2025-02-03 每日论文

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arXiv	arXiv
bioRxiv	bioRxiv
medRxiv	medRxiv

arXiv

标题	作者	PDF链接	代码仓库	Title

bioRxiv

标题	作者	PDF链接	代码仓库	Title
潜适应病毒中的叛离细菌基因序列：生物学与诊断意义	Martin, W. J.	PDF	N/A	Renegade Bacterial Genetic Sequences in a Stealth Adapted Virus: Biological and Diagnostic Implications
基于qpAdm的遗传混合筛选在混合图历史形态和踏脚石景观中的表现	Flegontova, O.	PDF	N/A	Performance of qpAdm-based screens for genetic admixture on admixture-graph-shaped histories and stepping-stone landscapes
老年PANX3基因敲除小鼠中的严重骨关节炎：新型原发性骨关节炎模型的启示

基因组数据分析和BA.1 SARS-CoV-2刺突蛋白缺失修复的功能研究

翻译说明： - "Genome data artifacts" 翻译为“基因组数据分析”，指的是对基因组数据的处理和研究。 - "functional studies" 翻译为“功能研究”，指的是对基因或蛋白质功能的实验研究。 - "deletion repair" 翻译为“缺失修复”，指的是对基因或蛋白质中缺失部分的修复机制研究。 - "BA.1 SARS-CoV-2 spike protein" 翻译为“BA.1 SARS-CoV-2刺突蛋白”，指的是新冠病毒BA.1变种的刺突蛋白。

促进斯氏按蚊（Anopheles stephensi）吸血行为的两种神经肽

翻译说明： 1. "Two neuropeptides" 翻译为 "两种神经肽" 2. "that promote blood-feeding" 翻译为 "促进吸血行为的" 3. "Anopheles stephensi mosquitoes" 翻译为 "斯氏按蚊" 4. 按照中文表达习惯，将修饰成分前置，整合为"促进斯氏按蚊（Anopheles stephensi）吸血行为的两种神经肽" 5. 保留了英文学名"Anopheles stephensi"并用括号标注，符合学术文献的翻译规范

这个翻译准确传达了原文的科学含义，同时符合中文表达习惯和学术翻译规范。 | Bansal, P. | PDF | N/A | Two neuropeptides that promote blood-feeding in Anopheles stephensi mosquitoes | | Mia40底物Mix17将其N端暴露于线粒体外膜的胞质侧。 | Resch, M. | PDF | N/A | The Mia40 substrate Mix17 exposes its N-terminus to the cytosolic side of the mitochondrial outer membrane | | Reuniens丘脑募集内侧前额叶皮层的重复性兴奋。 | Vantomme, G. | PDF | N/A | Reuniens thalamus recruits recurrent excitation in medial prefrontal cortex. | | 一种用于再生医学的化学定义且无异种成分的水凝胶系统。 | Ong, J. | PDF | N/A | A chemically defined and xeno-free hydrogel system for regenerative medicine. | | 布罗科小体作为叶蝉的抗反射伪装涂层 | wu, w. | PDF | N/A | Brochosomes as an antireflective camouflage coating for leafhoppers | | 冷冻电子显微镜与质谱联用进行同步多克隆抗体测序和表位定位——一种视角。 | Schulte, D. | PDF | N/A | Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry - a perspective. | | 使用Metient推断癌症类型特异性转移扩散模式 | Koyyalagunta, D. | PDF | N/A | Inferring cancer type-specific patterns of metastatic spread using Metient | | 以下是这段文字的中文翻译：

NHLBI跨组学精准医学（TOPMed）计划中循环代谢物的遗传结构和分析实践

翻译说明： - "Genetic Architecture" 翻译为 "遗传结构"，指的是基因与表型之间的复杂关系。 - "Circulating Metabolites" 翻译为 "循环代谢物"，指的是在血液或其他体液中循环的小分子代谢产物。 - "NHLBI" 是美国国家心肺血液研究所的缩写，通常保留英文缩写。 - "Trans-Omics for Precision Medicine (TOPMed)" 翻译为 "跨组学精准医学（TOPMed）"，指的是通过整合多种组学数据（如基因组学、代谢组学等）来实现精准医学的目标。

