BioRxiv 2025-01-19 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 实验室小鼠的视频表型分析平台 | Choudhary, A. | N/A | Video based phenotyping platform for the laboratory mouse | |
| 线粒体自噬受体BNIP3L/Nix协调核钙信号以调节肌肉表型。 | Field, J. T. | N/A | The mitophagy receptor BNIP3L/Nix coordinates nuclear calcium signaling to modulate the muscle phenotype. | |
| 增强型双重稳健后插补推断在蛋白质组学数据中的应用 | Moon, H. | N/A | Augmented Doubly Robust Post-Imputation Inference for Proteomic data | |
| 冷冻电镜引导的查加斯病疫苗候选物TcPOP开放和封闭构象的分析及其抗体反应特征研究 | Batra, S. | N/A | Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation | |
| 传粉者对当地和景观草地特征的响应存在差异 | Lichtenberg, E. M. | N/A | Pollinators differentially respond to local and landscape grassland features | |
| 海百合基于视蛋白的光感受：对Antedon bifida的分子与行为研究 | Nonclercq, Y. | N/A | Opsin-based photoreception in Crinoids: a molecular and behavioural study of Antedon bifida | |
| 自组织的噬菌体与宿主菌落群体的共存 | Yadav, A. | N/A | Self-organized coexistence of phage and a population of host colonies | |
| MLPA：一种用于个性化癌症模拟与治疗优化的多尺度数字孪生框架 | Chen, J. Y. | N/A | MLPA: A Multi-scale Digital Twin Framework for Personalized Cancer Simulation and Treatment Optimization | |
| 使用镜像正向遗传学方法鉴定作用于核非编码RNA的人类通路 | Che, R. | N/A | Identification of Human Pathways Acting on Nuclear Non-Coding RNAs Using the Mirror Forward Genetic Approach | |
| 传统经颅直流电刺激（tDCS）与高清晰度经颅直流电刺激（HD-tDCS）对小脑的偏移镇痛效果差异 | O'Connor, N. | N/A | Differential effects of conventional transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) of the cerebellum on offset analgesia | |
| 实时预测和相位靶向脑振荡 | Jongejan, S. L. | N/A | Predicting and phase targeting brain oscillations in real-time | |
| 前扣带皮层中用于信息和努力选择的常见持续目标机制 | Gonzalez, V. V. | N/A | A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices | |
| 优势逆转在时间变化的环境中维持了大效应抗性多态性。 | Karageorgi, M. | N/A | Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments | |
| 解码肝癌预后：从多组学亚型、预后模型到单细胞验证 | Wang, Y. | N/A | Decoding Liver Cancer Prognosis: From Multi-omics Subtypes, Prognostic Models to Single Cell Validation | |
| 大脑特征图揭示了腹侧流中逐步发展的动物特征表征。 | Zhang, Z. | N/A | Brain Feature Maps Reveal Progressive Animal-Feature Representations in the Ventral Stream. | |
| 蚂蚁根据过去、即将发生和预测的逆境进行适应性决策 | Notomi, Y. | N/A | Adaptive decision-making by ants in response to past, imminent, and predicted adversity | |
| DNA甲基化影响大肠杆菌中的基因表达，但不影响其全局染色质结构。 | Morgan, W. J. | N/A | DNA methylation affects gene expression but not global chromatin structure in Escherichia coli | |
| 通过冷冻电镜和分子动力学模拟揭示的血管紧张素-I转换酶的二聚化和动力学 | mancl, j. M. | N/A | Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations | |
| 由微外显子跳跃定义的神经元细胞粘附分子（NRCAM）变体是高级别胶质瘤中一种重要的、抗原性独特的且可靶向的蛋白质形式。 | Sehgal, P. | N/A | Neuronal cell adhesion molecule (NRCAM) variant defined by microexon skipping is an essential, antigenically distinct, and targetable proteoform in high-grade glioma | |
| SFCalculator：连接深度生成模型与晶体学 | Li, M. | N/A | SFCalculator: connecting deep generative models and crystallography | |
