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网格细胞放电的空间周期性由二维轨迹的神经序列编码解释 R.G., R. PDF N/A Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories
利用HaloTag技术可视化hiPSC衍生的单细胞和类器官中PIEZO1的定位与活性 Bertaccini, G. A. PDF N/A Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology
斑马鱼活体成像显示,在早期发育过程中,只有极少比例的脊髓运动神经元会死亡。 Jia, H. PDF N/A Zebrafish live imaging reveals a surprisingly small percentage of spinal cord motor neurons die during early development
将结构假设融入单细胞RNA测序数据的降维过程中,以识别小型基因集 Hackenberg, M. PDF N/A Infusing structural assumptions into dimensionality reduction for single-cell RNA sequencing data to identify small gene sets
通过对逐步对接的寡聚底物进行分子动力学模拟,实现高效聚酰胺酶的KnowVolution进化 Puetz, H. PDF N/A KnowVolution of an efficient polyamidase through molecular dynamics simulations of incrementally docked oligomeric substrates
时光飞逝:果蝇头部单核RNA测序衰老时钟揭示了性别偏向的衰老过程 Tennant, N. PDF N/A TimeFlies: an snRNA-seq aging clock for the fruit fly head sheds light on sex-biased aging
假定的肺炎克雷伯菌生态梯度 Liu, S. PDF N/A A putative ecocline in Klebsiella pneumoniae
BAHCC1通过拮抗SIN3A-HDAC1促进神经元细胞中的基因表达。 Monziani, A. PDF N/A BAHCC1 promotes gene expression in neuronal cells by antagonizing SIN3A-HDAC1
可转座元件在重度抑郁症患者的大脑中失调 Truby, N. L. PDF N/A Transposable Elements are Dysregulated in Brains of Individuals with Major Depressive Disorder
JNK通过受体聚集蛋白GIT1(ArfGAP1)调节GABAAR在细胞表面的表达。 Varidaki, A. PDF N/A JNK regulates GABAAR expression at the cell surface via the receptor clustering protein GIT1 (ArfGAP1)
全球各地的神话模式反映了人类从非洲向外扩张的历史。 Delbrassine, H. PDF N/A Worldwide patterns in mythology echo the human expansion out of Africa
拟南芥遮荫响应基因调控中的转录动态与染色质可及性研究 Paulisic, S. PDF N/A Transcriptional Dynamics and Chromatin Accessibility in the Regulation of Shade-Responsive Genes in Arabidopsis
通过泛基因组分析揭示了代谢反应的多样化遗传基础 Ardalani, O. PDF N/A A Diverse Genetic Basis for Metabolic Reactions is Revealed Through Pangenome analysis
空间异质性与青少年功能连接发展的亚型 Li, H. PDF N/A Spatial Heterogeneity and Subtypes of Functional Connectivity Development in Youth
将自我中心地图和异我中心地图结合以实现灵活导航 Shani, D. PDF N/A Composing egocentric and allocentric maps for flexible navigation
尖峰LIF模型揭示了生长抑素和钙结合蛋白神经元在V1区产生振荡中的作用。 Milea, D. PDF N/A A spiking LIF model captures the role of Somatostatin and Parvalbumin neurons in generating oscillations in V1
突触组结构塑造小鼠大脑的区域动态 Hansen, J. Y. PDF N/A Synaptome architecture shapes regional dynamics in the mouse brain
前馈和反馈抑制在调节θ-γ跨频相互作用中的作用 Chalkiadakis, D. PDF N/A The Role of Feedforward and Feedback Inhibition in Modulating Theta-Gamma Cross-Frequency Interactions
毛细胞钙离子通道的门控调节耳蜗神经元的活动。 Karagulyan, N. PDF N/A Gating of hair cell Ca2+ channels governs the activity of cochlear neurons
SOX9在血吸虫病引起的肝损伤中,对由肌成纤维细胞驱动的肝肉芽肿完整性及实质修复起着至关重要的作用。 Su, K. PDF N/A SOX9 plays an essential role in myofibroblast driven hepatic granuloma integrity and parenchymal repair during schistosomiasis-induced liver damage
雄激素在流感病毒感染期间保护ILC2s免受功能抑制 Kadel, S. PDF N/A ANDROGENS PROTECT ILC2S FROM FUNCTIONAL SUPPRESSION DURING INFLUENZA VIRUS INFECTION
CAR T细胞和溶瘤病毒动力学及其在胶质母细胞瘤联合治疗中的成功决定因素 Conte, M. PDF N/A CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma
使用编码膜结合HIV包膜三聚体的mRNA疫苗在动物模型中诱导产生了中和抗体。 Ramezani-Rad, P. PDF N/A Vaccination with mRNA-encoded membrane-bound HIV Envelope trimer induces neutralizing antibodies in animal models
已批准的口服核苷类似物组合在体外和体内对甲病毒具有强效抑制作用。 Verwimp, S. PDF N/A Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo
在Hedgehog信号转导过程中,通过多个Fused磷酸化位点激活Ci转录因子的机制的生理学分析 Kim, H. PDF N/A Physiological analysis of the mechanism of Ci transcription factor activation through multiple Fused phosphorylation sites in Hedgehog signal transduction
温度和降水通过调节生长季节的开始,共同影响植物微生物群落的形成。 in 't Zandt, D. PDF N/A Temperature and precipitation interactively shape the plant microbiome by regulating the start of the growing season
物种分布建模在保护科学中的应用:新的预测因子层、可复现的代码以及对加利福尼亚保护区的评估 MacDonald, Z. G. PDF N/A Species distribution modeling for conservation science: new predictor layers, reproducible code, and an evaluation of California protected areas
全球变暖下珊瑚存续的窗口期正在迅速关闭 Bozec, Y.-M. PDF N/A A rapidly closing window for coral persistence under global warming
评估动态系统中物种丰度模型的预测准确性 Brown, C. J. PDF N/A Assessing predictive accuracy of species abundance models in dynamic systems
评估猪流行性腹泻病毒RNA在养猪业运输车辆上的污染情况 Parker, T. B. PDF N/A Evaluation of porcine epidemic diarrhea virus RNA contamination on swine industry transportation vehicles
无监督多动物追踪用于定量行为学 Li, Y. PDF N/A Unsupervised multi-animal tracking for quantitative ethology
MutBERT:概率基因组表示提升基因组学基础模型

