BioRxiv 2025-01-24 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 在应对过氧化氢的适应性反应中,抗压能力与耐受性之间的权衡构成了其基础。 | Jacquel, B. | N/A | A trade-off between stress resistance and tolerance underlies the adaptive response to hydrogen peroxide | |
| 在选择PI3K驱动减毒的nef变体后,SIV特异性中和抗体的诱导 | Yamamoto, H. | N/A | SIV-specific neutralizing antibody induction following selection of a PI3K drive-attenuated nef variant | |
| 将这段翻译成中文是:使用CLEAN对测序数据进行定向去污染。 | Lataretu, M. | N/A | Targeted decontamination of sequencing data with CLEAN | |
| 与领域特定方法相比,惩罚回归利用来自混合细胞群体的RNA-seq数据改进了细胞类型特异性表达的估算。 | Lin, W.-Y. | N/A | Penalised regression improves imputation of cell-type specific expression using RNA-seq data from mixed cell populations compared to domain-specific methods | |
| QPPLab:一款普遍适用的软件包,用于检测、分析和可视化大规模脑活动的准周期性时空模式(QPPs)。 | Xu, N. | N/A | QPPLab: A generally applicable software package for detecting, analyzing, and visualizing large-scale quasiperiodic spatiotemporal patterns (QPPs) of brain activity | |
| 非线性状态下计算机模拟代谢动力学的扰动-响应分析:辅因子中的硬编码响应性与网络稀疏性 | Himeoka, Y. | N/A | Perturbation-response analysis of in silico metabolic dynamics in nonlinear regime: Hard-coded responsiveness in the cofactors and network sparsity | |
| 大型无脊椎动物的丰度和群落结构是否取决于位于城郊地区池塘的水质? | Hulot, F. D. | N/A | Do macroinvertebrate abundance and community structure depend on the quality of ponds located in peri-urban areas? | |
| 人类逐渐感受到对由他们行动引发的事件的主导权。 | Toma, M. | N/A | Humans progressively feel agency over events triggered before their actions | |
| scDiffEq:利用神经随机微分方程对单细胞动态进行漂移-扩散建模 | Vinyard, M. E. | N/A | scDiffEq: drift-diffusion modeling of single-cell dynamics with neural stochastic differential equations | |
| DORSSAA:基于稳定性/溶解度变化测定的药物-靶点相互作用组学资源 | Zangene, E. | N/A | DORSSAA: Drug-target interactOmics Resource based on Stability/Solubility Alteration Assay | |
| NEAR:氨基酸关系的神经嵌入 | Olson, D. R. | N/A | NEAR: Neural Embeddings for Amino acid Relationships | |
| BiaPy:生物图像上的易用深度学习 | Franco-Barranco, D. | N/A | BiaPy: Accessible deep learning on bioimages | |
| 运动依赖的听觉门控到顶叶皮层指导多感官决策 | Choi, I. | N/A | Locomotion-dependent auditory gating to the parietal cortex guides multisensory decisions | |
| 全球废水处理厂中的RNA病毒组揭示了生态洞察与人类健康影响 | Yuan, L. | N/A | Global RNA Virome in Wastewater Treatment Plants Reveals Ecological Insights and Human Health Implications | |
| 在代谢组学中弥合极性差异:串联质谱之间的跨电离模式化学相似性预测 | de Jonge, N. F. | N/A | Bridging polarities in metabolomics: Cross-ionization mode chemical similarity prediction between tandem mass spectra | |
| 将这段翻译成中文如下: |
遗传结构基础下的松树对真菌病原体Dothistroma septosporum的响应:以洛奇波尔松、杰克松及其杂交种为例
这段文字探讨了洛奇波尔松、杰克松及其杂交种对真菌病原体Dothistroma septosporum的响应背后的遗传结构。 | Lu, M. | PDF | N/A | Genetic architecture underlying response to the fungal pathogen Dothistroma septosporum in lodgepole pine, jack pine, and their hybrids | | 精细的运动数据揭示了濒危的百慕大海燕在水面觅食和夜间飞行的活动。 | Becciu, P. | PDF | N/A | Fine-scale movement data reveal surface foraging and nocturnal flight activity in the endangered Bermuda petrel | | 在句子生成过程中,一种与幅度无关的神经编码用于语言信息 | Morgan, A. M. | PDF | N/A | A magnitude-independent neural code for linguistic information during sentence production | | 偏离规范功能的情感情景记忆揭示了与不同精神疾病中情感症状相关的跨尺度神经多样性改变。 | Xiao, Y. | PDF | N/A | Deviations from normative functioning underlying emotional episodic memory revealed cross-scale neurodiverse alterations linked to affective symptoms in distinct psychiatric disorders | | 在北方森林中实现生态和经济上可持续的木材采伐水平——界定森林利用的安全操作空间 | Mönkkönen, M. | PDF | N/A | Ecologically and economically sustainable level of timber harvesting in boreal forests - defining the safe operating space for forest use | | 通过整合单细胞水平的研究揭示了牡蛎免疫细胞的多样性和功能特化 | De La Forest Divonne, S. | PDF | N/A | Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations | | 不完全的重组抑制导致了蝴蝶颜色图案超级基因中广泛的单倍型多样性。 | De-Kayne, R. | PDF | N/A | Incomplete recombination suppression fuels extensive haplotype diversity in a butterfly color pattern supergene | | 蜂蜜批量DNA宏基因组分析用于鉴定蜂蜜的生物成分并监测蜜蜂病原体 | Paluoja, P. | PDF | N/A | Honey bulk DNA metagenomic analysis to identify honey biological composition and monitor honey bee pathogens | | 迈向基于自然语言的全新蛋白质设计 | Dai, F. | PDF | N/A | Toward De Novo Protein Design from Natural Language | | 鞘氨醇-1-磷酸信号通路调节了穆勒胶质细胞转化为具有神经生成能力的、增殖性祖细胞样细胞的能力。 | Taylor, O. | PDF | N/A | Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells | | 硫化氢缺乏及其在心脏代谢性HFpEF中的治疗靶向:与GLP-1/胰高血糖素激动剂协同获益的证据
在这段翻译中,"Hydrogen Sulfide Deficiency" 被译为 "硫化氢缺乏","Therapeutic Targeting" 译为 "治疗靶向","Cardiometabolic HFpEF" 译为 "心脏代谢性HFpEF"(HFpEF指射血分数保留的心力衰竭),"Evidence for Synergistic Benefit with GLP-1/Glucagon Agonism" 译为 "与GLP-1/胰高血糖素激动剂协同获益的证据"。整体翻译保持了原文的专业性和准确性。 | Doiron, J. | PDF | N/A | Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF: Evidence for Synergistic Benefit with GLP-1/Glucagon Agonism | | α-D-甘露糖苷酶抑制剂(-)-Swainsonine的生物合成 | Liu, S. | PDF | N/A | Biosynthesis of the alpha-D-Mannosidase Inhibitor (-)-Swainsonine | | 小细胞肺癌的转移器官趋向性 | Krishnamurthy, M. | PDF | N/A | Metastatic organotropism in small cell lung cancer | | 高分辨率的黑皮质素-4受体深度突变扫描有助于药物发现中的靶点表征 | Howard, C. J. | PDF | N/A | High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery | | 产前压力、线粒体健康与孕周之间的关联:来自美国和土耳其两项妊娠研究的发现 | Huang, Q. | PDF | N/A | Associations between prenatal distress, mitochondrial health, and gestational age: findings from two pregnancy studies in the USA and Turkey | | 小分子激活TFEB通过促进溶酶体胞吐和生物发生缓解尼曼-匹克病C型 | Du, K. | PDF | N/A | Small-molecule Activation of TFEB Alleviates Niemann-Pick Disease Type C via Promoting Lysosomal Exocytosis and Biogenesis | | 特定细胞类型的驱动线靶向果蝇中央复合体及其在神经肽表达和睡眠调节研究中的应用 | Wolff, T. | PDF | N/A | Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation | | PAV-spotter:利用信号互相关识别目标捕获数据中的存在/缺失变异 | de Visser, M. C. | PDF | N/A | PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data | | 解码句子生成过程中的词汇:通过ECoG揭示的句法角色编码与结构依赖性动态 | Morgan, A. M. | PDF | N/A | Decoding words during sentence production: Syntactic role encoding and structure-dependent dynamics revealed by ECoG | | 利用大型语言模型增强基因集过度表达分析 | Zhu, J. | PDF | N/A | Enhancing Gene Set Overrepresentation Analysis with Large Language Models | | 在乳腺癌中,波形蛋白中的一个半胱氨酸残基调节长链非编码RNA XIST,以抑制上皮-间质转化和干细胞特性。 | Usman, S. | PDF | N/A | A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer | | 线粒体活性氧(ROS)和HIF-1α信号介导关键期可塑性 | Sobrid-Camean, D. | PDF | N/A | Mitochondrial ROS and HIF-1α signalling mediate critical period plasticity | | 双皮质素域蛋白ZYG-8通过微管硬化促进秀丽隐杆线虫合子分裂过程中的纺锤体定向 | Cueff, L. | PDF | N/A | Microtubule stiffening by doublecortin-domain protein ZYG-8 contributes to spindle orientation during C. elegans zygote division | | 使用机器学习预测小分子的抗菌类别特异性 | Gadiya, Y. | PDF | N/A | Predicting antimicrobial class specificity of small molecules using machine learning | | 斑马鱼触觉感觉轴突的直径在体内是动态变化的。 | Ching, K. | PDF | N/A | Caliber of zebrafish touch-sensory axons is dynamic in vivo | | 在单细胞分辨率下绘制细胞-细胞融合图谱 | Gardner, A. L. | PDF | N/A | Mapping cell-cell fusion at single-cell resolution | | 适应过程塑造了小鼠初级视觉皮层(V1)中的表征几何结构,以高效地编码环境信息。 | Dipoppa, M. | PDF | N/A | Adaptation shapes the representational geometry in mouse V1 to efficiently encode the environment | | 机器学习预测超越单个mRNA作为单细胞蛋白质表达的代表 | Fisher, J. | PDF | N/A | Machine Learning Predictions Surpass Individual mRNAs as a Proxy of Single-cell Protein Expression | | 收集、检测和处理纵向光照数据中的非佩戴间隔 | Guidolin, C. | PDF | N/A | Collecting, detecting and handling non-wear intervals in longitudinal light exposure data | | 空间和特征依赖的皮层回路模型中的扰动响应的精确线性理论 | Chau, H. Y. | PDF | N/A | Exact linear theory of perturbation response in a space- and feature-dependent cortical circuit model | | 我们能否从群体活动的频谱中推断兴奋-抑制平衡? | Chakravarty, K. | PDF | N/A | Can we infer excitation-inhibition balance from the spectrum of population activity? | | 一种细菌间的半胱氨酸蛋白酶毒素通过靶向II型DNA拓扑异构酶GyrB和ParE来抑制细胞生长 | Song, P.-Y. | PDF | N/A | An Interbacterial Cysteine Protease Toxin Inhibits Cell Growth by Targeting Type II DNA Topoisomerases GyrB and ParE | | T细胞衍生的IFN-γ抑制T滤泡辅助细胞分化和抗体反应 | Sala, E. | PDF | N/A | T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses | | Mettl15-Mettl17调控从前早期到前晚期线粒体核糖体的转变 | Zgadzay, Y. | PDF | N/A | Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome | | 瑞士和马来西亚的生理相关光照和光照行为 | Biller, A. | PDF | N/A | Physiologically-relevant light exposure and light behaviour in Switzerland and Malaysia | | 通过凝视相关消息暴露实现记忆植入:利用虚拟现实研究媒体影响 | Cho, H. J. | PDF | N/A | Memory Inception through Gaze-Contingent Message Exposure: Using Virtual Reality to Study Media Influence | | grepq:一个用Rust编写的应用程序,能够通过将序列与一组正则表达式进行匹配来快速过滤FASTQ文件。 | Crosbie, N. D. | PDF | N/A | grepq: A Rust application that quickly filters FASTQ files by matching sequences to a set of regular expressions | | 潮间带甲壳动物Eurydice pulchra和Parhyale hawaiensis大脑中时钟基因的表达追踪了每日和潮汐时间 | Oliphant, A. | PDF | N/A | Expression of clock genes tracks daily and tidal time in brains of intertidal crustaceans Eurydice pulchra and Parhyale hawaiensis | | 追踪从婴儿粪便中分离的链球菌菌株在人体各部位的分布情况,揭示了肠道特异性与粘附素之间的联系。 | Ormaasen, I. | PDF | N/A | Tracing of streptococcal strains from infant stool across human body sites links gut specificity to adhesins | | 柠檬酸的胞质运输保护了营养匮乏的胰腺癌免受铁死亡的影响。 | Kneebone, A. | PDF | N/A | Cytosolic transport of citrate protects nutrient-austere pancreatic cancer from ferroptosis | | 高产生物生产无病毒病毒样P4-EKORhE多重溶菌转导颗粒作为抗菌基因治疗剂 | Ramirez-Garcia, R. | PDF | N/A | High-yield bioproduction of virus-free virus-like P4-EKORhE multi-lysin transducing particles as an antimicrobial gene therapeutic | | 单个背侧迷走神经复合体回路介导了GLP1R激动剂的厌恶和厌食反应。 | Yacawych, W. T. | PDF | N/A | A single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists | | 人类母乳寡糖通过梭菌属物种的代谢抑制炎症和病原体生长 | Chapman, J. A. | PDF | N/A | Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth | | 人类母乳低聚糖通过梭菌属物种代谢,抑制炎症和病原体生长 | Chapman, J. A. | PDF | N/A | Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth | | 测量空间排序的强度 | Goel, N. | PDF | N/A | Measuring the Strength of Spatial Sorting | | 使用pyCERR和癌症基因组云进行医学图像分析的人工智能应用 | Apte, A. | PDF | N/A | Artificial Intelligence Apps for Medical Image Analysis using pyCERR and Cancer Genomics Cloud | | 氯化物细胞内通道(CLIC)蛋白在S1P诱导的Rac1激活中的功能需要C末端在膜上的定位,而不需要硫醇转移酶或离子通道活性。 | Mao, D. Y. | PDF | N/A | Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities. | | 使用荧光显微镜进行便捷且准确的细胞计数分析 | Foyt, D. | PDF | N/A | Accessible and accurate cytometry analysis using fluorescence microscopes | | ADAMTS10和ADAMTS17联合失活会加剧骨骼缩短和皮肤表型。 | Taye, N. | PDF | N/A | Combined ADAMTS10 and ADAMTS17 inactivation exacerbates bone shortening and skin phenotypes | | Cell-APP: 一种通用的微观细胞注释、分割和分类方法 | Virdi, A. J. | PDF | N/A | Cell-APP: A generalizable method for microscopic cell annotation, segmentation, and classification | | 由防御信号或伤害引发的细胞质钙离子局部行波通过不同的机制进行传播。 | Zhang, W. | PDF | N/A | Local traveling waves of cytosolic calcium elicited by defense signals or wounding are propagated by distinct mechanisms | | 线粒体mRNA的超分辨率显微镜成像 | Stoldt, S. | PDF | N/A | Super-resolution microscopy of mitochondrial mRNAs | | 从使用延迟嵌入分析的未标记活细胞光显微镜数据中推断分子报告物的单细胞动态 | Singh, J. | PDF | N/A | Inferring single-cell dynamics of a molecular reporter from unlabeled live-cell light microscopy data analyzed with delay embedding | | Connexin50半通道被CO2激活:对晶状体生理学的意义 | Lovatt, A. | PDF | N/A | Connexin50 hemichannels are opened by CO2: implications for lens physiology | | 基因效应从调控因子到程序再到性状的因果建模:遗传关联与Perturb-seq的整合 | Ota, M. | PDF | N/A | Causal modeling of gene effects from regulators to programs to traits: integration of genetic associations and Perturb-seq | | 厌氧消化池中的生物强化:系统性综述 | Alipoursarbani, M. | PDF | N/A | Bioaugmentation in anaerobic digesters: A systematic review | | 基于单链抗体的AID2系统,用于条件性降解GFP标记及未标记蛋白 | Islam, M. | PDF | N/A | A single-chain antibody-based AID2 system for conditional degradation of GFP-tagged and untagged proteins | | X-Pro:一个基于网络的工具,用于蛋白质结构上点突变的结构分析。 | Vishwakarma, A. T. | PDF | N/A | X-Pro: A Web-based tool for structural analysis of point mutations on protein structures. | | 单细胞编辑检测与识别工具(scEDIT):用于高效且经济的CRISPR编辑细胞单细胞分析的计算工作流程 | Suryawanshi, G. W. | PDF | N/A | Single cell Edit Detection and Identification Tool (scEDIT): computational workflow for efficient and economical single cell analysis of CRISPR edited cells | | NRGSuite-Qt: 一个PyMOL插件,用于高通量虚拟筛选、分子对接、正常模式分析、分子相互作用研究以及结合位点相似性检测。 | Galdino, G. T. | PDF | N/A | NRGSuite-Qt: A PyMOL plugin for high-throughput virtual screening, molecular docking, normal-mode analysis, the study of molecular interactions and the detection of binding-site similarities | | SARS-CoV-2 N蛋白的一个二聚体可以与多个单链和茎环RNA片段结合。 | Kaneda, N. | PDF | N/A | A single dimer of the SARS-CoV-2 N protein can associate with multiple fragments of single-stranded and stem-loop RNAs | | 通过2.2-2.3埃低温电子显微镜观察RNA中的复杂水网络可视化 | Kretsch, R. C. | PDF | N/A | Complex Water Networks Visualized through 2.2-2.3 Angstrom Cryogenic Electron Microscopy of RNA | | 伤害感受器TRPM3的趋同激动剂和热激活 | Du, J. | PDF | N/A | Convergent Agonist and Heat Activation of Nociceptor TRPM3 | | fCUT&Tag-seq:一种优化的CUT&Tag方法,用于在模型和植物病原真菌中进行高分辨率组蛋白修饰和染色质结合蛋白分析 | Wang, H. | PDF | N/A | fCUT&Tag-seq: An Optimized CUT&Tag-based Method for High-Resolution Histone Modification and Chromatin-Binding Protein Profiling in both Model and Plant Pathogenic Fungi | | DUX4刺激的基因定义了人类滋养层细胞对疱疹病毒的抗病毒反应 | Hatterschide, J. | PDF | N/A | DUX4-stimulated genes define the antiviral response to herpesviruses in human trophoblasts | | 人类面部皮肤的微生物群落与其他类人猿相比具有独特性。 | Degregori, S. | PDF | N/A | The microbiome of the human facial skin is unique compared to that of other hominids | | 棕榈油酸保护神经元免受寨卡病毒感染引起的内质网应激和细胞凋亡 | Krishnamoorthy, C. | PDF | N/A | Palmitoleate Protects against Zika virus infection-induced Endoplasmic Reticulum Stress and Apoptosis in Neurons | | pOXA-48质粒在大肠杆菌中维持和传播的遗传决定因素 | Baffert, Y. | PDF | N/A | Genetic Determinants of pOXA-48 Plasmid Maintenance and Propagation in Escherichia coli | | 当依赖型突变体从其独立祖先中分离出来时,微生物的交叉喂养关系会趋于稳定。 | Schakel, O. F. | PDF | N/A | Microbial cross-feeding is stabilized when a dependent mutant is segregated from its independent ancestor | | 加纳南部沃尔特湖沿岸岛屿社区中的疟疾媒介多样性、传播和杀虫剂抗性研究。 | Ebuako, A. A. | PDF | N/A | Malaria vector diversity, transmission, and insecticide resistance, in island communities along the Volta Lake in southern Ghana. | | DMEM和EMEM是适合的替代培养基,可用于模拟宿主环境,并通过体外工具扩展钩端螺旋体致病机制的研究。 | Garcia, L. | PDF | N/A | DMEM and EMEM are suitable surrogate media to mimic host environment and expand leptospiral pathogenesis studies using in vitro tools | | 多基因病毒因素使得非洲寨卡病毒能够高效通过蚊媒传播。 | Torii, S. | PDF | N/A | Polygenic viral factors enable efficient mosquito-borne transmission of African Zika virus | | 历史塑造了对抗生素时代前后鲍曼不动杆菌菌株对替加环素的调控和进化反应 | Rokes, A. S. | PDF | N/A | History shapes regulatory and evolutionary responses to tigecycline in strains of Acinetobacter baumannii from the pre- and post-antibiotic eras | | 历史塑造了对抗生素时代前后鲍曼不动杆菌菌株对替加环素的调控和进化反应 | Rokes, A. B. | PDF | N/A | History shapes regulatory and evolutionary responses to tigecycline in strains of Acinetobacter baumannii from the pre- and post-antibiotic eras | | 南非褐蝗(Locustana pardalina)携带有对氟康唑耐药的Candidozyma(Candida)auris(分支III)。 | Ogundeji, A. | PDF | N/A | South African brown locusts, Locustana pardalina, hosts fluconazole resistant Candidozyma (Candida) auris (Clade III) | | 旧世界甲病毒利用不同的机制感染脑微血管内皮细胞以实现神经侵袭 | Alvarez, P. A. | PDF | N/A | Old World alphaviruses use distinct mechanisms to infect brain microvascular endothelial cells for neuroinvasion | | 米卡芬净对人细胞系中翼手蝙蝠正呼肠孤病毒感染的作用机制 | Bubphasook, W. | PDF | N/A | The mechanism of Micafungin action to Pteropine orthoreovirus infection in human cell line | | 2,4-二烯酰辅酶A还原酶在复杂脂肪酸混合物降解中的关键作用 | Schiaffi, V. | PDF | N/A | The essential role of 2,4-dienoyl-CoA reductase for degradation of complex fatty acid mixtures | | 揭示细菌领域中起始元件和启动子结构 | Kuo, S.-T. | PDF | N/A | Unravel the start element and promoter architecture across the domain Bacteria | | 评估抗生素在人类胃肠道微生物群的临床前模型中的影响 | Auchtung, T. A. | PDF | N/A | Evaluating effects of antibiotics across preclinical models of the human gastrointestinal microbiota | | HIV-1 亚型 C LTR Sp1IIIT5A 突变体增强了转录活性和 Sp1 结合亲和力 | Msthali, N. | PDF | N/A | HIV-1 subtype C LTR Sp1IIIT5A mutant enhances transcription activity and Sp1 binding affinity | | 加州Calasterella的真菌微生物组主要由宿主菌体的遗传特性决定。 | Gonzalez-Ramirez, I. | PDF | N/A | The microbiome of Calasterella californica is shaped mostly by the genetics of the host thalli | | 克隆干扰和不断变化的选择压力塑造了SARS-CoV-2从数百种抗体中的逃逸 | Haddox, H. K. | PDF | N/A | Clonal interference and changing selective pressures shape the escape of SARS-CoV-2 from hundreds of antibodies | | 一种具有共识刺突蛋白的反式扩增mRNA疫苗能够引发针对多种SARS-CoV-2变体的广泛交叉中和抗体反应。 | Gontu, A. | PDF | N/A | A trans-amplifying mRNA vaccine with consensus spike elicits broadly cross-neutralizing antibody response against multiple SARS-CoV-2 variants | | 在非洲不同人群中,肠道寄生虫感染与肠道微生物组多样性之间存在相关性。 | Ngwese, M. M. | PDF | N/A | Infection with gut parasites correlates with gut microbiome diversity across human populations in Africa | | N6-甲基腺苷RNA甲基化对组蛋白H1亚型的差异调控。 | Garcia-Gomis, D. | PDF | N/A | Differential regulation of histone H1 subtypes by N6-methyladenosine RNA methylation. | | ACTN3 R577X基因多态性的R等位基因与印度精英拳击手状态相关 | Grover, V. K. | PDF | N/A | R allele of ACTN3 R577X gene polymorphism is associated with Elite Indian Boxer Status | | 组氨酸激酶VraS通过与糖肽类和β-内酰胺类抗生素的直接相互作用,调控金黄色葡萄球菌的细胞壁应激反应。 | Antinori, M. B. | PDF | N/A | The histidine kinase VraS orchestrates the cell-wall stress response in Staphylococcus aureus via its direct interaction with glycopeptides and β-lactams | | 使用全质粒CRISPRi筛选剖析临床肠杆菌中pOXA-48的适应性效应 | Calvo-Villamanan, A. | PDF | N/A | Dissecting pOXA-48 fitness effects in clinical enterobacteria using plasmid-wide CRISPRi screens | | 通过对Paenibacilli属中次级代谢产物生产基因簇的广泛探索,揭示其生物合成潜力 | Song, L. | PDF | N/A | Unlocking the biosynthetic potential of Paenibacilli through a genus-wide exploration of gene clusters for secondary metabolite production | | 大规模基因组分析揭示了大肠杆菌中VI型分泌系统的分布与多样性 | Nesporova, K. | PDF | N/A | Large-scale genomic analysis reveals the distribution and diversity of Type VI Secretion Systems in Escherichia coli | | 以下是这段英文的中文翻译:
BvlzGluc的表征:一种来自贝莱斯芽孢杆菌的新型抗真菌β-葡聚糖酶,具有潜在的农业和工业应用价值
翻译说明: - Characterization 翻译为“表征”,指对物质或生物分子的特性进行详细描述和分析。 - BvlzGluc 是文章中提到的一种酶的名称,通常保留原文不翻译。 - Novel Antifungal beta-Glucanase 翻译为“新型抗真菌β-葡聚糖酶”,其中“β-葡聚糖酶”是一种能够分解β-葡聚糖的酶。 - Bacillus velezensis 翻译为“贝莱斯芽孢杆菌”,是一种细菌的名称。 - Potential Agricultural and Industrial Applications 翻译为“潜在的农业和工业应用价值”,表示这种酶在农业和工业领域可能有广泛的应用前景。
希望这个翻译对你有帮助!如果需要进一步调整或补充,请告诉我。 | VELA-CORCIA, D. | PDF | N/A | Characterization of BvlzGluc, a Novel Antifungal beta-Glucanase from Bacillus velezensis, with Potential Agricultural and Industrial Applications | | 利用依赖MBNL的选择性剪接盒式外显子来控制强直性肌营养不良症中的基因治疗 | Carrell, S. | PDF | N/A | Co-opting MBNL-dependent alternative splicing cassette exons to control gene therapy in myotonic dystrophy | | 解析D29LysA和DS6ALysA噬菌体内溶酶催化域对分枝杆菌细胞壁水解的分子基础 | Ceballos-Zuniga, F. | PDF | N/A | Dissecting the molecular basis underlying mycobacterial cell-wall hydrolysis by the catalytic domains of D29LysA and DS6ALysA phage endolysins | | 通过构建永生化细胞系的微流体共培养体系,揭示了同时形成图案化、血管化和干细胞来源脂肪组织的稳健设计原则。 | Murphy, A. R. | PDF | N/A | Fabricating microfluidic co-cultures of immortalised cell lines uncovers robust design principles for the simultaneous formation of patterned, vascularised, and stem cell-derived adipose tissue. | | 我是谁?干细胞移植后生殖系基因检测的最佳组织选择 | Mertens, M. | PDF | N/A | Who am I? Optimal Tissue for Germline Genetic Testing Post-Stem Cell Transplantation | | 剪切应力通过下调长链非编码RNA MALAT1抑制脂肪细胞分化。 | Wang, S. | PDF | N/A | Shear stress inhibits adipocyte differentiation via downregulating lncRNA MALAT1 | | 基于k-mer的最大似然方法用于估计读取片段与基因组之间的距离,从而实现全基因组范围的系统发育定位。 | Sapci, A. O. B. | PDF | N/A | A k-mer-based maximum likelihood method for estimating distances of reads to genomes enables genome-wide phylogenetic placement. | | 翼铰链动力学对扑翼昆虫的扑动幅度影响:一种频率响应方法 | Casey, C. | PDF | N/A | Wing Hinge Dynamics Influence Stroke Amplitudes in Flapping Wing Insects: A Frequency Response Approach | | 老化引导KRAS驱动的肺腺癌的差异进化 | Lazure, F. | PDF | N/A | Aging directs the differential evolution of KRAS-driven lung adenocarcinoma | | 三维癌细胞球体的形态和活力评估的深度学习流程 | Mali, A. K. | PDF | N/A | A Deep Learning Pipeline for Morphological and Viability Assessment of 3D Cancer Cell Spheroids | | 比较小鼠、狗和人类毛囊-T细胞相互作用的空间转录组学揭示了原发性瘢痕性脱发的保守驱动因素 | Yildiz-Altay, U. | PDF | N/A | Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopecia | | 利用GP1 PPSPX基序工程化微藻细胞壁锚定蛋白,并通过内含肽介导的融合进行释放。 | Kang, K. | PDF | N/A | Engineering microalgal cell wall-anchored proteins using GP1 PPSPX motifs and releasing with intein-mediated fusion | | 以下是翻译:
与梨衰退病相关的Candidatus Phytoplasma pyri的首个基因组资源
翻译说明: 1. "First genomic resource" 翻译为 "首个基因组资源" 2. "Candidatus Phytoplasma pyri" 是微生物学名,保留原文 3. "associated to pear decline" 翻译为 "与梨衰退病相关的" 4. 按照中文表达习惯,将关联词"associated to"放在前面,形成"与...相关的"结构
这个标题表明这是首次对引起梨衰退病的植原体(Candidatus Phytoplasma pyri)进行基因组研究并建立相关资源。 | Alessio, F. I. | PDF | N/A | First genomic resource of Candidatus Phytoplasma pyri associated to pear decline | | 脂质纳米颗粒表面形成的蛋白冠会降低mRNA货物的递送效率。 | Voke, E. | PDF | N/A | Protein corona formed on lipid nanoparticles compromises delivery efficiency of mRNA cargo | | 开发具有可诱导神经酰胺耗竭的人类皮肤等效物,用于体外模拟脂质缺乏 | Dina, D. O. | PDF | N/A | Development of human skin equivalents with inducible ceramide depletion for in vitro modelling of lipid deficiency | | 指标的重要性:为何我们需要在单细胞基准测试中停止使用轮廓系数 | Rautenstrauch, P. | PDF | N/A | Metrics Matter: Why We Need to Stop Using Silhouette in Single-Cell Benchmarking | | 代谢程序的表观遗传失调介导了脂肪肉瘤细胞的可塑性 | Pimenta, E. M. | PDF | N/A | Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity | | FOXO和Tribbles蛋白的联合表达预测胶质瘤患者的生存率 | Santos, B. F. | PDF | N/A | Combined expression of FOXO and Tribbles proteins predicts survival of glioma patients | | 先天免疫记忆具有刺激特异性 | O'Farrell, A. | PDF | N/A | Innate Immune Memory is Stimulus Specific | | 修补细胞核:PMLII在核膜破裂修复中的新角色 | Janssen, A. F. | PDF | N/A | Patching up the nucleus: a novel role for PMLII in nuclear envelope rupture repair | | 基于饮食凝胶的口服药物递送系统,用于小分子的控制剂量,以实现小鼠小胶质细胞的耗竭和可诱导的Cre重组。 | Jovanovic, J. | PDF | N/A | Diet gel-based oral drug delivery system for controlled dosing of small molecules for microglia depletion and inducible Cre recombination in mice | | Glyco-PAINT-APP:免疫细胞-凝集素结合的亚细胞分析使得糖结合参数与受体生物学相关联 | Steuten, K. | PDF | N/A | Glyco-PAINT-APP: Subcellular analysis of immune cell-lectin binding enables correlation of glycan binding parameters to receptor biology | | IFN-γ诱导的肠上皮细胞特异性程序性细胞死亡:PANoptosis及其在克罗恩病中的调控
这段文字主要讨论了IFN-γ(干扰素-γ)在特定类型的肠上皮细胞中引发的程序性细胞死亡过程,称为PANoptosis,并探讨了这一过程在克罗恩病中的调节机制。 | Lee, C. | PDF | N/A | IFN-gamma-Induced Intestinal Epithelial Cell-Type-Specific Programmed Cell Death: PANoptosis and Its Modulation in Crohn's Disease | | 显微镜引导的空间蛋白质组学揭示了线粒体-脂滴界面上的新型蛋白质及其在脂质代谢中的作用 | Lin, Y.-M. | PDF | N/A | Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism | | 生成建模用于RNA剪接预测与设计 | Wu, D. | PDF | N/A | Generative modeling for RNA splicing predictions and design | | 性别特异性转录组相似性网络阐明了共病关系 | Sanchez-Valle, J. | PDF | N/A | Sex-specific transcriptome similarity networks elucidate comorbidity relationships | | 性激素结合球蛋白控制人类腹部皮下脂肪细胞的性别特异性脂解活性 | Abildgaard, J. | PDF | N/A | Sex Hormone Binding Globulin Controls Gender Specific Lipolytic Activity in Human Abdominal Subcutaneous Adipocytes | | 线粒体ATP敏感性钾离子通道(MitoKATP)调控棕色脂肪细胞的分化与代谢 | Pereira, O. R. | PDF | N/A | Mitochondrial ATP-Sensitive K+ Channels (MitoKATP) Regulate Brown Adipocyte Differentiation and Metabolism | | 范可尼贫血蛋白的丧失导致细胞依赖于溶酶体胞吐作用。 | Fu, B. X. H. X. H. | PDF | N/A | Loss of Fanconi anemia proteins causes a reliance on lysosomal exocytosis | | 染色体的有益基因捕获驱动质粒走向生态冗余 | MacLean, C. | PDF | N/A | Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy | | 细胞培养的PDMS血管模型,用于植入设备的放置。 | Okuno, T. | PDF | N/A | Cell-cultured PDMS vascular model to allow placement of implant devices | | 多组而非单一受体肌腱转移在侧捏握力中产生良好导向的拇指尖力量:一项模拟研究及其在四肢瘫痪后改善握力恢复中的应用 | Garcia, O. | PDF | N/A | Multiple, not single, recipient muscle tendon transfers produce well-directed thumb-tip forces in lateral pinch grasp: a simulation study with application to restoration of improved grasp after tetraplegia | | 本地植物叶际真菌对入侵植物紫茎泽兰幼苗的致死效应 | Zeng, Z.-Y. | PDF | N/A | Lethal effects of phyllosphere fungi associated with local plants on invasive plant Ageratina adenophora seedlings | | 从单细胞RNA测序中检测细胞类型特异性表达数量性状位点(eQTL)揭示了人类胰岛中的转录后调控机制 | de Winter, T. J. | PDF | N/A | Cell type-specific eQTL detection from single-cell RNA-seq reveals post-transcriptional regulatory mechanisms in human islets | | 使用PRISM重新审视癌症微生物组 | Ghaddar, B. C. | PDF | N/A | Revisiting the cancer microbiome using PRISM | | 请将以下内容翻译成中文:ERGA-BGE Androsace saussurei Dentant, Lavergne, F. C. Boucher & S. Ibanez 的基因组,这是一种最近被描述的来自欧洲屋顶的植物。 | Lavergne, S. | PDF | N/A | ERGA-BGE genome of Androsace saussurei Dentant, Lavergne, F. C. Boucher & S. Ibanez, a recently described plant from the rooftops of Europe | | 单细胞差异去垢剂分馏法用于检测细胞角蛋白8的蛋白质形式 | Khartchenko, A. F. | PDF | N/A | Single-cell differential detergent fractionation for detection of cytokeratin 8 proteoforms | | 从背景到信号:基于甲基化依赖性测序的无细胞DNA同时获取拷贝数 | Hazelaar, D. M. | PDF | N/A | From Background to Signal: Simultaneously derived Copy Numbers from Methylation-Dependent Sequencing cell-free DNA | | 通过对巴基斯坦复杂环境样本中炭疽杆菌的基因组重建,实现了高通量鉴定和谱系归属。 | Podowski, J. C. | PDF | N/A | Genomic reconstruction of Bacillus anthracis from complex environmental samples enables high throughput identification and lineage assignment in Pakistan | | TransHLA: 用于HLA呈递表位检测的混合Transformer模型
TransHLA是一种结合了Transformer架构的混合模型,专门用于检测由人类白细胞抗原(HLA)呈递的表位。表位是免疫系统中能够被识别并引发免疫反应的关键部分,而HLA分子在将这些表位呈递给免疫细胞的过程中起着至关重要的作用。TransHLA模型通过整合Transformer的强大序列建模能力,能够更准确地预测哪些肽段会被HLA分子呈递,从而为疫苗设计和免疫治疗提供重要支持。 | LU, T. | PDF | N/A | TransHLA: A Hybrid Transformer Model for HLA-Presented Epitope Detection | | 基于有用性准则的跨群体杂交策略优化,考虑群体间不同遗传效应 | Kinoshita, S. | PDF | N/A | Optimization of crossing strategy based on the usefulness criterion in inter-population crosses considering different genetic effects among populations | | 脂质生成母体通过母乳介导的微生物转移改变后代肠道微生物群的发育 | Abdulrahim, U. | PDF | N/A | Lipogenic Mothers Alter Offspring Gut Microbiome Development via Breastmilk-Mediated Microbial Transfer | | 基于蛋白质语言模型注意力分析的多样化功能预测自动定义蛋白质词汇 | Chen, H. | PDF | N/A | Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model | | 利用迁移学习在斑马鱼图像分析中实现高精度表型筛选 | Jayaraman, V. U. | PDF | N/A | LEVERAGING TRANSFER LEARNING FOR HIGH-ACCURACY PHENOTYPIC SCREENING IN ZEBRAFISH IMAGE ANALYSIS | | WASTER:基于低覆盖度短读长的实用从头系统基因组学 | Zhang, C. | PDF | N/A | WASTER: Practical de novo phylogenomics from low-coverage short reads | | ResolVI - 解决空间转录组学中的噪音和偏差问题 | Ergen, C. | PDF | N/A | ResolVI - addressing noise and bias in spatial transcriptomics | | ProtRAP-LM:通过蛋白质语言模型嵌入实现快速准确的蛋白质相对可及性预测及膜蛋白筛选 | Wang, L. | PDF | N/A | ProtRAP-LM: Fast and accurate protein relative accessibility prediction and membrane protein screening through protein language model embeddings | | 表观遗传时钟与炎症衰老:忽视细胞类型异质性带来的陷阱 | Guo, X. | PDF | N/A | Epigenetic clocks and inflammaging: pitfalls caused by ignoring cell-type heterogeneity | | 深度建模功能增益突变对雄激素受体的影响 | You, J. | PDF | N/A | Deep Modeling of Gain of Function Mutations on Androgen Receptor | | 可调谐荧光DNA探针实现快速高分辨率单分子荧光成像 | Kummerlin, M. | PDF | N/A | Tunable fluorogenic DNA probes drive fast and high-resolution single-molecule fluorescence imaging | | 通过元动力学模拟和马尔可夫状态模型揭示G蛋白偶联受体构象动力学 | Roessner, R. A. | PDF | N/A | Unveiling G-Protein-Coupled Receptor Conformational Dynamics via Metadynamics Simulations and Markov State Models | | 乳腺癌中的DNA甲基化模式,与同侧和对侧乳腺的配对良性组织及健康对照组的比较。 | Dennis, S. R. | PDF | N/A | DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls. | | NF1基因疗法在丛状神经纤维瘤小鼠模型中的原理验证 | Bostanthirige, D. H. | PDF | N/A | Proof-of-principle of NF1 Gene Therapy in plexiform neurofibroma mice models | | 异质多细胞基质细胞融入无支架的三维上皮癌细胞培养中,以驱动侵袭。 | Ortiz, E. | PDF | N/A | Hetero-multicellular stromal cells incorporate into scaffold-free 3D cultures of epithelial cancer cells to drive invasion | | 高胆固醇会增加骨髓瘤的肿瘤负担,并促进对硼替佐米的耐药性。 | Gamez, B. | PDF | N/A | High cholesterol increases myeloma tumour burden and promotes resistance to bortezomib | | 在3D水凝胶中进行的可药物基因组CRISPRi筛选揭示了侵袭性胶质母细胞瘤细胞中皮层驱动肌动蛋白重塑的调控因子 | Hu, M. | PDF | N/A | Druggable genome CRISPRi screen in 3D hydrogels reveals regulators of cortactin-driven actin remodeling in invading glioblastoma cells | | 早期蛋白酶体基因下调与蛋白酶体功能受损是阿尔茨海默病中蛋白质稳态失败的基础 | Myeku, N. | PDF | N/A | Early Proteasome Gene Downregulation And Impaired Proteasomes Function Underlie Proteostasis Failure In Alzheimer's Disease | | 阿米奥达隆毒性的脂质组景观:一项以脂质为中心的体内多组学研究
这段翻译将英文标题“The Lipidome Landscape of Amiodarone Toxicity: An in vivo Lipid-centric Multi-Omics Study”转换为中文,保留了原文的学术性和专业性,同时确保了表达的准确性和流畅性。 | Thu, N. Q. | PDF | N/A | The Lipidome Landscape of Amiodarone Toxicity: An in vivo Lipid-centric Multi-Omics Study | | 重复给予自由进食的大鼠巴氯芬是否会通过激活交感神经系统刺激棕色脂肪代谢来减少体重? | Ebenezer, I. S. | PDF | N/A | Does repeated administration of baclofen in free feeding rats reduce body weight by stimulating brown fat metabolism through activation of the sympathetic nervous system? | | 输注条件和麻醉对小鼠脑脊液示踪剂动力学的影响 | Zhu, Y. | PDF | N/A | Impact of infusion conditions and anesthesia on CSF tracer dynamics in mouse brain | | 紊乱的1-磷酸鞘氨醇稳态驱动1-磷酸鞘氨醇裂解酶缺乏综合征(SPLIS)中的肾毒性 | Majcher, A. | PDF | N/A | Disrupted Sphingosine-1-Phosphate Homeostasis Drives Nephrotoxicity in Sphingosine-1-Phosphate Lyase Insufficiency Syndrome (SPLIS) | | 在次最大强度骑行过程中,由于忽略了负肌肉功率,机械效率被低估了。 | Vos, R. T. | PDF | N/A | Mechanical efficiency during sub-maximal cycling is underestimated because negative muscular power is ignored | | 母乳中的细菌在婴儿配方奶粉中形成了功能不同的合成群落,这些群落对新生迷你猪仔的肠道生理和微生物群产生了不同的影响。 | Le Bras, C. | PDF | N/A | Human milk bacteria assembled into functionally distinct synthetic communities in infant formula differently affect intestinal physiology and microbiota in neonatal mini-piglets | | 利用图像驱动的机器学习模型提升树种萌发预测能力。 | Barreiro, P. G. | PDF | N/A | Enhancing tree seed germination prediction with image-driven machine learning models. | | 评估产量可塑性对玉米杂交种表现的影响 | Davis, J. M. | PDF | N/A | Assessing the impact of yield plasticity on hybrid performance in maize | | 保卫细胞的光呼吸对拟南芥的光合作用、生长和气孔行为有重大影响。 | Sun, H. | PDF | N/A | Guard cell photorespiration has a major impact on photosynthesis, growth and stomatal behavior in Arabidopsis | | 凝缩素II在拟南芥中有效介导染色单体分离和对基因毒性胁迫的抵抗 | Vladejic, J. | PDF | N/A | Condensin II mediates efficient chromatid resolution and resistance to genotoxic stress in Arabidopsis | | 在蓝藻Synechococcus elongatus PCC 7942中,一种进化上保守的多重应激感应组氨酸激酶NblS与光系统II蛋白相关联,并对其氧化还原状态作出响应。 | Tsurumaki, T. | PDF | N/A | An Evolutionary Conserved Multi-Stress Sensory Histidine Kinase NblS Associates With Photosystem II Proteins And Responds To Its Redox Status In The Cyanobacterium Synechococcus elongatus PCC 7942 | | Schaffer联合输入调节CA1空间表征的稳定性 | Rais, C. | PDF | N/A | Schaffer commissural inputs regulate the stability of CA1 spatial representation | | 神经类固醇的多重作用 | Kumar, A. | PDF | N/A | Multifaceted Actions of Neurosteroids | | 阻断mTOR通路通过纠正人源化小鼠中CD89和CD71的功能障碍来改善IgA肾病。 | Cambier, A. | PDF | N/A | Blockade of mTOR ameliorates IgA Nephropathy by correcting CD89 and CD71 dysfunctions in humanized mice | | GPVI-血小板-中性粒细胞-NET轴驱动系统性硬化症 | Darbousset, R. | PDF | N/A | A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis | | 以下是这段英文的中文翻译:
淡水海绵Ephydatia muelleri在其分布范围内的基因组连通性和适应信号
翻译解释: - "Genomic connectivity" 翻译为 "基因组连通性",指的是不同种群之间基因交流的程度。 - "adaptation signals" 翻译为 "适应信号",指的是基因组中与适应性进化相关的特征或标记。 - "freshwater sponge" 翻译为 "淡水海绵",是一种生活在淡水环境中的海绵动物。 - "Ephydatia muelleri" 是这种海绵的学名,通常不翻译,直接使用拉丁名。 - "across its distribution" 翻译为 "在其分布范围内",指的是该物种的整个地理分布区域。
整个翻译的意思是:研究淡水海绵Ephydatia muelleri在其整个分布范围内的基因组连通性和适应性进化的信号。 | Cassidy, R. | PDF | N/A | Genomic connectivity and adaptation signals of the freshwater sponge Ephydatia muelleri across its distribution | | 附肢测量仪:一种用于同时进行果蝇腿和翅膀高通量形态测量的系统 | Rossoni, D. M. | PDF | N/A | Appendometer: A system for simultaneous, high-throughput morphometry of Drosophila legs and wings | | 组蛋白甲基转移酶SetDB1在其组蛋白模拟基序上的自动甲基化确保了异染色质的扩散和维持。 | Tang, Q. | PDF | N/A | Auto-methylation of the histone methyltransferase SetDB1 at its histone-mimic motifs ensures the spreading and maintenance of heterochromatin | | 以下是这段文字的中文翻译:
秀丽隐杆线虫病原体回避跨代表观遗传的分子需求
翻译说明: - "Molecular Requirements" 翻译为“分子需求” - "C. elegans" 是模式生物“秀丽隐杆线虫”的拉丁学名 - "Transgenerational Epigenetic Inheritance" 翻译为“跨代表观遗传” - "Pathogen Avoidance" 翻译为“病原体回避”
希望这对你有帮助!如果需要进一步解释或调整,请告诉我。 | Kaletsky, R. | PDF | N/A | Molecular Requirements for C. elegans Transgenerational Epigenetic Inheritance of Pathogen Avoidance | | 揭示火星2020任务组装洁净室中隐藏的微生物多样性:通过分子洞察揭示新型物种的持久性与毅力,挑战宏基因组测序的极限
这段文字描述了在火星2020任务组装洁净室中,通过分子层面的研究,揭示了隐藏的微生物多样性。这些新型物种展现了持久性和毅力,甚至挑战了现有的宏基因组测序技术。 | Muthamilselvi Sivabalan, S. K. | PDF | N/A | Unveiling Hidden Microbial Diversity in Mars2020 Mission Assembly Cleanrooms withMolecular Insights into the Persistent andPerseverance of Novel Species DefyingMetagenome Sequencing | | 开发用于濒危物种非侵入性健康监测的宏基因组学方法:揭示粪便样本中隐藏的微生物威胁 | Sapino, R. | PDF | N/A | Development of metagenomic methods for non-invasive health monitoring of endangered species: Unveiling hidden microbial threats in fecal samples | | IFNBoost: 一种用于识别诱导IFNγ肽的可解释计算模型 | Azad, I. u. h. | PDF | N/A | IFNBoost: An interpretable computational model for identifying IFNγ inducing peptides | | 从公开数据中识别免疫原性表位的领域特定语言模型方法:EpitopeMiner | Tan, W. K. | PDF | N/A | A Domain-Specific Language Model Approach for Identifying Immunogenic Epitopes from Publicly Available Data: EpitopeMiner | | 乳腺癌亚型的蛋白质组学分析揭示了决定恶性行为侵袭性的基质贡献 | Burton, J. B. | PDF | N/A | Proteomic Analysis of Breast Cancer Subtypes Identifies Stromal Contributions that Dictate Aggressive Malignant Behavior | | 以下是这段文字的中文翻译:
药物诱导的癌症持续性的数学表征
这个标题描述了一个研究领域,旨在通过数学方法分析和描述药物如何导致癌症细胞进入持续性状态(即暂时停止增殖但仍存活的细胞状态)。这种研究通常涉及数学模型、统计分析或计算模拟,以揭示药物作用机制和癌症细胞行为的动态变化。 | Park, J. T. | PDF | N/A | Mathematical Characterization of Drug-Induced Persistence in Cancer | | B7-H3作为一种双重临床相关检查点和抗体药物偶联物靶点,在腺癌和神经内分泌前列腺癌中均有表达 | Sharma, S. | PDF | N/A | B7-H3 as a Dual Clinically Relevant Checkpoint and Antibody Drug Conjugate Target Expressed Across Adenocarcinoma and Neuroendocrine Prostate Cancers | | 利用slac1-2玉米突变体研究气孔动态对农艺性状的作用 | Twohey, R. J. | PDF | N/A | Investigating the role of stomatal dynamics on agronomic traits using a slac1-2 Zea mays mutant | | 高频Wus2集成转化工具包提高了Cas9编辑效率,并在高粱中扩展了SpRY的应用能力。 | Shen, J. | PDF | N/A | High-frequency Wus2-integrated transformation toolkit enhances Cas9 editing efficiency and expands capability with SpRY in sorghum | | 顺式调控突变驱动组织特异性亚功能化,调节驯化过程中大豆种子颜色的sRNA位点 | Vodkin, L. | PDF | N/A | Cis-regulatory Mutations Drive Tissue-specific Subfunctionalization of sRNA loci Regulating Soybean Seed Color During Domestication | | 紫花苜蓿对田间病原生物组的转录组响应 | Nemchinov, L. G. | PDF | N/A | Alfalfa transcriptomic responses to the field pathobiome | | 来自原始和受影响的栖息地的两种Halophila stipulacea海草种群,对单一和组合的热和过量营养胁迫的转录组反应,揭示了局部适应性特征和核心胁迫响应基因 | Nguyen, H. M. | PDF | N/A | Transcriptome responses of two Halophila stipulacea seagrass populations from pristine and impacted habitats, to single and combined thermal and excess nutrient stressors, reveal local adaptive features and core stress-response genes | | 双稳态生物分子正反馈电路对全局参数扰动的鲁棒性 | Chorasiya, G. | PDF | N/A | Robustness of a Bistable Biomolecular PositiveFeedback Circuit to Global Parametric Perturbations | | 巨噬细胞耗竭恢复背根神经节微环境并预防硼替佐米诱导的神经病变中的轴突变性 | Thomsen, M. B. | PDF | N/A | Macrophage depletion restores the DRG microenvironment and prevents axon degeneration in bortezomib-induced neuropathy | | AAV递送的抗PC-OxPL抗体片段:一种靶向ALS的新型治疗方法 | Gomes-Duarte, A. | PDF | N/A | AAV-Delivered Anti-PC-OxPL Antibody Fragments: A NovelTherapeutic Approach to Target ALS | | 高速绘制全鼠外周神经的亚细胞分辨率图谱 | Shi, M.-Y. | PDF | N/A | High-speed mapping of whole-mouse peripheral nerves at subcellular resolution | | 独特的结肠炎相关巨噬细胞驱动NOD2依赖的细菌感知与肠道稳态 | Katkar, G. | PDF | N/A | Distinct Colitis-Associated Macrophages Drive NOD2-DependentBacterial Sensing and Gut Homeostasis | | 干旱对西尼罗河病毒风险的矛盾影响:来自长期生态数据的洞见 | Sambado, S. | PDF | N/A | The paradoxical impact of drought on West Nile virus risk: insights from long-term ecological data | | 探索物种丰富的蜥蜴属(Liolaemus)中的遗传多样性:距离隔离、体型和环境变异之间的相互作用 | Ruiz Monachesi, M. R. | PDF | N/A | Exploring genetic diversity in the species-rich genus Liolaemus: The interplay among isolation by distance, body size, and environmental variability | | 从头自生工程活功能材料 | Hammad, H. M. | PDF | N/A | De novo Autogenic Engineered Living Functional Materials | | AlphaCross-XL:一个无缝工具,用于自动化且蛋白质组规模的交联肽段映射到三维蛋白质结构上 | Shenoy, S. V. | PDF | N/A | AlphaCross-XL: a seamless tool for automated and proteome-scale map-ping of crosslinked peptides onto three-dimensional protein structures | | 原位核磁共振(NMR)揭示了一种位于外膜蛋白中的pH传感器基序,该基序驱动细菌囊泡的产生。 | Wood, N. A. | PDF | N/A | In situ NMR reveals a pH sensor motif in an outer membrane protein that drives bacterial vesicle production | | 大分子二氨基苯并咪唑共轭物激活STING | Arora, K. | PDF | N/A | Macromolecular Diamidobenzimidazole Conjugates Activate STING | | 卷曲螺旋结构域中的疏水核心对于NRC抗病小体的功能至关重要。 | Wang, H.-Y. | PDF | N/A | A hydrophobic core in the coiled-coil domain essential for NRC resistosome function | | 多病灶诱导加剧了子宫内膜异位症小鼠模型中由神经炎症驱动的中枢敏化。 | Harvey, M. E. | PDF | N/A | Multiple lesion inductions intensify central sensitization driven by neuroinflammation in a mouse model of endometriosis. | | 双探针连接原位杂交结合滚环扩增技术用于高多重空间转录组学 | Maguire, S. | PDF | N/A | Dual Probe Ligation In Situ Hybridization with Rolling-Circle Amplification for High-Plex Spatial Transcriptomics | | 宿主微RNA-31-5p通过限制RNA结合蛋白KHDRBS3介导的病毒基因表达,抑制致癌疱疹病毒的裂解再激活。 | Lee, S. M. | PDF | N/A | Host microRNA-31-5p represses oncogenic herpesvirus lytic reactivation by restricting the RNA-binding protein KHDRBS3-mediated viral gene expression | | 以下是您提供的英文内容的中文翻译:
猪循环死亡后捐献(DCD)心脏在长时间离体工作模式灌注下的左心室转录组和细胞外囊泡来源的miRNA研究
翻译说明: 1. Left ventricular transcriptome:左心室转录组,指左心室组织中基因表达的整体情况。 2. extracellular vesicle-derived miRNAs:细胞外囊泡来源的miRNA,指从细胞外囊泡中提取的微小RNA分子。 3. porcine donation after circulatory death (DCD) hearts:猪循环死亡后捐献(DCD)心脏,指在循环停止后捐献的猪心脏。 4. prolonged working mode ex situ perfusion:长时间离体工作模式灌注,指在体外环境下对心脏进行长时间的功能性灌注。
希望这个翻译对您有帮助!如果需要进一步调整或补充,请随时告诉我。 | Wang, F. | PDF | N/A | Left ventricular transcriptome and extracellular vesicle-derived miRNAs in porcine donation after circulatory death (DCD) hearts undergoing prolonged working mode ex situ perfusion | | 外源性淀粉样蛋白序列:它们在淀粉样蛋白-β异型聚集中的作用 | Seira Curto, J. | PDF | N/A | Exogenous Amyloid Sequences: Their Role in Amyloid-Beta Heterotypic Aggregation | | 识别RapidFire质谱中的新型假阳性机制及其在药物发现中的应用 | Pearson, L.-A. | PDF | N/A | Identification of a novel false-positive mechanism in RapidFire mass spectrometry and application in drug discovery | | 脂质纳米颗粒用于递送CRISPR/Cas9机制,以实现CFTR的位点特异性整合和突变无关的疾病拯救 | Foley, R. A. | PDF | N/A | Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site-Specific Integration of CFTR and Mutation-Agnostic Disease Rescue | | 通过广泛突变扫描探索二氢叶酸还原酶蛋白家族不同同源物中的抗生素耐药性 | Romanowicz, K. | PDF | N/A | Exploring Antibiotic Resistance in Diverse Homologs of the Dihydrofolate Reductase Protein Family through Broad Mutational Scanning | | 质体醌氧化还原状态通过RpaA和ROS依赖的调控网络影响羧酶体的完整性。 | Santos-Merino, M. | PDF | N/A | Plastoquinone redox status influences carboxysome integrity via a RpaA- and ROS-dependent regulatory network | | CD8+ T细胞在免疫抑制后介导了疫苗接种诱导的潜伏性结核分枝杆菌感染的淋巴系统控制,而B细胞则并非必需。 | Miranda-Hernandez, S. | PDF | N/A | CD8+ T cells mediate vaccination-induced lymphatic containment of latent Mycobacterium tuberculosis infection following immunosuppression, while B cells are dispensable | | 无菌或病原体诱导的内溶酶体损伤会激活人肠道上皮细胞中的NLRP6炎症小体。 | Boegli, A. | PDF | N/A | Sterile- or pathogen-induced endolysosomal damage activate the NLRP6 inflammasome in human intestinal epithelial cells | | 一种泛素样蛋白控制着细菌VIIb型分泌系统的组装。 | Oka, G. U. | PDF | N/A | A ubiquitin-like protein controls assembly of a bacterial Type VIIb secretion system | | 动静脉瘘建立后人类静脉的单细胞景观及其对成熟失败的影响 | Martinez, L. | PDF | N/A | The Single Cell Landscape of the Human Vein After Arteriovenous Fistula Creation and Implications for Maturation Failure | | BAHCC1通过拮抗SIN3A-HDAC1促进神经元细胞中的基因表达。 | Monziani, A. | PDF | N/A | BAHCC1 promotes gene expression in neuronal cells by antagonizing SIN3A-HDAC1 | | 分化路径决定了人类巨噬细胞的身份 | Frenis, K. | PDF | N/A | Path of differentiation defines human macrophage identity | | 26S蛋白酶体与Hsp70共伴侣Bag1复合物的结构揭示了泛素非依赖性蛋白酶体降解的新机制 | Maestro-Lopez, M. | PDF | N/A | Structures of the 26S proteasome in complex with the Hsp70 cochaperone Bag1 reveal a novel mechanism of ubiquitin-independent proteasomal degradation | | 在乳腺癌中,转移性细胞的可塑性通过SOX9在有丝分裂期间的功能得以维持。 | Zippo, A. | PDF | N/A | Metastatic cell plasticity is maintained by SOX9 function during mitosis in breast cancer | | 以下是将这段英文翻译成中文的结果:
