翻译为 "兰州普罗维登斯菌"。

希望这个翻译对你有帮助! | Xiang, Y. | PDF | N/A | Clinical and Taxonomic Characterization of a Novel Urinary Tract Pathogen Providencia lanzhouensis | | 一个简单、低成本且高效的从人血中快速分离致病菌的协议 | Coskun, F. S. | PDF | N/A | A Simple, Low-Cost, and Efficient Protocol for Rapid Isolation of Pathogenic Bacteria from Human Blood | | 处于接受端的女性:探索尼日利亚夫妇不孕不育挑战的经历 | Esan, D. T. | PDF | N/A | Women at the receiving end: Exploring Couples' experiences of infertility challenges in Nigeria | | 与Heliconiini(一种蝴蝶)多次向群居幼虫行为转变相关的趋同分子进化 | Cicconardi, F. | PDF | N/A | Convergent molecular evolution associated with repeated transition to gregarious larval behaviour in Heliconiini | | 迈向高精度的参考和方法选择,实现跨数据集的通用细胞类型注释 | Shen, Q. | PDF | N/A | Toward highly accurate reference and method selection for universal cross-dataset cell type annotation | | 芳樟醇和反式橙花叔醇可预防成年斑马鱼因戊四氮引发的癫痫发作。 | Silva, A. L. | PDF | N/A | Linalool and trans-nerolidol prevent pentylenetetrazole-induced seizures in adult zebrafish | | 行为解码揭示了小鼠癫痫微特征及其相关的猝死风险 | Shen, Y. | PDF | N/A | Behavior decoding delineates seizure microfeatures and associated sudden death risks in mice | | 增强的促惊厥敏感性,而非自发的快速游泳活动,是稳定突变体和表达GCaMP6s的F0 crispant低色素斑马鱼中scn1lab功能丧失的显著相关特征。 | McGraw, C. M. | PDF | N/A | Enhanced proconvulsant sensitivity, not spontaneous rapid swimming activity, is a robust correlate of scn1lab loss-of-function in stable mutant and F0 crispant hypopigmented zebrafish expressing GCaMP6s | | 对单细胞RNA测序(scRNA-seq)数据中的自动化癌细胞注释方法进行基准测试,揭示了共识注释作为首选方法。 | Abdelaal, T. | PDF | N/A | Benchmarking of automated cancer cell annotation methods for scRNA-seq data reveals Consensus annotation as the preferred method | | 靶向贫血诱导的CD71+网织红细胞可保护小鼠免受疟原虫感染 | Zeydabadinejad, S. | PDF | N/A | Targeting anemia-induced CD71+ reticulocytes protects mice from Plasmodium infection | | 以下是这段英文的中文翻译:

物种依赖性代谢的共价nsP2蛋白酶抑制剂及其体内抗甲病毒活性

翻译解释: - Species Dependent Metabolism:物种依赖性代谢,指的是不同物种对同一化合物的代谢方式可能不同。 - Covalent nsP2 Protease Inhibitor:共价nsP2蛋白酶抑制剂,nsP2是一种病毒蛋白酶,这种抑制剂通过共价键与之结合。 - in Vivo Anti-alphaviral Activity:体内抗甲病毒活性,指的是该化合物在活体实验中对甲病毒(Alphavirus)具有抑制或杀灭作用。