在这段话中,"MutBERT" 是一个模型或技术的名称,可能是指一种基于BERT(Bidirectional Encoder Representations from Transformers)架构的变体,专门用于基因组学领域。"Probabilistic Genome Representation" 指的是使用概率方法来表示基因组数据,这种方法可能能够更好地捕捉基因组中的不确定性和复杂性。"Improves Genomics Foundation Models" 意味着这种表示方法能够提升基因组学基础模型的性能或效果。整体而言,这段话描述了一种新的技术或方法,旨在通过改进基因组数据的表示方式来增强基因组学领域的基础模型。 | Long, W. | PDF | N/A | MutBERT: Probabilistic Genome Representation Improves Genomics Foundation Models | | 用于无偏序列蛋白质相互作用预测的深度学习模型的准确率达到了0.65的稳定水平。 | Reim, T. | PDF | N/A | Deep learning models for unbiased sequence-based PPI prediction plateau at an accuracy of 0.65 | | 霍奇金淋巴瘤微环境的基因组尺度空间定位揭示了肿瘤细胞存活的关键因素 | Shanmugam, V. | PDF | N/A | Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors | | RSV NS1与MED25 ACID结构域之间的双重相互作用重塑了抗病毒反应 | Ait-Mouhoub, C. | PDF | N/A | A dual interaction between RSV NS1 and MED25 ACID domain reshapes antiviral responses | | TRPV1功能调控中的一项进化新特性:对仅限于狭鼻猴类灵长类动物的显性负性异构体的特征描述 | Cancino, S. | PDF | N/A | An Evolutionary Novelty in TRPV1 Functional Regulation: Characterization of a Dominant-Negative Isoform Exclusive to Catarrhine Primates | | 城市群岛中跨时间尺度的人口历史 | Howell, E. K. | PDF | N/A | Population history across timescales in an urban archipelago | | 评估海草及其水生近亲中丛枝菌根保守基因的进化轨迹 | Ettinger, C. L. | PDF | N/A | Assessing the Evolutionary Trajectory of Arbuscular Mycorrhizal Conserved Genes in Seagrasses and Aquatic Close Relatives | | 通过基于纳米孔技术的非整倍体和基因拷贝数变异检测与LeishGenApp应用,发现婴儿利什曼原虫中的耐药性生物标志物 | Carrasco Martin, M. | PDF | N/A | Drug-Resistance Biomarkers in Leishmania infantum through Nanopore-Based Detection of Aneuploidy and Gene Copy Number Variations with LeishGenApp | | 跨细胞类型的系统遗传学揭示了eQTL在小鼠神经祖细胞发育轨迹中多个点的影响 | Aydin, S. | PDF | N/A | Cross cell-type systems genetics reveals the influence of eQTL at multiple points in the developmental trajectory of mouse neural progenitor cells | | 统一元回归模型用于罕见变异关联研究 | Lauer, L. | PDF | N/A | Unified meta regression models for rare variant association studies | | 通过模拟评估小型管理种群的基因分型策略 | Martin, A. A. A. | PDF | N/A | Evaluating genotyping strategies for a small managed population with simulation | | CANDI:基因组数据的自监督、置信感知去噪填补 | Foroozandeh Shahraki, M. | PDF | N/A | CANDI: self-supervised, confidence-aware denoising imputation of genomic data | | 以下是将这段英文翻译成中文的结果:

“对一种近期经历全基因组复制的淡水螺模型系统中核基因组大小及变异的表征”

翻译解释: - Characterization:表征,指对某一特性或现象进行详细描述和分析。 - nuclear genome size:核基因组大小,指细胞核内基因组的总大小。 - variation:变异,指基因组中存在的差异或变化。 - freshwater snail:淡水螺,一种生活在淡水环境中的软体动物。 - model system:模型系统,指用于科学研究的代表性生物系统。 - featuring:以……为特征,这里指该模型系统的特点。 - recent whole-genome duplication:近期全基因组复制,指基因组在进化过程中发生的整体复制事件。

