BioRxiv 2025-01-21 Papers

标题	作者	PDF链接	代码仓库	Title
解开具有多种中间神经元类别的皮质回路中的稳定性和增益调节	Bos, H.	PDF	N/A	Untangling stability and gain modulation in cortical circuits with multiple interneuron classes
深入剖析癌症蛋白质组，从标准RNA制备试剂盒的流穿液中获取，用于精准肿瘤学	Mundt Madsen, F.	PDF	N/A	In depth profiling of the cancer proteome from the flowthrough of standard RNA-preparation kits for precision oncology
研究年龄和听力损失对语音清晰度和振幅调制频率选择性的影响	Regev, J.	PDF	N/A	Investigating the effects of age and hearing loss on speech intelligibility and amplitude modulation frequency selectivity
“暗分类学”：一种新协议，旨在克服暗分类群的分类障碍并扩大生物多样性评估的分类群基础	Meier, R.	PDF	N/A	"Dark taxonomy": a new protocol for overcoming the taxonomic impediments for dark taxa and broadening the taxon base for biodiversity assessment
对新加坡（面积730平方公里）的蕈蚊科（双翅目：毛蚊总科）进行综合分类研究，揭示了115个新物种。	Amorim, D. d. S.	PDF	N/A	An integrative taxonomic treatment of the Mycetophilidae (Diptera: Bibionomorpha) from Singapore reveals 115 new species on 730km2
过量的新生儿睾酮会导致野生型小鼠出现雄性特有的社交和恐惧记忆缺陷。	Quinones-Labernik, P.	PDF	N/A	Excess neonatal testosterone causes male-specific social and fear memory deficits in wild-type mice
基于光泵磁力计的脑磁图技术向人类早期生命研究的边界推进	Corvilain, P.	PDF	N/A	Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life
集体定向记忆控制上皮细胞迁移的范围	Canever, H.	PDF	N/A	Collective directional memory controls the range of epithelial cell migration
揭示P450还原酶在除草剂代谢抗性机制中的作用	Rigon, C. A. G.	PDF	N/A	Unraveling the Role of P450 Reductase in Herbicide Metabolic Resistance Mechanism
额叶皮层中精神努力的神经代谢预测因素	Barakat, A.	PDF	N/A	Neurometabolic predictors of mental effort in the frontal cortex
上皮细胞中的趋同基因表达揭示了子宫容受性的进化	Brulport, A.	PDF	N/A	Convergent gene expression in epithelial cells illuminates the evolution of uterine receptivity
脊髓损伤中星形胶质细胞向神经元重编程的挑战与效能：体外研究见解与体内结果	NICEFORO, A.	PDF	N/A	Challenges and Efficacy of Astrocyte-to-Neuron Reprogramming in Spinal Cord Injury: In Vitro Insights and In Vivo Outcomes
人类遗传变异rs6190揭示了Foxc1和Arid5a作为糖皮质激素受体在肌肉中的新型促代谢靶点。	Prabakaran, A. D.	PDF	N/A	The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle.
转录组范围内通过脱氨酶和阅读蛋白辅助测序鉴定5-甲基胞嘧啶	Zhou, J.	PDF	N/A	Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing
以下是这段英文的中文翻译：

稳健、高通量且时间可调控的roxCre和loxCre报告系统用于体内基因修饰

翻译解释： - robust：稳健的，指系统稳定可靠。 - high-throughput：高通量的，指系统能够处理大量样本或数据。 - temporally regulated：时间可调控的，指系统能够根据时间进行精确调控。 - roxCre and loxCre reporting systems：roxCre和loxCre报告系统，这是两种常用于基因编辑的工具。 - genetic modifications in vivo：体内基因修饰，指在活体生物体内进行的基因编辑操作。