| 拥挤效应和序列依赖在视觉感知中的相互影响 | Cass, J. | N/A | Reciprocal roles of crowding and serial dependence on visual perception | |
| UFMylation与核糖体相关质量控制途径的协同作用清除了内质网上停滞的新生链。 | Mihailovic, M. | N/A | The coordinated action of UFMylation and ribosome-associated quality control pathway clears arrested nascent chains at the endoplasmic reticulum | |
| 在一项关于滤食性两栖动物的研究中发现，微塑料暴露对其生长产生了负面影响，但并未显著影响皮质酮水平、氧化应激或端粒长度。 | Martin, C. A. | N/A | Growth but not corticosterone, oxidative stress or telomere length is negatively affected by microplastic exposure in a filter-feeding amphibian | |
| 霉菌毒素白僵菌素是组织蛋白酶B的非竞争性抑制剂。 | Yang, X. | N/A | The mycotoxin Beauvericin is an uncompetitive inhibitor of Cathepsin B | |
| B4GALNT1在神经节苷脂合成中的构象动力学与膜插入机制 | Welland, J. W. J. | N/A | Conformational Dynamics and Membrane Insertion Mechanism of B4GALNT1 in Ganglioside Synthesis | |
| 荧光寿命成像显微镜用于三阴性乳腺癌中LDHB抑制的代谢分析 | Galloway, A. E. | N/A | Fluorescence lifetime imaging microscopy for metabolic analysis of LDHB inhibition in triple negative breast cancer | |
| 诱导极化在药物发现应用中的作用 | Mohamed, A. | N/A | The role of induced polarization in drug discovery applications | |
| 使用对比学习和领域对抗学习对细胞涂片数据进行三重效应校正 | Yan, C. | N/A | Triple-effect correction for Cell Painting data with contrastive and domain-adversarial learning | |
| 轴突中ATP运输的建模：自发性神经元放电和通过隧道纳米管的线粒体转移的影响 | Kuznetsov, A. V. | N/A | Modeling of ATP Transport in an Axon: Effects of Spontaneous Neuron Firing and Mitochondrial Transfer via Tunneling Nanotubes | |
| 胰腺导管腺癌基质亚型与神经侵袭关系的转录组学分析 | Yildizhan, S. E. | N/A | Transcriptomic Analysis Of The Relationship Between Pancreatic Ductal Adenocarcinoma Stromal Subtypes And Neural Invasion | |
| 女性自发性高血压大鼠冠状动脉微血管功能障碍（CMD）的动物模型：饮食的作用 | Najjar, R. S. | N/A | An animal model of coronary microvascular dysfunction (CMD) in the female spontaneously hypertensive rat: the role of diet | |
| 造血衰老的三个表型特征的独特原因 | Chia, J. J. | N/A | Distinct causes of three phenotypic hallmarks of hematopoietic aging | |
| 通过CRISPR-Cas9技术敲除干扰素受体，研究大西洋鲑鱼细胞中的抗病毒通路。 | Reza, M. A. N. | N/A | Investigating antiviral pathways in Atlantic salmon cells through interferon receptor knockouts via CRISPR-Cas9 | |
| 用于研究核小体重定位的天然核小体定位元件 | Chen, R.-W. | N/A | Native nucleosome-positioning elements for the investigation of nucleosome repositioning | |
| KIDINS220和InsP8确保了磷酸盐输出蛋白XPR1的逐步调控。 | Wang, X. | N/A | KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1 | |
| 解密微小隐孢子虫中的转录过程：多顺反子基因表达与染色质可及性 | Xiao, R. | N/A | Deciphering Transcription in Cryptosporidium parvum: Polycistronic Gene Expression and Chromatin Accessibility | |
| 关于胰腺细胞中CFTR基因顺式调控的新见解 | Blotas, C. | N/A | New insights into the cis-regulation of the CFTR gene in pancreatic cells | |
| 热循环转录提高了RNA的产量。 | Liu, Y. | N/A | Thermal cycling transcription boosts RNA production. | |
| VitisC：通过细胞骨架集成支架可视化感兴趣的目标 | Yin, B. | N/A | VitisC: Visualizing interested target via integrated scaffold of cytoophidium | |