整段翻译表达了对一种淡水螺模型系统中核基因组大小及其变异的研究,重点在于该物种近期经历了全基因组复制事件。 | Neiman, M. | PDF | N/A | Characterization of nuclear genome size and variation in a freshwater snail model system featuring a recent whole-genome duplication | | 生物物理建模揭示了Spo0A的转录调控机制,Spo0A是饥饿状态下枯草芽孢杆菌的主要调控因子。 | Zhang, Y. | PDF | N/A | Biophysical modeling reveals the transcriptional regulatory mechanism of Spo0A, the master regulator in starving Bacillus subtilis | | 在暴露于应激条件下时,由γ-微管蛋白-FTO-MARK4翻译微域合成的超急性反应蛋白(HARPs)能够调节癌症中的应激反应。 | Saleme, B. | PDF | N/A | Hyperacute Response Proteins (HARPs) synthesized on γ-tubulin-FTO-MARK4 translation microdomains upon exposure to stress, regulate stressresponse in cancer. | | 表面性质对颗粒与海洋粘液过滤器相互作用的影响 | Jacobi, Y. | PDF | N/A | The effect of surface properties on the interactions of particles and marine mucous filters | | 接种微生物发酵剂的卡斯蒂洛阿拉比卡咖啡豆发酵后的宏基因组、代谢组及感官特性 | Madrid-Restrepo, M. A. | PDF | N/A | Metagenomic, metabolomic and sensorial characteristics of fermented Coffea arabica L. var. Castillo beans inoculated with microbial starter cultures | | 7β-羟基类固醇脱水酶Hsh3在Sphingobium sp.菌株Chol11以及其他鞘脂单胞菌科细菌降解胆汁盐熊去氧胆酸的过程中,负责消除其7-羟基基团。 | Richtsmeier, P. | PDF | N/A | 7β-hydroxysteroid dehydratase Hsh3 eliminates the 7-hydroxy group of the bile salt ursodeoxycholate during degradation by Sphingobium sp. strain Chol11 and other Sphingomonadaceae | | 蛋白激酶C通过促进过氧化物酶体与内质网的相互作用,正向调节过氧化物酶体的生物发生。 | Borisyuk, A. | PDF | N/A | Protein Kinase C positively regulates peroxisome biogenesis by promoting peroxisome-endoplasmic reticulum interaction | | 使用基于溯祖理论的基因渗入和迁移估计进行杂交带分析 | Leache, A. | PDF | N/A | Hybrid zone analysis using coalescent-based estimates of introgression and migration | | 核孔蛋白塑造生殖颗粒结构并平衡小RNA沉默途径 | Shi, K. | PDF | N/A | Nucleoporins shape germ granule architecture and balance small RNA silencing pathways | | 一种非侵入性的清醒小鼠功能磁共振成像方法,兼容多模态技术 | Laxer, S. | PDF | N/A | A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques | | 关于痛苦与快乐处理的双重性:为什么两个效价维度可能比一个更好 | Dulberg, Z. | PDF | N/A | On the duality of pain and pleasure processing: Why two dimensions of valence may be better than one | | 镶嵌式原肠胚模型揭示了哺乳动物原肠胚前期细胞竞争的发育阶段特异性限制 | Frenster, J. D. | PDF | N/A | A mosaic gastruloid model highlights the developmental stage-specific restriction of cell competition in mammalian pre-gastrulation | | 单分子线粒体DNA成像揭示了由发育瓶颈和体内不同器官中的选择所塑造的异质性动态。 | Chandrasegaram, R. | PDF | N/A | Single-molecule mitochondrial DNA imaging reveals heteroplasmy dynamics shaped by developmental bottlenecks and selection in different organs in vivo | | Tet3介导O-GlcNAcylation诱导的髓鞘再生 | Li, Y. | PDF | N/A | Tet3 Mediates O-GlcNAcylation-Induced Remyelination | | 变暖对植物与真菌内生菌共生关系的破坏在叶片中比在根部更为强烈。 | Edwards, J. | PDF | N/A | Warming disrupts plant-fungal endophyte symbiosis more strongly in leaves than roots | | 在脆性X综合征小鼠模型中,AM6545治疗的促认知作用涉及一种血清素能机制。 | de los Reyes-Ramirez, L. | PDF | N/A | A serotonergic mechanism is involved in the pro-cognitive effect of AM6545 treatment in a mouse model of fragile X syndrome | | 三种鱼类侧线在群体行为中的不同功能 | Tidswell, B. K. | PDF | N/A | Different functions for the lateral line in schooling behavior in three fish species | | 运动路径作为研究间隔时间的动物行为学视角 | Balci, F. | PDF | N/A | Movement path as an ethological lens into interval timing | | 通过强化学习模型在强迫游泳试验(FST)和尾悬试验(TST)中揭示小鼠的认知过程 | Li, Z. | PDF | N/A | Unveiling Cognitive Processes in Mice through Reinforcement Learning Models in the FST and TST | | BuzzWatch:通过持续长期监测揭示蚊子行为的多尺度时间模式 | Maire, T. | PDF | N/A | BuzzWatch: uncovering multi-scale temporal patterns in mosquito behavior through continuous long-term monitoring | | 龟类的跨模态音高-亮度关联 | Loconsole, M. | PDF | N/A | Crossmodal pitch-luminance association in tortoises | | 对大鼠进行饮食蛋白质限制会导致其在短时间内迅速偏好蛋白质。 | Chiacchierini, G. | PDF | N/A | Dietary protein restriction in rats leads to a rapid within-session preference for protein | | 不同的人工照明光谱改变了多食性捕食者Orius insidiosus(Say)的交配行为,而光周期延长则促进了其发育。 | Canovas, M. L. | PDF | N/A | Different artificial lighting spectra change the mating behavior of generalist predator Orius insidiosus (Say), and photoperiod extension promotes its development | | 快速转弯不会加速慢速转弯:蓝鳃太阳鱼如何随转弯速度改变其运动学 | Clark, A. D. | PDF | N/A | Fast turns are not sped up slow turns: How bluegill sunfish change their kinematics with turn speed | | ChemBERTaDDI:利用Transformer模型和临床洞察革新药物相互作用预测 | Gromova, A. A. | PDF | N/A | ChemBERTaDDI: Transforming Drug-Drug Interaction Prediction with Transformers and Clinical Insights | | StrPhaser从VCF数据中构建串联重复等位基因。 | Wang, X. | PDF | N/A | StrPhaser constructs tandem repeat alleles from VCF data | | 为mx-plore平台挖掘miRNA-基因相互作用的文本挖掘 | Joppich, M. | PDF | N/A | Text Mining miRNA-gene Interactions for the mx-plore Platform | | SqueezeCall:使用Squeezeformer网络进行纳米孔测序的碱基识别 | Zhu, Z. | PDF | N/A | SqueezeCall: Nanopore basecalling using a Squeezeformer network | | 配体结合对2型血管紧张素II受体激活的影响 | YASAR, E. | PDF | N/A | Ligand Binding Effects on Activation of Type-2 Angiotensin II Receptor | | WNT介导的肠上皮转化过程中基质Pdgfra表达细胞的动态重编程 | Pellon-Cardenas, O. | PDF | N/A | Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium | | 通过定量免疫组化(IHC)和人工智能技术对乳腺癌标本中HER2低表达和超低表达进行量化分析 | Aidt, F. | PDF | N/A | Quantification of HER2-low and ultra-low expression in breast cancer specimens by quantitative IHC and artificial intelligence | | 双过程模型:从数学角度来看,它是简单、复杂还是独特的? | Skeldon, A. C. | PDF | N/A | The two-process model: How simple, complex, unique is it from a mathematical perspective? | | 在阿尔茨海默病的淀粉样蛋白小鼠模型中,星形胶质细胞终足与邻近脑小动脉之间的信号传递保真度丧失。 | Weiss, B. E. | PDF | N/A | Loss of signaling fidelity between astrocyte endfeet and adjacent cerebral arterioles in an amyloid mouse model of Alzheimer's disease | | 单个多巴胺能神经元能够引发独特但部分重叠的行为调节组合,这些调节包括安全学习、记忆检索和急性运动。 | Toshima, N. | PDF | N/A | Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotion | | 以下是这段英文的中文翻译:

甲磺酸去铁胺在含血清和无血清培养基中的功效:过氧化氢诱导细胞死亡后成年雪旺细胞的存活

翻译说明: - Efficacy 翻译为“功效”或“有效性”。 - Deferoxamine Mesylate 是药物名称,翻译为“甲磺酸去铁胺”。 - Serum and Serum-Free Media 翻译为“含血清和无血清培养基”。 - Adult Schwann Cell 翻译为“成年雪旺细胞”。 - Hydrogen Peroxide Induced Cell Death 翻译为“过氧化氢诱导的细胞死亡”。

希望这段翻译对你有帮助! | Ma, Y. H. E. | PDF | N/A | Efficacy of Deferoxamine Mesylate in Serum and Serum-Free Media: Adult Schwann Cell Survival Following Hydrogen Peroxide Induced Cell Death | | 在阿尔茨海默病的AppNL-G-F敲入小鼠模型中,记忆修改的错误分类 | Huang, M.-L. | PDF | N/A | Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimers disease | | 操作性住宅:一种多功能开源平台,用于在家庭笼中进行小鼠自动化操作性条件测试 | Otsuka, S. | PDF | N/A | Operant House: A Versatile Open-Source Platform for Automated Operant Conditioning Testing of Mice in Home Cages | | 平衡整合与分离:结构连接性作为脑网络动态的驱动力 | Palma-Espinosa, J. | PDF | N/A | Balancing Integration and Segregation: StructuralConnectivity as a Driver of Brain Network Dynamics | | 突触磷酸化蛋白质组的改变与皮质回路功能障碍与α-突触核蛋白聚集的早期进展相关。 | Dutta, S. | PDF | N/A | Synaptic phosphoproteome modifications and cortical circuit dysfunction are linked to the early-stage progression of alpha-synuclein aggregation | | 单细胞研究方法揭示了小鼠软脑膜-皮层脑界面作为一个独特的细胞微环境,由神经细胞和非神经细胞类型共同构成。 | Ebert, S. N. | PDF | N/A | Single cell approaches define the murine leptomeninges:cortical brain interface as a distinct cellular neighborhood comprised of neural and nonneural cell types | | CalciumNetExploreR:一个用于钙成像数据网络分析的R包 | Lenci, S. | PDF | N/A | CalciumNetExploreR: An R Package for Network Analysis of Calcium Imaging Data | | 神经活性类固醇通过激活膜孕酮受体,对蛋白激酶活性产生性别特异性影响。 | Lemons, A. H. | PDF | N/A | Neuroactive steroids activate membrane progesterone receptors to induce sex specific effects on protein kinase activity | | 基于成就的课堂学习中认知-情感互动的差异:采用经验抽样法的多模态分析 | Liu, X. | PDF | N/A | Achievement-Based Differences in Cognitive-Emotional Interplay During Classroom Learning: A Multimodal Analysis with Experience Sampling Method | | 碳酸酐酶4的破坏和药理抑制减少了羟考酮戒断后的突触和行为适应。 | Gupta, S. C. | PDF | N/A | Carbonic anhydrase 4 disruption and pharmacological inhibition reduce synaptic and behavioral adaptations following oxycodone withdrawal | | 运动皮层回路受到不同运动强度的独特影响 | Harroum, N. | PDF | N/A | Motor cortical circuits are uniquely impacted by different exercise intensities | | 转甲状腺素蛋白水平与阿尔茨海默病的不稳定性:一项队列研究中与AD生物标志物的相关性

在这项研究中,我们探讨了转甲状腺素蛋白(Transthyretin, TTR)水平及其不稳定性与阿尔茨海默病(Alzheimer's Disease, AD)之间的关系。通过对一组患者进行队列研究,我们分析了TTR水平与AD相关生物标志物之间的相关性。研究结果表明,TTR水平的变化可能与AD的病理过程有关,并且这些变化与已知的AD生物标志物存在一定的关联。这一发现为进一步理解AD的发病机制提供了新的视角,并可能为未来的诊断和治疗策略提供潜在的生物标志物。 | Giao, T. | PDF | N/A | Transthyretin Levels and Instability in Alzheimer's Disease: Correlations with AD Biomarkers in a Cohort Study | | 对努力程度的知识调节了对身体姿势的视觉记忆偏差 | Han, Q. | PDF | N/A | Knowledge of effort modulates visual memory biases for body postures | | 人类场景选择性皮层中全景和基于地标的视图整合的独特机制 | Han, L. T. | PDF | N/A | Distinct mechanisms for panoramic and landmark-based view integration in human scene-selective cortex | | 决策的神经状态空间的几何结构 | Monsalve-Mercado, M. M. | PDF | N/A | The geometry of the neural state space of decisions | | 图像偏移集的同步置信区域:一项验证研究及其在功能磁共振成像中的应用 | qin, j. | PDF | N/A | Simultaneous Confidence Regions for Image Excursion Sets: a Validation Study with Applications in fMRI | | 在早期年龄相关性黄斑变性中,减弱的腺苷介导的免疫抑制作用增加了自然杀伤细胞的活性。 | Nair, A. P. | PDF | N/A | Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degeneration | | TRAIL介导的PMN-MDSC耗竭可防止HIV感染的人源化小鼠中CD4+ T细胞的丢失 | Paust, S. | PDF | N/A | TRAIL-mediated PMN-MDSC depletion prevents CD4+ T cell loss in HIV-infectedhumanized mice | | Toti:一个集成的多组学数据库,用于解读全能干细胞中基因表达的表观遗传调控 | Chai, Y. | PDF | N/A | Toti: an integrated multi-omics database to decipher the epigenetic regulation of gene expression in totipotent stem cells | | VPS13D基因突变会破坏线虫(Caenorhabditis elegans)的线粒体稳态和运动能力。 | Alkema, M. J. | PDF | N/A | VPS13D mutations disrupt mitochondrial homeostasis and locomotion in Caenorhabditis elegans | | ST-FFPE-mIF: 使用Stereo-seq技术整合空间转录组学和多重免疫荧光在福尔马林固定石蜡包埋组织中的应用 | Zhang, X. | PDF | N/A | ST-FFPE-mIF: Integrating Spatial Transcriptomics and Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tissues Using Stereo-seq | | Lambda N作为研究大肠杆菌ATP依赖性蛋白酶Lon作为调节酶机制的模型底物。 | Castro, M. | PDF | N/A | Lambda N as a model substrate for studying the mechanism of Escherichia coli ATP-dependent protease Lon as a regulatory enzyme. | | 在棒状细菌生长的菌落中,细胞形状引发的自发空间排序 | Ratman, M. | PDF | N/A | Spontaneous spatial sorting by cell shape in growing colonies of rod-like bacteria | | 通过蛋白质凝聚体引起的毛细作用导致生物聚合物网络的成束现象 | Feigeles, C. A. | PDF | N/A | Capillary-induced bundling of biopolymer networks via protein condensates | | 质粒拷贝数变异影响病原性及感染绿豆的黄色镰孢菌(Curtobacterium flaccumfaciens pv. flaccumfaciens)的定量分析。 | Saad, A. | PDF | N/A | Plasmid copy number variation impacts pathogenicity and quantification of Curtobacterium flaccumfaciens pv. flaccumfaciens infecting mung bean | | 饮食蛋白质来源通过细菌对胆汁酸的调节介导结肠炎发病机制 | Gray, S. M. | PDF | N/A | Dietary protein source mediates colitis pathogenesis through bacterial modulation of bile acids | | 定制女性卫生洗液,含有来自乳酸菌属的后生元,用于治疗尿路感染(UTI)。 | Nair, V. G. | PDF | N/A | Customized feminine hygiene wash containing postbiotics from Lactobacillus spp. to treat Urinary Tract Infections (UTI) | | 高温胁迫下拟南芥品系中短串联重复序列突变的高复发率 | Reinar, W. B. | PDF | N/A | High short tandem repeat mutation recurrence in heat-stressed Arabidopsis thaliana lines | | 在小鼠中减少Glo1的表达会导致年龄和性别依赖性的代谢功能障碍。 | Cely, I. | PDF | N/A | Glo1 reduction in mice results in age- and sex-dependent metabolic dysfunction | | IS91编码的Orf121在IS91转座中的双重调控作用 | Fauconnier, A. | PDF | N/A | Dual regulatory role of IS91-encoded Orf121 in IS91 transposition | | 空间明确的捕获-再捕获模型用于相对密度 | Efford, M. G. | PDF | N/A | Spatially explicit capture-recapture models for relative density | | 以下是这段英文的中文翻译:

来自秘鲁北部的Anadenanthera colubrina的体外抗氧化和抗炎活性、总酚和类黄酮含量

翻译说明: - In vitro:体外(指在实验室条件下进行的实验) - antioxidant:抗氧化 - anti-inflammatory:抗炎 - total phenolic:总酚 - flavonoid contents:类黄酮含量 - Anadenanthera colubrina:一种植物名称,通常不翻译,保留拉丁学名 - Northern Peru:秘鲁北部

希望这个翻译对你有帮助! | Samame-Caramutti, E. A. | PDF | N/A | In vitro antioxidant and anti-inflammatory activities, total phenolic and flavonoid contents of Anadenanthera colubrina from Northern Peru | | MitoEdit:一个用于优化线粒体DNA(mtDNA)碱基编辑并预测旁观者效应的流程 | Shah, D. | PDF | N/A | MitoEdit: a pipeline for optimizing mtDNA base editing and predicting bystander effects | | SMTdb:一个全面的癌症空间元转录组资源数据库 | Yongsheng, L. | PDF | N/A | SMTdb: A comprehensive spatial meta-transcriptome resource in cancer | | FlashFold:一款独立的命令行工具,用于加速蛋白质结构预测 | Saha, C. K. | PDF | N/A | FlashFold: a standalone command-line tool for accelerated protein structure prediction | | 一种新型DNA修复蛋白,N-Myc下游调控基因1(NDRG1),将基质肿瘤微环境与化疗耐药性联系起来 | Kozlova, N. | PDF | N/A | A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance | | 神经干细胞和胶质瘤干细胞中静止状态的共享分子调控揭示了治疗上的脆弱性。 | Choudhury, C. | PDF | N/A | Shared molecular regulation of quiescence in neural and glioma stem cells reveals therapeutic vulnerabilities. | | Eg5抑制剂SB743921在肿瘤细胞中引起p53依赖的细胞周期阻滞、衰老和死亡 | Abramenko, I. E. | PDF | N/A | Eg5 Inhibitor SB743921 Causes p53-Dependent Cell Cycle Arrest, Senescence and Death in Tumor Cells | | 模拟放疗对癌症干细胞演化的影响 | Heryanto, Y. D. | PDF | N/A | Simulating The Effect of the Radiotherapy on Cancer Stem Cell Evolution | | 深度学习驱动的形态学分析实现了对未经治疗与耐药癌细胞的无需标记分类。 | Ramathal, C. | PDF | N/A | Deep learning-driven morphology analysis enables label-free classification of therapeutic agent- naive versus resistant cancer cells | | 优化用于常用的小鼠保留射血分数心力衰竭模型的实验方案。 | McIntosh, B. | PDF | N/A | Optimized protocols for commonly-used murine models of heart failure with preserved ejection fraction. | | 在属间酵母之间转移功能性染色体可以产生具有改进表型和转录反应的单染色体杂合体。 | Lyu, Y. | PDF | N/A | Transferring functional chromosomes between intergeneric yeast generates monochromosomal hybrids with improved phenotypes and transcriptional responses | | 无细胞蛋白质合成作为一种快速筛选机器学习指导的蛋白酶变体的方法 | Thornton, E. L. | PDF | N/A | Cell-free protein synthesis as a method to rapidly screen machine learning-directed protease variants | | LubriShieldTM - 一种独特的永久性涂层,用于留置导尿管,能够阻止表面相关的尿路病原体形成生物膜。 | Romero, A. I. | PDF | N/A | LubriShieldTM - a unique permanent coating for indwelling urinary catheters that impedes surface-associated uropathogens from forming biofilm | | 小麦感染禾谷镰刀菌复合体成员的过程,受到一个在转录上保守的非核糖体肽合成酶基因簇的促进。 | Tralamazza, S. M. | PDF | N/A | Wheat infection by Fusarium graminearum species complex members is facilitated by a transcriptionally conserved non-ribosomal peptide synthetase gene cluster | | 探索源自卷柏属植物Selaginella bryopteris的银纳米颗粒的抗癌活性 | Dutta, A. | PDF | N/A | Exploration of the Anticancer Activity of Selaginella bryopteris-derived Silver Nanoparticles | | 在体外合成未修饰的超螺旋环状DNA分子 | Rezaei, S. | PDF | N/A | Synthesizing unmodified, supercoiled circular DNA molecules in vitro | | UNICORN:迈向通用细胞表达预测的可解释多任务学习框架 | Liu, T. | PDF | N/A | UNICORN: Towards Universal Cellular Expression Prediction with an Explainable Multi-Task Learning Framework | | 低场磁共振成像检测急性肾损伤 | Kishimoto, S. | PDF | N/A | Low Field Magnetic Resonance Imaging to Detect Acute Kidney Injury |