希望这个翻译对你有帮助！ | Shi, M. | PDF | N/A | The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo | | TRPg通过Dh44神经内分泌细胞调节脂质代谢。 | Nath, D. K. | PDF | N/A | TRPg regulates lipid metabolism through Dh44 neuroendocrine cells | | 评估使用诱捕法在串联质谱分析中的假发现率控制 | Wen, B. | PDF | N/A | Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment | | 噬菌体组从肠道向循环系统的转移及其受人类免疫系统的调控 | Szymczak, A. | PDF | N/A | Phageome transfer from gut to circulation and its regulation by human immunity | | 青少年期酒精暴露促进机械性异常疼痛并改变从基底外侧杏仁核到前额叶皮层前肢区的突触功能 | Obray, J. D. | PDF | N/A | Adolescent Alcohol Exposure Promotes Mechanical Allodynia and Alters Synaptic Function at Inputs from the Basolateral Amgydala to the Prelimbic Cortex | | 可微分的Gillespie算法用于模拟化学动力学、参数估计以及设计合成生物电路 | Rijal, K. | PDF | N/A | A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits | | Rep结构由开放和闭合状态之间的亚稳态中间体组成，这些中间体的过渡动力学受离子环境的调节。 | Howard, J. A. L. | PDF | N/A | Rep structures comprise metastable intermediates between open and closed states whose transitional kinetics are tuned by the ionic environment | | 为巴甫洛夫关联的学习和消退而存在的空间组织化纹状体广泛乙酰胆碱动态变化 | Bouabid, S. | PDF | N/A | Distinct spatially organized striatum-wide acetylcholine dynamics for the learning and extinction of Pavlovian associations | | 《细胞色素c的折叠与稳定性全面指南及其对疾病的影响》 | Yousaf, M. A. | PDF | N/A | A comprehensive guide through the fold and stability of cytochrome c with implications for disease | | 通过基于组装的策略适应原始读数和蛋白质，实现系统发育关系的可靠推断 | Li, Y. | PDF | N/A | Reliable inference of phylogenomic relationship via assembly-based strategy accommodating raw reads and proteins | | 使用沉积古DNA数据检测生态相互作用的挑战 | Callahan, F. M. | PDF | N/A | Challenges in detecting ecological interactions using sedimentary ancient DNA data | | 重新思考大规模系统基因组学：使用EukPhylo v1.0，一个灵活的工具包，以实现系统发育信息指导的数据管理和多样化真核生物谱系的分析 | Katz, L. A. | PDF | N/A | Rethinking large scale phylogenomics with EukPhylo v1.0, a flexible toolkit to enable phylogeny-informed data curation and analyses of diverse eukaryotic lineages | | 行为差异鹿鼠下丘脑视前区的细胞进化 | Chen, J. | PDF | N/A | Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice | | 描述一种新型极端嗜好绿色藻类——太平洋衣藻（Chlamydomonas pacifica），及其作为生物技术宿主的潜力 | Dutra Molino, J. V. | PDF | N/A | Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host | | 早期发育及脑微结构与功能连接组的共演化：一项针对早产儿和足月儿的多模态MRI研究 | Gondova, A. | PDF | N/A | Early development and co-evolution of microstructural and functional brain connectomes: A multi-modal MRI study in preterm and full-term infants | | 使用对比学习进行遗传数据的降维 | Thor, F. | PDF | N/A | Dimensionality Reduction of Genetic Data using Contrastive Learning | | 探索顺式作用基因调控的极限：基于等位基因失衡数量性状位点的模型研究 | Seoighe, C. | PDF | N/A | Probing the limits of cis-acting gene regulation using a model of allelic imbalance quantitative trait loci | | 提高分子字符串表示在生成化学中的可靠性 | Reboul, E. | PDF | N/A | Improving the reliability of molecular string representations for generative chemistry | | 理解神经元多样性：输入动态与滤波的作用 | Joshi, N. | PDF | N/A | Understanding Neuronal Diversity: Role of Input Dynamics and Filtering | | 计算识别空间转录组数据中的迁移T细胞 | Zhong, L. | PDF | N/A | Computational Identification of Migrating T cells in Spatial Transcriptomics Data | | 在时间变化的环境中，优势逆转维持了大效应抗性多态性。 | Karageorgi, M. | PDF | N/A | Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments | | 克服艰难梭菌分型中的重复性和变异性挑战 | Bravo-Anton, L. | PDF | N/A | Overcoming challenges of reproducibility and variability for the Clostridioides difficile typification | | 纳米生理学方法揭示斑马鱼视网膜双极带状突触间钙微域的多样性 | Rameshkumar, N. | PDF | N/A | Nanophysiology Approach Reveals Diversity in Calcium Microdomains across Zebrafish Retinal Bipolar Ribbon Synapses | | 脂多糖（LPS）和志贺毒素暴露对培养的人脐静脉内皮细胞RNA表达程序的协同作用。 | Svilar, D. | PDF | N/A | Synergy of LPS and Shiga-toxin exposure on the RNA expression program of cultured human umbilical vein endothelial cells. | | 以下是这段英文的中文翻译：

临床相关伯克霍尔德菌属β-内酰胺酶的动态差异

翻译说明： - "Dynamic Differences" 翻译为“动态差异”。 - "Clinically relevant" 翻译为“临床相关的”。 - "Pen β-Lactamases" 翻译为“β-内酰胺酶”。 - "Burkholderia spp." 翻译为“伯克霍尔德菌属”。