希望这个翻译对你有帮助！如果有其他问题，欢迎继续提问。 | Wang, N. | PDF | N/A | Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program | | 玫瑰即使换了名字：迈向神经免疫相互作用中记忆的定量理论 | Fadai, N. T. | PDF | N/A | A Rose by any Other Name: Towards a quantitative theory of memory in neuroimmune interactions | | 增殖停滞诱导了对照组和克雅氏病病原体（CJ）感染的大鼠隔区神经元的神经元分化和先天免疫反应。 | pagano, n. | PDF | N/A | Proliferative arrest induces neuron differentiation and innate immune responses in control and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons | | HLA多态性影响对APOBEC突变癌症中新抗原的免疫反应及生存率 | Borzooee, F. | PDF | N/A | HLA polymorphism impacts immune response to neoepitopes and survival in APOBEC-mutated cancers | | 目标性时变功能连接 | Alonso, S. | PDF | N/A | Targeted Time-Varying Functional Connectivity | | 放牧生境中，本地筑巢资源而非花卉食物改变了地面筑巢蜂群落。 | Collins, S. M. | PDF | N/A | Local nesting resources rather than floral food alter ground-nesting bee communities in grazed habitats | | 深度麻醉状态下脑状态的图模型揭示了时空复杂性降低的汇状态动态 | Wilsenach, J. | PDF | N/A | Graph models of brain state in deep anaesthesia reveal sink state dynamics of reduced spatiotemporal complexity | | 丙型肝炎病毒感染中病毒适应性及适应性免疫应答的时间动态 | Walker, M. R. | PDF | N/A | Temporal dynamics of viral fitness and the adaptive immune response in HCV infection | | 快速注意力信息通过人脑中的高频爆发进行传递 | Boroujeni, K. B. | PDF | N/A | Fast Attentional Information Routing via High-Frequency Bursts in the Human Brain | | 一种以可重复性为重点的单细胞转录组病例对照研究元分析方法揭示了稳健的差异表达基因 | Nakatsuka, N. J. | PDF | N/A | A Reproducibility Focused Meta-Analysis Method for Single-Cell Transcriptomic Case-Control Studies Uncovers Robust Differentially Expressed Genes | | 使用天然质谱法进行丙氨酸扫描以确定膜蛋白-脂质相互作用位点 | Jayasekera, H. S. | PDF | N/A | Alanine Scanning to Define Membrane Protein-Lipid Interaction Sites Using Native Mass Spectrometry | | 行为同步与发育时钟的巩固因秀丽隐杆线虫机械感觉回路的退化而受损 | Laufer, L. | PDF | N/A | Consolidation of behavioral synchronization with the developmental clock is impaired by the degeneration of a mechanosensory circuit in C. elegans | | 哺乳期大鼠的幼崽防御行为：伏隔核壳中潜在的神经肽信号及其相互作用 | Sanson, A. | PDF | N/A | Pup defence in lactating rats: The underlying neuropeptide signalling and their interactions in the nucleus accumbens shell | | GreedyMini：生成低密度DNA最小化器 | Golan, S. | PDF | N/A | GreedyMini: Generating low-density DNA minimizers | | Srs2/PARI DNA解旋酶在酵母和人类细胞中介导了对染色质桥的响应，从而抑制了细胞分裂过程中的脱落。 | Dam, M. | PDF | N/A | Srs2/PARI DNA helicase mediates abscission inhibition in response to chromatin bridges in yeast and human cells | | 哺乳动物大脑发育与进化中的双重计算系统 | Imam, N. | PDF | N/A | Dual Computational Systems in the Development and Evolution of Mammalian Brains | | 酵母中对杀手毒素K28的抗性依赖于COG复合物介导的防御因子Ktd1的运输。 | Laidlaw, K. | PDF | N/A | Killer Toxin K28 resistance in yeast relies on COG complex mediated trafficking of the defence factor Ktd1 | | GeneSetCluster 2.0：一个用于总结和整合基因集分析的综合工具集 | Ortega-Legarreta, A. | PDF | N/A | GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysis | | 碱性彗星试验中评估啮齿动物睾丸生殖细胞体内DNA损伤水平的方案 | Olsen, A.-K. | PDF | N/A | Protocol for assessing DNA damage levels in vivo in rodent testicular germ cells in the Alkaline Comet Assay | | YDS-Ternoplex：超越AlphaFold 3型模型，用于分子胶介导的三元复合物预测 | Che, X. | PDF | N/A | YDS-Ternoplex: Surpassing AlphaFold 3-Type Models for Molecular Glue-Mediated Ternary Complex Prediction | | 横跨美国本土的冠层高度模型与NAIP影像配对 | Allred, B. W. | PDF | N/A | Canopy height model and NAIP imagery pairs across CONUS | | 水平基因转移推断：基因存在-缺失优于基因树 | Mishra, S. | PDF | N/A | Horizontal Gene Transfer Inference: Gene presence-absence outperforms gene trees | | 在阿尔茨海默病神经病理学发病时的人体内嗅皮质细胞类型特异性分析 | Rodriguez-Rodriguez, P. | PDF | N/A | Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer's disease neuropathology | | 嵌合肽（GEP44）在饮食诱导的肥胖大鼠中减少体重、能量摄入和能量消耗 | Goldberg, M. E. | PDF | N/A | The Chimeric Peptide (GEP44) Reduces Body Weight and Both Energy Intake, and Energy Expenditure in Diet-Induced Obese Rats | | 开发用于Nextclade的禽流感A(H5)病毒数据集，能够快速准确地完成病毒分支的分配。 | Ort, J. T. | PDF | N/A | Development of avian influenza A(H5) virus datasets for Nextclade enables rapid and accurate clade assignment | | 稀疏测序技术允许对全基因组范围内的胞嘧啶修饰水平进行准确且高效的量化。 | Loo, C. E. | PDF | N/A | Sparse Sequencing permits accurate and efficient quantification of genome-wide cytosine modification levels | | 多层调控是嗅觉系统功能精确性和进化能力的基础。 | Mermet, J. | PDF | N/A | Multilayer regulation underlies the functional precision and evolvability of the olfactory system | | ntSynt-viz：跨多个基因组的共线性模式可视化 | Coombe, L. | PDF | N/A | ntSynt-viz: Visualizing synteny patterns across multiple genomes | | 与疾病相关的Kv1.3变异体在能量方面受损，导致新生链折叠功能受损。 | Deutsch, C. J. | PDF | N/A | Disease-associated Kv1.3 variants are energy compromised with impaired nascent chain folding. | | 有证据表明，SARS-CoV-2病毒的刺突蛋白（S蛋白）可能针对多种细胞骨架及细胞骨架相关蛋白的卷曲螺旋区域。 | Brezellec, P. | PDF | N/A | Evidence suggests that the SARS-CoV-2 Spike (S) protein may target coiled-coil regions of numerous cytoskeletal and cytoskeleton-associated proteins | | 对体内弹性应力传感器进行3D动态多尺度力与形态分析 | Jurado Jimenez, A. | PDF | N/A | 3D dynamic multiscale force and shape analysis of in-vivo elastic stress sensors | | TransBrain：一种用于在人类和小鼠之间转换全脑表型的计算框架 | Huang, S. | PDF | N/A | TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice | | 识别和治疗中枢神经系统外的CLN3疾病 | Ziolkowska, E. A. | PDF | N/A | Identifying and treating CLN3 disease outside the central nervous system | | ScaleSC：一种由GPU驱动的超快速且可扩展的单细胞RNA测序数据分析流程。 | Hu, W. | PDF | N/A | ScaleSC: A superfast and scalable single cell RNA-seq data analysis pipeline powered by GPU. | | 核氧还蛋白在垂体干细胞分化过程中调节WNT信号通路 | Brinkmeier, M. | PDF | N/A | Nucleoredoxin regulates WNT signaling during pituitary stem cell differentiation | | 对耐受锥虫和易感锥虫的牛在多个时间点和组织中感染刚果锥虫的功能基因组学研究 | McHugo, G. P. | PDF | N/A | Functional genomics of trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense across multiple time points and tissues | | 肠道-大脑液压系统：大脑运动和脑脊液循环是通过与腹部的机械耦合来驱动的。 | Garborg, C. S. | PDF | N/A | Gut-Brain Hydraulics: Brain motion and CSF circulation is driven by mechanical coupling with the abdomen | | 阿尔茨海默病和唐氏综合症细胞模型中的多胺生物合成失调 | Sola, A. | PDF | N/A | Polyamine biosynthesis dysregulation in Alzheimer's disease and Down syndrome cellular models | | 针对VatD的X射线片段筛选初步发现了对抗链阳霉素耐药性的线索。 | Asthana, P. | PDF | N/A | Initial leads to combat streptogramin resistance generated from X-ray fragment screening against VatD | | 在植物-微生物组反馈模型中，微生物入侵者的时间维度 | Parker, W. H. | PDF | N/A | Temporal dimensions of a microbial invader in a plant-microbiome feedback model | | 珍珠粟叶片离子组的遗传控制及其与根系和农艺性状的相关性 | Nakombo-Gbassault, P. | PDF | N/A | Genetic control of the leaf ionome in pearl millet and correlation with root and agromorphological traits | | 对比大麻科（Cannabaceae）家族中亚端粒卫星超家族的分布模式 | Horakova, L. | PDF | N/A | Contrasting patterns of subtelomeric satellite superfamily in the Cannabaceae family | | 在干旱胁迫期间，微生物接种对鼠尾草幼苗的影响具有环境依赖性 | Heil, J. A. | PDF | N/A | Context-dependent effects of microbial inoculation on sagebrush seedlings during drought stress | | 低相对空气湿度导致拟南芥的气孔更小、更密集，气孔比率更高。 | Tulva, I. | PDF | N/A | Low relative air humidity leads to smaller, denser stomata and higher stomatal ratios in Arabidopsis | | 缺乏AtMC1催化活性会引发依赖于NLR稳定性的自身免疫反应。 | Salguero-Linares, J. | PDF | N/A | Lack of AtMC1 catalytic activity triggers autoimmunity dependent on NLR stability | | 多个育性恢复基因座对由番茄中orf137引起的细胞质雄性不育的影响 | Iki, Y. | PDF | N/A | Multiple fertility restorer loci for cytoplasmic male sterility caused by orf137 in tomato | | 一种源自海藻糖酶的微生物相关分子模式（MAMP）在拟南芥中触发了LecRK-V介导的免疫反应。 | Iino, E. | PDF | N/A | A trehalase-derived MAMP triggers LecRK-V-mediated immune responses in Arabidopsis | | 两种豇豆Rubisco活化酶同工型对作物耐热性的影响 | Gjindali, A. | PDF | N/A | Two cowpea Rubisco activase isoforms for crop thermotolerance | | 阴离子聚合物稳定Cas9核糖核蛋白纳米颗粒，以提高植物原生质体中直接蛋白质递送和基因组编辑效率。 | Hubbard, J. | PDF | N/A | Anionic polymers stabilize Cas9 ribonucleoprotein nanoparticles to improve direct protein delivery and genome editing efficiencies in plant protoplasts | | 拟南芥中TARANI/泛素特异性蛋白酶-14相互作用蛋白的鉴定与表征 | Hegde, A. S. | PDF | N/A | Identification and Characterization of Interacting Proteins of TARANI/ Ubiquitin Specific Protease-14 in Arabidopsis thaliana | | IV类植物U-box蛋白功能冗余，以优化受体样细胞质激酶BIK1的蛋白质积累。 | Dou, R. | PDF | N/A | Class IV plant U-box proteins function redundantly to optimize protein accumulation of receptor-like cytoplasmic kinase BIK1 | | 拟南芥种子在采后成熟和吸胀过程中储存的mRNA及其翻译调控。 | Balarynova, J. | PDF | N/A | Arabidopsis seed stored mRNAs and translation regulation during post-harvest ripening and imbibition. | | 拟南芥根型铁氧还蛋白：NADP(H) 氧化还原酶对于根的生长和依赖铁氧还蛋白的过程至关重要。 | Monden, K. | PDF | N/A | Arabidopsis root-type ferredoxin:NADP(H) oxidoreductases are crucial for root growth and ferredoxin-dependent processes | | 多种假单胞菌属物种在猕猴桃种质资源中与猕猴桃病原菌Psa（Pseudomonas syringae pv. actinidiae）进行有益和抑制性的相互作用。 | Patterson, H. R. | PDF | N/A | Diverse Pseudomonas species engage in beneficial and suppressive interactions with the kiwifruit pathogen Psa across Actinidia germplasm | | 在夜幕的掩护下：根肿病如何影响拟南芥的夜间生理活动 | Garvetto, A. | PDF | N/A | Under the cover of darkness: how clubroot disease affects Arabidopsis thaliana physiology during the night | | 来自秘鲁瓦努科省的新种安祖花（天南星科） | Enikolopov, A. | PDF | N/A | New Species of Anthurium (Araceae) from Huanuco Department, Peru | | 激活替代氧化酶确保番茄果实成熟过程中乙烯和类胡萝卜素生物合成的碳供应 | Iglesias-Sanchez, A. | PDF | N/A | Activation of alternative oxidase ensures carbon supply for ethylene and carotenoid biosynthesis during tomato fruit ripening | | 近年来辐射物种中的分子与形态计量学方法：以Inga subnuda SALZM. EX BENTH和Inga vera WILLD.（豆科，含羞草亚科分支）为例 | Badia, C. C. V. | PDF | N/A | MOLECULAR AND MORPHOMETRIC APPROACHES IN RECENTLY RADIATED SPECIES: Inga subnuda SALZM. EX BENTH AND Inga vera WILLD. (LEGUMINOSAE, MIMOSOID CLADE) | | sciLaMA：一种单细胞表示学习框架，用于利用大型语言模型的先验知识 | Hu, H. | PDF | N/A | sciLaMA: A Single-Cell Representation Learning Framework to Leverage Prior Knowledge from Large Language Models | | USP7抑制在三阴性乳腺癌中干扰蛋白质稳态和肿瘤发生 | Kim, A. | PDF | N/A | USP7 inhibition perturbs proteostasis and tumorigenesis in triple negative breast cancer | | 人类RAP2A基因是果蝇不对称细胞分裂调节因子Rap2l的同源物，它靶向胶质母细胞瘤干细胞的干性特征。 | Franco, M. | PDF | N/A | Human RAP2A Homolog of the Drosophila Asymmetric Cell Division Regulator Rap2l Targets the Stemness of Glioblastoma Stem Cells | | 人类肠道微生物群与阿尔茨海默病发病机制的关联：一项探索性临床研究 | Ohara, T. | PDF | N/A | Association of human gut microbiota with Alzheimers disease pathogenesis: An exploratory clinical study | | 关于CA1区的涟漪振荡：重新评估异步性证据 | Scheffer Teixeira, R. | PDF | N/A | On CA1 ripple oscillations: reevaluating asynchronicity evidence | | 使用网络分析对马匹在积极和消极情绪预期下的面部表情和行为进行表征 | Phelipon, R. | PDF | N/A | Characterisation of facial expressions and behaviours of horses in response to positive and negative emotional anticipation using network analysis | | 靶向分枝杆菌转肽酶：评估Ldt和PBP抑制在抑制耻垢分枝杆菌中的作用 | de Munnik, M. | PDF | N/A | Targeting Mycobacterial Transpeptidases: Evaluating the Roles of Ldt and PBP Inhibition in Suppressing Mycobacterium smegmatis | | 多个自闭症小鼠模型中全脑连接性与嗅觉缺陷的共同改变 | Hsu, T.-T. | PDF | N/A | Shared Alteration of Whole-Brain Connectivity and Olfactory Deficits in Multiple Autism Mouse Models | | 以下是这段文字的中文翻译：