| 脂质锥超家族：脂质、肽聚糖和胞外多糖代谢、生物间冲突与免疫的统一主题 | Burroughs, A. M. | N/A | The Lipocone Superfamily: A Unifying Theme In Metabolism Of Lipids, Peptidoglycan And Exopolysaccharides, Inter-Organismal Conflicts And Immunity | |
| BK通道的内在开放源于疏水门控中的固有泄漏 | Jia, Z. | N/A | Intrinsic Opening of BK Channels Derives from Inherent Leakage in Hydrophobic Gating | |
| 微滴中的数字噬菌体生物学 | Givelet, L. | N/A | Digital Phage Biology in Droplets | |
| 启用xMAS构建器对复杂弯曲细胞膜进行原子级建模与仿真 | Trebesch, N. | N/A | Enabling Atomistic Modeling and Simulation of Complex Curved Cellular Membranes with xMAS Builder | |
| HPV阴性头颈鳞状细胞癌（HPV- HNSCC）中外周和肿瘤浸润免疫细胞的单细胞景观 | Galvani, R. G. A. | N/A | The Single-Cell Landscape of Peripheral and Tumor-infiltrating Immune Cells in HPV- HNSCC | |
| 导管内乳头状黏液性肿瘤的细胞可塑性与重复元件失调相关 | Pankaj, A. | N/A | Intraductal Papillary Mucinous Neoplasm Cellular Plasticity linked with Repeat Element Dysregulation | |
| H3K27me3和PRC1-H2AK119ub通路在H3K9甲基化缺失后协同维持异染色质和转录沉默。 | Fukuda, K. | N/A | H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation | |
| 周期性障碍调节膜张力传播以实现局部机械转导 | Catala, F. | N/A | Periodic Obstacles Regulate Membrane Tension Propagation to Enable Localized Mechanotransduction | |
| 一种新颖的优化硝酸银染色方法用于可视化骨细胞陷窝-小管系统 | Wu, J. | N/A | A Novel Optimized Silver Nitrate Staining Method for Visualizing the Osteocyte Lacuno-Canalicular System | |
| 在系统性硬化症中绘制空间分辨转录组图谱 | Li, Z. | N/A | Mapping spatially-resolved transcriptomes in systemic sclerosis | |
| 以下是这段英文的中文翻译： |
黄曲霉（Aspergillus flavus）着丝粒和亚端粒染色体区域中串联反向重复序列的聚类
翻译说明： - Clustering 翻译为“聚类”，表示某种模式或结构的集中分布。 - Tandem Inverse Duplications 翻译为“串联反向重复序列”，指的是基因组中重复出现的序列，且方向相反。 - Centromeric and Subtelomeric Chromosomal Regions 翻译为“着丝粒和亚端粒染色体区域”，分别指染色体中靠近着丝粒和端粒的区域。 - Aspergillus flavus 是“黄曲霉”的学名，是一种常见的真菌。
希望这段翻译对你有帮助！ | Lustig, A. J. | PDF | N/A | Clustering of Tandem Inverse Duplications in Centromeric and Subtelomeric Chromosomal Regions of Aspergillus flavus | | 以下是将这段英文翻译成中文的结果：
一种用于多重诊断中高效分离血浆的纸-液滴混合系统
这个翻译保留了原文的技术性和专业性，同时使用了中文中常见的表达方式。"Paper-Droplet Hybrid System" 翻译为 "纸-液滴混合系统"，"Efficient Blood Plasma Separation" 翻译为 "高效分离血浆"，"Multiplex Diagnostics" 翻译为 "多重诊断"。整个翻译简洁明了，准确传达了原文的含义。 | Dash, A. | PDF | N/A | A Paper-Droplet Hybrid System for Efficient Blood Plasma Separation in Multiplex Diagnostics | | 基础架构支持国际空间站与地球之间进行联合学习，用于训练空间生物医学机器学习模型 | Casaletto, J. A. | PDF | N/A | Foundational Architecture Enabling Federated Learning for Training Space Biomedical Machine Learning Models between the International Space Station and Earth | | 转录组特征揭示结肠癌对微管抑制剂的敏感性 | Linares-Blanco, J. | PDF | N/A | Transcriptomic signature reveals sensitivity to tubulin inhibitors in colon cancer | | 人类胰腺中原生导管细胞群的空间分布图及其在胰腺癌中的表现 | Van den Bossche, J.