希望这对你有帮助！如果有其他问题，请随时告诉我。 | Gu, J. | PDF | N/A | Dynamic Differences in Clinically relevant Pen β-Lactamases from Burkholderia spp. | | 将深度学习应用于视频分析作为测量家禽中大肠杆菌感染的工具 | Scheidwasser, N. | PDF | N/A | Deep learning from videography as a tool for measuring E. coli infection in poultry | | 在年轻健康成年人中，观察协调动作和进行适应性单腿坐站运动的运动想象时，皮质脊髓兴奋性得到增强。 | Valappil, A. C. | PDF | N/A | Corticospinal excitability is facilitated during coordinative action observation and motor imagery of adapted single-leg sit-to-stand movements in young healthy adults | | 在存在未知个体的情况下对单个动物的声学识别 | Huang, L. | PDF | N/A | Acoustic Recognition of Individual Animals in thePresence of Unknown Individuals | | SAR11菌株的栖息地特异性与少数受到高度选择的基因相关。 | Tucker, S. J. | PDF | N/A | Habitat-specificity in SAR11 is associated with a handful of genes under high selection | | 化学位移和弛豫正则化提高了1H磁共振波谱分析的准确性。 | Wilson, M. | PDF | N/A | Chemical shift and relaxation regularisation improve the accuracy of 1H MR spectroscopy analysis | | 古代基因簇启动单萜吲哚生物碱的生物合成及C3立体化学反转 | Hwang, J. | PDF | N/A | Ancient gene clusters initiate monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion | | 手动与自动注释转座子元素的比较：以果蝇（Drosophila melanogaster）和白纹伊蚊（Aedes albopictus）为例，平衡准确性与生物学相关性 | Carrasco-Valenzuela, T. | PDF | N/A | Manual versus automatic annotation of transposable elements: case studies in Drosophila melanogaster and Aedes albopictus, balancing accuracy and biological relevance | | 在急性环境挑战下斑马鱼尾部神经分泌系统中激素基因表达的变化 | Bichon, B. | PDF | N/A | Hormone gene expression changes in the zebrafish caudal neurosecretory system under acute environmental challenges | | 《Streptocarpus sect. Saintpaulia（非洲紫罗兰）中不稳定的花青素着色现象源于单一MYB基因的转录选择性》 | Kurata, D. | PDF | N/A | Unstable anthocyanin pigmentation in Streptocarpus sect. Saintpaulia (African violet) is due to transcriptional selectivity of a single MYB gene | | Oncodrive3D：快速准确地检测正选择下的体细胞突变结构簇 | Pellegrini, S. | PDF | N/A | Oncodrive3D: Fast and accurate detection of structural clusters of somatic mutations under positive selection | | 在噬菌体诱导过程中，Cro2和CI2与OR操作子结合在控制溶原稳定性中的作用 | Pang, Y. | PDF | N/A | Roles of Cro2 and CI2 binding to OR operators in controlling lysogeny stability during prophage induction | | 甲氨蝶呤治疗下类风湿性关节炎的时间分辨免疫动态 | Preglej, T. | PDF | N/A | Time-resolved immune dynamics in rheumatoid arthritis under Methotrexate therapy | | Wnt信号活性与Sox2转录因子水平的比率预测了神经中胚层命运潜能。 | Morabito, R. D. | PDF | N/A | The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential | | 将系统性硬化症中的空间分辨转录组进行映射 | Li, Z. | PDF | N/A | Mapping spatially-resolved transcriptomes in systemic sclerosis | | CARDBiomedBench：评估大型语言模型在生物医学研究中表现的基准 | Bianchi, O. | PDF | N/A | CARDBiomedBench: A Benchmark for Evaluating Large Language Model Performance in Biomedical Research | | 组蛋白去乙酰化酶-1是粗糙脉孢菌表观基因组稳定所必需的 | Ebot-Ojong, F. | PDF | N/A | Histone deacetylase-1 is required for epigenome stability in Neurospora crassa | | hmde: 微分方程的分层方法 | O'Brien, T. A. | PDF | N/A | hmde: Hierarchical Methods for Differential Equations | | AuthormetriX：从Scopus语料库中自动计算个体作者的非通胀性信用分配方案和合作指标 | Adeosun, S. O. | PDF | N/A | AuthormetriX: Automated Calculation of Individual Authors' Non-Inflationary Credit-Allocation Schemas' and Collaboration Metrics from a Scopus Corpus | | H3K4甲基化促进的转录记忆确保了合子基因组的忠实激活和胚胎发育 | Oak, M. S. | PDF | N/A | H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development | | 一种用于整合蛋白质功能多模态数据的对抗性方案 | Nasser, R. | PDF | N/A | An adversarial scheme for integrating multi-modal data on protein function | | AI驱动的发现：宿主硫氧还蛋白作为CRISPR增强剂，促进噬菌体编码的微型Cas12黑客核酸酶的功能 | Wang, Z. | PDF | N/A | AI-driven discovery of host thioredoxin as a CRISPR enhancer of phage-encoded miniature Cas12 hacker nuclease | | 假定的肺炎克雷伯菌生态梯度 | Liu, S. | PDF | N/A | A putative ecocline in Klebsiella pneumoniae | | 产后人类内颅和大脑结构中大小与形状的相互作用 | Takagi, K. | PDF | N/A | Postnatal interaction of size and shape in the human endocranium and brain structures | | baal-nf 识别出那些降低转录因子结合亲和力的基序破坏变异。 | Roskams-Hieter, B. | PDF | N/A | baal-nf identifies motif-disrupting variants that decrease transcription factor binding affinity | | 计算设计的靶向RAD51-BRCA2相互作用的适配体抑制RAD51核募集 | Miliordini, G. | PDF | N/A | Computationally-designed aptamers targeting RAD51-BRCA2 interaction inhibit RAD51 nuclear recruitment | | ESMAdam：一种即插即用的通用蛋白质集合生成器 | Yu, Z. | PDF | N/A | ESMAdam: a plug-and-play all-purpose protein ensemble generator | | 底物识别的两个阶段决定了大肠杆菌MetNI-Q ABC转运系统的选择性 | Yang, J. G. | PDF | N/A | Two stages of substrate discrimination dictate selectivity in the E. coli MetNI-Q ABC transporter system | | D类β-内酰胺酶中的标准化残基编号与二级结构命名法 | Stasyuk, A. | PDF | N/A | Standardized Residue Numbering and Secondary Structure Nomenclature in the Class D β-Lactamases | | 多区域脑类器官：融合了大脑、内皮和中后脑组件的融合类器官 | Kshirsagar, A. | PDF | N/A | Multi-Region Brain Organoid: Fusion Organoid with Cerebral, Endothelial and Mid-Hindbrain Components | | 通过HighFold2预测含有非天然氨基酸的环肽结构 | Zhu, C. | PDF | N/A | Predicting the structures of cyclic peptides containing unnatural amino acids by HighFold2 | | 以下是将这段英文翻译成中文的结果：