通过粘附G蛋白偶联受体脑特异性血管生成抑制剂2（BAI2/ADGRB2）调控海马兴奋性突触的发育

翻译说明： - Regulation：调控 - hippocampal：海马的 - excitatory synapse：兴奋性突触 - development：发育 - adhesion G-protein coupled receptor：粘附G蛋白偶联受体 - Brain-specific angiogenesis inhibitor 2 (BAI2/ADGRB2)：脑特异性血管生成抑制剂2（BAI2/ADGRB2）

希望这对你有帮助！ | Meyer, C. M. | PDF | N/A | Regulation of hippocampal excitatory synapse development by the adhesion G-protein coupled receptor Brain-specific angiogenesis inhibitor 2 (BAI2/ADGRB2) | | NeflE397K小鼠模型展示了与CMT2E一致的肌肉病理学和运动功能缺陷。 | Perez-Lopez, D. O. | PDF | N/A | The NeflE397K mouse model demonstrates muscle pathology and motor function deficits consistent with CMT2E | | 用于抑制人类来源的神经退行性疾病模型中Tau纤维传播的类蛋白质聚合物 | Longhini, A. P. | PDF | N/A | Protein-Like Polymer for Inhibition of Tau Fibril Propagation in Human-Derived Models of Neurodegeneration | | 发作后伽马振荡预测内侧颞叶癫痫中海马结构完整性 | Valdivia, D. | PDF | N/A | Post-Ictal Gamma Oscillations Predict Hippocampal Structural Integrity in Mesial Temporal Lobe Epilepsy | | Fmr1基因敲除通过调节HCN通道活性，导致内侧背丘脑皮层神经元的反弹尖峰时间延迟。 | Ordemann, G. J. J. | PDF | N/A | Fmr1 KO causes delayed rebound spike timing in mediodorsal thalamocortical neurons through regulation of HCN channel activity | | 视觉系统中单神经元生物物理学的多输出计算 | Seung, H. S. | PDF | N/A | Multi-output computation by single neuron biophysics in a visual system | | 一种用于量化报告基因荧光强度的开源图像分析方法 | Ball, K. F. | PDF | N/A | An Open-Source Image Analysis Method for Quantifying Reporter Fluorescence | | ZPA调控序列（ZRS）的3'区域是活性所必需的，并且含有一个关键的E-box。 | Ball, K. F. | PDF | N/A | The 3' Region of the ZPA Regulatory Sequence (ZRS) is required for activity and contains a critical E-box | | 在卵母细胞到受精卵的转变过程中，线粒体自噬促进了物种的永生。 | Balachandar Thendral, S. | PDF | N/A | Mitophagy at the oocyte-to-zygote transition promotes species immortality | | HIF1α调控肌腱对过度负荷的反应，并在不依赖血管募集的情况下驱动肌腱病变。 | Moschini, G. | PDF | N/A | HIF1α gates tendon response to overload and drives tendinopathy independently of vascular recruitment | | AKAP12变体1敲除增强了血管内皮细胞的运动能力 | Ali, A. | PDF | N/A | AKAP12 variant 1 knockout enhances vascular endothelial cell motility | | 未分化及经视黄酸分化的HL-60/S4细胞在有无LBR敲低情况下的表型变化 | Olins, A. L. | PDF | N/A | Phenotypic Changes in Undifferentiated and Retinoic Acid Differentiated HL-60/S4 Cells with-or-without LBR Knockdown | | 血小板内吞作用和α-颗粒货物包装对于正常皮肤伤口愈合至关重要 | Coenen, D. M. | PDF | N/A | Platelet endocytosis and α-granule cargo packaging are essential for normal skin wound healing | | 斑马鱼视网膜再生过程中衰老分泌组的分析 | Konar, G. J. | PDF | N/A | Analysis of The Senescence Secretome During Zebrafish Retina Regeneration | | SBIS，一种新型橙色荧光活体探针，用于褐藻细胞的四维成像。 | Zilliox, M. | PDF | N/A | SBIS, a new orange fluorescent vital probe for the 4D imaging of brown algal cells | | 端粒酶mRNA减少辐射诱导的人类皮肤DNA损伤 | Chang, D. F. | PDF | N/A | Telomerase mRNA Reduces Radiation-induced DNA Damage of human skin | | 有氧运动减少了雌性猪心外膜脂肪组织中炎症性M1巨噬细胞和CD8+ T细胞的数量及其转录表达。 | Ahmad, I. | PDF | N/A | Aerobic exercise decreases the number and transcript expression of inflammatory M1 macrophages and CD8+ T cells in the epicardial adipose tissue of female pigs | | FUS转录后剪接通过RNA凝聚实现自我调节，具有治疗ALS-FUS的潜力。 | Huang, W.-P. | PDF | N/A | FUS post-transcriptional splicing is autoregulated via RNA condensation with therapeutic potential for ALS-FUS | | 按需递送纤维蛋白-1（fibulin-1）能够实现基底膜的重复拉伸。 | Soh, A. W. J. | PDF | N/A | On-demand delivery of fibulin-1 enables repeated basement membrane stretching | | SRS显微镜技术揭示了热量限制通过抑制卵黄生成来延长秀丽隐杆线虫寿命的机制。 | Yang, B. | PDF | N/A | SRS microscopy identifies inhibition of vitellogenesis as a mediator of lifespan extension by caloric restriction in C. elegans | | 使用真实和合成的冷冻电子断层扫描数据训练通用分割网络。 | Purnell, C. | PDF | N/A | Training Generalized Segmentation Networks with Real and Synthetic Cryo-ET data. | | 将这段翻译成中文是：重新利用监管毒理学安全数据以识别潜在的延长寿命物质。 | Miwa, S. | PDF | N/A | Repurposing Regulatory Toxicology Safety Data to Identify Potential Pro-Longevity Substances | | YY1蛋白对于促进穆勒胶质细胞重编程和视网膜再生至关重要。 | Chaudhary, M. | PDF | N/A | YY1 protein is essential for the promotion of Muller glia reprogramming and retina regeneration | | 基质金属蛋白酶在凝胶样发育不良中对细胞迁移的失调作用 | Morales, A. A. | PDF | N/A | Dysregulation of cell migration by matrix metalloproteinases in geleophysic dysplasia | | 多动力蛋白簇施加的机械应力揭示了细胞内微管断裂的机制 | Geng, Q. | PDF | N/A | Multi-kinesin clusters impart mechanical stress that reveals mechanisms of microtubule breakage in cells | | 诺拉病毒在分裂的肠道干细胞中增殖，并使果蝇对肠道感染和氧化应激敏感。 | Franchet, A. | PDF | N/A | Nora virus proliferates in dividing intestinal stem cells and sensitizes flies to intestinal infection and oxidative stress | | 使用300mT/m梯度在人体心脏中进行体内心脏扩散峰度成像 | Afzali, M. | PDF | N/A | Cardiac diffusion kurtosis imaging in the human heart in vivo using 300mT/m gradients | | 小鼠内皮细胞线粒体Opa1相关融合的改变加剧了与年龄相关的血管和肾脏损伤 | Turnaturi, C. | PDF | N/A | Altered endothelial mitochondrial Opa1-related fusion in mouse amplifies age-associated vascular and kidney damages | | 脓毒症诱导的脂滴积累增强抗菌先天免疫 | Pereira-Dutra, F. S. | PDF | N/A | SEPSIS-INDUCED LIPID DROPLET ACCUMULATION ENHANCES ANTIBACTERIAL INNATE IMMUNITY | | 铜绿假单胞菌补体抵抗组的菌株特异性变异 | Janet-Maitre, M. | PDF | N/A | Strain-Specific Variation in the Complement Resistome of Pseudomonas aeruginosa | | 通过亚基间相互作用调控噬菌体{varphi}29的有序DNA易位周期 | Dargis, R. | PDF | N/A | Regulation of Ordinal DNA Translocation Cycle in Bacteriophage {varphi}29 through Trans-Subunit Interactions | | ## 多级溶剂萃取法提取的特色茶提取物的生化成分