medRxiv

标题 作者 PDF链接 代码仓库 Title
亚太地区体重指数分类与非糖尿病日本成年人新发慢性肾脏病的关系:1998年至2023年基于社区的纵向研究 Okawa, Y. PDF N/A The Asia-Pacific body mass index classification and new-onset chronic kidney disease in non-diabetic Japanese adults: A community-based longitudinal study from 1998 to 2023
远程监测植入式心脏复律除颤器或心脏再同步治疗除颤器的各个组成部分的效果:系统评价和组成部分网络荟萃分析方案

这段文字描述了一项研究计划,旨在通过系统评价和网络荟萃分析的方法,评估远程监测技术在植入式心脏复律除颤器(ICD)或心脏再同步治疗除颤器(CRT-D)中各个组成部分的效果。研究将遵循预先制定的方案,以确保分析的全面性和科学性。 | Okazaki, M. | PDF | N/A | Effects of individual components of remote monitoring for implantable cardioverter defibrillators or cardiac resynchronisation therapy defibrillators: protocol for a systematic review and component network meta-analysis | | 简化GWAS位点中因果基因的识别 | Schipper, M. | PDF | N/A | Simplifying causal gene identification in GWAS loci | | 高频重复经颅磁刺激对脑卒中后上肢功能的影响:系统综述与荟萃分析 | Russo, N. | PDF | N/A | Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on Upper Limb Function After Stroke: A Systematic Review and Meta-Analysis | | 与高水平尼古丁代谢物可替宁相关的人体死后额叶皮层和脑脊液中的代谢变化 | Masvosva, W. | PDF | N/A | Metabolic alterations in human post-mortem frontal cortex and cerebrospinal fluid associated with high levels of nicotine metabolite cotinine | | 基于结构化模拟训练和简易眼科仪器,迅速使非眼科医生能够识别疟疾性视网膜病变。 | Wilson, K. J. | PDF | N/A | Structured simulation-based training with frugal ophthalmic instruments rapidly equips non-ophthalmologists to identify malarial retinopathy | | 针对65岁时阿尔茨海默病、帕金森病及痴呆症的2年、5年和10年风险预测的机器学习算法研究:一项基于法国和英国全科医生医疗记录的分析 | Nedelec, T. | PDF | N/A | Machine learning prediction algorithms for 2- , 5- and 10-year risk of Alzheimer's, Parkinson's and dementia at age 65: a study using medical records from France and the UK General Practitioners | | 杏仁核和额叶皮层的脂肪变性:阿尔茨海默病的潜在磁共振成像生物标志物

摘要
阿尔茨海默病(AD)是一种神经退行性疾病,其特征是认知功能逐渐下降和大脑病理改变。近年来,研究发现脂肪变性(steatosis)在AD的病理过程中可能扮演重要角色。本文探讨了杏仁核和额叶皮层中的脂肪变性作为AD潜在磁共振成像(MRI)生物标志物的可能性。通过分析现有的研究数据,我们发现这些区域的脂肪变性可能与AD的早期病理变化相关,并可能成为未来诊断和监测AD的重要工具。本文还讨论了脂肪变性与AD病理机制之间的潜在联系,以及未来研究的方向。

关键词
阿尔茨海默病,脂肪变性,杏仁核,额叶皮层,磁共振成像,生物标志物 | de Oliveira Andrade, L. J. | PDF | N/A | Steatosis in the Amygdala and Frontal Cortex: Potential Magnetic Resonance Imaging Biomarkers for Alzheimer's Disease | | 印度母子对贫血状况:趋势、驱动因素及未来预测