一个链接基因组学测序和质谱多模态数据集及模型，用于简化微生物菌株库中天然产物的发现。

翻译解释： - Linked Genomics Sequencing and Mass Spectrometry: 链接基因组学测序和质谱 - multi-modal dataset: 多模态数据集 - models: 模型 - Streamlined Natural Products Discovery: 简化的天然产物发现 - Microbial Strain Libraries: 微生物菌株库

深层永久冻土中的微生物复苏与生长速率：阿拉斯加福克斯永久冻土研究隧道的脂质稳定同位素探测结果

翻译说明： - Microbial Resuscitation：微生物复苏，指微生物从休眠状态恢复活性的过程。 - Growth Rates：生长速率，指微生物繁殖或代谢的速度。 - Deep Permafrost：深层永久冻土，指地下较深处的永久冻结层。 - Lipid Stable Isotope Probing：脂质稳定同位素探测，一种用于研究微生物代谢活动的技术。 - Permafrost Research Tunnel：永久冻土研究隧道，位于阿拉斯加福克斯的一个研究设施。

男性和女性参与者在步行足球训练期间的外部与内部负荷概况

这个标题描述了一项研究或分析，旨在探讨男性和女性在步行足球训练中的外部负荷（如运动量、速度、距离等）和内部负荷（如心率、疲劳程度等）的表现和差异。 | da Costa, J. A. H. C. | PDF | N/A | External and Internal Load Profiles of Male and Female Participants during a Walking Football Practice | | 开发一种新型小鼠模型用于研究支架内新生动脉粥样硬化 | Liu, J. | PDF | N/A | Development of a novel murine model of in-stent neoatherosclerosis | | 系统遗传学方法揭示了蛋白酶体因子在心脏发育和先天性心脏缺陷中的作用。 | Farr, G. H. | PDF | N/A | A systems genetics approach identifies roles for proteasome factors in heart development and congenital heart defects | | Seo1p是一种在酵母和真菌中具有高亲和力的γ-谷氨酰甲硫氨酸（gamma-Glu-met）二肽的质膜转运蛋白。 | Dubey, P. | PDF | N/A | Seo1p, a high affinity, plasma membrane transporter of the gamma-Glu-met dipeptide in yeasts and fungi | | 倒位在高度混合的欧洲沙丁鱼（Sardina pilchardus）的进化中占据主导地位 | Sabatino, S. J. | PDF | N/A | Inversions Dominate Evolution in the Highly Admixed European Sardine (Sardina pilchardus) | | 社会许可压力与澳大利亚公众对野犬致命控制的支持。 | Pearson, A. I. | PDF | N/A | Social License Pressure and Public Support for the Lethal Control of Dingoes in Australia. | | OT-Mation：一个开源代码，用于将CSV文件解析为Python脚本，以控制OT-2液体处理机器人。 | Laverick, A. | PDF | N/A | OT-Mation: an open-source code for parsing CSV files into python scripts for control of OT-2 liquid handling robotics | | 炎症小体适配蛋白ASC在肥胖期间引发的菌群失调导致免疫代谢紊乱 | Martinez-Garcia, J. J. | PDF | N/A | The inflammasome adaptor protein ASC triggers immunometabolic dysregulation induced by dysbiosis during obesity | | 优化生物力学性能的线圈增强多层血管移植物的先进制造 | Robinson, A. | PDF | N/A | Advanced Manufacturing of Coil-Reinforced Multilayer Vascular Grafts to Optimize Biomechanical Performance | | Parapipe：处理寄生虫NGS数据集的流程及其在隐孢子虫中的应用 | Morris, A. V. | PDF | N/A | Parapipe: a Pipeline for Handling Parasite NGS Datasets and its Application to Cryptosporidium | | CPI-Pred：一个用于预测化合物-蛋白质相互作用功能参数的深度学习框架 | Xu, Z. | PDF | N/A | CPI-Pred: A deep learning framework for predicting functional parameters of compound-protein interactions | | 通过Householder反射的反射仿制品：在蛋白质组学和遗传精细定位中的应用 | Guan, Y. | PDF | N/A | Reflection Knockoffs via Householder Reflection: Applications in Proteomics and Genetic Fine Mapping | | GLUT5装甲增强了在葡萄糖限制条件下过继性T细胞疗法的抗肿瘤活性。 | Page, R. | PDF | N/A | GLUT5 armouring enhances adoptive T cell therapy anti-tumour activity under glucose-limiting conditions | | 在变化环境中的物种分布范围和生态位的演变 | Polechova, J. | PDF | N/A | Evolution of species' range and niche in changing environments | | 估计强化学习中的运动探索 | Zai, A. T. | PDF | N/A | Estimating the motor exploration in reinforcement learning | | 声音增强的睡眠深度减少创伤性脑损伤的损害和后遗症，并支持小胶质细胞的反应 | Moreira, C. C. G. | PDF | N/A | Sound-Enhanced Sleep Depth Reduces Traumatic Brain Injury Damage and Sequelae and Supports Microglial Response | | 每日间歇性禁食在无癫痫发作的临床前模型中是一种有效的多尺度治疗方法。 | Rulhe, C. | PDF | N/A | Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy | | 鼻至脑的治愈之路：缺氧预处理的间充质干细胞促进缺氧缺血性脑病大鼠的恢复 | Serrenho, I. | PDF | N/A | Nose-to-Brain Healing: Hypoxia-Preconditioned Mesenchymal Stem Cells Prompt Recovery in Hypoxic-Ischemic Encephalopathy Rats | | GAL-101能够防止β淀粉样蛋白在两种不同类型的视网膜细胞中引起的膜电位去极化。 | Pizzi, E. | PDF | N/A | GAL-101 prevents amyloid beta-induced membrane depolarization in two different types of retinal cells | | DNA甲基化作为STX6及其他额颞叶变性遗传风险相关位点失调的贡献者 | Rambarack, N. | PDF | N/A | DNA methylation as a contributor to dysregulation of STX6 and other frontotemporal lobar degeneration genetic risk-associated loci | | 平息风暴：低氧作为增强UC-MSC治疗新生儿缺氧缺血性脑病的策略 | Serrenho, I. | PDF | N/A | Quieting the Storm: Hypoxia as a Strategy to Boost UC-MSC Therapies for Neonatal Hypoxic-Ischemic Encephalopathy | | I型nNOS神经元协调皮质神经活动和血管运动 | Turner, K. | PDF | N/A | Type-I nNOS neurons orchestrate cortical neural activity and vasomotion | | p16.1和p16.2，作为新的造血干细胞和祖细胞（HSPC）标记物，在斑马鱼的T细胞淋巴生成过程中扮演着冗余的角色。 | Gomez, E. | PDF | N/A | p16.1 and p16.2, new HSPC markers, play redundant roles in zebrafish T-cell lymphopoiesis | | 通过Notch对神经前体细胞进行表观遗传学预编程，增强了Sonic hedgehog信号通路，并建立了胶质细胞生成的能力。 | Tran, L. N. | PDF | N/A | Epigenetic priming of neural progenitors by Notch enhances Sonic hedgehog signaling and establishes gliogenic competence | | 输注同种异体小鼠HOD红细胞优先诱导低亲和力、短寿命的IgG抗体，这些抗体的产生不依赖于生发中心。 | Medved, J. | PDF | N/A | Transfusion of allogenic murine HOD red blood cells preferentially induces low-affinity, short-lived IgG antibodies that are germinal center independent | | I型干扰素-IL-27轴促进mRNA疫苗诱导的CD8+ T细胞反应 | Phan, A. T. | PDF | N/A | The type I IFN-IL-27 axis promotes mRNA vaccine-induced CD8+ T cell responses | | 使用景观生物多样性指标评估再野化：以克内普庄园与布斯比荒野农业基线进行时空对比 | Pates, N. J. | PDF | N/A | Using landscape biodiversity metrics to assess rewilding: a space-for-time comparison between the Knepp Estate and an agricultural baseline at Boothby Wildland | | 难以采样的物种对土地利用变化更为敏感：对全球生物多样性指标的影响 | Gutierrez-Arellano, C. | PDF | N/A | Hard-to-sample species are more sensitive to land-use change: implications for global biodiversity metrics | | 解码瓢虫的颜色：颜色产生的结构机制与色素调控。 | CARRADA, M. | PDF | N/A | Decoding ladybird's colours: structural mechanisms of colour production and pigment modulation. | | 胆碱能动态在海马隔系统中为空间新颖性提供了阶段性多路复用信号，并与行为状态相关。 | Moghadam, F. F. | PDF | N/A | Cholinergic dynamics in the septo-hippocampal system provide phasic multiplexed signals for spatial novelty and correlate with behavioral states | | 常规核小体与CENP-A核小体在溶液中的构象差异，在高压下的可逆变形作用下更加显著。 | Gupta, K. | PDF | N/A | Solution conformational differences between conventional and CENP-A nucleosomes are accentuated by reversible deformation under high pressure | | 评估生成扩散模型在跨尺度和全原子分辨率下对折叠和无序蛋白质状态的增强采样能力 | Bera, P. | PDF | N/A | Assessing Generative Diffusion Models for Enhanced Sampling of Folded and Disordered Protein States Across Scales and in All-atom Resolution | | 使用马尔可夫状态模型揭示组蛋白尾部的构象动力学 | Patel, R. | PDF | N/A | Unveiling the Conformational Dynamics of the Histone Tails Using Markov State Modeling | | ADAR1通过MDM2调控脂质重塑以决定铁死亡敏感性 | Kung, C.