摘要： 本研究采用多级溶剂萃取法，结合不同溶剂处理，从特色茶中提取了多种生化成分。通过分析提取物的化学成分，探讨了不同溶剂对特色茶中活性成分提取效率的影响，为特色茶的深度开发和利用提供了理论依据。

关键词： 特色茶；多级萃取；溶剂处理；生化成分

正文：

特色茶因其独特的风味和潜在的保健功效而备受关注。为了更好地开发利用特色茶资源，本研究采用多级溶剂萃取法，结合不同溶剂处理，对特色茶中的生化成分进行了提取和分析。

1. 材料与方法

1.1 材料与试剂: 简述所用特色茶种类、来源，以及实验所用溶剂、试剂等信息。
1.2 仪器与设备: 列出实验所用主要仪器设备及其型号。
1.3 实验方法:
- 1.3.1 样品预处理: 描述茶叶的粉碎、过筛等预处理步骤。
- 1.3.2 多级溶剂萃取: 详细说明多级溶剂萃取的步骤，包括所用溶剂种类、萃取顺序、萃取时间、温度等参数。
- 1.3.3 提取物浓缩与干燥: 描述提取物的浓缩、干燥方法。
- 1.3.4 生化成分分析: 列出所分析的生化成分种类，并简述所采用的检测方法，如高效液相色谱法（HPLC）、气相色谱-质谱联用法（GC-MS）等。

2. 结果与讨论

2.1 不同溶剂提取物的得率: 比较不同溶剂处理下特色茶提取物的得率，分析溶剂极性对提取效率的影响。
2.2 提取物中主要生化成分的含量: 列出并分析不同溶剂提取物中主要生化成分（如茶多酚、咖啡碱、氨基酸、可溶性糖等）的含量，探讨不同溶剂对特定成分的选择性提取能力。
2.3 提取物的抗氧化活性: 测定不同溶剂提取物的抗氧化活性（如DPPH自由基清除率、FRAP值等），分析生化成分与抗氧化活性之间的相关性。