希望这对你有帮助! | Hossain, M. A. | PDF | N/A | Species Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with in Vivo Anti-alphaviral Activity | | 膳食蛋白质对细胞衰老的组织特异性效应是由支链氨基酸介导的。 | Calubag, M. F. | PDF | N/A | Tissue-specific effects of dietary protein on cellular senescence are mediated by branched-chain amino acids | | 对后口动物支系的支持来自于系统误差。 | Silva, A. S. | PDF | N/A | Support for the deuterostome clade comes from systematic errors | | 科罗拉多马铃薯甲虫(Leptinotarsa decemlineata)的cys-loop配体门控离子通道基因超家族 | Chen, D. | PDF | N/A | The cys-loop ligand-gated ion channel gene superfamily of the Colorado potato beetle, Leptinotarsa decemlineata | | 《果蝇嗅觉系统的解剖、功能与进化的综合视角》 | Benton, R. | PDF | N/A | An integrated anatomical, functional and evolutionary view of the Drosophila olfactory system | | NimA在果蝇神经系统的血脑屏障中促进细胞粘附。 | Sakr, R. | PDF | N/A | NimA promotes cell adhesion at the blood brain barrier of Drosophila nervous system | | 细胞周期依赖的信号调控果蝇中枢大脑神经干细胞的时间模式形成 | Syed, M. H. | PDF | N/A | Cell-cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells | | 多层调控是嗅觉系统功能精确性和进化能力的基础。 | Mermet, J. | PDF | N/A | Multilayer regulation underlies the functional precision and evolvability of the olfactory system | | 三种物种,三个实验室,三项实验:在多实验室环境下测试昆虫行为生态学研究的可重复性。 | Mundinger, C. | PDF | N/A | Three species, three labs, three experiments: testing the reproducibility of ecological studies on insect behaviour in a multi-laboratory setting | | 社会缓冲作为一种间接效应:混合效应建模方法 | Sekhar, M. A. | PDF | N/A | Social buffering as an indirect effect: mixed-effects modeling approaches | | 在临床相关场强下重复进行经颅直流电刺激(tDCS)可以促进大鼠的同时运动学习。 | Farahani, F. | PDF | N/A | Repeated tDCS at clinically-relevant field intensity can boost concurrent motor learning in rats. | | 蚂蚁视觉路径导航:行为细节如何促进成功的路径表现和趋同 | Azevedo Amin, A. | PDF | N/A | Ant visual route navigation: How the fine details of behaviour promote successful route performance and convergence | | 冗余且弱连接的前额叶半球在空间工作记忆中的精确性和容量之间保持平衡。 | Tschiersch, M. | PDF | N/A | Redundant, weakly connected prefrontal hemispheres balance precision and capacity in spatial working memory | | 环境、发育和遗传条件对帝王蝶迁徙行为的影响 | Tsai, H.-Y. | PDF | N/A | Environmental, Developmental, and Genetic Conditions Shaping Monarch Butterfly Migration Behavior | | 在视觉和空间工作记忆范式的早期测试阶段,清洁鱼未能通过测试。 | Bonin, L. | PDF | N/A | Cleaner wrasse failed in early testing stages of both visual and spatial Working Memory paradigms | | 《Cuevas de la Arana(西班牙比科尔普)岩画遗址的心理声学研究》 | Lopez, S. | PDF | N/A | Psychoacoustic Study of the Rock Art Sites of Cuevas de la Arana (Bicorp, Spain) | | 使用气溶素纳米孔对未标记的全长蛋白质进行基于电荷的指纹识别 | Rukes, V. | PDF | N/A | Charge-based fingerprinting of unlabeled full-length proteins using an aerolysin nanopore | | SwarmMAP:用于单细胞测序数据中分散细胞类型注释的群体学习 | Goepp, V. | PDF | N/A | SwarmMAP: Swarm Learning for Decentralized Cell Type Annotation in Single Cell Sequencing Data | | 3D多光子纳米光刻技术与生物可降解氨基酸基树脂 | Naderer, C. | PDF | N/A | 3D Multiphoton Nanolithography with Bioresorbable Amino Acid-Based Resins | | 错配修复缺陷型肺腺癌模型中的位点特异性免疫原性和抗PD1反应 | Abad, E. | PDF | N/A | Site-specific immunogenicity and anti-PD1 response in mismatch repair deficient lung adenocarcinoma models | | 肠道干细胞标记物MEX3A调控PPARγ表达,对结直肠癌发生具有功能性影响 | Silva, A. R. | PDF | N/A | Intestinal stem cell marker MEX3A regulates PPARγ expression with functional impact in colorectal carcinogenesis | | 依赖经验的重组抑制性神经元突触连接 | Fink, A. J. P. | PDF | N/A | Experience-dependent reorganization of inhibitory neuron synaptic connectivity | | 连续的视觉刺激会增加视觉皮层中的高频功率。 | Keil, J. | PDF | N/A | Sequential visual stimuli increase high frequency power in the visual cortex | | 内皮细胞依赖tPA招募小胶质细胞至血管周围在小鼠中风后保护血脑屏障 | Etuze, T. | PDF | N/A | Endothelial tPA-dependent recruitment of microglia to vessels protects the blood-brain barrier after stroke in mice | | 等长握力收缩以剂量依赖性方式增加胫骨前肌内在运动神经元的兴奋性。 | Ugliara, L. | PDF | N/A | Isometric handgrip contraction increases tibialis anterior intrinsic motoneuron excitability in a dose-dependent manner | | 猕猴眼跳运动前的颅脑准备电位 | Errington, S. P. | PDF | N/A | A preparatory cranial potential for saccadic eye movements in macaque monkeys | | 由功能性磁共振成像揭示的人类大脑全脑活动的定量时空关系 | Huang, J. | PDF | N/A | The quantitative spatiotemporal relationship of whole brain activity of human brains revealed by fMRI | | 人类和啮齿动物的癫痫发作显示出与扩散性去极化的动态相互作用 | Norby, J. H. | PDF | N/A | Human and Rodent Seizures Demonstrate a Dynamic Interplay with Spreading Depolarizations | | 以下是这段英文的中文翻译:

Sarm1基因缺失成年小鼠体内单根激光切断角膜神经纤维的形态动力学研究

翻译说明: - "In vivo" 翻译为 "体内" - "Morphological Dynamics" 翻译为 "形态动力学" - "Single Laser-Axotomized" 翻译为 "单根激光切断" - "Corneal Nerve Fibers" 翻译为 "角膜神经纤维" - "Sarm1-Null" 翻译为 "Sarm1基因缺失" - "Adult Mice" 翻译为 "成年小鼠"

希望这个翻译对你有帮助! | Inigo-Portugues, A. | PDF | N/A | In vivo Morphological Dynamics of Single Laser-Axotomized Corneal Nerve Fibers in Sarm1-Null Adult Mice | | 以下是这段英文的中文翻译:

致幻剂暴露后前额叶皮层神经元类型中替代剪接的持续性大规模变化

翻译解释: - Persistent:持续性的 - large-scale changes:大规模变化 - alternative splicing:替代剪接(一种基因表达调控机制) - prefrontal cortical neuron types:前额叶皮层神经元类型 - psychedelic exposure:致幻剂暴露

整句话的意思是:在暴露于致幻剂后,前额叶皮层神经元类型中的替代剪接机制发生了持续性的大规模变化。 | Hsiao, Y. | PDF | N/A | Persistent large-scale changes in alternative splicing in prefrontal cortical neuron types following psychedelic exposure | | Plectin调节小鼠星形胶质细胞中的粘着斑动力学和细胞骨架组织:对反应性星形胶质细胞增生的影响