-P. | PDF | N/A | ADAR1 Regulates Lipid Remodeling through MDM2 to Dictate Ferroptosis Sensitivity | | 产前大麻素暴露影响年轻雄性和雌性大鼠的中枢心肺控制 | Patrone, L. G. A. | PDF | N/A | Prenatal cannabinoid exposure affects central cardiorespiratory control in young male and female rats | | 大嘴巴的劣势：昆虫体型大小与微塑料摄入之间的关系 | Ritchie, M. W. | PDF | N/A | The disadvantage of having a big mouth: the relationship between insect body size and microplastic ingestion | | 高通量评估运动诱导的适应及健康和衰老中的肌肉功能 | Malita, A. | PDF | N/A | High-throughput assessment of exercise-induced adaptations and muscle function in health and ageing | | CHD2剂量将自噬溶酶体途径与疾病和进化中的皮质成熟联系起来 | Leonardi, O. | PDF | N/A | CHD2 Dosage Ties Autolysosomal Pathway to Cortical Maturation in Disease and Evolution | | 慢性社会不稳定压力对雄性和雌性小鼠前背侧终纹床核的行为和转录组的影响存在差异。 | Degroat, T. J. | PDF | N/A | Chronic social instability stress differentially affects the behavior and the transcriptome of the anterodorsal bed nucleus of the stria terminalis between male and female mice | | 小鼠感觉运动皮层中体感信息的群体水平编码 | Park, S. | PDF | N/A | Population-level encoding of somatosensation in mouse sensorimotor cortex | | 人类视觉皮层中的空间频率图谱：一项复制与扩展研究 | Ha, J. | PDF | N/A | Spatial Frequency Maps in Human Visual Cortex: A Replication and Extension | | 工作记忆在学习过程中塑造了人类脑电图中的神经几何结构。 | Wojcik, M. J. | PDF | N/A | Working memory shapes neural geometry in human EEG over learning | | 单一背侧迷走神经复合体回路介导对GLP1R激动剂的厌恶和厌食反应 | Yacawych, W. T. | PDF | N/A | A single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists | | 抑制血管紧张素转换酶的N端催化域可以防止脑组织中内源性阿片类物质的降解。 | Hanak, F. | PDF | N/A | Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue | | 抗Caspr2抗体的异质性：特异性与致病性 | Su, J. | PDF | N/A | Heterogeneity of anti-Caspr2 antibodies: specificity and pathogenicity | | 移植前靶向TNFRSF25和CD25可刺激目标组织中的受体调节性T细胞（Tregs），从而改善造血干细胞移植（HSCT）后的移植物抗宿主病（GVHD）。 | McManus, D. | PDF | N/A | Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT | | 一种非人灵长类动物模型模拟了人类先天性巨细胞病毒感染，并揭示了垂直传播结果的全谱。 | Manuel, T. D. | PDF | N/A | A nonhuman primate model mirrors human congenital cytomegalovirus infection and reveals a spectrum of vertical transmission outcomes | | 定义灵长类动物卵巢储备的细胞和分子起源 | Wamaitha, S. E. | PDF | N/A | Defining the cell and molecular origins of the primate ovarian reserve | | 四核苷酸频率区分环境微生物组中的基因组边界和代谢策略 | Kellom, M. | PDF | N/A | Tetranucleotide frequencies differentiate genomic boundaries and metabolic strategies across environmental microbiomes | | 表观遗传因子Zrf1在中肠再生过程中调节肠道干细胞的增殖 | Li, J. S. S. | PDF | N/A | The epigenetic factor Zrf1 regulates intestinal stem cell proliferation during midgut regeneration | | 大肠杆菌中兼职蛋白的近端关系：数学基因组学视角 | NAWN, D. | PDF | N/A | Proximal relationships of moonlighting Proteins in Escherichia coli: a mathematical genomic perspective | | 上呼吸道上皮单细胞图谱揭示了细胞类型和模式策略的异质性 | Sun, X. | PDF | N/A | A Single-Cell Atlas of the Upper Respiratory Epithelium Reveals Heterogeneity in Cell Types and Patterning Strategies | | 探索非裔美国女性中高血压与肾功能之间的转录组学交叉景观 | Abbas, M. | PDF | N/A | Intersecting Transcriptomic Landscapes of Hypertension and Kidney Function in African American Women | | 在Furfurilactobacillus中发现了一个分歧的肉毒杆菌神经毒素样基因簇 | Wei, X. | PDF | N/A | Identification of a divergent botulinum neurotoxin like gene cluster in Furfurilactobacillus | | 使用可解释的机器学习方法解码PTEN错义突变在癌症和自闭症谱系障碍中的机制 | Yang, M. | PDF | N/A | Decoding Mechanisms of PTEN Missense Mutations in Cancer and Autism Spectrum Disorder using Interpretable Machine Learning Approaches | | 在牛津纳米孔技术测序仪上使用R2C2和Chopper方法对完整质粒进行测序和组装 | Schimke, K. D. | PDF | N/A | Sequencing and assembling complete plasmids on Oxford Nanopore Technology Sequencers using R2C2 and Chopper | | 静态三维结构决定间期染色体远端位点对之间的快速动态 | Shi, G. | PDF | N/A | Static Three-Dimensional Structures Determine Fast Dynamics Between Distal Loci Pairs in Interphase Chromosomes | | 二维蛋白质二聚化的结合亲和力受益于焓的稳定作用。 | Jhaveri, A. | PDF | N/A | Binding affinities for 2D protein dimerization benefit from enthalpic stabilization | | 对肠道中吞咽空气量的量化研究发现，睡眠时空气量较低可能会减少有氧消化，这解释了为什么晚餐后短时间内入睡与夜间反流有关。 | Hurr, T. J. | PDF | N/A | Quantification of the volume of swallowed air in the gut finds low volumes when asleep may reduce aerobic digestion and explain why short dinner to sleep times are associated with nocturnal reflux | | 监测杀菌剂抗性频率——以大麦网斑病为例 | Knight, N. L. | PDF | N/A | Monitoring fungicide resistance frequencies -- a case study of barley net blotch | | 沿着厚壁升支的不同细胞类型表达单价和二价阳离子转运的途径。 | Bahena-Lopez, J. | PDF | N/A | Distinct cell types along thick ascending limb express pathways for monovalent and divalent cation transport | | 衰老、耐力训练和去神经对骨骼肌先天免疫信号的影响 | Khemraj, P. | PDF | N/A | Effect of aging, endurance training, and denervation on innate immune signaling in skeletal muscle | | 针对APOE3-Christchurch纯合子星形胶质细胞的阿尔茨海默病保护机制 | Tian, X. | PDF | N/A | Protective mechanisms against Alzheimer's Disease in APOE3-Christchurch homozygous astrocytes | | 使用实验设计进行人类原代B细胞培养的多参数优化 | Rovsing, A. B. | PDF | N/A | Multiparametric optimization of human primary B-cell cultures using Design of Experiments | | 比较基于mRNA、腺病毒血清型25和黄热病疫苗株嵌合体的蜱传脑炎病毒候选疫苗 | Kuznetsova, N. A. | PDF | N/A | Comparison candidate Tick-borne encephalitis virus vaccines based on mRNA, adenovirus serotype 25 and chimera of YFV vaccine strain | | 瞬态pH变化驱动酶-聚合物凝聚体中的液泡形成 | Modi, N. | PDF | N/A | Transient pH changes drive vacuole formation in enzyme-polymer condensates | | 通过47个高分辨率基因组组装揭示白蚁进化 | Liu, C. | PDF | N/A | Unravelling termite evolution with 47 high-resolution genome assemblies | | 最初为工业应用合成的光活性化合物的新型抗菌活性 | Ezquerra-Aznarez, J. M. | PDF | N/A | Novel antimicrobial activity of photoactive compounds originally synthesized for industrial applications | | 木霉菌（Trichoderma atroviride，属于肉座菌目：肉座菌科）对白纹伊蚊（Aedes albopictus，属于双翅目：蚊科）的杀幼虫活性研究 | Hayes, D. T. | PDF | N/A | Larvicidal activity of Trichoderma atroviride (Hypocreales: Hypocreaceae) against Aedes albopictus (Diptera: Culicidae) | | 肠道竞争动态：活菌疗法的效果受微生物组复杂性、饮食和治疗性转基因的影响 | Siguenza, N. | PDF | N/A | Gut Competition Dynamics of Live Bacterial Therapeutics Are Shaped by Microbiome Complexity, Diet, and Therapeutic Transgenes | | 开发用于拉科罗斯病毒检测的RT-RPA检测方法为小鼠年龄依赖性神经侵袭提供了见解 | Lumkong, L. | PDF | N/A | Development of an RT-RPA assay for La Crosse virus detection provides insights into age-dependent neuroinvasion in mice | | 利用内源性Cas9基因编辑技术对鼠李糖乳杆菌GG（LGG）进行精准食品发酵和活体生物治疗的研究 | Xie, Z. | PDF | N/A | Exploiting Endogenous Cas9-Based Genome Editing of Lacticaseibacillus rhamnosus GG (LGG) for Precision Food Fermentation and Live Biotherapeutics | | 一个类似于LexA的阻遏蛋白和全局性的H-NS样调节因子使得环境中的假单胞菌能够精细调控R-tailocin的表达。 | Heiman, C. M. | PDF | N/A | A LexA-like repressor and global H-NS-like regulators enable the fine-tuning of R-tailocin expression in environmental Pseudomonas | | 人类母乳低聚糖通过梭菌属物种的代谢抑制炎症和病原体生长 | Chapman, J. A. | PDF | N/A | Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth | | 宿主环境塑造丝虫寄生虫的适应性与沃尔巴克氏体共生动态 | FERCOQ, F. | PDF | N/A | Host environment shapes filarial parasites fitness and Wolbachia endosymbionts dynamics | | 局部核仁监视机制维持rDNA稳定性 | Liu, R. | PDF | N/A | Local nucleolar surveillance mechanisms maintain rDNA stability | | 诊断感染辣椒和番茄植物的黄单胞菌的特异性遗传标记 | Can, A. | PDF | N/A | The Specific Genetic Markers to Diagnose Xanthomonads Infecting Pepper and Tomato Plants | | 通过限制基因编辑表达的组织范围来最小化基因编辑的脱靶效应 | Kim, N.-G. | PDF | N/A | Minimization of gene editing off-target effects by tissue restriction of expression | | 有证据表明，SARS-CoV-2病毒的刺突蛋白（S蛋白）可能针对多种细胞骨架及细胞骨架相关蛋白的卷曲螺旋区域。 | Brezellec, P. | PDF | N/A | Evidence suggests that the SARS-CoV-2 Spike (S) protein may target coiled-coil regions of numerous cytoskeletal and cytoskeleton-associated proteins | | 磷酸肌醇和Collybistin依赖的Gephyrin突触聚集 | Burdina, N. | PDF | N/A | Phosphoinositide- and Collybistin-Dependent Synaptic Clustering of Gephyrin | | 糖生物学中的蛋白质-聚糖相互作用及跨手性识别的原子级机制 | Carpenter, E. J. | PDF | N/A | Atom-level Machine of Protein-glycan Interactions and Cross-chiral Recognition in Glycobiology | | 副斑蛋白NONO通过变构刺激NSD1来调节活性染色质 | Hsu, C.-I. | PDF | N/A | Paraspeckle Protein NONO Regulates Active Chromatin by Allosterically Stimulating NSD1 | | 氮酶催化辅因子的分子分选 | Salinero-Lanzarote, A. | PDF | N/A | Molecular sorting of nitrogenase catalytic cofactors | | USP1作为HSFA2的伴侣蛋白，在拟南芥的热启动过程中起着至关重要的作用。 | Hirt, H. | PDF | N/A | USP1 acts as a chaperone for HSFA2 and plays a crucial role in thermopriming in Arabidopsis | | 一氧化碳暴露刺激了多种土壤生态系统中初级生产者的生长和活性。 | Xu, Y. | PDF | N/A | Carbon monoxide exposure stimulates growth and activity of primary producers in diverse soil ecosystems | | 肽设计通过结合界面模拟 | Kong, X. | PDF | N/A | Peptide Design through Binding Interface Mimicry | | 海藻酸-ε聚赖氨酸核壳水凝胶珠作为一种有效、稳定且可扩展的微生物封装工具 | Amaro-Cruz, A. | PDF | N/A | Alginate-ϵPLL core-shell hydrogel beads as a tool for an effective, stable and scalable microbial encapsulation | | 重新审视CAR T细胞工程中对mRNA核苷修饰的需求 | Kahwaji, N. | PDF | N/A | Revisiting the need for mRNA nucleoside modification in CAR T cell engineering | | 零样本、大样本、主动样本——如何懒散地估计细胞汇合度 | Joas, M. J. | PDF | N/A | Zero-Shot, Big-Shot, Active-Shot - How to estimate cell confluence, lazily | | 离子化脂质纳米颗粒转染效率的缓冲特异性与体相转变 | Carucci, C. | PDF | N/A | Buffer specificity of ionizable lipid nanoparticle transfection efficiency and bulk phase transition | | 小分子控制的基因表达：设计针对定制核糖开关的药物样高亲和力小分子调节剂 | Hedwig, V. | PDF | N/A | Small molecule-controlled gene expression: Design of drug-like high affinity small molecule modulators of a custom-made riboswitch | | 全局转录组分析发现烟酰胺代谢在干扰素-γ和一氧化氮调控的反应中起关键作用。 | Chattopadhyay, A. | PDF | N/A | Global transcriptome analysis identifies nicotinamide metabolism to play key roles in IFN-gamma and nitric oxide modulated responses | | 以下是您提供的英文文本的中文翻译：

GC-MS分析与体外抗菌、抗生物膜和抗粘附活性：柽柳（Tamarix ericoides Rottl.）叶提取物对导管相关尿路感染病原体的作用

翻译说明：
- GC-MS Profiling：GC-MS分析，指通过气相色谱-质谱联用技术对样品成分进行分析。
- In vitro：体外实验，指在实验室条件下进行的非活体实验。
- Antibacterial：抗菌，指抑制或杀灭细菌的能力。
- Anti-Biofilm：抗生物膜，指抑制细菌形成生物膜的能力。
- Anti-adhesive：抗粘附，指抑制细菌粘附到表面的能力。
- Tamarix ericoides Rottl.：柽柳（学名），一种植物。
- Catheter-Associated Urinary Tract Infectious Agents：导管相关尿路感染病原体，指因使用导管而引发的尿路感染相关病原体。