3. 结论

总结不同溶剂处理对特色茶生化成分提取效率的影响，并指出最具潜力的溶剂组合。展望特色茶提取物在食品、医药等领域的应用前景。

参考文献: 列出所有引用的文献。

注：以上只是一个简单的框架，你需要根据你的具体研究内容进行修改和完善。

你需要提供更具体的信息，例如：

你使用的特色茶种类
你使用的溶剂种类
你分析的生化成分种类
你得到的实验结果

这样我才能帮你翻译出更准确、更完整的内容。 | Kipsura, E. | PDF | N/A | BIOCHEMICAL COMPOSITION OF SPECIALTY TEA EXTRACTS FROM MULTISTAGE EXTRACTIONS USING SOLVENTS TREATMENTS | | SVCFit：推断肿瘤中结构变异的细胞分数 | Liu, Y. | PDF | N/A | SVCFit: Inferring structural variant cellular fraction in tumors | | GeNePi：一种用于全基因组测序分析的GPU增强型下一代生物信息学流程 | Marangoni, S. | PDF | N/A | GeNePi: a GPU-enhanced Next Generation Bioinformatics Pipeline for Whole Genome Sequencing Analysis | | 一个未清理的样本，实验食物残渣中食物输入与回收的蛋白质信号之间存在差异。 | Dekker, J. A. A. | PDF | N/A | An unclean slate, discrepancies between food input and recovered protein signal from experimental foodcrusts | | 奥丁古菌门中双FtsZ蛋白独特的丝状形态和膜连接特征 | Kumari, J. | PDF | N/A | Distinct filament morphology and membrane tethering features of the dual FtsZs in Odinarchaeota | | 从荧光时间序列推断结合动力学的贝叶斯方法 | Bryan, J. S. | PDF | N/A | Bayesian Inference of Binding Kinetics from Fluorescence Time Series | | 将RIPK1选择性苯并氧氮杂环庚烷-4-酮骨架重新利用，用于开发III型LIMK1/2抑制剂 | Mandel, S. | PDF | N/A | Repurposing of the RIPK1 selective benzooxazepin-4-one scaffold for the development of a type-III LIMK1/2 inhibitor | | 针对CYLD皮肤综合征中的非经典NF-κB信号通路，通过选择性抑制IκB激酶α进行治疗。 | Hodgson, K. | PDF | N/A | Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha. | | 对一种乳制品分离物进行测序，揭示了马克斯克鲁维酵母（Kluyveromyces marxianus）作为乳糖价值化宿主的潜力。 | Thornbury, M. | PDF | N/A | Sequencing of a dairy isolate unlocks Kluyveromyces marxianus as a host for lactose valorization | | 鳞胁秋沙鸭（Mergus squamatus）与普通秋沙鸭（M. merganser）羽毛微观结构的差异 | Li, D. | PDF | N/A | Differences between Scaly-sided Merganser (Mergus squamatus) and Common Merganser (M. merganser) feather microstructure | | SQ109对多种真菌的广谱活性及其作用机制 | Malwal, S. R. | PDF | N/A | Broad-Spectrum Activity and Mechanisms of Action of SQ109 on a Variety of Fungi | | 酵母菌落生物膜中的意外与调控细胞死亡 | Netherwood, D. J. | PDF | N/A | Accidental and Regulated Cell Death in Yeast Colony Biofilms | | 环境和体重等级与人工饲养下幼年东部大鲵（Cryptobranchus alleganiensis alleganiensis）皮肤微生物组结构相关 | Aplasca, A. C. | PDF | N/A | Environment and weight class linked to skin microbiome structure of juvenile Eastern hellbenders (Cryptobranchus alleganiensis alleganiensis) in human care | | 用于治疗目的的噬菌体纯化采用CIMmultus整体OH柱色谱法 | Echterhof, A. | PDF | N/A | Bacteriophage purification using CIMmultus monolithic OH-column chromatography for therapeutic purposes | | C3H-HeN作为一种具有TLR4功能的亚致死性钩端螺旋体病小鼠模型 | Abil, O. Z. | PDF | N/A | C3H-HeN as a TLR4 competent mouse model of sublethal leptospirosis | | 使用机器学习方法从图像中预测微生物组分类学的表征 | Niese, B. | PDF | N/A | Predicting characterization of microbiome taxonomy from imaging using machine learning approaches | | 细胞外囊泡的产生和膜摄取促进了大肠杆菌的修复和抗生素耐受性。 | Bos, J. | PDF | N/A | Extracellular vesicle production and membrane uptake promote repair and antibiotic tolerance in E. coli | | 以下是这段文字的中文翻译：

关于Nasonia黄蜂中doublesex依赖性性别分化的转录控制模型

翻译说明： - "transcriptional control model" 翻译为 "转录控制模型"，指的是基因表达调控的模型。 - "doublesex-dependent" 翻译为 "doublesex依赖性"，doublesex 是一种在昆虫性别分化中起关键作用的基因。 - "sex differentiation" 翻译为 "性别分化"，指生物体从原始性腺发育为特定性别的过程。 - "Nasonia wasps" 翻译为 "Nasonia黄蜂"，Nasonia 是一种寄生蜂，常用于发育生物学和遗传学研究。