该翻译将原文标题“Anaemia among mother-child dyads in India: trends, drivers, and future projections”转换为中文,同时保持了原文的专业性和准确性。翻译后的标题“印度母子对贫血状况:趋势、驱动因素及未来预测”清晰地传达了研究的核心内容,即关注印度母亲与孩子这一特定群体中贫血的现状、影响因素以及未来的发展趋势。这样的翻译既符合中文表达习惯,又确保了信息的完整传递。 | Pedgaonkar, S. | PDF | N/A | Anaemia among mother-child dyads in India: trends, drivers, and future projections | | 基于基础模型的多实例学习对头颈部鳞状细胞癌临床结果的端到端预测 | Rabasco Meneghetti, A. | PDF | N/A | End-to-end prediction of clinical outcomes in head and neck squamous cell carcinoma with foundation model-based multiple instance learning | | 多基因评分在前列腺癌侵袭性中的特异性 | Dornisch, A. | PDF | N/A | Specificity of a polygenic score for aggressive prostate cancer | | 《拔毛癖的基因组分析》 | Halvorsen, M. W. | PDF | N/A | Genomic Analysis of Trichotillomania | | 一项关于接受免疫检查点抑制剂治疗患者免疫相关不良事件的真实世界队列研究 | Wang, Y. | PDF | N/A | A real-world cohort study of immune-related adverse events in patients receiving immune checkpoint inhibitors | | 测量衰弱:调查数据与常规数据中累积缺陷模型的比较 | Johnson, L. | PDF | N/A | Measuring Frailty: A Comparison of the Cumulative Deficit Model of Frailty in Survey and Routine Data | | 腹泻的成本:来自全球肠道多中心研究(GEMS)七个国家的家庭视角 | Al Fidah, M. F. | PDF | N/A | The cost of diarrhoea: a household perspective from seven countries in the Global Enteric Multicenter Study (GEMS) | | TICTAC:结合化学信息学的目标照明临床试验分析 | Abok, J. I. | PDF | N/A | TICTAC: Target Illumination Clinical Trial Analytics with Cheminformatics | | 创建一个基于多项临床研究的医疗数据通用生成模型 | Maruyama, H. | PDF | N/A | Creating a General-Purpose Generative Model for Healthcare Data based on Multiple Clinical Studies | | 全球医疗保健领域的人工智能监管:现状如何? | Busch, F. | PDF | N/A | AI regulation in healthcare around the world: what is the status quo? | | 评估从英国市场上四种侧流设备产品中恢复SARS-CoV2基因组序列的能力。 | Lewandowski, K. | PDF | N/A | Assessment of SARS-CoV2 genome sequence recovery from four lateral flow device products available in the UK. | | 废水综合病原体监测仪表板能够实现实时、透明且易于理解的公共卫生风险评估与信息传播。 | Msomi, N. S. | PDF | N/A | Wastewater-integrated pathogen surveillance dashboards enable real-time, transparent, and interpretable public health risk assessment and dissemination | | 在避难所环境中进行的新冠病毒快速抗原检测的准确性 | Garad, Y. | PDF | N/A | Accuracy of rapid antigen testing for COVID-19 in shelter settings | | 高PEEP策略对急性呼吸窘迫综合征生存率的异质性影响:随机试验数据驱动分析的初步结果 | Smit, J. M. | PDF | N/A | The Heterogeneous Effect of High PEEP strategies on Survival in Acute Respiratory Distress Syndrome: preliminary results of a data-driven analysis of randomized trials | | 血浆蛋白质在基因调控网络中起着至关重要的作用,这些网络在血细胞内部和之间、动脉壁以及主要代谢器官中发挥作用。 | Bankier, S. | PDF | N/A | Plasma proteins are integral to gene-regulatory networks acting within and across blood cells, the arterial wall and major metabolic organs | | 了解他汀类药物依从性低的原因和后果:来自英国生物银行初级保健数据的证据 | Türkmen, D. | PDF | N/A | Understanding the causes and consequences of low statin adherence: evidence from UK Biobank primary care data | | 使用现代最优收缩技术从皮肤记录中恢复交感神经活动 | Su, P.-C. | PDF | N/A | Sympathetic nerve activity recovery from the skin recording using the modern optimal shrinkage technique | | 移民如何影响加拿大外籍人口中结核病的负担:基于动态模型的估计 | Chiu, J. | PDF | N/A | How immigration affects the burden of tuberculosis among foreign-born Canadians: estimates with dynamic models | | 提高英国布里斯托尔住院成人中呼吸道合胞病毒(RSV)发病率的准确性 | Lihou, K. | PDF | N/A | Improving the accuracy of Respiratory Syncytial Virus (RSV) incidence among hospitalised adults in Bristol, UK | | 降压药物对青光眼的影响:孟德尔随机化与三角分析研究 | Huang, Y. | PDF | N/A | Effect of antihypertensive drugs on glaucoma: a Mendelian randomization and triangulation analysis | | 比较Esri ArcGIS与SAS地理编码方法:以3,238个威斯康星州地址为测试案例 | Johnson, H. K. | PDF | N/A | Comparing Esri ArcGIS and SAS Geocoding Approaches: Test case with 3,238 Wisconsin addresses | | COVID-19非药物干预效果的不确定性与不一致性:基于多种竞争性统计模型的分析 | Mueller, B. | PDF | N/A | Uncertainty and Inconsistency of COVID-19 Non-Pharmaceutical Intervention Effects with Multiple Competitive Statistical Models | | 网络荟萃分析结合生存和计数结果数据:一种简单的频率学方法 | Noma, H. | PDF | N/A | Network meta-analysis combining survival and count outcome data: A simple frequentist approach | | 南非出生队列中母亲和婴儿的铁缺乏性贫血:在炎症背景下的患病率和特征 | Ringshaw, J. E. | PDF | N/A | Iron Deficiency Anaemia in Mothers and Infants from a South African Birth Cohort: Prevalence and Profile in the Context of Inflammation | | 儿童用药自我效能量表的开发与验证 | Yu, z. | PDF | N/A | Development and Validation of the Children's Medication Self-Efficacy Scale | | 影响2型糖尿病一线治疗处方的因素:系统综述 | Moreira, H. R. S. D. | PDF | N/A | Factors influencing the prescription of first-line treatment for type 2 diabetes mellitus: a systematic review | | 以下是将这段英文翻译成中文的结果:

一项系统文献综述:比较面对面和数字化干预措施在2型糖尿病预防中的随机试验。

翻译说明: 1. Systematic Literature Review 翻译为“系统文献综述”,这是一种系统性的研究方法,用于全面收集和分析某一主题的相关文献。 2. Randomized Trials 翻译为“随机试验”,指的是采用随机分组方法的临床试验。 3. In-Person and Digital Interventions 翻译为“面对面和数字化干预措施”,分别指传统的面对面干预和基于数字技术的干预方式。 4. Type 2 Diabetes Prevention 翻译为“2型糖尿病预防”,指的是针对2型糖尿病的预防措施。