在这段翻译中,"Plectin"是一种蛋白质的名称,通常不翻译,保留原文。"Regulates"翻译为“调节”,表示控制或管理。"Focal Adhesion Dynamics"翻译为“粘着斑动力学”,指的是细胞与细胞外基质之间的动态相互作用。"Cytoskeletal Organization"翻译为“细胞骨架组织”,涉及细胞内部结构的排列和组织。"Mouse Astrocytes"翻译为“小鼠星形胶质细胞”,指的是小鼠大脑中的一种支持性细胞。"Implications for Reactive Astrogliosis"翻译为“对反应性星形胶质细胞增生的影响”,指的是研究结果对理解星形胶质细胞在损伤或疾病中的反应性变化的意义。 | Furlani, B. | PDF | N/A | Plectin Regulates Focal Adhesion Dynamics and Cytoskeletal Organization in Mouse Astrocytes: Implications for Reactive Astrogliosis | | VeCell:一个Fiji插件,用于揭示大胶质细胞发育及其与血管接近性的时空动态 | Guille, N. | PDF | N/A | VeCell: A Fiji Plugin to unveil the spatio-temporal dynamics of macroglial cell development and proximity to blood vessels | | 视觉搜索中的不确定性:来自自然刺激下计算模型与行为实验的洞见 | Bujia, G. | PDF | N/A | Uncertainty during visual search: Insights from a computational model and behavioral experiment in natural stimuli | | 年龄在战略控制回忆内容中的影响,通过场景重建的调节反映出来。 | de Chastelaine, M. | PDF | N/A | Effects of age in the strategic control of recollected content as reflected by modulation of scene reinstatement | | 内侧内嗅皮层-海马去同步化与阿尔茨海默病病理小鼠模型中记忆障碍的出现相平行 | Vetere, L. M. | PDF | N/A | Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology | | 在概率线索下,反向阿尔法振荡塑造感知偏差 | Tarasi, L. | PDF | N/A | Backward alpha oscillations shape perceptual bias under probabilistic cues | | 验证结构张量分析在脑组织显微镜中用于方向估计的有效性 | Gray, B. | PDF | N/A | Validation of Structure Tensor Analysis for Orientation Estimation in Brain Tissue Microscopy | | 钙调磷酸酶介导的GAP-43调控对于神经突触和突触的形成至关重要,并且能够防止α-突触核蛋白诱导的神经退行性变。 | Zaichick, S. | PDF | N/A | Calcineurin-mediated regulation of GAP-43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration | | 个性化α频段经颅交流电刺激对疼痛感知和神经振荡的调节作用:一项针对健康参与者的假刺激对照研究 | Fathi, Y. | PDF | N/A | Individualized Alpha-tACS for Modulating Pain Perception and Neural Oscillations: A Sham-Controlled Study in Healthy Participants | | 丘脑参与定义了非快速眼动(NREM)睡眠中不同的慢波亚型。 | Bergamo, D. | PDF | N/A | Thalamic involvement defines distinct slow-wave subtypes in NREM sleep | | P4B-2412作为磷酸二酯酶4B放射性配体用于正电子发射断层扫描成像的临床前评估 | Song, Z. | PDF | N/A | Preclinical Evaluation of P4B-2412 as Phosphodiesterase 4B Radioligand for Positron Emission Tomography Imaging | | 优化SARS-CoV-2 RBD边界以增强大肠杆菌表达 | Biswas, A. | PDF | N/A | Optimizing SARS-CoV-2 RBD Boundaries for Enhanced E. coli Expression | | 技术和生物来源的噪声干扰了多重增强子AAV筛选。 | Hunker, A. C. | PDF | N/A | Technical and biological sources of noise confound multiplexed enhancer AAV screening | | 脂磷壁酸在金黄色葡萄球菌细胞壁完整性中的作用 | Bae, T. | PDF | N/A | The role of lipoteichoic acid in Staphylococcus aureus cell wall integrity | | 对人类肠道细菌中胆汁盐水解酶活性的研究揭示了共轭次级胆汁酸的产生 | Lucas, L. N. | PDF | N/A | Investigation of Bile Salt Hydrolase Activity in Human Gut Bacteria Reveals Production of Conjugated Secondary Bile Acids | | 一种适应于缺氧冷泉沉积物的无板纲软体动物中用于化学共生的多层膜细胞器 | Li, Y. | PDF | N/A | A multilamellar organelle for chemosymbiosis in an aplacophoran mollusc adapted to anoxic cold seep sediment | | 根际定殖细菌在原生生物微生物组中持续存在 | Taerum, S. J. | PDF | N/A | Rhizosphere-colonizing bacteria persist in the protist microbiome | | 环境因素驱动胃肠道黏液的细菌降解 | Arias, S. L. | PDF | N/A | Environmental factors drive bacterial degradation of gastrointestinal mucus | | 末端补体复合物(无论是否含有C9)增强了针对淋病奈瑟菌的抗菌活性。 | Lamb, E. R. | PDF | N/A | Terminal complement complexes with or without C9 potentiate antimicrobial activity against Neisseria gonorrhoeae | | 通过对保守RNA结构进行计算机筛选,鉴定出巴西利什曼原虫中一种新型长链非编码RNA的功能特性研究