果蝇（Drosophila melanogaster）天然RNA聚合酶II转录复合物和核小体的结构表征

翻译说明： - "Structural Characterization" 翻译为“结构表征”，指对分子结构的研究和描述。 - "Native" 翻译为“天然的”，表示研究对象是未经人工修饰的天然状态。 - "RNA Polymerase II Transcription Complexes" 翻译为“RNA聚合酶II转录复合物”，指参与转录过程的RNA聚合酶II及其相关蛋白质复合物。 - "Nucleosomes" 翻译为“核小体”，是染色质的基本结构单位。 - "Drosophila melanogaster" 翻译为“果蝇”，是一种常用的模式生物。

medRxiv

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考察科学作者身份中的性别和种族差异，以促进大学公共卫生学院的公平、多样性和包容性文化。	Christen, P.	PDF	N/A	Examining gender and ethnic disparities in scientific authorship to promote a culture of equity, diversity and inclusion at a university school of public health
无偏倚的多组学网络数据整合方法能够实现对心力衰竭患者进行临床相关结果预测的聚类分析。	Esenkova, E. E.	PDF	N/A	Unbiased multi-omics network-based data integration allows clinically relevant outcome-predicting clustering of individuals with heart failure
经肺蛋白质组梯度揭示了心力衰竭中肺血管疾病发展所涉及的途径	Melenovsky, V.	PDF	N/A	Transpulmonary proteome gradients identify pathways involved in the development of pulmonary vascular disease in heart failure
外周静脉压准确评估缩窄性心包炎的充血情况	Xia, X.	PDF	N/A	Peripheral Venous Pressure Accurately Evaluates Congestion in Constrictive pericarditis
Sam68通过抑制心肌细胞葡萄糖氧化加剧病理性心脏肥大	An, J.	PDF	N/A	Sam68 Exacerbates Pathological Cardiac Hypertrophy by Suppressing Cardiomyocyte Glucose Oxidation
使用自然语言转换器和深度学习模型从全景X光片中对儿童牙科疾病进行分类	Pham, T.	PDF	N/A	Classification of Pediatric Dental Diseases from Panoramic Radiographs using Natural Language Transformer and Deep Learning Models
2018-2023年间，某大型城市卫生系统中儿童哮喘的严重程度、病毒传播的重要性以及环境暴露的影响日益增加。	McCuskee, S.	PDF	N/A	Increasing severity, importance of viral transmission, and environmental exposures for pediatric asthma in a large urban health system, 2018-2023
人类中FGF21的线粒体与应激相关心理生物学调控	Kurade, M.	PDF	N/A	Mitochondrial and Stress-Related Psychobiological Regulation of FGF21 in Humans
ImputeBench：单插补方法基准测试	Richter, R.	PDF	N/A	ImputeBench: Benchmarking Single Imputation Methods
《猴痘流行病的建模：阈值、时间动态及天花疫苗接种后的免疫力衰减》	Jackson, S. Y.	PDF	N/A	Modeling Monkeypox Epidemics: Thresholds, Temporal Dynamics, and Waning Immunity from Smallpox Vaccination.
工作期望与心理困扰中的性别差异：来自美国和韩国的见解	Dang, L.	PDF	N/A	Gender Differences in Work Expectations and Psychological Distress: Insights from the United States and South Korea
耦合蚊媒疾病与蚊虫预防行为的传播模型的平衡特性	Poterek, M. L.	PDF	N/A	Equilibrium properties of a coupled contagion model of mosquito-borne disease and mosquito preventive behaviors
英国初级保健中慢性非癌性疼痛患者长期阿片类药物治疗及后续停药趋势：一项回顾性队列研究	Cai, Q.	PDF	N/A	Trends of long-term opioid therapy and subsequent discontinuation among people with chronic non-cancer pain in UK primary care: a retrospective cohort study
身体形象、肥胖与性凝聚力：对尼日利亚大学生抑郁的影响	Akinyemi, O.	PDF	N/A	Body Image, Obesity, and Sexual Cohesion: Impacts on Depression among Nigerian University Students
儿童时期的异食癖：并发及连续的精神疾病共病	Rubino, L.	PDF	N/A	Pica in childhood: concurrent and sequential psychiatric comorbidity
父母与子女之间的情感纽带与学龄前儿童社会情感问题的纵向关联：母亲与父亲的独特及共同作用	Hatakka, E.	PDF	N/A	Longitudinal associations between parental bonding and child preschool social-emotional problems: The unique and combined role of mothers and fathers
墨西哥城COVID-19疫情期间医院需求的复杂性	de Anda-Jauregui, G.	PDF	N/A	Complexity of hospital demand during the COVID-19 pandemic in Mexico City
以下是这段英文的中文翻译：

运动相关脑震荡后的时间进程反应：一项多模态研究