希望这个翻译对你有帮助!如果有其他问题,欢迎随时提问。 | Riera-Serra, P. | PDF | N/A | A Systematic Literature Review of Randomized Trials Comparing In-Person and Digital Interventions for Type 2 Diabetes Prevention. | | 暴饮暴食与心理困扰:探讨其与抑郁、焦虑和压力的关系 | Soares Marinho, A. C. | PDF | N/A | Binge Eating and Psychological Distress: Investigating Relationships with Depression, Anxiety, and Stress | | 非自杀性自伤功能的神经相关性:精神疾病中的神经生物学脆弱性与心理社会风险 | Li, M. | PDF | N/A | Neural Correlates of Non-Suicidal Self-Injury Functions: Neurobiological Vulnerabilities and Psychosocial Risks in Psychiatric Disorders | | 2022年,孕妇向澳大利亚免疫登记处报告流感和百日咳疫苗接种情况的模式 | Sonneveld, N. | PDF | N/A | Patterns of reporting of influenza and pertussis vaccination during pregnancy to the Australian Immunisation Register, 2022 | | 在接触ChatGPT后,公众对医疗领域人工智能的看法发生了变化。 | Isaksen, A. A. | PDF | N/A | Changes in public perception of AI in healthcare after exposure to ChatGPT | | 如果我们能够及早处理,我们就能做对:肯尼亚一家转诊医院医护人员处理败血症的经验 | Srour, M. | PDF | N/A | If we manage early, we can get it right: Healthcare Workers Experiences Managing Sepsis at a Kenyan Referral Hospital | | 功能性连接磁共振成像数据在病灶性和非病灶性脑疾病中的去噪策略 | Wunderlich, S. | PDF | N/A | Denoising Strategies of Functional Connectivity MRI Data in Lesional and Non-Lesional Brain Diseases | | 利用手工制作的放射组学特征在多中心FLAIR MRI上预测多发性硬化症患者的残疾进展 | Khan, H. | PDF | N/A | Leveraging Hand-Crafted Radiomics on Multicenter FLAIR MRI for Predicting Disability Progression in People with Multiple Sclerosis | | 将肥胖相关特征与区域白质微结构进行映射,突显了脑干束的重要性以及性别相关的差异。 | Gurholt, T. P. | PDF | N/A | Mapping obesity-related traits with regional white matter microstructure highlights the importance of brainstem tracts and sex-related differences. | | 趋近-回避倾向影响骨关节炎患者对运动的恐惧与身体活动之间的关系 | Goubran, M. | PDF | N/A | Approach-avoidance tendencies influence the relationship between fear of movement and physical activity in osteoarthritis | | 长期氧疗的慢性阻塞性肺疾病(COPD)患者在家中使用自动氧气输送的随机交叉可行性试验 | Kofod, L. M. | PDF | N/A | Automated Oxygen Delivery in Home Setting for Patients with COPD on Long-Term Oxygen Therapy - a randomized crossover feasibility trial | | 使用便携式脑电图(EEG)进行的多晚家庭睡眠测试显示,开始使用持续气道正压通气(CPAP)治疗阻塞性睡眠呼吸暂停后,睡眠质量有所改善。 | Lee, K. O. | PDF | N/A | Multi-Night Home testing with portable EEG shows Improvement in Sleep Quality after Starting CPAP for Obstructive Sleep Apnoea | | 激活素A通过激活ALK4诱导致病性Th17细胞参与系统性红斑狼疮相关肺动脉高压中的内皮间质转化。 | Jing, S. | PDF | N/A | Activin A activated ALK4 induces pathogenic Th17 involvement in endothelial mesenchymal transition in systemic lupus erythematosus associated pulmonary arterial hypertension | | 医学妇科专业高级阶段(DES)实习生对医学论文的现状与期望。 | Poisson, A. | PDF | N/A | State of affairs and expectations of medical interns in the advanced phase of the DES (specialized medical studies) in medical gynecology regarding medical theses. | | 现实世界中的智能手机数据能够预测脑血管症状后的情绪状态,并可能构成数字终点。 | Zawada, S. J. | PDF | N/A | Real-world smartphone data predicts mood after cerebrovascular symptoms and may constitute digital endpoints | | 神经科医生是否该在日常实践中使用大型语言模型了? | Maiorana, N. V. | PDF | N/A | Is it time for the neurologist to use Large Language Models in everyday practice? | | 以下是这段英文的中文翻译:

"左额顶叶网络伽马频段经颅交流电刺激引起的神经变化:一项初步的eLORETA脑电图研究"

解释: - "Neural changes" 翻译为 "神经变化" - "transcranial alternating current stimulation" 翻译为 "经颅交流电刺激" - "gamma range" 翻译为 "伽马频段" - "left frontoparietal network" 翻译为 "左额顶叶网络" - "preliminary" 翻译为 "初步的" - "eLORETA EEG study" 翻译为 "eLORETA脑电图研究"

这个标题描述了一项使用eLORETA脑电图技术来研究伽马频段经颅交流电刺激对左额顶叶网络神经活动影响的初步研究。 | Lee, T.-W. | PDF | N/A | Neural changes to transcranial alternating current stimulation in the gamma range over the left frontoparietal network: a preliminary eLORETA EEG study | | 颅内光生物调节治疗新诊断帕金森病患者:一项正在进行中的随机对照试验的初步数据。 | Chabardes, S. | PDF | N/A | Intracranial photobiomodulation in de novo PD patients: preliminary data of an ongoing randomized controlled trial. | | 优化癫痫患者前丘脑核深部脑刺激的刺激参数:一项随机交叉试验 | Alcala Zermeno, J. L. | PDF | N/A | Optimizing stimulation parameters for anterior thalamic nuclei deep brain stimulation in epilepsy: A randomized cross-over trial | | 脐带血神经丝轻链与非安心胎儿状态的相关性:一项前瞻性观察研究 | Zalcberg, D. | PDF | N/A | The association of umbilical cord blood neurofilament light with non-reassuring fetal status: a prospective observational study | | 泰国无家可归者工作表现评估的已知群体效度 | Thanapet, U. | PDF | N/A | Known Group Validity of Assessment of Work Performance for Thai Homeless People | | 神经元外泌体的分子特征分析揭示了脑组织特异性信号 | Kalia, V. | PDF | N/A | Molecular profiling of neuronal extracellular vesicles reveals brain tissue specific signals | | FITM2功能的部分丧失会导致遗传性痉挛性截瘫。 | Salazar-Villacorta, A. | PDF | N/A | Partial loss of FITM2 function causes hereditary spastic paraplegia | | 基于患者特征与伤口微生物组构成的结构方程模型预测慢性伤口愈合时间 | Ancira, J. | PDF | N/A | A STRUCTURAL EQUATION MODEL PREDICTS CHRONIC WOUND HEALING TIME USING PATIENT CHARACTERISTICS AND WOUND MICROBIOME COMPOSITION |