这段翻译将原标题“Functional Characterization of a Novel Long Non-Coding RNA in Leishmania braziliensis Identified Through Computational Screening for Conserved RNA Structures”转化为中文,同时保持了原文的科学性和准确性。翻译中,“Functional Characterization”译为“功能特性研究”,“Novel Long Non-Coding RNA”译为“新型长链非编码RNA”,“Leishmania braziliensis”保留为“巴西利什曼原虫”,“Identified Through Computational Screening for Conserved RNA Structures”则译为“通过对保守RNA结构进行计算机筛选鉴定出”。整体翻译流畅,符合中文表达习惯,同时准确传达了原文的科学信息。 | Espada, C. R. | PDF | N/A | Functional Characterization of a Novel Long Non-Coding RNA in Leishmania braziliensis Identified Through Computational Screening for Conserved RNA Structures | | 创建和验证用于蛋白质检测和分析的全蛋白质组酵母文库 | Baruch, D. | PDF | N/A | Creation and Validation of a Proteome-Wide Yeast Library for Protein Detection and Analysis | | 城市作物展现出与自然生态系统相当的有机碳储存潜力。 | Prieto, B. J. | PDF | N/A | Urban crops demonstrate comparable potential for organic carbon storage as natural ecosystems. | | RPA磷酸化编码的启动和调节机制通过Cdk1/Wee1信号回路实现 | Roshan, P. | PDF | N/A | Mechanism of RPA phosphocode priming and tuning by Cdk1/Wee1 signaling circuit | | 错配修复因子Mlh1-Pms1利用ATP来压缩和重塑DNA。 | Collingwood, B. W. | PDF | N/A | The mismatch repair factor Mlh1-Pms1 uses ATP to compact and remodel DNA | | 一种针对疟疾病原体恶性疟原虫溴结构域PfBDP1的新型抑制剂 | Amann, M. | PDF | N/A | A novel inhibitor against the bromodomain PfBDP1 of the malaria pathogen Plasmodium falciparum | | 致癌的CCDC6-RET融合产物是一种依赖ATP和ADP的双重激酶,通过顺式磷酸化发挥作用。 | Martin-Hurtado, A. | PDF | N/A | The oncogenic CCDC6-RET fusion product is a dual ATP and ADP-dependent kinase that functions via cis-phosphorylation | | 在刚果民主共和国与安哥拉边境地区,发现了登革热病毒传播的证据以及多样化的伊蚊病毒组。 | He, W. | PDF | N/A | Evidence of dengue virus transmission and a diverse Aedes mosquito virome on the Democratic Republic of Congo-Angola border | | 使用多层链图分析猪源弯曲杆菌中氟喹诺酮类和大环内酯类耐药性的风险因素 | Wang, C. A. | PDF | N/A | Risk factors for fluoroquinolone- and macrolide-resistance among swine Campylobacter coli using multi-layered chain graphs | | 噬菌体防御系统的丰度在不同环境中有所变化,并随着病毒密度的增加而增加。 | Meaden, S. | PDF | N/A | Phage defence system abundances vary across environments and increase with viral density | | 在抗生素时代之后,历史临床分离株中的基因组耐药性在频率和移动性上都有所增加。 | Kaul, A. | PDF | N/A | Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics | | 这段文字的中文翻译是:

“黑曲霉转录因子MsnA与VelB之间的分子回路协调真菌应激与发育反应”

解释: - Molecular circuit:分子回路,指的是生物体内分子之间的相互作用和调控网络。 - Aspergillus nidulans:黑曲霉,一种常见的模式真菌,常用于科学研究。 - Transcription factors:转录因子,调控基因表达的蛋白质。 - MsnA and VelB:两种特定的转录因子名称。 - Coordinate:协调,指调控或整合不同的生物过程。 - Fungal stress and developmental responses:真菌的应激反应和发育反应,分别指真菌在应对环境压力(如氧化、温度变化等)和生长发育过程中的调控机制。