一种用于从条件培养基中分离的细胞外囊泡进行高通量蛋白质组分析的96孔超滤方法
翻译说明: 1. "96-well" 翻译为 "96孔",指实验中使用96孔板。 2. "ultrafiltration approach" 翻译为 "超滤方法",指实验采用超滤技术。 3. "high-throughput proteome analysis" 翻译为 "高通量蛋白质组分析",指对蛋白质组进行大规模、快速的分析。 4. "extracellular vesicles" 翻译为 "细胞外囊泡",是细胞分泌的一种微小膜结构。 5. "isolated from conditioned medium" 翻译为 "从条件培养基中分离的",指实验材料是从条件培养基中提取的。
这种翻译保留了原文的专业性和准确性,同时使中文表达清晰易懂。 | Pauwels, J. | PDF | N/A | A 96well ultrafiltration approach for the high-throughput proteome analysis of extracellular vesicles isolated from conditioned medium | | 大海捞针:一种用于检测感染自然宿主种群的罕见蠕虫寄生虫的微滴数字聚合酶链反应检测方法 | Fouilloux, C. A. | PDF | N/A | Needle in a haystack: A droplet digital polymerase chain reaction assay to detect rare helminth parasites infecting natural host populations | | 岛屿法则实例的表型与发育解析 | Nolte, M. J. | PDF | N/A | Phenotypic and Developmental Dissection of an Instance of the Island Rule | | 《南美洲南部和南极洲海洋Verrucariaceae专著的初步研究:综合分类学揭示先前未知的多样性》
在这项研究中,我们致力于对南美洲南部和南极洲海域的Verrucariaceae科(一种海洋真菌)进行专著式的系统研究。通过整合多种分类学方法,我们揭示了该地区Verrucariaceae科中先前未被认识的多样性。这一发现不仅丰富了我们对海洋真菌多样性的理解,也为未来相关研究提供了新的视角和基础。 | Fernandez-Costas, D. | PDF | N/A | Towards a monograph of marine Verrucariaceae in Southern South America and maritime Antarctica: Integrative taxonomy reveals a previously unknown diversity | | 菌株背景与7号染色体非整倍性相互作用,决定白色念珠菌的共生和毒力表型。 | Mishra, A. | PDF | N/A | Strain background interacts with chromosome 7 aneuploidy to determine commensal and virulence phenotypes in Candida albicans | | 全基因组范围内鉴定参与甲虫臭腺防御功能的基因,发现Laccase2是负责合成有毒对苯醌的酚氧化酶。 | Atika, B. | PDF | N/A | Genome-wide identification of genes involved in beetle odoriferous defensive stink gland function recognizes Laccase2 as the phenoloxidase responsible for toxic para-benzoquinone synthesis | | 探索转座因子在果蝇物种寿命性别差异中的作用 | Merenciano, M. | PDF | N/A | Exploring the role of transposable elements to sex gap in longevity in Drosophila species | | 帕特西细菌(Patescibacteria)的IV型分泌系统与细菌单层膜接合机制同源。 | Quinonero-Coronel, M. d. M. | PDF | N/A | The Type IV Secretion System of Patescibacteria is homologous to the bacterial monoderm conjugation machinery | | 为乌林鸮(Strix uralensis)提供的高质量参考基因组,使得研究细胞培养成为可能,这为濒危物种的基因组资源研究开辟了新途径。 | Chrysostomakis, I. | PDF | N/A | A high-quality reference genome for the Ural Owl (Strix uralensis) enables investigations of cell cultures as a genomic resource for endangered species | | 混合测序揭示了小金黄藻病毒(Chrysochromulina parva virus)的基因组,并突显了其独特的复制策略。 | Nash, D. | PDF | N/A | Hybrid sequencing reveals the genome of a Chrysochromulina parva virus and highlight its distinct replication strategy | | 数字重编程解码细胞命运变化的表观遗传障碍 | Janeva, A. | PDF | N/A | Digital Reprogramming Decodes Epigenetic Barriers of Cell Fate Changes | | 解析利血平的生物合成途径 | Jiang, Y. | PDF | N/A | Elucidation of the biosynthetic pathway of reserpine | | 解析利血平的生物合成途径 | Cao, J. | PDF | N/A | Elucidation of the biosynthetic pathway of reserpine | | 区域特异性平均场模型增强了局部和全局脑动态的模拟 | Lorenzi, R. M. | PDF | N/A | Region-specific mean field models enhance simulations of local and global brain dynamics | | mzQuality:一个用于目标质谱测量质量监控和报告的工具 | van der Peet, M. | PDF | N/A | mzQuality: A tool for quality monitoring and reporting of targeted mass spectrometry measurements | | 基于化学的向量从非靶向质谱数据中绘制自然生物群系的化学空间。 | Peets, P. | PDF | N/A | Chemistry-based vectors map the chemical space of natural biomes from untargeted mass spectrometry data | | 构建昆虫转向电路的框架 | Mitchell, R. | PDF | N/A | A framework for constructing insect steering circuits | | 病理性Ataxin-3聚集的变构调节:迈向脊髓小脑共济失调3型治疗的途径 | Silva, A. | PDF | N/A | Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies | | 物理限制调节线虫运动能力的转变 | Dey, S. | PDF | N/A | Physical confinement regulates transition in nematode motility | | 适应性可塑性肿瘤细胞调节结直肠癌中MAPK靶向治疗的反应 | Villarreal, O. E. | PDF | N/A | Adaptive Plasticity Tumor Cells Modulate MAPK-Targeting Therapy Response in Colorectal Cancer | | T细胞靶点的泛癌图谱 | Li, G. | PDF | N/A | A pan-cancer atlas of T cell targets | | 慢性淋巴细胞白血病在异基因干细胞移植后的演变 | Garber, H. R. | PDF | N/A | Evolution of chronic lymphocytic leukemia after allogeneic stem cell transplant | | 空间分析揭示了儿童骨肉瘤肺转移中区域独特的微环境及可靶向的免疫抑制机制。 | Eigenbrood, J. | PDF | N/A | Spatial profiling identifies regionally distinct microenvironments and targetable immunosuppressive mechanisms in pediatric osteosarcoma pulmonary metastases. | | 染色体外环状DNA促进炎症和肝细胞癌的发展 | Chan, L. K. | PDF | N/A | Extrachromosomal circular DNA promotes inflammation and hepatocellular carcinoma development | | 多种微管去稳定药物在内皮细胞中诱导等效的分子通路反应 | Horin, L. J. | PDF | N/A | Diverse microtubule-destabilizing drugs induce equivalent molecular pathway responses in endothelial cells | | 17β-雌二醇通过对抗病理性微管重塑以增强心脏功能 | Moon, R. | PDF | N/A | 17β-Estradiol Counteracts Pathological Microtubule Remodeling To Enhance Cardiac Function | | 冬季黑麦根系生长及其对田间条件下氮磷缺失的响应与可塑性研究。 | Nyameasem, J. K. | PDF | N/A | Winter rye root growth and plasticity in response to nitrogen and phosphorus omission under field conditions. | | 整合空间转录组分析揭示了TaMCO3编码的铁氧化酶在小麦根尖铁动员中的作用 | Joon, R. | PDF | N/A | Integrative spatial transcriptomic analysis pinpoints the role of TaMCO3 encoding ferroxidase in wheat root tip iron mobilization | | 根冠特异性转录组学鉴定出NAC转录因子SOMBRERO作为生长素梯度的多功能调节因子 | Wang, P. | PDF | N/A | Root Cap-Specific Transcriptomics Identify the NAC Transcription Factor SOMBRERO as a Versatile Regulator of Auxin Gradients | | 对由玉米转座子诱导的体细胞突变进行超深度测序 | Scherer, J. | PDF | N/A | Ultra-deep sequencing of somatic mutations induced by a maize transposon | | 进化上保守的机制用于在早期嗅觉回路中重新格式化气味浓度 | Shen, Y. | PDF | N/A | An evolutionarily conserved mechanism for reformatting odor concentration in early olfactory circuits | | 通过miR-130b调节B细胞耐受性和自身免疫 | Herrero-Fernandez, B. | PDF | N/A | Regulation of B cell tolerance and autoimmunity by miR-130b | | 在饥饿状态下,肥胖小鼠骨骼肌和肝脏中关键调节代谢物的全局反应性丧失以及酶蛋白水平的升高,表现为代谢失调。 | Li, D. | PDF | N/A | Global loss of responsiveness in key regulator metabolites and elevated enzyme proteins as metabolic dysregulation in skeletal muscle and liver of obese mice during starvation | | 广泛的基因组进化使玉米在稳定的禾本科植物部落中独树一帜。 | Stitzer, M. C. | PDF | N/A | Extensive genome evolution distinguishes maize within a stable tribe of grasses | | 转录组挖掘揭示了鳞翅目昆虫中iflaviruses的多样性和进化 | van Valkengoed, D. | PDF | N/A | Transcriptome mining reveals diversity and evolution of iflaviruses in Lepidoptera | | 一种基于蛋白质组学的稳健方法,用于识别合成糖胺聚糖模拟物的优选蛋白质靶标 | Afosah, D. K. | PDF | N/A | A Robust Proteomics-Based Method for Identifying Preferred Protein Targets of Synthetic Glycosaminoglycan Mimetics | | 一个用于Rubisco突变体变体的蓝藻筛选平台 | Hoffmann, U. A. | PDF | N/A | A cyanobacterial screening platform for Rubisco mutant variants | | 人类基因表达中非编码RNA调控的计算机模拟分析:一种系统性的计算方法以理解调控网络 | Akbar, A. | PDF | N/A | In Silico Analysis of Non-Coding RNA Regulation in Human Gene Expression: A Systematic Computational Approach to Understanding Regulatory Networks | | 数据融合用于基于深度学习的综合物种识别 | Koesters, L. M. | PDF | N/A | Data Fusion for Integrative Species Identification Using Deep Learning | | 细菌生物膜中的交流电渗:电生理学实验的警示故事 | Carneiro da Cunha Martorelli, V. | PDF | N/A | AC electro-osmosis in bacterial biofilms: a cautionary tale for electrophysiology experiments | | 单分子镊子解码脂质双层中膜蛋白的隐藏二聚化模式 | Sadongo, V. W. | PDF | N/A | Single-molecule tweezers decoding hidden dimerization patterns of membrane proteins within lipid bilayers | | 腔内压力触发内皮屏障的快速且持久的强化。 | Bancaud, A. | PDF | N/A | Intraluminal pressure triggers a rapid and persistent reinforcement of endothelial barriers | | 对体内弹性应力传感器进行3D动态多尺度力与形状分析 | Jurado Jimenez, A. | PDF | N/A | 3D dynamic multiscale force and shape analysis of in-vivo elastic stress sensors | | 针对高风险KMT2A重排白血病的双特异性CAR-iNKT细胞免疫疗法以NKG2D依赖方式优于CAR-T,并能够根除软脑膜疾病。 | Ren, H. | PDF | N/A | Bi-specific CAR-iNKT cell immunotherapy for high-risk KMT2A-rearranged leukemia outperforms CAR-T in an NKG2D-dependent manner and eradicates leptomeningeal disease | | 在血管紧张素II驱动的转录变化中,近端胸主动脉中的平滑肌细胞和成纤维细胞在胚胎起源方面表现出微小差异。 | Ito, S. | PDF | N/A | Smooth Muscle Cells and Fibroblasts in the Proximal Thoracic Aorta Exhibit Minor Differences Between Embryonic Origins in Angiotensin II-driven Transcriptional Alterations | | 迷幻药物介导的大鼠全身麻醉逆转及脑动力学恢复 | Huels, E. R. | PDF | N/A | Psychedelic-mediated Reversal of General Anesthesia and Restoration of Brain Dynamics in Rat | | 肠道病毒D68的2A蛋白酶导致核孔复合体功能障碍和运动神经元毒性 | Zinn, K. M. | PDF | N/A | Enterovirus D68 2A protease causes nuclear pore complex dysfunction and motor neuron toxicity | | 纹状体价值衰减梯度解释了多巴胺模式和强化学习计算的区域差异 | Kato, A. | PDF | N/A | Striatal Gradient in Value-Decay Explains Regional Differences in Dopamine Patterns and Reinforcement Learning Computations | | 生物合成可塑性使CD8+ T细胞在营养压力下保持功能韧性 | Scaglione, M. | PDF | N/A | Biosynthetic plasticity enables CD8+ T cell functional resilience under nutrient stress | | 内源性逆转录病毒驱动的Pcgf5在合子基因组激活和非经典印记中起关键作用 | Mashiko, S. | PDF | N/A | Endogenous retrovirus-driven Pcgf5 plays critical roles in zygotic genome activation and noncanonical imprinting | | 西澳大利亚面临的热干旱新威胁 | Mastrantonis, S. | PDF | N/A | The emerging threat of hot drought in Western Australia | | 斯蒂芬按蚊幼虫栖息地的超生产力及其在非洲幼虫源管理中的相关性 | Yared, S. | PDF | N/A | Anopheles stephensi larval habitat superproductivity and its relevance for larval source management in Africa | | 实验性添加野花增加了城市农业生态系统中的授粉。 | Ellis, E. E. | PDF | N/A | Experimental wildflower additions increase pollination in urban agroecosystems | | 有害突变与在空间结构二倍体群体中对性的选择 | Fouqueau, L. | PDF | N/A | Deleterious mutations and selection for sex in spatially structured, diploid populations | | 隐秘多样性对鳄目(Crocodylia)多样化动态分析的影响 | Darlim, G. | PDF | N/A | The effects of cryptic diversity on diversification dynamics analyses in Crocodylia | | 检测和避免基因组训练序列模型中的基于同源性的数据泄露 | Rafi, A. M. | PDF | N/A | Detecting and avoiding homology-based data leakage in genome-trained sequence models | | 在神经退行性疾病分类任务中,缺失数据与待预测标签相关的影响 | Prakash, M. | PDF | N/A | Impact of missing data correlated with labels to be predicted in neurodegeneration classification tasks | | 早期非小细胞肺癌质子治疗中肿瘤控制的剂量分割依赖性 | Jeong, J. | PDF | N/A | The fractionation dependence of tumor control in proton therapy for early-stage non-small cell lung cancer | | 多尺度模拟CD47-SIRPα复合物介导的膜粘附 | Hou, R. | PDF | N/A | Multi-scale simulations of membrane adhesion mediated by CD47-SIRPα complexes | | 莱茵衣藻中高能淬灭与状态转换之间的相互作用:单细胞方法 | Lahlou, A. | PDF | N/A | Interplay between high-energy quenching and state transitions in Chlamydomonas reinhardtii: a single-cell approach | | 氧化磷酸化(OXPHOS)促进黑色素瘤肺和脑转移的形成与生长 | Guerrieri, R. A. | PDF | N/A | Oxidative Phosphorylation (OXPHOS) Promotes the Formation and Growth of Melanoma Lung and Brain Metastases | | E2F4转录抑制因子是结肠癌对伊立替康(CPT-11)耐药的关键机制调节因子。 | Matsubara, J. | PDF | N/A | The E2F4 transcriptional repressor is a key mechanistic regulator of colon cancer resistance to irinotecan (CPT-11). | | 将siRNA通过脂质纳米颗粒递送至背根神经节神经元以治疗疼痛 | Han, X. | PDF | N/A | Lipid nanoparticle delivery of siRNA to dorsal root ganglion neurons to treat pain | | 无监督学习揭示了蜘蛛在腿部丧失和再生后步态的快速适应能力。 | Kane, S. A. | PDF | N/A | Unsupervised learning reveals rapid gait adaption after leg loss and regrowth in spiders | | 检测未暴露个体中对H5N1 2.3.4.4b分支流感病毒的低水平预先存在的体液免疫 | Daniel, K. | PDF | N/A | Detection of low pre-existing humoral immunity against influenza virus H5N1 clade 2.3.4.4b in unexposed individuals | | 利用粗糙脉孢菌与丁香假单胞菌模型探究真菌先天免疫的分子机制 | Stark, F. G. | PDF | N/A | Molecular Insights into Fungal Innate Immunity Using the Neurospora crassa - Pseudomonas syringae Model | | CD226在结核病期间识别效应CD8+ T细胞,并协同刺激对结核分枝杆菌感染的巨噬细胞的识别。 | Shinkawa, T. | PDF | N/A | CD226 identifies effector CD8+ T cells during tuberculosis and costimulates recognition of Mycobacterium tuberculosis-infected macrophages | | CD4 T细胞功能障碍与慢性结核病期间细菌复发有关。 | Chang, E. | PDF | N/A | CD4 T cell dysfunction is associated with bacterial recrudescence during chronic tuberculosis. | | 环境DNA元条形码技术与鱼类基于等级的丰度之间存在强相关性。 | Littlefair, J. E. | PDF | N/A | A strong relationship between environmental DNA metabarcoding and rank-based abundance of fish | | 季节性病毒分流增强催化了马尾藻海次表层氧最大值 | Gilbert, N. E. | PDF | N/A | Seasonal Enhancement of the Viral Shunt Catalyzes a Subsurface Oxygen Maximum in the Sargasso Sea | | 改进后的灰鲸基因组组装凸显了异种参考基因组选择如何影响基因组多样性估计 | Bruniche-Olsen, A. | PDF | N/A | An improved gray whale assembly highlights how allospecific reference-genome choice can affect genomic diversity estimates | | 空间着丝粒分布模式的模拟与定量分析 | Keikhosravi, A. | PDF | N/A | Simulation and quantitative analysis of spatial centromere distributionpatterns | | 探索不同气候带几内亚鸟与鸡种群的选择基因组特征:非洲、亚洲和欧洲的比较分析 研究论文 | Kennedy, G. M. | PDF | N/A | Exploring Genomic Signatures of Selection in Guineafowl and Chicken Populations Across Diverse Climatic Zones: A Comparative Analysis of Africa, Asia, and Europe Research Article | | 细胞绘画技术用于原代人肝细胞的细胞毒性和作用机制分析 | Ewald, J. D. | PDF | N/A | Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes | | 共享和独特的音素和韵律在腹侧和背侧语音流中的表征动态 | Baek, S.-C. | PDF | N/A | Shared and distinct representational dynamics of phonemes and prosody in ventral and dorsal speech streams |