-L. | PDF | N/A | Spatial map of native duct cell populations in human pancreas and their representation in pancreatic cancers | | 高通量骨髓3D共培养系统用于开发B细胞非霍奇金淋巴瘤中针对B细胞受体信号通路靶向药物的耐药性 | Zadro, A. | PDF | N/A | A High-Throughput Bone Marrow 3D Co-Culture System to Develop Resistance to B Cell Receptor Signaling Targeted Agents in B Cell Non-Hodgkin Lymphoma | | 合成和植物来源的多价半乳聚糖作为癌症相关半乳糖凝集素-3和-9的调节剂 | Pfeifer, L. | PDF | N/A | Synthetic and plant-derived multivalent galactans as modulators of cancer-associated galectins-3 and -9 | | 基于序列的药物-靶点复合物预训练增强了蛋白质-配体结合过程的预测，应对隐秘性问题 | Zhang, S. | PDF | N/A | Sequence-based Drug-Target Complex Pre-training Enhances Protein-Ligand Binding Process Predictions Tackling Crypticity | | 功能多样化的BiP同源物在秀丽隐杆线虫中调控身体生长、繁殖、抗逆性、衰老以及内质网自噬。 | Urban, N. D. | PDF | N/A | Functionally diversified BiP orthologs control body growth, reproduction, stress resistance, aging, and ER-Phagy in Caenorhabditis elegans. | | 改变的松弛和线粒体-内质网接触位点先于衰老骨骼肌中的主要（不良）适应，并通过运动得以预防 | Allen, R. J. | PDF | N/A | Altered Relaxation and Mitochondria-Endoplasmic Reticulum Contact Sites Precede Major (Mal)adaptations in Aging Skeletal Muscle and are Prevented by Exercise | | 对经尸检确诊的进行性核上性麻痹患者的HLA基因座进行研究 | Wang, J. | PDF | N/A | Investigation of the HLA locus in autopsy-confirmed progressive supranuclear palsy | | 火改变了地中海沿海沙丘生态系统中木本植物群落的结构和动态。 | Mira, A. F. | PDF | N/A | Fire shifts the structure and dynamics of woody plant communities in a mediterranean coastal dune ecosystem | | 在废水管理的背景下，环境因素对人工湿地微生物多样性和功能的影响 | Grandmond-Lemire, S. | PDF | N/A | Environmental effects on constructed wetland microbial diversity and function in the context of wastewater management | | 利用人工智能探索药物结合中翻译后修饰的结构背景 | Medvedev, K. E. | PDF | N/A | Leveraging AI to Explore Structural Contexts of Post-Translational Modifications in Drug Binding | | 接触模式高速原子力显微镜（AFM）用于研究相分离脂质双层与淀粉样蛋白-β（amyloid-β）的相互作用 | Robinson, M. | PDF | N/A | Contact mode high-speed AFM of phase separated lipid bilayers to study amyloid-β interactions | | 利用细胞FAD自发荧光作为无标记细胞属性用于生产嵌合抗原受体-T细胞 | Cheung, K.-W. | PDF | N/A | Use of cellular FAD autofluorescence as a label-free cellular attribute for the production of chimeric antigen receptor-T cells | | IL-9作为一种天然正交细胞因子，具有最佳的JAK/STAT信号通路，适用于工程化T细胞治疗。 | Jiang, H. | PDF | N/A | IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy | | 真社会性在单倍二倍体昆虫中以更高的速率进化。 | Suresh, S. | PDF | N/A | Eusociality evolved at a much higher rate in haplodiploid insects | | 酵母蛋白Rnq1形成的朊病毒类型和液态样聚集体的形成，受其非朊病毒结构域和朊病毒结构域之间相互作用的调控。 | Derkatch, I. L. | PDF | N/A | The types of prions and liquid-like aggregates formed by the yeast protein Rnq1 are controlled by interactions between its non-prion and prion domains | | 比较森林景观中黄尾熊蜂与蜜蜂的季节性饮食：基于元条形码技术的研究
这段翻译将英文标题“Comparing the Seasonal Diets of Buff-tailed Bumblebees and Honey Bees in a Forest Landscape: A Metabarcoding Approach”转化为中文，同时保持了原文的学术性和专业性。翻译中，“Buff-tailed Bumblebees”译为“黄尾熊蜂”，“Honey Bees”译为“蜜蜂”，“Forest Landscape”译为“森林景观”，“Seasonal Diets”译为“季节性饮食”，而“Metabarcoding Approach”则译为“元条形码技术”，这些都是生物学和生态学领域常用的术语。整个标题的翻译旨在准确传达原文的研究内容和采用的方法。 | Gay, C. | PDF | N/A | Comparing the Seasonal Diets of Buff-tailed Bumblebees and Honey Bees in a Forest Landscape: A Metabarcoding Approach | | 鼹鼠蟋蟀的多种运动步态 | Yuval, O. | PDF | N/A | Multiple locomotion gaits in the mole cricket | | DiffHiChIP：从HiChIP数据中识别差异染色质接触 | Bhattacharyya, S. | PDF | N/A | DiffHiChIP: Identifying differential chromatin contacts from HiChIP data | | MetaLigand：一个用于预测非肽配体介导的细胞间通讯的数据库 | Xin, Y. | PDF | N/A | MetaLigand: A database for predicting non-peptide ligand mediated cell-cell communication | | 右前额叶下皮层在共情物理疼痛和社会疼痛中的因果性和可分离性作用 | De Lillo, M. | PDF | N/A | A Causal and Dissociable Role for the Right Inferior Prefrontal Cortex in Empathy for Physical and Social Pain | | 社交视觉的共享与个体调谐曲线 | Varrier, R. S. | PDF | N/A | Shared and individual tuning curves for social vision | | NMDA谷氨酸受体介导的海马可塑性与记忆的转录和突触调控 | Parra-Damas, A. | PDF | N/A | Transcriptional and synaptic regulation of NMDA glutamate receptor-mediated hippocampal plasticity and memory | | 阐述大鼠闭环前脑回路的连接：在皮质-纹状体-苍白球三重下行投射中，与丘脑反馈至前外侧下丘脑区域的新地形学证据的限定性研究。 | Negishi, K. | PDF | N/A | Elaborating the connections of a closed-loop forebrain circuit in the rat: Circumscribed evidence for novel topography within a cortico-striato-pallidal triple descending projection, with thalamic feedback, to the anterior lateral hypothalamic area | | Takens定理用于评估脑电图（EEG）轨迹：大脑动力学的区域变化 | Tozzi, A. | PDF | N/A | Takens' theorem to assess EEG traces: regional variations in brain dynamics | | 整合性基因共表达网络分析揭示了与阿尔茨海默病病理相关的蛋白质编码基因和长链非编码RNA基因 | Zebardast, F. | PDF | N/A | Integrative Gene Co-expression Network Analysis Reveals Protein-Coding and lncRNA Genes Associated with Alzheimer's Disease Pathology | | 持续的干扰素信号传导导致关节炎中的感觉神经元可塑性和疼痛。 | Su, J. | PDF | N/A | Persistent interferon signaling that causes sensory neuron plasticity and pain in arthritis | | 单细胞分辨率的空间免疫组库揭示了人类免疫疾病中淋巴聚集体的空间异质性。 | Zhan, X. | PDF | N/A | Single cell resolved spatial immune repertoire unveils spatial heterogeneity of lymphoid aggregates in human immune disorders | | 系统性评估微环境依赖性转录模式及细胞间通讯 | Pareja-Lorente, E. | PDF | N/A | Systematic assessment of microenvironment-dependent transcriptional patterns and intercellular communication | | 深情凝视：心脏传入信号与迷走神经张力对视知觉的影响 | Lin, Y. | PDF | N/A | Heartfelt gaze: Cardiac afferent signals and vagal tone affect gaze perception | | 钙/钙调蛋白响应激酶II（CaMKII）枢纽域中的变构因子决定了GHB配体对CaMKIIa的选择性。 | Gauger, S. J. | PDF | N/A | Allosteric factors in the calcium/calmodulin-responsive kinase II hub domain determine selectivity of GHB ligands for CaMKIIa | | 基于靶标的环肽结合剂从头设计 | Wang, F. | PDF | N/A | Target-based de novo design of cyclic peptide binders | | BIND：通过知识图谱驱动的机器学习进行大规模生物交互网络发现 | Aamer, N. | PDF | N/A | BIND: Large-Scale Biological Interaction Network Discovery through Knowledge Graph-Driven Machine Learning | | IV型多药ABC转运蛋白中核苷酸和底物结合位点之间的双向通讯 | Perez Carrillo, V. H. | PDF | N/A | Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter | | 关于鞘磷脂纳米乳剂作为非小细胞肺癌治疗药物递送系统的机制研究 | Ramos Docampo, E. | PDF | N/A | Mechanistic Insights into Sphingomyelin Nanoemulsions as Drug Delivery Systems for Non-Small Cell Lung Cancer Therapy | | 基因语法定义了超螺旋介导的转录反馈 | Johnstone, C. P. | PDF | N/A | Gene syntax defines supercoiling-mediated transcriptional feedback | | IL-27在感染期间限制造血干细胞和祖细胞（HSPC）的分化，并防止干细胞耗竭。 | Aldridge, D. L. | PDF | N/A | IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion | | 一种新型COE-D8-磷霉素共轭物有效对抗一线抗生素耐药性尿路致病性大肠杆菌 | Ruan, L. | PDF | N/A | A Novel COE-D8-Fosfomycin Conjugate Effectively Against First-line Antibiotic Resistant Uropathogenic Escherichia coli | | 毒力调节因子bvgS是鸟博德特氏菌(Bordetella avium)在营养诱导下形成丝状体所必需的。 | Perslow, N. G. | PDF | N/A | The virulence regulator bvgS is required for nutrient-induced filamentation in Bordetella avium | | 与共受体使用相关的HIV-1包膜糖蛋白gp120和反义蛋白ASP中氨基酸替换的共变异 | Pavesi, A. | PDF | N/A | Covariation of amino acid substitutions in the HIV-1 envelope glycoprotein gp120 and the antisense protein ASP associated with coreceptor usage | | 缺乏RNase HI会影响肠炎沙门氏菌的毒力。 | Jimenez-Espadafor, J. | PDF | N/A | Lack of RNase HI affects virulence in Salmonella enterica | | 在为期3周的微重力模拟人体研究中，p53网络衰老相关基因的表达受到“摇动而非搅拌”的影响。
注：这里的“shaken, not stirred”是引用自詹姆斯·邦德（James Bond）系列电影中著名的台词，通常用于描述调制马提尼酒的方式。在这句话中，它被用作比喻，表示p53网络衰老相关基因在微重力环境下受到了某种程度的影响或干扰，但并非剧烈的改变。 | Kuznetsov, N. V. | PDF | N/A | Expression of the p53 Network Aging-associated Genes shaken, not stirred in a 3-Week Microgravity Simulation Human Study | | 5' UTR介导的eIF3在80S核糖体上的滞留促进了ER膜蛋白的共翻译折叠 | Han, B. | PDF | N/A | 5' UTR-mediated retention of eIF3 on 80S ribosomes promotes co-translational folding of ER membrane proteins | | 土地利用变化削弱了鸟类功能多样性的稳定性。 | Weeks, T. L. | PDF | N/A | Land-use change undermines the stability of avian functional diversity | | 通过结构和动态调节阐明CLIC1膜插入的机制 | Cassar, J. | PDF | N/A | Mechanistic Elucidation of CLIC1 Membrane Insertion via Structural and Dynamic Modulation | | 一种筛选方法揭示了酵母中一种未知的Mn2+依赖性内多磷酸酶活性 | Moser, S. | PDF | N/A | A Screening Approach Unveils an Unknown Mn2+ - dependent Endopolyphosphatase Activity in Yeast | | 蛋白质格式化的生物标志物富集标签用于检测癌胚抗原 | Liu, C. | PDF | N/A | Protein-Formatted Biomarker Enrichment Tag for the Detection of Carcinoembryonic Antigen | | CRISPR/Cas9基因组编辑技术生成的小鼠模型中Fzd8对骨骼发育和稳态的作用 | Lin, Z. | PDF | N/A | The Role Of Fzd8 For Bone Development And Homeostasis In A Mouse Model Generated By CRISPR/Cas9 Genome Editing | | 在猪肾动脉栓塞模型中永久性与新型可吸收微球栓塞效果的比较，用于经动脉栓塞术（TAE） | Agarwal, S. | PDF | N/A | Comparison of embolic effects between permanent and novel resorbable microspheres in a porcine renal artery embolization model for TAE | | 关于微图案化聚合物薄膜的生物降解研究 | Guerriero, I. | PDF | N/A | On the biodegradation of micropatterned polymeric film | | 使用双光子显微镜通过NAD(P)H自发荧光进行线粒体网络化的延时和体积成像 | ter Hofstede, B. | PDF | N/A | Timelapse and volumetric imaging of mitochondrial networking using NAD(P)H autofluorescence via 2-photon microscopy | | 将MC3T3-E1细胞球体封装在海藻酸盐水凝胶中产生的ECM的表征 | Boscaro, D. | PDF | N/A | Characterization of ECM produced by MC3T3-E1 cellular spheroids encapsulated in alginate hydrogel | | 迈向由生成语言模型驱动的大规模微生物组分析的生成范式 | Zhang, H. | PDF | N/A | Towards a Generative Paradigm for Large-scale Microbiome Analysis by Generative Language Model | | CARDBiomedBench：评估大型语言模型在生物医学研究中表现的基准 | Bianchi, O. | PDF | N/A | CARDBiomedBench: A Benchmark for Evaluating Large Language Model Performance in Biomedical Research | | JIND-Multi：利用多个标记数据集对单细胞RNA和ATAC数据进行自动注释 | Sancho Zamora, J. | PDF | N/A | JIND-Multi: Leveraging Multiple Labeled Datasets for Automated Annotation of Single-Cell RNA and ATAC Data | | 评估生成式人工智能模型在处理人类胰腺组织单细胞RNA测序数据中的应用 | TURGUT-OGME, S. S. | PDF | N/A | Evaluation of Generative AI Models for Processing Single-Cell RNA-Sequencing Data in Human Pancreatic Tissue | | CroCoDeEL：无需对照的宏基因组数据跨样本污染精准检测工具 | Goulet, L. | PDF | N/A | CroCoDeEL: accurate control-free detection of cross-sample contamination in metagenomic data | | 单细胞形态分析揭示了细胞死亡的见解 | Frey, B. | PDF | N/A | Single-cell morphological profiling reveals insights into cell death | | DRB7.2:DRB4介导的植物内源性反向重复双链RNA前体隔离机制 | Paturi, S. | PDF | N/A | The mechanism of DRB7.2:DRB4 mediated sequestering of endogenous inverted-repeat dsRNA precursors in plants | | 大肠杆菌的奔跑与翻滚动态由其机械特性所决定。 | Wu-Zhang, B. | PDF | N/A | Run-and-tumble dynamics of E. coli is governed by its mechanical properties | | MYCN/Aurora-A复合物是CDK12的细胞周期蛋白激活激酶。 | Mueller, M. | PDF | N/A | The MYCN/Aurora-A complex is a cyclin activating kinase for CDK12 | | PAX3-FOXO1驱动横纹肌肉瘤中可靶向的细胞状态依赖性代谢脆弱性 | Paras, K. | PDF | N/A | PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma | | 研究乳腺癌转移小鼠模型的基因组景观 | Ross, C. | PDF | N/A | Investigating the genomic landscape of mouse models of breast cancer metastasis | | 肿瘤抑制基因型影响肺癌免疫监视的程度和模式 | Adler, K. M. | PDF | N/A | Tumor suppressor genotype influences the extent and mode of immunosurveillance in lung cancer | | 通过使用TAK-981化合物靶向SAE1成分，合成抑制SUMO通路的方法能够阻碍肿瘤生长，并使胚胎性和肺泡性横纹肌肉瘤细胞系对化疗药物更为敏感。 | Codenotti, S. | PDF | N/A | Synthetic inhibition of the SUMO pathway by targeting the SAE1 component via TAK-981 compound impairs tumor growth and chemosensitizers embryonal and alveolar rhabdomyosarcoma cell lines. | | 工程化的分泌亚精胺的布拉酵母菌改善了小鼠的结肠炎和结肠癌。 | Liu, J. | PDF | N/A | Engineered spermidine-secreting Saccharomyces boulardii ameliorate colitis and colon cancer in mice | | TUB-010是一种基于Tub-tag技术的新型抗CD30抗体-药物偶联物，通过降低毒性同时保持高效力，拓宽了治疗窗口。 | Gerlach, M. | PDF | N/A | TUB-010, a novel anti-CD30 antibody-drug conjugate based on Tub-tag technology, widens the therapeutic window by reducing toxicity while maintaining high efficacy | | 柑橘整合果胶对肺癌细胞的体外活性 | Di Sano, C. | PDF | N/A | In vitro Activity of Citrus IntegroPectin against Lung Cancer Cells | | 老年大鼠经横向主动脉缩窄后左右颈动脉血流差异及海马线粒体功能改变。 | Pena, G. S. | PDF | N/A | Differential Left and Right Carotid Artery Blood Flow and Altered Hippocampal Mitochondrial Function After Transverse Aortic Constriction in Aging Rats. | | 在哺乳期而非断奶后期间暴露于高脂肪高蔗糖环境会导致葡萄糖稳态受损。 | Goergen, A. | PDF | N/A | High fat high sucrose exposure during lactation but not during the post-weaning period programs impaired glucose homeostasis | | 血液中的1-磷酸鞘氨醇（S1P）在维持血管阻力和心脏功能方面起着重要作用。 | Del Gaudio, I. | PDF | N/A | Blood-borne sphingosine 1-phosphate maintains vascular resistance and cardiac function. | | 在长期治疗的HIV感染中，α-酮戊二酸稳态的破坏促使单核细胞衍生的巨噬细胞向M2样表型转变。 | Escos, A. | PDF | N/A | Disrupted α-ketoglutarate homeostasis trains monocyte-derived macrophages towards M2-like phenotype in long-term treated HIV-infection | | 人类脊髓背角中KCC2表达减少与慢性疼痛和长期使用阿片类药物相关 | Davis, O. C. | PDF | N/A | Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use | | 皮质SST和PV中间神经元在调节自上而下的视网膜-丘脑精细化中的相互交互作用 | JIANG, Q. | PDF | N/A | Reciprocal interaction between cortical SST and PV interneurons in regulating top-down retinothalamic refinement | | NAc-DBS（伏隔核深部脑刺激）选择性地增强记忆更新，而不影响记忆检索。 | Perez-Segura, A. | PDF | N/A | NAc-DBS selectively enhances memory updating without effect on retrieval | | 7-酮胆固醇在阿尔茨海默病中促进小胶质细胞驱动的星形胶质细胞活性氧增加。 | Radhakrishnan, K. | PDF | N/A | 7-ketocholesterol contributes to microglia-driven increases in astrocyte reactive oxygen species in Alzheimer's disease | | 靶向反义寡核苷酸治疗拯救脊髓性肌萎缩症类器官中的发育异常 | Faravelli, I. | PDF | N/A | Targeted Antisense Oligonucleotide Treatment Rescues Developmental Alterations in Spinal Muscular Atrophy Organoids | | 识别Mi2的肌炎特异性自身抗体也针对共享的PHD锌指结构域中的自身免疫调节因子（AIRE）蛋白。 | Musai, J. | PDF | N/A | Myositis-specific autoantibodies recognizing Mi2 also target the autoimmune regulator (AIRE) protein at a shared PHD-zinc finger | | 作为一种增强资源获取的策略，激进干预 | Rakocinski, C. F. | PDF | N/A | Aggressive interference as a strategy for enhancing resource gain | | 以下是这段文字的中文翻译：
一个简单的年龄结构、温度依赖的褐飞虱（Nilaparvata lugens (Stal)）种群增长模型
翻译说明： 1. "simple" 翻译为 "简单的" 2. "age-structured" 翻译为 "年龄结构的" 3. "temperature-dependent" 翻译为 "温度依赖的" 4. "population growth model" 翻译为 "种群增长模型" 5. "brown rice hopper" 翻译为 "褐飞虱" 6. "Nilaparvata lugens (Stal)" 是褐飞虱的学名，保留原文
这个翻译保持了原文的科学性和准确性，同时使中文读者能够清晰理解模型的性质和研究对象。 | Wei, X. | PDF | N/A | A simple age-structured, temperature-dependent population growth model of brown rice hopper (Nilaparvata lugens (Stal)) | | 设计一种高度选择性的、基于血红蛋白的清除剂作为一氧化碳中毒解毒剂，且无升压效应。 | Dent, M. R. | PDF | N/A | Engineering a highly selective, hemoprotein-based scavenger as a carbon monoxide poisoning antidote with no hypertensive effect | | 丙泊酚治疗改变了MDA-MB-231乳腺癌细胞的代谢状态 | Tasmi, T. A. | PDF | N/A | Propofol Treatment Alters the Metabolic State of MDA-MB-231 Breast Cancer Cells | | 开发一种高通量形态学检测方法，用于评估间充质基质细胞来源的细胞外囊泡对脑周细胞分泌表型的调节作用 | Campagna, C. E. | PDF | N/A | Development of a High-throughput Morphological Assay for Evaluating Mesenchymal Stromal Cell-derived Extracellular Vesicle Modulation of Brain Pericyte Secretory Phenotype | | SOuLMuSiC：一种预测突变对蛋白质溶解度影响的计算工具 | Attanasio, S. | PDF | N/A | SOuLMuSiC: A Computational Tool for Predicting the Impact of Mutations on Protein Solubility | | PLMFit：利用蛋白质语言模型进行蛋白质工程的迁移学习基准测试 | Bikias, T. | PDF | N/A | PLMFit : Benchmarking Transfer Learning with Protein Language Models for Protein Engineering |