整体意思是,研究揭示了黑曲霉中MsnA和VelB两种转录因子之间的分子调控机制,这些机制共同协调真菌在应对环境压力和生长发育过程中的反应。 | Bastakis, E. | PDF | N/A | Molecular circuit between Aspergillus nidulans transcription factors MsnA and VelB to coordinate fungal stress and developmental responses | | 反应性星形胶质细胞的翻译景观揭示了eIF2B介导的调控失调在VWM疾病中的影响 | Mandelboum, S. | PDF | N/A | The Translational Landscape of Reactive Astrocytes Reveals the Impact of eIF2B-mediated Dysregulation in VWM Disease | | 开发针对不良心脏重构的条件性siRNA可编程核糖开关 | Gokulnath, P. | PDF | N/A | Development of conditional-siRNA programmable riboswitch for targeting adverse cardiac remodeling | | 不成熟小鼠视网膜细胞中,由短DNA连接子间隔不规则的核小体驱动的2-起始锯齿形染色质折叠受损。 | Kable, B. | PDF | N/A | Compromised 2-start zigzag chromatin folding in immature mouse retina cells driven by irregularly spaced nucleosomes with short DNA linkers. | | 重组克隆的一个实验现象挑战了关于质粒共转化、选择和维持的传统观念。 | Geer, C. L. | PDF | N/A | An artifact of recombinatorial cloning challenges established beliefs of plasmid co-transformation, selection, and maintenance | | Rad5与端粒复制 | Mattarocci, S. | PDF | N/A | Rad5 and Telomere Replication | | 空间捕获-再捕获研究揭示了波罗的海鲑鱼拖网渔业中的资源利用情况以及船长的数量下降。 | Karlsson, K. | PDF | N/A | Spatial capture-recapture reveals resource use and declining skipper numbers in Baltic Sea salmon trolling fisheries | | 培育赋予植物耐盐性的微生物群落 | Pereira, C. G. | PDF | N/A | Breeding of microbiomes conferring salt tolerance to plants | | 着丝粒通过选择在动粒界面处逐步进化。 | Helsen, J. | PDF | N/A | Centromeres evolve progressively through selection at the kinetochore interface | | ntSynt-viz:可视化跨多个基因组的共线性模式 | Coombe, L. | PDF | N/A | ntSynt-viz: Visualizing synteny patterns across multiple genomes | | 优化小鼠元转录组分析,通过选择性去除冗余核酸序列 | Kuersten, S. | PDF | N/A | Optimizing mouse metatranscriptome profiling by selective removal of redundant nucleic acid sequences | | 原位光驱动pH调节用于核磁共振研究 | Barde, A. | PDF | N/A | In situ light-driven pH modulation for NMR studies | | 巴雷特食管和食管腺癌中微生物进化的群落组装模型 | Guccione, C. | PDF | N/A | Community assembly modeling of microbial evolution within Barrett's esophagus and esophageal adenocarcinoma | | 类别偏向性补丁环绕在人类外侧前额叶皮层的核心通用领域区域周围。 | Assem, M. | PDF | N/A | Category-biased patches encircle core domain-general regions in the human lateral prefrontal cortex | | 内侧前额叶皮层将程序性规则编码为连续的神经元活动动态。 | Ohno, S. | PDF | N/A | The medial prefrontal cortex encodes procedural rules as sequential neuronal activity dynamics | | 小胶质细胞调控伏隔核突触发育和威胁回避行为的神经回路功能 | Gongwer, M. W. | PDF | N/A | Microglia regulate nucleus accumbens synaptic development and circuit function underlying threat avoidance behaviors | | 开发一种利用网状过滤器分离秀丽隐杆线虫胚胎的尺寸分离技术 | Jhaveri, N. S. | PDF | N/A | Development of a size separation technique to isolate Caenorhabditis elegans embryos using mesh filters | | 杂交何时会带来长期效益? | Schneemann, H. | PDF | N/A | When will hybridization bring long-term benefits? | | 在发育和细胞谱系选择的背景下,突变率的演变 | Majic, P. | PDF | N/A | The evolution of mutation rates in the light of development and cell-lineage selection | | 瓶颈期间功能基因组多样性的演变 | Schlichta, F. | PDF | N/A | Evolution of functional genomic diversity during a bottleneck | | 重复刺激会改变神经类器官回路的网络特性。 | Chow, S. Y. A. | PDF | N/A | Repetitive stimulation modifies network characteristics of neural organoid circuits |